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Allen Roses

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Allen D Roses; Ann M Saunders; Donna G Crenshaw; Iris Grossman; Michael W Lutz; W Kirby Gottschalk
TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial.
D G Crenshaw; W K Gottschalk; Iris Grossman; M W Lutz; S K Brannan; J R Burke; D K Burns; Ann M Saunders; Kathleen A Welsh-Bohmer; Allen D Roses
Using genetics to enable studies on the prevention of Alzheimer's disease.
Ornit Chiba-Falek; Stephen D Gardner; John Guyton; Colton Linnertz; Jeanette J McCarthy; Allen D Roses; Keyur Patel
Pleiotropy and allelic heterogeneity in the TOMM40-APOE genomic region related to clinical and metabolic features of hepatitis C infection.

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All Publications

2013: Allen D Roses; Ann M Saunders; Donna G Crenshaw; Iris Grossman; Michael W Lutz; W Kirby Gottschalk
TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2013;9(2):132-6.
2013: D G Crenshaw; W K Gottschalk; Iris Grossman; M W Lutz; S K Brannan; J R Burke; D K Burns; Ann M Saunders; Kathleen A Welsh-Bohmer; Allen D Roses
Using genetics to enable studies on the prevention of Alzheimer's disease.
Clinical pharmacology and therapeutics 2013;93(2):177-85.
2012: Ornit Chiba-Falek; Stephen D Gardner; John Guyton; Colton Linnertz; Jeanette J McCarthy; Allen D Roses; Keyur Patel
Pleiotropy and allelic heterogeneity in the TOMM40-APOE genomic region related to clinical and metabolic features of hepatitis C infection.
Human genetics 2012;131(12):1911-20.
2012: Kathleen M Hayden; Maragatha Kuchibhatla; Colton Linnertz; Michael W Lutz; Jill M McEvoy; Allen D Roses; Ann M Saunders; Kathleen A Welsh-Bohmer; Deborah Attix; Ornit Chiba-Falek
A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2012;8(5):381-8.
2012: Colton Linnertz; Michael W Lutz; Jeanette J McCarthy; Allen D Roses; Ann M Saunders; Megan Ulmer; Kathleen A Welsh-Bohmer; Keith E Whitfield; Rand Allingham; Daniel K Burns; Donna M Crenshaw; Iris Grossman; Michael A Hauser; Ornit Chiba-Falek
Characterization of the poly-T variant in the TOMM40 gene in diverse populations.
PloS one 2012;7(2):e30994.
2011: Nunzio Pomara; Davide Bruno; David J Greenblatt; Michael W Lutz; Ann M Saunders; John J Sidtis; Allen D Roses
Translocase of outer mitochondrial membrane 40 homolog (TOMM40) poly-T length modulates lorazepam-related cognitive toxicity in healthy APOE ε4-negative elderly.
Journal of clinical psychopharmacology 2011;31(4):544-6.
2011: Sterling C Johnson; Erin M Jonaitis; Rebecca L Koscik; Asenath La Rue; Michael W Lutz; Allen D Roses; Sanjay Asthana; Barbara B Bendlin; Robert C Green; Bruce P Hermann; Kirk J Hogan; Ann M Saunders; Guofan Xu; Mark A Sager
The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotype.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2011;7(4):456-65.
2011: Michael W Lutz; Donna G Crenshaw; Ann M Saunders; Allen D Roses
The importance of being connected.
Journal of Alzheimer's disease : JAD 2011;24(2):247-51.
2010: Ara S Khachaturian; Joab Chapman; Lindsay Farrer; Robert P Friedland; Richard Ebstein; Iris Grossman; Talma Hendler; Bruce Hermann; Rivka Inzelberg; Sterling Johnson; ZAVEN KHACHATURIAN; Irit Lichter-Shapira; Oksana Makeeva; Robin Mayrl; Eli Mizrahi; Allen D Roses; Mark Sager; Shifra Fraifeld
Healthy aging and preclinical dementia: the United States-Israel Longitudinal Database project.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2010;6(6):475-81.
2010: Allen D Roses; M W Lutz; H Amrine-Madsen; Ann M Saunders; D G Crenshaw; S S Sundseth; Matthew Huentelman; K A Welsh-Bohmer; Eric Reiman
A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease.
The pharmacogenomics journal 2010;10(5):375-84.
2010: S Ferguson; B Mouzon; G Kayihan; M Wood; F Poon; S Doore; Venkatarajan S Mathura; James Humphrey; B O'Steen; R Hayes; Allen D Roses; Michael Mullan; Fiona Crawford
Apolipoprotein E genotype and oxidative stress response to traumatic brain injury.
Neuroscience 2010;168(3):811-9.
2010: P Muglia; F Tozzi; N W Galwey; C Francks; R Upmanyu; X Q Kong; A Antoniades; E Domenici; J Perry; S Rothen; C L Vandeleur; V Mooser; G Waeber; P Vollenweider; M Preisig; S Lucae; B Müller-Myhsok; F Holsboer; L T Middleton; Allen D Roses
Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts.
Molecular psychiatry 2010;15(6):589-601.
2010: Allen D Roses
An inherited variable poly-T repeat genotype in TOMM40 in Alzheimer disease.
Archives of neurology 2010;67(5):536-41.
2010: Michael W Lutz; Donna G Crenshaw; Ann M Saunders; Allen D Roses
Genetic variation at a single locus and age of onset for Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2010;6(2):125-31.
2010: ZAVEN KHACHATURIAN; Deborah Barnes; Richard Einstein; Sterling Johnson; Virginia M-Y Lee; Allen D Roses; Mark A Sager; William R Shankle; Peter J Snyder; Ronald C. Petersen; Gerard D Schellenberg; John Q Trojanowski; Paul Aisen; Marilyn S Albert; John C S Breitner; Neil Buckholtz; Maria Carrillo; Steven Ferris; Barry D Greenberg; Michael Grundman; Ara S Khachaturian; Lewis H Kuller; Oscar L Lopez; Paul Maruff; Richard C Mohs; Marcelle Morrison-Bogorad; Creighton Phelps; Eric Reiman; Marwan Sabbagh; Mary Sano; Lon S Schneider; Eric Siemers; Pierre Tariot; Jacques Touchon; Bruno Vellas; Lisa J Bain
Developing a national strategy to prevent dementia: Leon Thal Symposium 2009.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2010;6(2):89-97.
2010: Erin L Heinzen; Anna C Need; Kathleen M Hayden; Ornit Chiba-Falek; Allen D Roses; Warren J Strittmatter; James R Burke; Christine M Hulette; Kathleen A Welsh-Bohmer; David B Goldstein
Genome-wide scan of copy number variation in late-onset Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;19(1):69-77.
2009: Laura J Scott; Pierandrea Muglia; Xiangyang Q Kong; Weihua Guan; Matthew Flickinger; Ruchi Upmanyu; Federica Tozzi; Jun Z Li; Margit Burmeister; Devin Absher; Robert C Thompson; Clyde Francks; Fan Meng; Athos Antoniades; Audrey M Southwick; Alan F Schatzberg; William E Bunney; Jack D Barchas; Edward G Jones; Richard Day; Keith Matthews; Peter McGuffin; John S Strauss; James L Kennedy; Lefkos Middleton; Allen D Roses; Stanley J Watson Jr; John B Vincent; Richard Myers; Ann E Farmer; Huda Akil; Daniel K Burns; Michael Boehnke
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(18):7501-6.
2009: Fiona Crawford; M Wood; S Ferguson; Venkatarajan S Mathura; P Gupta; James Humphrey; B Mouzon; V Laporte; E Margenthaler; B O'Steen; R Hayes; Allen D Roses; Michael Mullan
Apolipoprotein E-genotype dependent hippocampal and cortical responses to traumatic brain injury.
Neuroscience 2009;159(4):1349-62.
2009: Allen D Roses
Stimulation of cholecystokinin-A receptors with Gl181771X: a failed clinical trial that did not test the pharmacogenetic hypothesis for reduction of food intake.
Clinical pharmacology and therapeutics 2009;85(4):362-5.
2009: X Lin; K Song; N Lim; X Yuan; T Johnson; A Abderrahmani; P Vollenweider; H Stirnadel; S S Sundseth; E Lai; D K Burns; L T Middleton; Allen D Roses; Paul Matthews; Gerard Waeber; L Cardon; D M Waterworth; V Mooser
Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study.
Diabetologia 2009;52(4):600-8.
2009: ZAVEN KHACHATURIAN; Peter J Snyder; Rachelle S Doody; Paul S Aisen; Meryl Comer; John Dwyer; Richard A Frank; Andrew Holzapfel; Ara Khachaturian; Amos D Korczyn; Allen D Roses; James W Simpkins; Lon S Schneider; Marilyn S Albert; Robert Egge; Aaron Deves; Steven Ferris; Barry D Greenberg; Carl Johnson; Walter A Kukull; Judes Poirier; Dale Schenk; William Thies; S Gauthier; Sid Gilman; Charles Bernick; Jeffrey L Cummings; Howard Fillit; Michael Grundman; Jeffrey A Kaye; Lennart Mucke; Barry Reisberg; Mary Sano; Oxana Pickeral; Ronald C. Petersen; Richard C Mohs; Maria Carrillo; Jody Corey-Bloom; Norman L Foster; Steve Jacobsen; Virginia M-Y Lee; William Z Potter; Marwan Sabbagh; David P Salmon; John Q Trojanowski; Nancy Wexler; Lisa J Bain
A roadmap for the prevention of dementia II: Leon Thal Symposium 2008.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2009;5(2):85-92.
2009: Sreekumar G Pillai; Dongliang Ge; Guohua Zhu; Xiangyang Kong; Kevin V Shianna; Anna C Need; Sheng Feng; Craig P Hersh; Per Bakke; Amund Gulsvik; Andreas Ruppert; Karin C Lødrup Carlsen; Allen D Roses; Wayne Anderson; Stephen I Rennard; David A Lomas; Edwin K Silverman; David B Goldstein
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.
PLoS genetics 2009;5(3):e1000421.
2009: Anna C Need; Dongliang Ge; Michael E Weale; Jessica Maia; Sheng Feng; Erin L Heinzen; Kevin V Shianna; Woohyun Yoon; Dalia Kasperaviciūte; Massimo Gennarelli; Warren J Strittmatter; Cristian Bonvicini; Giuseppe Rossi; Karu Jayathilake; Philip A Cola; Joseph P McEvoy; Richard S E Keefe; Elizabeth M C Fisher; Pamela L St Jean; Ina Giegling; Annette M Hartmann; Hans-Jürgen Möller; Andreas Ruppert; Gillian Fraser; Caroline Crombie; Lefkos T Middleton; David St Clair; Allen D Roses; Pierandrea Muglia; Clyde Francks; Dan Rujescu; Herbert Y Meltzer; David B Goldstein
A genome-wide investigation of SNPs and CNVs in schizophrenia.
PLoS genetics 2009;5(2):e1000373.
2009: Matthew Nelson; S-A Bacanu; M Mosteller; L Li; C E Bowman; Allen D Roses; E H Lai; M G Ehm
Genome-wide approaches to identify pharmacogenetic contributions to adverse drug reactions.
The pharmacogenomics journal 2009;9(1):23-33.
2009: P Anthony Akkari; Thomas W Swanson; Donna G Crenshaw; Iris Grossman; Scott Sundseth; Daniel K Burns; Allen D Roses
Pipeline pharmacogenetics: a novel approach to integrating pharmaco-genetics into drug development.
Current pharmaceutical design 2009;15(32):3754-63.
2009: Allen D Roses
The medical and economic roles of pipeline pharmacogenetics: Alzheimer's disease as a model of efficacy and HLA-B(*)5701 as a model of safety.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(1):6-17.
2008: A R Hughes; W R Spreen; M Mosteller; L L Warren; E H Lai; C H Brothers; C Cox; A J Nelsen; S Hughes; D E Thorborn; B Stancil; S V Hetherington; D K Burns; Allen D Roses
Pharmacogenetics of hypersensitivity to abacavir: from PGx hypothesis to confirmation to clinical utility.
The pharmacogenomics journal 2008;8(6):365-74.
2008: Allen D Roses
Pharmacogenetics in drug discovery and development: a translational perspective.
Nature reviews. Drug discovery 2008;7(10):807-17.
2008: Emma L Akuffo; John B Davis; Steven M Fox; Israel S Gloger; David Hosford; Emma E Kinsey; Neil A Jones; Christina M Nock; Allen D Roses; Ann M Saunders; J Mark Skehel; Marjorie A Smith; Paul Cutler
The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2008;13(6):618-36.
2008: Matthew Nelson; Katarzyna Bryc; Karen S King; Amit Indap; Adam R Boyko; John Novembre; Linda P Briley; Yuka Maruyama; Dawn M Waterworth; Gerard Waeber; Peter Vollenweider; Jorge R Oksenberg; Stephen L Hauser; Heide A Stirnadel; Jaspal S Kooner; John C Chambers; Brendan Jones; Vincent Mooser; Carlos Bustamante; Allen D Roses; Daniel K Burns; Margaret G Ehm; Eric H Lai
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research.
American journal of human genetics 2008;83(3):347-58.
2008: Anna C Need; Deborah K Attix; Jill M McEvoy; Elizabeth T Cirulli; Kristen N Linney; Ana Patricia Wagoner; Curtis E Gumbs; Ina Giegling; Hans-Jürgen Möller; Clyde Francks; Pierandrea Muglia; Allen D Roses; Greg Gibson; Mike E Weale; Dan Rujescu; David B Goldstein
Failure to replicate effect of Kibra on human memory in two large cohorts of European origin.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(5):667-8.
2008: Christian Netzer; Jan Freudenberg; Axel Heinze; Katja Heinze-Kuhn; Ingrid Goebel; Linda C McCarthy; Allen D Roses; Hartmut Göbel; Unda Todt; Christian Kubisch
Replication study of the insulin receptor gene in migraine with aura.
Genomics 2008;91(6):503-7.
2008: Allen D Roses
Commentary on "a roadmap for the prevention of dementia: the inaugural Leon Thal Symposium." An impending prevention clinical trial for Alzheimer's disease: roadmaps and realities.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2008;4(3):164-6.
2008: John P Cogswell; James Ward; Ian Taylor; Michelle Waters; Yunling Shi; Brian Cannon; Kevin Kelnar; Jon Kemppainen; David Brown; Caifu Chen; Rab Prinjha; Jill C Richardson; Ann M Saunders; Allen D Roses; Cynthia A Richards
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways.
Journal of Alzheimer's disease : JAD 2008;14(1):27-41.
2008: Paul Cutler; Emma L Akuffo; Wanda M Bodnar; Deborah M Briggs; John B Davis; Christine M Debouck; Steven M Fox; Rachel A Gibson; Darren A Gormley; Joanna D Holbrook; A Jacqueline Hunter; Emma E Kinsey; Rab Prinjha; Jill C Richardson; Allen D Roses; Marjorie A Smith; Nikos Tsokanas; David R Willé; Wen Wu; John W Yates; Israel S Gloger
Proteomic identification and early validation of complement 1 inhibitor and pigment epithelium-derived factor: Two novel biomarkers of Alzheimer's disease in human plasma.
Proteomics. Clinical applications 2008;2(4):467-77.
2008: Jens Brodbeck; Maureen E Balestra; Ann M Saunders; Allen D Roses; Robert W Mahley; Yadong Huang
Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(4):1343-6.
2008: Hao Li; Sally Wetten; Li Li; Pamela L St Jean; Ruchi Upmanyu; Linda Surh; David Hosford; Michael R Barnes; James David Briley; Michael Borrie; Natalie Coletta; Richard Delisle; Daniella Dhalla; Margaret G Ehm; Howard H Feldman; Luis Fornazzari; S Gauthier; Neil Goodgame; Danilo Guzman; Sandra Hammond; Paul Hollingworth; Ging-Yuek Hsiung; Joan Johnson; Devon D Kelly; Ron Keren; Andrew Kertesz; Karen S King; Simon Lovestone; Inge Loy-English; Paul Matthews; Michael J Owen; Mary Plumpton; William Pryse-Phillips; Rab Prinjha; Jill C Richardson; Ann M Saunders; Andrew J Slater; Peter St George-Hyslop; Sandra W Stinnett; Jina Swartz; Rachel L Taylor; John Wherrett; Julie Williams; David P Yarnall; Rachel A Gibson; Michael C Irizarry; Lefkos T Middleton; Allen D Roses
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
Archives of neurology 2008;65(1):45-53.
2008: G Zhu; K Carlsen; K-H Carlsen; Warren Lenney; M Silverman; M K Whyte; Louise K Hosking; Peter J Helms; Allen D Roses; D W Hay; M R Barnes; Wayne H Anderson; Sreekumar Pillai
Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations.
Genes and immunity 2008;9(1):23-9.
2007: Allen D Roses; Pamela L St Jean; Margaret G Ehm
Use of whole-genome association scans in disease gene identification, drug discovery and development.
IDrugs : the investigational drugs journal 2007;10(11):797-804.
2007: Allen D Roses
"Personalized medicine: elusive dream or imminent reality?": A commentary.
Clinical pharmacology and therapeutics 2007;81(6):801-5.
2007: L L Warren; Arlene R Hughes; Eric H Lai; D V Zaykin; S A Haneline; A T Bansal; A W Wooster; William Spreen; Jaime E Hernandez; Trevor R Scott; Allen D Roses; Michael Mosteller
Use of pairwise marker combination and recursive partitioning in a pharmacogenetic genome-wide scan.
The pharmacogenomics journal 2007;7(3):180-9.
2007: Jay C Strum; Ron Shehee; David J Virley; Jill Richardson; Michael Mattie; Paula Selley; Sujoy Ghosh; Christina Nock; Ann M Saunders; Allen D Roses
Rosiglitazone induces mitochondrial biogenesis in mouse brain.
Journal of Alzheimer's disease : JAD 2007;11(1):45-51.
2007: Allen D Roses; Ann M Saunders; Y Huang; J Strum; Karl H Weisgraber; R W Mahley
Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease).
The pharmacogenomics journal 2007;7(1):10-28.
2006: M E Risner; Ann M Saunders; J F B Altman; G C Ormandy; Suzanne Craft; I M Foley; M E Zvartau-Hind; D A Hosford; Allen D Roses
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease.
The pharmacogenomics journal 2006;6(4):246-54.
2006: Allen D Roses; Ann M Saunders
Perspective on a pathogenesis and treatment of Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2006;2(2):59-70.
2006: Jim Stankovich; Charles J Cox; Rachel B Tan; Douglas S Montgomery; Stewart J Huxtable; Justin P Rubio; Margaret G Ehm; Laura Johnson; Helmut Butzkueven; Trevor J Kilpatrick; Terence P Speed; Allen D Roses; Melanie Bahlo; Simon J Foote
On the utility of data from the International HapMap Project for Australian association studies.
Human genetics 2006;119(1-2):220-2.
2006: Allen D Roses
On the discovery of the genetic association of Apolipoprotein E genotypes and common late-onset Alzheimer disease.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):361-6.
2005: Colin F Spraggs; Sreekumar Pillai; David Dow; Christal Douglas; Linda McCarthy; Penelope K Manasco; Michael Stubbins; Allen D Roses
Pharmacogenetics and obesity: common gene variants influence weight loss response of the norepinephrine/dopamine transporter inhibitor GW320659 in obese subjects.
Pharmacogenetics and genomics 2005;15(12):883-9.
2005: Allen D Roses
Applying technologies towards safe and effective medicines.
BioTechniques 2005;39(10 Suppl):S563-4.
2005: Allen D Roses
Applying technologies towards safe and effective medicines.
BioTechniques 2005;39(4):563-4.
2005: Allen D Roses; Daniel K Burns; Stephanie Chissoe; Lefkos T Middleton; Pamela St Jean
Disease-specific target selection: a critical first step down the right road.
Drug discovery today 2005;10(3):177-89.
2005: Chang Liu; Sujoy Ghosh; David B Searls; Ann M Saunders; Jeffrey Cossman; Allen D Roses
Clusters of adjacent and similarly expressed genes across normal human tissues complicate comparative transcriptomic discovery.
Omics : a journal of integrative biology 2005;9(4):351-63.
2005: Kourosh R Ahmadi; Michael E Weale; Zhengyu Y Xue; Nicole Soranzo; David P Yarnall; James D Briley; Yuka Maruyama; Mikiro Kobayashi; Nicholas W Wood; Nigel K Spurr; Daniel K Burns; Allen D Roses; Ann M Saunders; David B Goldstein
A single-nucleotide polymorphism tagging set for human drug metabolism and transport.
Nature genetics 2005;37(1):84-9.
2004: Kristin K Nicodemus; Judith E Stenger; Donald E Schmechel; Kathleen A Welsh-Bohmer; Ann M Saunders; Allen D Roses; John Gilbert; Jeffery Vance; Jonathan L Haines; Margaret Pericak-Vance; Eden R Martin
Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease.
Neurogenetics 2004;5(4):201-8.
2004: Allen D Roses
Pharmacogenetics and drug development: the path to safer and more effective drugs.
Nature reviews. Genetics 2004;5(9):645-56.
2004: Christopher P Austin; James F Battey; Allan Bradley; Maja Bucan; Mario R Capecchi; Francis S Collins; William F Dove; Geoffrey Duyk; Susan Dymecki; Janan T Eppig; Franziska B Grieder; Nathaniel Heintz; Geoff Hicks; Thomas R Insel; Alexandra L Joyner; Beverly H Koller; K C Kent Lloyd; Terry Magnuson; Mark W Moore; Andras Nagy; Jonathan D Pollock; Allen D Roses; Arthur T Sands; Brian Seed; William C Skarnes; Jay Snoddy; Philippe Soriano; David J Stewart; Francis Stewart; Bruce Stillman; Harold Varmus; Lyuba Varticovski; Inder M Verma; Thomas F Vogt; Harald von Melchner; Jan Witkowski; Richard P Woychik; Wolfgang Wurst; George D Yancopoulos; Stephen G Young; Brian Zambrowicz
The knockout mouse project.
Nature genetics 2004;36(9):921-4.
2004: Elizabeth R Hauser; David C Crossman; Christopher B Granger; Jonathan L Haines; Christopher J H Jones; Vincent Mooser; Brendan McAdam; Bernhard R Winkelmann; Alan H Wiseman; J Brent Muhlestein; Alan G Bartel; Charles A Dennis; Elaine Dowdy; Susan Estabrooks; Karen Eggleston; Sheila Francis; Kath Roche; Paula W Clevenger; Liling Huang; Bonnie Pedersen; Svati Shah; Silke Schmidt; Carol Haynes; Sandra G West; Donny Asper; Michael Booze; Sanjay Sharma; Scott Sundseth; Lefkos Middleton; Allen D Roses; Michael A Hauser; Jeffery Vance; Margaret Pericak-Vance; William E Kraus
A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study.
American journal of human genetics 2004;75(3):436-47.
2004: Joelle M van der Walt; Yulia A Dementieva; Eden R Martin; William Scott; Kristin K Nicodemus; Charles C Kroner; Kathleen A Welsh-Bohmer; Ann M Saunders; Allen D Roses; Gary W Small; Donald E Schmechel; P Murali Doraiswamy; John Gilbert; Jonathan L Haines; Jeffery Vance; Margaret Pericak-Vance
Analysis of European mitochondrial haplogroups with Alzheimer disease risk.
Neuroscience letters 2004;365(1):28-32.
2004: Bernard V North; David Curtis; Eden R Martin; Eric H Lai; Allen D Roses; Pak C Sham
Further investigation of linkage disequilibrium SNPs and their ability to identify associated susceptibility loci.
Annals of human genetics 2004;68(Pt 3):240-8.
2004: David A Hosford; Eric H Lai; John H Riley; Chun-Fang Xu; Theodore M Danoff; Allen D Roses
Pharmacogenetics to predict drug-related adverse events.
Toxicologic pathology 2004;32 Suppl 1():9-12.
2004: Arlene R Hughes; Michael Mosteller; Aruna T Bansal; Kirstie Davies; Stephen A Haneline; Eric H Lai; Keith Nangle; Trevor Scott; William Spreen; Liling L Warren; Allen D Roses
Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations.
Pharmacogenomics 2004;5(2):203-11.
2004: Chun-Fang Xu; K F Lewis; A J Yeo; Linda C McCarthy; M F Maguire; Z Anwar; Theodore M Danoff; Allen D Roses; Ian Purvis
Identification of a pharmacogenetic effect by linkage disequilibrium mapping.
The pharmacogenomics journal 2004;4(6):374-8.
2004: Theodore M Danoff; D A Campbell; Linda C McCarthy; K F Lewis; M H Repasch; Ann M Saunders; Nigel K Spurr; Ian Purvis; Allen D Roses; Chun-Fang Xu
A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia.
The pharmacogenomics journal 2004;4(1):49-53.
2003: Yi-Ju Li; Sofia A Oliveira; Puting Xu; Eden R Martin; Judith E Stenger; Clemens R Scherzer; Michael A Hauser; William Scott; Gary W Small; Martha A Nance; Ray L Watts; Jean P Hubble; William Koller; Rajesh Pahwa; Matthew B Stern; Bradley C Hiner; Joseph Jankovic; Christopher G Goetz; Frank L Mastaglia; Lefkos T Middleton; Allen D Roses; Ann M Saunders; Donald E Schmechel; Steven R Gullans; Jonathan L Haines; John Gilbert; Jeffery Vance; Margaret Pericak-Vance; Christine M Hulette; Kathleen A Welsh-Bohmer
Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease.
Human molecular genetics 2003;12(24):3259-67.
2003: William Scott; Elizabeth R Hauser; Donald E Schmechel; Kathleen A Welsh-Bohmer; Gary W Small; Allen D Roses; Ann M Saunders; John Gilbert; Jeffery Vance; Jonathan L Haines; Margaret Pericak-Vance
Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22.
American journal of human genetics 2003;73(5):1041-51.
2003: Sofia A Oliveira; Eden R Martin; William Scott; Kristin K Nicodemus; Gary W Small; Donald E Schmechel; P Murali Doraiswamy; Allen D Roses; Ann M Saunders; John Gilbert; Jonathan L Haines; Jeffery Vance; Margaret Pericak-Vance
The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease.
Neuroscience letters 2003;347(3):143-6.
2003: V D Schmith; D A Campbell; S Sehgal; Wayne H Anderson; D K Burns; L T Middleton; Allen D Roses
Pharmacogenetics and disease genetics of complex diseases.
Cellular and molecular life sciences : CMLS 2003;60(8):1636-46.
2003: Ofir Levi; Ana L Jongen-Relo; Joram Feldon; Allen D Roses; Daniel M Michaelson
ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory.
Neurobiology of disease 2003;13(3):273-82.
2003: Joelle M van der Walt; Eden R Martin; William Scott; Fengyu Zhang; Martha A Nance; Ray L Watts; Jean P Hubble; Jonathan L Haines; William Koller; Kelly E Lyons; Rajesh Pahwa; Matthew B Stern; Amy Colcher; Bradley C Hiner; Joseph Jankovic; William G Ondo; Fred H Allen; Christopher G Goetz; Gary W Small; Frank L Mastaglia; Allen D Roses; Jeffrey M Stajich; Michael W Booze; Kenichiro Fujiwara; R A Gibson; Lefkos T Middleton; Burton L Scott; Margaret Pericak-Vance; Jeffery Vance
Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease.
Neurology 2003;60(7):1189-91.
2003: Elizabeth R Hauser; Vincent Mooser; David C Crossman; Jonathan L Haines; Christopher H Jones; Bernhard R Winkelmann; Silke Schmidt; William Scott; Allen D Roses; Margaret Pericak-Vance; Christopher B Granger; William E Kraus
Design of the Genetics of Early Onset Cardiovascular Disease (GENECARD) study.
American heart journal 2003;145(4):602-13.
2003: Paul W Norbert; Allen D Roses
Pharmacogenetics and pharmacogenomics: recent developments, their clinical relevance and some ethical, social, and legal implications.
Journal of molecular medicine (Berlin, Germany) 2003;81(3):135-40.
2003: Allen D Roses; Menelas Pangalos
Drug development and Alzheimer disease.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2003;11(2):123-30.
2003: Gal Ophir; Sigal Meilin; Margalit Efrati; Joab Chapman; Dimitrios Karussis; Allen D Roses; Daniel M Michaelson
Human apoE3 but not apoE4 rescues impaired astrocyte activation in apoE null mice.
Neurobiology of disease 2003;12(1):56-64.
2003: Y Ezra; L Oron; L Moskovich; Allen D Roses; Sara M Beni; Esther Shohami; Daniel M Michaelson
Apolipoprotein E4 decreases whereas apolipoprotein E3 increases the level of secreted amyloid precursor protein after closed head injury.
Neuroscience 2003;121(2):315-25.
2002: Eric Lai; Clive Bowman; Aruna Bansal; Arlene Hughes; Michael Mosteller; Allen D Roses
Medical applications of haplotype-based SNP maps: learning to walk before we run.
Nature genetics 2002;32(3):353.
2002: Allen D Roses
Genome-based pharmacogenetics and the pharmaceutical industry.
Nature reviews. Drug discovery 2002;1(7):541-9.
2002: Bruce Teter; Pu-Ting Xu; John Gilbert; Allen D Roses; Douglas Galasko; Gregory M. Cole
Defective neuronal sprouting by human apolipoprotein E4 is a gain-of-negative function.
Journal of neuroscience research 2002;68(3):331-6.
2002: Yi-Ju Li; William Scott; Dale Hedges; Fengyu Zhang; P Craig Gaskell; Martha A Nance; Ray L Watts; Jean P Hubble; William Koller; Rajesh Pahwa; Matthew B Stern; Bradley C Hiner; Joseph Jankovic; Fred A Allen; Christopher G Goetz; Frank Mastaglia; Jeffrey M Stajich; Rachel A Gibson; Lefkos T Middleton; Ann M Saunders; Burton L Scott; Gary W Small; Kristin K Nicodemus; Allison D Reed; Donald E Schmechel; Kathleen A Welsh-Bohmer; P Michael Conneally; Allen D Roses; John Gilbert; Jeffery Vance; Jonathan L Haines; Margaret Pericak-Vance
Age at onset in two common neurodegenerative diseases is genetically controlled.
American journal of human genetics 2002;70(4):985-93.
2002: Seth Hetherington; Arlene R Hughes; Michael Mosteller; Denise Shortino; Katherine L Baker; William Spreen; Eric Lai; Kirstie Davies; Abigail Handley; David J Dow; Mary E Fling; Michael Stocum; Clive Bowman; Linda M Thurmond; Allen D Roses
Genetic variations in HLA-B region and hypersensitivity reactions to abacavir.
Lancet 2002;359(9312):1121-2.
2002: Duncan Hewett; Lena Samuelsson; Joanne Polding; Fredrik Enlund; Devi Smart; Kathryn Cantone; Chee Gee See; Sapna Chadha; Annica Inerot; Charlotta Enerback; Doug Montgomery; Chris Christodolou; Phil Robinson; Paul Matthews; Mary Plumpton; Jan L Wahlstrom; Gunnar Swanbeck; Tommy Martinsson; Allen D Roses; John Riley; Ian Purvis
Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map.
Genomics 2002;79(3):305-14.
2002: Allen D Roses
Pharmacogenetics place in modern medical science and practice.
Life sciences 2002;70(13):1471-80.
2002: Allen D Roses
SNPs--where's the beef?
The pharmacogenomics journal 2002;2(5):277-83.
2001: L C McCarthy; D A Hosford; J H Riley; M I Bird; N J White; D R Hewett; S J Peroutka; L R Griffiths; P R Boyd; R A Lea; S M Bhatti; L K Hosking; C M Hood; K W Jones; A R Handley; R Rallan; K F Lewis; A J Yeo; P M Williams; R C Priest; P Khan; C Donnelly; S M Lumsden; J O'Sullivan; Chee Gee See; D H Smart; S Shaw-Hawkins; J Patel; T C Langrish; W Feniuk; R G Knowles; M Thomas; V Libri; D S Montgomery; P K Manasco; C F Xu; C Dykes; P P Humphrey; Allen D Roses; I J Purvis
Single-nucleotide polymorphism alleles in the insulin receptor gene are associated with typical migraine.
Genomics 2001;78(3):135-49.
2001: Eden R Martin; William Scott; M A Nance; Ray L Watts; Jean P Hubble; William Koller; Kelly E Lyons; Rajesh Pahwa; Matthew B Stern; A Colcher; B C Hiner; Joseph Jankovic; William G Ondo; F H Allen; Christopher G Goetz; Gary W Small; D Masterman; F Mastaglia; N G Laing; J M Stajich; R C Ribble; M W Booze; A Rogala; M A Hauser; F Zhang; R A Gibson; L T Middleton; Allen D Roses; Jonathan L Haines; B L Scott; Margaret Pericak-Vance; Jeffery Vance
Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease.
JAMA : the journal of the American Medical Association 2001;286(18):2245-50.
2001: William Scott; M A Nance; Ray L Watts; Jean P Hubble; William Koller; Kelly E Lyons; Rajesh Pahwa; Matthew B Stern; A Colcher; B C Hiner; Joseph Jankovic; William G Ondo; F H Allen; Christopher G Goetz; Gary W Small; D Masterman; F Mastaglia; N G Laing; J M Stajich; B Slotterbeck; M W Booze; R C Ribble; Evadnie Rampersaud; Sandra G West; R A Gibson; L T Middleton; Allen D Roses; Jonathan L Haines; B L Scott; Jeffery Vance; Margaret Pericak-Vance
Complete genomic screen in Parkinson disease: evidence for multiple genes.
JAMA : the journal of the American Medical Association 2001;286(18):2239-44.
2001: Allen D Roses
2025: the practice of neurology: back from the future.
Archives of neurology 2001;58(11):1766-7.
2001: Allen D Roses
Pharmacogenetics.
Human molecular genetics 2001;10(20):2261-7.
2001: F White; Nicoll James; Allen D Roses; Karen Horsburgh
Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion.
Neurobiology of disease 2001;8(4):611-25.
2000: Karen Horsburgh; James McCulloch; Margaret Nilsen; Allen D Roses; Nicoll James
Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia.
The European journal of neuroscience 2000;12(12):4309-17.
2000: Margaret Pericak-Vance; Janet Grubber; L R Bailey; Dale Hedges; Sandra G West; L Santoro; B Kemmerer; J L Hall; Ann M Saunders; Allen D Roses; Gary W Small; William Scott; PM Conneally; Jeffery Vance; Jonathan L Haines
Identification of novel genes in late-onset Alzheimer's disease.
Experimental gerontology 2000;35(9-10):1343-52.
2000: Allen D Roses
Genetic susceptibility to cardiovascular diseases.
American heart journal 2000;140(4):S45-7.
2000: M R Wilkins; Allen D Roses; CP Clifford
Pharmacogenetics and the treatment of cardiovascular disease.
Heart (British Cardiac Society) 2000;84(4):353-4.
2000: Allen D Roses
Idiosyncratic reactions to drugs: can medicine response profiles provide a dynamic drug surveillance system?
Clinical chemistry and laboratory medicine : CCLM / FESCC 2000;38(9):815-8.
2000: Eden R Martin; Eric H Lai; John Gilbert; AR Rogala; A J Afshari; John Riley; K L Finch; J F Stevens; K J Livak; BD Slotterbeck; Susan H Slifer; LL Warren; PM Conneally; Donald E Schmechel; Ian Purvis; Margaret Pericak-Vance; Allen D Roses; Jeffery Vance
SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease.
American journal of human genetics 2000;67(2):383-94.
2000: John Mounsey; J Edward John; Steve M Helmke; EW Bush; John Gilbert; Allen D Roses; M Benjamin Perryman; Larry R Jones; J Randall Moorman
Phospholemman is a substrate for myotonic dystrophy protein kinase.
The Journal of biological chemistry 2000;275(30):23362-7.
2000: Ann M Saunders; M K Trowers; R A Shimkets; SJ Blakemore; D J Crowther; T A Mansfield; Douglas Wallace; Warren J Strittmatter; Allen D Roses
The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection.
Biochimica et biophysica acta 2000;1502(1):85-94.
2000: Allen D Roses
Pharmacogenetics and the practice of medicine.
Nature 2000;405(6788):857-65.
2000: Gary W Small; Linda M Ercoli; Daniel H S Silverman; Sung-Cheng Huang; Scott Komo; Susan Y Bookheimer; Helen Lavretsky; Karen Miller; Prabha Siddarth; Natalie Rasgon; John C Mazziotta; Sanjaya Saxena; H M Wu; Michael S Mega; Jeffrey L Cummings; Ann M Saunders; Margaret Pericak-Vance; Allen D Roses; Jorge R Barrio; Michael E Phelps
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6037-42.
2000: Allen D Roses
Causes or consequences of inflammation and pathological signs of Alzheimer disease.
Neurobiology of aging 2000;21(3):423-5.
2000: Allen D Roses
Pharmacogenetics and future drug development and delivery.
Lancet 2000;355(9212):1358-61.
2000: Jingwen Chen; Marie A Iannone; May Li Shih; J David Taylor; P Rivers; A J Nelsen; KA Slentz-Kesler; Allen D Roses; Michael P Weiner
A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension.
Genome research 2000;10(4):549-57.
2000: Kathryn P Riley; David A Snowdon; Ann M Saunders; Allen D Roses; James A Mortimer; N Nanayakkara
Cognitive function and apolipoprotein E in very old adults: findings from the Nun Study.
The journals of gerontology. Series B, Psychological sciences and social sciences 2000;55(2):S69-75.
2000: Karen Horsburgh; James McCulloch; Margaret Nilsen; Eileen McCracken; CH Large; Allen D Roses; Nicoll James
Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(3):458-62.
2000: William Scott; Janet Grubber; PM Conneally; Gary W Small; Christine M Hulette; CK Rosenberg; Ann M Saunders; Allen D Roses; Jonathan L Haines; Margaret Pericak-Vance
Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity.
American journal of human genetics 2000;66(3):922-32.
2000: J H Riley; C J Allan; E Lai; Allen D Roses
The use of single nucleotide polymorphisms in the isolation of common disease genes.
Pharmacogenomics 2000;1(1):39-47.
2000: T Sabo; Liat Lomnitski; Abraham Nyska; Sara M Beni; R R Maronpot; Esther Shohami; Allen D Roses; Daniel M Michaelson
Susceptibility of transgenic mice expressing human apolipoprotein E to closed head injury: the allele E3 is neuroprotective whereas E4 increases fatalities.
Neuroscience 2000;101(4):879-84.
2000: Allen D Roses
Pharmacogenetics and pharmacogenomics in the discovery and development of medicines.
Novartis Foundation symposium 2000;229():63-6; discussion 66-70.
2000: S Chapman; T Sabo; Allen D Roses; Daniel M Michaelson
Reversal of presynaptic deficits of apolipoprotein E-deficient mice in human apolipoprotein E transgenic mice.
Neuroscience 2000;97(3):419-24.
2000: Eden R Martin; John Gilbert; Eric H Lai; John Riley; AR Rogala; BD Slotterbeck; C A Sipe; Janet Grubber; LL Warren; PM Conneally; Ann M Saunders; Donald E Schmechel; Ian Purvis; Margaret Pericak-Vance; Allen D Roses; Jeffery Vance
Analysis of association at single nucleotide polymorphisms in the APOE region.
Genomics 2000;63(1):7-12.
1999: U Boschert; E Merlo-Pich; G Higgins; Allen D Roses; Stefan Catsicas
Apolipoprotein E expression by neurons surviving excitotoxic stress.
Neurobiology of disease 1999;6(6):508-14.
1999: Bruce Teter; Pu-Ting Xu; John Gilbert; Allen D Roses; Douglas Galasko; Gregory M. Cole
Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture.
Journal of neurochemistry 1999;73(6):2613-6.
1999: William Scott; LH Yamaoka; Jeffrey M Stajich; Burton L Scott; Jeffery Vance; Allen D Roses; Margaret Pericak-Vance; Ray L Watts; Martha Nance; Jean P Hubble; William Koller; Matthew B Stern; Amy Colcher; F H Allen; Bradley C Hiner; Joseph Jankovic; William G Ondo; N G Laing; F Mastaglia; Christopher G Goetz; E Pappert; Gary W Small; D Masterman; Jonathan L Haines; T L Davies
The alpha-synuclein gene is not a major risk factor in familial Parkinson disease.
Neurogenetics 1999;2(3):191-2.
1999: Gary W Small; William Scott; Scott Komo; LH Yamaoka; Lindsay A Farrer; S H Auerbach; Ann M Saunders; Allen D Roses; Jonathan L Haines; Margaret Pericak-Vance
No association between the HLA-A2 allele and Alzheimer disease.
Neurogenetics 1999;2(3):177-82.
1999: Christine M Hulette; Margaret Pericak-Vance; Allen D Roses; Donald E Schmechel; LH Yamaoka; Perry C Gaskell; Kathleen A Welsh-Bohmer; R A Crowther; Maria Grazia Spillantini
Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684.
Journal of neuropathology and experimental neurology 1999;58(8):859-66.
1999: Janet Grubber; Ann M Saunders; A R Crane-Gatherum; William Scott; Eden R Martin; CS Haynes; PM Conneally; Gary W Small; Allen D Roses; Jonathan L Haines; Margaret Pericak-Vance
Analysis of association between Alzheimer disease and the K variant of butyrylcholinesterase (BCHE-K).
Neuroscience letters 1999;269(2):115-9.
1999: Gary W Small; Stephen T Chen; Scott Komo; Linda M Ercoli; Susan Y Bookheimer; Karen Miller; Helen Lavretsky; Sanjaya Saxena; A Kaplan; D Dorsey; William Scott; Ann M Saunders; Jonathan L Haines; Allen D Roses; Margaret Pericak-Vance
Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele.
The American journal of psychiatry 1999;156(7):1035-8.
1999: E A Rogaeva; S Premkumar; Janet Grubber; L Serneels; William Scott; T Kawarai; Y Song; D L Hill; S M Abou-Donia; Eden R Martin; Jeffery Vance; Gang G. Yu; A Orlacchio; Y Pei; M Nishimura; Agnes Supala; B Roberge; Ann M Saunders; Allen D Roses; Donald E Schmechel; A Crane-Gatherum; Sandro Sorbi; A Bruni; Gary W Small; P M Conneally; Jonathan L Haines; Fred Van Leuven; Peter St George-Hyslop; Lindsay A Farrer; Margaret Pericak-Vance
An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease.
Nature genetics 1999;22(1):19-22.
1999: Karen Horsburgh; S Kelly; James McCulloch; G A Higgins; Allen D Roses; Nicoll James
Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia.
Neuroreport 1999;10(4):837-41.
1999: William Scott; Janet Grubber; S M Abou-Donia; T D Church; Ann M Saunders; Allen D Roses; Margaret Pericak-Vance; PM Conneally; Gary W Small; Jonathan L Haines
Further evidence linking late-onset Alzheimer disease with chromosome 12.
JAMA : the journal of the American Medical Association 1999;281(6):513-4.
1999: Pu-Ting Xu; Donald E Schmechel; HL Qiu; Michael H Herbstreith; TR Rothrock-Christian; M Eyster; Allen D Roses; John Gilbert
Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice.
Neurobiology of disease 1999;6(1):63-75.
1998: Gillian Einstein; V Patel; P Bautista; M Kenna; L Melone; R Fader; K Karson; S Mann; Ann M Saunders; Christine M Hulette; Deborah C Mash; Allen D Roses; Donald E Schmechel
Intraneuronal ApoE in human visual cortical areas reflects the staging of Alzheimer disease pathology.
Journal of neuropathology and experimental neurology 1998;57(12):1190-201.
1998: Allen D Roses
Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg.
Annals of the New York Academy of Sciences 1998;855():738-43.
1998: E Lai; John Riley; Ian Purvis; Allen D Roses
A 4-Mb high-density single nucleotide polymorphism-based map around human APOE.
Genomics 1998;54(1):31-8.
1998: Lindsay A Farrer; Carmela Abraham; Jonathan L Haines; Ekaterina Rogaeva; Y Song; WT McGraw; N Brindle; S Premkumar; William Scott; LH Yamaoka; Ann M Saunders; Allen D Roses; SA Auerbach; Sandro Sorbi; Ranjan Duara; Margaret Pericak-Vance; Peter St George-Hyslop
Association between bleomycin hydrolase and Alzheimer's disease in caucasians.
Annals of neurology 1998;44(5):808-11.
1998: K R Williams; Ann M Saunders; Allen D Roses; Patricia J Armati
Uptake and internalization of exogenous apolipoprotein E3 by cultured human central nervous system neurons.
Neurobiology of disease 1998;5(4):271-9.
1998: Allen D Roses
Patent income.
Science (New York, N.Y.) 1998;281(5384):1805.
1998: John Gilbert; V Guy; A Kumar; C Wolpert; R Kandt; A Aylesworth; Allen D Roses; Margaret Pericak-Vance
Mutation and polymorphism analysis in the tuberous sclerosis 2 (TSC2) gene.
Neurogenetics 1998;1(4):267-72.
1998: Meredyth P Bass; LH Yamaoka; William Scott; Perry C Gaskell; Kathleen A Welsh-Bohmer; Allen D Roses; Ann M Saunders; Jonathan L Haines; Margaret Pericak-Vance
No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients.
Neuroscience letters 1998;250(2):79-82.
1998: Mirta Mihovilovic; Y Mai; C Austin; Allen D Roses
Sera from myasthenia gravis patients recognize the PEVK domain of titin.
Annals of the New York Academy of Sciences 1998;841():534-7.
1998: Mirta Mihovilovic; S Denning; Y Mai; C M Fisher; LP Whichard; Dhavalkumar D Patel; Allen D Roses
Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5, and beta-4 subunits of neuronal nicotinic acetylcholine receptors. Preferential transcription of the alpha-3 and beta-4 genes by immature CD4+8+ thymocytes and evidence for response to nicotine in thymocytes.
Annals of the New York Academy of Sciences 1998;841():388-92.
1998: Akira Tamaoka; Paul E Fraser; Kazuhiro Ishii; N Sahara; K Ozawa; Masaki Ikeda; Ann M Saunders; Yasuko Komatsuzaki; R Sherrington; Georges Levesque; Gang G. Yu; Ekaterina Rogaeva; Shin'ichi Shoji; Linda E Nee; Daniel A Pollen; L Hendriks; J J Martin; Christine Van Broeckhoven; Allen D Roses; Lindsay A Farrer; Peter St George-Hyslop; Hiroshi Mori
Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease.
Brain research. Molecular brain research 1998;56(1-2):178-85.
1998: Daniel T Laskowitz; K Horsburgh; Allen D Roses
Apolipoprotein E and the CNS response to injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(5):465-71.
1998: Pu-Ting Xu; John Gilbert; HL Qiu; TR Rothrock-Christian; D L Settles; Allen D Roses; Donald E Schmechel
Regionally specific neuronal expression of human APOE gene in transgenic mice.
Neuroscience letters 1998;246(2):65-8.
1998: B L Scott; K Welch; V deSerrano; N C Moss; Allen D Roses; Warren J Strittmatter
Human apolipoprotein E accelerates microtubule polymerization in vitro.
Neuroscience letters 1998;245(2):105-8.
1998: Huaxin Sheng; Daniel T Laskowitz; E Bennett; Donald E Schmechel; RD Bart; Ann M Saunders; Robert D Pearlstein; Allen D Roses; David S Warner
Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(4):361-6.
1998: Allen D Roses
Genetic associations.
Lancet 1998;351(9106):916.
1998: William Scott; LH Yamaoka; Meredyth P Bass; Perry C Gaskell; PM Conneally; Gary W Small; Lindsay A Farrer; SA Auerbach; Ann M Saunders; Allen D Roses; Jonathan L Haines; Margaret Pericak-Vance
No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease.
Neurogenetics 1998;1(3):179-83.
1998: John R Guyton; Sara E Miller; M E Martin; Wasiuddin A Khan; Allen D Roses; Warren J Strittmatter
Novel large apolipoprotein E-containing lipoproteins of density 1.006-1.060 g/ml in human cerebrospinal fluid.
Journal of neurochemistry 1998;70(3):1235-40.
1998: Richard Mayeux; Ann M Saunders; S Shea; Suzanne S Mirra; Denis A Evans; Allen D Roses; Bradley T Hyman; Barbara J Crain; Ming-Xin Tang; C H Phelps
Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease.
The New England journal of medicine 1998;338(8):506-11.
1998: Allen D Roses
Alzheimer diseases: a model of gene mutations and susceptibility polymorphisms for complex psychiatric diseases.
American journal of medical genetics 1998;81(1):49-57.
1998: Allen D Roses
Genetic testing and Alzheimer disease: the promise.
Alzheimer disease and associated disorders 1998;12 Suppl 3():S3-9.
1998: A M Thomas; G Cohen; R M Cook-Deegan; J O'Sullivan; S G Post; Allen D Roses; K F Schaffner; R M Green
Alzheimer testing at Silver Years.
Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees 1998;7(3):294-307.
1998: Allen D Roses; John Gilbert; Pu-Ting Xu; Patrick M. Sullivan; Brian Popko; D S Burkhart; T Christian-Rothrock; Ann M Saunders; Nobuyo Maeda; Donald E Schmechel
Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice.
Neurobiology of aging 1998;19(1 Suppl):S53-8.
1998: Margaret Pericak-Vance; M L Bass; LH Yamaoka; Perry C Gaskell; William Scott; H A Terwedow; Marisa M Menold; PM Conneally; Gary W Small; Ann M Saunders; Allen D Roses; Jonathan L Haines
Complete genomic screen in late-onset familial Alzheimer's disease.
Neurobiology of aging 1998;19(1 Suppl):S39-42.
1998: Terry A Robertson; Nichole Dutton; Ralph N Martins; Allen D Roses; Byron A Kakulas; John M Papadimitriou
Age-related congophilic inclusions in the brains of apolipoprotein E-deficient mice.
Neuroscience 1998;82(1):171-80.
1997: M Okochi; Kazuhiro Ishii; Mihoko Usami; N Sahara; Fuyuki Kametani; K Tanaka; Paul E Fraser; Masaki Ikeda; Ann M Saunders; L Hendriks; Shin'ichi Shoji; Linda E Nee; J J Martin; Christine Van Broeckhoven; Peter St George-Hyslop; Allen D Roses; Hiroshi Mori
Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations.
FEBS letters 1997;418(1-2):162-6.
1997: Arthur J L Cooper; K R Sheu; James R Burke; Osamu Onodera; Warren J Strittmatter; Allen D Roses; John P Blass
Transglutaminase-catalyzed inactivation of glyceraldehyde 3-phosphate dehydrogenase and alpha-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(23):12604-9.
1997: Mirta Mihovilovic; S Denning; Y Mai; LP Whichard; Dhavalkumar D Patel; Allen D Roses
Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5 and beta-4 subunits of neuronal nicotinic acetylcholine receptors: preferential transcription of the alpha-3 and beta-4 genes by immature CD4 + 8 + thymocytes.
Journal of neuroimmunology 1997;79(2):176-84.
1997: Margaret Pericak-Vance; Meredyth P Bass; LH Yamaoka; Perry C Gaskell; William Scott; H A Terwedow; Marisa M Menold; PM Conneally; Gary W Small; Jeffery Vance; Ann M Saunders; Allen D Roses; Jonathan L Haines
Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.
JAMA : the journal of the American Medical Association 1997;278(15):1237-41.
1997: Jeffrey M Stajich; JM Gilchrist; F Lennon; A Lee; LH Yamaoka; B Rosi; Perry C Gaskell; M Pritchard; L Donald; Allen D Roses; Jeffery Vance; Margaret Pericak-Vance
Confirmation of linkage of oculopharyngeal muscular dystrophy to chromosome 14q11.2-q13 in American families suggests the existence of a second causal mutation.
Neuromuscular disorders : NMD 1997;7 Suppl 1():S75-81.
1997: Allen D Roses
Genetic testing for Alzheimer disease. Practical and ethical issues.
Archives of neurology 1997;54(10):1226-9.
1997: Allen D Roses; Ann M Saunders
ApoE, Alzheimer's disease, and recovery from brain stress.
Annals of the New York Academy of Sciences 1997;826():200-12.
1997: Noriaki Mitsuda; Allen D Roses; Michael P. Vitek
Transcriptional regulation of the mouse presenilin-1 gene.
The Journal of biological chemistry 1997;272(38):23489-97.
1997: Osamu Onodera; James R Burke; Sara E Miller; S Hester; S Tsuji; Allen D Roses; Warren J Strittmatter
Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells.
Biochemical and biophysical research communications 1997;238(2):599-605.
1997: Marcy C Speer; Margaret Pericak-Vance; Jeffrey M Stajich; J Sarrica; M Jordan; Allen D Roses; Jeffery Vance; John Gilbert
Further exclusion of FSHD1B from the telomeric region of 10q.
Neurogenetics 1997;1(2):151-2.
1997: Barbara E Tardiff; Mark F Newman; Ann M Saunders; Warren J Strittmatter; James A Blumenthal; William D White; ND Croughwell; R Duane Davis; Allen D Roses; Joseph Gerald Reves
Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center.
The Annals of thoracic surgery 1997;64(3):715-20.
1997: William Scott; Ann M Saunders; Perry C Gaskell; P A Locke; John H Growdon; Lindsay A Farrer; SA Auerbach; Allen D Roses; Jonathan L Haines; Margaret Pericak-Vance
Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease.
Annals of neurology 1997;42(3):376-8.
1997: Kathleen A Welsh-Bohmer; Marla Gearing; Ann M Saunders; Allen D Roses; Suzanne S Mirra
Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease.
Annals of neurology 1997;42(3):319-25.
1997: William Scott; J M Staijich; LH Yamaoka; Marcy C Speer; Jeffery Vance; Allen D Roses; Margaret Pericak-Vance
Genetic complexity and Parkinson's disease. Deane Laboratory Parkinson Disease Research Group.
Science (New York, N.Y.) 1997;277(5324):387-8; author reply 389.
1997: Allen D Roses
Alzheimer's disease: the genetics of risk.
Hospital practice (1995) 1997;32(7):51-5, 58-63, 67-9.
1997: Daniel T Laskowitz; Huaxin Sheng; RD Bart; K A Joyner; Allen D Roses; David S Warner
Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(7):753-8.
1997: Arthur J L Cooper; KF Sheu; James R Burke; Osamu Onodera; Warren J Strittmatter; Allen D Roses; John P Blass
Polyglutamine domains are substrates of tissue transglutaminase: does transglutaminase play a role in expanded CAG/poly-Q neurodegenerative diseases?
Journal of neurochemistry 1997;69(1):431-4.
1997: Allen D Roses; Ann M Saunders
Clinical overdiagnosis of vascular dementia versus necropsy confirmed series.
Journal of neurology, neurosurgery, and psychiatry 1997;62(6):677-8.
1997: Christine M Hulette; K A Welsh-Bohmer; Barbara J Crain; M H Szymanski; N O Sinclaire; Allen D Roses
Rapid brain autopsy. The Joseph and Kathleen Bryan Alzheimer's Disease Research Center experience.
Archives of pathology & laboratory medicine 1997;121(6):615-8.
1997: Gene Alexander; Ann M Saunders; J Szczepanik; TL Strassburger; Pietro Pietrini; A Dani; Maura L Furey; Marc J Mentis; Allen D Roses; Stanley I Rapoport; Mark B Schapiro
Relation of age and apolipoprotein E to cognitive function in Down syndrome adults.
Neuroreport 1997;8(8):1835-40.
1997: Allen D Roses
A model for susceptibility polymorphisms for complex diseases: apolipoprotein E and Alzheimer disease.
Neurogenetics 1997;1(1):3-11.
1997: Mark J Alberts; J P Davis; Carmelo Graffagnino; C McClenny; David DeLong; Christopher Granger; Michael H Herbstreith; K Boteva; Douglas A Marchuk; Allen D Roses
Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage.
Annals of neurology 1997;41(5):683-6.
1997: Stephen G Post; Peter J Whitehouse; Robert H Binstock; Thomas D Bird; S K Eckert; Lindsay A Farrer; L M Fleck; Atwood D Gaines; Eric T Juengst; H Karlinsky; S Miles; Thomas H Murray; Kimberly Quaid; Norman Richard Relkin; Allen D Roses; Peter St George-Hyslop; Greg A. Sachs; B Steinbock; E F Truschke; A B Zinn
The clinical introduction of genetic testing for Alzheimer disease. An ethical perspective.
JAMA : the journal of the American Medical Association 1997;277(10):832-6.
1997: SH Barondes; Bruce Alberts; N C Andreasen; Cornelia I Bargmann; F Benes; P Goldman-Rakic; Irving GOTTESMAN; S F Heinemann; E G Jones; M Kirschner; D Lewis; M Raff; Allen D Roses; J Rubenstein; Solomon H Snyder; Stanley J Watson Jr; Daniel R Weinberger; Robert H Yolken
Workshop on schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(5):1612-4.
1997: Allen D Roses
Mutational and susceptibility genetics are different clinical paradigms.
International psychogeriatrics / IPA 1997;9(1):7-10.
1997: Gary W Small; Ernest P Noble; S S Matsuyama; Lissy Jarvik; Scott Komo; A Kaplan; Terry Ritchie; M L Pritchard; Ann M Saunders; P M Conneally; Allen D Roses; Jonathan L Haines; Margaret Pericak-Vance
D2 dopamine receptor A1 allele in Alzheimer disease and aging.
Archives of neurology 1997;54(3):281-5.
1997: Allen D Roses; Ann M Saunders
Prediction for unimpaired subjects is different from diagnosis of demented patients.
Annals of neurology 1997;41(3):414-6.
1997: Carol F Lippa; T W Smith; Ann M Saunders; Christine M Hulette; D Pulaski-Salo; Allen D Roses
Apolipoprotein E-epsilon 2 and Alzheimer's disease: genotype influences pathologic phenotype.
Neurology 1997;48(2):515-9.
1997: Terry A Robertson; Nichole Dutton; Ralph N Martins; Allen D Roses; Byron A Kakulas; John M Papadimitriou
Beta-amyloid protein-containing inclusions in skeletal muscle of apolipoprotein-E-deficient mice.
The American journal of pathology 1997;150(2):417-27.
1997: Allen D Roses; Ann M Saunders
Apolipoprotein E genotyping as a diagnostic adjunct for Alzheimer's disease.
International psychogeriatrics / IPA 1997;9 Suppl 1():277-88; discussion 317-21.
1997: Allen D Roses
Apolipoprotein E, a gene with complex biological interactions in the aging brain.
Neurobiology of disease 1997;4(3-4):170-85.
1997: K R Williams; V Pye; Ann M Saunders; Allen D Roses; Patricia J Armati
Apolipoprotein E uptake and low-density lipoprotein receptor-related protein expression by the NTera2/D1 cell line: a cell culture model of relevance for late-onset Alzheimer's disease.
Neurobiology of disease 1997;4(1):58-67.
1997: William Scott; LH Yamaoka; P A Locke; B L Rosi; Perry C Gaskell; Ann M Saunders; PM Conneally; Gary W Small; Lindsay A Farrer; John H Growdon; Allen D Roses; Margaret Pericak-Vance; Jonathan L Haines
No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease.
Genetic epidemiology 1997;14(3):307-15.
1997: A Kumar; R S Kandt; C Wolpert; Allen D Roses; Margaret Pericak-Vance; John Gilbert
A novel splice site mutation (156 + 1G-->A) in the TSC2 gene.
Human mutation 1997;9(1):64-5.
1996: Allen D Roses; Ann M Saunders
Evaluation of suspected dementia.
The New England journal of medicine 1996;335(26):1996; author reply 1997-8.
1996: Gary W Small; Scott Komo; Asenath La Rue; S Saxena; Michael E Phelps; John C Mazziotta; Ann M Saunders; Jonathan L Haines; Margaret Pericak-Vance; Allen D Roses
Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging.
Annals of the New York Academy of Sciences 1996;802():70-8.
1996: Allen D Roses
Apolipoprotein E and Alzheimer's disease. A rapidly expanding field with medical and epidemiological consequences.
Annals of the New York Academy of Sciences 1996;802():50-7.
1996: Jonathan L Haines; M L Pritchard; Ann M Saunders; J M Schildkraut; John H Growdon; Perry C Gaskell; Lindsay A Farrer; S A Auerbach; James Gusella; P A Locke; B L Rosi; LH Yamaoka; Gary W Small; P M Conneally; Allen D Roses; Margaret Pericak-Vance
No association between alpha 1-antichymotrypsin and familial Alzheimer's disease.
Annals of the New York Academy of Sciences 1996;802():35-41.
1996: Osamu Onodera; Allen D Roses; S Tsuji; Jeffery Vance; Warren J Strittmatter; James R Burke
Toxicity of expanded polyglutamine-domain proteins in Escherichia coli.
FEBS letters 1996;399(1-2):135-9.
1996: Allen D Roses; J Bryan; K Bryan
Apolipoprotein E genotype: utility in clinical practice in Alzheimer's disease.
Journal of the American Geriatrics Society 1996;44(12):1479-81.
1996: LH Yamaoka; Kathleen A Welsh-Bohmer; Christine M Hulette; Perry C Gaskell; M Murray; J L Rimmler; B R Helms; M Guerra; Allen D Roses; Donald E Schmechel; Margaret Pericak-Vance
Linkage of frontotemporal dementia to chromosome 17: clinical and neuropathological characterization of phenotype.
American journal of human genetics 1996;59(6):1306-12.
1996: Jeffrey M Stajich; JM Gilchrist; F Lennon; A Lee; LH Yamaoka; B Helms; Perry C Gaskell; L Donald; Allen D Roses; Jeffery Vance; Margaret Pericak-Vance
Confirmation of linkage of oculopharyngeal muscular dystrophy to chromosome 14q11.2-q13.
Annals of neurology 1996;40(5):801-4.
1996: Allen D Roses
The Alzheimer diseases.
Current opinion in neurobiology 1996;6(5):644-50.
1996: Allen D Roses
Apolipoprotein E in neurology.
Current opinion in neurology 1996;9(4):265-70.
1996: Valerie Askanas; W King Engel; M Mirabella; Karl H Weisgraber; Ann M Saunders; Allen D Roses; Janis McFerrin
Apolipoprotein E alleles in sporadic inclusion-body myositis and hereditary inclusion-body myopathy.
Annals of neurology 1996;40(2):264-5.
1996: K Okuizumi; Osamu Onodera; K Seki; Hajime Tanaka; Y Namba; K Ikeda; Ann M Saunders; Margaret Pericak-Vance; Allen D Roses; S Tsuji
Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease.
Annals of neurology 1996;40(2):251-4.
1996: Y Xia; H A Rohan de Silva; B L Rosi; LH Yamaoka; J B Rimmler; Margaret Pericak-Vance; Allen D Roses; X Chen; Eliezer Masliah; R DeTeresa; A Iwai; M Sundsmo; Ronald Thomas; C R Hofstetter; E Gregory; Lawrence A Hansen; Robert Katzman; Leon J Thal; T Saitoh
Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism.
Annals of neurology 1996;40(2):207-15.
1996: Jonathan L Haines; M Ter-Minassian; A Bazyk; James Gusella; D J Kim; H Terwedow; Margaret Pericak-Vance; Jacqueline B Rimmler; C S Haynes; Allen D Roses; A Lee; B Shaner; M Menold; Eric Seboun; R P Fitoussi; C Gartioux; C Reyes; F Ribierre; Gabor Gyapay; Jean Weissenbach; Stephen L Hauser; D E Goodkin; R Lincoln; K Usuku; J R Oksenberg
A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group.
Nature genetics 1996;13(4):469-71.
1996: William Scott; Allen D Roses; Jonathan L Haines; Margaret Pericak-Vance
Presenilin-1 polymorphism and Alzheimer's disease.
Lancet 1996;347(9014):1560.
1996: M L Pritchard; Ann M Saunders; Perry C Gaskell; Gary W Small; P M Conneally; B Rosi; LH Yamaoka; Allen D Roses; Jonathan L Haines; Margaret Pericak-Vance
No association between very low density lipoprotein receptor (VLDL-R) and Alzheimer disease in American Caucasians.
Neuroscience letters 1996;209(2):105-8.
1996: William Scott; John H Growdon; Allen D Roses; Jonathan L Haines; Margaret Pericak-Vance
Presenilin-1 polymorphism and Alzheimer's disease.
Lancet 1996;347(9009):1186-7.
1996: Jonathan L Haines; M L Pritchard; Ann M Saunders; J M Schildkraut; John H Growdon; Perry C Gaskell; Lindsay A Farrer; S A Auerbach; James Gusella; P A Locke; B L Rosi; LH Yamaoka; Gary W Small; P M Conneally; Allen D Roses; Margaret Pericak-Vance
No genetic effect of alpha1-antichymotrypsin in Alzheimer disease.
Genomics 1996;33(1):53-6.
1996: Fong-Fong Chu; H A Rohan de Silva; R Steven Esworthy; K K Boteva; C E Walters; Allen D Roses; P N Rao; M J Pettenati
Polymorphism and chromosomal localization of the GI-form of human glutathione peroxidase (GPX2) on 14q24.1 by in situ hybridization.
Genomics 1996;32(2):272-6.
1996: James R Burke; J J Enghild; M E Martin; Y S Jou; Richard Myers; Allen D Roses; Jeffery Vance; Warren J Strittmatter
Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.
Nature medicine 1996;2(3):347-50.
1996: Allen D Roses
From genes to mechanisms to therapies: lessons to be learned from neurological disorders.
Nature medicine 1996;2(3):267-9.
1996: E H Corder; Allen D Roses
No increased risk of the apolipoprotein E epsilon2 allele with early-onset Alzheimer's disease.
Annals of neurology 1996;39(3):414-6.
1996: Carol F Lippa; Ann M Saunders; T W Smith; Joan M Swearer; David Drachman; Bernardino Ghetti; Linda E Nee; D Pulaski-Salo; dennis dickson; Y Robitaille; C Bergeron; Barbara J Crain; M D Benson; Martin R Farlow; Bradley T Hyman; S P George-Hyslop; Allen D Roses; Daniel A Pollen
Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway.
Neurology 1996;46(2):406-12.
1996: Allen D Roses; Gillian Einstein; John Gilbert; Michel Goedert; S H Han; D Huang; Christine M Hulette; Eliezer Masliah; Margaret Pericak-Vance; Ann M Saunders; Donald E Schmechel; Warren J Strittmatter; Karl H Weisgraber; P T Xi
Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism.
Annals of the New York Academy of Sciences 1996;777():146-57.
1996: B Meckelein; H A de Silva; Allen D Roses; P N Rao; M J Pettenati; P T Xu; R Hodge; M J Glucksman; Carmela Abraham
Human endopeptidase (THOP1) is localized on chromosome 19 within the linkage region for the late-onset alzheimer disease AD2 locus.
Genomics 1996;31(2):246-9.
1996: Warren J Strittmatter; James R Burke; V S DeSerrano; D Y Huang; William D. Matthew; Ann M Saunders; B L Scott; Jeffery Vance; Karl H Weisgraber; Allen D Roses
Protein: protein interactions in Alzheimer's disease and the CAG triplet repeat diseases.
Cold Spring Harbor symposia on quantitative biology 1996;61():597-605.
1996: C Constantinou Deltas; E Bashiardes; Philippos C Patsalis; M Hadjimarcou; P M Kroisel; P A Ioannou; Allen D Roses; J E Lee
Complete coding sequence, exon/intron arrangement and chromosome location of ZNF45, a KRAB-domain-containing gene.
Cytogenetics and cell genetics 1996;75(4):230-3.
1996: Pu-Ting Xu; Donald E Schmechel; T Rothrock-Christian; D S Burkhart; H L Qiu; Brian Popko; Patrick M. Sullivan; Nobuyo Maeda; Ann M Saunders; Allen D Roses; John Gilbert
Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.
Neurobiology of disease 1996;3(3):229-45.
1996: Warren J Strittmatter; Allen D Roses
Apolipoprotein E and Alzheimer's disease.
Annual review of neuroscience 1996;19():53-77.
1996: Allen D Roses
Apolipoprotein E alleles as risk factors in Alzheimer's disease.
Annual review of medicine 1996;47():387-400.
1995: A Kumar; R S Kandt; Chantelle M Wolpert; Allen D Roses; Margaret Pericak-Vance; John Gilbert
Mutation analysis of the TSC2 gene in an African-American family.
Human molecular genetics 1995;4(12):2295-8.
1995: Eliezer Masliah; Margaret Mallory; N Ge; Michael Alford; isaac veinbergs; Allen D Roses
Neurodegeneration in the central nervous system of apoE-deficient mice.
Experimental neurology 1995;136(2):107-22.
1995: Carmelo Graffagnino; Michael H Herbstreith; Donald E Schmechel; Efrat Levy; Allen D Roses; Mark J Alberts
Cystatin C mutation in an elderly man with sporadic amyloid angiopathy and intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 1995;26(11):2190-3.
1995: K Ben Othmane; M C Speer; J Stauffer; S Blel; Lefkos T Middleton; Christiane Ben Hamida; A Etribi; D Loeb; Faycal Hentati; Allen D Roses
Evidence for linkage disequilibrium in chromosome 13-linked Duchenne-like muscular dystrophy (LGMD2C)
American journal of human genetics 1995;57(3):732-4.
1995: M J Alberts; Carmelo Graffagnino; C McClenny; D DeLong; Warren J Strittmatter; Ann M Saunders; Allen D Roses
ApoE genotype and survival from intracerebral haemorrhage.
Lancet 1995;346(8974):575.
1995: A Kumar; Chantelle M Wolpert; R S Kandt; J Segal; J Pufky; Allen D Roses; Margaret Pericak-Vance; John Gilbert
A de novo frame-shift mutation in the tuberin gene.
Human molecular genetics 1995;4(8):1471-2.
1995: K B Othmane; D Loeb; R Hayworth-Hodgte; Faycal Hentati; N Rao; Allen D Roses; Mongi Ben Hamida; Margaret Pericak-Vance; Jeffery Vance
Physical and genetic mapping of the CMT4A locus and exclusion of PMP-2 as the defect in CMT4A.
Genomics 1995;28(2):286-90.
1995: John C S Breitner; K A Welsh; Michael J Helms; Perry C Gaskell; B A Gau; Allen D Roses; Margaret Pericak-Vance; Ann M Saunders
Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs.
Neurobiology of aging 1995;16(4):523-30.
1995: E H Corder; Ann M Saunders; Margaret Pericak-Vance; Allen D Roses
There is a pathologic relationship between ApoE-epsilon 4 and Alzheimer's disease.
Archives of neurology 1995;52(7):650-1.
1995: Allen D Roses
Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease.
Annals of neurology 1995;38(1):6-14.
1995: Allen D Roses; Ann M Saunders
Head injury, amyloid beta and Alzheimer's disease.
Nature medicine 1995;1(7):603-4.
1995: R Sherrington; Evgeny I Rogaev; Yan Liang; Ekaterina Rogaeva; Georges Levesque; Masaki Ikeda; H Chi; C Lin; G Li; K Holman; T Tsuda; L Mar; J F Foncin; A C Bruni; M P Montesi; Sandro Sorbi; I Rainero; L Pinessi; L Nee; I Chumakov; D Pollen; A Brookes; P Sanseau; R J Polinsky; W Wasco; H A Da Silva; J L Haines; M A Perkicak-Vance; Rudolph E Tanzi; Allen D Roses; Paul E Fraser; J M Rommens; Peter St George-Hyslop
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.
Nature 1995;375(6534):754-60.
1995: David Y Huang; Karl H Weisgraber; Michel Goedert; Ann M Saunders; Allen D Roses; Warren J Strittmatter
ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation.
Neuroscience letters 1995;192(3):209-12.
1995: Warren J Strittmatter; Allen D Roses
Apolipoprotein E and Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4725-7.
1995: John Mounsey; P Xu; J Edward John; L T Horne; John Gilbert; Allen D Roses; J Randall Moorman
Modulation of skeletal muscle sodium channels by human myotonin protein kinase.
The Journal of clinical investigation 1995;95(5):2379-84.
1995: Mark J Alberts; A QUINONES-HINOJOSA; Carmelo Graffagnino; A Friedman; Allen D Roses
Risk of intracranial aneurysms in families with subarachnoid hemorrhage.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1995;22(2):121-5.
1995: Allen D Roses
On the metabolism of apolipoprotein E and the Alzheimer diseases.
Experimental neurology 1995;132(2):149-56.
1995: X Chen; H A de Silva; M J Pettenati; P N Rao; Peter St George-Hyslop; Allen D Roses; Y Xia; K Horsburgh; K Uéda; T Saitoh
The human NACP/alpha-synuclein gene: chromosome assignment to 4q21.3-q22 and TaqI RFLP analysis.
Genomics 1995;26(2):425-7.
1995: Allen D Roses; Ann M Saunders; Elizabeth H Corder; Margaret Pericak-Vance; S H Han; Gillian Einstein; Christine M Hulette; Donald E Schmechel; M Holsti; David Y Huang
Influence of the susceptibility genes apolipoprotein E-epsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease.
Arzneimittel-Forschung 1995;45(3A):413-7.
1995: Allen D Roses; Ann M Saunders; M A Alberts; Warren J Strittmatter; Donald E Schmechel; E Gorder; Margaret Pericak-Vance
Apolipoprotein E E4 allele and risk of dementia.
JAMA : the journal of the American Medical Association 1995;273(5):374-5; author reply 375-6.
1995: Elizabeth H Corder; Ann M Saunders; Warren J Strittmatter; Donald E Schmechel; Perry C Gaskell; Allen D Roses; Margaret Pericak-Vance; Gary W Small; Jonathan L Haines
The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease.
JAMA : the journal of the American Medical Association 1995;273(5):373-4.
1995: Allen D Roses; Ann M Saunders; Warren J Strittmatter; Donald E Schmechel; Margaret Pericak-Vance; Bradley T Hyman
Apolipoprotein E in Creutzfeldt-Jacob disease.
Lancet 1995;345(8941):69.
1995: Carol F Lippa; T W Smith; Ann M Saunders; R Crook; D Pulaski-Salo; Peter Davies; John Hardy; Allen D Roses; dennis dickson
Apolipoprotein E genotype and Lewy body disease.
Neurology 1995;45(1):97-103.
1994: Allen D Roses; Ann M Saunders
APOE is a major susceptibility gene for Alzheimer's disease.
Current opinion in biotechnology 1994;5(6):663-7.
1994: David Y Huang; Michel Goedert; R Jakes; Karl H Weisgraber; C C Garner; Ann M Saunders; Margaret Pericak-Vance; Donald E Schmechel; Allen D Roses; Warren J Strittmatter
Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease.
Neuroscience letters 1994;182(1):55-8.
1994: Warren J Strittmatter; Ann M Saunders; Michel Goedert; Karl H Weisgraber; L M Dong; R Jakes; David Y Huang; Margaret Pericak-Vance; Donald E Schmechel; Allen D Roses
Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):11183-6.
1994: Michel Goedert; Warren J Strittmatter; Allen D Roses
Alzheimer's disease. Risky apolipoprotein in brain.
Nature 1994;372(6501):45-6.
1994: Thomas G Jensen; Allen D Roses; Arne Lund Jørgensen
Apolipoprotein E uptake and degradation via chloroquine-sensitive pathway in cultivated monkey cells overexpressing low density lipoprotein receptor.
Neuroscience letters 1994;180(2):193-6.
1994: Carmelo Graffagnino; Michael H Herbstreith; Allen D Roses; Mark J Alberts
A molecular genetic study of intracerebral hemorrhage.
Archives of neurology 1994;51(10):981-4.
1994: S H Han; Gillian Einstein; Karl H Weisgraber; Warren J Strittmatter; Ann M Saunders; Margaret Pericak-Vance; Allen D Roses; Donald E Schmechel
Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study.
Journal of neuropathology and experimental neurology 1994;53(5):535-44.
1994: Allen D Roses
Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease.
Journal of neuropathology and experimental neurology 1994;53(5):429-37.
1994: LH Yamaoka; Carol A Westbrook; Marcy C Speer; JM Gilchrist; Ethylin Jabs; E G Schweins; Jeffrey M Stajich; Perry C Gaskell; Allen D Roses; Margaret Pericak-Vance
Development of a microsatellite genetic map spanning 5q31-q33 and subsequent placement of the LGMD1A locus between D5S178 and IL9.
Neuromuscular disorders : NMD 1994;4(5-6):471-5.
1994: Jan Näslund; A Schierhorn; U Hellman; Lars Lannfelt; Allen D Roses; Lars O Tjernberg; J Silberring; Sam Gandy; Bengt Winblad; Paul Greengard
Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8378-82.
1994: David A Sanan; Karl H Weisgraber; S J Russell; Robert W Mahley; D Huang; Ann M Saunders; Donald E Schmechel; Thomas Wisniewski; Blas Frangione; Allen D Roses
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.
The Journal of clinical investigation 1994;94(2):860-9.
1994: James R Burke; M S Wingfield; K E Lewis; Allen D Roses; J E Lee; C Hulette; Margaret Pericak-Vance; Jeffery Vance
The Haw River syndrome: dentatorubropallidoluysian atrophy (DRPLA) in an African-American family.
Nature genetics 1994;7(4):521-4.
1994: S H Han; Christine M Hulette; Ann M Saunders; Gillian Einstein; Margaret Pericak-Vance; Warren J Strittmatter; Allen D Roses; Donald E Schmechel
Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls.
Experimental neurology 1994;128(1):13-26.
1994: Allen D Roses; Warren J Strittmatter; Margaret Pericak-Vance; Elizabeth H Corder; Ann M Saunders; Donald E Schmechel
Clinical application of apolipoprotein E genotyping to Alzheimer's disease.
Lancet 1994;343(8912):1564-5.
1994: Allen D Roses
Muscle biochemistry and a genetic study of myotonic dystrophy.
Science (New York, N.Y.) 1994;264(5158):587-8.
1994: M L Peacock; Daniel L Murman; Anders A F Sima; James T Warren; Allen D Roses; John K Fink
Novel amyloid precursor protein gene mutation (codon 665Asp) in a patient with late-onset Alzheimer's disease.
Annals of neurology 1994;35(4):432-8.
1994: Karl H Weisgraber; Allen D Roses; Warren J Strittmatter
The role of apolipoprotein E in the nervous system.
Current opinion in lipidology 1994;5(2):110-6.
1994: F Samson; L Mesnard; M Mihovilovic; T G Potter; Jean-Jacques Mercadier; Allen D Roses; John Gilbert
A new human slow skeletal troponin T (TnTs) mRNA isoform derived from alternative splicing of a single gene.
Biochemical and biophysical research communications 1994;199(2):841-7.
1994: Allen D Roses
Hereditary components in the neurodegerative diseases: Alzheimer's disease and myotonic dystrophy.
Neurobiology of aging 1994;15(2):243-5.
1994: Allen D Roses; Margaret Pericak-Vance; Ann M Saunders; Donald E Schmechel; Dmitry Goldgaber; Warren J Strittmatter
Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy?
Epilepsia 1994;35 Suppl 1():S20-8.
1994: John K Fink; M L Peacock; James T Warren; Allen D Roses; Stanley B Prusiner
Detecting prion protein gene mutations by denaturing gradient gel electrophoresis.
Human mutation 1994;4(1):42-50.
1994: Allen D Roses
Apolipoprotein E is a relevant susceptibility gene that affects the rate of expression of Alzheimer's disease.
Neurobiology of aging 1994;15 Suppl 2():S165-7.
1993: Juris J Liepnieks; Bernardino Ghetti; Martin R Farlow; Allen D Roses; Merrill D Benson
Characterization of amyloid fibril beta-peptide in familial Alzheimer's disease with APP717 mutations.
Biochemical and biophysical research communications 1993;197(2):386-92.
1993: Mirta Mihovilovic; Allen D Roses
Expression of alpha-3, alpha-5, and beta-4 neuronal acetylcholine receptor subunit transcripts in normal and myasthenia gravis thymus. Identification of thymocytes expressing the alpha-3 transcripts.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(11):6517-24.
1993: Melanie Haas Kucherlapati; David C Ward; J Lee; Allen D Roses; V Clarke; P D'Eustachio; D Lau; Eleazar Vega-Saenz de Miera; Bernardo Rudy
Localization of Shaw-related K+ channel genes on mouse and human chromosomes.
Mammalian genome : official journal of the International Mammalian Genome Society 1993;4(12):711-5.
1993: K W Small; J Weber; Allen D Roses; P Pericak-Vance
North Carolina macular dystrophy (MCDR1). A review and refined mapping to 6q14-q16.2.
Ophthalmic paediatrics and genetics 1993;14(4):143-50.
1993: Mirta Mihovilovic; Y Mai; Michael H Herbstreith; F Rubboli; paola Tarroni; Francesco Clementi; Allen D Roses
Splicing of an anti-sense Alu sequence generates a coding sequence variant for the alpha-3 subunit of a neuronal acetylcholine receptor.
Biochemical and biophysical research communications 1993;197(1):137-44.
1993: David Y Huang; M Martin; D Hu; Allen D Roses; Dmitry Goldgaber; Warren J Strittmatter
Binding of IgG to amyloid beta A4 peptide via the heavy-chain hinge region with preservation of antigen binding.
Journal of neuroimmunology 1993;48(2):199-203.
1993: Donald E Schmechel; Ann M Saunders; Warren J Strittmatter; Barbara J Crain; Christine M Hulette; S H Joo; Margaret Pericak-Vance; Dmitry Goldgaber; Allen D Roses
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9649-53.
1993: K Ben Othmane; Faycal Hentati; F Lennon; Christiane Ben Hamida; S Blel; Allen D Roses; Margaret Pericak-Vance; Mongi Ben Hamida; Jeffery Vance
Linkage of a locus (CMT4A) for autosomal recessive Charcot-Marie-Tooth disease to chromosome 8q.
Human molecular genetics 1993;2(10):1625-8.
1993: Dmitry Goldgaber; A I Schwarzman; R Bhasin; Luisa Gregori; Donald E Schmechel; Ann M Saunders; Allen D Roses; Warren J Strittmatter
Sequestration of amyloid beta-peptide.
Annals of the New York Academy of Sciences 1993;695():139-43.
1993: Warren J Strittmatter; Karl H Weisgraber; David Y Huang; L M Dong; Guy S Salvesen; Margaret Pericak-Vance; Donald E Schmechel; Ann M Saunders; Dmitry Goldgaber; Allen D Roses
Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):8098-102.
1993: Ann M Saunders; Allen D Roses
Apolipoprotein E4 allele frequency, ischemic cerebrovascular disease, and Alzheimer's disease.
Stroke; a journal of cerebral circulation 1993;24(9):1416-7.
1993: Elizabeth H Corder; Ann M Saunders; Warren J Strittmatter; Donald E Schmechel; Perry C Gaskell; Gary W Small; Allen D Roses; Jonathan L Haines; Margaret Pericak-Vance
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
Science (New York, N.Y.) 1993;261(5123):921-3.
1993: K Ben Othmane; Lefkos T Middleton; L J Loprest; K M Wilkinson; F Lennon; M P Rozear; Jeffrey M Stajich; Perry C Gaskell; Allen D Roses; Margaret Pericak-Vance
Localization of a gene (CMT2A) for autosomal dominant Charcot-Marie-Tooth disease type 2 to chromosome 1p and evidence of genetic heterogeneity.
Genomics 1993;17(2):370-5.
1993: Warren J Strittmatter; David Y Huang; R Bhasin; Allen D Roses; Dmitry Goldgaber
Avid binding of beta A amyloid peptide to its own precursor.
Experimental neurology 1993;122(2):327-34.
1993: Kenneth L Phillips; D M Gartrell; Allen D Roses; J E Lee
A triplet repeat polymorphism in a gene expressed in human hypothalamus.
Human molecular genetics 1993;2(8):1332.
1993: Mirta Mihovilovic; Christine M Hulette; J Mittelstaedt; C Austin; Allen D Roses
Nicotinic neuronal acetylcholine receptor alpha-3 subunit transcription in normal and myasthenic thymus.
Annals of the New York Academy of Sciences 1993;681():83-96.
1993: M L Peacock; James T Warren; Allen D Roses; John K Fink
Novel polymorphism in the A4 region of the amyloid precursor protein gene in a patient without Alzheimer's disease.
Neurology 1993;43(6):1254-6.
1993: S R Zeldenrust; J Murrell; Martin R Farlow; Bernardino Ghetti; Allen D Roses; Merrill D Benson
RFLP analysis for APP 717 mutations associated with Alzheimer's disease.
Journal of medical genetics 1993;30(6):476-8.
1993: Warren J Strittmatter; Ann M Saunders; Donald E Schmechel; Margaret Pericak-Vance; Jan J Enghild; Guy S Salvesen; Allen D Roses
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1977-81.
1993: Allen D Roses
Molecular genetics of neurodegenerative diseases.
Current opinion in neurology and neurosurgery 1993;6(1):34-9.
1993: Margaret Pericak-Vance; Peter St George-Hyslop; Perry C Gaskell; John H Growdon; Barbara J Crain; Christine M Hulette; James Gusella; LH Yamaoka; Rudolph E Tanzi; Allen D Roses
Linkage analysis in familial Alzheimer disease: description of the Duke and Boston data sets.
Genetic epidemiology 1993;10(6):361-4.
1992: Allen D Roses
Conflicts of interest.
Science (New York, N.Y.) 1992;258(5089):1717.
1992: Peter St George-Hyslop; Jonathan L Haines; Evgeny I Rogaev; M Mortilla; Giovanna Vaula; Margaret Pericak-Vance; J F Foncin; M Montesi; A Bruni; Sandro Sorbi; I Rainero; L Pinessi; D Pollen; R Polinsky; L Nee; J Kennedy; F Macciardi; E Rogaeva; Y Liang; N Alexandrova; W Lukiw; K Schlumpf; Rudolph E Tanzi; T Tsuda; L Farrer; J M Cantu; Ranjan Duara; L Amaducci; L Bergamini; James Gusella; Allen D Roses; D Crapper McLachlan
Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14.
Nature genetics 1992;2(4):330-4.
1992: K Ben Othmane; Mongi Ben Hamida; Margaret Pericak-Vance; Christiane Ben Hamida; S Blel; S C Carter; A M Bowcock; K Petruhkin; T C Gilliam; Allen D Roses
Linkage of Tunisian autosomal recessive Duchenne-like muscular dystrophy to the pericentromeric region of chromosome 13q.
Nature genetics 1992;2(4):315-7.
1992: Mark J Alberts; P Ioannou; R Deucher; John Gilbert; J Lee; L Middleton; Allen D Roses
Isolation of a cytochrome oxidase gene overexpressed in Alzheimer's disease brain.
Molecular and cellular neurosciences 1992;3(5):461-70.
1992: Kenneth L Phillips; J H Garbutt; Allen D Roses; J E Lee
A chromosome 19 CA-dinucleotide repeat polymorphism.
Human molecular genetics 1992;1(7):551.
1992: John Gilbert; Jeffrey M Stajich; Marcy C Speer; Jeffery Vance; C S Stewart; LH Yamaoka; F Samson; M Fardeau; T G Potter; Allen D Roses
Linkage studies in facioscapulohumeral muscular dystrophy (FSHD).
American journal of human genetics 1992;51(2):424-7.
1992: F Samson; P J de Jong; B J Trask; P Koza-Taylor; Marcy C Speer; T Potter; Allen D Roses; John Gilbert
Assignment of the human slow skeletal troponin T gene to 19q13.4 using somatic cell hybrids and fluorescence in situ hybridization analysis.
Genomics 1992;13(4):1374-5.
1992: M Pröschel; Ann M Saunders; Allen D Roses; C R Müller
Dinucleotide repeat polymorphism at the human gene for the brain-derived neurotrophic factor (BDNF).
Human molecular genetics 1992;1(5):353.
1992: Kent W Small; J L Weber; Allen D Roses; F Lennon; Jeffery Vance; Margaret Pericak-Vance
North Carolina macular dystrophy is assigned to chromosome 6.
Genomics 1992;13(3):681-5.
1992: C Pritchard; N Zhu; J Zuo; Laura N Bull; Margaret Pericak-Vance; Jeffery Vance; Allen D Roses; A Milatovich; U Francke; D R Cox
Recombination of 4p16 DNA markers in an unusual family with Huntington disease.
American journal of human genetics 1992;50(6):1218-30.
1992: Nicholas J H Sharp; Joe Kornegay; Sandy Van Camp; Michael H Herbstreith; S L Secore; S Kettle; Wu-Yen Hung; C D Constantinou; Michael J Dykstra; Allen D Roses
An error in dystrophin mRNA processing in golden retriever muscular dystrophy, an animal homologue of Duchenne muscular dystrophy.
Genomics 1992;13(1):115-21.
1992: A Kazantsev; LH Yamaoka; Allen D Roses
A dinucleotide repeat polymorphism in the human Na+,K+ ATPase, alpha subunit (ATP1A3) gene.
Nucleic acids research 1992;20(5):1164.
1992: C D Constantinou-Deltas; John Gilbert; R J Bartlett; Michael H Herbstreith; Allen D Roses; J E Lee
The identification and characterization of KRAB-domain-containing zinc finger proteins.
Genomics 1992;12(3):581-9.
1992: L J Loprest; Margaret Pericak-Vance; Jeffrey M Stajich; Perry C Gaskell; A M Lucas; F Lennon; LH Yamaoka; Allen D Roses; Jeffery Vance
Linkage studies in Charcot-Marie-Tooth disease type 2: evidence that CMT types 1 and 2 are distinct genetic entities.
Neurology 1992;42(3 Pt 1):597-601.
1992: Allen D Roses; M Alberts; Warren J Strittmatter
Alzheimer's disease - reassessing the data.
Current biology : CB 1992;2(1):7-9.
1991: F Samson; John Gilbert; P Koza-Taylor; Marcy C Speer; J Lee; Allen D Roses
A PstI polymorphism detected by a genomic clone at the human slow troponin T (TNNT1) gene locus.
Nucleic acids research 1991;19(21):6058.
1991: Kent W Small; J L Weber; Wu-Yen Hung; Jeffery Vance; Allen D Roses; Margaret Pericak-Vance
North Carolina macular dystrophy: exclusion map using RFLPs and microsatellites.
Genomics 1991;11(3):763-6.
1991: A M Lucas; Jeffery Vance; Jeffrey M Stajich; Allen D Roses
A PvuII polymorphism detected by pEW404 (D17S64) on chromosome 17.
Nucleic acids research 1991;19(20):5802.
1991: Gerard D Schellenberg; L Anderson; S O'dahl; E M Wisjman; A D Sadovnick; Melvyn Ball; Eric B Larson; Walter A Kukull; George M Martin; Allen D Roses
APP717, APP693, and PRIP gene mutations are rare in Alzheimer disease.
American journal of human genetics 1991;49(3):511-7.
1991: Donald Goodkin; T H Doolittle; S S Hauser; R M Ransohoff; Allen D Roses; R A Rudick
Diagnostic criteria for multiple sclerosis research involving multiply affected families.
Archives of neurology 1991;48(8):805-7.
1991: Mark J Alberts; Margaret Pericak-Vance; V Royal; J Bebout; Perry C Gaskell; J Thomas; Wu-Yen Hung; C Clark; N Earl; Allen D Roses
Genetic linkage analysis of nerve growth factor (beta) in familial Alzheimer's disease.
Annals of neurology 1991;30(2):216-9.
1991: V Royal; Mark J Alberts; Margaret Pericak-Vance; G Finocchiaro; J Bebout; LH Yamaoka; Wu-Yen Hung; Perry C Gaskell; Allen D Roses
RsaI RFLP for electron transport flavoprotein-beta(ETFB).
Nucleic acids research 1991;19(14):4021.
1991: Allen D Roses; P M Conneally
Alzheimer's disease cell bank.
Science (New York, N.Y.) 1991;252(5002):14.
1991: Jeffery Vance; D Barker; LH Yamaoka; Jeffrey M Stajich; L Loprest; Wu-Yen Hung; Kenneth H Fischbeck; Allen D Roses; Margaret Pericak-Vance
Localization of Charcot-Marie-Tooth disease type 1a (CMT1A) to chromosome 17p11.2.
Genomics 1991;9(4):623-8.
1991: Mark J Alberts; R S Kandt; Margaret Pericak-Vance; J Bebout; Marcy C Speer; Teepu Siddique; LH Yamaoka; Wu-Yen Hung; Perry C Gaskell; Allen D Roses
MspI RFLP for microtubule associated protein-2 (MAP2).
Nucleic acids research 1991;19(4):960.
1991: Mirta Mihovilovic; Allen D Roses
Expression of mRNAs in human thymus coding for the alpha 3 subunit of a neuronal acetylcholine receptor.
Experimental neurology 1991;111(2):175-80.
1991: Marcy C Speer; Dmitry Goldgaber; Lev G Goldfarb; Allen D Roses; Margaret Pericak-Vance
Support of linkage of Gerstmann-Sträussler-Scheinker syndrome to the prion protein gene on chromosome 20p12-pter.
Genomics 1991;9(2):366-8.
1991: James R Burke; Allen D Roses
Genetics of Alzheimer's disease.
International journal of neurology 1991;25-26():41-51.
1991: R S Kandt; Margaret Pericak-Vance; Wu-Yen Hung; R J Gardner; P E Crossen; M D Nellist; Marcy C Speer; Allen D Roses
Linkage studies in tuberous sclerosis. Chromosome 9?, 11?, or maybe 14!
Annals of the New York Academy of Sciences 1991;615():284-97.
1990: F Samson; J E Lee; Wu-Yen Hung; T G Potter; Michael H Herbstreith; Allen D Roses; John Gilbert
Isolation and localization of a slow troponin (TnT) gene on chromosome 19 by subtraction hybridization of a cDNA muscle library using myotonic dystrophy muscle cDNA.
Journal of neuroscience research 1990;27(4):441-51.
1990: Marcy C Speer; Margaret Pericak-Vance; LH Yamaoka; Wu-Yen Hung; A Ashley; Jeffrey M Stajich; Allen D Roses
Presymptomatic and prenatal diagnosis in myotonic dystrophy by genetic linkage studies.
Neurology 1990;40(4):671-6.
1990: Jeffery Vance; Kent W Small; M A Jones; Jeffrey M Stajich; LH Yamaoka; Allen D Roses; Wu-Yen Hung; Margaret Pericak-Vance
Confirmation of linkage in von Hippel-Lindau disease.
Genomics 1990;6(3):565-7.
1990: Allen D Roses; Margaret Pericak-Vance; C M Clark; John Gilbert; LH Yamaoka; CS Haynes; Marcy C Speer; Perry C Gaskell; Wu-Yen Hung; J A Trofatter
Linkage studies of late-onset familial Alzheimer's disease.
Advances in neurology 1990;51():185-96.
1990: Joe Kornegay; Nicholas J H Sharp; R J Bartlett; Sandy Van Camp; C T Burt; Wu-Yen Hung; Lester Kwock; Allen D Roses
Golden retriever muscular dystrophy: monitoring for success.
Advances in experimental medicine and biology 1990;280():267-72.
1990: R J Bartlett; Nicholas J H Sharp; Wu-Yen Hung; Joe Kornegay; Allen D Roses
Molecular markers for myoblast transplantation in GRMD.
Advances in experimental medicine and biology 1990;280():273-8.
1989: J E Lee; J H Garbutt; J Pufky; C Ciccone; A Walker; R Bartlett; Allen D Roses
A polymorphic DNA sequence (174-3.7) on chromosome 19 [D19S58].
Nucleic acids research 1989;17(23):10144.
1989: Allen D Roses
A conservative viewpoint on linkage in Alzheimer's disease.
Neurobiology of aging 1989;10(5):427-9; discussion 446-8.
1989: Teepu Siddique; H Roper; Margaret Pericak-Vance; J Shaw; K L Warner; Wu-Yen Hung; Kenneth L Phillips; PW Lunt; W J Cumming; Allen D Roses
Linkage analysis in the spinal muscular atrophy type of facioscapulohumeral disease.
Journal of medical genetics 1989;26(8):487-9.
1989: Nigel G Laing; Teepu Siddique; R Bartlett; LH Yamaoka; Wu-Yen Hung; Margaret Pericak-Vance; Allen D Roses
Duchenne muscular dystrophy: detection of deletion carriers by spectrophotometric densitometry.
Clinical genetics 1989;35(6):393-8.
1989: Jeffery Vance; G A Nicholson; LH Yamaoka; Jeffrey M Stajich; C S Stewart; Marcy C Speer; Wu-Yen Hung; Allen D Roses; D Barker; Margaret Pericak-Vance
Linkage of Charcot-Marie-Tooth neuropathy type 1a to chromosome 17.
Experimental neurology 1989;104(2):186-9.
1989: Teepu Siddique; K Phillips; Heinrich Betz; G Grenningloh; K Warner; Wu-Yen Hung; Nigel G Laing; Allen D Roses
RFLPs of the gene for the human glycine receptor on the X-chromosome.
Nucleic acids research 1989;17(4):1785.
1989: Mark J Alberts; Allen D Roses
Myotonic muscular dystrophy.
Neurologic clinics 1989;7(1):1-8.
1989: Deborah V Dawson; Allen D Roses; Margaret Pericak-Vance; E B Kaplan; R C Elston; CS Haynes; Perry C Gaskell; Albert Heyman; C M Clark; N L Earl
Sib-pair linkage analysis in late onset Alzheimer's disease.
Progress in clinical and biological research 1989;317():223-8.
1989: Allen D Roses; Margaret Pericak-Vance; LH Yamaoka; CS Haynes; M Speer; Perry C Gaskell; Wu-Yen Hung; C M Clark; Albert Heyman; J Trofatter
Linkage studies in familial Alzheimer's disease.
Progress in clinical and biological research 1989;317():201-15.
1988: keith jack johnson; E Nimmo; P Jones; M Weiss; Marja-Liisa Savontaus; M Anvret; R Bartlett; Allen D Roses; D Shaw; P S Harper
Segregation of linked probes to myotonic dystrophy in a family demonstrating that 152 and APOC2 are on the same side of DM on 19q.
Human genetics 1988;80(4):379-81.
1988: C S Payne; Allen D Roses
The molecular genetic revolution. Its impact on clinical neurology.
Archives of neurology 1988;45(12):1366-76.
1988: A P Walker; R J Bartlett; Nigel G Laing; Teepu Siddique; LH Yamaoka; J C Chen; Wu-Yen Hung; Allen D Roses
RFLP for Duchenne muscular dystrophy cDNA clone 30-2.
Nucleic acids research 1988;16(18):9072.
1988: A P Walker; R J Bartlett; LH Yamaoka; S L Secore; J E Lee; John Gilbert; Michael H Herbstreith; Margaret Pericak-Vance; Wu-Yen Hung; Allen D Roses
A Bgl II polymorphism detected by LDR152 [D19S19].
Nucleic acids research 1988;16(18):9063.
1988: Teepu Siddique; R McKinney; Wu-Yen Hung; R J Bartlett; G Bruns; T K Mohandas; H H Ropers; C Wilfert; Allen D Roses
The poliovirus sensitivity (PVS) gene is on chromosome 19q12----q13.2.
Genomics 1988;3(2):156-60.
1988: Nigel G Laing; Teepu Siddique; R J Bartlett; LH Yamaoka; J C Chen; A P Walker; Wu-Yen Hung; Allen D Roses
RFLP for Duchenne muscular dystrophy cDNA clone 44-1.
Nucleic acids research 1988;16(14B):7209.
1988: Marcy C Speer; Margaret Pericak-Vance; LH Yamaoka; James Koh; Wu-Yen Hung; Perry C Gaskell; Jeffery Vance; R J Bartlett; Allen D Roses
Prenatal diagnosis using deletion studies in Duchenne muscular dystrophy.
Prenatal diagnosis 1988;8(6):427-37.
1988: Allen D Roses
Mutants in Duchenne muscular dystrophy. Implications for prevention.
Archives of neurology 1988;45(1):84-5.
1988: JM Gilchrist; Margaret Pericak-Vance; L Silverman; Allen D Roses
Clinical and genetic investigation in autosomal dominant limb-girdle muscular dystrophy.
Neurology 1988;38(1):5-9.
1988: Donald E Schmechel; Dmitry Goldgaber; D S Burkhart; John Gilbert; D Carleton Gajdusek; Allen D Roses
Cellular localization of messenger RNA encoding amyloid-beta-protein in normal tissue and in Alzheimer disease.
Alzheimer disease and associated disorders 1988;2(2):96-111.
1988: Teepu Siddique; R Bartlett; Margaret Pericak-Vance; LH Yamaoka; James Koh; J Chen; Wu-Yen Hung; R Kandt; Allen D Roses
Update on the molecular genetics of Duchenne muscular dystrophy.
Australian paediatric journal 1988;24 Suppl 1():9-14.
1988: Allen D Roses; Margaret Pericak-Vance; R J Bartlett; LH Yamaoka; J E Lee; James Koh; J C Chen; John Gilbert; D A Ross; Michael H Herbstreith
Myotonic dystrophy: update on progress to define the gene.
Australian paediatric journal 1988;24 Suppl 1():66-9.
1987: Jeffery Vance; Margaret Pericak-Vance; M H Bowman; C S Payne; L Fredane; Teepu Siddique; Allen D Roses; E W Massey
Chorea-acanthocytosis: a report of three new families and implications for genetic counselling.
American journal of medical genetics 1987;28(2):403-10.
1987: M P Rozear; Margaret Pericak-Vance; Kenneth H Fischbeck; Jeffrey M Stajich; Perry C Gaskell; D A Krendel; D G Graham; D V Dawson; Allen D Roses
Hereditary motor and sensory neuropathy, X-linked: a half century follow-up.
Neurology 1987;37(9):1460-5.
1987: S R Diehl; Michael Boehnke; Francis S Collins; R P Erickson; I J Karolyi; L M Ploughman; Margaret Pericak-Vance; Arthur S Aylsworth; Allen D Roses
Linkage analysis of peripheral neurofibromatosis to DNA markers on chromosome 8.
Journal of medical genetics 1987;24(9):532-4.
1987: Margaret Pericak-Vance; LH Yamaoka; Jeffery Vance; Arthur S Aylsworth; G O Rossenwasser; Perry C Gaskell; Mark J Alberts; Wu-Yen Hung; CS Haynes; Allen D Roses
Linkage studies in peripheral neurofibromatosis.
Journal of medical genetics 1987;24(9):530-2.
1987: J T Lanman; Margaret Pericak-Vance; R J Bartlett; J C Chen; L Yamaoka; James Koh; Marcy C Speer; Wu-Yen Hung; Allen D Roses
Familial inheritance of a DXS164 deletion mutation from a heterozygous female.
American journal of human genetics 1987;41(2):138-44.
1987: Donald E Schmechel; P J Marangos; Brian M Martin; SL Winfield; D S Burkhart; Allen D Roses; Edward I Ginns
Localization of neuron-specific enolase (NSE) mRNA in human brain.
Neuroscience letters 1987;76(2):233-8.
1987: R C Griggs; J B Martin; A S Penn; Allen D Roses; J F Toole
Training clinical neuroscientists.
Annals of neurology 1987;21(2):197-201.
1987: Marcelle Morrison-Bogorad; S Pardue; K Maschoff; W S Griffin; Charles L White; John Gilbert; Allen D Roses
Brain messenger RNA levels and ribonuclease activity in Alzheimer's disease.
Biochemical Society transactions 1987;15(1):133-4.
1987: C Warren Olanow; A S Wechsler; M Sirotkin-Roses; Jeffrey M Stajich; Allen D Roses
Thymectomy as primary therapy in myasthenia gravis.
Annals of the New York Academy of Sciences 1987;505():595-606.
1986: Kenneth H Fischbeck; N ar-Rushdi; Margaret Pericak-Vance; M Rozear; Allen D Roses; J P Fryns
X-linked neuropathy: gene localization with DNA probes.
Annals of neurology 1986;20(4):527-32.
1986: Allen D Roses; Margaret Pericak-Vance; LH Yamaoka; Michael H Herbstreith; R J Bartlett; Teepu Siddique; Wu-Yen Hung; D A Ross; T K Mohandas; G Bruns
A new tightly linked DNA probe for myotonic dystrophy.
Neurology 1986;36(8):1146.
1986: Allen D Roses; Margaret Pericak-Vance; D A Ross; L Yamaoka; R J Bartlett
RFLPs at the D19S19 locus of human chromosome 19 linked to myotonic dystrophy (DM).
Nucleic acids research 1986;14(13):5569.
1986: Louis Kunkel; J Fielding Hejtmancik; C T Caskey; Astrid Speer; Anthony P Monaco; W Middlesworth; C A Colletti; C Bertelson; U Müller; M Bresnan; F Shapiro; U Tantravahi; J Speer; S A Latt; R Bartlett; Margaret Pericak-Vance; Allen D Roses; M W Thompson; P N Ray; R G Worton; Kenneth H Fischbeck; Pía Gallano; M Coulon; C Duros; J Boue; Claudine Junien; Jamel Chelly; G Hamard; Marc Jeanpierre; M Lambert; Jean-Claude Kaplan; A Emery; H Dorkins; S McGlade; Kay E Davies; Corinne D Boehm; B Arveiler; C Lemaire; G J Morgan; M J Denton; J Amos; Martin Bobrow; F Benham; E Boswinkel; C Cole; Victor Dubowitz; K Hart; S Hodgson; L Johnson; A Walker; L Roncuzzi; Alessandra Ferlini; C Nobile; Giovanni Romeo; D E Wilcox; N A Affara; M A Ferguson-Smith; M Lindolf; H Kaariainen; A de la Chapelle; V Ionasescu; Charles C Searby; R Ionasescu; Egbert Bakker; Gert-Jan B van Ommen; P L Pearson; Cheryl R Greenberg; J L Hamerton; Klaus Wrogemann; R A Doherty; R Polakowska; C Hyser; S Quirk; N Thomas; Jeffrey F Harper; B T Darras; U Francke
Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy.
Nature 1986;322(6074):73-7.
1986: G E Moore; Allen D Roses; Margaret Pericak-Vance; William Garrett Jr; F H Schachat
Promiscuous expression of myosin in myotonic dystrophy.
Muscle & nerve 1986;9(4):355-63.
1986: B Wainwright; NJ Lench; R Bartlett; Allen D Roses; R Williamson
RFLP identified by the anonymous DNA segment pBAM34 at 19q13.3-qter [HGM8 assignment D19S6].
Nucleic acids research 1986;14(7):3149.
1985: LH Yamaoka; R J Bartlett; D A Ross; G H Fey; David Ledbetter; G Bruns; Margaret Pericak-Vance; Michael H Herbstreith; Allen D Roses
Localization of cloned unique DNA to three different regions of chromosome 19: screen for linkage probes for myotonic dystrophy.
Journal of neurogenetics 1985;2(6):403-12.
1985: P Wong; A Barbeau; Allen D Roses
A method to quantitate Coomassie blue-stained proteins in cylindrical polyacrylamide gels.
Analytical biochemistry 1985;150(2):288-93.
1985: J R Moorman; R E Coleman; D L Packer; J A Kisslo; J Bell; B D Hettleman; J Stajich; Allen D Roses
Cardiac involvement in myotonic muscular dystrophy.
Medicine 1985;64(6):371-87.
1985: Anthony P Monaco; C J Bertelson; W Middlesworth; C A Colletti; J Aldridge; Kenneth H Fischbeck; R Bartlett; Margaret Pericak-Vance; Allen D Roses; Louis Kunkel
Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment.
Nature 1985;316(6031):842-5.
1985: Allen D Roses
Myotonic muscular dystrophy. From clinical description to molecular genetics.
Archives of internal medicine 1985;145(8):1487-92.
1985: P Wong; A Barbeau; Allen D Roses
Gel chromatography on a Sepharose 4B column: earlier elution of protein-sodium dodecyl sulfate complexes of low Stokes radii.
Analytical biochemistry 1985;146(1):191-8.
1984: C Warren Olanow; Allen D Roses
AChR antibody titer and clinical response to thymectomy in MG.
Neurology 1984;34(7):987-8.
1984: S J Greenberg; C Warren Olanow; D V Dawson; B Crane; Allen D Roses
Autologous mixed lymphocyte reaction in patients with myasthenia gravis: correlation with disease activity.
Journal of immunology (Baltimore, Md. : 1950) 1984;132(3):1229-36.
1984: C Warren Olanow; Allen D Roses
A new approach to late onset myasthenia gravis.
Geriatrics 1984;39(1):91-3, 97-9.
1984: L C Mokrasch; M Herbstreith; Allen D Roses
Vesicles with transport capability isolated from cultured fibroblasts.
Preparative biochemistry 1984;14(1):19-32.
1983: B F Haynes; E A Harden; C Warren Olanow; G S Eisenbarth; A S Wechsler; L L Hensley; Allen D Roses
Effect of thymectomy on peripheral lymphocyte subsets in myasthenia gravis: selective effect on T-cells in patients with thymic atrophy.
Journal of immunology (Baltimore, Md. : 1950) 1983;131(2):773-7.
1983: Allen D Roses; Margaret Pericak-Vance; LH Yamaoka; E Stubblefield; Jeffrey M Stajich; Jeffery Vance; M J Roses; D B Carter
Recombinant DNA strategies in genetic neurological diseases.
Muscle & nerve 1983;6(5):339-55.
1983: G B Hartwig; K R Rao; F M Radoff; R E Coleman; R H Jones; Allen D Roses
Radionuclide angiocardiographic analysis of myocardial function in myotonic muscular dystrophy.
Neurology 1983;33(5):657-60.
1983: P Hudgson; M W McAdams; Margaret Pericak-Vance; T M Edwards; Allen D Roses
Effect of sera from myasthenia gravis patients on acetylcholine receptors in myotube cultures.
Journal of the neurological sciences 1983;59(1):37-45.
1983: R J Lane; M Robinow; Allen D Roses
The genetic status of mothers of isolated cases of Duchenne muscular dystrophy.
Journal of medical genetics 1983;20(1):1-11.
1982: C Warren Olanow; A S Wechsler; Allen D Roses
A prospective study of thymectomy and serum acetylcholine receptor antibodies in myasthenia gravis.
Annals of surgery 1982;196(2):113-21.
1982: R L Wertz; Allen D Roses
Premature aging of fibroblasts from patients with Duchenne muscular dystrophy.
Pediatric research 1982;16(7):589-90.
1982: C Warren Olanow; R J Lane; K L Hull; Allen D Roses
Neonatal myasthenia gravis in the infant of an asymptomatic thymectomized mother.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1982;9(2):85-7.
1982: L H Yamaoka; Jeffery Vance; Allen D Roses
Myotonic muscular dystrophy. Calcium-dependent phosphatidate metabolism in the erythrocyte membrane.
Journal of the neurological sciences 1982;54(2):173-9.
1982: G B Hartwig; S E Miller; A P Frost; Allen D Roses
Myotonic muscular dystrophy: morphology, histochemistry, and growth characteristics of cultured skin fibroblasts.
Muscle & nerve 1982;5(2):125-30.
1982: C Warren Olanow; R J Lane; Allen D Roses
Thymectomy in late-onset myasthenia gravis.
Archives of neurology 1982;39(2):82-3.
1981: M E Mabry; Allen D Roses
Increased [32P]-phosphorylation of tryptic peptides of erythrocyte spectrin in Duchenne muscular dystrophy.
Muscle & nerve 1981;4(6):489-93.
1981: J Grey; H Gitelman; Allen D Roses
Comment on erythrocyte phospholipid metabolism in myotonic muscular dystrophy.
Annals of neurology 1981;10(5):494.
1981: Allen D Roses; P E Shile; M H Herbstreith; C V Balakrishnan
Identification of abnormally [32P]-phosphorylated cyanogen bromide cleavage product of erythrocyte membrane spectrin in Duchenne muscular dystrophy.
Neurology 1981;31(8):1026-30.
1981: C Warren Olanow; Allen D Roses
The pathogenesis of myasthenia gravis--a hypothesis.
Medical hypotheses 1981;7(7):957-68.
1981: R J Lane; Allen D Roses
Variation of serum creatine kinase levels with age in normal females: implications for genetic counselling in Duchenne muscular dystrophy.
Clinica chimica acta; international journal of clinical chemistry 1981;113(1):75-86.
1981: C Warren Olanow; Allen D Roses; J W Fay
The effect of plasmapheresis on post-thymectomy ocular dysfunction.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1981;8(2):169-72.
1981: R L Wertz; G B Hartwig; A P Frost; J J Brophy; S K Atwater; Allen D Roses
Patients with myotonic dystrophy, a possible segmental progeroid syndrome, and Duchenne muscular dystrophy have fibroblasts with normal limits for in vitro lifespan and growth characteristics.
Journal of cellular physiology 1981;107(2):255-60.
1981: G N Rizzo; C Warren Olanow; Allen D Roses
[Chorea in hyperparathyroidism. Report of a case].
AMB : revista da Associação Médica Brasileira 1981;27(5):155-6.
1981: Allen D Roses; C Warren Olanow; M W McAdams; R J Lane
No direct correlation between serum antiacetylcholine receptor antibody levels and clinical state of individual patients with myasthenia gravis.
Neurology 1981;31(2):220-4.
1981: Allen D Roses; P Hudgson; M W McAdams; A M Edwards; C Warren Olanow
On the mechanism of pathogenesis of human myasthenia gravis.
Transactions of the American Neurological Association 1981;106():212-5.
1980: Y Nagano; P Wong; Allen D Roses
Altered erythrocyte spectrin extractability in Duchenne muscular dystrophy.
Clinica chimica acta; international journal of clinical chemistry 1980;108(3):469-74.
1980: Y Nagano; Allen D Roses
Abnormalities of erythrocyte membranes in myotonic muscular dystrophy manifested in lipid vesicles.
Neurology 1980;30(9):989-91.
1980: M W McAdams; Allen D Roses
Comparison of antigenic sources for acetylcholine receptor antibody assays in myasthenia gravis.
Annals of neurology 1980;8(1):61-6.
1980: J E Grey; H J Gitelman; Allen D Roses
Myotonic muscular dystrophy: defective phospholipid metabolism in the erythrocyte plasma membrane.
The Journal of clinical investigation 1980;65(6):1478-82.
1980: R J Lane; D Gardner-Medwin; Allen D Roses
Electrocardiographic abnormalities in carriers of Duchenne muscular dystrophy.
Neurology 1980;30(5):497-501.
1980: Allen D Roses; G B Hartwig; M Mabry; Y Nagano; S E Miller
Red blood cell and fibroblast membranes in Duchenne and myotonic muscular dystrophy.
Muscle & nerve 1980;3(1):36-54.
1979: E N Prystowsky; E L Pritchett; Allen D Roses; J Gallagher
The natural history of conduction system disease in myotonic muscular dystrophy as determined by serial electrophysiologic studies.
Circulation 1979;60(6):1360-4.
1979: Allen D Roses; M J Roses; G A Nicholson; C R Roe
LDH-5 levels and electrophoresis support media.
Neurology 1979;29(10):1431-2.
1979: Allen D Roses
Erythrocyte membrane autophosphorylation in Duchenne muscular dystrophy: effect of two methods of erythrocyte ghost preparation on results.
Clinica chimica acta; international journal of clinical chemistry 1979;95(1):69-73.
1979: Allen D Roses
More on phosporylation of red-cell membranes in muscular dystrophy.
The New England journal of medicine 1979;300(19):1114.
1979: S DiMauro; G B Hartwig; A Hays; A B Eastwood; R Franco; M Olarte; M Chang; Allen D Roses; M Fetell; R S Schoenfeldt; L Z Stern
Debrancher deficiency: neuromuscular disorder in 5 adults.
Annals of neurology 1979;5(5):422-36.
1979: P Wong; Allen D Roses
Isolation of an abnormally phosphorylated erythrocyte membrane band 3 glycoprotein from patients with myotonic muscular dystrophy.
The Journal of membrane biology 1979;45(1-2):147-66.
1979: E N Prystowsky; E L Pritchett; John Gallagher; Allen D Roses
The natural history of cardiac conduction system disease in myotonic muscular dystrophy as determined by serial electrophysiology studies.
Transactions of the American Neurological Association 1979;104():18-21.
1978: J D Vickers; M P Rathbone; Allen D Roses
Alterations of erythrocyte ghost protein phosphorylation in the Duchenne and myotonic muscular dystrophies.
Biochemical medicine 1978;20(3):434-9.
1978: P Wong; Allen D Roses
Altered component a phosphorylation in erythrocyte membranes in myotonic muscular dystrophy.
Progress in clinical and biological research 1978;21():479-91.
1978: Allen D Roses; M H Herbstreith; B S Metcalf; G B Hartwig
Biochemical relationships between muscle and erythrocyte membrane. Interpretations with respect to Duchenne muscular dystrophy.
Electroencephalography and clinical neurophysiology. Supplement 1978;(34):463-8.
1977: Allen D Roses; M J Roses; B S Metcalf; K L Hull; G A Nicholson; G B Hartwig; C R Roe
Pedigree testing in Duchenne muscular dystrophy.
Annals of neurology 1977;2(4):271-8.
1977: Allen D Roses; G A Nicholson; C R Roe
Screening for Duchenne muscular dystrophy.
Pediatrics 1977;60(2):248-51.
1977: Allen D Roses; M J Roses; G A Nicholson; C R Roe
Lactate dehydrogenase isoenzyme in detecting carriers of Duchenne muscular dystrophy.
Neurology 1977;27(5):414-21.
1977: M S Roses; M T Nicholson; C S Kircher; Allen D Roses
Evaluation and detection of Duchenne's and Becker's muscular dystrophy carriers by manual muscle testing.
Neurology 1977;27(1):20-5.
1976: D Allan Butterfield; Allen D Roses; S H Appel; D B Chesnut
Electron spin resonance studies of membrane proteins in erythrocytes in myotonic muscular dystrophy.
Archives of biochemistry and biophysics 1976;177(1):226-34.
1976: Allen D Roses; M Herbstreith; B Metcalf; S H Appel
Increased phosphorylated components of erythrocyte membrane spectrin band II with reference to Duchenne muscular dystrophy.
Journal of the neurological sciences 1976;30(1):167-78.
1976: Allen D Roses; S H Appel
Erythrocyte spectrin peak II phosphorylation in Duchenne muscular dystrophy.
Journal of the neurological sciences 1976;29(2-4):185-93.
1976: Allen D Roses
Identification of Duchenne muscular dystrophy carriers.
Lancet 1976;2(7986):636.
1976: D Allan Butterfield; D B Chesnut; S H Appel; Allen D Roses
Spin label study of erythrocyte membrane fluidity in myotonic and Duchenne muscular dystrophy and congenital myotonia.
Nature 1976;263(5573):159-61.
1976: S E Miller; Allen D Roses; S H Appel
Scanning electron microscopy studies in muscular dystrophy.
Archives of neurology 1976;33(3):172-4.
1976: Allen D Roses; M J Roses; S E Miller; K L Hull; S H Appel
Carrier detection in Duchenne muscular dystrophy.
The New England journal of medicine 1976;294(4):193-8.
1976: Allen D Roses
Substrate heterogeneity of component a of the human erythrocyte membrane.
Journal of supramolecular structure 1976;4(4):481-6.
1976: K L Hull; Allen D Roses
Stoichiometry of sodium and potassium transport in erythrocytes from patients with myotonic muscular dystrophy.
The Journal of physiology 1976;254(1):169-81.
1975: Allen D Roses; D Allan Butterfield; S H Appel; D B Chestnut
Phenytoin and membrane fluidity in myotonic dystrophy.
Archives of neurology 1975;32(8):535-8.
1975: S E Miller; Allen D Roses; S H Appel
Letter: Erythrocytes in human muscular dystrophy.
Science (New York, N.Y.) 1975;188(4193):1131.
1975: Allen D Roses; M H Herbstreith; S H Appel
Membrane protein kinase alteration in Duchenne muscular dystrophy.
Nature 1975;254(5498):350-1.
1975: Allen D Roses; S H Appel; D Allan Butterfield; S E Miller; D B Chesnut
Specificity of biochemical and biophysical tests in Duchenne and myotonic muscular dystrophy, carrier states, and congenital myotonia.
Transactions of the American Neurological Association 1975;100():131-4.
1975: Allen D Roses; S H Appel
Phosphorylation of component a of the human erythrocyte membrane in myotonic muscular dystrophy.
The Journal of membrane biology 1975;20(1-2):51-8.
1974: Allen D Roses; S H Appel
Letter: Muscular dystrophies.
Lancet 1974;2(7893):1400.
1974: D Allan Butterfield; Allen D Roses; M L Cooper; S H Appel; D B Chesnut
A comparative electron spin resonance study of the erythrocyte membrane in myotonic muscular dystrophy.
Biochemistry 1974;13(25):5078-82.
1974: Allen D Roses; S H Appel
Muscle membrane protein kinase in myotonic muscular dystrophy.
Nature 1974;250(463):245-7.
1974: D Allan Butterfield; D B Chesnut; Allen D Roses; S H Appel
Electron spin resonance studies of erythrocytes from patients with myotonic muscular dystrophy.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(3):909-13.
1973: C G Andrew; Allen D Roses; R R Almon; S H Appel
Phosphorylation of muscle membranes: identification of a membrane-bound protein kinase.
Science (New York, N.Y.) 1973;182(4115):927-9.
1973: Allen D Roses; S H Appel
Protein kinase activity in erythrocyte ghosts of patients with myotonic muscular dystrophy.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(6):1855-9.
1973: Allen D Roses; S H Appel
Erythrocyte protein phosphorylation.
The Journal of biological chemistry 1973;248(4):1408-11.