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Ze'ev Ronai

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Kim Hyungsoo; Ronai Ze'ev
Tricking melanoma to self-digest: a deal of a meal!
Katiyar Samiksha; Liu Enbo; Knutzen Christine A; Lang Elizabeth S; Lombardo Christian R; Sankar Sabita; Toth Julia I; Petroski Matthew D; Ronai Ze'ev; Chiang Gary G
REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase.
Tcherpakov Marianna; Delaunay Agnes; Toth Julia; Kadoya Takayuki; Petroski Matthew D; Ronai Ze'ev A
Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP).

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All Publications

2009: Kim Hyungsoo; Ronai Ze'ev
Tricking melanoma to self-digest: a deal of a meal!
Cancer cell 2009;16(2):83-4.
2009: Katiyar Samiksha; Liu Enbo; Knutzen Christine A; Lang Elizabeth S; Lombardo Christian R; Sankar Sabita; Toth Julia I; Petroski Matthew D; Ronai Ze'ev; Chiang Gary G
REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase.
EMBO reports 2009;10(8):866-72.
2009: Tcherpakov Marianna; Delaunay Agnes; Toth Julia; Kadoya Takayuki; Petroski Matthew D; Ronai Ze'ev A
Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP).
The Journal of biological chemistry 2009;284(18):12099-109.
2009: Nakayama Koh; Qi Jianfei; Ronai Ze'ev
The ubiquitin ligase Siah2 and the hypoxia response.
Molecular cancer research : MCR 2009;7(4):443-51.
2009: Gaitonde Supriya; De Surya K; Tcherpakov Marianna; Dewing Antimone; Yuan Hongbin; Riel-Mehan Megan; Krajewski Stan; Robertson Gavin; Pellecchia Maurizio; Ronai Ze'ev
BI-69A11-mediated inhibition of AKT leads to effective regression of xenograft melanoma.
Pigment cell & melanoma research 2009;22(2):187-95.
2009: Xiong Hui; Wang Danling; Chen Linan; Choo Yeun Su; Ma Hong; Tang Chengyuan; Xia Kun; Jiang Wei; Ronai Ze'ev; Zhuang Xiaoxi; Zhang Zhuohua
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation.
The Journal of clinical investigation 2009;119(3):650-60.
2008: Tcherpakov Marianna; Broday Limor; Delaunay Agnes; Kadoya Takayuki; Khurana Ashwani; Erdjument-Bromage Hediye; Tempst Paul; Qiu Xiao-Bo; DeMartino George N; Ronai Ze'ev
JAMP optimizes ERAD to protect cells from unfolded proteins.
Molecular biology of the cell 2008;19(11):5019-28.
2008: Qi Jianfei; Nakayama Koh; Gaitonde Supriya; Goydos James S; Krajewski Stan; Eroshkin Alexey; Bar-Sagi Dafna; Bowtell David; Ronai Ze'ev
The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(43):16713-8.
2008: Bhoumik Anindita; Ronai Ze'ev
ATF2: a transcription factor that elicits oncogenic or tumor suppressor activities.
Cell cycle (Georgetown, Tex.) 2008;7(15):2341-5.
2008: Bhoumik Anindita; Singha Netai; O'Connell Matthew J; Ronai Ze'ev A
Regulation of TIP60 by ATF2 modulates ATM activation.
The Journal of biological chemistry 2008;283(25):17605-14.
2008: Bhoumik Anindita; Ronai Ze'ev
Melanoma initiating cells - easy as ABC?
Pigment cell & melanoma research 2008;21(2):111-2.
2008: Yano Hajime; Kobayashi Itaru; Onodera Yasuhito; Luton Frédéric; Franco Michel; Mazaki Yuichi; Hashimoto Shigeru; Iwai Kazuhiro; Ronai Ze'ev; Sabe Hisataka
Fbx8 makes Arf6 refractory to function via ubiquitination.
Molecular biology of the cell 2008;19(3):822-32.
2008: Lopez-Bergami Pablo; Fitchman Boris; Ronai Ze'ev
Understanding signaling cascades in melanoma.
Photochemistry and photobiology 2008;84(2):289-306.
2008: Bhoumik Anindita; Fichtman Boris; Derossi Charles; Breitwieser Wolfgang; Kluger Harriet M; Davis Sean; Subtil Antonio; Meltzer Paul; Krajewski Stan; Jones Nic; Ronai Ze'ev
Suppressor role of activating transcription factor 2 (ATF2) in skin cancer.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(5):1674-9.
2008: Delaunay Agnès; Bromberg Kenneth D; Hayashi Yukiko; Mirabella Massimiliano; Burch Denise; Kirkwood Brian; Serra Carlo; Malicdan May C; Mizisin Andrew P; Morosetti Roberta; Broccolini Aldobrando; Guo Ling T; Jones Stephen N; Lira Sergio A; Puri Pier Lorenzo; Shelton G Diane; Ronai Ze'ev
The ER-bound RING finger protein 5 (RNF5/RMA1) causes degenerative myopathy in transgenic mice and is deregulated in inclusion body myositis.
PloS one 2008;3(2):e1609.
2008: Lopez-Bergami Pablo; Ronai Ze'ev
Requirements for PKC-augmented JNK activation by MKK4/7.
The international journal of biochemistry & cell biology 2008;40(5):1055-64.
2007: Herlyn Meenhard; Halaban Ruth; Ronai Ze'ev; Schuchter Lynn; Berwick Marianne; Pinkel Daniel
Roadmap for new opportunities in melanoma research.
Seminars in oncology 2007;34(6):566-76.
2007: Bhoumik Anindita; Lopez-Bergami Pablo; Ronai Ze'ev
ATF2 on the double - activating transcription factor and DNA damage response protein.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2007;20(6):498-506.
2007: Abbas Sabiha; Bhoumik Anindita; Dahl Russell; Vasile Stefan; Krajewski Stan; Cosford Nicholas D P; Ronai Ze'ev A
Preclinical studies of celastrol and acetyl isogambogic acid in melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(22 Pt 1):6769-78.
2007: Broday Limor; Hauser Craig A; Kolotuev Irina; Ronai Ze'ev
Muscle-epidermis interactions affect exoskeleton patterning in Caenorhabditis elegans.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(11):3129-36.
2007: Bromberg Kenneth D; Kluger Harriet M; Delaunay Agnes; Abbas Sabiha; DiVito Kyle A; Krajewski Stan; Ronai Ze'ev
Increased expression of the E3 ubiquitin ligase RNF5 is associated with decreased survival in breast cancer.
Cancer research 2007;67(17):8172-9.
2007: Mikolajczyk Jowita; Drag Marcin; Békés Miklós; Cao John T; Ronai Ze'ev; Salvesen Guy S
Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs.
The Journal of biological chemistry 2007;282(36):26217-24.
2007: Pimienta Genaro; Ficarro Scott B; Gutierrez Gustavo J; Bhoumik Anindita; Peters Eric C; Ronai Ze'ev; Pascual Jaime
Autophosphorylation properties of inactive and active JNK2.
Cell cycle (Georgetown, Tex.) 2007;6(14):1762-71.
2007: Gaitonde Supriya; Ronai Ze'ev
A darker side to p53.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2007;20(3):148-9.
2007: Lopez-Bergami Pablo; Huang Conway; Goydos James S; Yip Dana; Bar-Eli Menashe; Herlyn Meenhard; Smalley Keiran S M; Mahale Alka; Eroshkin Alexey; Aaronson Stuart; Ronai Ze'ev
Rewired ERK-JNK signaling pathways in melanoma.
Cancer cell 2007;11(5):447-60.
2007: Fukushima Toru; Matsuzawa Shu-ichi; Kress Christina L; Bruey Jean Marie; Krajewska Maryla; Lefebvre Sophie; Zapata Juan M; Ronai Ze'ev; Reed John C
Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6371-6.
2007: Laine A; Ronai Z
Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1.
Oncogene 2007;26(10):1477-83.
2007: Nakayama Koh; Gazdoiu Stefan; Abraham Robert; Pan Zhen-Qiang; Ronai Ze'ev
Hypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2.
The Biochemical journal 2007;401(1):217-26.
2006: Laine Aaron; Topisirovic Ivan; Zhai Dayong; Reed John C; Borden Katherine L B; Ronai Ze'ev
Regulation of p53 localization and activity by Ubc13.
Molecular and cellular biology 2006;26(23):8901-13.
2006: Hirano Yuko; Ronai Ze'ev
A new function for p53 ubiquitination.
Cell 2006;127(4):675-7.
2006: Khurana Ashwani; Nakayama Koh; Williams Scott; Davis Roger J; Mustelin Tomas; Ronai Ze'ev
Regulation of the ring finger E3 ligase Siah2 by p38 MAPK.
The Journal of biological chemistry 2006;281(46):35316-26.
2006: Cerignoli Fabio; Rahmouni Souad; Ronai Ze'ev; Mustelin Tomas
Regulation of MAP kinases by the VHR dual-specific phosphatase: implications for cell growth and differentiation.
Cell cycle (Georgetown, Tex.) 2006;5(19):2210-5.
2006: Gutierrez Gustavo J; Vögtlin Andrea; Castro Ana; Ferby Ingvar; Salvagiotto Giorgia; Ronai Ze'ev; Lorca Thierry; Nebreda Angel R
Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation.
Nature cell biology 2006;8(10):1084-94.
2006: Nakayama Koh; Ronai Ze'ev
[Ubiquitin system in hypoxia response]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2006;51(10 Suppl):1309-15.
2006: Ronai Ze'ev
Balancing Mdm2 - a Daxx-HAUSP matter.
Nature cell biology 2006;8(8):790-1.
2006: Gutierrez Gustavo J; Ronai Ze'ev
Ubiquitin and SUMO systems in the regulation of mitotic checkpoints.
Trends in biochemical sciences 2006;31(6):324-32.
2006: Fukushima Toru; Zapata Juan M; Singha Netai C; Thomas Michael; Kress Christina L; Krajewska Maryla; Krajewski Stan; Ronai Ze'ev; Reed John C; Matsuzawa Shu-Ichi
Critical function for SIP, a ubiquitin E3 ligase component of the beta-catenin degradation pathway, for thymocyte development and G1 checkpoint.
Immunity 2006;24(1):29-39.
2006: Zhang Weizhou; Zong Cong S; Hermanto Ulrich; Lopez-Bergami Pablo; Ronai Ze'ev; Wang Lu-Hai
RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth.
Molecular and cellular biology 2006;26(2):413-24.
2006: Ivanov Vladimir N; Ronai Ze'ev; Hei Tom K
Opposite roles of FAP-1 and dynamin in the regulation of Fas (CD95) translocation to the cell surface and susceptibility to Fas ligand-mediated apoptosis.
The Journal of biological chemistry 2006;281(3):1840-52.
2005: Kadoya Takayuki; Khurana Ashwani; Tcherpakov Marianna; Bromberg Kenneth D; Didier Christine; Broday Limor; Asahara Toshimasa; Bhoumik Anindita; Ronai Ze'ev
JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity.
Molecular and cellular biology 2005;25(19):8619-30.
2005: López-Bergami Pablo; Habelhah Hasem; Bhoumik Anindita; Zhang Weizhou; Wang Lu-Hai; Ronai Ze'ev
RACK1 mediates activation of JNK by protein kinase C [corrected]
Molecular cell 2005;19(3):309-20.
2005: Bhoumik Anindita; Takahashi Shoichi; Breitweiser Wolfgang; Shiloh Yosef; Jones Nic; Ronai Ze'ev
ATM-dependent phosphorylation of ATF2 is required for the DNA damage response.
Molecular cell 2005;18(5):577-87.
2005: Laine Aaron; Ronai Ze'ev
Ubiquitin chains in the ladder of MAPK signaling.
Science's STKE : signal transduction knowledge environment 2005;2005(281):re5.
2005: Elias Bertha; Laine Aaron; Ronai Ze'ev
Phosphorylation of MdmX by CDK2/Cdc2(p34) is required for nuclear export of Mdm2.
Oncogene 2005;24(15):2574-9.
2004: Habelhah Hasem; Laine Aaron; Erdjument-Bromage Hediye; Tempst Paul; Gershwin M Eric; Bowtell David D L; Ronai Ze'ev
Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah.
The Journal of biological chemistry 2004;279(51):53782-8.
2004: Bhoumik Anindita; Gangi Lisa; Ronai Ze'ev
Inhibition of melanoma growth and metastasis by ATF2-derived peptides.
Cancer research 2004;64(22):8222-30.
2004: Nakayama Koh; Ronai Ze'ev
Siah: new players in the cellular response to hypoxia.
Cell cycle (Georgetown, Tex.) 2004;3(11):1345-7.
2004: Broday Limor; Kolotuev Irina; Didier Christine; Bhoumik Anindita; Gupta Bhagwati P; Sternberg Paul W; Podbilewicz Benjamin; Ronai Ze'ev
The small ubiquitin-like modifier (SUMO) is required for gonadal and uterine-vulval morphogenesis in Caenorhabditis elegans.
Genes & development 2004;18(19):2380-91.
2004: Ronai Ze'ev
JNKing Revealed.
Molecular cell 2004;15(6):843-4.
2004: Broday Limor; Kolotuev Irina; Didier Christine; Bhoumik Anindita; Podbilewicz Benjamin; Ronai Ze'ev
The LIM domain protein UNC-95 is required for the assembly of muscle attachment structures and is regulated by the RING finger protein RNF-5 in C. elegans.
The Journal of cell biology 2004;165(6):857-67.
2004: Nakayama Koh; Frew Ian J; Hagensen Mette; Skals Marianne; Habelhah Hasem; Bhoumik Anindita; Kadoya Takayuki; Erdjument-Bromage Hediye; Tempst Paul; Frappell Peter B; Bowtell David D; Ronai Ze'ev
Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia.
Cell 2004;117(7):941-52.
2004: Yang Shilin; Yang Yi; Raycraft John; Zhang Hongtao; Kanan Sandra; Guo Yajun; Ronai Ze'ev; Hellstrom Ingegerd; Hellstrom Karl Erik
Melanoma cells transfected to express CD83 induce antitumor immunity that can be increased by also engaging CD137.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4990-5.
2004: Bhoumik Anindita; Jones Nic; Ronai Ze'ev
Transcriptional switch by activating transcription factor 2-derived peptide sensitizes melanoma cells to apoptosis and inhibits their tumorigenicity.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4222-7.
2004: Alarcon-Vargas Dania; Ronai Ze'ev
c-Jun-NH2 kinase (JNK) contributes to the regulation of c-Myc protein stability.
The Journal of biological chemistry 2004;279(6):5008-16.
2004: Mujtaba Shiraz; He Yan; Zeng Lei; Yan Sherry; Plotnikova Olga; Sachchidanand; Sanchez Roberto; Zeleznik-Le Nancy J; Ronai Ze'ev; Zhou Ming-Ming
Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.
Molecular cell 2004;13(2):251-63.
2004: Habelhah Hasem; Takahashi Shoichi; Cho Ssang-Goo; Kadoya Takayuki; Watanabe Toshiki; Ronai Ze'ev
Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB.
The EMBO journal 2004;23(2):322-32.
2004: Pak Brian J; Lee Jane; Thai Boun L; Fuchs Serge Y; Shaked Yuval; Ronai Ze'ev; Kerbel Robert S; Ben-David Yaacov
Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase.
Oncogene 2004;23(1):30-8.
2003: Berger Aaron J; Kluger Harriet M; Li Ning; Kielhorn Eric; Halaban Ruth; Ronai Ze'ev; Rimm David L
Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival.
Cancer research 2003;63(23):8103-7.
2003: Didier Christine; Broday Limor; Bhoumik Anindita; Israeli Sharon; Takahashi Shoichi; Nakayama Koh; Thomas Sheila M; Turner Christopher E; Henderson Scott; Sabe Hisataka; Ronai Ze'ev
RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization.
Molecular and cellular biology 2003;23(15):5331-45.
2003: Dong Jianli; Phelps Robert G; Qiao Rui; Yao Shen; Benard Outhiriaradjou; Ronai Zeev; Aaronson Stuart A
BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma.
Cancer research 2003;63(14):3883-5.
2003: Krasilnikov Mikhail; Ivanov Vladimir N; Dong Jinali; Ronai Ze'ev
ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis.
Oncogene 2003;22(26):4092-101.
2003: Ivanov Vladimir N; Bhoumik Anindita; Ronai Ze'ev
Death receptors and melanoma resistance to apoptosis.
Oncogene 2003;22(20):3152-61.
2003: Ivanov Vladimir N; Lopez Bergami Pablo; Maulit Gabriel; Sato Taka-Aki; Sassoon David; Ronai Ze'ev
FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface.
Molecular and cellular biology 2003;23(10):3623-35.
2003: Pluquet Olivier; North Sophie; Bhoumik Anindita; Dimas Konstantinos; Ronai Ze'ev; Hainaut Pierre
The cytoprotective aminothiol WR1065 activates p53 through a non-genotoxic signaling pathway involving c-Jun N-terminal kinase.
The Journal of biological chemistry 2003;278(14):11879-87.
2003: Vargas Dania Alarcon; Takahashi Shoichi; Ronai Ze'ev
Mdm2: A regulator of cell growth and death.
Advances in cancer research 2003;89():1-34.
2002: Habelhah Hasem; Frew Ian J; Laine Aaron; Janes Peter W; Relaix Frederic; Sassoon David; Bowtell David D L; Ronai Ze'ev
Stress-induced decrease in TRAF2 stability is mediated by Siah2.
The EMBO journal 2002;21(21):5756-65.
2002: Zacchi Paola; Gostissa Monica; Uchida Takafumi; Salvagno Clio; Avolio Fabio; Volinia Stefano; Ronai Ze'ev; Blandino Giovanni; Schneider Claudio; Del Sal Giannino
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults.
Nature 2002;419(6909):853-7.
2002: Bhoumik Anindita; Huang Tian-Gui; Ivanov Vladimir; Gangi Lisa; Qiao Rui F; Woo Savio L C; Chen Shu-Hsia; Ronai Ze'ev
An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis.
The Journal of clinical investigation 2002;110(5):643-50.
2002: Fuchs Serge Y; Lee Chee-Gun; Pan Zhen-Qianq; Ronai Ze'ev
SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.
Cell 2002;110(4):531.
2002: Alarcon-Vargas Dania; Tansey William P; Ronai Ze'ev
Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127-189 of c-myc.
Oncogene 2002;21(28):4384-91.
2002: Alarcon-Vargas Dania; Ronai Ze'ev
SUMO in cancer--wrestlers wanted.
Cancer biology & therapy 2002;1(3):237-42.
2002: Alarcon-Vargas Dania; Ronai Ze'ev
p53-Mdm2--the affair that never ends.
Carcinogenesis 2002;23(4):541-7.
2002: Ivanov Vladimir N; Krasilnikov Mikhail; Ronai Ze'ev
Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.
The Journal of biological chemistry 2002;277(7):4932-44.
2001: Cho S G; Bhoumik A; Broday L; Ivanov V; Rosenstein B; Ronai Z
TIP49b, a regulator of activating transcription factor 2 response to stress and DNA damage.
Molecular and cellular biology 2001;21(24):8398-413.
2001: Buschmann T; Lerner D; Lee C G; Ronai Z
The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9.
The Journal of biological chemistry 2001;276(44):40389-95.
2001: Ruscoe J E; Rosario L A; Wang T; Gaté L; Arifoglu P; Wolf C R; Henderson C J; Ronai Z; Tew K D
Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways.
The Journal of pharmacology and experimental therapeutics 2001;298(1):339-45.
2001: Spiegelman V S; Stavropoulos P; Latres E; Pagano M; Ronai Z; Slaga T J; Fuchs S Y
Induction of beta-transducin repeat-containing protein by JNK signaling and its role in the activation of NF-kappaB.
The Journal of biological chemistry 2001;276(29):27152-8.
2001: Minamoto T; Buschmann T; Habelhah H; Matusevich E; Tahara H; Boerresen-Dale A L; Harris C; Sidransky D; Ronai Z
Distinct pattern of p53 phosphorylation in human tumors.
Oncogene 2001;20(26):3341-7.
2001: Wang T; Arifoglu P; Ronai Z; Tew K D
Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus.
The Journal of biological chemistry 2001;276(24):20999-1003.
2001: Maya R; Balass M; Kim S T; Shkedy D; Leal J F; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan M B; Katzir E; Oren M
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
Genes & development 2001;15(9):1067-77.
2001: Habelhah H; Shah K; Huang L; Burlingame A L; Shokat K M; Ronai Z
Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue.
The Journal of biological chemistry 2001;276(21):18090-5.
2001: Ivanov V N; Fodstad O; Ronai Z
Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFalpha and suppression of NF-kappaB activities.
Oncogene 2001;20(18):2243-53.
2001: Buschmann T; Potapova O; Bar-Shira A; Ivanov V N; Fuchs S Y; Henderson S; Fried V A; Minamoto T; Alarcon-Vargas D; Pincus M R; Gaarde W A; Holbrook N J; Shiloh Y; Ronai Z
Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.
Molecular and cellular biology 2001;21(8):2743-54.
2001: Buschmann T; Lin Y; Aithmitti N; Fuchs S Y; Lu H; Resnick-Silverman L; Manfredi J J; Ronai Z; Wu X
Stabilization and activation of p53 by the coactivator protein TAFII31.
The Journal of biological chemistry 2001;276(17):13852-7.
2001: Ivanov V N; Bhoumik A; Krasilnikov M; Raz R; Owen-Schaub L B; Levy D; Horvath C M; Ronai Z
Cooperation between STAT3 and c-jun suppresses Fas transcription.
Molecular cell 2001;7(3):517-28.
2001: Habelhah H; Shah K; Huang L; Ostareck-Lederer A; Burlingame A L; Shokat K M; Hentze M W; Ronai Z
ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation.
Nature cell biology 2001;3(3):325-30.
2001: Bhoumik A; Ivanov V; Ronai Z
Activating transcription factor 2-derived peptides alter resistance of human tumor cell lines to ultraviolet irradiation and chemical treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(2):331-42.
2001: Davis W; Ronai Z; Tew K D
Cellular thiols and reactive oxygen species in drug-induced apoptosis.
The Journal of pharmacology and experimental therapeutics 2001;296(1):1-6.
2000: Yin Z; Ivanov V N; Habelhah H; Tew K; Ronai Z
Glutathione S-transferase p elicits protection against H2O2-induced cell death via coordinated regulation of stress kinases.
Cancer research 2000;60(15):4053-7.
2000: Buschmann T; Fuchs S Y; Lee C G; Pan Z Q; Ronai Z
SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.
Cell 2000;101(7):753-62.
2000: Ivanov V N; Ronai Z
p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression.
Oncogene 2000;19(26):3003-12.
2000: Buschmann T; Yin Z; Bhoumik A; Ronai Z
Amino-terminal-derived JNK fragment alters expression and activity of c-Jun, ATF2, and p53 and increases H2O2-induced cell death.
The Journal of biological chemistry 2000;275(22):16590-6.
2000: Spiegelman V S; Slaga T J; Pagano M; Minamoto T; Ronai Z; Fuchs S Y
Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor.
Molecular cell 2000;5(5):877-82.
2000: Fuchs S Y; Tappin I; Ronai Z
Stability of the ATF2 transcription factor is regulated by phosphorylation and dephosphorylation.
The Journal of biological chemistry 2000;275(17):12560-4.
2000: Buschmann T; Adler V; Matusevich E; Fuchs S Y; Ronai Z
p53 phosphorylation and association with murine double minute 2, c-Jun NH2-terminal kinase, p14ARF, and p300/CBP during the cell cycle and after exposure to ultraviolet irradiation.
Cancer research 2000;60(4):896-900.
2000: Ivanov V N; Kehrl J H; Ronai Z
Role of TRAF2/GCK in melanoma sensitivity to UV-induced apoptosis.
Oncogene 2000;19(7):933-42.
2000: Alarcon-Vargas D; Fuchs S Y; Deb S; Ronai Z
p73 transcriptional activity increases upon cooperation between its spliced forms.
Oncogene 2000;19(6):831-5.
2000: Wu K; Fuchs S Y; Chen A; Tan P; Gomez C; Ronai Z; Pan Z Q
The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation.
Molecular and cellular biology 2000;20(4):1382-93.
2000: Villafania A; Anwar K; Amar S; Chie L; Way D; Chung D L; Adler V; Ronai Z; Brandt-Rauf P W; Yamaizumii Z; Kung H F; Pincus M R
Glutathione-S-Transferase as a selective inhibitor of oncogenic ras-p21-induced mitogenic signaling through blockade of activation of jun by jun-N-terminal kinase.
Annals of clinical and laboratory science 2000;30(1):57-64.
2000: Buschmann T; Minamoto T; Wagle N; Fuchs S Y; Adler V; Mai M; Ronai Z
Analysis of JNK, Mdm2 and p14(ARF) contribution to the regulation of mutant p53 stability.
Journal of molecular biology 2000;295(4):1009-21.
2000: Chie L; Amar S; Kung H F; Lin M C; Chen H; Chung D L; Adler V; Ronai Z; Friedman F K; Robinson R C; Kovac C; Brandt-Rauf P W; Yamaizumi Z; Michl J; Pincus M R
Induction of oocyte maturation by jun-N-terminal kinase (JNK) on the oncogenic ras-p21 pathway is dependent on the raf-MEK signal transduction pathway.
Cancer chemotherapy and pharmacology 2000;45(6):441-9.
1999: Monaco R; Friedman F K; Hyde M J; Chen J M; Manolatus S; Adler V; Ronai Z; Koslosky W; Pincus M R
Identification of a glutathione-S-transferase effector domain for inhibition of jun kinase, by molecular dynamics.
Journal of protein chemistry 1999;18(8):859-66.
1999: Adler V; Yin Z; Tew K D; Ronai Z
Role of redox potential and reactive oxygen species in stress signaling.
Oncogene 1999;18(45):6104-11.
1999: Ivanov V N; Ronai Z
Down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells.
The Journal of biological chemistry 1999;274(20):14079-89.
1999: Fuchs S Y; Ronai Z
Ubiquitination and degradation of ATF2 are dimerization dependent.
Molecular and cellular biology 1999;19(5):3289-98.
1999: Tan P; Fuchs S Y; Chen A; Wu K; Gomez C; Ronai Z; Pan Z Q
Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha.
Molecular cell 1999;3(4):527-33.
1999: Minamoto T; Mai M; Ronai Z
Environmental factors as regulators and effectors of multistep carcinogenesis.
Carcinogenesis 1999;20(4):519-27.
1999: Fuchs S Y; Chen A; Xiong Y; Pan Z Q; Ronai Z
HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin.
Oncogene 1999;18(12):2039-46.
1999: Adler V; Yin Z; Fuchs S Y; Benezra M; Rosario L; Tew K D; Pincus M R; Sardana M; Henderson C J; Wolf C R; Davis R J; Ronai Z
Regulation of JNK signaling by GSTp.
The EMBO journal 1999;18(5):1321-34.
1999: Krasilnikov M; Adler V; Fuchs S Y; Dong Z; Haimovitz-Friedman A; Herlyn M; Ronai Z
Contribution of phosphatidylinositol 3-kinase to radiation resistance in human melanoma cells.
Molecular carcinogenesis 1999;24(1):64-9.
1998: Fuchs S Y; Adler V; Buschmann T; Wu X; Ronai Z
Mdm2 association with p53 targets its ubiquitination.
Oncogene 1998;17(19):2543-7.
1998: Fuchs S Y; Fried V A; Ronai Z
Stress-activated kinases regulate protein stability.
Oncogene 1998;17(11 Reviews):1483-90.
1998: Fuchs S Y; Adler V; Buschmann T; Yin Z; Wu X; Jones S N; Ronai Z
JNK targets p53 ubiquitination and degradation in nonstressed cells.
Genes & development 1998;12(17):2658-63.
1998: Fuchs S Y; Adler V; Pincus M R; Ronai Z
MEKK1/JNK signaling stabilizes and activates p53.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10541-6.
1998: Ronai Z; Yang Y M; Fuchs S Y; Adler V; Sardana M; Herlyn M
ATF2 confers radiation resistance to human melanoma cells.
Oncogene 1998;16(4):523-31.
1997: Fuchs S Y; Xie B; Adler V; Fried V A; Davis R J; Ronai Z
c-Jun NH2-terminal kinases target the ubiquitination of their associated transcription factors.
The Journal of biological chemistry 1997;272(51):32163-8.
1997: Minamoto T; Esumi H; Ochiai A; Belitsky G; Mai M; Sugimura T; Ronai Z
Combined analysis of microsatellite instability and K-ras mutation increases detection incidence of normal samples from colorectal cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(8):1413-7.
1997: Adler V; Pincus M R; Minamoto T; Fuchs S Y; Bluth M J; Brandt-Rauf P W; Friedman F K; Robinson R C; Chen J M; Wang X W; Harris C C; Ronai Z
Conformation-dependent phosphorylation of p53.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1686-91.
1997: Amar S; Glozman A; Chung D; Adler V; Ronai Z; Friedman F K; Robinson R; Brandt-Rauf P; Yamaizumi Z; Pincus M R
Selective inhibition of oncogenic ras-p21 in vivo by agents that block its interaction with jun-N-kinase (JNK) and jun proteins. Implications for the design of selective chemotherapeutic agents.
Cancer chemotherapy and pharmacology 1997;41(1):79-85.
1997: Ronai Z; Minamoto T
Quantitative enriched PCR (QEPCR), a highly sensitive method for detection of K-ras oncogene mutation.
Human mutation 1997;10(4):322-5.
1996: Fuchs S Y; Dolan L; Davis R J; Ronai Z
Phosphorylation-dependent targeting of c-Jun ubiquitination by Jun N-kinase.
Oncogene 1996;13(7):1531-5.
1996: Adler V; Dolan L R; Kim J; Pincus M; Barrett J C; Ronai Z
Changes in jun N-terminal kinase activation by stress during aging of cultured normal human fibroblasts.
Molecular carcinogenesis 1996;17(1):8-12.
1996: Adler V; Polotskaya A; Kim J; Dolan L; Davis R; Pincus M; Ronai Z
Dose rate and mode of exposure are key factors in JNK activation by UV irradiation.
Carcinogenesis 1996;17(9):2073-6.
1996: Adler V; Pincus M R; Posner S; Upadhyaya P; El-Bayoumy K; Ronai Z
Effects of chemopreventive selenium compounds on Jun N-kinase activities.
Carcinogenesis 1996;17(9):1849-54.
1996: Adler V; Pincus M R; Polotskaya A; Montano X; Friedman F K; Ronai Z
Activation of c-Jun-NH2-kinase by UV irradiation is dependent on p21ras.
The Journal of biological chemistry 1996;271(38):23304-9.
1996: Ronai Z; Polotskaya A; Gradia S; Amin S; Hecht S S
Expression of a 32 kDa protein in rat mammary tumors induced by anti-benzo[c]phenanthrene-3,4-diol-1,2-epoxide.
International journal of cancer. Journal international du cancer 1996;67(1):124-8.
1996: Dhar V; Adler V; Lehmann A; Ronai Z
Impaired jun-NH2-terminal kinase activation by ultraviolet irradiation in fibroblasts of patients with Cockayne syndrome complementation group B.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(6):841-6.
1996: Yang Y M; Dolan L R; Ronai Z
Expression of dominant negative CREB reduces resistance to radiation of human melanoma cells.
Oncogene 1996;12(10):2223-33.
1996: Fuchs S Y; Ronai Z
Elevated binding to URE/PEBP2 during the late stages of NNK and benzo[a]pyrene-induced carcinogenesis in A/J mice.
Cancer letters 1996;102(1-2):101-6.
1995: Adler V; Fuchs S Y; Kim J; Kraft A; King M P; Pelling J; Ronai Z
jun-NH2-terminal kinase activation mediated by UV-induced DNA lesions in melanoma and fibroblast cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(11):1437-46.
1995: Adler V; Schaffer A; Kim J; Dolan L; Ronai Z
UV irradiation and heat shock mediate JNK activation via alternate pathways.
The Journal of biological chemistry 1995;270(44):26071-7.
1995: Ronai Z; Tillotson J K; Traganos F; Darzynkiewicz Z; Conaway C C; Upadhyaya P; el-Bayoumy K
Effects of organic and inorganic selenium compounds on rat mammary tumor cells.
International journal of cancer. Journal international du cancer 1995;63(3):428-34.
1995: Adler V; Pincus M R; Brandt-Rauf P W; Ronai Z
Complexes of p21RAS with JUN N-terminal kinase and JUN proteins.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10585-9.
1995: Yang Y M; Ronai Z
Ultraviolet light-responsive element (TGACAACA)-binding proteins in cells of xeroderma pigmentosum patients.
Molecular carcinogenesis 1995;14(2):111-7.
1995: Rutberg S E; Fuchs S Y; Ronai Z
Ultraviolet irradiation and c-jun over-expression regulates replication of polyoma sequences in WOP cells through a PEBP2 binding site.
Biochimica et biophysica acta 1995;1261(1):90-8.
1995: Ronai Z; Minamoto T; Butler R; Tobi M; Luo F Q; Zang E; Esumi H; Sugimura T
Sampling method as a key factor in identifying K-ras oncogene mutations in preneoplastic colorectal lesions.
Cancer detection and prevention 1995;19(6):512-7.
1995: Ronai Z; Tillotson J; Cohen L
Effect of dietary fatty acids on gene expression in breast cells.
Advances in experimental medicine and biology 1995;375():85-95.
1994: Dolan L R; Rutberg S E; Amin S; Emura M; Mohr U; Kraft A; Yokoyama K; Ronai Z
Regulation of c-jun by lung carcinogens in Clara cells of hamsters.
Carcinogenesis 1994;15(12):2789-93.
1994: Ronai Z A; Gradia S; el-Bayoumy K; Amin S; Hecht S S
Contrasting incidence of ras mutations in rat mammary and mouse skin tumors induced by anti-benzo[c]phenanthrene-3,4-diol-1,2-epoxide.
Carcinogenesis 1994;15(10):2113-6.
1994: Rutberg S E; Dolan L R; Ronai Z
PEBP2--a modulator of polyoma DNA replication.
DNA and cell biology 1994;13(8):865-74.
1994: Rutberg S E; Goldstein I M; Yang Y M; Stackpole C W; Ronai Z
Expression and transcriptional activity of AP-1, CRE, and URE binding proteins in B16 mouse melanoma subclones.
Molecular carcinogenesis 1994;10(2):82-7.
1994: Tillotson J K; Upadhyaya P; Ronai Z
Inhibition of thymidine kinase in cultured mammary tumor cells by the chemopreventive organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate.
Carcinogenesis 1994;15(4):607-10.
1994: Ronai Z; Rutberg S; Yang Y M
UV-responsive element (TGACAACA) from rat fibroblasts to human melanomas.
Environmental and molecular mutagenesis 1994;23(3):157-63.
1993: Ronai Z A; Gradia S; Peterson L A; Hecht S S
G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents.
Carcinogenesis 1993;14(11):2419-22.
1993: Rutberg S E; Ronai Z
General purpose lamps induce polyoma DNA replication in H3 cells.
Photochemistry and photobiology 1993;58(2):265-9.
1993: Yang Y M; Rutberg S E; Luo F C; Spratt T E; Halaban R; Ferrone S; Ronai Z
A transcriptional inhibitor induced in human melanoma cells upon ultraviolet irradiation.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(7):595-602.
1993: Ronai Z
Glycolytic enzymes as DNA binding proteins.
The International journal of biochemistry 1993;25(7):1073-6.
1993: Yang Y M; Rutberg S E; Foiles P G; Ronai Z
Expression pattern of proteins that bind to the ultraviolet-responsive element (TGACAACA) in human keratinocytes.
Molecular carcinogenesis 1993;7(1):36-43.
1993: Lee G; Delohery T M; Ronai Z; Brandt-Rauf P W; Pincus M R; Murphy R B; Weinstein I B
A comparison of techniques for introducing macromolecules into living cells.
Cytometry 1993;14(3):265-70.
1992: Chung D L; Joran A; Friedman F; Robinson R; Brandt-Rauf P W; Weinstein I B; Ronai Z; Baskin L; Dykes D C; Murphy R B
Evidence that oocyte maturation induced by an oncogenic ras-p21 protein and insulin is mediated by overlapping yet distinct mechanisms.
Experimental cell research 1992;203(2):329-35.
1992: Rutberg S E; Yang Y M; Ronai Z
Functional role of the ultraviolet light responsive element (URE; TGACAACA) in the transcription and replication of polyoma DNA.
Nucleic acids research 1992;20(16):4305-10.
1992: Foiles P G; Peterson L A; Miglietta L M; Ronai Z
Analysis of mutagenic activity and ability to induce replication of polyoma DNA sequences by different model metabolites of the carcinogenic tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Mutation research 1992;279(2):91-101.
1992: Rutberg S E; Ronai Z
A simple and efficient method for the purification of specific DNA binding proteins.
Nucleic acids research 1992;20(7):1815.
1992: Ronai Z; Robinson R; Rutberg S; Lazarus P; Sardana M
Aldolase-DNA interactions in a SEWA cell system.
Biochimica et biophysica acta 1992;1130(1):20-8.
1992: Ronai Z; Robinson R; Lee G; Okin E; Minarovits J; Wirchubsky Z; Klein G; Weinstein I B
Interaction of SEWA sarcoma cell proteins with the intracisternal A-type particle long terminal repeat DNA sequence.
Molecular carcinogenesis 1992;5(1):81-9.
1991: Kahn S M; Jiang W; Culbertson T A; Weinstein I B; Williams G M; Tomita N; Ronai Z
Rapid and sensitive nonradioactive detection of mutant K-ras genes via 'enriched' PCR amplification.
Oncogene 1991;6(6):1079-83.
1991: Ronai Z; Lau Y Y; Cohen L A
Dietary N-3 fatty acids do not affect induction of Ha-ras mutations in mammary glands of NMU-treated rats.
Molecular carcinogenesis 1991;4(2):120-8.
1990: Ronai Z A; Weinstein I B
Identification of ultraviolet-inducible proteins that bind to a TGACAACA sequence in the polyoma virus regulatory region.
Cancer research 1990;50(17):5374-81.
1990: Robinson R; Ronai Z
Polyoma DNA replication dependent upon growth condition of SEWA sarcoma cells.
Molecular carcinogenesis 1990;3(5):268-72.
1989: Lee G; Ronai Z A; Pincus M R; Brandt-Rauf P W; Murphy R B; Delohery T M; Nishimura S; Yamaizumi Z; Weinstein I B
Identification of an intracellular protein that specifically interacts with photoaffinity-labeled oncogenic p21 protein.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(22):8678-82.
1988: Ronai Z A; Weinstein I B
Identification of a UV-induced trans-acting protein that stimulates polyomavirus DNA replication.
Journal of virology 1988;62(3):1057-60.
1988: Ronai Z A; Okin E; Weinstein I B
Ultraviolet light induces the expression of oncogenes in rat fibroblast and human keratinocyte cells.
Oncogene 1988;2(2):201-4.

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