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Floris Bikker

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Living Beings

Streptococcus mutans

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Anatomy

Procedures

Physiology

Gene Expression Regulation, Neoplastic

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Publications

TOP 3
Tjitske Sijbrandij; Enno C I Veerman; Nivedita Cukkemane; Kamran Nazmi; Floris J Bikker
Sortase a as a tool to functionalize surfaces.
Floris J Bikker; W E Kaman; Enno C I Veerman
[Dextrorotary protease substrates could be suitable for oral microbiological diagnostics].
Floris J Bikker; Nivedita Cukkemane; Kamran Nazmi; Enno C I Veerman
Identification of the hydroxyapatite-binding domain of salivary agglutinin.

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All Publications

2013: Tjitske Sijbrandij; Enno C I Veerman; Nivedita Cukkemane; Kamran Nazmi; Floris J Bikker
Sortase a as a tool to functionalize surfaces.
Bioconjugate chemistry 2013;24(5):828-31.
2013: Floris J Bikker; W E Kaman; Enno C I Veerman
[Dextrorotary protease substrates could be suitable for oral microbiological diagnostics].
Nederlands tijdschrift voor tandheelkunde 2013;120(3):164-7.
2013: Floris J Bikker; Nivedita Cukkemane; Kamran Nazmi; Enno C I Veerman
Identification of the hydroxyapatite-binding domain of salivary agglutinin.
European journal of oral sciences 2013;121(1):7-12.
2012: F Galassi; W E Kaman; M L Laine; D Anssari Moin; Floris J Bikker; W Crielaard; J van der Horst; E C I Veerman; D Wismeijer; Bruno G Loos
Comparing culture, real-time PCR and fluorescence resonance energy transfer technology for detection of Porphyromonas gingivalis in patients with or without peri-implant infections.
Journal of periodontal research 2012;47(5):616-25.
2011: Albert van Dijk; Edwin J A Veldhuizen; P-L Yu; Floris J Bikker; E M Molhoek; Henk P Haagsman
Avian cathelicidins: paradigms for the development of anti-infectives.
Veterinary microbiology 2011;153(1-2):27-36.
2011: E Margo Molhoek; Albert van Dijk; Edwin J A Veldhuizen; Henk P Haagsman; Floris J Bikker
A cathelicidin-2-derived peptide effectively impairs Staphylococcus epidermidis biofilms.
International journal of antimicrobial agents 2011;37(5):476-9.
2011: E Margo Molhoek; Albert van Dijk; Edwin J A Veldhuizen; Henk P Haagsman; Floris J Bikker
Improved proteolytic stability of chicken cathelicidin-2 derived peptides by D-amino acid substitutions and cyclization.
Peptides 2011;32(5):875-80.
2011: Wendy E Kaman; Albert G Hulst; Pleunie T W van Alphen; Sanne Roffel; Marcel J van der Schans; Tod Merkel; Alex Van Belkum; Floris J Bikker
Peptide-based fluorescence resonance energy transfer protease substrates for the detection and diagnosis of Bacillus species.
Analytical chemistry 2011;83(7):2511-7.
2010: E Margo Molhoek; Albert van Dijk; Edwin J A Veldhuizen; Helma Dijk-Knijnenburg; Roos H Mars-Groenendijk; Linda C L Boele; Wendy E Kaman-van Zanten; Henk P Haagsman; Floris J Bikker
Chicken cathelicidin-2-derived peptides with enhanced immunomodulatory and antibacterial activities against biological warfare agents.
International journal of antimicrobial agents 2010;36(3):271-4.
2009: E Margo Molhoek; Alice L den Hertog; Anne-Marij B C de Vries; Kamran Nazmi; Enno C I Veerman; Franca C Hartgers; Maria Yazdanbakhsh; Floris J Bikker; Desiree van der Kleij
Structure-function relationship of the human antimicrobial peptide LL-37 and LL-37 fragments in the modulation of TLR responses.
Biological chemistry 2009;390(4):295-303.
2009: Caroline End; Floris J Bikker; Marcus Renner; Gaby Bergmann; Stefan Lyer; Stephanie Blaich; Melanie Hudler; Burkhard Helmke; Nikolaus Gassler; Frank Autschbach; Antoon J M Ligtenberg; Axel Benner; Uffe Holmskov; Peter Schirmacher; Arie V Nieuw Amerongen; Philip Rosenstiel; Christian Sina; Andre Franke; Mathias Hafner; Petra Kioschis; Stefan Schreiber; Annemarie Poustka; Jan Mollenhauer
DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands.
European journal of immunology 2009;39(3):833-42.
2007: Marcus Renner; Gaby Bergmann; Inge Krebs; Caroline End; Stefan Lyer; Frank Hilberg; Burkhard Helmke; Nikolaus Gassler; Frank Autschbach; Floris J Bikker; Olga Strobel-Freidekind; Sabine Gronert-Sum; Axel Benner; Stephanie Blaich; Rainer Wittig; Melanie Hudler; Antoon J M Ligtenberg; Jens Madsen; Uffe Holmskov; Vito Annese; Anna Latiano; Peter Schirmacher; Arie V Nieuw Amerongen; Mauro D'Amato; Petra Kioschis; Mathias Hafner; Annemarie Poustka; Jan Mollenhauer
DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease.
Gastroenterology 2007;133(5):1499-509.
2007: Floris J Bikker; Roos H Mars-Groenendijk; Daan Noort; Alex Fidder; Govert P van der Schans
Detection of sulfur mustard adducts in human callus by phage antibodies.
Chemical biology & drug design 2007;69(5):314-20.
2006: Floris J Bikker; Wendy E Kaman-van Zanten; Anne-Marij B C de Vries-van de Ruit; Ingrid Voskamp-Visser; Peter A V van Hooft; Roos H Mars-Groenendijk; Peter C de Visser; Daan Noort
Evaluation of the antibacterial spectrum of drosocin analogues.
Chemical biology & drug design 2006;68(3):148-53.
2004: Floris J Bikker; Antoon J M Ligtenberg; Caroline End; Marcus Renner; Stephanie Blaich; Stefan Lyer; Rainer Wittig; Wim van't Hof; Enno C I Veerman; Kamran Nazmi; Jolanda M A de Blieck-Hogervorst; Petra Kioschis; Arie V Nieuw Amerongen; Annemarie Poustka; Jan Mollenhauer
Bacteria binding by DMBT1/SAG/gp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains.
The Journal of biological chemistry 2004;279(46):47699-703.
2004: Takahiko Oho; Floris J Bikker; Arie V Nieuw Amerongen; Jasper Groenink
A peptide domain of bovine milk lactoferrin inhibits the interaction between streptococcal surface protein antigen and a salivary agglutinin peptide domain.
Infection and immunity 2004;72(10):6181-4.
2004: Antoon J M Ligtenberg; Floris J Bikker; Jolanda M A de Blieck-Hogervorst; Enno C I Veerman; Arie V Nieuw Amerongen
Binding of salivary agglutinin to IgA.
The Biochemical journal 2004;383(Pt 1):159-64.
2004: Floris J Bikker; Jacqueline E van der Wal; Antoon J M Ligtenberg; Jan Mollenhauer; Jolanda M A de Blieck-Hogervorst; I van der Waal; Annemarie Poustka; Arie V Nieuw Amerongen
Salivary agglutinin/DMBT1SAG expression is up-regulated in the presence of salivary gland tumors.
Journal of dental research 2004;83(7):567-71.
2004: Jan Mollenhauer; Burkhard Helmke; Daniel Medina; Gaby Bergmann; Nikolaus Gassler; Hanna Müller; Stefan Lyer; Laura Diedrichs; Marcus Renner; Rainer Wittig; Stephanie Blaich; Ute Hamann; Jens Madsen; Uffe Holmskov; Floris J Bikker; Antoon J M Ligtenberg; Anette Carlén; Jan Olsson; Herwart F Otto; Bert O'Malley; Annemarie Poustka
Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis.
Genes, chromosomes & cancer 2004;39(3):185-94.
2003: Jan Mollenhauer; Martin Deichmann; Burkhard Helmke; Hanna Müller; Gaby Kollender; Uffe Holmskov; Toon Ligtenberg; Inge Krebs; Stefan Wiemann; Ursula Bantel-Schaal; Jens Madsen; Floris J Bikker; Sabine M Klauck; Herwart F Otto; Gerhard Moldenhauer; Annemarie Poustka
Frequent downregulation of DMBT1 and galectin-3 in epithelial skin cancer.
International journal of cancer. Journal international du cancer 2003;105(2):149-57.
2002: Jan Mollenhauer; Hanna Müller; Gaby Kollender; Stefan Lyer; Laura Diedrichs; Burkhard Helmke; Uffe Holmskov; Toon Ligtenberg; Stephan Herbertz; Inge Krebs; Jens Madsen; Floris J Bikker; Liane Schmitt; Stefan Wiemann; Wolfram Scheurlen; Herwart F Otto; Andreas von Deimling; Annemarie Poustka
The SRCR/SID region of DMBT1 defines a complex multi-allele system representing the major basis for its variability in cancer.
Genes, chromosomes & cancer 2002;35(3):242-55.
2002: Jan Mollenhauer; Burkhard Helmke; Hanna Müller; Gaby Kollender; Stefan Lyer; Laura Diedrichs; Uffe Holmskov; Toon Ligtenberg; Stephan Herbertz; Inge Krebs; Stefan Wiemann; Jens Madsen; Floris J Bikker; Liane Schmitt; Herwart F Otto; Annemarie Poustka
Sequential changes of the DMBT1 expression and location in normal lung tissue and lung carcinomas.
Genes, chromosomes & cancer 2002;35(2):164-9.
2002: Floris J Bikker; Antoon J M Ligtenberg; Kamran Nazmi; Enno C I Veerman; Wim van't Hof; Jan G M Bolscher; Annemarie Poustka; Arie V Nieuw Amerongen; Jan Mollenhauer
Identification of the bacteria-binding peptide domain on salivary agglutinin (gp-340/DMBT1), a member of the scavenger receptor cysteine-rich superfamily.
The Journal of biological chemistry 2002;277(35):32109-15.
2002: Floris J Bikker; Antoon J M Ligtenberg; Jacqueline E van der Wal; P A M van den Keijbus; Uffe Holmskov; Enno C I Veerman; Arie V Nieuw Amerongen
Immunohistochemical detection of salivary agglutinin/gp-340 in human parotid, submandibular, and labial salivary glands.
Journal of dental research 2002;81(2):134-9.
2001: Toon Ligtenberg; Floris J Bikker; Jasper Groenink; Ida Tornoe; Rikke Leth-Larsen; Enno C I Veerman; Arie V Nieuw Amerongen; Uffe Holmskov
Human salivary agglutinin binds to lung surfactant protein-D and is identical with scavenger receptor protein gp-340.
The Biochemical journal 2001;359(Pt 1):243-8.