Daniel Bikle

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TOP 3
Bikle Daniel D
Vitamin D and immune function: understanding common pathways.
Pao Vivian Y; Chang Sandra; Shoback Dolores M; Bikle Daniel D
Hypercalcemia and overexpression of CYP27B1 in a patient with nephrogenic systemic fibrosis: clinical vignette and literature review.
Oda Yuko; Uchida Yoshikazu; Moradian Sam; Crumrine Debra; Elias Peter M; Bikle Daniel D
Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation.

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All Publications

2009: Bikle Daniel D
Vitamin D and immune function: understanding common pathways.
Current osteoporosis reports 2009;7(2):58-63.
2009: Pao Vivian Y; Chang Sandra; Shoback Dolores M; Bikle Daniel D
Hypercalcemia and overexpression of CYP27B1 in a patient with nephrogenic systemic fibrosis: clinical vignette and literature review.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009;24(6):1135-9.
2009: Oda Yuko; Uchida Yoshikazu; Moradian Sam; Crumrine Debra; Elias Peter M; Bikle Daniel D
Vitamin D receptor and coactivators SRC2 and 3 regulate epidermis-specific sphingolipid production and permeability barrier formation.
The Journal of investigative dermatology 2009;129(6):1367-78.
2009: Xie Zhongjian; Chang Sandra M; Pennypacker Sally D; Liao Er-Yuan; Bikle Daniel D
Phosphatidylinositol-4-phosphate 5-kinase 1alpha mediates extracellular calcium-induced keratinocyte differentiation.
Molecular biology of the cell 2009;20(6):1695-704.
2009: Teichert Arnaud; Arnold Leggy A; Otieno Steve; Oda Yuko; Augustinaite Indre; Geistlinger Tim R; Kriwacki Richard W; Guy R Kiplin; Bikle Daniel D
Quantification of the vitamin D receptor-coregulator interaction.
Biochemistry 2009;48(7):1454-61.
2008: Bikle Daniel D
Vitamin D receptor, UVR, and skin cancer: a potential protective mechanism.
The Journal of investigative dermatology 2008;128(10):2357-61.
2008: Bikle D D
Integrins, insulin like growth factors, and the skeletal response to load.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2008;19(9):1237-46.
2008: Bikle Daniel D
Vitamin D and the immune system: role in protection against bacterial infection.
Current opinion in nephrology and hypertension 2008;17(4):348-52.
2008: Bikle Daniel D
Growth hormone/insulin-like growth factor-1/PTH axis in bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2008;23(5):581-3.
2008: Schauber Jürgen; Oda Yuko; Büchau Amanda S; Yun Qian-Chun; Steinmeyer Andreas; Zügel Ulrich; Bikle Daniel D; Gallo Richard L
Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3.
The Journal of investigative dermatology 2008;128(4):816-24.
2008: Tu Chia-Ling; Chang Wenhan; Xie Zhongjian; Bikle Daniel D
Inactivation of the calcium sensing receptor inhibits E-cadherin-mediated cell-cell adhesion and calcium-induced differentiation in human epidermal keratinocytes.
The Journal of biological chemistry 2008;283(6):3519-28.
2007: Bikle Daniel D
Vitamin D insufficiency/deficiency in gastrointestinal disorders.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22 Suppl 2():V50-4.
2007: Wang Yongmei; Nishida Shigeki; Boudignon Benjamin M; Burghardt Andrew; Elalieh Hashem Z; Hamilton Michelle M; Majumdar Sharmila; Halloran Bernard P; Clemens Thomas L; Bikle Daniel D
IGF-I receptor is required for the anabolic actions of parathyroid hormone on bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22(9):1329-37.
2007: Bikle Daniel D
What is new in vitamin D: 2006-2007.
Current opinion in rheumatology 2007;19(4):383-8.
2007: Dvorak Melita M; Chen Tsui-Hua; Orwoll Benjamin; Garvey Caitlin; Chang Wenhan; Bikle Daniel D; Shoback Dolores M
Constitutive activity of the osteoblast Ca2+-sensing receptor promotes loss of cancellous bone.
Endocrinology 2007;148(7):3156-63.
2007: Boudignon Benjamin M; Bikle Daniel D; Kurimoto Pam; Elalieh Hashem; Nishida Shigeki; Wang Yongmei; Burghardt Andrew; Majumdar Sharmila; Orwoll Benjamin E; Rosen Clifford; Halloran Bernard P
Insulin-like growth factor I stimulates recovery of bone lost after a period of skeletal unloading.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;103(1):125-31.
2007: Tu Chia-Ling; Chang Wenhan; Bikle Daniel D
The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes.
The Journal of investigative dermatology 2007;127(5):1074-83.
2007: Hawker Nathaniel P; Pennypacker Sally D; Chang Sandra M; Bikle Daniel D
Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3.
The Journal of investigative dermatology 2007;127(4):874-80.
2007: Schauber Jürgen; Dorschner Robert A; Coda Alvin B; Büchau Amanda S; Liu Philip T; Kiken David; Helfrich Yolanda R; Kang Sewon; Elalieh Hashem Z; Steinmeyer Andreas; Zügel Ulrich; Bikle Daniel D; Modlin Robert L; Gallo Richard L
Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism.
The Journal of clinical investigation 2007;117(3):803-11.
2007: Xie Zhongjian; Bikle Daniel D
The recruitment of phosphatidylinositol 3-kinase to the E-cadherin-catenin complex at the plasma membrane is required for calcium-induced phospholipase C-gamma1 activation and human keratinocyte differentiation.
The Journal of biological chemistry 2007;282(12):8695-703.
2007: Oda Yuko; Ishikawa Mieko H; Hawker Nathaniel P; Yun Qian-Chun; Bikle Daniel D
Differential role of two VDR coactivators, DRIP205 and SRC-3, in keratinocyte proliferation and differentiation.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):776-80.
2007: Burghardt Andrew J; Wang Yongmei; Elalieh Hashem; Thibault Xavier; Bikle Daniel; Peyrin Françoise; Majumdar Sharmila
Evaluation of fetal bone structure and mineralization in IGF-I deficient mice using synchrotron radiation microtomography and Fourier transform infrared spectroscopy.
Bone 2007;40(1):160-8.
2006: Wang Yongmei; Nishida Shigeki; Sakata Takeshi; Elalieh Hashem Z; Chang Wenhan; Halloran Bernard P; Doty Steven B; Bikle Daniel D
Insulin-like growth factor-I is essential for embryonic bone development.
Endocrinology 2006;147(10):4753-61.
2006: Wang Yongmei; Nishida Shigeki; Elalieh Hashem Z; Long Roger K; Halloran Bernard P; Bikle Daniel D
Role of IGF-I signaling in regulating osteoclastogenesis.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(9):1350-8.
2006: Wang Yongmei; Sakata Takeshi; Elalieh Hashem Z; Munson Scott J; Burghardt Andrew; Majumdar Sharmila; Halloran Bernard P; Bikle Daniel D
Gender differences in the response of CD-1 mouse bone to parathyroid hormone: potential role of IGF-I.
The Journal of endocrinology 2006;189(2):279-87.
2006: Bikle Daniel D; Elalieh Hashem; Chang Sandra; Xie Zhongjian; Sundberg John P
Development and progression of alopecia in the vitamin D receptor null mouse.
Journal of cellular physiology 2006;207(2):340-53.
2006: Xie Zhongjian; Chang Sandra; Oda Yuko; Bikle Daniel D
Hairless suppresses vitamin D receptor transactivation in human keratinocytes.
Endocrinology 2006;147(1):314-23.
2005: Rodriguez Luis; Tu Chialing; Cheng Zhiqiang; Chen Tsui-Hua; Bikle Daniel; Shoback Dolores; Chang Wenhan
Expression and functional assessment of an alternatively spliced extracellular Ca2+-sensing receptor in growth plate chondrocytes.
Endocrinology 2005;146(12):5294-303.
2005: Bikle Daniel D; Oda Yuko; Xie Zhongian
Vitamin D and skin cancer: a problem in gene regulation.
The Journal of steroid biochemistry and molecular biology 2005;97(1-2):83-91.
2005: Xie Zhongjian; Singleton Patrick A; Bourguignon Lilly Y W; Bikle Daniel D
Calcium-induced human keratinocyte differentiation requires src- and fyn-mediated phosphatidylinositol 3-kinase-dependent activation of phospholipase C-gamma1.
Molecular biology of the cell 2005;16(7):3236-46.
2005: Tu Chia-Ling; Chang Wenhan; Bikle Daniel D
Phospholipase cgamma1 is required for activation of store-operated channels in human keratinocytes.
The Journal of investigative dermatology 2005;124(1):187-97.
2004: Bikle Daniel D
Vitamin D and skin cancer.
The Journal of nutrition 2004;134(12 Suppl):3472S-3478S.
2004: Schmuth Matthias; Elias Peter M; Hanley Karen; Lau Peggy; Moser A; Willson Timothy M; Bikle Daniel D; Feingold Kenneth R
The effect of LXR activators on AP-1 proteins in keratinocytes.
The Journal of investigative dermatology 2004;123(1):41-8.
2004: Bikle Daniel D
Vitamin D regulated keratinocyte differentiation.
Journal of cellular biochemistry 2004;92(3):436-44.
2004: Bikle D D; Oda Y; Xie Z
Calcium and 1,25(OH)2D: interacting drivers of epidermal differentiation.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):355-60.
2004: Bikle D D; Chang S; Crumrine D; Elalieh H; Man M-Q; Dardenne O; Xie Z; Arnaud R St; Feingold K; Elias P M
Mice lacking 25OHD 1alpha-hydroxylase demonstrate decreased epidermal differentiation and barrier function.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):347-53.
2004: Oda Yuko; Sihlbom Carina; Chalkley Robert J; Huang Lan; Rachez Christophe; Chang Chao-Pei Betty; Burlingame Alma L; Freedman Leonard P; Bikle Daniel D
Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in VDR transactivation during keratinocyte differentiation.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):273-6.
2004: Bikle D D; Chang S; Crumrine D; Elalieh H; Man M-Q; Choi E H; Dardenne O; Xie Z; Arnaud R St; Feingold K; Elias P M
25 Hydroxyvitamin D 1 alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis.
The Journal of investigative dermatology 2004;122(4):984-92.
2004: Tu Chia-Ling; Oda Yuko; Komuves Laszlo; Bikle Daniel D
The role of the calcium-sensing receptor in epidermal differentiation.
Cell calcium 2004;35(3):265-73.
2004: Sakata Takeshi; Wang Yongmei; Halloran Bernard P; Elalieh Hashem Z; Cao Jay; Bikle Daniel D
Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(3):436-46.
2004: Huang John C; Sakata Takeshi; Pfleger Laura L; Bencsik Margaret; Halloran Bernard P; Bikle Daniel D; Nissenson Robert A
PTH differentially regulates expression of RANKL and OPG.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(2):235-44.
2003: Oda Yuko; Sihlbom Carina; Chalkley Robert J; Huang Lan; Rachez Christophe; Chang Chao-Pei Betty; Burlingame Alma L; Freedman Leonard P; Bikle Daniel D
Two distinct coactivators, DRIP/mediator and SRC/p160, are differentially involved in vitamin D receptor transactivation during keratinocyte differentiation.
Molecular endocrinology (Baltimore, Md.) 2003;17(11):2329-39.
2003: Behne Martin J; Tu Chia-Ling; Aronchik Ida; Epstein Ervin; Bench Graham; Bikle Daniel D; Pozzan Tullio; Mauro Theodora M
Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores.
The Journal of investigative dermatology 2003;121(4):688-94.
2003: Bikle Daniel D; Sakata Takeshi; Halloran Bernard P
The impact of skeletal unloading on bone formation.
Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology 2003;16(2):45-54.
2003: Sakata T; Halloran B P; Elalieh H Z; Munson S J; Rudner L; Venton L; Ginzinger D; Rosen C J; Bikle D D
Skeletal unloading induces resistance to insulin-like growth factor I on bone formation.
Bone 2003;32(6):669-80.
2003: Yang Lee Chuan; Ng Dean C; Bikle Daniel D
Role of protein kinase C alpha in calcium induced keratinocyte differentiation: defective regulation in squamous cell carcinoma.
Journal of cellular physiology 2003;195(2):249-59.
2003: Dolezalova Hana; Shankar Geetha; Huang Mei-Chuan; Bikle Daniel D; Goetzl Edward J
Biochemical regulation of breast cancer cell expression of S1P2 (Edg-5) and S1P3 (Edg-3) G protein-coupled receptors for sphingosine 1-phosphate.
Journal of cellular biochemistry 2003;88(4):732-43.
2003: Bikle D D; Tu C L; Xie Z; Oda Y
Vitamin D regulated keratinocyte differentiation: role of coactivators.
Journal of cellular biochemistry 2003;88(2):290-5.
2003: Bikle Daniel D; Xie Zhongjian; Ng Dean; Tu Chia-Ling; Oda Yuko
Squamous cell carcinomas fail to respond to the prodifferentiating actions of 1,25(OH)2D: why?
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;164():111-22.
2002: Bikle Daniel D; Ng Dean; Oda Yuko; Hanley Karen; Feingold Kenneth; Xie Zhongjian
The vitamin D response element of the involucrin gene mediates its regulation by 1,25-dihydroxyvitamin D3.
The Journal of investigative dermatology 2002;119(5):1109-13.
2002: Xie Zhongjian; Munson Scott J; Huang Ningwu; Portale Anthony A; Miller Walter L; Bikle Daniel D
The mechanism of 1,25-dihydroxyvitamin D(3) autoregulation in keratinocytes.
The Journal of biological chemistry 2002;277(40):36987-90.
2002: Bikle Daniel D; Sakata Takeshi; Leary Colin; Elalieh Hashem; Ginzinger David; Rosen Clifford J; Beamer Wesley; Majumdar Sharmila; Halloran Bernard P
Insulin-like growth factor I is required for the anabolic actions of parathyroid hormone on mouse bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(9):1570-8.
2002: Komuves Laszlo; Oda Yuko; Tu Chia-Ling; Chang Wen Han; Ho-Pao Chrystal L; Mauro Theodora; Bikle Daniel D
Epidermal expression of the full-length extracellular calcium-sensing receptor is required for normal keratinocyte differentiation.
Journal of cellular physiology 2002;192(1):45-54.
2002: Xie Zhongjion; Komuves László; Yu Qian-Chun; Elalieh Hashem; Ng Dean C; Leary Colin; Chang Sandra; Crumrine Debra; Yoshizawa Tatsuya; Kato Shigeaki; Bikle Daniel D
Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth.
The Journal of investigative dermatology 2002;118(1):11-6.
2001: Bikle D; Majumdar S; Laib A; Powell-Braxton L; Rosen C; Beamer W; Nauman E; Leary C; Halloran B
The skeletal structure of insulin-like growth factor I-deficient mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(12):2320-9.
2001: Xie Z; Bikle D D
Inhibition of 1,25-dihydroxyvitamin-D-induced keratinocyte differentiation by blocking the expression of phospholipase C-gamma1.
The Journal of investigative dermatology 2001;117(5):1250-4.
2001: Tu C L; Chang W; Bikle D D
The extracellular calcium-sensing receptor is required for calcium-induced differentiation in human keratinocytes.
The Journal of biological chemistry 2001;276(44):41079-85.
2001: Bikle D D; Ng D; Tu C L; Oda Y; Xie Z
Calcium- and vitamin D-regulated keratinocyte differentiation.
Molecular and cellular endocrinology 2001;177(1-2):161-71.
2001: Hanley K; Wood L; Ng D C; He S S; Lau P; Moser A; Elias P M; Bikle D D; Williams M L; Feingold K R
Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D.
Journal of lipid research 2001;42(3):390-8.
2001: Xie Z; Bikle D D
The role of phospholipase C-gamma1 in 1alpha,25-dihydroxyvitamin D(3) regulated keratinocyte differentiation.
Steroids 2001;66(3-5):339-45.
2000: Kömüves L G; Hanley K; Lefebvre A M; Man M Q; Ng D C; Bikle D D; Williams M L; Elias P M; Auwerx J; Feingold K R
Stimulation of PPARalpha promotes epidermal keratinocyte differentiation in vivo.
The Journal of investigative dermatology 2000;115(3):353-60.
2000: Ng D C; Shafaee S; Lee D; Bikle D D
Requirement of an AP-1 site in the calcium response region of the involucrin promoter.
The Journal of biological chemistry 2000;275(31):24080-8.
2000: Hanley K; Kömüves L G; Ng D C; Schoonjans K; He S S; Lau P; Bikle D D; Williams M L; Elias P M; Auwerx J; Feingold K R
Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha.
The Journal of biological chemistry 2000;275(15):11484-91.
2000: Hanley K; Ng D C; He S S; Lau P; Min K; Elias P M; Bikle D D; Mangelsdorf D J; Williams M L; Feingold K R
Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription.
The Journal of investigative dermatology 2000;114(3):545-53.
2000: Oda Y; Tu C L; Chang W; Crumrine D; Kömüves L; Mauro T; Elias P M; Bikle D D
The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation.
The Journal of biological chemistry 2000;275(2):1183-90.
1999: Tu C L; Oda Y; Bikle D D
Effects of a calcium receptor activator on the cellular response to calcium in human keratinocytes.
The Journal of investigative dermatology 1999;113(3):340-5.
1999: Xie Z; Bikle D D
Phospholipase C-gamma1 is required for calcium-induced keratinocyte differentiation.
The Journal of biological chemistry 1999;274(29):20421-4.
1999: Ratnam A V; Bikle D D; Cho J K
1,25 dihydroxyvitamin D3 enhances the calcium response of keratinocytes.
Journal of cellular physiology 1999;178(2):188-96.
1999: Kostenuik P J; Harris J; Halloran B P; Turner R T; Morey-Holton E R; Bikle D D
Skeletal unloading causes resistance of osteoprogenitor cells to parathyroid hormone and to insulin-like growth factor-I.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(1):21-31.
1999: Dehority W; Halloran B P; Bikle D D; Curren T; Kostenuik P J; Wronski T J; Shen Y; Rabkin B; Bouraoui A; Morey-Holton E
Bone and hormonal changes induced by skeletal unloading in the mature male rat.
The American journal of physiology 1999;276(1 Pt 1):E62-9.
1999: Khoroshev M I; Munson S J; Bikle D D
Six putative IQ motifs of the recombinant chicken intestinal brush border myosin I are involved in calmodulin binding.
Archives of biochemistry and biophysics 1999;361(1):94-100.
1998: Oda Y; Tu C L; Pillai S; Bikle D D
The calcium sensing receptor and its alternatively spliced form in keratinocyte differentiation.
The Journal of biological chemistry 1998;273(36):23344-52.
1998: Xie Z; Bikle D D
Differential regulation of vitamin D responsive elements in normal and transformed keratinocytes.
The Journal of investigative dermatology 1998;110(5):730-3.
1998: Hanley K; Jiang Y; He S S; Friedman M; Elias P M; Bikle D D; Williams M L; Feingold K R
Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPARalpha.
The Journal of investigative dermatology 1998;110(4):368-75.
1997: Kostenuik P J; Halloran B P; Morey-Holton E R; Bikle D D
Skeletal unloading inhibits the in vitro proliferation and differentiation of rat osteoprogenitor cells.
The American journal of physiology 1997;273(6 Pt 1):E1133-9.
1997: Fu G K; Lin D; Zhang M Y; Bikle D D; Shackleton C H; Miller W L; Portale A A
Cloning of human 25-hydroxyvitamin D-1 alpha-hydroxylase and mutations causing vitamin D-dependent rickets type 1.
Molecular endocrinology (Baltimore, Md.) 1997;11(13):1961-70.
1997: Cho J K; Bikle D D
Decrease of Ca(2+)-ATPase activity in human keratinocytes during calcium-induced differentiation.
Journal of cellular physiology 1997;172(2):146-54.
1997: Halloran B P; Bikle D D; Harris J; Tanner S; Curren T; Morey-Holton E
Regional responsiveness of the tibia to intermittent administration of parathyroid hormone as affected by skeletal unloading.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(7):1068-74.
1997: Bikle D D; Halloran B P; Morey-Holton E
Spaceflight and the skeleton: lessons for the earthbound.
Gravitational and space biology bulletin : publication of the American Society for Gravitational and Space Biology 1997;10(2):119-35.
1997: Xie Z; Bikle D D
Cloning of the human phospholipase C-gamma1 promoter and identification of a DR6-type vitamin D-responsive element.
The Journal of biological chemistry 1997;272(10):6573-7.
1997: Bikle D D; Halloran B P; Morey-Holton E
Space flight and the skeleton: lessons for the earthbound.
The Endocrinologist 1997;7(1):10-22.
1996: Love-Schimenti C D; Gibson D F; Ratnam A V; Bikle D D
Antiestrogen potentiation of antiproliferative effects of vitamin D3 analogues in breast cancer cells.
Cancer research 1996;56(12):2789-94.
1996: Bikle D D
1,25(OH)2D3-modulated calcium induced keratinocyte differentiation.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1996;1(1):22-7.
1996: Bikle D D; Munson S; Komuves L
Zipper protein, a B-G protein with the ability to regulate actin/myosin 1 interactions in the intestinal brush border.
The Journal of biological chemistry 1996;271(15):9075-83.
1996: Ratnam A V; Bikle D D; Su M J; Pillai S
Squamous carcinoma cell lines fail to respond to 1,25-Dihydroxyvitamin D despite normal levels of the vitamin D receptor.
The Journal of investigative dermatology 1996;106(3):522-5.
1996: Bikle D D; Ratnam A; Mauro T; Harris J; Pillai S
Changes in calcium responsiveness and handling during keratinocyte differentiation. Potential role of the calcium receptor.
The Journal of clinical investigation 1996;97(4):1085-93.
1996: Gibson D F; Ratnam A V; Bikle D D
Evidence for separate control mechanisms at the message, protein, and enzyme activation levels for transglutaminase during calcium-induced differentiation of normal and transformed human keratinocytes.
The Journal of investigative dermatology 1996;106(1):154-61.
1995: Halloran B P; Bikle D D; Harris J; Autry C P; Currier P A; Tanner S; Patterson-Buckendahl P; Morey-Holton E
Skeletal unloading induces selective resistance to the anabolic actions of growth hormone on bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(8):1168-76.
1995: Pillai S; Bikle D D; Su M J; Ratnam A; Abe J
1,25-Dihydroxyvitamin D3 upregulates the phosphatidylinositol signaling pathway in human keratinocytes by increasing phospholipase C levels.
The Journal of clinical investigation 1995;96(1):602-9.
1995: Bikle D D; Harris J; Halloran B P; Currier P A; Tanner S; Morey-Holton E
The molecular response of bone to growth hormone during skeletal unloading: regional differences.
Endocrinology 1995;136(5):2099-109.
1994: Bikle D D; Harris J; Halloran B P; Morey-Holton E
Altered skeletal pattern of gene expression in response to spaceflight and hindlimb elevation.
The American journal of physiology 1994;267(6 Pt 1):E822-7.
1994: Bikle D D; Morey-Holton E R; Doty S B; Currier P A; Tanner S J; Halloran B P
Alendronate increases skeletal mass of growing rats during unloading by inhibiting resorption of calcified cartilage.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(11):1777-87.
1994: Bikle D D
Role of vitamin D, its metabolites, and analogs in the management of osteoporosis.
Rheumatic diseases clinics of North America 1994;20(3):759-75.
1994: Su M J; Bikle D D; Mancianti M L; Pillai S
1,25-Dihydroxyvitamin D3 potentiates the keratinocyte response to calcium.
The Journal of biological chemistry 1994;269(20):14723-9.
1994: Kaune R; Munson S; Bikle D D
Regulation of calmodulin binding to the ATP extractable 110 kDa protein (myosin I) from chicken duodenal brush border by 1,25-(OH)2D3.
Biochimica et biophysica acta 1994;1190(2):329-36.
1993: Bikle D D; Gee E; Pillai S
Regulation of keratinocyte growth, differentiation, and vitamin D metabolism by analogs of 1,25-dihydroxyvitamin D.
The Journal of investigative dermatology 1993;101(5):713-8.
1993: Halloran B P; Bikle D D; Harris J; Foskett H C; Morey-Holton E
Skeletal unloading decreases production of 1,25-dihydroxyvitamin D.
The American journal of physiology 1993;264(5 Pt 1):E712-6.
1993: Bikle D D; Munson S; Morrison N; Eisman J
Zipper protein, a newly described tropomyosin-like protein of the intestinal brush border.
The Journal of biological chemistry 1993;268(1):620-6.
1992: Portale A A; Halloran B P; Harris S T; Bikle D D; Morris R C
Metabolic acidosis reverses the increase in serum 1,25(OH)2D in phosphorus-restricted normal men.
The American journal of physiology 1992;263(6 Pt 1):E1164-70.
1992: Pillai S; Bikle D D
Adenosine triphosphate stimulates phosphoinositide metabolism, mobilizes intracellular calcium, and inhibits terminal differentiation of human epidermal keratinocytes.
The Journal of clinical investigation 1992;90(1):42-51.
1992: Pillai S; Bikle D D
Lanthanum influx into cultured human keratinocytes: effect on calcium flux and terminal differentiation.
Journal of cellular physiology 1992;151(3):623-9.
1991: Bikle D D; Pillai S; Gee E
Squamous carcinoma cell lines produce 1,25 dihydroxyvitamin D, but fail to respond to its prodifferentiating effect.
The Journal of investigative dermatology 1991;97(3):435-41.
1991: Bikle D D; Pillai S; Gee E; Hincenbergs M
Tumor necrosis factor-alpha regulation of 1,25-dihydroxyvitamin D production by human keratinocytes.
Endocrinology 1991;129(1):33-8.
1991: Pillai S; Bikle D D; Mancianti M L; Hincenbergs M
Uncoupling of the calcium-sensing mechanism and differentiation in squamous carcinoma cell lines.
Experimental cell research 1991;192(2):567-73.
1991: Pillai S; Bikle D D
Role of intracellular-free calcium in the cornified envelope formation of keratinocytes: differences in the mode of action of extracellular calcium and 1,25 dihydroxyvitamin D3.
Journal of cellular physiology 1991;146(1):94-100.
1990: Bikle D D; Halloran B P; McGalliard-Cone C; Morey-Holton E
Different responses of trabecular and cortical bone to 1,25(OH)2D3 infusion.
The American journal of physiology 1990;259(5 Pt 1):E715-22.
1990: Pillai S; Bikle D D; Mancianti M L; Cline P; Hincenbergs M
Calcium regulation of growth and differentiation of normal human keratinocytes: modulation of differentiation competence by stages of growth and extracellular calcium.
Journal of cellular physiology 1990;143(2):294-302.
1989: Patterson-Buckendahl P; Globus R K; Bikle D D; Cann C E; Morey-Holton E
Effects of simulated weightlessness on rat osteocalcin and bone calcium.
The American journal of physiology 1989;257(5 Pt 2):R1103-9.
1989: Sessions N D; Halloran B P; Bikle D D; Wronski T J; Cone C M; Morey-Holton E
Bone response to normal weight bearing after a period of skeletal unloading.
The American journal of physiology 1989;257(4 Pt 1):E606-10.
1989: Halloran B P; Bikle D D; Castro M E; Gee E
Isotopic labeling affects 1,25-dihydroxyvitamin D metabolism.
Biochemistry 1989;28(3):1278-81.
1989: Bikle D D; Pillai S; Gee E; Hincenbergs M
Regulation of 1,25-dihydroxyvitamin D production in human keratinocytes by interferon-gamma.
Endocrinology 1989;124(2):655-60.
1989: Bikle D D; Gee E
Free, and not total, 1,25-dihydroxyvitamin D regulates 25-hydroxyvitamin D metabolism by keratinocytes.
Endocrinology 1989;124(2):649-54.
1989: Bikle D; Munson S; Christakos S; Kumar R; Buckendahl P
Calmodulin binding to the intestinal brush-border membrane: comparison to other calcium-binding proteins.
Biochimica et biophysica acta 1989;1010(1):122-7.
1988: Halloran B P; Bikle D D; Cone C M; Morey-Holton E
Glucocorticoids and inhibition of bone formation induced by skeletal unloading.
The American journal of physiology 1988;255(6 Pt 1):E875-9.
1987: Bikle D D; Halloran B P; Cone C M; Globus R K; Morey-Holton E
The effects of simulated weightlessness on bone maturation.
Endocrinology 1987;120(2):678-84.
1986: Wronski T J; Halloran B P; Bikle D D; Globus R K; Morey-Holton E R
Chronic administration of 1,25-dihydroxyvitamin D3: increased bone but impaired mineralization.
Endocrinology 1986;119(6):2580-5.
1986: Bikle D D; Gee E; Halloran B; Kowalski M A; Ryzen E; Haddad J G
Assessment of the free fraction of 25-hydroxyvitamin D in serum and its regulation by albumin and the vitamin D-binding protein.
The Journal of clinical endocrinology and metabolism 1986;63(4):954-9.
1986: Bikle D D; Halloran B P; Gee E; Ryzen E; Haddad J G
Free 25-hydroxyvitamin D levels are normal in subjects with liver disease and reduced total 25-hydroxyvitamin D levels.
The Journal of clinical investigation 1986;78(3):748-52.
1986: Halloran B P; Bikle D D; Levens M J; Castro M E; Globus R K; Holton E
Chronic 1,25-dihydroxyvitamin D3 administration in the rat reduces the serum concentration of 25-hydroxyvitamin D by increasing metabolic clearance rate.
The Journal of clinical investigation 1986;78(3):622-8.
1986: Globus R K; Bikle D D; Halloran B; Morey-Holton E
Skeletal response to dietary calcium in a rat model simulating weightlessness.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1986;1(2):191-7.
1986: Halloran B P; Bikle D D; Wronski T J; Globus R K; Levens M J; Morey-Holton E
The role of 1,25-dihydroxyvitamin D in the inhibition of bone formation induced by skeletal unloading.
Endocrinology 1986;118(3):948-54.
1986: Globus R K; Bikle D D; Morey-Holton E
The temporal response of bone to unloading.
Endocrinology 1986;118(2):733-42.
1985: Halloran B P; Bikle D D; Wronski T J; Globus R K; Levens M J; Morey-Holton E
Effect of simulated weightlessness and chronic 1,25-dihydroxyvitamin D administration on bone metabolism.
The Physiologist 1985;28(6 Suppl):S127-8.
1985: Bikle D D; Halloran B P; Cone C M; Morey-Holton E
Bone loss during simulated weightlessness: is it glucocorticoid mediated?
The Physiologist 1985;28(6 Suppl):S123-4.
1985: Bikle D D; Siiteri P K; Ryzen E; Haddad J G
Serum protein binding of 1,25-dihydroxyvitamin D: a reevaluation by direct measurement of free metabolite levels.
The Journal of clinical endocrinology and metabolism 1985;61(5):969-75.
1984: Bikle D D; Gee E; Halloran B; Haddad J G
Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease.
The Journal of clinical investigation 1984;74(6):1966-71.
1984: Globus R K; Bikle D D; Morey-Holton E
Effects of simulated weightlessness on bone mineral metabolism.
Endocrinology 1984;114(6):2264-70.

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