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Ivan Rosenberg

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Dominik Rejman; Pavel Klener; Bokang Maswabi; Natalya Panova; Radek Pohl; Ivan Rosenberg
N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase.
Anna Ligasová; Ivan Rosenberg; Dmytro Strunin; Radek Liboska; Karel Koberna
Atomic scissors: a new method of tracking the 5-bromo-2'-deoxyuridine-labeled DNA in situ.
Radek Liboska; Anna Ligasová; Ivan Rosenberg; Dmytro Strunin; Karel Koberna
Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity.

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All Publications

2012: Dominik Rejman; Pavel Klener; Bokang Maswabi; Natalya Panova; Radek Pohl; Ivan Rosenberg
N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase.
Journal of medicinal chemistry 2012;55(4):1612-21.
2012: Anna Ligasová; Ivan Rosenberg; Dmytro Strunin; Radek Liboska; Karel Koberna
Atomic scissors: a new method of tracking the 5-bromo-2'-deoxyuridine-labeled DNA in situ.
PloS one 2012;7(12):e52584.
2012: Radek Liboska; Anna Ligasová; Ivan Rosenberg; Dmytro Strunin; Karel Koberna
Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity.
PloS one 2012;7(12):e51679.
2011: Radek Liboska; Pavel Novák; Ondrej Páv; Radek Pohl; Dominik Rejman; Ivan Barvík; Miloš Buděšínský; Jan Snášel; Zdeněk Točík; Ivan Rosenberg
4'-Alkoxy oligodeoxynucleotides: a novel class of RNA mimics.
Organic & biomolecular chemistry 2011;9(24):8261-7.
2011: Ondrej Páv; Radek Pohl; Ivan Barvík; Miloš Buděšínský; Ivana Košiová; Ivan Rosenberg
Synthesis of oligoribonucleotides with phosphonate-modified linkages.
Organic & biomolecular chemistry 2011;9(17):6120-6.
2011: Magdalena Petrová; Miloš Buděšínský; Pavel Fiedler; Eva Zborníkovš; Ivan Rosenberg
A Ferrier-type allylic rearrangement of 3'-deoxy-3',4'-didehydronucleosides mediated by DMF dimethyl acetal: direct access to 4'-alkoxy-2',3'-didehydro-2',3'-dideoxynucleosides.
Organic letters 2011;13(16):4200-3.
2011: Sárka Králíková; Milena Masojídková; Ivan Barvík; Miloš Buděšínský; Zdeněk Točík; Ivan Rosenberg
Synthesis and properties of ApA analogues with shortened phosphonate internucleotide linkage.
Nucleosides, nucleotides & nucleic acids 2011;30(7-8):524-43.
2011: Ivana Kóšiová; Miloš Buděšínský; Natalya Panova; Ivan Rosenberg
Synthesis of novel deoxynucleoside S-methylphosphonic acids using S-(diisopropylphosphonomethyl)isothiouronium tosylate, a new equivalent of mercaptomethylphosphonate.
Organic & biomolecular chemistry 2011;9(8):2856-60.
2010: Martina Pressová; Milos Budesínský; Ivana Kosiová; Vladimír Kopecký; Josef Cvacka; Václav Kasicka; Ondrej Simák; Zdenek Tocík; Ivan Rosenberg
Oligomerization of adenosin-5'-O-ylmethylphosphonate, an isopolar AMP analogue: evaluation of the route to short oligoadenylates.
Biopolymers 2010;93(3):277-89.
2010: Petr Kocalka; Dominik Rejman; Václav Vanek; Markéta Rinnová; Ivana Tomecková; Sárka Králíková; Magdalena Petrová; Ondrej Páv; Radek Pohl; Milos Budesínský; Radek Liboska; Zdenek Tocík; Natalya Panova; Ivan Votruba; Ivan Rosenberg
Structural diversity of nucleoside phosphonic acids as a key factor in the discovery of potent inhibitors of rat T-cell lymphoma thymidine phosphorylase.
Bioorganic & medicinal chemistry letters 2010;20(3):862-5.
2009: Jan Snásel; Ivan Rosenberg; Ondrej Paces; Iva Pichová
Mapping of HIV-1 integrase preferences for target site selection with various oligonucleotides.
Archives of biochemistry and biophysics 2009;488(2):153-62.
2009: Zdenek Tocík; Milos Budesínský; Ivan Barvík; Ivan Rosenberg
Conformational evaluation of labeled C3'-O-P-(13)CH(2)-O-C4'' phosphonate internucleotide linkage, a phosphodiester isostere.
Biopolymers 2009;91(7):514-29.
2009: Václav Vanek; Milos Budesínský; Petra Kabeleová; Miloslav Sanda; Milan Kozísek; Ivona Hanclová; Jana Mládková; Jirí Brynda; Ivan Rosenberg; Markos Koutmos; Timothy A Garrow; Jirí Jirácek
Structure-activity study of new inhibitors of human betaine-homocysteine S-methyltransferase.
Journal of medicinal chemistry 2009;52(12):3652-65.
2009: Hana Vaisocherová; Jan Snásel; Tomás Springer; Hana Sípová; Ivan Rosenberg; Josef Stepánek; Jirí Homola
Surface plasmon resonance study on HIV-1 integrase strand transfer activity.
Analytical and bioanalytical chemistry 2009;393(4):1165-72.
2009: Jan Snásel; Ivan Rosenberg; Ondrej Paces; Iva Pichová
The strand transfer oligonucleotide inhibitors of HIV-integrase.
Journal of enzyme inhibition and medicinal chemistry 2009;24(1):241-6.
2009: Zuzana Vokácová; Milos Budĕsínský; Ivan Rosenberg; Bohdan Schneider; Jirí Sponer; Vladimír Sychrovský
Structure and dynamics of the ApA, ApC, CpA, and CpC RNA dinucleoside monophosphates resolved with NMR scalar spin-spin couplings.
The journal of physical chemistry. B 2009;113(4):1182-91.
2008: Natalya Panova; Ivana Kosiová; Magdalena Petrová; Václav Vanĕk; Radek Liboska; Sona Kovacková; Petr Kocalka; Sárka Králíková; Zdenek Tocík; Ondrej Páv; Ondrej Paces; Dominik Rejman; Ivan Rosenberg
Nucleoside phosphonic acids in thymidine phosphorylase inhibition: structure-activity relationship.
Nucleic acids symposium series (2004) 2008;(52):665-6.
2008: Maqdalena Petrová; Sárka Králíková; Milos Budesínský; Ivan Rosenberg
From ribonucleoside 5'-aldehydes to ribonucleoside 5'-C-phosphonates as building blocks for oligonucleotide synthesis.
Nucleic acids symposium series (2004) 2008;(52):591-2.
2008: Sona Kovacková; Ondrej Paces; Martin Dracínský; Ivan Rosenberg; Dominik Rejman
Piperidine nucleosides and nucleotides.
Nucleic acids symposium series (2004) 2008;(52):587.
2008: Dominik Rejman; Radek Pohl; Sona Kovacková; Petr Kocalka; Alzbĕta Svenková; Hana Sanderová; Libor Krásný; Ivan Rosenberg
Pyrrolidine analogues of nucleosides and nucleotides.
Nucleic acids symposium series (2004) 2008;(52):577-8.
2008: Ivana Kósíová; Ivan Rosenberg
Synthesis of nucleoside 5'-S-methylphosphonates and related compounds.
Nucleic acids symposium series (2004) 2008;(52):569-70.
2008: Václav Vanĕk; Milos Budĕsínský; Radek Liboska; Vladimíra Hurychová; Ivan Rosenberg
Prolinol-based nucleoside phosphonic acids: synthesis and properties.
Nucleic acids symposium series (2004) 2008;(52):537-8.
2008: Zdenek Tocík; Milos Budĕsínský; Ivan Barvík; Ivan Rosenberg
On the stereochemistry of C3'-O-P-CH2-O-C4'' phosphonate internucleotide bond, a phosphate isostere.
Nucleic acids symposium series (2004) 2008;(52):427-8.
2008: Radek Liboska; Magdalena Petrová; Radek Pohl; Milos Budesínsky; Vladimíra Hurychová; Ivan Rosenberg
Chiral phosphonate internucleotide linkage: a promising modification for chimeric oligonucleotides?
Nucleic acids symposium series (2004) 2008;(52):317-8.
2007: Ondrej Páv; Ivan Barvík; Milos Budesínský; Milena Masojídková; Ivan Rosenberg
Ring enlargement of cyclic acetals and ketals: a way to seven-membered nucleoside phostones.
Organic letters 2007;9(26):5469-72.
2006: Zdenek Tocík; Ivan Barvík; Milos Budesínský; Ivan Rosenberg
Novel isosteric, isopolar phosphonate analogs of oligonucleotides: preparation and properties.
Biopolymers 2006;83(4):400-13.
2006: Hana Vaisocherová; Alice Zítová; Markéta Lachmanová; Josef Stepánek; Sárka Králíková; Radek Liboska; Dominik Rejman; Ivan Rosenberg; Jirí Homola
Investigating oligonucleotide hybridization at subnanomolar level by surface plasmon resonance biosensor method.
Biopolymers 2006;82(4):394-8.
2006: Jiri Jiracek; Michaela Collinsova; Ivan Rosenberg; Milos Budesinsky; Eva Protivinska; Hana Netusilova; Timothy A Garrow
S-alkylated homocysteine derivatives: new inhibitors of human betaine-homocysteine S-methyltransferase.
Journal of medicinal chemistry 2006;49(13):3982-9.
2006: Ondrej Pav; Eva Protivinska; Martina Pressova; Michaela Collinsova; Jiri Jiracek; Jan Snasel; Milena Masojidkova; Milos Budesinsky; Ivan Rosenberg
Activation of murine RNase L by isopolar 2'-phosphonate analogues of 2',5' oligoadenylates.
Journal of medicinal chemistry 2006;49(13):3955-62.
2005: Petr Kocalka; Radek Pohl; Dominik Rejman; Ivan Rosenberg
Synthesis of racemic and enantiomeric 3-pyrrolidinyl derivatives of purine and pyrimidine nucleobases.
Nucleosides, nucleotides & nucleic acids 2005;24(5-7):805-8.
2005: Jan Snásel; Zdenek Krejcík; Vera Jencová; Ivan Rosenberg; Tomás Ruml; Jerry Alexandratos; Alla Gustchina; Iva Pichová
Integrase of Mason-Pfizer monkey virus.
The FEBS journal 2005;272(1):203-16.
2004: Daniel Nemecek; Josef Stepanek; Pierre-Yves Turpin; Ivan Rosenberg
Raman study of potential "antisense" drugs: nonamer oligonucleotide duplexes with a central mismatch as a model system for the binding selectivity evaluation.
Biopolymers 2004;74(1-2):115-9.
2004: Eva Kocisová; Petr Praus; Ivan Rosenberg; Olivier Seksek; Franck Sureau; Josef Stĕpánek; Pierre-Yves Turpin
Intracellular uptake of modified oligonucleotide studied by two fluorescence techniques.
Biopolymers 2004;74(1-2):110-4.
2004: Dominik Rejman; Milena Masojídková; Ivan Rosenberg
Nucleosidyl-O-Methylphosphonates: a pool of monomers for modified oligonucleotides.
Nucleosides, nucleotides & nucleic acids 2004;23(11):1683-705.
2004: Gabriel Birkus; Dominik Rejman; Miroslav Otmar; Ivan Votruba; Ivan Rosenberg; Antonin Holy
The substrate activity of (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine diphosphate toward DNA polymerases alpha, delta and epsilon.
Antiviral chemistry & chemotherapy 2004;15(1):23-33.
2003: Václav Vanek; Milos Budesínský; Ivana Kavenová; Markéta Rinnová; Ivan Rosenberg
Isosteric phosphonate pyrrolidine-based dinucleoside monophosphate analogues.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1065-7.
2003: Sárka Králíková; Milos Budesínský; Ivan Rosenberg
A-hydroxyphosphonate oligonucleotides: a promising DNA type?
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1061-4.
2003: Radek Liboska; Milos Budesínský; Ivana Dvoráková-Kavenová; Ondrej Páv; Ivan Rosenberg
Hybridization properties of 4'-branched oligonucleotides.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1057-60.
2003: Ondrej Páv; Milos Budesínský; Ivan Rosenberg
Ribo-, xylo-, and arabino-configured adenine-based nucleoside phosphonates: synthesis of monomers for solid-phase oligonucleotide assembly.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1053-6.
2003: Martina Pressová; Radek Liboska; Milos Budesínský; Sárka Králíková; Ivana Kavenová; Ivan Rosenberg
Oligomerization aiming at phosphonate analogues of oligoadenylates.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1049-52.
2003: Sárka Králíková; Milena Masojídková; Milos Budĕsínský; Ivan Rosenberg
Study on reactivity and protection of the alpha-hydroxyphosphonate moiety in 5'-nucleotide analogues: formation of the 3'-O-P-C(OH)-C4' internucleotide linkage.
Nucleosides, nucleotides & nucleic acids 2003;22(3):329-47.
2002: Petr Praus; Dana Gaskova; Eva Kocisova; Roman Chaloupka; Josef Stepanek; Jirí Bok; Dominik Rejman; Ivan Rosenberg; Pierre-Yves Turpin; Franck Sureau
Spectral decomposition of intracellular complex fluorescence using multiple-wavelength phase modulation lifetime determination: technical approach and preliminary applications.
Biopolymers 2002;67(4-5):339-43.
2001: Jan Hanus; Ivan Barvík; K Ruszová-Chmelová; Josef Stepánek; Pierre-Yves Turpin; Jirí Bok; Ivan Rosenberg; M Petrová-Endová
-CH2- lengthening of the internucleotide linkage in the ApA dimer can improve its conformational compatibility with its natural polynucleotide counterpart.
Nucleic acids research 2001;29(24):5182-94.
2001: Dominik Rejman; Milena Masojídková; Erik De Clercq; Ivan Rosenberg
2'C-alkoxy and 2'-C-aryloxy derivatives of N-(2-phosphonomethoxyethyl)-purines and -pyrimidines: synthesis and biological activity.
Nucleosides, nucleotides & nucleic acids 2001;20(8):1497-522.
2001: Dominik Rejman; Jan Snásel; Radek Liboska; Zdenek Tocík; O Paces; Sárka Králíková; Markéta Rinnová; P Kois; Ivan Rosenberg
Oligonucleotides with isopolar phosphonate internucleotide linkage: a new perspective for antisense compounds?
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):819-23.
2001: Jan Snásel; Dominik Rejman; Radek Liboska; Zdenek Tocík; Tomás Ruml; Ivan Rosenberg; Iva Pichová
Inhibition of HIV-1 integrase by modified oligonucleotides derived from U5' LTR.
European journal of biochemistry / FEBS 2001;268(4):980-6.
2000: Sárka Králíková; M Budĕsínský; M Masojidková; Ivan Rosenberg
Efficient synthesis of 2'-deoxynucleoside 3'-C-phosphonates: reactivity of geminal hydroxyphosphonate moiety.
Nucleosides, nucleotides & nucleic acids 2000;19(7):1159-83.
1998: M Pressová; M Endová; Z Toĉík; Radek Liboska; Ivan Rosenberg
UV spectroscopy study on complexes of phosphonate ApA analogs with poly(U): promising step in prediction of oligonucleotide analog properties?
Bioorganic & medicinal chemistry letters 1998;8(10):1225-30.