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Joseph Rosenblatt

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Yu Zhang; Yair Eliav; Eckhard R Podack; Taylor H Schreiber; Seung-Uon Shin; Tamar Tadmor; Joseph D Rosenblatt
B lymphocyte inhibition of anti-tumor response depends on expansion of Treg but is independent of B-cell IL-10 secretion.
Barbara Pro; Rod Ramchandren; Joseph D Rosenblatt; Eric L Sievers; Yin Yang; Ranjana Advani; Nancy L Bartlett; Pauline Brice; Joseph Michael Connors; Michelle Fanale; Tim Illidge; Dana A Kennedy; Jeffrey Matous; Andrei Shustov
Brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large-cell lymphoma: results of a phase II study.
Anas Younes; Stephen M Ansell; Nancy L Bartlett; Bruce D Cheson; Joseph Michael Connors; Sven de Vos; Andreas Engert; Andres Forero-Torres; Ajay K Gopal; Dana A Kennedy; Emily K Larsen; Craig H Moskowitz; Rod Ramchandren; Joseph D Rosenblatt; Kerry J Savage; Eric L Sievers; Scott E Smith; Robert Chen
Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkin's lymphoma.

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All Publications

2013: Yu Zhang; Yair Eliav; Eckhard R Podack; Taylor H Schreiber; Seung-Uon Shin; Tamar Tadmor; Joseph D Rosenblatt
B lymphocyte inhibition of anti-tumor response depends on expansion of Treg but is independent of B-cell IL-10 secretion.
Cancer immunology, immunotherapy : CII 2013;62(1):87-99.
2012: Barbara Pro; Rod Ramchandren; Joseph D Rosenblatt; Eric L Sievers; Yin Yang; Ranjana Advani; Nancy L Bartlett; Pauline Brice; Joseph Michael Connors; Michelle Fanale; Tim Illidge; Dana A Kennedy; Jeffrey Matous; Andrei Shustov
Brentuximab vedotin (SGN-35) in patients with relapsed or refractory systemic anaplastic large-cell lymphoma: results of a phase II study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(18):2190-6.
2012: Anas Younes; Stephen M Ansell; Nancy L Bartlett; Bruce D Cheson; Joseph Michael Connors; Sven de Vos; Andreas Engert; Andres Forero-Torres; Ajay K Gopal; Dana A Kennedy; Emily K Larsen; Craig H Moskowitz; Rod Ramchandren; Joseph D Rosenblatt; Kerry J Savage; Eric L Sievers; Scott E Smith; Robert Chen
Results of a pivotal phase II study of brentuximab vedotin for patients with relapsed or refractory Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(18):2183-9.
2012: Andres Forero-Torres; Dana A Kennedy; Joseph D Rosenblatt; Ranjana Advani; Nancy L Bartlett; Michelle A Fanale; Anas Younes
Brentuximab vedotin in transplant-naive patients with relapsed or refractory hodgkin lymphoma: analysis of two phase I studies.
The oncologist 2012;17(8):1073-80.
2012: Michelle A Fanale; Andres Forero-Torres; Anna R Franklin; Tae H Han; Dana A Kennedy; Joseph D Rosenblatt; Eric L Sievers; Ranjana H Advani; Nancy L Bartlett
A phase I weekly dosing study of brentuximab vedotin in patients with relapsed/refractory CD30-positive hematologic malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(1):248-55.
2011: Yehuda E Deutsch; Eckhard R Podack; Tamar Tadmor; Joseph D Rosenblatt
CD30: an important new target in hematologic malignancies.
Leukemia & lymphoma 2011;52(9):1641-54.
2011: Margaret M Byrne; Jill L Halman; Leonidas G Koniaris; Peter A Cassileth; Joseph D Rosenblatt; Michael C Cheung
Effects of poverty and race on outcomes in acute myeloid leukemia.
American journal of clinical oncology 2011;34(3):297-304.
2011: Tamar Tadmor; Yu Zhang; Hyun-Mi Cho; Eckhard R Podack; Joseph D Rosenblatt
The absence of B lymphocytes reduces the number and function of T-regulatory cells and enhances the anti-tumor response in a murine tumor model.
Cancer immunology, immunotherapy : CII 2011;60(5):609-19.
2011: Seung-Uon Shin; Hyun-Mi Cho; Jaime Merchan; Jin Zhang; Krisztina Kovacs; Yawu Jing; Sundaram Ramakrishnan; Joseph D Rosenblatt
Targeted delivery of an antibody-mutant human endostatin fusion protein results in enhanced antitumor efficacy.
Molecular cancer therapeutics 2011;10(4):603-14.
2011: Sehyo C Choe; Hyun-Mi Cho; Joseph D Rosenblatt; Seung-Uon Shin; Guannan Zhao; Zhenyuan Zhao; Neil F Johnson
Model for in vivo progression of tumors based on co-evolving cell population and vasculature.
Scientific reports 2011;1():31.
2010: Hyun-Mi Cho; Joseph D Rosenblatt; Khaled A Tolba; Sarah J Shin; Daniel S Shin; Carmen Calfa; Yu Zhang; Seung-Uon Shin
Delivery of NKG2D ligand using an anti-HER2 antibody-NKG2D ligand fusion protein results in an enhanced innate and adaptive antitumor response.
Cancer research 2010;70(24):10121-30.
2010: Taylor Schreiber; Luis E Raez; Joseph D Rosenblatt; Eckhard R Podack
Tumor immunogenicity and responsiveness to cancer vaccine therapy: the state of the art.
Seminars in immunology 2010;22(3):105-12.
2010: Karen Moffitt; Frank Brogan; Clarence Brown; Michael Kasper; Joseph D Rosenblatt; Robert Smallridge; Daniel Sullivan; Jeffrey Kromrey
Statewide cancer clinical trial navigation service.
Journal of oncology practice / American Society of Clinical Oncology 2010;6(3):127-32.
2010: Izidore S Lossos; Peter Joel Hosein; Daniel Morgensztern; Francine Coleman; Maricer Escalon; Gerald E Byrne; Joseph D Rosenblatt; Gail R. Walker
High rate and prolonged duration of complete remissions induced by rituximab, methotrexate, doxorubicin, cyclophosphamide, vincristine, ifosfamide, etoposide, cytarabine, and thalidomide (R-MACLO-IVAM-T), a modification of the National Cancer Institute 89-C-41 regimen, in patients with newly diagnosed mantle cell lymphoma.
Leukemia & lymphoma 2010;51(3):406-14.
2009: Kristopher A Sarosiek; hovav nechushtan; Xiaoqing Lu; Joseph D Rosenblatt; Izidore S Lossos
Interleukin-4 distinctively modifies responses of germinal centre-like and activated B-cell-like diffuse large B-cell lymphomas to immuno-chemotherapy.
British journal of haematology 2009;147(3):308-18.
2009: Ranjana Advani; Andres Forero-Torres; Richard R Furman; Joseph D Rosenblatt; Anas Younes; Hong Ren; Kate Harrop; Nancy Whiting; Jonathan G Drachman
Phase I study of the humanized anti-CD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(26):4371-7.
2009: Andres Forero-Torres; John P Leonard; Anas Younes; Joseph D Rosenblatt; Pauline Brice; Nancy L Bartlett; Andre Bosly; Lauren Pinter-Brown; Dana Kennedy; Eric L Sievers; Ajay K Gopal
A Phase II study of SGN-30 (anti-CD30 mAb) in Hodgkin lymphoma or systemic anaplastic large cell lymphoma.
British journal of haematology 2009;146(2):171-9.
2009: Taylor Schreiber; Vadim Deyev; Joseph D Rosenblatt; Eckhard R Podack
Tumor-induced suppression of CTL expansion and subjugation by gp96-Ig vaccination.
Cancer research 2009;69(5):2026-33.
2008: Satoshi Oizumi; Vadim Deyev; Koichi Yamazaki; Taylor Schreiber; Natasa Strbo; Joseph D Rosenblatt; Eckhard R Podack
Surmounting tumor-induced immune suppression by frequent vaccination or immunization in the absence of B cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(4):394-401.
2008: hovav nechushtan; Dien Pham; Yu Zhang; Daniel Morgensztern; Kyung H Yi; Seung-Uon Shin; Howard Federoff; William J Bowers; Khaled A Tolba; Joseph D Rosenblatt
Augmentation of anti-tumor responses of adoptively transferred CD8+T cells in the lymphopenic setting by HSV amplicon transduction.
Cancer immunology, immunotherapy : CII 2008;57(5):663-75.
2008: Nancy L Bartlett; Anas Younes; Matthew H Carabasi; Andres Forero; Joseph D Rosenblatt; John P Leonard; Steven H Bernstein; R Gregory Bociek; Jennie M Lorenz; Bruce W Hart; Jeremy Barton
A phase 1 multidose study of SGN-30 immunotherapy in patients with refractory or recurrent CD30+ hematologic malignancies.
Blood 2008;111(4):1848-54.
2007: Kyung H Yi; hovav nechushtan; William J Bowers; Gail R. Walker; Yu Zhang; Dien G Pham; Eckhard R Podack; Howard Federoff; Khaled A Tolba; Joseph D Rosenblatt
Adoptively transferred tumor-specific T cells stimulated ex vivo using herpes simplex virus amplicons encoding 4-1BBL persist in the host and show antitumor activity in vivo.
Cancer research 2007;67(20):10027-37.
2007: Izidore S Lossos; Daniel Morgensztern; Marcelo Blaya; Alvaro Alencar; Denise Pereira; Joseph D Rosenblatt
Rituximab for treatment of chemoimmunotherapy naive marginal zone lymphoma.
Leukemia & lymphoma 2007;48(8):1630-2.
2007: Joseph D Rosenblatt; Yu Zhang; Tamar Tadmor
Inhibition of antitumor immunity by B cells.
Cancer research 2007;67(10):5058-9; author reply 5059.
2006: Luis E Raez; Joseph D Rosenblatt; Eckhard R Podack
Present and future of lung cancer vaccines.
Expert opinion on emerging drugs 2006;11(3):445-59.
2005: Valentine B Andela; Edward M Schwarz; Regis J O'Keefe; Edward J Puzas; Joseph D Rosenblatt; Randy N Rosier
A genome-wide expression profile and system-level integration of nuclear factor kappa B regulated genes reveals fundamental metabolic adaptations during cell growth and survival.
FEBS letters 2005;579(30):6814-20.
2005: Sangeeta Shah; Anagha A Divekar; Shannon P Hilchey; Hyun-Mi Cho; Corliss L Newman; Seung-Uon Shin; hovav nechushtan; Pia M Challita-Eid; Benjamin M Segal; Kyung Hee Yi; Joseph D Rosenblatt
Increased rejection of primary tumors in mice lacking B cells: inhibition of anti-tumor CTL and TH1 cytokine responses by B cells.
International journal of cancer. Journal international du cancer 2005;117(4):574-86.
2005: Gustavo A Heresi; Jingcheng Wang; Russell Taichman; Julio A Chirinos; Jacinto J Regalado; Daniel M Lichtstein; Joseph D Rosenblatt
Expression of the chemokine receptor CCR7 in prostate cancer presenting with generalized lymphadenopathy: report of a case, review of the literature, and analysis of chemokine receptor expression.
Urologic oncology 2005;23(4):261-7.
2005: Hyun-Mi Cho; Joseph D Rosenblatt; Young-Sook Kang; M Luisa Iruela-Arispe; Sherie L Morrison; Manuel L Penichet; Young-Guen Kwon; Tae-Woong Kim; Keith A Webster; hovav nechushtan; Seung-Uon Shin
Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein.
Molecular cancer therapeutics 2005;4(6):956-67.
2004: Daniel Morgensztern; Manuel F Rosado; Orlando Silva; Edgardo S Santos; Sakher Abdullah; Mark Goodman; Kara Hamilton-Nelson; Joseph D Rosenblatt; Izidore S Lossos
Prevalence of hepatitis C infection in patients with non-Hodgkin's lymphoma in South Florida and review of the literature.
Leukemia & lymphoma 2004;45(12):2459-64.
2004: Edgardo S Santos; Joseph D Rosenblatt; Mark Goodman
Role of farnesyltransferase inhibitors in hematologic malignancies.
Expert review of anticancer therapy 2004;4(5):843-56.
2004: R John Looney; Jennifer H Anolik; Debbie Campbell; Raymond E Felgar; Faith Young; Lois J Arend; James A Sloand; Joseph D Rosenblatt; Iñaki Sanz
B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab.
Arthritis and rheumatism 2004;50(8):2580-9.
2004: Rafael G Amado; Ronald T Mitsuyasu; Joseph D Rosenblatt; Frances K Ngok; Andreas Bakker; Steve Cole; Nathalie Chorn; Lii-Shin Lin; Gregory Bristol; Maureen P Boyd; Janet Macpherson; Gregory C Fanning; Alison V Todd; Julie A Ely; Jerome A Zack; Geoff Symonds
Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients.
Human gene therapy 2004;15(3):251-62.
2004: Harindra R Abeysinghe; Stephen J Pollock; Nedra L Guckert; Yana Veyberman; Peter C Keng; Marc Halterman; Howard Federoff; Joseph D Rosenblatt; Nancy Wang
The role of the THY1 gene in human ovarian cancer suppression based on transfection studies.
Cancer genetics and cytogenetics 2004;149(1):1-10.
2004: Kishan J Pandya; Anuradha R Thummala; Jennifer J Griggs; Joseph D Rosenblatt; Deepak M Sahasrabudhe; Thomas Guttuso; Gary R Morrow; Joseph A Roscoe
Pilot study using gabapentin for tamoxifen-induced hot flashes in women with breast cancer.
Breast cancer research and treatment 2004;83(1):87-9.
2003: Valentine B Andela; Michael Pirri; Edward M Schwarz; Edward J Puzas; Regis J O'Keefe; Joseph D Rosenblatt; Randy N Rosier
The mevalonate synthesis pathway as a therapeutic target in cancer.
Clinical orthopaedics and related research 2003;(415 Suppl):S59-66.
2003: Jane L Liesveld; Jeffrey E Lancet; Karen Rosell; A Menon; Chaohui Lu; C McNair; Camille N Abboud; Joseph D Rosenblatt
Effects of the farnesyl transferase inhibitor R115777 on normal and leukemic hematopoiesis.
Leukemia 2003;17(9):1806-12.
2003: Joseph D Rosenblatt; William J Harrington
Leukemia and myelopathy: the persistent mystery of pathogenesis by HTLV-I/II.
Cancer investigation 2003;21(2):323-4.
2003: Alok A Khorana; Joseph D Rosenblatt; Deepak M Sahasrabudhe; T Evans; M Ladrigan; D Marquis; Karen Rosell; T Whiteside; S Phillippe; Bruce Acres; Philippe Slos; Patrick Squiban; M Ross; K Kendra
A phase I trial of immunotherapy with intratumoral adenovirus-interferon-gamma (TG1041) in patients with malignant melanoma.
Cancer gene therapy 2003;10(4):251-9.
2003: Jennifer H Anolik; Debbie Campbell; Raymond E Felgar; Faith Young; Iñaki Sanz; Joseph D Rosenblatt; R John Looney
The relationship of FcgammaRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus.
Arthritis and rheumatism 2003;48(2):455-9.
2002: Khaled A Tolba; William J Bowers; Jacquelyn Muller; Vickie Housekneckt; Rita E Giuliano; Howard Federoff; Joseph D Rosenblatt
Herpes simplex virus (HSV) amplicon-mediated codelivery of secondary lymphoid tissue chemokine and CD40L results in augmented antitumor activity.
Cancer research 2002;62(22):6545-51.
2002: Joseph D Rosenblatt; Seung-Uon Shin; hovav nechushtan; Kyung Hee Yi; Khaled A Tolba
Potential role of chemokines in immune therapy of cancer.
The Israel Medical Association journal : IMAJ 2002;4(11):1054-9.
2002: Khaled A Tolba; William J Bowers; David J Eling; Ann E Casey; Thomas Kipps; Howard Federoff; Joseph D Rosenblatt
HSV amplicon-mediated delivery of LIGHT enhances the antigen-presenting capacity of chronic lymphocytic leukemia.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(4):455-63.
2002: Jeffrey E Lancet; Joseph D Rosenblatt; Judith E Karp
Farnesyltransferase inhibitors and myeloid malignancies: phase I evidence of Zarnestra activity in high-risk leukemias.
Seminars in hematology 2002;39(3 Suppl 2):31-5.
2002: Valentine B Andela; Joseph D Rosenblatt; Edward M Schwarz; Edward J Puzas; Regis J O'Keefe; Randy N Rosier
Synergism of aminobisphosphonates and farnesyl transferase inhibitors on tumor metastasis.
Clinical orthopaedics and related research 2002;(397):228-39.
2001: William D Foulkes; Joseph D Rosenblatt; Pierre O Chappuis
The contribution of inherited factors to the clinicopathological features and behavior of breast cancer.
Journal of mammary gland biology and neoplasia 2001;6(4):453-65.
2001: Yuhchyau Chen; Kishan J Pandya; P P Keng; Richard Feins; R Raubertas; Therese Smudzin; Joseph D Rosenblatt; Paul Okunieff
Schedule-dependent pulsed paclitaxel radiosensitization for thoracic malignancy.
American journal of clinical oncology 2001;24(5):432-7.
2001: Matthew J Renda; Joseph D Rosenblatt; E Klimatcheva; Lisa M Demeter; Robert A Bambara; Vicente Planelles
Mutation of the methylated tRNA(Lys)(3) residue A58 disrupts reverse transcription and inhibits replication of human immunodeficiency virus type 1.
Journal of virology 2001;75(20):9671-8.
2001: R T Belly; Joseph D Rosenblatt; M Steinmann; J Toner; J Sun; J Shehadi; J L Peacock; R F Raubertas; N Jani; Charlotte K Ryan
Detection of mutated K12-ras in histologically negative lymph nodes as an indicator of poor prognosis in stage II colorectal cancer.
Clinical colorectal cancer 2001;1(2):110-6.
2001: Khaled A Tolba; William J Bowers; Shannon P Hilchey; Marc W Halterman; Darlene F Howard; Rita E Giuliano; Howard Federoff; Joseph D Rosenblatt
Development of herpes simplex virus-1 amplicon-based immunotherapy for chronic lymphocytic leukemia.
Blood 2001;98(2):287-95.
2001: E Klimatcheva; Vicente Planelles; S L Day; F Fulreader; Matthew J Renda; Joseph D Rosenblatt
Defective lentiviral vectors are efficiently trafficked by HIV-1 and inhibit its replication.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(6):928-39.
2001: Judith E Karp; Jeffrey E Lancet; Scott H Kaufmann; David W End; John J Wright; K Bol; I Horak; Michael L Tidwell; Jane L Liesveld; Timothy J Kottke; D Ange; Laxmi N Buddharaju; Ivana Gojo; W Edward Highsmith; Robert T Belly; R J Hohl; M E Rybak; A Thibault; Joseph D Rosenblatt
Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial.
Blood 2001;97(11):3361-9.
2001: Manuel L Penichet; Jay S Dela Cruz; Pia M Challita-Eid; Joseph D Rosenblatt; Sherie L Morrison
A murine B cell lymphoma expressing human HER2 / neu undergoes spontaneous tumor regression and elicits antitumor immunity.
Cancer immunology, immunotherapy : CII 2001;49(12):649-62.
2001: Alok A Khorana; Joseph D Rosenblatt; F M Young
Immunopathogenesis of HIV and HTLV-1 infection: mechanisms for lymphomagenesis.
Cancer treatment and research 2001;104():19-74.
2000: J J Ifthikharuddin; L A Mieles; Joseph D Rosenblatt; Charlotte K Ryan; Deepak M Sahasrabudhe
CD-20 expression in post-transplant lymphoproliferative disorders: treatment with rituximab.
American journal of hematology 2000;65(2):171-3.
2000: STEVEN ROSENBERG; R. Michael Blaese; M K Brenner; A B Deisseroth; F D Ledley; M T Lotze; J M Wilson; Gary Nabel; K Cornetta; J S Economou; S M Freeman; S R Riddell; M Brenner; E Oldfield; B Gansbacher; C Dunbar; Robert E Walker; F G Schuening; J A Roth; R G Crystal; M J Welsh; K Culver; H E Heslop; J Simons; R W Wilmott; R C Boucher; H F Siegler; J A Barranger; S Karlsson; D Kohn; J E Galpin; C Raffel; Charles Hesdorffer; J Ilan; Peter A Cassileth; J O'Shaughnessy; L E Kun; T K Das; F Wong-Staal; R E Sobol; R Haubrich; M Sznol; J Rubin; E J Sorcher; Joseph D Rosenblatt; R Walker; K Brigham; N Vogelzang; E Hersh; S L Eck
Human gene marker/therapy clinical protocols.
Human gene therapy 2000;11(6):919-79.
2000: Roxana Moslehi; W Chu; Beth Y Karlan; David Fishman; Harvey A Risch; A Fields; David Smotkin; Yaacov Ben David; Joseph D Rosenblatt; D Russo; P Schwartz; Nadine Tung; Ellen Warner; Barry Rosen; J Friedman; Jean-Sebastien Brunet; Steven A Narod
BRCA1 and BRCA2 mutation analysis of 208 Ashkenazi Jewish women with ovarian cancer.
American journal of human genetics 2000;66(4):1259-72.
1999: Pierre O Chappuis; Joseph D Rosenblatt; William D Foulkes
The influence of familial and hereditary factors on the prognosis of breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(10):1163-70.
1999: Rafael G Amado; Ronald T Mitsuyasu; Geoff Symonds; Joseph D Rosenblatt; J Zack; Lun-Quan Sun; M Miller; Julie A Ely; Wayne Gerlach
A phase I trial of autologous CD34+ hematopoietic progenitor cells transduced with an anti-HIV ribozyme.
Human gene therapy 1999;10(13):2255-70.
1999: L D Shostak; J Ludlow; J Fisk; S Pursell; BJ Rimel; D Nguyen; Joseph D Rosenblatt; Vicente Planelles
Roles of p53 and caspases in the induction of cell cycle arrest and apoptosis by HIV-1 vpr.
Experimental cell research 1999;251(1):156-65.
1999: E Klimatcheva; Joseph D Rosenblatt; Vicente Planelles
Lentiviral vectors and gene therapy.
Frontiers in bioscience : a journal and virtual library 1999;4():D481-96.
1999: Manuel L Penichet; P M Challita; Seung-Uon Shin; Sharon Sampogna; Joseph D Rosenblatt; Sherie L Morrison
In vivo properties of three human HER2/neu-expressing murine cell lines in immunocompetent mice.
Laboratory animal science 1999;49(2):179-88.
1999: S M White; Matthew J Renda; N Y Nam; E Klimatcheva; Y Zhu; J Fisk; Marc W Halterman; BJ Rimel; Howard Federoff; Shree Pandya; Joseph D Rosenblatt; Vicente Planelles
Lentivirus vectors using human and simian immunodeficiency virus elements.
Journal of virology 1999;73(4):2832-40.
1999: M Kutubuddin; Howard Federoff; Pia M Challita-Eid; Marc W Halterman; B Day; Mark Atkinson; Vicente Planelles; Joseph D Rosenblatt
Eradication of pre-established lymphoma using herpes simplex virus amplicon vectors.
Blood 1999;93(2):643-54.
1998: Pia M Challita-Eid; E Klimatcheva; B T Day; T Evans; K Dreyer; BJ Rimel; Joseph D Rosenblatt; Vicente Planelles
Inhibition of HIV type 1 infection with a RANTES-IgG3 fusion protein.
AIDS research and human retroviruses 1998;14(18):1617-24.
1998: Pia M Challita-Eid; Camille N Abboud; Sherie L Morrison; Manuel L Penichet; Karen Rosell; T Poles; Shannon P Hilchey; Vicente Planelles; Joseph D Rosenblatt
A RANTES-antibody fusion protein retains antigen specificity and chemokine function.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3729-36.
1998: Pia M Challita-Eid; Manuel L Penichet; Seung-Uon Shin; T Poles; N Mosammaparast; K Mahmood; Dennis J Slamon; Sherie L Morrison; Joseph D Rosenblatt
A B7.1-antibody fusion protein retains antibody specificity and ability to activate via the T cell costimulatory pathway.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3419-26.
1998: Robert C Seeger; Joseph D Rosenblatt; R E Duerst; Charles Patrick Reynolds; Judith G Villablanca; B Hasenauer; S A Feig
A Phase I study of human gamma interferon gene-transduced tumor cells in patients with neuroblastoma.
Human gene therapy 1998;9(3):379-90.
1998: Rafael G Amado; Geoff Symonds; Beth D Jamieson; G Zhao; Joseph D Rosenblatt; Jerome A Zack
Effects of megakaryocyte growth and development factor on survival and retroviral transduction of T lymphoid progenitor cells.
Human gene therapy 1998;9(2):173-83.
1997: Graham R Bignell; Federico Canzian; M Shayeghi; M Stark; Yin Yao Shugart; PJ Biggs; J Mangion; Rifat A Hamoudi; Joseph D Rosenblatt; P Buu; S Sun; S S Stoffer; David E Goldgar; Giovanni Romeo; richard Houlston; Steven A Narod; Michael R Stratton; WD Foulkes
Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer.
American journal of human genetics 1997;61(5):1123-30.
1997: Y Lu; Vicente Planelles; X Li; Chockalingam Palaniappan; B Day; Pia M Challita-Eid; Rafael G Amado; D Stephens; D B Kohn; A Bakker; Philip J Fay; Robert A Bambara; Joseph D Rosenblatt
Inhibition of HIV-1 replication using a mutated tRNALys-3 primer.
The Journal of biological chemistry 1997;272(23):14523-31.
1997: O C Ferreira; Vicente Planelles; Joseph D Rosenblatt
Human T-cell leukemia viruses: epidemiology, biology, and pathogenesis.
Blood reviews 1997;11(2):91-104.
1996: A Bakker; X Li; C T Ruland; D W Stephens; A C Black; Joseph D Rosenblatt
Human T-cell leukemia virus type 2 Rex inhibits pre-mRNA splicing in vitro at an early stage of spliceosome formation.
Journal of virology 1996;70(8):5511-8.
1996: C T Watanabe; Joseph D Rosenblatt; A Bakker; J P Morgan; J Luo; S Chun; A C Black
Negative regulation of gene expression from the HTLV type II long terminal repeat by Rex: functional and structural dissociation from positive posttranscriptional regulation.
AIDS research and human retroviruses 1996;12(6):535-46.
1996: A C Black; J Luo; S Chun; A Bakker; John K Fraser; Joseph D Rosenblatt
Specific binding of polypyrimidine tract binding protein and hnRNP A1 to HIV-1 CRS elements.
Virus genes 1996;12(3):275-85.
1995: A C Black; J Luo; C Watanabe; S Chun; A Bakker; John K Fraser; J P Morgan; Joseph D Rosenblatt
Polypyrimidine tract-binding protein and heterogeneous nuclear ribonucleoprotein A1 bind to human T-cell leukemia virus type 2 RNA regulatory elements.
Journal of virology 1995;69(11):6852-8.
1995: K A Woodruff; Joseph D Rosenblatt; Theodore B Moore; R H Medzoyan; D S Pai; J L Noland; Joyce Yamashiro; R K Wada
Cell type-specific activity of the N-myc promoter in human neuroblastoma cells is mediated by a downstream silencer.
Oncogene 1995;10(7):1335-41.
1995: Joseph D Rosenblatt; S Miles; Judith C Gasson; D Prager
Transactivation of cellular genes by human retroviruses.
Current topics in microbiology and immunology 1995;193():25-49.
1995: E Ejima; Joseph D Rosenblatt; J Ou; D Prager
Parathyroid hormone-related protein gene expression and human T cell leukemia virus-1 infection.
Mineral and electrolyte metabolism 1995;21(1-3):143-7.
1994: Y Kilim; Joseph D Rosenblatt; Y L Danon
Sequence analysis of the new human T cell leukemia/lymphoma virus type I isolate (HTLV-I) in Israel.
Israel journal of medical sciences 1994;30(12):891-4.
1994: R K Akkina; Joseph D Rosenblatt; A G Campbell; Irvin S Y Chen; Jerome A Zack
Modeling human lymphoid precursor cell gene therapy in the SCID-hu mouse.
Blood 1994;84(5):1393-8.
1994: D Prager; Joseph D Rosenblatt; E Ejima
Hypercalcemia, parathyroid hormone-related protein expression and human T-cell leukemia virus infection.
Leukemia & lymphoma 1994;14(5-6):395-400.
1994: Y L Danon; Y Kilim; Joseph D Rosenblatt
Molecular characterization of HTLV-I infection in Israel.
Annals of the New York Academy of Sciences 1994;724():417-21.
1994: Ramila Philip; E Brunette; L Kilinski; D Murugesh; M A McNally; K Ucar; Joseph D Rosenblatt; T B Okarma; Jane Lebkowski
Efficient and sustained gene expression in primary T lymphocytes and primary and cultured tumor cells mediated by adeno-associated virus plasmid DNA complexed to cationic liposomes.
Molecular and cellular biology 1994;14(4):2411-8.
1994: A C Black; C T Ruland; J Luo; A Bakker; John K Fraser; Joseph D Rosenblatt
Binding of nuclear proteins to HTLV-II cis-acting repressive sequence (CRS) RNA correlates with CRS function.
Virology 1994;200(1):29-41.
1993: Alan Saven; M L Figueroa; Lawrence D Piro; Joseph D Rosenblatt
2-Chlorodeoxyadenosine to treat refractory histiocytosis X.
The New England journal of medicine 1993;329(10):734-5.
1993: G Feuer; Jerome A Zack; William J Harrington; R Valderama; Joseph D Rosenblatt; W Wachsman; S M Baird; Irvin S Y Chen
Establishment of human T-cell leukemia virus type I T-cell lymphomas in severe combined immunodeficient mice.
Blood 1993;82(3):722-31.
1993: Joseph D Rosenblatt
Human T-lymphotropic virus types I and II.
The Western journal of medicine 1993;158(4):379-84.
1993: E Ejima; Joseph D Rosenblatt; M Massari; E Quan; D Stephens; C A Rosen; D Prager
Cell-type-specific transactivation of the parathyroid hormone-related protein gene promoter by the human T-cell leukemia virus type I (HTLV-I) tax and HTLV-II tax proteins.
Blood 1993;81(4):1017-24.
1992: Kathleen M Sakamoto; Stephen D Nimer; Joseph D Rosenblatt; Judith C Gasson
HTLV-I and HTLV-II tax trans-activate the human EGR-1 promoter through different cis-acting sequences.
Oncogene 1992;7(11):2125-30.
1992: Joseph D Rosenblatt; P Tomkins; M Rosenthal; A Kacena; G Chan; R Valderama; W Harrington; E Saxton; A Diagne; J Q Zhao
Progressive spastic myelopathy in a patient co-infected with HIV-1 and HTLV-II: autoantibodies to the human homologue of rig in blood and cerebrospinal fluid.
AIDS (London, England) 1992;6(10):1151-8.
1992: R K Wada; Robert C Seeger; Charles Patrick Reynolds; T Alloggiamento; Joyce Yamashiro; C Ruland; A C Black; Joseph D Rosenblatt
Cell type-specific expression and negative regulation by retinoic acid of the human N-myc promoter in neuroblastoma cells.
Oncogene 1992;7(4):711-7.
1992: Joseph D Rosenblatt; Y Danon; A C Black
A decade with HTLV-I/HTLV-II: lesions in viral leukemogenesis.
Leukemia 1992;6 Suppl 1():18-23.
1991: A C Black; C T Ruland; M T Yip; J Luo; B Tran; A Kalsi; E Quan; M Aboud; Irvin S Y Chen; Joseph D Rosenblatt
Human T-cell leukemia virus type II Rex binding and activity require an intact splice donor site and a specific RNA secondary structure.
Journal of virology 1991;65(12):6645-53.
1991: R H Weisbart; A L Wong; D Noritake; A Kacena; G Chan; C Ruland; E Chin; I S Chen; Joseph D Rosenblatt
The rheumatoid factor reactivity of a human IgG monoclonal autoantibody is encoded by a variant V kappa II L chain gene.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(8):2795-801.
1991: B Shohat; M Shaklai; Y Sidi; G Nadel; Joseph D Rosenblatt; D Mytes
Elevated serum interleukin-2 receptors in a newly identified group with high rates of human T cell leukemia virus type I infection in Israel.
The Journal of infectious diseases 1991;164(2):431-2.
1991: H H Lee; P Swanson; Joseph D Rosenblatt; I S Chen; W C Sherwood; D E Smith; G E Tegtmeier; L P Fernando; C T Fang; M Osame
Relative prevalence and risk factors of HTLV-I and HTLV-II infection in US blood donors.
Lancet 1991;337(8755):1435-9.
1991: M T Yip; William S Dynan; P L Green; A C Black; SJ Arrigo; A Torbati; Shaun Heaphy; C Ruland; Joseph D Rosenblatt; Irvin S Y Chen
Human T-cell leukemia virus (HTLV) type II Rex protein binds specifically to RNA sequences of the HTLV long terminal repeat but poorly to the human immunodeficiency virus type 1 Rev-responsive element.
Journal of virology 1991;65(5):2261-72.
1991: A C Black; Irvin S Y Chen; SJ Arrigo; C T Ruland; T Allogiamento; E Chin; Joseph D Rosenblatt
Regulation of HTLV-II gene expression by Rex involves positive and negative cis-acting elements in the 5'long terminal repeat.
Virology 1991;181(2):433-44.
1990: Joseph D Rosenblatt; S Plaeger-Marshall; Janis V Giorgi; P Swanson; Irvin S Y Chen; E Chin; H J Wang; M Canavaggio; Mary Ann Hausner; A C Black
A clinical, hematologic, and immunologic analysis of 21 HTLV-II-infected intravenous drug users.
Blood 1990;76(2):409-17.
1990: D M Aboulafia; E H Saxton; H Koga; A Diagne; Joseph D Rosenblatt
A patient with progressive myelopathy and antibodies to human T-cell leukemia virus type I and human immunodeficiency virus type 1 in serum and cerebrospinal fluid.
Archives of neurology 1990;47(4):477-9.
1990: Y Sidi; D Meytes; B Shohat; E Fenig; Y Weisbort; H Lee; J Pinkhas; Joseph D Rosenblatt
Adult T-cell lymphoma in Israeli patients of Iranian origin.
Cancer 1990;65(3):590-3.
1990: Joseph D Rosenblatt; Jerome A Zack; Irvin S Y Chen; H Lee
Recent advances in detection of human T-cell leukemia viruses type I and type II infection.
Natural immunity and cell growth regulation 1990;9(3):143-9.
1989: SJ Arrigo; Stacy R Weitsman; Joseph D Rosenblatt; Irvin S Y Chen
Analysis of rev gene function on human immunodeficiency virus type 1 replication in lymphoid cells by using a quantitative polymerase chain reaction method.
Journal of virology 1989;63(11):4875-81.
1989: Andras Perl; Joseph D Rosenblatt; I S Chen; J P DiVincenzo; R Bever; B J Poiesz; G N Abraham
Detection and cloning of new HTLV-related endogenous sequences in man.
Nucleic acids research 1989;17(17):6841-54.
1989: E H Saxton; H Lee; P Swanson; Irvin S Y Chen; C Ruland; E Chin; D Aboulafia; Rick B Delamarter; Joseph D Rosenblatt
Detection of human T-cell leukemia/lymphoma virus type I in a transfusion recipient with chronic myelopathy.
Neurology 1989;39(6):841-4.
1989: Stephen D Nimer; Judith C Gasson; K Hu; I Smalberg; J L Williams; Irvin S Y Chen; Joseph D Rosenblatt
Activation of the GM-CSF promoter by HTLV-I and -II tax proteins.
Oncogene 1989;4(6):671-6.
1989: H Lee; P Swanson; V S Shorty; J A Zack; Joseph D Rosenblatt; I S Chen
High rate of HTLV-II infection in seropositive i.v. drug abusers in New Orleans.
Science (New York, N.Y.) 1989;244(4903):471-5.
1989: AJ Cann; Joseph D Rosenblatt; W Wachsman; Irvin S Y Chen
In vitro mutagenesis of the human T-cell leukemia virus types I and II tax genes.
Journal of virology 1989;63(3):1474-9.
1988: Joseph D Rosenblatt; Irvin S Y Chen; W Wachsman
Infection with HTLV-I and HTLV-II: evolving concepts.
Seminars in hematology 1988;25(3):230-46.
1988: Joseph D Rosenblatt; AJ Cann; Dennis J Slamon; I S Smalberg; N P Shah; J Fujii; W Wachsman; Irvin S Y Chen
HTLV-II transactivation is regulated by the overlapping tax/rex nonstructural genes.
Science (New York, N.Y.) 1988;240(4854):916-9.
1988: Joseph D Rosenblatt; Irvin S Y Chen; David W Golde
HTLV-II and human lymphoproliferative disorders.
Clinics in laboratory medicine 1988;8(1):85-95.
1988: Joseph D Rosenblatt; Janis V Giorgi; David W Golde; J B Ezra; A Wu; C D Winberg; J Glaspy; W Wachsman; Irvin S Y Chen
Integrated human T-cell leukemia virus II genome in CD8 + T cells from a patient with "atypical" hairy cell leukemia: evidence for distinct T and B cell lymphoproliferative disorders.
Blood 1988;71(2):363-9.
1987: M Aboud; D W Golde; N Bersch; Joseph D Rosenblatt; I S Chen
A colony assay for in vitro transformation by human T cell leukemia viruses type I and type II.
Blood 1987;70(2):432-6.
1987: Joseph D Rosenblatt; Judith C Gasson; J Glaspy; S Bhuta; M Aboud; Irvin S Y Chen; David W Golde
Relationship between human T cell leukemia virus-II and atypical hairy cell leukemia: a serologic study of hairy cell leukemia patients.
Leukemia 1987;1(4):397-401.
1986: Joseph D Rosenblatt; David W Golde; W Wachsman; Janis V Giorgi; A Jacobs; G M Schmidt; S Quan; Judith C Gasson; Irvin S Y Chen
A second isolate of HTLV-II associated with atypical hairy-cell leukemia.
The New England journal of medicine 1986;315(6):372-7.
1986: Irvin S Y Chen; W Wachsman; Joseph D Rosenblatt; AJ Cann
The role of the x gene in HTLV associated malignancy.
Cancer surveys 1986;5(2):329-42.
1985: AJ Cann; Joseph D Rosenblatt; W Wachsman; N P Shah; Irvin S Y Chen
Identification of the gene responsible for human T-cell leukaemia virus transcriptional regulation.
Nature 1985;318(6046):571-4.
1985: Irvin S Y Chen; Dennis J Slamon; Joseph D Rosenblatt; N P Shah; S G Quan; W Wachsman
The x gene is essential for HTLV replication.
Science (New York, N.Y.) 1985;229(4708):54-8.
1984: Joseph D Rosenblatt; W Wachsman; K Shimotohno; Dennis J Slamon; I S Chen
The comparative molecular biology of HTLV-I and HTLV-II.
Princess Takamatsu symposia 1984;15():177-85.
1982: J P Crowe; C A Hubay; O H Pearson; J S Marshall; Joseph D Rosenblatt; E G Mansour; R E Hermann; J C Jones; W J Flynn; W L McGuire
Estrogen receptor status as a prognostic indicator for stage I breast cancer patients.
Breast cancer research and treatment 1982;2(2):171-6.
1981: C A Hubay; O H Pearson; J S Marshall; T A Stellato; R S Rhodes; S M DeBanne; Joseph D Rosenblatt; E G Mansour; R E Hermann; J C Jones; W J Flynn; C Eckert; W L McGuire
Adjuvant therapy of stage II breast cancer: 48-month follow-up of a prospective randomized clinical trial.
Breast cancer research and treatment 1981;1(1):77-82.
1980: C A Hubay; O H Pearson; J S Marshall; R S Rhodes; S M DeBanne; Joseph D Rosenblatt; E G Mansour; R E Hermann; J C Jones; W J Flynn; C Eckert; W L McGuire
Adjuvant chemotherapy, antiestrogen therapy and immunotherapy for stage II breast cancer: 45-month follow-up of a prospective, randomized clinical trial.
Cancer 1980;46(12 Suppl):2805-8.
1977: Joseph D Rosenblatt; P M Zeltzer; J Portaro; Robert C Seeger
Inhibition of antibody-dependent cellular cytotoxicity by protein A from Staphylococcus aureus.
Journal of immunology (Baltimore, Md. : 1950) 1977;118(3):981-5.