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William Rose
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16
Fairchild, Craig
14
Long, Byron
10
Lee, Francis
9
Vyas, Dolatrai
8
Kadow, John
5
Wild, Robert
4
Vite, Gregory
3
Wall, Monroe
3
Wani, Mansukh
3
Wittman, Mark
3
Soejarto, Doel
3
Wu, Mu-Jen
3
manne, swam
3
Farnsworth, Norman
3
Balasubramanian, Balu
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Geonetwork of William Rose (preview)
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All Publications
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2007: Phifer Sharnelle S; Lee Dongho; Seo Eun-Kyoung; Kim Nam-Cheol; Graf Tyler N; Kroll David J; Navarro Hernan A; Izydore Robert A; Jiménez Francisco; Garcia Ricardo; Rose William C; Fairchild Craig R; Wild Robert; Soejarto Djaja D; Farnsworth Norman R; Kinghorn A Douglas; Oberlies Nicholas H; Wall Monroe E; Wani Mansukh C
Alvaradoins E-N, antitumor and cytotoxic anthracenone C-glycosides from the leaves of Alvaradoa haitiensis.
Journal of natural products 2007;70(6):954-61.
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2006: Rose William C; Marathe Punit H; Jang Graham R; Monticello Thomas M; Balasubramanian Balu N; Long Byron; Fairchild Craig R; Wall Monroe E; Wani Mansukh C
Novel fluoro-substituted camptothecins: in vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization.
Cancer chemotherapy and pharmacology 2006;58(1):73-85.
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2006: Soejarto Djaja Doel; Zhang Hong Jie; Fong Harry H S; Tan Ghee T; Ma Cui Ying; Gyllenhaal Charlotte; Riley Mary C; Kadushin Marian R; Franzblau Scott G; Bich Truong Quang; Cuong Nguyen Manh; Hiep Nguyen Tien; Loc Phan Ke; Xuan Le Thi; Hai Nong Van; Hung Nguyen Van; Chien Nguyen Quyet; Binh Le Tran; Vu Bui Minh; Ly Ho Minh; Southavong Bounhong; Sydara Kongmany; Bouamanivong S; Pezzuto John M; Rose William C; Dietzman Gregg R; Miller Byron E; Thuy Tran Van
"Studies on biodiversity of Vietnam and Laos" 1998-2005: examining the impact.
Journal of natural products 2006;69(3):473-81.
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2006: Wild Robert; Fager Krista; Flefleh Christine; Kan David; Inigo Ivan; Castaneda Stephen; Luo Feng Roger; Camuso Amy; McGlinchey Kelly; Rose William C
Cetuximab preclinical antitumor activity (monotherapy and combination based) is not predicted by relative total or activated epidermal growth factor receptor tumor expression levels.
Molecular cancer therapeutics 2006;5(1):104-13.
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2005: Luo F R; Yang Z; Dong H; Camuso A; McGlinchey K; Fager K; Flefleh C; Kan D; Inigo I; Castaneda S; Rose W C; Kramer R A; Wild R; Lee F Y
Correlation of pharmacokinetics with the antitumor activity of Cetuximab in nude mice bearing the GEO human colon carcinoma xenograft.
Cancer chemotherapy and pharmacology 2005;56(5):455-64.
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2005: Soejarto D D; Fong H H S; Tan G T; Zhang H J; Ma C Y; Franzblau S G; Gyllenhaal C; Riley M C; Kadushin M R; Pezzuto J M; Xuan L T; Hiep N T; Hung N V; Vu B M; Loc P K; Dac L X; Binh L T; Chien N Q; Hai N V; Bich T Q; Cuong N M; Southavong B; Sydara K; Bouamanivong S; Ly H M; Thuy Tran Van; Rose W C; Dietzman G R
Ethnobotany/ethnopharmacology and mass bioprospecting: issues on intellectual property and benefit-sharing.
Journal of ethnopharmacology 2005;100(1-2):15-22.
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2005: Saulnier Mark G; Balasubramanian Balu N; Long Byron H; Frennesson David B; Ruediger Edward; Zimmermann Kurt; Eummer Jeffrey T; St Laurent Denis R; Stoffan Karen M; Naidu B Narasimhulu; Mahler Mikael; Beaulieu Francis; Bachand Carol; Lee Frank Y; Fairchild Craig R; Stadnick Linda K; Rose William C; Solomon Carola; Wong Henry; Martel Alain; Wright John J; Kramer Robert; Langley David R; Vyas Dolatrai M
Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11.
Journal of medicinal chemistry 2005;48(7):2258-61.
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2004: Rose William C; Wild Robert
Therapeutic synergy of oral taxane BMS-275183 and cetuximab versus human tumor xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(21):7413-7.
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2004: Hwang Bang Yeon; Su Bao-Ning; Chai Heebyung; Mi Qiuwen; Kardono Leonardus B S; Afriastini Johar J; Riswan Soedarsono; Santarsiero Bernard D; Mesecar Andrew D; Wild Robert; Fairchild Craig R; Vite Gregory D; Rose William C; Farnsworth Norman R; Cordell Geoffrey A; Pezzuto John M; Swanson Steven M; Kinghorn A Douglas
Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris.
The Journal of organic chemistry 2004;69(10):3350-8.
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2004: Tarrant James G; Cook Donald; Fairchild Craig; Kadow John F; Long Byron H; Rose William C; Vyas Dolatrai
Synthesis and biological activity of macrocyclic taxane analogues.
Bioorganic & medicinal chemistry letters 2004;14(10):2555-8.
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2004: Balasubramanian Balu N; St Laurent Denis R; Saulnier Mark G; Long Byron H; Bachand Carol; Beaulieu Francis; Clarke Wendy; Deshpande Milind; Eummer Jeffrey; Fairchild Craig R; Frennesson David B; Kramer Robert; Lee Frank Y; Mahler Mikael; Martel Alain; Naidu B Narasimhulu; Rose William C; Russell John; Ruediger Edward; Solomon Carola; Stoffan Karen M; Wong Henry; Wright John J; Zimmermann Kurt; Vyas Dolatrai M
Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents. Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-beta-D-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor model.
Journal of medicinal chemistry 2004;47(7):1609-12.
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2003: Mastalerz Harold; Cook Donald; Fairchild Craig R; Hansel Steven; Johnson Walter; Kadow John F; Long Byron H; Rose William C; Tarrant James; Wu Mu-Jen; Xue May Quifen; Zhang Guifen; Zoeckler Mary; Vyas Dolatrai M
The discovery of BMS-275183: an orally efficacious novel taxane.
Bioorganic & medicinal chemistry 2003;11(20):4315-23.
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2002: Long Byron H; Rose William C; Vyas Dolatrai M; Matson James A; Forenza Salvatore
Discovery of antitumor indolocarbazoles: rebeccamycin, NSC 655649, and fluoroindolocarbazoles.
Current medicinal chemistry. Anti-cancer agents 2002;2(2):255-66.
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2002: Seo Eun-Kyoung; Kim Nam-Cheol; Wani Mansukh C; Wall Monroe E; Navarro Hernán A; Burgess Jason P; Kawanishi Kazuko; Kardono Leonardus B S; Riswan Soedarsono; Rose William C; Fairchild Craig R; Farnsworth Norman R; Kinghorn A Douglas
Cytotoxic prenylated xanthones and the unusual compounds anthraquinobenzophenones from Cratoxylum sumatranum.
Journal of natural products 2002;65(3):299-305.
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2001: Altstadt T J; Fairchild C R; Golik J; Johnston K A; Kadow J F; Lee F Y; Long B H; Rose W C; Vyas D M; Wong H; Wu M J; Wittman M D
Synthesis and antitumor activity of novel C-7 paclitaxel ethers: discovery of BMS-184476.
Journal of medicinal chemistry 2001;44(26):4577-83.
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2001: Rose W C; Lee F Y; Fairchild C R; Lynch M; Monticello T; Kramer R A; Manne V
Preclinical antitumor activity of BMS-214662, a highly apoptotic and novel farnesyltransferase inhibitor.
Cancer research 2001;61(20):7507-17.
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2001: Rose W C; Long B H; Fairchild C R; Lee F Y; Kadow J F
Preclinical pharmacology of BMS-275183, an orally active taxane.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):2016-21.
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2001: Lee F Y; Borzilleri R; Fairchild C R; Kim S H; Long B H; Reventos-Suarez C; Vite G D; Rose W C; Kramer R A
BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(5):1429-37.
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2001: Wittman M D; Kadow J F; Vyas D M; Lee F L; Rose W C; Long B H; Fairchild C; Johnston K
Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids.
Bioorganic & medicinal chemistry letters 2001;11(6):811-4.
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2001: Wittman M D; Altstadt T J; Fairchild C; Hansel S; Johnston K; Kadow J F; Long B H; Rose W C; Vyas D M; Wu M J; Zoeckler M E
Synthesis of metabolically blocked paclitaxel analogues.
Bioorganic & medicinal chemistry letters 2001;11(6):809-10.
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2001: Lam K S; Schroeder D R; Veitch J M; Colson K L; Matson J A; Rose W C; Doyle T W; Forenza S
Production, isolation and structure determination of novel fluoroindolocarbazoles from Saccharothrix aerocolonigenes ATCC 39243.
The Journal of antibiotics 2001;54(1):1-9.
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2001: Rose W C; Fairchild C; Lee F Y
Preclinical antitumor activity of two novel taxanes.
Cancer chemotherapy and pharmacology 2001;47(2):97-105.
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2000: Hunt J T; Ding C Z; Batorsky R; Bednarz M; Bhide R; Cho Y; Chong S; Chao S; Gullo-Brown J; Guo P; Kim S H; Lee F Y; Leftheris K; Miller A; Mitt T; Patel M; Penhallow B A; Ricca C; Rose W C; Schmidt R; Slusarchyk W A; Vite G; Manne V
Discovery of (R)-7-cyano-2,3,4, 5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a farnesyltransferase inhibitor with potent preclinical antitumor activity.
Journal of medicinal chemistry 2000;43(20):3587-95.
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2000: Xue M; Long B H; Fairchild C; Johnston K; Rose W C; Kadow J F; Vyas D M; Chen S H
Structure-activity relationships study at the 3'-N position of paclitaxel. Part 2: synthesis and biological evaluation of 3'-N-thiourea- and 3'-N-thiocarbamate-bearing paclitaxel analogues.
Bioorganic & medicinal chemistry letters 2000;10(12):1327-31.
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2000: Rose W C; Lee F Y; Golik J; Kadow J
Preclinical oral antitumor activity of BMS-185660, a paclitaxel derivative.
Cancer chemotherapy and pharmacology 2000;46(3):246-50.
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1999: Ding C Z; Batorsky R; Bhide R; Chao H J; Cho Y; Chong S; Gullo-Brown J; Guo P; Kim S H; Lee F; Leftheris K; Miller A; Mitt T; Patel M; Penhallow B A; Ricca C; Rose W C; Schmidt R; Slusarchyk W A; Vite G; Yan N; Manne V; Hunt J T
Discovery and structure-activity relationships of imidazole-containing tetrahydrobenzodiazepine inhibitors of farnesyltransferase.
Journal of medicinal chemistry 1999;42(25):5241-53.
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1997: Chordia M D; Kingston D G; Hamel E; Lin C M; Long B H; Fairchild C A; Johnston K A; Rose W C
Synthesis and biological activity of A-nor-paclitaxel analogues.
Bioorganic & medicinal chemistry 1997;5(5):941-7.
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1997: Rose W C
Combination chemotherapy involving orally administered etoposide and JM-216 in murine tumor models.
Cancer chemotherapy and pharmacology 1997;40(1):51-6.
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1997: Rose W C; Clark J L; Lee F Y; Casazza A M
Preclinical antitumor activity of water-soluble paclitaxel derivatives.
Cancer chemotherapy and pharmacology 1997;39(6):486-92.
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1995: Lam K S; Veitch J A; Golik J; Rose W C; Doyle T W; Forenza S
Production and isolation of two novel esperamicins in a chemically defined medium.
The Journal of antibiotics 1995;48(12):1497-501.
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1995: Lam K S; Gustavson D R; Hesler G A; Dabrah T T; Matson J A; Berry R L; Rose W C; Forenza S
Korkormicins, novel depsipeptide antitumor antibiotics from Micromonospora sp C39500: fermentation, precursor directed biosynthesis and biological activities.
Journal of industrial microbiology 1995;15(1):60-5.
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1993: Mayerl F; Gao Q; Huang S; Klohr S E; Matson J A; Gustavson D R; Pirnik D M; Berry R L; Fairchild C; Rose W C
Eupenifeldin, a novel cytotoxic bistropolone from Eupenicillium brefeldianum.
The Journal of antibiotics 1993;46(7):1082-8.
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1993: Rose W C; Crosswell A R; Schurig J E; Casazza A M
Preclinical antitumor activity of orally administered platinum (IV) complexes.
Cancer chemotherapy and pharmacology 1993;32(3):197-203.
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1992: Bradner W T; Catino J J; Long B H; Rose W C; Schurig J E
Experimental tumor inhibitory and toxic properties of the mitomycin A analogue 7-(2-hydroxyethoxy) mitosane (BMY-25551).
Anticancer research 1992;12(3):959-64.
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1990: Rose W C; Basler G A
In vivo model development of cisplatin-resistant and -sensitive A2780 human ovarian carcinomas.
In vivo (Athens, Greece) 1990;4(6):391-6.
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1990: Rose W C; Crosswell A R; Bronson J J; Martin J C
In vivo antitumor activity of 9-[(2-phosphonylmethoxy)ethyl]-guanine and related phosphonate nucleotide analogues.
Journal of the National Cancer Institute 1990;82(6):510-2.
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1990: Schurig J E; Rose W C; Kamei H; Nishiyama Y; Bradner W T; Stringfellow D A
Experimental antitumor activity of BMY-28175 a new fermentation derived antitumor agent.
Investigational new drugs 1990;8(1):7-15.
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1990: Kaneko T; Wong H; Rose W C; Bradner W T; Doyle T W
Cyclic acetal derivatives of mitomycin C.
The Journal of antibiotics 1990;43(1):122-4.
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1990: Rose W C; Basler G A; Trail P A; Saulnier M; Crosswell A R; Casazza A M
Preclinical antitumor activity of a soluble etoposide analog, BMY-40481-30.
Investigational new drugs 1990;8 Suppl 1():S25-32.
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1990: Bradner W T; Rose W C; Schurig J E; Florczyk A P
Antitumor activity and toxicity in animals of N-7[2-(4-nitrophenyldithio) ethyl] mitomycin C (BMY-25067).
Investigational new drugs 1990;8 Suppl 1():S1-7.
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1989: Matson J A; Rose W C; Bush J A; Myllymaki R; Bradner W T; Doyle T W
Antitumor activity of chrysomycins M and V.
The Journal of antibiotics 1989;42(9):1446-8.
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1989: Trail P A; Rose W C
Development of a human xenograft model for the evaluation of monoclonal antibody L6-mitomycin immunoconjugates.
In vivo (Athens, Greece) 1989;3(5):319-24.
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1989: Schurig J E; Bradner W T; Basler G A; Rose W C
Experimental antitumor activity of BMY-28090, a new antitumor antibiotic.
Investigational new drugs 1989;7(2-3):173-8.
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1989: Vyas D M; Benigni D; Rose W C; Bradner W T; Doyle T W
Synthesis and in vivo antitumor activity of novel mitomycin A disulfide analogs.
The Journal of antibiotics 1989;42(7):1199-201.
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1989: Saulnier M G; Vyas D M; Langley D R; Doyle T W; Rose W C; Crosswell A R; Long B H
E-ring desoxy analogues of etoposide.
Journal of medicinal chemistry 1989;32(7):1418-20.
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1989: Rose W C; Basler G A
An in vivo human tumor xenograft model of etoposide resistance.
In vivo (Athens, Greece) 1989;3(4):249-53.
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1988: Rose W C; Schurig J E; Meeker J B
Correlation of in vitro cytotoxicity with preclinical in vivo antitumor activity.
Anticancer research 1988;8(3):355-67.
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1987: Rose W C; Huftalen J B; Bradner W T; Schurig J E
In vivo characterization of P388 leukemia resistant to mitomycin C.
In vivo (Athens, Greece) 1987;1(1):47-52.
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1985: Bradner W T; Rose W C; Schurig J E; Florczyk A P; Huftalen J B; Catino J J
Antitumor activity and toxicity in animals of BMY-25282, a new mitomycin derivative.
Cancer research 1985;45(12 Pt 1):6475-81.
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1985: Rose W C; Schurig J E
Preclinical antitumor and toxicologic profile of carboplatin.
Cancer treatment reviews 1985;12 Suppl A():1-19.
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1985: Kaneko T; Wong H; Howell H G; Rose W C; Bradner W T; Doyle T W
Reductive amination of 3-ketoanguidin and antitumor activity of the products.
Journal of medicinal chemistry 1985;28(7):958-60.
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1985: Kaneko T; Wong H; Doyle T W; Rose W C; Bradner W T
Bicyclic and tricyclic analogues of anthramycin.
Journal of medicinal chemistry 1985;28(3):388-92.
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1984: Bradner W T; Rose W C; Schurig J E; Schlein A; Huftalen J B
Antitumor activity and toxicity in animals of RR-150 (7-cysteaminomitosane), a new mitomycin derivative.
Cancer research 1984;44(12 Pt 1):5619-23.
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1984: Rose W C; Reed F C; Siminoff P; Bradner W T
Immunotherapy of Madison 109 lung carcinoma and other murine tumors using lentinan.
Cancer research 1984;44(4):1368-73.
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1984: Schurig J E; Rose W C; Hirth R S; Schlein A; Huftalen J B; Florczyk A P; Bradner W T
Tallysomycin S10b: experimental antitumor activity and toxicity.
Cancer chemotherapy and pharmacology 1984;13(3):164-70.
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1983: Rose W C; Schurig J E; Huftalen J B; Bradner W T
Experimental antitumor activity and toxicity of a new chemotherapeutic agent, BBM 928A.
Cancer research 1983;43(4):1504-10.
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1982: Schurig J E; Florczyk A P; Rose W C; Bradner W T
Antiemetic activity of butorphanol against cisplatin-induced emesis in ferrets and dogs.
Cancer treatment reports 1982;66(10):1831-5.
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1982: Rose W C; Schurig J E; Huftalen J B; Bradner W T
Antitumor activity and toxicity of cisplatin analogs.
Cancer treatment reports 1982;66(1):135-46.
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