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David Ron

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
38
Harding, Heather
20
Zhang, Yuhong
13
Habener, Joel
11
Novoa, Isabel
9
Jousse, Céline
9
Aaronson, Stuart
9
Urano, Fumihiko
9
brasier, allan
8
Zinszner, H
8
Zeng, Huiqing
8
Kaufman, Randal
8
Scheuner, Donalyn
7
Rubin, Jeffrey
7
Sher, Ifat
7
Sok, John

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Publications

TOP 3
Li Gang; Mongillo Marco; Chin King-Tung; Harding Heather; Ron David; Marks Andrew R; Tabas Ira
Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis.
Thorp Edward; Li Gang; Seimon Tracie A; Kuriakose George; Ron David; Tabas Ira
Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.
Wiseman R Luke; Chin King-Tung; Haynes Cole M; Stanhill Ariel; Xu Chong-Feng; Roguev Assen; Krogan Nevan J; Neubert Thomas A; Ron David
Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle.

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All Publications

2009: Li Gang; Mongillo Marco; Chin King-Tung; Harding Heather; Ron David; Marks Andrew R; Tabas Ira
Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis.
The Journal of cell biology 2009;186(6):783-92.
2009: Thorp Edward; Li Gang; Seimon Tracie A; Kuriakose George; Ron David; Tabas Ira
Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.
Cell metabolism 2009;9(5):474-81.
2009: Wiseman R Luke; Chin King-Tung; Haynes Cole M; Stanhill Ariel; Xu Chong-Feng; Roguev Assen; Krogan Nevan J; Neubert Thomas A; Ron David
Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle.
The Journal of biological chemistry 2009;284(22):15233-45.
2009: Harding Heather P; Zhang Yuhong; Scheuner Donalyn; Chen Jane-Jane; Kaufman Randal J; Ron David
Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):1832-7.
2008: Petrova Kseniya; Oyadomari Seiichi; Hendershot Linda M; Ron David
Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3.
The EMBO journal 2008;27(21):2862-72.
2008: Song Benbo; Scheuner Donalyn; Ron David; Pennathur Subramaniam; Kaufman Randal J
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes.
The Journal of clinical investigation 2008;118(10):3378-89.
2008: Oyadomari Seiichi; Harding Heather P; Zhang Yuhong; Oyadomari Miho; Ron David
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice.
Cell metabolism 2008;7(6):520-32.
2008: Yun Chi; Stanhill Ariel; Yang Yun; Zhang Yuhong; Haynes Cole M; Xu Chong-Feng; Neubert Thomas A; Mor Adam; Philips Mark R; Ron David
Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):7094-9.
2008: Harding Heather P; Lackey Jeremy G; Hsu Hao-Chi; Zhang Yuhong; Deng Jing; Xu Rui-Ming; Damha Masad J; Ron David
An intact unfolded protein response in Trpt1 knockout mice reveals phylogenic divergence in pathways for RNA ligation.
RNA (New York, N.Y.) 2008;14(2):225-32.
2008: Ron David; Hubbard Stevan R
How IRE1 reacts to ER stress.
Cell 2008;132(1):24-6.
2008: Lackey Jeremy G; Ron David; Damha Masad J; Harding Heather P
Toward the discovery of new antifungal agents: the design and validation of a novel 2'P-RNA probe and high throughput screening assay against 2'-phosphotransferase Tpt1p.
Nucleic acids symposium series (2004) 2008;(52):475-6.
2007: Haynes Cole M; Petrova Kseniya; Benedetti Cristina; Yang Yun; Ron David
ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans.
Developmental cell 2007;13(4):467-80.
2007: Zisman-Rozen S; Fink D; Ben-Izhak O; Fuchs Y; Brodski A; Kraus M H; Bejar J; Ron D
Downregulation of Sef, an inhibitor of receptor tyrosine kinase signaling, is common to a variety of human carcinomas.
Oncogene 2007;26(41):6093-8.
2007: Ron David; Walter Peter
Signal integration in the endoplasmic reticulum unfolded protein response.
Nature reviews. Molecular cell biology 2007;8(7):519-29.
2006: Shaoul Ron; Eliahu Liat; Sher Ifat; Hamlet Yaheli; Miselevich Ines; Goldshmidt Orit; Ron Dina
Elevated expression of FGF7 protein is common in human gastric diseases.
Biochemical and biophysical research communications 2006;350(4):825-33.
2006: Ziv Inbal; Fuchs Yaron; Preger Ella; Shabtay Ariel; Harduf Haggar; Zilpa Tal; Dym Naama; Ron Dina
The human sef-a isoform utilizes different mechanisms to regulate receptor tyrosine kinase signaling pathways and subsequent cell fate.
The Journal of biological chemistry 2006;281(51):39225-35.
2006: Blais Jaime D; Addison Christina L; Edge Robert; Falls Theresa; Zhao Huijun; Wary Kishore; Koumenis Costas; Harding Heather P; Ron David; Holcik Martin; Bell John C
Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress.
Molecular and cellular biology 2006;26(24):9517-32.
2006: Stanhill Ariel; Haynes Cole M; Zhang Yuhong; Min Guangwei; Steele Matthew C; Kalinina Juliya; Martinez Enid; Pickart Cecile M; Kong Xiang-Peng; Ron David
An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity.
Molecular cell 2006;23(6):875-85.
2006: Benedetti Cristina; Haynes Cole M; Yang Yun; Harding Heather P; Ron David
Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response.
Genetics 2006;174(1):229-39.
2006: Oyadomari Seiichi; Yun Chi; Fisher Edward A; Kreglinger Nicola; Kreibich Gert; Oyadomari Miho; Harding Heather P; Goodman Alan G; Harant Hanna; Garrison Jennifer L; Taunton Jack; Katze Michael G; Ron David
Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload.
Cell 2006;126(4):727-39.
2006: Ron David
Cell biology. Stressed cells cope with protein overload.
Science (New York, N.Y.) 2006;313(5783):52-3.
2006: Ron David; Hinnebusch Alan G
Targeting translation in hypoxic tumors.
ACS chemical biology 2006;1(3):145-8.
2006: Sher Ifat; Zisman-Rozen Simona; Eliahu Liat; Whitelock John M; Maas-Szabowski Nicole; Yamada Yoshihiko; Breitkreutz Dirk; Fusenig Norbert E; Arikawa-Hirasawa Eri; Iozzo Renato V; Bergman Reuven; Ron Dina
Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation.
The Journal of biological chemistry 2006;281(8):5178-87.
2006: Marciniak Stefan J; Garcia-Bonilla Lidia; Hu Junjie; Harding Heather P; Ron David
Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK.
The Journal of cell biology 2006;172(2):201-9.
2005: Harding Heather P; Zhang Yuhong; Khersonsky Sonya; Marciniak Stefan; Scheuner Donalyn; Kaufman Randal J; Javitt Norman; Chang Young-Tae; Ron David
Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression.
Cell metabolism 2005;2(6):361-71.
2005: Silva Robert M; Ries Vincent; Oo Tinmarla Frances; Yarygina Olga; Jackson-Lewis Vernice; Ryu Elizabeth J; Lu Phoebe D; Marciniak Stefan J; Ron David; Przedborski Serge; Kholodilov Nikolai; Greene Lloyd A; Burke Robert E
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism.
Journal of neurochemistry 2005;95(4):974-86.
2005: Maurin Anne-Catherine; Jousse Céline; Balage Michelle; Averous Julien; Parry Laurent; Bruhat Alain; Cherasse Yoan; Zeng Huiqing; Zhang Yuhong; Harding Heather; Ron David; Fafournoux Pierre
[GCN2 regulates feeding behavior to maintain amino acid homeostasis in omnivores]
Médecine sciences : M/S 2005;21(10):799-801.
2005: Bi Meixia; Naczki Christine; Koritzinsky Marianne; Fels Diane; Blais Jaime; Hu Nianping; Harding Heather; Novoa Isabelle; Varia Mahesh; Raleigh James; Scheuner Donalyn; Kaufman Randal J; Bell John; Ron David; Wouters Bradly G; Koumenis Constantinos
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth.
The EMBO journal 2005;24(19):3470-81.
2005: Costa-Mattioli Mauro; Gobert Delphine; Harding Heather; Herdy Barbara; Azzi Mounia; Bruno Martin; Bidinosti Michael; Ben Mamou Cyrinne; Marcinkiewicz Edwige; Yoshida Madoka; Imataka Hiroaki; Cuello A Claudio; Seidah Nabil; Sossin Wayne; Lacaille Jean-Claude; Ron David; Nader Karim; Sonenberg Nahum
Translational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2.
Nature 2005;436(7054):1166-73.
2005: Harduf Haggar; Halperin Einat; Reshef Ram; Ron Dina
Sef is synexpressed with FGFs during chick embryogenesis and its expression is differentially regulated by FGFs in the developing limb.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;233(2):301-12.
2005: Maurin Anne-Catherine; Jousse Céline; Averous Julien; Parry Laurent; Bruhat Alain; Cherasse Yoan; Zeng Huiqing; Zhang Yuhong; Harding Heather P; Ron David; Fafournoux Pierre
The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores.
Cell metabolism 2005;1(4):273-7.
2005: West David C; Rees Chris G; Duchesne Laurence; Patey Susannah J; Terry Carla J; Turnbull Jeremy E; Delehedde Maryse; Heegaard Christian W; Allain Fabrice; Vanpouille Christophe; Ron Dina; Fernig David G
Interactions of multiple heparin binding growth factors with neuropilin-1 and potentiation of the activity of fibroblast growth factor-2.
The Journal of biological chemistry 2005;280(14):13457-64.
2005: Boyce Michael; Bryant Kevin F; Jousse Céline; Long Kai; Harding Heather P; Scheuner Donalyn; Kaufman Randal J; Ma Dawei; Coen Donald M; Ron David; Yuan Junying
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress.
Science (New York, N.Y.) 2005;307(5711):935-9.
2004: Marciniak Stefan J; Yun Chi Y; Oyadomari Seiichi; Novoa Isabel; Zhang Yuhong; Jungreis Rivka; Nagata Kazuhiro; Harding Heather P; Ron David
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.
Genes & development 2004;18(24):3066-77.
2004: Deng Jing; Lu Phoebe D; Zhang Yuhong; Scheuner Donalyn; Kaufman Randal J; Sonenberg Nahum; Harding Heather P; Ron David
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2.
Molecular and cellular biology 2004;24(23):10161-8.
2004: Lu Phoebe D; Harding Heather P; Ron David
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response.
The Journal of cell biology 2004;167(1):27-33.
2004: Ron David; Hampton Randolph Y
Membrane biogenesis and the unfolded protein response.
The Journal of cell biology 2004;167(1):23-5.
2004: Ron David; Oyadomari Seiichi
Lipid phase perturbations and the unfolded protein response.
Developmental cell 2004;7(3):287-8.
2004: Blais Jaime D; Filipenko Vasilisa; Bi Meixia; Harding Heather P; Ron David; Koumenis Costas; Wouters Bradly G; Bell John C
Activating transcription factor 4 is translationally regulated by hypoxic stress.
Molecular and cellular biology 2004;24(17):7469-82.
2004: Yoneda Takunari; Benedetti Cristina; Urano Fumihiko; Clark Scott G; Harding Heather P; Ron David
Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones.
Journal of cell science 2004;117(Pt 18):4055-66.
2004: Ye Yihong; Shibata Yoko; Yun Chi; Ron David; Rapoport Tom A
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol.
Nature 2004;429(6994):841-7.
2004: Preger Ella; Ziv Inbal; Shabtay Ariel; Sher Ifat; Tsang Michael; Dawid Igor B; Altuvia Yael; Ron Dina
Alternative splicing generates an isoform of the human Sef gene with altered subcellular localization and specificity.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1229-34.
2004: Lu Phoebe D; Jousse Céline; Marciniak Stefan J; Zhang Yuhong; Novoa Isabel; Scheuner Donalyn; Kaufman Randal J; Ron David; Harding Heather P
Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2.
The EMBO journal 2004;23(1):169-79.
2003: Jousse Céline; Oyadomari Seiichi; Novoa Isabel; Lu Phoebe; Zhang Yuhong; Harding Heather P; Ron David
Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells.
The Journal of cell biology 2003;163(4):767-75.
2003: Sher Ifat; Yeh Brian K; Mohammadi Moosa; Adir Noam; Ron Dina
Structure-based mutational analyses in FGF7 identify new residues involved in specific interaction with FGFR2IIIb.
FEBS letters 2003;552(2-3):150-4.
2003: Feng Bo; Yao Pin Mei; Li Yankun; Devlin Cecilia M; Zhang Dajun; Harding Heather P; Sweeney Michele; Rong James X; Kuriakose George; Fisher Edward A; Marks Andrew R; Ron David; Tabas Ira
The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages.
Nature cell biology 2003;5(9):781-92.
2003: Harding Heather P; Zhang Yuhong; Zeng Huiquing; Novoa Isabel; Lu Phoebe D; Calfon Marcella; Sadri Navid; Yun Chi; Popko Brian; Paules Richard; Stojdl David F; Bell John C; Hettmann Thore; Leiden Jeffrey M; Ron David
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress.
Molecular cell 2003;11(3):619-33.
2003: Novoa Isabel; Zhang Yuhong; Zeng Huiqing; Jungreis Rivka; Harding Heather P; Ron David
Stress-induced gene expression requires programmed recovery from translational repression.
The EMBO journal 2003;22(5):1180-7.
2003: Yeh Brian K; Igarashi Makoto; Eliseenkova Anna V; Plotnikov Alexander N; Sher Ifat; Ron Dina; Aaronson Stuart A; Mohammadi Moosa
Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2266-71.
2002: Ryu Elizabeth J; Harding Heather P; Angelastro James M; Vitolo Ottavio V; Ron David; Greene Lloyd A
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(24):10690-8.
2002: Harding Heather P; Ron David
Endoplasmic reticulum stress and the development of diabetes: a review.
Diabetes 2002;51 Suppl 3():S455-61.
2002: Ron David
Translational control in the endoplasmic reticulum stress response.
The Journal of clinical investigation 2002;110(10):1383-8.
2002: Urano Fumihiko; Calfon Marcella; Yoneda Takunari; Yun Chi; Kiraly Moni; Clark Scott G; Ron David
A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response.
The Journal of cell biology 2002;158(4):639-46.
2002: Deng Jing; Harding Heather P; Raught Brian; Gingras Anne-Claude; Berlanga Juan Jose; Scheuner Donalyn; Kaufman Randal J; Ron David; Sonenberg Nahum
Activation of GCN2 in UV-irradiated cells inhibits translation.
Current biology : CB 2002;12(15):1279-86.
2002: Yoneda Takunari; Urano Fumihiko; Ron David
Transmission of proteotoxicity across cellular compartments.
Genes & development 2002;16(11):1307-13.
2002: Ron David
Proteotoxicity in the endoplasmic reticulum: lessons from the Akita diabetic mouse.
The Journal of clinical investigation 2002;109(4):443-5.
2002: Calfon Marcella; Zeng Huiqing; Urano Fumihiko; Till Jeffery H; Hubbard Stevan R; Harding Heather P; Clark Scott G; Ron David
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA.
Nature 2002;415(6867):92-6.
2002: Ostrovsky Olga; Berman Bluma; Gallagher John; Mulloy Barbara; Fernig David G; Delehedde Maryse; Ron Dina
Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes.
The Journal of biological chemistry 2002;277(4):2444-53.
2002: Harding Heather P; Calfon Marcella; Urano Fumihiko; Novoa Isabel; Ron David
Transcriptional and translational control in the Mammalian unfolded protein response.
Annual review of cell and developmental biology 2002;18():575-99.
2001: Jousse C; Bruhat A; Carraro V; Urano F; Ferrara M; Ron D; Fafournoux P
Inhibition of CHOP translation by a peptide encoded by an open reading frame localized in the chop 5'UTR.
Nucleic acids research 2001;29(21):4341-51.
2001: Bertolotti A; Ron D
Alterations in an IRE1-RNA complex in the mammalian unfolded protein response.
Journal of cell science 2001;114(Pt 17):3207-12.
2001: Harding H P; Zeng H; Zhang Y; Jungries R; Chung P; Plesken H; Sabatini D D; Ron D
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival.
Molecular cell 2001;7(6):1153-63.
2001: Novoa I; Zeng H; Harding H P; Ron D
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha.
The Journal of cell biology 2001;153(5):1011-22.
2001: Ron D
Hyperhomocysteinemia and function of the endoplasmic reticulum.
The Journal of clinical investigation 2001;107(10):1221-2.
2001: Bertolotti A; Wang X; Novoa I; Jungreis R; Schlessinger K; Cho J H; West A B; Ron D
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice.
The Journal of clinical investigation 2001;107(5):585-93.
2001: Sok J; Calfon M; Lu J; Lichtlen P; Clark S G; Ron D
Arsenite-inducible RNA-associated protein (AIRAP) protects cells from arsenite toxicity.
Cell stress & chaperones 2001;6(1):6-15.
2001: Harding H P; Novoa I; Bertolotti A; Zeng H; Zhang Y; Urano F; Jousse C; Ron D
Translational regulation in the cellular response to biosynthetic load on the endoplasmic reticulum.
Cold Spring Harbor symposia on quantitative biology 2001;66():499-508.
2001: Ma Y; Lu Y; Zeng H; Ron D; Mo W; Neubert T A
Characterization of phosphopeptides from protein digests using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and nanoelectrospray quadrupole time-of-flight mass spectrometry.
Rapid communications in mass spectrometry : RCM 2001;15(18):1693-700.
2000: Harding H P; Novoa I; Zhang Y; Zeng H; Wek R; Schapira M; Ron D
Regulated translation initiation controls stress-induced gene expression in mammalian cells.
Molecular cell 2000;6(5):1099-108.
2000: Urano F; Bertolotti A; Ron D
IRE1 and efferent signaling from the endoplasmic reticulum.
Journal of cell science 2000;113 Pt 21():3697-702.
2000: Sher I; Lang T; Lubinsky-Mink S; Kuhn J; Adir N; Chatterjee S; Schomburg D; Ron D
Identification of residues important both for primary receptor binding and specificity in fibroblast growth factor-7.
The Journal of biological chemistry 2000;275(45):34881-6.
2000: Bertolotti A; Zhang Y; Hendershot L M; Harding H P; Ron D
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response.
Nature cell biology 2000;2(6):326-32.
2000: Harding H P; Zhang Y; Bertolotti A; Zeng H; Ron D
Perk is essential for translational regulation and cell survival during the unfolded protein response.
Molecular cell 2000;5(5):897-904.
2000: Adélaïde J; Chaffanet M; Mozziconacci M J; Popovici C; Conte N; Fernandez F; Sobol H; Jacquemier J; Pébusque M; Ron D; Lafage-Pochitaloff M; Birnbaum D
Translocation and coamplification of loci from chromosome arms 8p and 11q in the MDA-MB-175 mammary carcinoma cell line.
International journal of oncology 2000;16(4):683-8.
2000: Kuroda M; Sok J; Webb L; Baechtold H; Urano F; Yin Y; Chung P; de Rooij D G; Akhmedov A; Ashley T; Ron D
Male sterility and enhanced radiation sensitivity in TLS(-/-) mice.
The EMBO journal 2000;19(3):453-62.
2000: Urano F; Wang X; Bertolotti A; Zhang Y; Chung P; Harding H P; Ron D
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1.
Science (New York, N.Y.) 2000;287(5453):664-6.
1999: Berman B; Ostrovsky O; Shlissel M; Lang T; Regan D; Vlodavsky I; Ishai-Michaeli R; Ron D
Similarities and differences between the effects of heparin and glypican-1 on the bioactivity of acidic fibroblast growth factor and the keratinocyte growth factor.
The Journal of biological chemistry 1999;274(51):36132-8.
1999: Maytin E V; Lin J C; Krishnamurthy R; Batchvarova N; Ron D; Mitchell P J; Habener J F
Keratin 10 gene expression during differentiation of mouse epidermis requires transcription factors C/EBP and AP-2.
Developmental biology 1999;216(1):164-81.
1999: Sher I; Weizman A; Lubinsky-Mink S; Lang T; Adir N; Schomburg D; Ron D
Mutations uncouple human fibroblast growth factor (FGF)-7 biological activity and receptor binding and support broad specificity in the secondary receptor binding site of FGFs.
The Journal of biological chemistry 1999;274(49):35016-22.
1999: Baechtold H; Kuroda M; Sok J; Ron D; Lopez B S; Akhmedov A T
Human 75-kDa DNA-pairing protein is identical to the pro-oncoprotein TLS/FUS and is able to promote D-loop formation.
The Journal of biological chemistry 1999;274(48):34337-42.
1999: Wang X Z; Jolicoeur E M; Conte N; Chaffanet M; Zhang Y; Mozziconacci M J; Feiner H; Birnbaum D; Pébusque M J; Ron D
gamma-heregulin is the product of a chromosomal translocation fusing the DOC4 and HGL/NRG1 genes in the MDA-MB-175 breast cancer cell line.
Oncogene 1999;18(41):5718-21.
1999: Kuroda M; Wang X; Sok J; Yin Y; Chung P; Giannotti J W; Jacobs K A; Fitz L J; Murtha-Riel P; Turner K J; Ron D
Induction of a secreted protein by the myxoid liposarcoma oncogene.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(9):5025-30.
1999: Jousse C; Bruhat A; Harding H P; Ferrara M; Ron D; Fafournoux P
Amino acid limitation regulates CHOP expression through a specific pathway independent of the unfolded protein response.
FEBS letters 1999;448(2-3):211-6.
1999: Gengrinovitch S; Berman B; David G; Witte L; Neufeld G; Ron D
Glypican-1 is a VEGF165 binding proteoglycan that acts as an extracellular chaperone for VEGF165.
The Journal of biological chemistry 1999;274(16):10816-22.
1999: Harding H P; Zhang Y; Ron D
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase.
Nature 1999;397(6716):271-4.
1999: Sok J; Wang X Z; Batchvarova N; Kuroda M; Harding H; Ron D
CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI.
Molecular and cellular biology 1999;19(1):495-504.
1998: Wang X Z; Harding H P; Zhang Y; Jolicoeur E M; Kuroda M; Ron D
Cloning of mammalian Ire1 reveals diversity in the ER stress responses.
The EMBO journal 1998;17(19):5708-17.
1998: Wang X Z; Kuroda M; Sok J; Batchvarova N; Kimmel R; Chung P; Zinszner H; Ron D
Identification of novel stress-induced genes downstream of chop.
The EMBO journal 1998;17(13):3619-30.
1998: Zinszner H; Kuroda M; Wang X; Batchvarova N; Lightfoot R T; Remotti H; Stevens J L; Ron D
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum.
Genes & development 1998;12(7):982-95.
1998: Powers C A; Mathur M; Raaka B M; Ron D; Samuels H H
TLS (translocated-in-liposarcoma) is a high-affinity interactor for steroid, thyroid hormone, and retinoid receptors.
Molecular endocrinology (Baltimore, Md.) 1998;12(1):4-18.
1997: Zinszner H; Sok J; Immanuel D; Yin Y; Ron D
TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling.
Journal of cell science 1997;110 ( Pt 15)():1741-50.
1997: Bruhat A; Jousse C; Wang X Z; Ron D; Ferrara M; Fafournoux P
Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post-transcriptional levels.
The Journal of biological chemistry 1997;272(28):17588-93.
1997: Bonneh-Barkay D; Shlissel M; Berman B; Shaoul E; Admon A; Vlodavsky I; Carey D J; Asundi V K; Reich-Slotky R; Ron D
Identification of glypican as a dual modulator of the biological activity of fibroblast growth factors.
The Journal of biological chemistry 1997;272(19):12415-21.
1997: Zinszner H; Immanuel D; Yin Y; Liang F X; Ron D
A topogenic role for the oncogenic N-terminus of TLS: nucleolar localization when transcription is inhibited.
Oncogene 1997;14(4):451-61.
1997: Ron D
TLS-CHOP and the role of RNA-binding proteins in oncogenic transformation.
Current topics in microbiology and immunology 1997;220():131-42.
1996: Wang X Z; Lawson B; Brewer J W; Zinszner H; Sanjay A; Mi L J; Boorstein R; Kreibich G; Hendershot L M; Ron D
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).
Molecular and cellular biology 1996;16(8):4273-80.
1996: Wang X Z; Ron D
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase.
Science (New York, N.Y.) 1996;272(5266):1347-9.
1996: Ubeda M; Wang X Z; Zinszner H; Wu I; Habener J F; Ron D
Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element.
Molecular and cellular biology 1996;16(4):1479-89.
1995: Reich-Slotky R; Shaoul E; Berman B; Graziani G; Ron D
Chimeric molecules between keratinocyte growth factor and basic fibroblast growth factor define domains that confer receptor binding specificities.
The Journal of biological chemistry 1995;270(50):29813-8.
1995: Batchvarova N; Wang X Z; Ron D
Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153).
The EMBO journal 1995;14(19):4654-61.
1995: Immanuel D; Zinszner H; Ron D
Association of SARFH (sarcoma-associated RNA-binding fly homolog) with regions of chromatin transcribed by RNA polymerase II.
Molecular and cellular biology 1995;15(8):4562-71.
1995: Rubin J S; Bottaro D P; Chedid M; Miki T; Ron D; Cheon G; Taylor W G; Fortney E; Sakata H; Finch P W
Keratinocyte growth factor.
Cell biology international 1995;19(5):399-411.
1995: Shaoul E; Reich-Slotky R; Berman B; Ron D
Fibroblast growth factor receptors display both common and distinct signaling pathways.
Oncogene 1995;10(8):1553-61.
1995: Rubin J S; Bottaro D P; Chedid M; Miki T; Ron D; Cunha G R; Finch P W
Keratinocyte growth factor as a cytokine that mediates mesenchymal-epithelial interaction.
EXS 1995;74():191-214.
1994: Reich-Slotky R; Bonneh-Barkay D; Shaoul E; Bluma B; Svahn C M; Ron D
Differential effect of cell-associated heparan sulfates on the binding of keratinocyte growth factor (KGF) and acidic fibroblast growth factor to the KGF receptor.
The Journal of biological chemistry 1994;269(51):32279-85.
1994: Zinszner H; Albalat R; Ron D
A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP.
Genes & development 1994;8(21):2513-26.
1994: Ron D
Inducible growth arrest: new mechanistic insights.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):1985-6.
1993: Crozat A; Aman P; Mandahl N; Ron D
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma.
Nature 1993;363(6430):640-4.
1993: Vallejo M; Ron D; Miller C P; Habener J F
C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4679-83.
1993: McGehee R E; Ron D; Brasier A R; Habener J F
Differentiation-specific element: a cis-acting developmental switch required for the sustained transcriptional expression of the angiotensinogen gene during hormonal-induced differentiation of 3T3-L1 fibroblasts to adipocytes.
Molecular endocrinology (Baltimore, Md.) 1993;7(4):551-60.
1993: Ron D; Reich R; Chedid M; Lengel C; Cohen O E; Chan A M; Neufeld G; Miki T; Tronick S R
Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factor.
The Journal of biological chemistry 1993;268(8):5388-94.
1993: Ron D; Bottaro D P; Finch P W; Morris D; Rubin J S; Aaronson S A
Expression of biologically active recombinant keratinocyte growth factor. Structure/function analysis of amino-terminal truncation mutants.
The Journal of biological chemistry 1993;268(4):2984-8.
1992: Ron D; Habener J F
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.
Genes & development 1992;6(3):439-53.
1992: Ron D; Brasier A R; McGehee R E; Habener J F
Tumor necrosis factor-induced reversal of adipocytic phenotype of 3T3-L1 cells is preceded by a loss of nuclear CCAAT/enhancer binding protein (C/EBP).
The Journal of clinical investigation 1992;89(1):223-33.
1991: Eisemann A; Ahn J A; Graziani G; Tronick S R; Ron D
Alternative splicing generates at least five different isoforms of the human basic-FGF receptor.
Oncogene 1991;6(7):1195-202.
1991: Ron D; Brasier A R; Habener J F
Angiotensinogen gene-inducible enhancer-binding protein 1, a member of a new family of large nuclear proteins that recognize nuclear factor kappa B-binding sites through a zinc finger motif.
Molecular and cellular biology 1991;11(5):2887-95.
1991: Ron D; Zannini M; Lewis M; Wickner R B; Hunt L T; Graziani G; Tronick S R; Aaronson S A; Eva A
A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr.
The New biologist 1991;3(4):372-9.
1991: Miki T; Fleming T P; Bottaro D P; Rubin J S; Ron D; Aaronson S A
Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop.
Science (New York, N.Y.) 1991;251(4989):72-5.
1991: Graziani G; Ron D; Srivastava S; Eva A
Expression of the human dbl-oncogene and proto-oncogene products in insect cells using a baculovirus vector.
Annali dell'Istituto superiore di sanità 1991;27(1):115-21.
1991: Aaronson S A; Bottaro D P; Miki T; Ron D; Finch P W; Fleming T P; Ahn J; Taylor W G; Rubin J S
Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity.
Annals of the New York Academy of Sciences 1991;638():62-77.
1990: Brasier A R; Ron D; Tate J E; Habener J F
A family of constitutive C/EBP-like DNA binding proteins attenuate the IL-1 alpha induced, NF kappa B mediated trans-activation of the angiotensinogen gene acute-phase response element.
The EMBO journal 1990;9(12):3933-44.
1990: Ron D; Brasier A R; Habener J F
Transcriptional regulation of hepatic angiotensinogen gene expression by the acute-phase response.
Molecular and cellular endocrinology 1990;74(3):C97-104.
1990: Brasier A R; Ron D; Tate J E; Habener J F
Synergistic enhansons located within an acute phase responsive enhancer modulate glucocorticoid induction of angiotensinogen gene transcription.
Molecular endocrinology (Baltimore, Md.) 1990;4(12):1921-33.
1990: Ron D; Brasier A R; Wright K A; Habener J F
The permissive role of glucocorticoids on interleukin-1 stimulation of angiotensinogen gene transcription is mediated by an interaction between inducible enhancers.
Molecular and cellular biology 1990;10(8):4389-95.
1990: Bottaro D P; Rubin J S; Ron D; Finch P W; Florio C; Aaronson S A
Characterization of the receptor for keratinocyte growth factor. Evidence for multiple fibroblast growth factor receptors.
The Journal of biological chemistry 1990;265(22):12767-70.
1990: Ron D; Brasier A R; Wright K A; Tate J E; Habener J F
An inducible 50-kilodalton NF kappa B-like protein and a constitutive protein both bind the acute-phase response element of the angiotensinogen gene.
Molecular and cellular biology 1990;10(3):1023-32.
1989: Ron D; Graziani G; Aaronson S A; Eva A
The N-terminal region of proto-dbl down regulates its transforming activity.
Oncogene 1989;4(9):1067-72.
1989: Finch P W; Rubin J S; Miki T; Ron D; Aaronson S A
Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth.
Science (New York, N.Y.) 1989;245(4919):752-5.
1989: Vecchio G; Cavazzana A O; Triche T J; Ron D; Reynolds C P; Eva A
Expression of the dbl proto-oncogene in Ewing's sarcomas.
Oncogene 1989;4(7):897-900.
1989: Graziani G; Ron D; Eva A; Srivastava S K
The human dbl-proto-oncogene product is a cytoplasmic phosphoprotein which is associated with the cytoskeletal matrix.
Oncogene 1989;4(7):823-9.
1989: Brasier A R; Tate J E; Ron D; Habener J F
Multiple cis-acting DNA regulatory elements mediate hepatic angiotensinogen gene expression.
Molecular endocrinology (Baltimore, Md.) 1989;3(6):1022-34.
1989: Ruggiero M; Srivastava S K; Fleming T P; Ron D; Eva A
NIH3T3 fibroblasts transformed by the dbl oncogene show altered expression of bradykinin receptors: effect on inositol lipid turnover.
Oncogene 1989;4(6):767-71.
1988: Ron D; Tronick S R; Aaronson S A; Eva A
Molecular cloning and characterization of the human dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells.
The EMBO journal 1988;7(8):2465-73.
1987: Eva A; Vecchio G; Diamond M; Tronick S R; Ron D; Cooper G M; Aaronson S A
Independently activated dbl oncogenes exhibit similar yet distinct structural alterations.
Oncogene 1987;1(4):355-60.

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