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Renza Roncarati

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TOP 3
Karen L Marquis; Rachel L Navarra; Claudine Pulicicchio; Renza Roncarati; Carla Scali; Georg C Terstappen; Chiara Ghiron; Steven M Grauer; Simon Haydar; Flora Jow; Cody Kelley; Julie A Brennan; thomas Comery; John Dunlop
Preclinical assessment of an adjunctive treatment approach for cognitive impairment associated with schizophrenia using the alpha7 nicotinic acetylcholine receptor agonist WYE-103914/SEN34625.
Lara Rossini; Yuichi Hashimoto; Hiroaki Suzuki; Megumi Kurita; Marco Gianfriddo; Carla Scali; Renza Roncarati; Davide Franceschini; Giuseppe Pollio; Lorenza Trabalzini; Georg C Terstappen; Masaaki Matsuoka; Andrea Caricasole
VSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin.
Chiara Ghiron; Simon N Haydar; Suzan Aschmies; Hendrick Bothmann; Cristiana Castaldo; Giuseppe Cocconcelli; Thomas A Comery; Li Di; John Dunlop; Tim Lock; Angela Kramer; Dianne Kowal; Flora Jow; Steve Grauer; Boyd Harrison; Salvatore La Rosa; laura maccari; Karen L Marquis; Iolanda Micco; Arianna Nencini; Joanna Quinn; Albert J Robichaud; Renza Roncarati; Carla Scali; Georg C Terstappen; Elisa Turlizzi; Michela Valacchi; Maurizio Varrone; Riccardo Zanaletti; Ugo Zanelli
Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914).

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All Publications

2011: Karen L Marquis; Rachel L Navarra; Claudine Pulicicchio; Renza Roncarati; Carla Scali; Georg C Terstappen; Chiara Ghiron; Steven M Grauer; Simon Haydar; Flora Jow; Cody Kelley; Julie A Brennan; thomas Comery; John Dunlop
Preclinical assessment of an adjunctive treatment approach for cognitive impairment associated with schizophrenia using the alpha7 nicotinic acetylcholine receptor agonist WYE-103914/SEN34625.
Psychopharmacology 2011;218(4):635-47.
2011: Lara Rossini; Yuichi Hashimoto; Hiroaki Suzuki; Megumi Kurita; Marco Gianfriddo; Carla Scali; Renza Roncarati; Davide Franceschini; Giuseppe Pollio; Lorenza Trabalzini; Georg C Terstappen; Masaaki Matsuoka; Andrea Caricasole
VSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(6):1983-2000.
2010: Chiara Ghiron; Simon N Haydar; Suzan Aschmies; Hendrick Bothmann; Cristiana Castaldo; Giuseppe Cocconcelli; Thomas A Comery; Li Di; John Dunlop; Tim Lock; Angela Kramer; Dianne Kowal; Flora Jow; Steve Grauer; Boyd Harrison; Salvatore La Rosa; laura maccari; Karen L Marquis; Iolanda Micco; Arianna Nencini; Joanna Quinn; Albert J Robichaud; Renza Roncarati; Carla Scali; Georg C Terstappen; Elisa Turlizzi; Michela Valacchi; Maurizio Varrone; Riccardo Zanaletti; Ugo Zanelli
Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914).
Journal of medicinal chemistry 2010;53(11):4379-89.
2010: Georg C Terstappen; Renza Roncarati; John Dunlop; Ravikumar Peri
Screening technologies for ion channel drug discovery.
Future medicinal chemistry 2010;2(5):715-30.
2009: Simon N Haydar; Chiara Ghiron; Laura Bettinetti; Hendrick Bothmann; thomas Comery; John Dunlop; Salvatore La Rosa; Iolanda Micco; Martina Pollastrini; Joanna Quinn; Renza Roncarati; Carla Scali; Michela Valacchi; Maurizio Varrone; Riccardo Zanaletti
SAR and biological evaluation of SEN12333/WAY-317538: Novel alpha 7 nicotinic acetylcholine receptor agonist.
Bioorganic & medicinal chemistry 2009;17(14):5247-58.
2009: Renza Roncarati; Carla Scali; thomas Comery; Steven M Grauer; Suzan Aschmi; Hendrick Bothmann; Brian Jow; Dianne Kowal; Marco Gianfriddo; Cody Kelley; Ugo Zanelli; Chiara Ghiron; Simon Haydar; John Dunlop; Georg C Terstappen
Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders.
The Journal of pharmacology and experimental therapeutics 2009;329(2):459-68.
2009: John Dunlop; Tim Lock; Brian Jow; Fabrizio Sitzia; Steven M Grauer; Flora Jow; Angela Kramer; Mark Bowlby; Andrew Randall; Dianne Kowal; Adam Gilbert; thomas Comery; James Larocque; Veronica Soloveva; Jon Brown; Renza Roncarati
Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide).
The Journal of pharmacology and experimental therapeutics 2009;328(3):766-76.
2008: Tamara Seredenina; Teresa Ferraro; Georg C Terstappen; Andrea Caricasole; Renza Roncarati
Molecular cloning and characterization of a novel human variant of RIC-3, a putative chaperone of nicotinic acetylcholine receptors.
Bioscience reports 2008;28(6):299-306.
2008: Giuseppe Pollio; Jeroen J M Hoozemans; Claus A Andersen; Renza Roncarati; Maria Cristina Rosi; Elise S van Haastert; Tamara Seredenina; Daniela Diamanti; Stefano Gotta; Anna Fiorentini; Letizia Magnoni; Roberto Raggiaschi; Annemieke J M Rozemuller; Fiorella Casamenti; Andrea Caricasole; Georg C Terstappen
Increased expression of the oligopeptidase THOP1 is a neuroprotective response to Abeta toxicity.
Neurobiology of disease 2008;31(1):145-58.
2008: Renza Roncarati; Tamara Seredenina; Brian Jow; Flora Jow; Silvia Papini; Angela Kramer; Hendrick Bothmann; John Dunlop; Georg C Terstappen
Functional properties of alpha7 nicotinic acetylcholine receptors co-expressed with RIC-3 in a stable recombinant CHO-K1 cell line.
Assay and drug development technologies 2008;6(2):181-93.
2007: John Dunlop; Renza Roncarati; Brian Jow; Hendrick Bothmann; Tim Lock; Dianne Kowal; Mark Bowlby; Georg C Terstappen
In vitro screening strategies for nicotinic receptor ligands.
Biochemical pharmacology 2007;74(8):1172-81.
2006: Ilaria Decimo; Renza Roncarati; Silvia Grasso; Marcel Clemens; Christian Chiamulera; Guido Fumagalli
SK3 trafficking in hippocampal cells: the role of different molecular domains.
Bioscience reports 2006;26(6):399-412.
2006: Carla Scali; Filippo Caraci; Marco Gianfriddo; Enrica Diodato; Renza Roncarati; Giuseppe Pollio; Giovanni Gaviraghi; Agata Copani; Ferdinando Nicoletti; Georg C Terstappen; Andrea Caricasole
Inhibition of Wnt signaling, modulation of Tau phosphorylation and induction of neuronal cell death by DKK1.
Neurobiology of disease 2006;24(2):254-65.
2005: Renza Roncarati; Ilaria Decimo; Guido Fumagalli
Assembly and trafficking of human small conductance Ca2+-activated K+ channel SK3 are governed by different molecular domains.
Molecular and cellular neurosciences 2005;28(2):314-25.
2002: Corrado Carignani; Renza Roncarati; Rebecca Rimini; Georg C Terstappen
Pharmacological and molecular characterisation of SK3 channels in the TE671 human medulloblastoma cell line.
Brain research 2002;939(1-2):11-8.
2002: Andrea Caricasole; Ezio Bettini; Cinzia F Sala; Renza Roncarati; Naoki Kobayashi; Fabrizio Caldara; Kaoru Goto; Georg C Terstappen
Molecular cloning and characterization of the human diacylglycerol kinase beta (DGKbeta) gene: alternative splicing generates DGKbeta isotypes with different properties.
The Journal of biological chemistry 2002;277(7):4790-6.
2001: Georg C Terstappen; Giordano Pula; Corrado Carignani; M X Chen; Renza Roncarati
Pharmacological characterisation of the human small conductance calcium-activated potassium channel hSK3 reveals sensitivity to tricyclic antidepressants and antipsychotic phenothiazines.
Neuropharmacology 2001;40(6):772-83.
2001: Renza Roncarati; Marzia Di Chio; A Sava; Georg C Terstappen; Guido Fumagalli
Presynaptic localization of the small conductance calcium-activated potassium channel SK3 at the neuromuscular junction.
Neuroscience 2001;104(1):253-62.
2000: Andrea Caricasole; Cinzia F Sala; Renza Roncarati; E Formenti; Georg C Terstappen
Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1).
Biochimica et biophysica acta 2000;1517(1):63-72.