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Lars Rönnblom

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Co-Publications
Name
45
Alm, Gunnar
18
Eloranta, Maija-Leena
11
Nordmark, Gunnel
10
Sturfelt, Gunnar
8
Syvänen, Ann-Christine
7
Vallin, HS
7
Truedsson, Lennart
6
Sigurdsson, Snaevar
5
Perers, Anders
5
Gunnarsson, Iva
5
Blomberg, Stina
5
Jönsen, Andreas
5
Båve, Ullvi
5
Cederblad, B
4
Bengtsson, Anders

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Publications

TOP 3
Lood Christian; Gullstrand Birgitta; Truedsson Lennart; Olin Anders I; Alm Gunnar V; Rönnblom Lars; Sturfelt Gunnar; Eloranta Maija-Leena; Bengtsson Anders A
C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis.
Isaksson Magnus; Ardesjö Brita; Rönnblom Lars; Kämpe Olle; Lassmann Hans; Eloranta Maija-Leena; Lobell Anna
Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE.
Rönnblom Lars; Alm Gunnar V; Eloranta Maija-Leena
Type I interferon and lupus.

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All Publications

2009: Lood Christian; Gullstrand Birgitta; Truedsson Lennart; Olin Anders I; Alm Gunnar V; Rönnblom Lars; Sturfelt Gunnar; Eloranta Maija-Leena; Bengtsson Anders A
C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis.
Arthritis and rheumatism 2009;60(10):3081-90.
2009: Isaksson Magnus; Ardesjö Brita; Rönnblom Lars; Kämpe Olle; Lassmann Hans; Eloranta Maija-Leena; Lobell Anna
Plasmacytoid DC promote priming of autoimmune Th17 cells and EAE.
European journal of immunology 2009;39(10):2925-35.
2009: Rönnblom Lars; Alm Gunnar V; Eloranta Maija-Leena
Type I interferon and lupus.
Current opinion in rheumatology 2009;21(5):471-7.
2009: Eloranta Maija-Leena; Lövgren Tanja; Finke Doreen; Mathsson Linda; Rönnelid Johan; Kastner Berthold; Alm Gunnar V; Rönnblom Lars
Regulation of the interferon-alpha production induced by RNA-containing immune complexes in plasmacytoid dendritic cells.
Arthritis and rheumatism 2009;60(8):2418-27.
2009: Finke Doreen; Eloranta Maija-Leena; Rönnblom Lars
Endogenous type I interferon inducers in autoimmune diseases.
Autoimmunity 2009;42(4):349-52.
2009: Nordmark G; Kristjansdottir G; Theander E; Eriksson P; Brun J G; Wang C; Padyukov L; Truedsson L; Alm G; Eloranta M-L; Jonsson R; Rönnblom L; Syvänen A-C
Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome.
Genes and immunity 2009;10(1):68-76.
2008: Sigurdsson Snaevar; Nordmark Gunnel; Garnier Sophie; Grundberg Elin; Kwan Tony; Nilsson Olof; Eloranta Maija-Leena; Gunnarsson Iva; Svenungsson Elisabet; Sturfelt Gunnar; Bengtsson Anders A; Jönsen Andreas; Truedsson Lennart; Rantapää-Dahlqvist Solbritt; Eriksson Catharina; Alm Gunnar; Göring Harald H H; Pastinen Tomi; Syvänen Ann-Christine; Rönnblom Lars
A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.
Human molecular genetics 2008;17(18):2868-76.
2008: Sigurdsson Snaevar; Göring Harald H H; Kristjansdottir Gudlaug; Milani Lili; Nordmark Gunnel; Sandling Johanna K; Eloranta Maija-Leena; Feng Di; Sangster-Guity Niquiche; Gunnarsson Iva; Svenungsson Elisabet; Sturfelt Gunnar; Jönsen Andreas; Truedsson Lennart; Barnes Betsy J; Alm Gunnar; Rönnblom Lars; Syvänen Ann-Christine
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus.
Human molecular genetics 2008;17(6):872-81.
2008: Hom Geoffrey; Graham Robert R; Modrek Barmak; Taylor Kimberly E; Ortmann Ward; Garnier Sophie; Lee Annette T; Chung Sharon A; Ferreira Ricardo C; Pant P V Krishna; Ballinger Dennis G; Kosoy Roman; Demirci F Yesim; Kamboh M Ilyas; Kao Amy H; Tian Chao; Gunnarsson Iva; Bengtsson Anders A; Rantapää-Dahlqvist Solbritt; Petri Michelle; Manzi Susan; Seldin Michael F; Rönnblom Lars; Syvänen Ann-Christine; Criswell Lindsey A; Gregersen Peter K; Behrens Timothy W
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.
The New England journal of medicine 2008;358(9):900-9.
2008: Rönnblom L; Pascual V
The innate immune system in SLE: type I interferons and dendritic cells.
Lupus 2008;17(5):394-9.
2007: Linga-Reddy M V Prasad; Gunnarsson I; Svenungsson E; Sturfelt G; Jönsen A; Truedsson L; Nordmark G; Rönnblom L; Alarcón-Riquelme M E
A polymorphic variant in the MHC2TA gene is not associated with systemic lupus erythematosus.
Tissue antigens 2007;70(5):412-4.
2007: Eloranta Maija-Leena; Barbasso Helmers Sevim; Ulfgren Ann-Kristin; Rönnblom Lars; Alm Gunnar V; Lundberg Ingrid E
A possible mechanism for endogenous activation of the type I interferon system in myositis patients with anti-Jo-1 or anti-Ro 52/anti-Ro 60 autoantibodies.
Arthritis and rheumatism 2007;56(9):3112-24.
2007: Sigurdsson Snaevar; Padyukov Leonid; Kurreeman Fina A S; Liljedahl Ulrika; Wiman Ann-Christin; Alfredsson Lars; Toes René; Rönnelid Johan; Klareskog Lars; Huizinga Tom W J; Alm Gunnar; Syvänen Ann-Christine; Rönnblom Lars
Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis.
Arthritis and rheumatism 2007;56(7):2202-10.
2007: Graham Robert R; Kyogoku Chieko; Sigurdsson Snaevar; Vlasova Irina A; Davies Leela R L; Baechler Emily C; Plenge Robert M; Koeuth Thearith; Ortmann Ward A; Hom Geoffrey; Bauer Jason W; Gillett Clarence; Burtt Noel; Cunninghame Graham Deborah S; Onofrio Robert; Petri Michelle; Gunnarsson Iva; Svenungsson Elisabet; Rönnblom Lars; Nordmark Gunnel; Gregersen Peter K; Moser Kathy; Gaffney Patrick M; Criswell Lindsey A; Vyse Timothy J; Syvänen Ann-Christine; Bohjanen Paul R; Daly Mark J; Behrens Timothy W; Altshuler David
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(16):6758-63.
2006: Lövgren Tanja; Eloranta Maija-Leena; Kastner Berthold; Wahren-Herlenius Marie; Alm Gunnar V; Rönnblom Lars
Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA.
Arthritis and rheumatism 2006;54(6):1917-27.
2006: Nordmark Gunnel; Alm Gunnar V; Rönnblom Lars
Mechanisms of Disease: primary Sjögren's syndrome and the type I interferon system.
Nature clinical practice. Rheumatology 2006;2(5):262-9.
2006: Rönnblom Lars; Eloranta Maija-Leena; Alm Gunnar V
The type I interferon system in systemic lupus erythematosus.
Arthritis and rheumatism 2006;54(2):408-20.
2005: Nordmark Gunnel; Bengtsson Christine; Larsson Anders; Karlsson F Anders; Sturfelt Gunnar; Rönnblom Lars
Effects of dehydroepiandrosterone supplement on health-related quality of life in glucocorticoid treated female patients with systemic lupus erythematosus.
Autoimmunity 2005;38(7):531-40.
2005: Vahlquist Anders; Westermark Per; Ståhle Elisabeth; Venge Per; Påhlman Lars; Hällgren Roger; Rönnblom Lars; Kämpe Olle; Wiklund Lars; Aquilonius Sten-Magnus; Alm Albert
[Burdensome rules for clinical trials are not in proportion to benefits for the patient]
Läkartidningen 2005;102(23):1832, 1834; discussion 1834.
2005: Båve Ullvi; Nordmark Gunnel; Lövgren Tanja; Rönnelid Johan; Cajander Stefan; Eloranta Maija-Leena; Alm Gunnar V; Rönnblom Lars
Activation of the type I interferon system in primary Sjögren's syndrome: a possible etiopathogenic mechanism.
Arthritis and rheumatism 2005;52(4):1185-95.
2005: Sigurdsson Snaevar; Nordmark Gunnel; Göring Harald H H; Lindroos Katarina; Wiman Ann-Christin; Sturfelt Gunnar; Jönsen Andreas; Rantapää-Dahlqvist Solbritt; Möller Bozena; Kere Juha; Koskenmies Sari; Widén Elisabeth; Eloranta Maija-Leena; Julkunen Heikki; Kristjansdottir Helga; Steinsson Kristjan; Alm Gunnar; Rönnblom Lars; Syvänen Ann-Christine
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
American journal of human genetics 2005;76(3):528-37.
2004: Lövgren Tanja; Eloranta Maija-Leena; Båve Ullvi; Alm Gunnar V; Rönnblom Lars
Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.
Arthritis and rheumatism 2004;50(6):1861-72.
2004: Ekdahl Kristina N; Bengtsson Anders A; Andersson Jonas; Elgue Graciela; Rönnblom Lars; Sturfelt Gunnar; Nilsson Bo
Thrombotic disease in systemic lupus erythematosus is associated with a maintained systemic platelet activation.
British journal of haematology 2004;125(1):74-8.
2003: Rönnblom Lars; Eloranta Maija-Leena; Alm Gunnar V
Role of natural interferon-alpha producing cells (plasmacytoid dendritic cells) in autoimmunity.
Autoimmunity 2003;36(8):463-72.
2003: Blomberg Stina; Eloranta Maija-Leena; Magnusson Mattias; Alm Gunnar V; Rönnblom Lars
Expression of the markers BDCA-2 and BDCA-4 and production of interferon-alpha by plasmacytoid dendritic cells in systemic lupus erythematosus.
Arthritis and rheumatism 2003;48(9):2524-32.
2003: Båve Ullvi; Magnusson Mattias; Eloranta Maija-Leena; Perers Anders; Alm Gunnar V; Rönnblom Lars
Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):3296-302.
2003: Forsman Anna; Uzameckis Dmitrijs; Rönnblom Lars; Baecklund Eva; Aleskog Anna; Bindra Amarinder; Pipkorn Rüdiger; Lejniece Sandra; Kozireva Svetlana; Murovska Modra; Blomberg Jonas
Single-tube nested quantitative PCR: a rational and sensitive technique for detection of retroviral DNA. Application to RERV-H/HRV-5 and confirmation of its rabbit origin.
Journal of virological methods 2003;111(1):1-11.
2003: Nordmark G; Rorsman F; Rönnblom L; Cajander S; Taussig M J; Kämpe O; Winqvist O
Autoantibodies to alpha-fodrin in primary Sjögren's syndrome and SLE detected by an in vitro transcription and translation assay.
Clinical and experimental rheumatology 2003;21(1):49-56.
2003: Jönsen A; Bengtsson A A; Nived O; Ryberg B; Truedsson L; Rönnblom L; Alm G V; Sturfelt G
The heterogeneity of neuropsychiatric systemic lupus erythematosus is reflected in lack of association with cerebrospinal fluid cytokine profiles.
Lupus 2003;12(11):846-50.
2003: Rönnblom Lars; Alm Gunnar V
Systemic lupus erythematosus and the type I interferon system.
Arthritis research & therapy 2003;5(2):68-75.
2002: Rönnblom Lars; Alm Gunnar V
The natural interferon-alpha producing cells in systemic lupus erythematosus.
Human immunology 2002;63(12):1181-93.
2002: Lindroos Katarina; Sigurdsson Snaevar; Johansson Karin; Rönnblom Lars; Syvänen Ann-Christine
Multiplex SNP genotyping in pooled DNA samples by a four-colour microarray system.
Nucleic acids research 2002;30(14):e70.
2002: Sköldberg Filip; Rönnblom Lars; Thornemo Maria; Lindahl Anders; Bird Phillip I; Rorsman Fredrik; Kämpe Olle; Landgren Eva
Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus.
Biochemical and biophysical research communications 2002;291(4):951-8.
2001: Magnusson M; Magnusson S; Vallin H; Rönnblom L; Alm G V
Importance of CpG dinucleotides in activation of natural IFN-alpha-producing cells by a lupus-related oligodeoxynucleotide.
Scandinavian journal of immunology 2001;54(6):543-50.
2001: Rönnblom L; Alm G V
A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus.
The Journal of experimental medicine 2001;194(12):F59-63.
2001: Båve U; Vallin H; Alm G V; Rönnblom L
Activation of natural interferon-alpha producing cells by apoptotic U937 cells combined with lupus IgG and its regulation by cytokines.
Journal of autoimmunity 2001;17(1):71-80.
2001: Rönnblom L; Alm G V
An etiopathogenic role for the type I IFN system in SLE.
Trends in immunology 2001;22(8):427-31.
2001: Blomberg S; Eloranta M L; Cederblad B; Nordlin K; Alm G V; Rönnblom L
Presence of cutaneous interferon-alpha producing cells in patients with systemic lupus erythematosus.
Lupus 2001;10(7):484-90.
2000: Båve U; Alm G V; Rönnblom L
The combination of apoptotic U937 cells and lupus IgG is a potent IFN-alpha inducer.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3519-26.
2000: Bengtsson A A; Sturfelt G; Truedsson L; Blomberg J; Alm G; Vallin H; Rönnblom L
Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies.
Lupus 2000;9(9):664-71.
2000: Pourmand N; Blomberg S; Rönnblom L; Karlsson-Parra A; Pettersson I; Wahren-Herlenius M
Ro 52kD autoantibodies are detected in a subset of ANA-negative sera.
Scandinavian journal of rheumatology 2000;29(2):116-23.
1999: Vallin H; Perers A; Alm G V; Rönnblom L
Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-alpha inducer in systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(11):6306-13.
1999: Vallin H; Blomberg S; Alm G V; Cederblad B; Rönnblom L
Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon-alpha (IFN-alpha) production acting on leucocytes resembling immature dendritic cells.
Clinical and experimental immunology 1999;115(1):196-202.
1998: Cederblad B; Blomberg S; Vallin H; Perers A; Alm G V; Rönnblom L
Patients with systemic lupus erythematosus have reduced numbers of circulating natural interferon-alpha- producing cells.
Journal of autoimmunity 1998;11(5):465-70.
1997: Ekdahl K N; Rönnblom L; Sturfelt G; Nilsson B
Increased phosphate content in complement component C3, fibrinogen, vitronectin, and other plasma proteins in systemic lupus erythematosus: covariation with platelet activation and possible association with thrombosis.
Arthritis and rheumatism 1997;40(12):2178-86.
1997: Nordmark G; Boquist L; Rönnblom L
Limited Wegener's granulomatosis with central nervous system involvement and fatal outcome.
Journal of internal medicine 1997;242(5):433-6.
1997: Rönnblom L E; Perers A; Vallin H S; Eriksson I; Osterlind A; Cederblad B; Alm G
Detection of serum interferon-alpha by dissociation-enhanced lanthanide fluoroimmunoassay. Studies of patients with acute viral and bacterial infections.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1997;105(7):531-6.
1992: Rönnblom L E; Janson E T; Perers A; Oberg K E; Alm G V
Characterization of anti-interferon-alpha antibodies appearing during recombinant interferon-alpha 2a treatment.
Clinical and experimental immunology 1992;89(3):330-5.
1992: Janson E T; Rönnblom L; Ahlström H; Grandér D; Alm G; Einhorn S; Oberg K
Treatment with alpha-interferon versus alpha-interferon in combination with streptozocin and doxorubicin in patients with malignant carcinoid tumors: a randomized trial.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1992;3(8):635-8.
1991: Rönnblom L E; Alm G V; Oberg K E
Autoimmunity after alpha-interferon therapy for malignant carcinoid tumors.
Annals of internal medicine 1991;115(3):178-83.
1991: Rönnblom L E; Forsberg H; Evrin P E
Increased level of HLA-DR-expressing T lymphocytes in peripheral blood from patients with idiopathic dilated cardiomyopathy.
Cardiology 1991;78(3):161-7.
1991: Rönnblom L E; Alm G V; Oberg K
Autoimmune phenomena in patients with malignant carcinoid tumors during interferon-alpha treatment.
Acta oncologica (Stockholm, Sweden) 1991;30(4):537-40.
1990: Rönnblom L E; Alm G V; Oberg K E
Possible induction of systemic lupus erythematosus by interferon-alpha treatment in a patient with a malignant carcinoid tumour.
Journal of internal medicine 1990;227(3):207-10.
1988: Rönnblom L; Cederblad B; Sandberg K; Alm G V
Determination of herpes simplex virus-induced alpha interferon-secreting human blood leucocytes by a filter immuno-plaque assay.
Scandinavian journal of immunology 1988;27(2):165-70.
1988: Rönnblom L; Sjöberg O; Evrin P E; Nethander G
Phenotypes of peripheral blood leukocytes in Melkersson-Rosenthal syndrome.
Acta dermato-venereologica 1988;68(2):154-8.
1986: Rönnblom L; Forsum U; Evrin P E; Gillnäs T; Nethander G
Intralesional T lymphocyte phenotypes and HLA-DR expression in Melkersson-Rosenthal syndrome.
International journal of oral and maxillofacial surgery 1986;15(5):614-9.
1985: Funa K; Ramstedt U; Rönnblom L; Alm G V
Human peripheral blood null lymphocytes stimulated by Staphylococcus aureus Cowan I produce atypical acid-labile interferon in vitro.
Scandinavian journal of immunology 1985;21(1):55-62.
1984: Claesson K; Rönnblom L; Alm G; Tufveson G
Antiviral activity appearing in serum of renal transplant recipients. Its possible relation to immunological rejection.
Transplantation 1984;38(1):32-4.
1983: Funa K; Alm G V; Rönnblom L; Oberg K
Evaluation of the natural killer cell-interferon system in patients with mid-gut carcinoid tumours treated with leucocyte interferon.
Clinical and experimental immunology 1983;53(3):716-24.
1983: Rönnblom L; Ramstedt U; Alm G V
Properties of human natural interferon-producing cells stimulated by tumor cell lines.
European journal of immunology 1983;13(6):471-6.
1983: Rönnblom L; Forsgren A; Alm G V
Characterization of interferons induced by bacteria and interferon-producing leukocytes in human peripheral blood.
Infection and immunity 1983;40(1):126-32.
1983: Rönnblom L; Ojo-Amaize E A; Franzén L; Wigzell H; Alm G V
Plasmodium falciparum parasites induce interferon production in human peripheral blood 'null' cells in vitro.
Parasite immunology 1983;5(2):165-72.
1982: Rönnblom L; Funa K; Ersson B; Alm G V
Lectins as inducers of interferon-gamma production in human lymphocytes: lentil lectin is highly efficient.
Scandinavian journal of immunology 1982;16(4):327-31.
1982: Rönnblom L; Alm G V
Limiting dilution analysis of human peripheral blood mononuclear leukocytes that react to human amnion cells and protect these against viral challenge.
European journal of immunology 1982;12(5):437-41.

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