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Steven Rosen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
25
Singer, Mark
18
Hemmerich, Stefan
11
Lasky, Laurence
10
Bertozzi, Carolyn
10
Bistrup, Annette
7
van Zante, Annemieke
6
Tangemann, K
6
Lee, Jin Kyu
6
Tsay, Durwin
6
Uchimura, Kenji
5
Bhakta, S
4
Giblin, PA
4
Leffler, Hakon
4
Morimoto-Tomita, Megumi
4
Stoolman, Lloyd

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Publications

TOP 3
Tang Renhong; Rosen Steven D
Functional consequences of the subdomain organization of the sulfs.
Rosen Steven D; Arata-Kawai Hanayo
"Home sweet home" for lymphocytes.
Kerr Sheena C; Fieger Claudia B; Snapp Karen R; Rosen Steven D
Endoglycan, a member of the CD34 family of sialomucins, is a ligand for the vascular selectins.

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All Publications

2009: Tang Renhong; Rosen Steven D
Functional consequences of the subdomain organization of the sulfs.
The Journal of biological chemistry 2009;284(32):21505-14.
2009: Rosen Steven D; Arata-Kawai Hanayo
"Home sweet home" for lymphocytes.
Blood 2009;114(3):499-500.
2008: Kerr Sheena C; Fieger Claudia B; Snapp Karen R; Rosen Steven D
Endoglycan, a member of the CD34 family of sialomucins, is a ligand for the vascular selectins.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1480-90.
2008: Kanda Hidenobu; Newton Rebecca; Klein Russell; Morita Yuka; Gunn Michael D; Rosen Steven D
Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs.
Nature immunology 2008;9(4):415-23.
2007: Nawroth Roman; van Zante Annemieke; Cervantes Sara; McManus Michael; Hebrok Matthias; Rosen Steven D
Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells.
PloS one 2007;2(4):e392.
2006: Uchimura Kenji; Rosen Steven D
Sulfated L-selectin ligands as a therapeutic target in chronic inflammation.
Trends in immunology 2006;27(12):559-65.
2006: Rosen Steven D
Homing in on L-selectin.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):3-4.
2006: Uchimura Kenji; Morimoto-Tomita Megumi; Rosen Steven D
Measuring the activities of the Sulfs: two novel heparin/heparan sulfate endosulfatases.
Methods in enzymology 2006;416():243-53.
2006: Yang Jiwei; Rosen Steven D; Bendele Philip; Hemmerich Stefan
Induction of PNAd and N-acetylglucosamine 6-O-sulfotransferases 1 and 2 in mouse collagen-induced arthritis.
BMC immunology 2006;7():12.
2006: Uchimura Kenji; Morimoto-Tomita Megumi; Bistrup Annette; Li Jessica; Lyon Malcolm; Gallagher John; Werb Zena; Rosen Steven D
HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.
BMC biochemistry 2006;7():2.
2005: Morimoto-Tomita Megumi; Uchimura Kenji; Bistrup Annette; Lum David H; Egeblad Mikala; Boudreau Nancy; Werb Zena; Rosen Steven D
Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer.
Neoplasia (New York, N.Y.) 2005;7(11):1001-10.
2005: Uchimura Kenji; Gauguet Jean-Marc; Singer Mark S; Tsay Durwin; Kannagi Reiji; Muramatsu Takashi; von Andrian Ulrich H; Rosen Steven D
A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules.
Nature immunology 2005;6(11):1105-13.
2005: Saad Ola M; Ebel Heiner; Uchimura Kenji; Rosen Steven D; Bertozzi Carolyn R; Leary Julie A
Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase.
Glycobiology 2005;15(8):818-26.
2005: Rosen Steven D; Tsay Durwin; Singer Mark S; Hemmerich Stefan; Abraham William M
Therapeutic targeting of endothelial ligands for L-selectin (PNAd) in a sheep model of asthma.
The American journal of pathology 2005;166(3):935-44.
2005: Pablos José L; Santiago Begoña; Tsay Durwin; Singer Mark S; Palao Guillermo; Galindo María; Rosen Steven D
A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells.
BMC immunology 2005;6(1):6.
2004: Gauguet Jean-Marc; Rosen Steven D; Marth Jamey D; von Andrian Ulrich H
Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial cell N-acetylglucosamine-6-sulfotransferase exert differential control over B- and T-lymphocyte homing to peripheral lymph nodes.
Blood 2004;104(13):4104-12.
2004: Bistrup Annette; Tsay Durwin; Shenoy Priti; Singer Mark S; Bangia Naveen; Luther Sanjiv A; Cyster Jason G; Ruddle Nancy H; Rosen Steven D
Detection of a sulfotransferase (HEC-GlcNAc6ST) in high endothelial venules of lymph nodes and in high endothelial venule-like vessels within ectopic lymphoid aggregates: relationship to the MECA-79 epitope.
The American journal of pathology 2004;164(5):1635-44.
2004: Palmeri Diana; Zuo Feng-Rong; Rosen Steven D; Hemmerich Stefan
Differential gene expression profile of human tonsil high endothelial cells: implications for lymphocyte trafficking.
Journal of leukocyte biology 2004;75(5):910-27.
2004: Sarangapani Krishna K; Yago Tadayuki; Klopocki Arkadiusz G; Lawrence Michael B; Fieger Claudia B; Rosen Steven D; McEver Rodger P; Zhu Cheng
Low force decelerates L-selectin dissociation from P-selectin glycoprotein ligand-1 and endoglycan.
The Journal of biological chemistry 2004;279(3):2291-8.
2004: Rosen Steven D
Ligands for L-selectin: homing, inflammation, and beyond.
Annual review of immunology 2004;22():129-56.
2003: van Zante Annemieke; Gauguet Jean-Marc; Bistrup Annette; Tsay Durwin; von Andrian Ulrich H; Rosen Steven D
Lymphocyte-HEV interactions in lymph nodes of a sulfotransferase-deficient mouse.
The Journal of experimental medicine 2003;198(9):1289-300.
2003: Tjoa Tjoson; Strausbaugh Holly J; Maida Nino; Dazin Paul F; Rosen Steven D; Noble-Haeusslein Linda J
The use of flow cytometry to assess neutrophil infiltration in the injured murine spinal cord.
Journal of neuroscience methods 2003;129(1):49-59.
2003: Fieger Claudia B; Sassetti Christopher M; Rosen Steven D
Endoglycan, a member of the CD34 family, functions as an L-selectin ligand through modification with tyrosine sulfation and sialyl Lewis x.
The Journal of biological chemistry 2003;278(30):27390-8.
2003: van Zante A; Rosen S D
Sulphated endothelial ligands for L-selectin in lymphocyte homing and inflammation.
Biochemical Society transactions 2003;31(2):313-7.
2003: Lee Jin Kyu; Bistrup Annette; van Zante Annemieke; Rosen Steven D
Activities and expression pattern of the carbohydrate sulfotransferase GlcNAc6ST-3 (I-GlcNAc6ST): functional implications.
Glycobiology 2003;13(4):245-54.
2003: Genbacev Olga D; Prakobphol Akraporn; Foulk Russell A; Krtolica Ana R; Ilic Dusko; Singer Mark S; Yang Zhi-Qiang; Kiessling Laura L; Rosen Steven D; Fisher Susan J
Trophoblast L-selectin-mediated adhesion at the maternal-fetal interface.
Science (New York, N.Y.) 2003;299(5605):405-8.
2002: Morimoto-Tomita Megumi; Uchimura Kenji; Werb Zena; Hemmerich Stefan; Rosen Steven D
Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans.
The Journal of biological chemistry 2002;277(51):49175-85.
2001: Hemmerich S; Bistrup A; Singer M S; van Zante A; Lee J K; Tsay D; Peters M; Carminati J L; Brennan T J; Carver-Moore K; Leviten M; Fuentes M E; Ruddle N H; Rosen S D
Sulfation of L-selectin ligands by an HEV-restricted sulfotransferase regulates lymphocyte homing to lymph nodes.
Immunity 2001;15(2):237-47.
2001: Bruehl R E; Dasgupta F; Katsumoto T R; Tan J H; Bertozzi C R; Spevak W; Ahn D J; Rosen S D; Nagy J O
Polymerized liposome assemblies: bifunctional macromolecular selectin inhibitors mimicking physiological selectin ligands.
Biochemistry 2001;40(20):5964-74.
2001: Strausbaugh H J; Rosen S D
A potential role for annexin 1 as a physiologic mediator of glucocorticoid-induced L-selectin shedding from myeloid cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):6294-300.
2001: Hemmerich S; Lee J K; Bhakta S; Bistrup A; Ruddle N R; Rosen S D
Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family.
Glycobiology 2001;11(1):75-87.
2000: Bhakta S; Bartes A; Bowman K G; Kao W M; Polsky I; Lee J K; Cook B N; Bruehl R E; Rosen S D; Bertozzi C R; Hemmerich S
Sulfation of N-acetylglucosamine by chondroitin 6-sulfotransferase 2 (GST-5).
The Journal of biological chemistry 2000;275(51):40226-34.
2000: Bruehl R E; Bertozzi C R; Rosen S D
Minimal sulfated carbohydrates for recognition by L-selectin and the MECA-79 antibody.
The Journal of biological chemistry 2000;275(42):32642-8.
2000: Hemmerich S; Rosen S D
Carbohydrate sulfotransferases in lymphocyte homing.
Glycobiology 2000;10(9):849-56.
2000: Palmeri D; van Zante A; Huang C C; Hemmerich S; Rosen S D
Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells.
The Journal of biological chemistry 2000;275(25):19139-45.
2000: Sassetti C; Van Zante A; Rosen S D
Identification of endoglycan, a member of the CD34/podocalyxin family of sialomucins.
The Journal of biological chemistry 2000;275(12):9001-10.
1999: Tangemann K; Bistrup A; Hemmerich S; Rosen S D
Sulfation of a high endothelial venule-expressed ligand for L-selectin. Effects on tethering and rolling of lymphocytes.
The Journal of experimental medicine 1999;190(7):935-42.
1999: Lee J K; Bhakta S; Rosen S D; Hemmerich S
Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue.
Biochemical and biophysical research communications 1999;263(2):543-9.
1999: Strausbaugh H J; Green P G; Lo E; Tangemann K; Reichling D B; Rosen S D; Levine J D
Painful stimulation suppresses joint inflammation by inducing shedding of L-selectin from neutrophils.
Nature medicine 1999;5(9):1057-61.
1999: Papadopoulos E J; Sassetti C; Saeki H; Yamada N; Kawamura T; Fitzhugh D J; Saraf M A; Schall T; Blauvelt A; Rosen S D; Hwang S T
Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation.
European journal of immunology 1999;29(8):2551-9.
1999: Prakobphol A; Tangemann K; Rosen S D; Hoover C I; Leffler H; Fisher S J
Separate oligosaccharide determinants mediate interactions of the low-molecular-weight salivary mucin with neutrophils and bacteria.
Biochemistry 1999;38(21):6817-25.
1999: Bistrup A; Bhakta S; Lee J K; Belov Y Y; Gunn M D; Zuo F R; Huang C C; Kannagi R; Rosen S D; Hemmerich S
Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin.
The Journal of cell biology 1999;145(4):899-910.
1998: Tangemann K; Gunn M D; Giblin P; Rosen S D
A high endothelial cell-derived chemokine induces rapid, efficient, and subset-selective arrest of rolling T lymphocytes on a reconstituted endothelial substrate.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):6330-7.
1998: Bowman K G; Hemmerich S; Bhakta S; Singer M S; Bistrup A; Rosen S D; Bertozzi C R
Identification of an N-acetylglucosamine-6-0-sulfotransferase activity specific to lymphoid tissue: an enzyme with a possible role in lymphocyte homing.
Chemistry & biology 1998;5(8):447-60.
1998: Sassetti C; Tangemann K; Singer M S; Kershaw D B; Rosen S D
Identification of podocalyxin-like protein as a high endothelial venule ligand for L-selectin: parallels to CD34.
The Journal of experimental medicine 1998;187(12):1965-75.
1998: Prakobphol A; Thomsson K A; Hansson G C; Rosen S D; Singer M S; Phillips N J; Medzihradszky K F; Burlingame A L; Leffler H; Fisher S J
Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity.
Biochemistry 1998;37(14):4916-27.
1998: Gunn M D; Tangemann K; Tam C; Cyster J G; Rosen S D; Williams L T
A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(1):258-63.
1997: Giblin P A; Hwang S T; Katsumoto T R; Rosen S D
Ligation of L-selectin on T lymphocytes activates beta1 integrins and promotes adhesion to fibronectin.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3498-507.
1997: Rosen S D; Hwang S T; Giblin P A; Singer M S
High-endothelial-venule ligands for L-selectin: identification and functions.
Biochemical Society transactions 1997;25(2):428-33.
1997: Bertozzi C R; Singer M S; Rosen S D
An ELISA for selectins based on binding to a physiological ligand.
Journal of immunological methods 1997;203(2):157-65.
1996: Hwang S T; Singer M S; Giblin P A; Yednock T A; Bacon K B; Simon S I; Rosen S D
GlyCAM-1, a physiologic ligand for L-selectin, activates beta 2 integrins on naive peripheral lymphocytes.
The Journal of experimental medicine 1996;184(4):1343-8.
1996: Singer M S; Rosen S D
Purification and quantification of L-selectin-reactive GlyCAM-1 from mouse serum.
Journal of immunological methods 1996;196(2):153-61.
1996: Rosen S D; Bertozzi C R
Two selectins converge on sulphate. Leukocyte adhesion.
Current biology : CB 1996;6(3):261-4.
1996: Mallett S; Rosen S D; Hyun W
Calcium-dependent lectin activity with novel distribution on thymocyte subsets.
European journal of immunology 1996;26(1):77-83.
1996: Onrust S V; Hartl P M; Rosen S D; Hanahan D
Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice.
The Journal of clinical investigation 1996;97(1):54-64.
1995: Bertozzi C R; Fukuda S; Rosen S D
Sulfated disaccharide inhibitors of L-selectin: deriving structural leads from a physiological selectin ligand.
Biochemistry 1995;34(44):14271-8.
1995: Crommie D; Rosen S D
Biosynthesis of GlyCAM-1, a mucin-like ligand for L-selectin.
The Journal of biological chemistry 1995;270(38):22614-24.
1995: Hemmerich S; Leffler H; Rosen S D
Structure of the O-glycans in GlyCAM-1, an endothelial-derived ligand for L-selectin.
The Journal of biological chemistry 1995;270(20):12035-47.
1994: Hemmerich S; Butcher E C; Rosen S D
Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibody.
The Journal of experimental medicine 1994;180(6):2219-26.
1994: Rosen S D; Bertozzi C R
The selectins and their ligands.
Current opinion in cell biology 1994;6(5):663-73.
1994: Huang K; Kikuta A; Rosen S D
Myelin localization of a central nervous system ligand for L-selectin.
Journal of neuroimmunology 1994;53(2):133-41.
1994: Hemmerich S; Rosen S D
6'-sulfated sialyl Lewis x is a major capping group of GlyCAM-1.
Biochemistry 1994;33(16):4830-5.
1994: Hemmerich S; Bertozzi C R; Leffler H; Rosen S D
Identification of the sulfated monosaccharides of GlyCAM-1, an endothelial-derived ligand for L-selectin.
Biochemistry 1994;33(16):4820-9.
1993: Rosen S D
Ligands for L-selectin: where and how many?
Research in immunology 1993;144(9):699-703; discussion 754-62.
1993: Baumheter S; Singer M S; Henzel W; Hemmerich S; Renz M; Rosen S D; Lasky L A
Binding of L-selectin to the vascular sialomucin CD34.
Science (New York, N.Y.) 1993;262(5132):436-8.
1993: Rosen S D
Robert Feulgen Lecture 1993. L-selectin and its biological ligands.
Histochemistry 1993;100(3):185-91.
1993: Rosen S D
Cell surface lectins in the immune system.
Seminars in immunology 1993;5(4):237-47.
1993: Imai Y; Rosen S D
Direct demonstration of heterogeneous, sulfated O-linked carbohydrate chains on an endothelial ligand for L-selectin.
Glycoconjugate journal 1993;10(1):34-9.
1993: Imai Y; Lasky L A; Rosen S D
Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectin.
Nature 1993;361(6412):555-7.
1992: Imai Y; Lasky L A; Rosen S D
Further characterization of the interaction between L-selectin and its endothelial ligands.
Glycobiology 1992;2(4):373-81.
1992: Lasky L A; Singer M S; Dowbenko D; Imai Y; Henzel W J; Grimley C; Fennie C; Gillett N; Watson S R; Rosen S D
An endothelial ligand for L-selectin is a novel mucin-like molecule.
Cell 1992;69(6):927-38.
1992: Lasky L A; Singer M S; Dowbenko D; Imai Y; Henzel W; Fennie C; Watson S; Rosen S D
Glycosylation-dependent cell adhesion molecule 1: a novel mucin-like adhesion ligand for L-selectin.
Cold Spring Harbor symposia on quantitative biology 1992;57():259-69.
1991: Huang K; Geoffroy J S; Singer M S; Rosen S D
A lymphocyte homing receptor (L-selectin) mediates the in vitro attachment of lymphocytes to myelinated tracts of the central nervous system.
The Journal of clinical investigation 1991;88(5):1778-83.
1991: Watson S R; Imai Y; Fennie C; Geoffrey J; Singer M; Rosen S D; Lasky L A
The complement binding-like domains of the murine homing receptor facilitate lectin activity.
The Journal of cell biology 1991;115(1):235-43.
1991: Ley K; Gaehtgens P; Fennie C; Singer M S; Lasky L A; Rosen S D
Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo.
Blood 1991;77(12):2553-5.
1991: Imai Y; Singer M S; Fennie C; Lasky L A; Rosen S D
Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor.
The Journal of cell biology 1991;113(5):1213-21.
1990: True D D; Singer M S; Lasky L A; Rosen S D
Requirement for sialic acid on the endothelial ligand of a lymphocyte homing receptor.
The Journal of cell biology 1990;111(6 Pt 1):2757-64.
1990: Rosen S D
The LEC-CAMs: an emerging family of cell-cell adhesion receptors based upon carbohydrate recognition.
American journal of respiratory cell and molecular biology 1990;3(5):397-402.
1990: Corral L; Singer M S; Macher B A; Rosen S D
Requirement for sialic acid on neutrophils in a GMP-140 (PADGEM) mediated adhesive interaction with activated platelets.
Biochemical and biophysical research communications 1990;172(3):1349-56.
1990: Imai Y; True D D; Singer M S; Rosen S D
Direct demonstration of the lectin activity of gp90MEL, a lymphocyte homing receptor.
The Journal of cell biology 1990;111(3):1225-32.
1990: Watson S R; Imai Y; Fennie C; Geoffroy J S; Rosen S D; Lasky L A
A homing receptor-IgG chimera as a probe for adhesive ligands of lymph node high endothelial venules.
The Journal of cell biology 1990;110(6):2221-9.
1989: Geoffroy J S; Rosen S D
Demonstration that a lectin-like receptor (gp90MEL) directly mediates adhesion of lymphocytes to high endothelial venules of lymph nodes.
The Journal of cell biology 1989;109(5):2463-9.
1989: Rosen S D
Lymphocyte homing: progress and prospects.
Current opinion in cell biology 1989;1(5):913-9.
1989: Rosen S D; Chi S I; True D D; Singer M S; Yednock T A
Intravenously injected sialidase inactivates attachment sites for lymphocytes on high endothelial venules.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(6):1895-902.
1989: Lasky L A; Singer M S; Yednock T A; Dowbenko D; Fennie C; Rodriguez H; Nguyen T; Stachel S; Rosen S D
Cloning of a lymphocyte homing receptor reveals a lectin domain.
Cell 1989;56(6):1045-55.
1989: Yednock T A; Rosen S D
Lymphocyte homing.
Advances in immunology 1989;44():313-78.
1987: Stoolman L M; Yednock T A; Rosen S D
Homing receptors on human and rodent lymphocytes--evidence for a conserved carbohydrate-binding specificity.
Blood 1987;70(6):1842-50.
1987: Yednock T A; Butcher E C; Stoolman L M; Rosen S D
Receptors involved in lymphocyte homing: relationship between a carbohydrate-binding receptor and the MEL-14 antigen.
The Journal of cell biology 1987;104(3):725-31.
1987: Yednock T A; Stoolman L M; Rosen S D
Phosphomannosyl-derivatized beads detect a receptor involved in lymphocyte homing.
The Journal of cell biology 1987;104(3):713-23.
1985: Rosen S D; Singer M S; Yednock T A; Stoolman L M
Involvement of sialic acid on endothelial cells in organ-specific lymphocyte recirculation.
Science (New York, N.Y.) 1985;228(4702):1005-7.

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