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Michael Rosenfeld

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Francesca Telese; Dorota Skowronska-Krawczyk; Amir Gamliel; Ivan Garcia-Bassets; Michael G Rosenfeld
"Seq-ing" insights into the epigenetics of neuronal gene regulation.
QiDong Hu; Wenbo Li; Kenneth A Ohgi; David W Rose; Bogdan Tanasa; Michele Trabucchi; Jie Zhang; Christopher K Glass; Michael G Rosenfeld
DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation.
Joshua D Stender; Michael Boutros; Kevin Do; Minna U Kaikkonen; Wen Liu; Gabriel Pascual; Norbert Perrimon; Michael G Rosenfeld; Nathanael J Spann; Christopher K Glass
Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.

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All Publications

2013: Francesca Telese; Dorota Skowronska-Krawczyk; Amir Gamliel; Ivan Garcia-Bassets; Michael G Rosenfeld
"Seq-ing" insights into the epigenetics of neuronal gene regulation.
Neuron 2013;77(4):606-23.
2012: QiDong Hu; Wenbo Li; Kenneth A Ohgi; David W Rose; Bogdan Tanasa; Michele Trabucchi; Jie Zhang; Christopher K Glass; Michael G Rosenfeld
DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation.
Nature structural & molecular biology 2012;19(11):1168-75.
2012: Joshua D Stender; Michael Boutros; Kevin Do; Minna U Kaikkonen; Wen Liu; Gabriel Pascual; Norbert Perrimon; Michael G Rosenfeld; Nathanael J Spann; Christopher K Glass
Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20.
Molecular cell 2012;48(1):28-38.
2012: Zhihong Zhou; Joseph A Adams; Gourisanker Ghosh; Qidong Hu; Hairi Li; Wen Liu; Ryan M Plocinik; Jinsong Qiu; Michael G Rosenfeld; Yu Zhou; Xiang-Dong Fu
The Akt-SRPK-SR axis constitutes a major pathway in transducing EGF signaling to regulate alternative splicing in the nucleus.
Molecular cell 2012;47(3):422-33.
2012: M Dafne Cardamone; Christopher K Glass; Anna Krones; Kenneth A Ohgi; Laura Ricci; Michael G Rosenfeld; Bogdan Tanasa; Havilah Taylor; Valentina Perissi
A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2.
Molecular cell 2012;46(1):91-104.
2012: Hairi Li; Xiangqiang Li; Jinsong Qiu; Michael G Rosenfeld; Dong Wang; Hongyan Zhou; Yu Zhou; Sheng Ding; Xiang-Dong Fu
Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(12):4609-14.
2012: Qidong Hu; Michael G Rosenfeld
Epigenetic regulation of human embryonic stem cells.
Frontiers in genetics 2012;3():238.
2012: Chunru Lin; Liuqing Yang; Michael G Rosenfeld
Molecular logic underlying chromosomal translocations, random or non-random?
Advances in cancer research 2012;113():241-79.
2011: Liuqing Yang; Jie Zhang; Pieter dorrestein; Jonathan D Grinstein; Chunru Lin; Wen Liu; Kenneth A Ohgi; Michael G Rosenfeld
ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs.
Cell 2011;147(4):773-88.
2011: Tamar R Grossman; Kristen Jepsen; julie R korenberg; Karen Ocorr; Kirk L Peterson; Michael G Rosenfeld; Ouarda Taghli-Lamallem; Robert J Wessells; Rolf Bodmer; Amir Gamliel; Ethan Bier
Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects.
PLoS genetics 2011;7(11):e1002344.
2011: Jianrong Wang; Bogdan Pasaniuc; Michael G Rosenfeld; Goli Shariat; Michelle Atallah; Benjamin Blackwell; Peter J Cook; Marek Dobke; Glenn J Geesman; Eran Halperin; Sirkka Liisa Hostikka; I King Jordan; Elbert Lee; Victoria Lunyak
Inhibition of activated pericentromeric SINE/Alu repeat transcription in senescent human adult stem cells reinstates self-renewal.
Cell cycle (Georgetown, Tex.) 2011;10(17):3016-30.
2011: Dong Wang; Yiming Zhou; Chris Benner; Ivan Garcia-Bassets; Christopher K Glass; Minna U Kaikkonen; Wenbo Li; Wen Liu; Kenneth A Ohgi; Jinsong Qiu; Michael G Rosenfeld; Xue Su; Xiang-Dong Fu
Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA.
Nature 2011;474(7351):390-4.
2011: Janusz Puc; Michael G Rosenfeld
SOX2 and CHD7 cooperatively regulate human disease genes.
Nature genetics 2011;43(6):505-6.
2011: Todd S Macfarlan; Wesley D Gifford; Saurabh Agarwal; Shawn Driscoll; Karen Lettieri; Jianxun Wang; Shane E Andrews; Laura Franco; Michael G Rosenfeld; Bing Ren; Samuel L Pfaff
Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A.
Genes & development 2011;25(6):594-607.
2011: Wendy Huang; Serena Ghisletti; Kaoru Saijo; Meghal Gandhi; Myriam Aouadi; Greg J Tesz; Dawn X Zhang; Joyee Yao; Michael P Czech; Bruce L Goode; Michael G Rosenfeld; Christopher K Glass
Coronin 2A mediates actin-dependent de-repression of inflammatory response genes.
Nature 2011;470(7334):414-8.
2011: Olivier Harismendy; Dimple Notani; Xiaoyuan Song; Nazli G Rahim; Bogdan Tanasa; Nathaniel Heintzman; Bing Ren; Xiang-Dong Fu; Eric J Topol; Michael G Rosenfeld; Kelly A Frazer
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response.
Nature 2011;470(7333):264-8.
2011: Xiangting Wang; Xiaoyuan Song; Christopher K Glass; Michael G Rosenfeld
The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs.
Cold Spring Harbor perspectives in biology 2011;3(1):a003756.
2010: Wen Liu; Bogdan Tanasa; Oksana V Tyurina; Tian Yuan Zhou; Reto Gassmann; Wei-Ting Liu; Kenneth A Ohgi; Chris Benner; Ivan Garcia-Bassets; Aneel K Aggarwal; Arshad Desai; Pieter C Dorrestein; Christopher K Glass; Michael G Rosenfeld
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression.
Nature 2010;466(7305):508-12.
2010: Valentina Perissi; Kristen Jepsen; Christopher K Glass; Michael G Rosenfeld
Deconstructing repression: evolving models of co-repressor action.
Nature reviews. Genetics 2010;11(2):109-23.
2010: Michele Trabucchi; Paola Briata; Witold Filipowicz; Andres Ramos; Roberto Gherzi; Michael G Rosenfeld
KSRP promotes the maturation of a group of miRNA precursors.
Advances in experimental medicine and biology 2010;700():36-42.
2009: Chunru Lin; Liuqing Yang; Bogdan Tanasa; Kasey R Hutt; Bong-Gun Ju; Kenneth A Ohgi; Jie Zhang; David W Rose; Xiang-Dong Fu; Christopher K Glass; Michael G Rosenfeld
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer.
Cell 2009;139(6):1069-83.
2009: Michele Trabucchi; Paola Briata; Witold Filipowicz; Michael G Rosenfeld; Andres Ramos; Roberto Gherzi
How to control miRNA maturation?
RNA biology 2009;6(5):536-40.
2009: Esperanza Nunez; Xiang-Dong Fu; Michael G Rosenfeld
Nuclear organization in the 3D space of the nucleus - cause or consequence?
Current opinion in genetics & development 2009;19(5):424-36.
2009: Wendy Huang; Serena Ghisletti; Valentina Perissi; Michael G Rosenfeld; Christopher K Glass
Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint.
Molecular cell 2009;35(1):48-57.
2009: Xiang-Yang Zhong; Pingping Wang; Joonhee Han; Michael G Rosenfeld; Xiang-Dong Fu
SR proteins in vertical integration of gene expression from transcription to RNA processing to translation.
Molecular cell 2009;35(1):1-10.
2009: Michele Trabucchi; Paola Briata; Mariaflor Garcia-Mayoral; Astrid D Haase; Witold Filipowicz; Andres Ramos; Roberto Gherzi; Michael G Rosenfeld
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs.
Nature 2009;459(7249):1010-4.
2009: Maria Dafne Cardamone; Chiara Bardella; Arantxa Gutierrez; Luciano Di Croce; Michael G Rosenfeld; Maria Flavia Di Renzo; Michele De Bortoli
ERalpha as ligand-independent activator of CDH-1 regulates determination and maintenance of epithelial morphology in breast cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(18):7420-5.
2009: Kaoru Saijo; Beate Winner; Christian T Carson; Jana G Collier; Leah Boyer; Michael G Rosenfeld; Fred H Gage; Christopher K Glass
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death.
Cell 2009;137(1):47-59.
2009: Peter J Cook; Bong-Gun Ju; Francesca Telese; Xiangting Wang; Christopher K Glass; Michael G Rosenfeld
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.
Nature 2009;458(7238):591-6.
2009: Serena Ghisletti; Wendy Huang; Kristen Jepsen; Chris Benner; Gary Hardiman; Michael G Rosenfeld; Christopher K Glass
Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways.
Genes & development 2009;23(6):681-93.
2009: Wenlai Zhou; Xiangting Wang; Michael G Rosenfeld
Histone H2A ubiquitination in transcriptional regulation and DNA damage repair.
The international journal of biochemistry & cell biology 2009;41(1):12-5.
2008: Juhee Jeong; Xue Li; Robert J McEvilly; Michael G Rosenfeld; Thomas Lufkin; John L R Rubenstein
Dlx genes pattern mammalian jaw primordium by regulating both lower jaw-specific and upper jaw-specific genetic programs.
Development (Cambridge, England) 2008;135(17):2905-16.
2008: Esperanza Nunez; Young-Soo Kwon; Kasey R Hutt; Qidong Hu; Maria Dafne Cardamone; Kenneth A Ohgi; Ivan Garcia-Bassets; David W Rose; Christopher K Glass; Michael G Rosenfeld; Xiang-Dong Fu
Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules.
Cell 2008;134(1):189.
2008: Anatoli Gleiberman; Tatyana Michurina; Juan Manuel Encinas; Jose L Roig; Peter Krasnov; Francesca Balordi; Gord Fishell; Michael G Rosenfeld; Grigori Enikolopov
Genetic approaches identify adult pituitary stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(17):6332-7.
2008: Valentina Perissi; Claudio Scafoglio; Jie Zhang; Kenneth A Ohgi; David W Rose; Christopher K Glass; Michael G Rosenfeld
TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints.
Molecular cell 2008;29(6):755-66.
2008: Esperanza Nunez; Young-Soo Kwon; Kasey R Hutt; Qidong Hu; Maria Dafne Cardamone; Kenneth A Ohgi; Ivan Garcia-Bassets; David W Rose; Christopher K Glass; Michael G Rosenfeld; Xiang-Dong Fu
Nuclear receptor-enhanced transcription requires motor- and LSD1-dependent gene networking in interchromatin granules.
Cell 2008;132(6):996-1010.
2008: Kristen Jepsen; Anatoli Gleiberman; Can Shi; Daniel I Simon; Michael G Rosenfeld
Cooperative regulation in development by SMRT and FOXP1.
Genes & development 2008;22(6):740-5.
2008: Yingchuan Qi; Jeffrey A Ranish; Xiaoyan Zhu; Anna Krones; Jie Zhang; Ruedi Aebersold; David W Rose; Michael G Rosenfeld; C Carrière
Atbf1 is required for the Pit1 gene early activation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2481-6.
2008: Wenlai Zhou; Ping Zhu; Jianxun Wang; Gabriel Pascual; Kenneth A Ohgi; Jean Lozach; Christopher K Glass; Michael G Rosenfeld
Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation.
Molecular cell 2008;29(1):69-80.
2007: Xiaoyan Zhu; Jianxun Wang; Bong-Gun Ju; Michael G Rosenfeld
Signaling and epigenetic regulation of pituitary development.
Current opinion in cell biology 2007;19(6):605-11.
2007: Kristen Jepsen; Derek Solum; Tianyuan Zhou; Robert J McEvilly; Hyun-Jung Kim; Christopher K Glass; Ola Hermanson; Michael G Rosenfeld
SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron.
Nature 2007;450(7168):415-9.
2007: Wenlai Zhou; Lizhu Lin; Arindam Majumdar; Xue Li; Xiaoxue Zhang; Wei Liu; Leah Etheridge; Yunqing Shi; James Martin; Wim Van de Ven; Vesa Kaartinen; Anthony Wynshaw-Boris; Andrew P McMahon; Michael G Rosenfeld; Sylvia M Evans
Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2.
Nature genetics 2007;39(10):1225-34.
2007: Ping Zhu; Wenlai Zhou; Jianxun Wang; Janusz Puc; Kenneth A Ohgi; Hediye Erdjument-Bromage; Paul Tempst; Christopher K Glass; Michael G Rosenfeld
A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation.
Molecular cell 2007;27(4):609-21.
2007: Victoria Lunyak; Gratien Prefontaine; Esperanza Núñez; Thorsten Cramer; Bong-Gun Ju; Kenneth A Ohgi; Kasey R Hutt; Rosa Roy; Angel García-Díaz; Xiaoyan Zhu; Yun Yung; Lluis Montoliu; Christopher K Glass; Michael G Rosenfeld
Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis.
Science (New York, N.Y.) 2007;317(5835):248-51.
2007: Xiaoyan Zhu; Anatoli Gleiberman; Michael G Rosenfeld
Molecular physiology of pituitary development: signaling and transcriptional networks.
Physiological reviews 2007;87(3):933-63.
2007: Lizhu Lin; Li Cui; Wenlai Zhou; Daniel Dufort; Xiaoxue Zhang; Chen-Leng Cai; Lei Bu; Lei Yang; Jody Martin; Rolf Kemler; Michael G Rosenfeld; Ju Chen; Sylvia M Evans
Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(22):9313-8.
2007: Jianxun Wang; Kathleen Scully; Xiaoyan Zhu; Ling Cai; Jie Zhang; Gratien Prefontaine; Anna Krones; Kenneth A Ohgi; Ping Zhu; Ivan Garcia-Bassets; Forrest Liu; Havilah Taylor; Jean Lozach; Friederike L Jayes; Kenneth S Korach; Christopher K Glass; Xiang-Dong Fu; Michael G Rosenfeld
Opposing LSD1 complexes function in developmental gene activation and repression programmes.
Nature 2007;446(7138):882-7.
2007: Young-Soo Kwon; Ivan Garcia-Bassets; Kasey R Hutt; Christine S Cheng; Mingjie Jin; Dongyan Liu; Chris Benner; Dong Wang; Zhen Ye; Marina Bibikova; Jian-Bing Fan; Lingxun Duan; Christopher K Glass; Michael G Rosenfeld; Xiang-Dong Fu
Sensitive ChIP-DSL technology reveals an extensive estrogen receptor alpha-binding program on human gene promoters.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(12):4852-7.
2007: Ivan Garcia-Bassets; Young-Soo Kwon; Francesca Telese; Gratien Prefontaine; Kasey R Hutt; Christine S Cheng; Bong-Gun Ju; Kenneth A Ohgi; Jianxun Wang; Laure Escoubet-Lozach; David W Rose; Christopher K Glass; Xiang-Dong Fu; Michael G Rosenfeld
Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors.
Cell 2007;128(3):505-18.
2007: Serena Ghisletti; Wendy Huang; Sumito Ogawa; Gabriel Pascual; Mu-En Lin; Timothy M Willson; Michael G Rosenfeld; Christopher K Glass
Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma.
Molecular cell 2007;25(1):57-70.
2007: Gabriel Pascual; Amy L Sullivan; Sumito Ogawa; Amir Gamliel; Valentina Perissi; Michael G Rosenfeld; Christopher K Glass
Anti-inflammatory and antidiabetic roles of PPARgamma.
Novartis Foundation symposium 2007;286():183-96; discussion 196-203.
2006: Bong-Gun Ju; Michael G Rosenfeld
A breaking strategy for topoisomerase IIbeta/PARP-1-dependent regulated transcription.
Cell cycle (Georgetown, Tex.) 2006;5(22):2557-60.
2006: Kevin T Bush; Duke A Vaughn; Xue Li; Michael G Rosenfeld; David W Rose; Stanley A Mendoza; Sanjay K Nigam
Development and differentiation of the ureteric bud into the ureter in the absence of a kidney collecting system.
Developmental biology 2006;298(2):571-84.
2006: Xiaoyan Zhu; Jie Zhang; Jessica Tollkuhn; Ryosuke Ohsawa; Emery H Bresnick; François Guillemot; Ryoichiro Kageyama; Michael G Rosenfeld
Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis.
Genes & development 2006;20(19):2739-53.
2006: Bong-Gun Ju; Victoria Lunyak; Valentina Perissi; Ivan Garcia-Bassets; David W Rose; Christopher K Glass; Michael G Rosenfeld
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.
Science (New York, N.Y.) 2006;312(5781):1798-802.
2006: Michael G Rosenfeld; Victoria Lunyak; Christopher K Glass
Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response.
Genes & development 2006;20(11):1405-28.
2006: Kazuhito Toyo-Oka; Timothy Bowen; Shinji Hirotsune; Zirong Li; Sonia Jain; Sara Ota; Laure Escoubet-Lozach; Laure Escoubet Lozach; Ivan Garcia-Bassets; Ivan Garcia Bassett; Jean Lozach; Michael G Rosenfeld; Christopher K Glass; Robert N Eisenman; Bing Ren; Peter J Hurlin; Anthony Wynshaw-Boris
Mnt-deficient mammary glands exhibit impaired involution and tumors with characteristics of myc overexpression.
Cancer research 2006;66(11):5565-73.
2006: Lorin E. Olson; Jessica Tollkuhn; Claudio Scafoglio; Anna Krones; Jie Zhang; Kenneth A Ohgi; Wei Wu; Makoto M Taketo; Rolf Kemler; Rudolf Grosschedl; Dave Rose; Xue Li; Michael G Rosenfeld
Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination.
Cell 2006;125(3):593-605.
2006: Ping Zhu; Sung Hee Baek; Eliot M Bourk; Kenneth A Ohgi; Ivan Garcia-Bassets; Hideki Sanjo; Shizuo Akira; Paul F Kotol; Christopher K Glass; Michael G Rosenfeld; David W Rose
Macrophage/cancer cell interactions mediate hormone resistance by a nuclear receptor derepression pathway.
Cell 2006;124(3):615-29.
2005: Anatoli Gleiberman; Juan Manuel Encinas; John L Mignone; Tatyana Michurina; Michael G Rosenfeld; Grigori Enikolopov
Expression of nestin-green fluorescent protein transgene marks oval cells in the adult liver.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;234(2):413-21.
2005: Gabriel Pascual; Amy L Fong; Sumito Ogawa; Amir Gamliel; Andrew C Li; Valentina Perissi; David W Rose; Timothy M Willson; Michael G Rosenfeld; Christopher K Glass
A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.
Nature 2005;437(7059):759-63.
2005: Sumito Ogawa; Jean Lozach; Chris Benner; Gabriel Pascual; Rajendra K Tangirala; Stefan Westin; Alexander Hoffmann; Shankar Subramaniam; Michael David; Michael G Rosenfeld; Christopher K Glass
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.
Cell 2005;122(5):707-21.
2005: Valentina Perissi; Michael G Rosenfeld
Controlling nuclear receptors: the circular logic of cofactor cycles.
Nature reviews. Molecular cell biology 2005;6(7):542-54.
2005: Xiaoyan Zhu; Chijen Lin; Gratien Prefontaine; Jessica Tollkuhn; Michael G Rosenfeld
Genetic control of pituitary development and hypopituitarism.
Current opinion in genetics & development 2005;15(3):332-40.
2005: Tae Hoon Kim; Leah O Barrera; Chunxu Qu; Sara Van Calcar; Nathan D Trinklein; Sara J Cooper; Rosa M Luna; Christopher K Glass; Michael G Rosenfeld; Richard Myers; Bing Ren
Direct isolation and identification of promoters in the human genome.
Genome research 2005;15(6):830-9.
2005: Victoria Lunyak; Michael G Rosenfeld
No rest for REST: REST/NRSF regulation of neurogenesis.
Cell 2005;121(4):499-501.
2005: Chen-Leng Cai; Wenlai Zhou; Lei Yang; Lei Bu; Yibing Qyang; Xiaoxue Zhang; Xiaodong Li; Michael G Rosenfeld; Ju Chen; Sylvia Evans
T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis.
Development (Cambridge, England) 2005;132(10):2475-87.
2005: Lorin E. Olson; Jie Zhang; Havilah Taylor; David Rose; Michael G Rosenfeld
Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(10):3708-13.
2005: Xiangdong Xu; Dongmei Yang; Jian-Hua Ding; Wang Wang; Pao-Hsien Chu; Nancy Dalton; Huan-You Wang; Jamie Pennington; Zhen Ye; Forrest Liu; Michael G Rosenfeld; James L Manley; John Ross; Ju Chen; Rui-Ping Xiao; Heping Cheng; Xiang-Dong Fu
ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle.
Cell 2005;120(1):59-72.
2005: Francesca Telese; Paola Bruni; Aldo Donizetti; Davide Gianni; Chiara D'Ambrosio; Andrea Scaloni; Nicola Zambrano; Michael G Rosenfeld; Tommaso Russo
Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET.
EMBO reports 2005;6(1):77-82.
2004: Timothy V Beischlag; Robert T Taylor; David W Rose; Diana Yoon; Yumay Chen; Wen-Hwa Lee; Michael G Rosenfeld; Oliver Hankinson
Recruitment of thyroid hormone receptor/retinoblastoma-interacting protein 230 by the aryl hydrocarbon receptor nuclear translocator is required for the transcriptional response to both dioxin and hypoxia.
The Journal of biological chemistry 2004;279(52):54620-8.
2004: Bong-Gun Ju; Derek Solum; Eun Joo Song; Kong-Joo Lee; David W Rose; Christopher K Glass; Michael G Rosenfeld
Activating the PARP-1 sensor component of the groucho/ TLE1 corepressor complex mediates a CaMKinase IIdelta-dependent neurogenic gene activation pathway.
Cell 2004;119(6):815-29.
2004: Sumito Ogawa; Jean Lozach; Kristen Jepsen; Dominique Sawka-Verhelle; Valentina Perissi; Roman Sasik; David W Rose; Randall S Johnson; Michael G Rosenfeld; Christopher K Glass
A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(40):14461-6.
2004: Xiaoyan Zhu; Michael G Rosenfeld
Transcriptional control of precursor proliferation in the early phases of pituitary development.
Current opinion in genetics & development 2004;14(5):567-74.
2004: Edward Korzus; Michael G Rosenfeld; Mark Mayford
CBP histone acetyltransferase activity is a critical component of memory consolidation.
Neuron 2004;42(6):961-72.
2004: Kazuhito Toyo-Oka; Shinji Hirotsune; Michael J Gambello; Zi-Qiang Zhou; Lorin E. Olson; Michael G Rosenfeld; Robert N Eisenman; Peter J Hurlin; Anthony Wynshaw-Boris
Loss of the Max-interacting protein Mnt in mice results in decreased viability, defective embryonic growth and craniofacial defects: relevance to Miller-Dieker syndrome.
Human molecular genetics 2004;13(10):1057-67.
2004: Victoria Lunyak; Gratien Prefontaine; Michael G Rosenfeld
REST and peace for the neuronal-specific transcriptional program.
Annals of the New York Academy of Sciences 2004;1014():110-20.
2004: Catherine Carrière; Anatoli Gleiberman; Chijen Lin; Michael G Rosenfeld
From panhypopituitarism to combined pituitary deficiencies: do we need the anterior pituitary?
Reviews in endocrine & metabolic disorders 2004;5(1):5-13.
2004: Valentina Perissi; Aneel Aggarwal; Christopher K Glass; David W Rose; Michael G Rosenfeld
A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.
Cell 2004;116(4):511-26.
2004: Charlie D Chen; Derek S Welsbie; Chris Tran; Sung Hee Baek; Randy Chen; Robert L Vessella; Michael G Rosenfeld; Charles L Sawyers
Molecular determinants of resistance to antiandrogen therapy.
Nature medicine 2004;10(1):33-9.
2003: David A Gold; Sung Hee Baek; Nicholas J Schork; David W Rose; DeLaine D Larsen; Benjamin D Sachs; Michael G Rosenfeld; Bruce A Hamilton
RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways.
Neuron 2003;40(6):1119-31.
2003: Xue Li; Kenneth A Oghi; Jie Zhang; Anna Krones; Kevin T Bush; Christopher K Glass; Sanjay K Nigam; Aneel K Aggarwal; Richard Maas; David W Rose; Michael G Rosenfeld
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.
Nature 2003;426(6964):247-54.
2003: Paola Briata; Cristina Ilengo; Giorgio Corte; Christoph Moroni; Michael G Rosenfeld; Ching-Yi Chen; Roberto Gherzi
The Wnt/beta-catenin-->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs.
Molecular cell 2003;12(5):1201-11.
2003: Sung Hee Baek; Chrissa Kioussi; Paola Briata; Degeng Wang; H D Nguyen; Kenneth A Ohgi; Christopher K Glass; Anthony Wynshaw-Boris; David W Rose; Michael G Rosenfeld
Regulated subset of G1 growth-control genes in response to derepression by the Wnt pathway.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3245-50.
2003: Lorin E. Olson; Jeremy S Dasen; Bong-Gun Ju; Jessica Tollkuhn; Michael G Rosenfeld
Paired-like repression/activation in pituitary development.
Recent progress in hormone research 2003;58():249-61.
2002: Jamie Pennington; Susan Shumas; Tom Whisenhunt; Erich Sirkowski; Shawn O'Connell; Steven S Scherer; Michael G Rosenfeld
Identification of genes that are downregulated in the absence of the POU domain transcription factor pou3f1 (Oct-6, Tst-1, SCIP) in sciatic nerve.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(23):10217-31.
2002: Victoria Lunyak; Robert Burgess; Gratien Prefontaine; Charles Nelson; Sing-Hoi Sze; Josh Chenoweth; Phillip Schwartz; Pavel A Pevzner; Christopher Glass; Gail Mandel; Michael G Rosenfeld
Corepressor-dependent silencing of chromosomal regions encoding neuronal genes.
Science (New York, N.Y.) 2002;298(5599):1747-52.
2002: Chrissa Kioussi; Paola Briata; Sung Hee Baek; David W Rose; Natasha S Hamblet; Thomas Herman; Kenneth A Ohgi; Chijen Lin; Anatoli Gleiberman; Jianbo Wang; Véronique Brault; Pilar Ruiz-Lozano; H D Nguyen; Rolf Kemler; Christopher K Glass; Anthony Wynshaw-Boris; Michael G Rosenfeld
Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development.
Cell 2002;111(5):673-85.
2002: Ola Hermanson; Kristen Jepsen; Michael G Rosenfeld
N-CoR controls differentiation of neural stem cells into astrocytes.
Nature 2002;419(6910):934-9.
2002: Elena Battaglioli; Maria E Andrés; David W Rose; Josh Chenoweth; Michael G Rosenfeld; Mary E Anderson; Gail Mandel
REST repression of neuronal genes requires components of the hSWI.SNF complex.
The Journal of biological chemistry 2002;277(43):41038-45.
2002: Vivek Kumar; Justin E Carlson; Kenneth A Ohgi; Thomas A Edwards; David W Rose; Carlos R Escalante; Michael G Rosenfeld; Aneel K Aggarwal
Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase.
Molecular cell 2002;10(4):857-69.
2002: Xue Li; Valentina Perissi; Forrest Liu; David W Rose; Michael G Rosenfeld
Tissue-specific regulation of retinal and pituitary precursor cell proliferation.
Science (New York, N.Y.) 2002;297(5584):1180-3.
2002: Sung Hee Baek; Kenneth A Ohgi; David W Rose; Edward H Koo; Christopher K Glass; Michael G Rosenfeld
Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein.
Cell 2002;110(1):55-67.
2002: Timothy V Beischlag; Song Wang; David W Rose; Joseph Torchia; Suzanne Reisz-Porszasz; Khurshid Muhammad; Walter E Nelson; Markus R Probst; Michael G Rosenfeld; Oliver Hankinson
Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex.
Molecular and cellular biology 2002;22(12):4319-33.
2002: Lorin E. Olson; Michael G Rosenfeld
Perspective: genetic and genomic approaches in elucidating mechanisms of pituitary development.
Endocrinology 2002;143(6):2007-11.
2002: Günter W Klappacher; Victoria Lunyak; David B Sykes; Dominique Sawka-Verhelle; Julien Sage; Gyan Brard; Sally D Ngo; Denise Gangadharan; Tyler Jacks; Mark P Kamps; David W Rose; Michael G Rosenfeld; Christopher K Glass
An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation.
Cell 2002;109(2):169-80.
2002: Kathleen M Scully; Michael G Rosenfeld
Pituitary development: regulatory codes in mammalian organogenesis.
Science (New York, N.Y.) 2002;295(5563):2231-5.
2002: Ola Hermanson; Christopher K Glass; Michael G Rosenfeld
Nuclear receptor coregulators: multiple modes of modification.
Trends in endocrinology and metabolism: TEM 2002;13(2):55-60.
2002: Robert J McEvilly; Marcela Ortiz de Diaz; Marcus D Schonemann; Farideh Hooshmand; Michael G Rosenfeld
Transcriptional regulation of cortical neuron migration by POU domain factors.
Science (New York, N.Y.) 2002;295(5559):1528-32.
2002: Kristen Jepsen; Michael G Rosenfeld
Biological roles and mechanistic actions of co-repressor complexes.
Journal of cell science 2002;115(Pt 4):689-98.
2002: Chrissa Kioussi; Paola Briata; Sung Hee Baek; Anthony Wynshaw-Boris; David W Rose; Michael G Rosenfeld
Pitx genes during cardiovascular development.
Cold Spring Harbor symposia on quantitative biology 2002;67():81-7.
2001: Jeremy S Dasen; T S Herman; S O Connell; Lorin E. Olson; Bong-Gun Ju; Jessica Tollkuhn; S H Baek; David W Rose; J P Martinez Barbera; Michael G Rosenfeld
Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis.
Genes & development 2001;15(23):3193-207.
2001: Michael G Rosenfeld; Christopher K Glass
Coregulator codes of transcriptional regulation by nuclear receptors.
The Journal of biological chemistry 2001;276(40):36865-8.
2001: Nurit Ballas; Elena Battaglioli; F Atouf; M E Andres; Josh Chenoweth; M E Anderson; C Burger; Mariko Moniwa; James Davie; William J Bowers; Howard Federoff; David W Rose; Michael G Rosenfeld; Paul Brehm; Gail Mandel
Regulation of neuronal traits by a novel transcriptional complex.
Neuron 2001;31(3):353-65.
2001: J Liu; C Lin; Anatoli Gleiberman; Kenneth A Ohgi; Thomas Herman; H P Huang; M J Tsai; Michael G Rosenfeld
Tbx19, a tissue-selective regulator of POMC gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8674-9.
2001: T Murata; R Kurokawa; Anna Krones; K Tatsumi; M Ishii; Tomohiko Taki; M Masuno; H Ohashi; M Yanagisawa; Michael G Rosenfeld; Christopher K Glass; Yasuhide Hayashi
Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome.
Human molecular genetics 2001;10(10):1071-6.
2001: Jamie Pennington; Susan Shumas; Tom Whisenhunt; Michael G Rosenfeld; Steven S Scherer
Modification of representational difference analysis applied to the isolation of forskolin-regulated genes from Schwann cells.
Journal of neuroscience research 2001;63(6):516-24.
2001: M Treier; SM O'Connell; Anatoli Gleiberman; J Price; DP Szeto; R Burgess; P T Chuang; Andrew P McMahon; Michael G Rosenfeld
Hedgehog signaling is required for pituitary gland development.
Development (Cambridge, England) 2001;128(3):377-86.
2001: Jeremy S Dasen; Michael G Rosenfeld
Signaling and transcriptional mechanisms in pituitary development.
Annual review of neuroscience 2001;24():327-55.
2000: Z Wang; David W Rose; Ola Hermanson; F Liu; Thomas Herman; W Wu; DP Szeto; Anatoli Gleiberman; Anna Krones; K Pratt; Ronald G Rosenfeld; Christopher K Glass; Michael G Rosenfeld
Regulation of somatic growth by the p160 coactivator p/CIP.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(25):13549-54.
2000: L Erkman; Paul Yates; Todd McLaughlin; Robert J McEvilly; Tom Whisenhunt; S M O'Connell; Anna Krones; M A Kirby; David H Rapaport; Jamie Pennington; Dennis D M O'Leary; Michael G Rosenfeld
A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system.
Neuron 2000;28(3):779-92.
2000: Kathleen M Scully; Eric M Jacobson; Kristen Jepsen; Victoria Lunyak; Hector Viadiu; C Carrière; David W Rose; Farideh Hooshmand; Aneel K Aggarwal; Michael G Rosenfeld
Allosteric effects of Pit-1 DNA sites on long-term repression in cell type specification.
Science (New York, N.Y.) 2000;290(5494):1127-31.
2000: Kristen Jepsen; Ola Hermanson; Thandi M Onami; Anatoli Gleiberman; Victoria Lunyak; Robert J McEvilly; R Kurokawa; V Kumar; Forrest Liu; E Seto; Stephen M Hedrick; Gail Mandel; Christopher K Glass; David W Rose; Michael G Rosenfeld
Combinatorial roles of the nuclear receptor corepressor in transcription and development.
Cell 2000;102(6):753-63.
2000: Yu-Der Wen; Valentina Perissi; L M Staszewski; Wen-Ming Yang; Anna Krones; Christopher K Glass; Michael G Rosenfeld; E Seto
The histone deacetylase-3 complex contains nuclear receptor corepressors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7202-7.
2000: Juan Llopis; S Westin; Mercedes Ricote; Zuncai Wang; C Y Cho; R Kurokawa; TM Mullen; David W Rose; Michael G Rosenfeld; Roger Y Tsien; Christopher K Glass; J Wang
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):4363-8.
2000: T Kishimoto; Jelena Radulovic; Marko Radulovic; Chijen Lin; Christina Schrick; Farideh Hooshmand; Ola Hermanson; Michael G Rosenfeld; Joachim Spiess
Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2.
Nature genetics 2000;24(4):415-9.
2000: Christopher K Glass; Michael G Rosenfeld
The coregulator exchange in transcriptional functions of nuclear receptors.
Genes & development 2000;14(2):121-41.
2000: Michael G Rosenfeld; Paola Briata; Jeremy S Dasen; Anatoli Gleiberman; Chrissa Kioussi; C Lin; SM O'Connell; A Ryan; DP Szeto; M Treier
Multistep signaling and transcriptional requirements for pituitary organogenesis in vivo.
Recent progress in hormone research 2000;55():1-13; discussion 13-4.
2000: S Westin; Michael G Rosenfeld; Christopher K Glass
Nuclear receptor coactivators.
Advances in pharmacology (San Diego, Calif.) 2000;47():89-112.
1999: Valentina Perissi; L M Staszewski; EM McInerney; R Kurokawa; Anna Krones; David W Rose; Millard H Lambert; MV Milburn; Christopher K Glass; Michael G Rosenfeld
Molecular determinants of nuclear receptor-corepressor interaction.
Genes & development 1999;13(24):3198-208.
1999: Chrissa Kioussi; SM O'Connell; L St-Onge; M Treier; Anatoli Gleiberman; P Gruss; Michael G Rosenfeld
Pax6 is essential for establishing ventral-dorsal cell boundaries in pituitary gland development.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14378-82.
1999: Jeremy S Dasen; Michael G Rosenfeld
Signaling mechanisms in pituitary morphogenesis and cell fate determination.
Current opinion in cell biology 1999;11(6):669-77.
1999: Chijen Lin; Chrissa Kioussi; SM O'Connell; Paola Briata; DP Szeto; Forrest Liu; Juan Carlos Izpisúa Belmonte; Michael G Rosenfeld
Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis.
Nature 1999;401(6750):279-82.
1999: A S Gleiberman; N G Fedtsova; Michael G Rosenfeld
Tissue interactions in the induction of anterior pituitary: role of the ventral diencephalon, mesenchyme, and notochord.
Developmental biology 1999;213(2):340-53.
1999: K A Sheppard; David W Rose; Z K Haque; R Kurokawa; EM McInerney; S Westin; D Thanos; Michael G Rosenfeld; Christopher K Glass; T Collins
Transcriptional activation by NF-kappaB requires multiple coactivators.
Molecular and cellular biology 1999;19(9):6367-78.
1999: Ingolf Bach; Concepcion Rodriguez-Esteban; C Carrière; A Bhushan; Anna Krones; David W Rose; Christopher K Glass; Bogi Andersen; Juan Carlos Izpisúa Belmonte; Michael G Rosenfeld
RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex.
Nature genetics 1999;22(4):394-9.
1999: C Kioussi; Michael G Rosenfeld
Body's left side.
Cellular and molecular biology (Noisy-le-Grand, France) 1999;45(5):517-22.
1999: Jeremy S Dasen; SM O'Connell; SE Flynn; M Treier; Anatoli Gleiberman; DP Szeto; Farideh Hooshmand; Aneel K Aggarwal; Michael G Rosenfeld
Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types.
Cell 1999;97(5):587-98.
1999: L Xu; C K Glass; Michael G Rosenfeld
Coactivator and corepressor complexes in nuclear receptor function.
Current opinion in genetics & development 1999;9(2):140-7.
1999: Valentina Perissi; Jeremy S Dasen; R Kurokawa; Zuncai Wang; Edward Korzus; David W Rose; Christopher K Glass; Michael G Rosenfeld
Factor-specific modulation of CREB-binding protein acetyltransferase activity.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3652-7.
1999: DP Szeto; Concepcion Rodriguez-Esteban; Aimee Ryan; SM O'Connell; Forrest Liu; Chrissa Kioussi; Anatoli Gleiberman; Juan Carlos Izpisúa Belmonte; Michael G Rosenfeld
Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development.
Genes & development 1999;13(4):484-94.
1999: Robert J McEvilly; Michael G Rosenfeld
The role of POU domain proteins in the regulation of mammalian pituitary and nervous system development.
Progress in nucleic acid research and molecular biology 1999;63():223-55.
1999: M W Sornson; Michael G Rosenfeld
Genetically directed representational difference analysis-based positional cloning and snorthern analysis of candidate genes.
Methods in enzymology 1999;306():67-89.
1998: Bart Lutterbach; JJ Westendorf; Bryan Linggi; A Patten; Mariko Moniwa; James Davie; K D Huynh; Vivian J Bardwell; RM Lavinsky; Michael G Rosenfeld; C Glass; Edward Seto; Scott W Hiebert
ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors.
Molecular and cellular biology 1998;18(12):7176-84.
1998: K A Sheppard; K M Phelps; A J Williams; D Thanos; Christopher K Glass; Michael G Rosenfeld; M E Gerritsen; T Collins
Nuclear integration of glucocorticoid receptor and nuclear factor-kappaB signaling by CREB-binding protein and steroid receptor coactivator-1.
The Journal of biological chemistry 1998;273(45):29291-4.
1998: EM McInerney; David W Rose; SE Flynn; S Westin; TM Mullen; Anna Krones; J Inostroza; Joseph Torchia; Robert T Nolte; N Assa-Munt; MV Milburn; Christopher K Glass; Michael G Rosenfeld
Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation.
Genes & development 1998;12(21):3357-68.
1998: Edgardo J Arroyo; Jamie Pennington; Michael G Rosenfeld; Steven S Scherer
Promyelinating Schwann cells express Tst-1/SCIP/Oct-6.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(19):7891-902.
1998: Li Xu; RM Lavinsky; Jeremy S Dasen; SE Flynn; EM McInerney; TM Mullen; T Heinzel; DP Szeto; Edward Korzus; R Kurokawa; Aneel K Aggarwal; David W Rose; Christopher K Glass; Michael G Rosenfeld
Signal-specific co-activator domain requirements for Pit-1 activation.
Nature 1998;395(6699):301-6.
1998: S Westin; R Kurokawa; Robert T Nolte; G Bruce Wisely; EM McInerney; David W Rose; MV Milburn; Michael G Rosenfeld; Christopher K Glass
Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators.
Nature 1998;395(6698):199-202.
1998: Robert T Nolte; G Bruce Wisely; S Westin; Jeffery Cobb; Millard H Lambert; R Kurokawa; Michael G Rosenfeld; Timothy M Willson; Christopher K Glass; MV Milburn
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.
Nature 1998;395(6698):137-43.
1998: Aimee Ryan; B Blumberg; Concepcion Rodriguez-Esteban; S Yonei-Tamura; K Tamura; T Tsukui; J De La Peña; W Sabbagh; Jason Greenwald; Senyon Choe; Dominic P Norris; Elizabeth J Robertson; Ronald M Evans; Michael G Rosenfeld; Juan Carlos Izpisúa Belmonte
Pitx2 determines left-right asymmetry of internal organs in vertebrates.
Nature 1998;394(6693):545-51.
1998: Carol D Laherty; AN Billin; RM Lavinsky; Gregory S Yochum; A C Bush; J M Sun; TM Mullen; James Davie; David W Rose; Christopher K Glass; Michael G Rosenfeld; Donald E Ayer; Robert N Eisenman
SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors.
Molecular cell 1998;2(1):33-42.
1998: Joseph Torchia; C Glass; Michael G Rosenfeld
Co-activators and co-repressors in the integration of transcriptional responses.
Current opinion in cell biology 1998;10(3):373-83.
1998: M Treier; Anatoli Gleiberman; SM O'Connell; DP Szeto; J A McMahon; Andrew P McMahon; Michael G Rosenfeld
Multistep signaling requirements for pituitary organogenesis in vivo.
Genes & development 1998;12(11):1691-704.
1998: RM Lavinsky; Kristen Jepsen; T Heinzel; Joseph Torchia; TM Mullen; R Schiff; A L Del-Rio; Mercedes Ricote; Sally D Ngo; J Gemsch; S G Hilsenbeck; C Kent Osborne; Christopher K Glass; Michael G Rosenfeld; David W Rose
Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):2920-5.
1998: W Wu; Joy D Cogan; Roland Pfäffle; Jeremy S Dasen; Herwig Frisch; SM O'Connell; SE Flynn; Milton R. Brown; Primus E Mullis; John Parks; John A Phillips; Michael G Rosenfeld
Mutations in PROP1 cause familial combined pituitary hormone deficiency.
Nature genetics 1998;18(2):147-9.
1998: Edward Korzus; Joseph Torchia; David W Rose; Li Xu; R Kurokawa; EM McInerney; TM Mullen; Christopher K Glass; Michael G Rosenfeld
Transcription factor-specific requirements for coactivators and their acetyltransferase functions.
Science (New York, N.Y.) 1998;279(5351):703-7.
1998: R Kurokawa; D Kalafus; MH Ogliastro; Chrissa Kioussi; Li Xu; Joseph Torchia; Michael G Rosenfeld; Christopher K Glass
Differential use of CREB binding protein-coactivator complexes.
Science (New York, N.Y.) 1998;279(5351):700-3.
1998: Marcus D Schonemann; Aimee Ryan; L Erkman; Robert J McEvilly; Jamie Pennington; Michael G Rosenfeld
POU domain factors in neural development.
Advances in experimental medicine and biology 1998;449():39-53.
1997: I Zamir; Jessica P. Dawson; R M Lavinsky; C K Glass; Michael G Rosenfeld; Mitchell Lazar
Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14400-5.
1997: F Hedjran; J M Yeakley; G S Huh; R O Hynes; Michael G Rosenfeld
Control of alternative pre-mRNA splicing by distributed pentameric repeats.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(23):12343-7.
1997: Bogi Andersen; Wendy C Weinberg; O Rennekampff; Robert J McEvilly; John R Bermingham; Farideh Hooshmand; Vyacheslav V Vasilyev; J F Hansbrough; Mark Pittelkow; S H Yuspa; Michael G Rosenfeld
Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation.
Genes & development 1997;11(14):1873-84.
1997: R V Pearse; D W Drolet; K A Kalla; Farideh Hooshmand; John R Bermingham; Michael G Rosenfeld
Reduced fertility in mice deficient for the POU protein sperm-1.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7555-60.
1997: Joseph Torchia; David W Rose; J Inostroza; Y Kamei; S Westin; Christopher K Glass; Michael G Rosenfeld
The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function.
Nature 1997;387(6634):677-84.
1997: Ingolf Bach; C Carrière; Heather P Ostendorff; Bogi Andersen; Michael G Rosenfeld
A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins.
Genes & development 1997;11(11):1370-80.
1997: M Söderström; A Vo; T Heinzel; RM Lavinsky; Wen-Ming Yang; E Seto; D A Peterson; Michael G Rosenfeld; Christopher K Glass
Differential effects of nuclear receptor corepressor (N-CoR) expression levels on retinoic acid receptor-mediated repression support the existence of dynamically regulated corepressor complexes.
Molecular endocrinology (Baltimore, Md.) 1997;11(6):682-92.
1997: Kathleen M Scully; Anatoli Gleiberman; J Lindzey; D B Lubahn; Kenneth S Korach; Michael G Rosenfeld
Role of estrogen receptor-alpha in the anterior pituitary gland.
Molecular endocrinology (Baltimore, Md.) 1997;11(6):674-81.
1997: Aimee Ryan; Michael G Rosenfeld
POU domain family values: flexibility, partnerships, and developmental codes.
Genes & development 1997;11(10):1207-25.
1997: Christopher K Glass; Michael G Rosenfeld; David W Rose; R Kurokawa; Y Kamei; Li Xu; Joseph Torchia; MH Ogliastro; S Westin
Mechanisms of transcriptional activation by retinoic acid receptors.
Biochemical Society transactions 1997;25(2):602-5.
1997: T Heinzel; RM Lavinsky; TM Mullen; M Söderstrom; Carol D Laherty; Joseph Torchia; Wen-Ming Yang; Gyan Brard; Sally D Ngo; James Davie; E Seto; Robert N Eisenman; David W Rose; Christopher K Glass; Michael G Rosenfeld
A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression.
Nature 1997;387(6628):43-8.
1997: J DiRenzo; M Söderstrom; R Kurokawa; MH Ogliastro; Mercedes Ricote; S Ingrey; A Hörlein; Michael G Rosenfeld; Christopher K Glass
Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors.
Molecular and cellular biology 1997;17(4):2166-76.
1997: Patricia A Labosky; GE Winnier; Thomas L Jetton; LK Hargett; Aimee Ryan; Michael G Rosenfeld; A F Parlow; Brigid L M Hogan
The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex.
Development (Cambridge, England) 1997;124(7):1263-74.
1997: Christopher K Glass; David W Rose; Michael G Rosenfeld
Nuclear receptor coactivators.
Current opinion in cell biology 1997;9(2):222-32.
1997: A E Horvai; Li Xu; Edward Korzus; Gyan Brard; D Kalafus; TM Mullen; David W Rose; Michael G Rosenfeld; Christopher K Glass
Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1074-9.
1997: G E DiMattia; S J Rhodes; Anna Krones; C Carrière; SM O'Connell; K Kalla; C Arias; P Sawchenko; Michael G Rosenfeld
The Pit-1 gene is regulated by distinct early and late pituitary-specific enhancers.
Developmental biology 1997;182(1):180-90.
1997: Eric M Jacobson; P Li; A Leon-del-Rio; Michael G Rosenfeld; Aneel K Aggarwal
Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility.
Genes & development 1997;11(2):198-212.
1996: Robert J McEvilly; L Erkman; L Luo; P E Sawchenko; Allen F Ryan; Michael G Rosenfeld
Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons.
Nature 1996;384(6609):574-7.
1996: M Treier; Michael G Rosenfeld
The hypothalamic-pituitary axis: co-development of two organs.
Current opinion in cell biology 1996;8(6):833-43.
1996: Simon J Rhodes; Anna Krones; C Nelson; Michael G Rosenfeld
Function of the conserved Pit-1 gene distal enhancer in progenitor and differentiated pituitary cells.
Molecular and cellular endocrinology 1996;124(1-2):163-72.
1996: M W Sornson; W Wu; Jeremy S Dasen; SE Flynn; D J Norman; SM O'Connell; I Gukovsky; C Carrière; Aimee Ryan; A P Miller; L Zuo; Anatoli Gleiberman; Bogi Andersen; W G Beamer; Michael G Rosenfeld
Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism.
Nature 1996;384(6607):327-33.
1996: Eric E Turner; Natalia Fedtsova; Michael G Rosenfeld
POU-domain factor expression in the trigeminal ganglion and implications for herpes virus regulation.
Neuroreport 1996;7(18):2829-32.
1996: I Zamir; H P Harding; G B Atkins; A Hörlein; Christopher K Glass; Michael G Rosenfeld; Mitchell Lazar
A nuclear hormone receptor corepressor mediates transcriptional silencing by receptors with distinct repression domains.
Molecular and cellular biology 1996;16(10):5458-65.
1996: DP Szeto; Aimee Ryan; SM O'Connell; Michael G Rosenfeld
P-OTX: a PIT-1-interacting homeodomain factor expressed during anterior pituitary gland development.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7706-10.
1996: Joanne M Yeakley; J P Morfin; Michael G Rosenfeld; Xiang-Dong Fu
A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7582-7.
1996: John R Bermingham; Steven S Scherer; SM O'Connell; Edgardo J Arroyo; K A Kalla; Frank L Powell; Michael G Rosenfeld
Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration.
Genes & development 1996;10(14):1751-62.
1996: L Erkman; Robert J McEvilly; L Luo; Aimee Ryan; Farideh Hooshmand; SM O'Connell; Elizabeth M Keithley; David H Rapaport; Allen F Ryan; Michael G Rosenfeld
Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.
Nature 1996;381(6583):603-6.
1996: Y Jiang; V C Yu; F Buchholz; SM O'Connell; Simon J Rhodes; C Candeloro; Y R Xia; A J Lusis; Michael G Rosenfeld
A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland.
The Journal of biological chemistry 1996;271(18):10723-30.
1996: Y Kamei; Li Xu; T Heinzel; Joseph Torchia; R Kurokawa; B Gloss; S C Lin; Richard A Heyman; David W Rose; Christopher K Glass; Michael G Rosenfeld
A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors.
Cell 1996;85(3):403-14.
1996: Michael G Rosenfeld; I Bach; L Erkman; P Li; C Lin; S Lin; Robert J McEvilly; A Ryan; Simon J Rhodes; M Schonnemann; K Scully
Transcriptional control of cell phenotypes in the neuroendocrine system.
Recent progress in hormone research 1996;51():217-38; discussion 238-9.
1995: M D Schonemann; Aimee Ryan; Robert J McEvilly; SM O'Connell; C A Arias; K A Kalla; P Li; P E Sawchenko; Michael G Rosenfeld
Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2.
Genes & development 1995;9(24):3122-35.
1995: Bogi Andersen; R V Pearse; K Jenne; M Sornson; S C Lin; A Bartke; Michael G Rosenfeld
The Ames dwarf gene is required for Pit-1 gene activation.
Developmental biology 1995;172(2):495-503.
1995: R Kurokawa; M Söderström; A Hörlein; Shlomit Halachmi; Myles Brown; Michael G Rosenfeld; Christopher K Glass
Polarity-specific activities of retinoic acid receptors determined by a co-repressor.
Nature 1995;377(6548):451-4.
1995: J M Holloway; DP Szeto; K M Scully; Christopher K Glass; Michael G Rosenfeld
Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain.
Genes & development 1995;9(16):1992-2006.
1995: Ingolf Bach; Simon J Rhodes; R V Pearse; T Heinzel; B Gloss; K M Scully; P E Sawchenko; Michael G Rosenfeld
P-Lim, a LIM homeodomain factor, is expressed during pituitary organ and cell commitment and synergizes with Pit-1.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2720-4.
1995: T Kishimoto; R V Pearse; C R Lin; Michael G Rosenfeld
A sauvagine/corticotropin-releasing factor receptor expressed in heart and skeletal muscle.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(4):1108-12.
1994: Bogi Andersen; Michael G Rosenfeld
Pit-1 determines cell types during development of the anterior pituitary gland. A model for transcriptional regulation of cell phenotypes in mammalian organogenesis.
The Journal of biological chemistry 1994;269(47):29335-8.
1994: R Kurokawa; J DiRenzo; Marcus F Boehm; J Sugarman; B Gloss; Michael G Rosenfeld; Richard A Heyman; Christopher K Glass
Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding.
Nature 1994;371(6497):528-31.
1994: Simon J Rhodes; G E DiMattia; Michael G Rosenfeld
Transcriptional mechanisms in anterior pituitary cell differentiation.
Current opinion in genetics & development 1994;4(5):709-17.
1994: S C Lin; S Li; D W Drolet; Michael G Rosenfeld
Pituitary ontogeny of the Snell dwarf mouse reveals Pit-1-independent and Pit-1-dependent origins of the thyrotrope.
Development (Cambridge, England) 1994;120(3):515-22.
1994: E E Turner; K J Jenne; Michael G Rosenfeld
Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid.
Neuron 1994;12(1):205-18.
1993: P Li; X He; M R Gerrero; M Mok; A Aggarwal; Michael G Rosenfeld
Spacing and orientation of bipartite DNA-binding motifs as potential functional determinants for POU domain factors.
Genes & development 1993;7(12B):2483-96.
1993: C P Chang; R V Pearse; S O'Connell; Michael G Rosenfeld
Identification of a seven transmembrane helix receptor for corticotropin-releasing factor and sauvagine in mammalian brain.
Neuron 1993;11(6):1187-95.
1993: J W Voss; L Wilson; Simon J Rhodes; Michael G Rosenfeld
An alternative Pit-1 RNA splicing product reveals modular binding and nonmodular transcriptional activities of the POU-specific domain.
Molecular endocrinology (Baltimore, Md.) 1993;7(12):1551-60.
1993: Bogi Andersen; R V Pearse; Peter N Schlegel; Z Cichon; M D Schonemann; CW Bardin; Michael G Rosenfeld
Sperm 1: a POU-domain gene transiently expressed immediately before meiosis I in the male germ cell.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11084-8.
1993: M R Gerrero; Robert J McEvilly; E Turner; C R Lin; SM O'Connell; K J Jenne; Monte V Hobbs; Michael G Rosenfeld
Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(22):10841-5.
1993: Bogi Andersen; M D Schonemann; R V Pearse; K Jenne; J Sugarman; Michael G Rosenfeld
Brn-5 is a divergent POU domain factor highly expressed in layer IV of the neocortex.
The Journal of biological chemistry 1993;268(31):23390-8.
1993: Joanne M Yeakley; F Hedjran; J P Morfin; N Merillat; Michael G Rosenfeld; Ronald B Emeson
Control of calcitonin/calcitonin gene-related peptide pre-mRNA processing by constitutive intron and exon elements.
Molecular and cellular biology 1993;13(10):5999-6011.
1993: C P Chang; C S Lazar; B J Walsh; M Komuro; J F Collawn; Leslie A Kuhn; J A Tainer; IS Trowbridge; M G Farquhar; Michael G Rosenfeld
Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors.
The Journal of biological chemistry 1993;268(26):19312-20.
1993: Steven M Lipkin; Anders M Näär; K A Kalla; R A Sack; Michael G Rosenfeld
Identification of a novel zinc finger protein binding a conserved element critical for Pit-1-dependent growth hormone gene expression.
Genes & development 1993;7(9):1674-87.
1993: S C Lin; C R Lin; I Gukovsky; A J Lusis; P E Sawchenko; Michael G Rosenfeld
Molecular basis of the little mouse phenotype and implications for cell type-specific growth.
Nature 1993;364(6434):208-13.
1993: R Kurokawa; V C Yu; Anders M Näär; Seiko Kyakumoto; Z Han; S Silverman; Michael G Rosenfeld; Christopher K Glass
Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.
Genes & development 1993;7(7B):1423-35.
1993: Simon J Rhodes; R Chen; G E DiMattia; K M Scully; K A Kalla; S C Lin; V C Yu; Michael G Rosenfeld
A tissue-specific enhancer confers Pit-1-dependent morphogen inducibility and autoregulation on the pit-1 gene.
Genes & development 1993;7(6):913-32.
1993: Michael Wegner; D W Drolet; Michael G Rosenfeld
POU-domain proteins: structure and function of developmental regulators.
Current opinion in cell biology 1993;5(3):488-98.
1993: Michael Wegner; D W Drolet; Michael G Rosenfeld
Regulation of JC virus by the POU-domain transcription factor Tst-1: implications for progressive multifocal leukoencephalopathy.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4743-7.
1993: sergio lira; K A Kalla; Christopher K Glass; D W Drolet; Michael G Rosenfeld
Synergistic interactions between Pit-1 and other elements are required for effective somatotroph rat growth hormone gene expression in transgenic mice.
Molecular endocrinology (Baltimore, Md.) 1993;7(5):694-701.
1993: B Andersen; M D Schonemann; S E Flynn; R V Pearse; H Singh; Michael G Rosenfeld
Skn-1a and Skn-1i: two functionally distinct Oct-2-related factors expressed in epidermis.
Science (New York, N.Y.) 1993;260(5104):78-82.
1993: E S Klein; Donna M Simmons; L W Swanson; Michael G Rosenfeld
Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein.
Genes & development 1993;7(1):55-71.
1992: C Lin; S C Lin; C P Chang; Michael G Rosenfeld
Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth.
Nature 1992;360(6406):765-8.
1992: V C Yu; Anders M Näär; Michael G Rosenfeld
Transcriptional regulation by the nuclear receptor superfamily.
Current opinion in biotechnology 1992;3(6):597-602.
1992: J W Voss; Michael G Rosenfeld
Anterior pituitary development: short tales from dwarf mice.
Cell 1992;70(4):527-30.
1992: C D Delsert; Michael G Rosenfeld
A tissue-specific small nuclear ribonucleoprotein and the regulated splicing of the calcitonin/calcitonin gene-related protein transcript.
The Journal of biological chemistry 1992;267(21):14573-9.
1992: J Michael Mathis; Donna M Simmons; X He; L W Swanson; Michael G Rosenfeld
Brain 4: a novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression.
The EMBO journal 1992;11(7):2551-61.
1992: Michael G Rosenfeld; Ronald B Emeson; Joanne M Yeakley; N Merillat; F Hedjran; J Lenz; C Delsert
Calcitonin gene-related peptide: a neuropeptide generated as a consequence of tissue-specific, developmentally regulated alternative RNA processing events.
Annals of the New York Academy of Sciences 1992;657():1-17.
1992: Ronald B Emeson; Joanne M Yeakley; F Hedjran; N Merillat; H J Lenz; Michael G Rosenfeld
Posttranscriptional regulation of calcitonin/CGRP gene expression.
Annals of the New York Academy of Sciences 1992;657():18-35.
1992: Michael Wegner; Z Cao; Michael G Rosenfeld
Calcium-regulated phosphorylation within the leucine zipper of C/EBP beta.
Science (New York, N.Y.) 1992;256(5055):370-3.
1992: Steven M Lipkin; C A Nelson; Christopher K Glass; Michael G Rosenfeld
A negative retinoic acid response element in the rat oxytocin promoter restricts transcriptional stimulation by heterologous transactivation domains.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1209-13.
1992: M N Treacy; L I Neilson; Eric E Turner; X He; Michael G Rosenfeld
Twin of I-POU: a two amino acid difference in the I-POU homeodomain distinguishes an activator from an inhibitor of transcription.
Cell 1992;68(3):491-505.
1992: Steven M Lipkin; Michael G Rosenfeld; Christopher K Glass
Regulation of gene expression by thyroid hormones and retinoic acid.
Genetic engineering 1992;14():185-209.
1991: V C Yu; C Delsert; B Andersen; J M Holloway; O V Devary; Anders M Näär; S Y Kim; J M Boutin; Christopher K Glass; Michael G Rosenfeld
RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements.
Cell 1991;67(6):1251-66.
1991: C P Chang; Joseph Kao; C S Lazar; B J Walsh; A Wells; H Steven Wiley; Gordon N Gill; Michael G Rosenfeld
Ligand-induced internalization and increased cell calcium are mediated via distinct structural elements in the carboxyl terminus of the epidermal growth factor receptor.
The Journal of biological chemistry 1991;266(34):23467-70.
1991: D W Drolet; K M Scully; Donna M Simmons; Michael Wegner; K T Chu; L W Swanson; Michael G Rosenfeld
TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins.
Genes & development 1991;5(10):1739-53.
1991: Michael Kapiloff; Y Farkash; Michael Wegner; Michael G Rosenfeld
Variable effects of phosphorylation of Pit-1 dictated by the DNA response elements.
Science (New York, N.Y.) 1991;253(5021):786-9.
1991: X He; Michael G Rosenfeld
Mechanisms of complex transcriptional regulation: implications for brain development.
Neuron 1991;7(2):183-96.
1991: J B Welsh; Gordon N Gill; Michael G Rosenfeld; A Wells
A negative feedback loop attenuates EGF-induced morphological changes.
The Journal of cell biology 1991;114(3):533-43.
1991: J W Voss; Tso-Pang Yao; Michael G Rosenfeld
Alternative translation initiation site usage results in two structurally distinct forms of Pit-1.
The Journal of biological chemistry 1991;266(20):12832-5.
1991: J W Voss; L Wilson; Michael G Rosenfeld
POU-domain proteins Pit-1 and Oct-1 interact to form a heteromeric complex and can cooperate to induce expression of the prolactin promoter.
Genes & development 1991;5(7):1309-20.
1991: Anders M Näär; J M Boutin; Steven M Lipkin; V C Yu; J M Holloway; Christopher K Glass; Michael G Rosenfeld
The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors.
Cell 1991;65(7):1267-79.
1991: H Steven Wiley; J J Herbst; B J Walsh; Douglas A Lauffenburger; Michael G Rosenfeld; Gordon N Gill
The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor.
The Journal of biological chemistry 1991;266(17):11083-94.
1991: Michael G Rosenfeld
POU-domain transcription factors: pou-er-ful developmental regulators.
Genes & development 1991;5(6):897-907.
1991: E B Crenshaw; A Ryan; S R Dillon; K Kalla; Michael G Rosenfeld
Wocko, a neurological mutant generated in a transgenic mouse pedigree.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(6):1524-30.
1991: Michael Kapiloff; J Michael Mathis; C A Nelson; C R Lin; Michael G Rosenfeld
Calcium/calmodulin-dependent protein kinase mediates a pathway for transcriptional regulation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3710-4.
1991: M N Treacy; X He; Michael G Rosenfeld
I-POU: a POU-domain protein that inhibits neuron-specific gene activation.
Nature 1991;350(6319):577-84.
1991: C D Carpenter; Holly A Ingraham; C Cochet; G M Walton; C S Lazar; J M Sowadski; Michael G Rosenfeld; Gordon N Gill
Structural analysis of the transmembrane domain of the epidermal growth factor receptor.
The Journal of biological chemistry 1991;266(9):5750-5.
1991: X He; R Gerrero; Donna M Simmons; R E Park; C J Lin; L W Swanson; Michael G Rosenfeld
Tst-1, a member of the POU domain gene family, binds the promoter of the gene encoding the cell surface adhesion molecule P0.
Molecular and cellular biology 1991;11(3):1739-44.
1990: K A Lund; C S Lazar; W S Chen; B J Walsh; J B Welsh; J J Herbst; G M Walton; Michael G Rosenfeld; Gordon N Gill; H Steven Wiley
Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation.
The Journal of biological chemistry 1990;265(33):20517-23.
1990: Christopher K Glass; O V Devary; Michael G Rosenfeld
Multiple cell type-specific proteins differentially regulate target sequence recognition by the alpha retinoic acid receptor.
Cell 1990;63(4):729-38.
1990: S Li; E B Crenshaw; E J Rawson; Donna M Simmons; L W Swanson; Michael G Rosenfeld
Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1.
Nature 1990;347(6293):528-33.
1990: J M Holloway; Christopher K Glass; S Adler; C A Nelson; Michael G Rosenfeld
The C'-terminal interaction domain of the thyroid hormone receptor confers the ability of the DNA site to dictate positive or negative transcriptional activity.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):8160-4.
1990: R P Chen; Holly A Ingraham; M N Treacy; V R Albert; L Wilson; Michael G Rosenfeld
Autoregulation of pit-1 gene expression mediated by two cis-active promoter elements.
Nature 1990;346(6284):583-6.
1990: Holly A Ingraham; SE Flynn; J W Voss; V R Albert; Michael Kapiloff; L Wilson; Michael G Rosenfeld
The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions.
Cell 1990;61(6):1021-33.
1990: Donna M Simmons; J W Voss; Holly A Ingraham; J M Holloway; R S Broide; Michael G Rosenfeld; L W Swanson
Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors.
Genes & development 1990;4(5):695-711.
1990: R Franco; Michael G Rosenfeld
Hormonally inducible phosphorylation of a nuclear pool of ribosomal protein S6.
The Journal of biological chemistry 1990;265(8):4321-5.
1990: L Stolarsky-Fredman; S E Leff; E S Klein; E B Crenshaw; Joanne M Yeakley; Michael G Rosenfeld
A tissue-specific enhancer in the rat-calcitonin/CGRP gene is active in both neural and endocrine cell types.
Molecular endocrinology (Baltimore, Md.) 1990;4(3):497-504.
1990: A Wells; J B Welsh; C S Lazar; H S Wiley; Gordon N Gill; Michael G Rosenfeld
Ligand-induced transformation by a noninternalizing epidermal growth factor receptor.
Science (New York, N.Y.) 1990;247(4945):962-4.
1990: G M Walton; W S Chen; Michael G Rosenfeld; Gordon N Gill
Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates.
The Journal of biological chemistry 1990;265(3):1750-4.
1990: H P Elsholtz; V R Albert; M N Treacy; Michael G Rosenfeld
A two-base change in a POU factor-binding site switches pituitary-specific to lymphoid-specific gene expression.
Genes & development 1990;4(1):43-51.
1989: S Li; E S Klein; A F Russo; Donna M Simmons; Michael G Rosenfeld
Isolation of cDNA clones encoding small nuclear ribonucleoparticle-associated proteins with different tissue specificities.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9778-82.
1989: Christopher K Glass; Steven M Lipkin; O V Devary; Michael G Rosenfeld
Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer.
Cell 1989;59(4):697-708.
1989: W S Chen; C S Lazar; K A Lund; J B Welsh; C P Chang; G M Walton; Channing J Der; H Steven Wiley; Gordon N Gill; Michael G Rosenfeld
Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation.
Cell 1989;59(1):33-43.
1989: Ronald B Emeson; F Hedjran; Joanne M Yeakley; J W Guise; Michael G Rosenfeld
Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor.
Nature 1989;341(6237):76-80.
1989: X He; M N Treacy; Donna M Simmons; Holly A Ingraham; L W Swanson; Michael G Rosenfeld
Expression of a large family of POU-domain regulatory genes in mammalian brain development.
Nature 1989;340(6228):35-41.
1989: E B Crenshaw; K Kalla; Donna M Simmons; L W Swanson; Michael G Rosenfeld
Cell-specific expression of the prolactin gene in transgenic mice is controlled by synergistic interactions between promoter and enhancer elements.
Genes & development 1989;3(7):959-72.
1989: H J Mangalam; V R Albert; Holly A Ingraham; Michael Kapiloff; L Wilson; C Nelson; H Elsholtz; Michael G Rosenfeld
A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally.
Genes & development 1989;3(7):946-58.
1988: Holly A Ingraham; R P Chen; H J Mangalam; H P Elsholtz; SE Flynn; C R Lin; Donna M Simmons; L Swanson; Michael G Rosenfeld
A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype.
Cell 1988;55(3):519-29.
1988: Eva Y-H P Lee; R Bookstein; L J Young; C J Lin; Michael G Rosenfeld; Wen-Hwa Lee
Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):6017-21.
1988: Christopher K Glass; J M Holloway; O V Devary; Michael G Rosenfeld
The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements.
Cell 1988;54(3):313-23.
1988: sergio lira; E B Crenshaw; Christopher K Glass; L W Swanson; Michael G Rosenfeld
Identification of rat growth hormone genomic sequences targeting pituitary expression in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(13):4755-9.
1988: A F Russo; E B Crenshaw; sergio lira; Donna M Simmons; L W Swanson; Michael G Rosenfeld
Neuronal expression of chimeric genes in transgenic mice.
Neuron 1988;1(4):311-20.
1988: C Nelson; V R Albert; H P Elsholtz; L I Lu; Michael G Rosenfeld
Activation of cell-specific expression of rat growth hormone and prolactin genes by a common transcription factor.
Science (New York, N.Y.) 1988;239(4846):1400-5.
1988: Paul J Bertics; W S Chen; L Hubler; C S Lazar; Michael G Rosenfeld; Gordon N Gill
Alteration of epidermal growth factor receptor activity by mutation of its primary carboxyl-terminal site of tyrosine self-phosphorylation.
The Journal of biological chemistry 1988;263(8):3610-7.
1988: S Adler; M L Waterman; X He; Michael G Rosenfeld
Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain.
Cell 1988;52(5):685-95.
1988: J R Glenney; W S Chen; C S Lazar; G M Walton; L M Zokas; Michael G Rosenfeld; Gordon N Gill
Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies.
Cell 1988;52(5):675-84.
1988: A F Russo; C Nelson; Bernard A Roos; Michael G Rosenfeld
Differential regulation of the coexpressed calcitonin/alpha-CGRP and beta-CGRP neuroendocrine genes.
The Journal of biological chemistry 1988;263(1):5-8.
1988: M L Waterman; S Adler; C Nelson; G L Greene; Ronald M Evans; Michael G Rosenfeld
A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene.
Molecular endocrinology (Baltimore, Md.) 1988;2(1):14-21.
1988: Michael G Rosenfeld; E B Crenshaw; sergio lira; L Swanson; E Borrelli; R Heyman; Ronald M Evans
Transgenic mice: applications to the study of the nervous system.
Annual review of neuroscience 1988;11():353-72.
1988: Michael G Rosenfeld; Christopher K Glass; S Adler; E B Crenshaw; X He; sergio lira; H P Elsholtz; H J Mangalam; J M Holloway; C Nelson
Response and binding elements for ligand-dependent positive transcription factors integrate positive and negative regulation of gene expression.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():545-56.
1988: Gordon N Gill; W S Chen; C S Lazar; J R Glenney; H Steven Wiley; Holly A Ingraham; Michael G Rosenfeld
Role of intrinsic protein tyrosine kinase in function and metabolism of the epidermal growth factor receptor.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():467-76.
1988: Gordon N Gill; Michael G Rosenfeld; W S Chen; Paul J Bertics; C S Lazar
Analysis of functional domains in the epidermal growth factor receptor using site-directed mutagenesis.
Advances in experimental medicine and biology 1988;234():91-103.
1987: Christopher K Glass; R Franco; C Weinberger; V R Albert; Ronald M Evans; Michael G Rosenfeld
A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone.
Nature 1987;329(6141):738-41.
1987: C R Lin; Michael Kapiloff; S Durgerian; K Tatemoto; A F Russo; P Hanson; H Schulman; Michael G Rosenfeld
Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5962-6.
1987: E B Crenshaw; A F Russo; L W Swanson; Michael G Rosenfeld
Neuron-specific alternative RNA processing in transgenic mice expressing a metallothionein-calcitonin fusion gene.
Cell 1987;49(3):389-98.
1987: Michael G Rosenfeld; C Nelson; E B Crenshaw; H P Elsholtz; sergio lira; H J Mangalam; R Franco; M Waterman; C Weinberger; S M Hollenberg
Developmental and hormonal regulation of neuroendocrine gene transcription.
Recent progress in hormone research 1987;43():499-534.
1986: H P Elsholtz; H J Mangalam; E Potter; V R Albert; S Supowit; Ronald M Evans; Michael G Rosenfeld
Two different cis-active elements transfer the transcriptional effects of both EGF and phorbol esters.
Science (New York, N.Y.) 1986;234(4783):1552-7.
1986: C Nelson; E B Crenshaw; R Franco; sergio lira; V R Albert; R M Evans; Michael G Rosenfeld
Discrete cis-active genomic sequences dictate the pituitary cell type-specific expression of rat prolactin and growth hormone genes.
Nature 1986;322(6079):557-62.
1986: C R Lin; W S Chen; C S Lazar; C D Carpenter; Gordon N Gill; R M Evans; Michael G Rosenfeld
Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms.
Cell 1986;44(6):839-48.
1986: C Weinberger; V Giguere; S Hollenberg; Michael G Rosenfeld; Ronald M Evans
Human steroid receptors and erbA proto-oncogene products: members of a new superfamily of enhancer binding proteins.
Cold Spring Harbor symposia on quantitative biology 1986;51 Pt 2():759-72.
1985: C Weinberger; S M Hollenberg; Michael G Rosenfeld; Ronald M Evans
Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product.
Nature 1985;318(6047):670-2.
1985: S M Hollenberg; C Weinberger; E S Ong; G Cerelli; A Oro; R Lebo; E B Thompson; Michael G Rosenfeld; Ronald M Evans
Primary structure and expression of a functional human glucocorticoid receptor cDNA.
Nature 1985;318(6047):635-41.
1985: C Weinberger; S M Hollenberg; E S Ong; Jeffrey M Harmon; Steven Brower; J Cidlowski; E Brad Thompson; Michael G Rosenfeld; Ronald M Evans
Identification of human glucocorticoid receptor complementary DNA clones by epitope selection.
Science (New York, N.Y.) 1985;228(4700):740-2.
1985: Ronald M Evans; C Weinberger; S Hollenberg; L Swanson; C Nelson; Michael G Rosenfeld
Inducible and developmental control of neuroendocrine genes.
Cold Spring Harbor symposia on quantitative biology 1985;50():389-97.