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Robert Bigsby

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Joseph R Dynlacht; Joy Garrett; Jessica Nees; Shailaja Valluri; Andrea Caperell-Grant; Colleen DesRosiers; Robert M Bigsby
Age and hormonal status as determinants of cataractogenesis induced by ionizing radiation. II. Sparsely ionizing (low-LET) radiation.
Robert M Bigsby; Andrea Caperell-Grant
The role for estrogen receptor-alpha and prolactin receptor in sex-dependent DEN-induced liver tumorigenesis.
Joseph R Dynlacht; Shailaja Valluri; Joy Garrett; Marc S Mendonca; Jennifer T Lopez; Andrea Caperell-Grant; Robert M Bigsby
Age and hormonal status as determinants of cataractogenesis induced by ionizing radiation. I. Densely ionizing (high-LET) radiation.

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All Publications

2012: Joseph R Dynlacht; Joy Garrett; Jessica Nees; Shailaja Valluri; Andrea Caperell-Grant; Colleen DesRosiers; Robert M Bigsby
Age and hormonal status as determinants of cataractogenesis induced by ionizing radiation. II. Sparsely ionizing (low-LET) radiation.
Radiation research 2012;178(4):260-5.
2011: Robert M Bigsby; Andrea Caperell-Grant
The role for estrogen receptor-alpha and prolactin receptor in sex-dependent DEN-induced liver tumorigenesis.
Carcinogenesis 2011;32(8):1162-6.
2011: Joseph R Dynlacht; Shailaja Valluri; Joy Garrett; Marc S Mendonca; Jennifer T Lopez; Andrea Caperell-Grant; Robert M Bigsby
Age and hormonal status as determinants of cataractogenesis induced by ionizing radiation. I. Densely ionizing (high-LET) radiation.
Radiation research 2011;175(1):37-43.
2010: Mark A Henderson; Shailaja Valluri; Joy Garrett; Jennifer T Lopez; Andrea Caperell-Grant; Marc S Mendonca; Adam Rusek; Robert M Bigsby; Joseph R Dynlacht
Effects of estrogen and gender on cataractogenesis induced by high-LET radiation.
Radiation research 2010;173(2):191-6.
2009: Minghai Shao; Liyun Cao; Changyu Shen; Minati Satpathy; Bhadrani Chelladurai; Robert M Bigsby; Harikrishna Nakshatri; Daniela Matei
Epithelial-to-mesenchymal transition and ovarian tumor progression induced by tissue transglutaminase.
Cancer research 2009;69(24):9192-201.
2009: Mark A Henderson; Shailaja Valluri; Colleen DesRosiers; Jennifer T Lopez; Christopher N Batuello; Andrea Caperell-Grant; Marc S Mendonca; Eva-Marie Powers; Robert M Bigsby; Joseph R Dynlacht
Effect of gender on radiation-induced cataractogenesis.
Radiation research 2009;172(1):129-33.
2009: Robert M Bigsby; Shailaja Valluri; Jennifer Lopez; Marc S Mendonca; Andrea Caperell-Grant; Colleen DesRosiers; Joseph R Dynlacht
Ovarian hormone modulation of radiation-induced cataractogenesis: dose-response studies.
Investigative ophthalmology & visual science 2009;50(7):3304-10.
2009: Xinghua Qiu; Robert M Bigsby; Ronald A Hites
Hydroxylated metabolites of polybrominated diphenyl ethers in human blood samples from the United States.
Environmental health perspectives 2009;117(1):93-8.
2008: Joseph R Dynlacht; Shailaja Valluri; Jennifer Lopez; Falon Greer; Colleen DesRosiers; Andrea Caperell-Grant; Marc S Mendonca; Robert M Bigsby
Estrogen protects against radiation-induced cataractogenesis.
Radiation research 2008;170(6):758-64.
2008: Mercado Feliciano Minerva; Robert M Bigsby
Hydroxylated metabolites of the polybrominated diphenyl ether mixture DE-71 are weak estrogen receptor-alpha ligands.
Environmental health perspectives 2008;116(10):1315-21.
2008: Xinghua Long; Meiyun Fan; Robert M Bigsby; Kenneth P Nephew
Apigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor-alpha-dependent and estrogen receptor-alpha-independent mechanisms.
Molecular cancer therapeutics 2008;7(7):2096-108.
2008: Dongmei Wang; Zhenwen Zhao; Andrea Caperell-Grant; Gong Yang; Samuel C Mok; Jinsong Liu; Robert M Bigsby; Yan Xu
S1P differentially regulates migration of human ovarian cancer and human ovarian surface epithelial cells.
Molecular cancer therapeutics 2008;7(7):1993-2002.
2008: Zane Hammoud; Bailin Tan; Sunil Badve; Robert M Bigsby
Estrogen promotes tumor progression in a genetically defined mouse model of lung adenocarcinoma.
Endocrine-related cancer 2008;15(2):475-83.
2008: Mercado Feliciano Minerva; Robert M Bigsby
The polybrominated diphenyl ether mixture DE-71 is mildly estrogenic.
Environmental health perspectives 2008;116(5):605-11.
2008: Bailin Tan; Xinghua Long; Harikrishna Nakshatri; Kenneth P Nephew; Robert M Bigsby
Striatin-3 gamma inhibits estrogen receptor activity by recruiting a protein phosphatase.
Journal of molecular endocrinology 2008;40(5):199-210.
2007: Minati Satpathy; Liyun Cao; Roxana Pincheira; Robert Emerson; Robert M Bigsby; Harikrishna Nakshatri; Daniela Matei
Enhanced peritoneal ovarian tumor dissemination by tissue transglutaminase.
Cancer research 2007;67(15):7194-202.
2007: Xinghua Qiu; Mercado Feliciano Minerva; Robert M Bigsby; Ronald A Hites
Measurement of polybrominated diphenyl ethers and metabolites in mouse plasma after exposure to a commercial pentabromodiphenyl ether mixture.
Environmental health perspectives 2007;115(7):1052-8.
2007: Susan Brutkiewicz; Marc S Mendonca; Keith Stantz; Kathleen Comerford; Robert M Bigsby; Gary Hutchins; Mark G Goebl; Maureen Harrington
The expression level of luciferase within tumour cells can alter tumour growth upon in vivo bioluminescence imaging.
Luminescence : the journal of biological and chemical luminescence 2007;22(3):221-8.
2006: Cheri L Stowell; Kevin K Barvian; Peter C M Young; Robert M Bigsby; Dawn E Verdugo; Carolyn R Bertozzi; Theodore S Widlanski
A role for sulfation-desulfation in the uptake of bisphenol a into breast tumor cells.
Chemistry & biology 2006;13(8):891-7.
2006: Joseph R Dynlacht; Craig Tyree; Shailaja Valluri; Colleen DesRosiers; Andrea Caperell-Grant; Marc S Mendonca; Robert D Timmerman; Robert M Bigsby
Effect of estrogen on radiation-induced cataractogenesis.
Radiation research 2006;165(1):9-15.
2004: Robert M Bigsby; Andrea Caperell-Grant; Nicholas Berry; Kenneth P Nephew; Dennis Lubahn
Estrogen induces a systemic growth factor through an estrogen receptor-alpha-dependent mechanism.
Biology of reproduction 2004;70(1):178-83.
2003: Suresh Kumar; Hiromitsu Kishimoto; Hui Lin Chua; Sunil Badve; Kathy D Miller; Robert M Bigsby; Harikrishna Nakshatri
Interleukin-1 alpha promotes tumor growth and cachexia in MCF-7 xenograft model of breast cancer.
The American journal of pathology 2003;163(6):2531-41.
2003: Colleen DesRosiers; Marc S Mendonca; Craig Tyree; Vadim Moskvin; Morris Bank; Leo Massaro; Robert M Bigsby; Andrea Caperall-Grant; Shailaja Valluri; Joseph R Dynlacht; Robert D Timmerman
Use of the Leksell Gamma Knife for localized small field lens irradiation in rodents.
Technology in cancer research & treatment 2003;2(5):449-54.
2003: Anita Mazdai; Nathan G Dodder; Mary Pell Abernathy; Ronald A Hites; Robert M Bigsby
Polybrominated diphenyl ethers in maternal and fetal blood samples.
Environmental health perspectives 2003;111(9):1249-52.
2003: Meiyun Fan; Robert M Bigsby; Kenneth P Nephew
The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast cancer cells.
Molecular endocrinology (Baltimore, Md.) 2003;17(3):356-65.
2002: Robert M Bigsby
Synergistic tumor promoter effects of estrone and progesterone in methylnitrosourea-induced rat mammary cancer.
Cancer letters 2002;179(2):113-9.
2002: Robert M Bigsby
Control of growth and differentiation of the endometrium: the role of tissue interactions.
Annals of the New York Academy of Sciences 2002;955():110-7; discussion 118, 396-406.
2002: Meiyun Fan; Xinghua Long; Jason A Bailey; Chad A Reed; Elizabeth Osborne; Edward A Gize; Eric A Kirk; Robert M Bigsby; Kenneth P Nephew
The activating enzyme of NEDD8 inhibits steroid receptor function.
Molecular endocrinology (Baltimore, Md.) 2002;16(2):315-30.
2001: X Long; E A Gize; Kenneth P Nephew; Robert M Bigsby
Evidence for estrogenic contamination of the MAPK inhibitor PD98059.
Endocrinology 2001;142(12):5390-3.
2001: Jean A Hurteau; Bernadette M Allison; S A Brutkiewicz; Mark G Goebl; D K Heilman; Robert M Bigsby; Maureen A Harrington
Expression and subcellular localization of the cyclin-dependent kinase inhibitor p27(Kip1) in epithelial ovarian cancer.
Gynecologic oncology 2001;83(2):292-8.
2001: A Ahluwalia; Jean A Hurteau; Robert M Bigsby; Kenneth P Nephew
DNA methylation in ovarian cancer. II. Expression of DNA methyltransferases in ovarian cancer cell lines and normal ovarian epithelial cells.
Gynecologic oncology 2001;82(2):299-304.
2001: A Ahluwalia; P Yan; Jean A Hurteau; Robert M Bigsby; S H Jung; Hui-Ming (Tim) Huang; Kenneth P Nephew
DNA methylation and ovarian cancer. I. Analysis of CpG island hypermethylation in human ovarian cancer using differential methylation hybridization.
Gynecologic oncology 2001;82(2):261-8.
2001: Horacio Cárdenas; KA Burke; Robert M Bigsby; William F Pope; Kenneth P Nephew
Estrogen receptor beta in the sheep ovary during the estrous cycle and early pregnancy.
Biology of reproduction 2001;65(1):128-34.
2001: X Long; KA Burke; Robert M Bigsby; Kenneth P Nephew
Effects of the xenoestrogen bisphenol A on expression of vascular endothelial growth factor (VEGF) in the rat.
Experimental biology and medicine (Maywood, N.J.) 2001;226(5):477-83.
2001: E M Ulrich; K L Willett; Andrea Caperell-Grant; Robert M Bigsby; Ronald A Hites
Understanding enantioselective processes: a laboratory rat model for alpha-hexachlorocyclohexane accumulation.
Environmental science & technology 2001;35(8):1604-9.
2000: William W Hurd; Victor P Fomin; Viswanathan Natarajan; Haywood L Brown; Robert M Bigsby; Dawn M Singh
Expression of protein kinase C isozymes in nonpregnant and pregnant human myometrium.
American journal of obstetrics and gynecology 2000;183(6):1525-31.
2000: E M Ulrich; Andrea Caperell-Grant; S H Jung; Ronald A Hites; Robert M Bigsby
Environmentally relevant xenoestrogen tissue concentrations correlated to biological responses in mice.
Environmental health perspectives 2000;108(10):973-7.
2000: Kenneth P Nephew; S Ray; M Hlaing; A Ahluwalia; S D Wu; X Long; S M Hyder; Robert M Bigsby
Expression of estrogen receptor coactivators in the rat uterus.
Biology of reproduction 2000;63(2):361-7.
2000: KA Burke; D M Schroeder; R A Abel; S C Richardson; Robert M Bigsby; Kenneth P Nephew
Immunohistochemical detection of estrogen receptor alpha in male rat spinal cord during development.
Journal of neuroscience research 2000;61(3):329-37.
2000: X Long; Rosemary Steinmetz; Nira Ben-Jonathan; Andrea Caperell-Grant; P C Young; Kenneth P Nephew; Robert M Bigsby
Strain differences in vaginal responses to the xenoestrogen bisphenol A.
Environmental health perspectives 2000;108(3):243-7.
2000: Kenneth P Nephew; C M Choi; T C Polek; R McBride; Robert M Bigsby; S A Khan; Nader Husseinzadeh
Expression of fos and jun proto-oncogenes in benign versus malignant human uterine tissue.
Gynecologic oncology 2000;76(3):388-96.
2000: Kenneth P Nephew; X Long; Elizabeth Osborne; KA Burke; A Ahluwalia; Robert M Bigsby
Effect of estradiol on estrogen receptor expression in rat uterine cell types.
Biology of reproduction 2000;62(1):168-77.
1999: Robert M Bigsby; H Cardenas; Andrea Caperell-Grant; C J Grubbs
Protective effects of estrogen in a rat model of age-related cataracts.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):9328-32.
1999: Jean A Hurteau; Bernadette M Allison; GP Sutton; David H Moore; Katherine Y Look; William W Hurd; Robert M Bigsby
Transforming growth factor-beta differentially inhibits epithelial ovarian carcinoma cells from primary and metastatic isolates without up-regulation of p21WAF1.
Cancer 1999;85(8):1810-5.
1998: Rosemary Steinmetz; NA Mitchner; A Grant; DL Allen; Robert M Bigsby; Nira Ben-Jonathan
The xenoestrogen bisphenol A induces growth, differentiation, and c-fos gene expression in the female reproductive tract.
Endocrinology 1998;139(6):2741-7.
1998: AF Smith; Robert M Bigsby; R A Word; B Paul Herring
A 310-bp minimal promoter mediates smooth muscle cell-specific expression of telokin.
The American journal of physiology 1998;274(5 Pt 1):C1188-95; discussion C1187.
1998: Robert M Bigsby; Rosemary Steinmetz
Organochlorine residues and breast cancer.
The New England journal of medicine 1998;338(14):990; author reply 991.
1998: Jane Case-Smith; Robert M Bigsby; J Clutter
Perceptual-motor coupling in the development of grasp.
The American journal of occupational therapy : official publication of the American Occupational Therapy Association 1998;52(2):102-10.
1997: L M Everett; A Li; G Devaraju; Andrea Caperell-Grant; Robert M Bigsby
A novel estrogen-enhanced transcript identified in the rat uterus by differential display.
Endocrinology 1997;138(9):3836-41.
1997: Rosemary Steinmetz; N G Brown; DL Allen; Robert M Bigsby; Nira Ben-Jonathan
The environmental estrogen bisphenol A stimulates prolactin release in vitro and in vivo.
Endocrinology 1997;138(5):1780-6.
1997: M Tian; Hal E Broxmeyer; Y Fan; Z Lai; Shaobo Zhang; SM Aronica; Scott Cooper; Robert M Bigsby; Rosemary Steinmetz; S J Engle; A Mestek; Jonathan D Pollock; Michael N Lehman; Heiko T Jansen; M Ying; Peter J Stambrook; Jay A Tischfield; Lei Yu
Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice.
The Journal of experimental medicine 1997;185(8):1517-22.
1997: David H Moore; Bernadette M Allison; Katherine Y Look; GP Sutton; Robert M Bigsby
Collagenase expression in ovarian cancer cell lines.
Gynecologic oncology 1997;65(1):78-82.
1997: Robert M Bigsby; Andrea Caperell-Grant; B V Madhukar
Xenobiotics released from fat during fasting produce estrogenic effects in ovariectomized mice.
Cancer research 1997;57(5):865-9.
1997: L M Everett; Andrea Caperell-Grant; Robert M Bigsby
Mesenchymal-epithelial interactions in an in vitro model of neonatal mouse uterus.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997;214(1):49-53.
1996: Rosemary Steinmetz; P C Young; Andrea Caperell-Grant; E A Gize; B V Madhukar; Nira Ben-Jonathan; Robert M Bigsby
Novel estrogenic action of the pesticide residue beta-hexachlorocyclohexane in human breast cancer cells.
Cancer research 1996;56(23):5403-9.
1994: Rosemary Steinmetz; A Gutierrez-Hartmann; Robert M Bigsby; Nira Ben-Jonathan
Activation of the prolactin promoter in transfected GH3 cells by posterior pituitary cells.
Endocrinology 1994;135(6):2737-41.
1994: Robert M Bigsby; P C Young
Estrogenic effects of the antiprogestin onapristone (ZK98.299) in the rodent uterus.
American journal of obstetrics and gynecology 1994;171(1):188-94.
1994: Robert M Bigsby; A Li
Differentially regulated immediate early genes in the rat uterus.
Endocrinology 1994;134(4):1820-6.
1993: Robert M Bigsby; P C Young
Progesterone and dexamethasone inhibition of uterine epithelial cell proliferation: studies with antiprogesterone compounds in the neonatal mouse.
The Journal of steroid biochemistry and molecular biology 1993;46(2):253-7.
1993: Robert M Bigsby
Progesterone and dexamethasone inhibition of estrogen-induced synthesis of DNA and complement in rat uterine epithelium: effects of antiprogesterone compounds.
The Journal of steroid biochemistry and molecular biology 1993;45(4):295-301.
1992: Robert M Bigsby; A X Li; J Bomalaski; Frederick B Stehman; Katherine Y Look; GP Sutton
Immunohistochemical study of HER-2/neu, epidermal growth factor receptor, and steroid receptor expression in normal and malignant endometrium.
Obstetrics and gynecology 1992;79(1):95-100.
1991: Robert M Bigsby; Lynn Everett
Effects of progestin antagonists, glucocorticoids and estrogen on progesterone-induced protein secreted by rabbit endometrial stromal cells in culture.
The Journal of steroid biochemistry and molecular biology 1991;39(1):27-32.
1990: Robert M Bigsby; A X Li; K Luo; G R Cunha
Strain differences in the ontogeny of estrogen receptors in murine uterine epithelium.
Endocrinology 1990;126(5):2592-6.