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Allen Roses

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Roses A D
Stimulation of cholecystokinin-A receptors with Gl181771X: a failed clinical trial that did not test the pharmacogenetic hypothesis for reduction of food intake.
Roses Allen D
Pharmacogenetics in drug discovery and development: a translational perspective.
Akuffo Emma L; Davis John B; Fox Steven M; Gloger Israel S; Hosford David; Kinsey Emma E; Jones Neil A; Nock Christina M; Roses Allen D; Saunders Ann M; Skehel J Mark; Smith Marjorie A; Cutler Paul
The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone.

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All Publications

2009: Roses A D
Stimulation of cholecystokinin-A receptors with Gl181771X: a failed clinical trial that did not test the pharmacogenetic hypothesis for reduction of food intake.
Clinical pharmacology and therapeutics 2009;85(4):362-5.
2008: Roses Allen D
Pharmacogenetics in drug discovery and development: a translational perspective.
Nature reviews. Drug discovery 2008;7(10):807-17.
2008: Akuffo Emma L; Davis John B; Fox Steven M; Gloger Israel S; Hosford David; Kinsey Emma E; Jones Neil A; Nock Christina M; Roses Allen D; Saunders Ann M; Skehel J Mark; Smith Marjorie A; Cutler Paul
The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2008;13(6):618-36.
2008: Nelson Matthew R; Bryc Katarzyna; King Karen S; Indap Amit; Boyko Adam R; Novembre John; Briley Linda P; Maruyama Yuka; Waterworth Dawn M; Waeber Gérard; Vollenweider Peter; Oksenberg Jorge R; Hauser Stephen L; Stirnadel Heide A; Kooner Jaspal S; Chambers John C; Jones Brendan; Mooser Vincent; Bustamante Carlos D; Roses Allen D; Burns Daniel K; Ehm Margaret G; Lai Eric H
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research.
American journal of human genetics 2008;83(3):347-58.
2008: Netzer Christian; Freudenberg Jan; Heinze Axel; Heinze-Kuhn Katja; Goebel Ingrid; McCarthy Linda C; Roses Allen D; Göbel Hartmut; Todt Unda; Kubisch Christian
Replication study of the insulin receptor gene in migraine with aura.
Genomics 2008;91(6):503-7.
2008: Roses Allen D
Commentary on "a roadmap for the prevention of dementia: the inaugural Leon Thal Symposium." An impending prevention clinical trial for Alzheimer's disease: roadmaps and realities.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2008;4(3):164-6.
2008: Cogswell John P; Ward James; Taylor Ian A; Waters Michelle; Shi Yunling; Cannon Brian; Kelnar Kevin; Kemppainen Jon; Brown David; Chen Caifu; Prinjha Rab K; Richardson Jill C; Saunders Ann M; Roses Allen D; Richards Cynthia A
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways.
Journal of Alzheimer's disease : JAD 2008;14(1):27-41.
2008: Brodbeck Jens; Balestra Maureen E; Saunders Ann M; Roses Allen D; Mahley Robert W; Huang Yadong
Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(4):1343-6.
2008: Li Hao; Wetten Sally; Li Li; St Jean Pamela L; Upmanyu Ruchi; Surh Linda; Hosford David; Barnes Michael R; Briley James David; Borrie Michael; Coletta Natalie; Delisle Richard; Dhalla Daniella; Ehm Margaret G; Feldman Howard H; Fornazzari Luis; Gauthier Serge; Goodgame Neil; Guzman Danilo; Hammond Sandra; Hollingworth Paul; Hsiung Ging-Yuek; Johnson Joan; Kelly Devon D; Keren Ron; Kertesz Andrew; King Karen S; Lovestone Simon; Loy-English Inge; Matthews Paul M; Owen Michael J; Plumpton Mary; Pryse-Phillips William; Prinjha Rab K; Richardson Jill C; Saunders Ann; Slater Andrew J; St George-Hyslop Peter H; Stinnett Sandra W; Swartz Jina E; Taylor Rachel L; Wherrett John; Williams Julie; Yarnall David P; Gibson Rachel A; Irizarry Michael C; Middleton Lefkos T; Roses Allen D
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
Archives of neurology 2008;65(1):45-53.
2008: Zhu G; Carlsen K; Carlsen K-H; Lenney W; Silverman M; Whyte M K; Hosking L; Helms P; Roses A D; Hay D W; Barnes M R; Anderson W H; Pillai S G
Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations.
Genes and immunity 2008;9(1):23-9.
2007: Roses Allen D; St Jean Pamela L; Ehm Margaret G
Use of whole-genome association scans in disease gene identification, drug discovery and development.
IDrugs : the investigational drugs journal 2007;10(11):797-804.
2007: Roses A
"Personalized medicine: elusive dream or imminent reality?": A commentary.
Clinical pharmacology and therapeutics 2007;81(6):801-5.
2007: Warren L L; Hughes A R; Lai E H; Zaykin D V; Haneline S A; Bansal A T; Wooster A W; Spreen W R; Hernandez J E; Scott T R; Roses A D; Mosteller M;
Use of pairwise marker combination and recursive partitioning in a pharmacogenetic genome-wide scan.
The pharmacogenomics journal 2007;7(3):180-9.
2007: Roses A D; Saunders A M; Huang Y; Strum J; Weisgraber K H; Mahley R W
Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease).
The pharmacogenomics journal 2007;7(1):10-28.
2006: Risner M E; Saunders A M; Altman J F B; Ormandy G C; Craft S; Foley I M; Zvartau-Hind M E; Hosford D A; Roses A D;
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease.
The pharmacogenomics journal 2006;6(4):246-54.
2006: Roses Allen D; Saunders Ann M
Perspective on a pathogenesis and treatment of Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2006;2(2):59-70.
2006: Stankovich Jim; Cox Charles J; Tan Rachel B; Montgomery Douglas S; Huxtable Stewart J; Rubio Justin P; Ehm Margaret G; Johnson Laura; Butzkueven Helmut; Kilpatrick Trevor J; Speed Terence P; Roses Allen D; Bahlo Melanie; Foote Simon J
On the utility of data from the International HapMap Project for Australian association studies.
Human genetics 2006;119(1-2):220-2.
2006: Roses Allen D
On the discovery of the genetic association of Apolipoprotein E genotypes and common late-onset Alzheimer disease.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):361-6.
2005: Spraggs Colin F; Pillai Sreekumar G; Dow David; Douglas Christal; McCarthy Linda; Manasco Penelope K; Stubbins Michael; Roses Allen D
Pharmacogenetics and obesity: common gene variants influence weight loss response of the norepinephrine/dopamine transporter inhibitor GW320659 in obese subjects.
Pharmacogenetics and genomics 2005;15(12):883-9.
2005: Roses Allen D
Applying technologies towards safe and effective medicines.
BioTechniques 2005;39(4):563-4.
2005: Roses Allen D; Burns Daniel K; Chissoe Stephanie; Middleton Lefkos; St Jean Pamela
Disease-specific target selection: a critical first step down the right road.
Drug discovery today 2005;10(3):177-89.
2005: Ahmadi Kourosh R; Weale Mike E; Xue Zhengyu Y; Soranzo Nicole; Yarnall David P; Briley James D; Maruyama Yuka; Kobayashi Mikiro; Wood Nicholas W; Spurr Nigel K; Burns Daniel K; Roses Allen D; Saunders Ann M; Goldstein David B
A single-nucleotide polymorphism tagging set for human drug metabolism and transport.
Nature genetics 2005;37(1):84-9.
2005: Liu Chang; Ghosh Sujoy; Searls David B; Saunders Ann M; Cossman Jeffrey; Roses Allen D
Clusters of adjacent and similarly expressed genes across normal human tissues complicate comparative transcriptomic discovery.
Omics : a journal of integrative biology 2005;9(4):351-63.
2004: Nicodemus Kristin K; Stenger Judith E; Schmechel Donald E; Welsh-Bohmer Kathleen A; Saunders Ann M; Roses Allen D; Gilbert John R; Vance Jeffery M; Haines Jonathan L; Pericak-Vance Margaret A; Martin Eden R
Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease.
Neurogenetics 2004;5(4):201-8.
2004: Roses Allen D
Pharmacogenetics and drug development: the path to safer and more effective drugs.
Nature reviews. Genetics 2004;5(9):645-56.
2004: Austin Christopher P; Battey James F; Bradley Allan; Bucan Maja; Capecchi Mario; Collins Francis S; Dove William F; Duyk Geoffrey; Dymecki Susan; Eppig Janan T; Grieder Franziska B; Heintz Nathaniel; Hicks Geoff; Insel Thomas R; Joyner Alexandra; Koller Beverly H; Lloyd K C Kent; Magnuson Terry; Moore Mark W; Nagy Andras; Pollock Jonathan D; Roses Allen D; Sands Arthur T; Seed Brian; Skarnes William C; Snoddy Jay; Soriano Philippe; Stewart David J; Stewart Francis; Stillman Bruce; Varmus Harold; Varticovski Lyuba; Verma Inder M; Vogt Thomas F; von Melchner Harald; Witkowski Jan; Woychik Richard P; Wurst Wolfgang; Yancopoulos George D; Young Stephen G; Zambrowicz Brian
The knockout mouse project.
Nature genetics 2004;36(9):921-4.
2004: Hauser Elizabeth R; Crossman David C; Granger Christopher B; Haines Jonathan L; Jones Christopher J H; Mooser Vincent; McAdam Brendan; Winkelmann Bernhard R; Wiseman Alan H; Muhlestein J Brent; Bartel Alan G; Dennis Charles A; Dowdy Elaine; Estabrooks Susan; Eggleston Karen; Francis Sheila; Roche Kath; Clevenger Paula W; Huang Liling; Pedersen Bonnie; Shah Svati; Schmidt Silke; Haynes Carol; West Sandra; Asper Donny; Booze Michael; Sharma Sanjay; Sundseth Scott; Middleton Lefkos; Roses Allen D; Hauser Michael A; Vance Jeffery M; Pericak-Vance Margaret A; Kraus William E
A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study.
American journal of human genetics 2004;75(3):436-47.
2004: van der Walt Joelle M; Dementieva Yulia A; Martin Eden R; Scott William K; Nicodemus Kristin K; Kroner Charles C; Welsh-Bohmer Kathleen A; Saunders Ann M; Roses Allen D; Small Gary W; Schmechel Donald E; Murali Doraiswamy P; Gilbert John R; Haines Jonathan L; Vance Jeffery M; Pericak-Vance Margaret A
Analysis of European mitochondrial haplogroups with Alzheimer disease risk.
Neuroscience letters 2004;365(1):28-32.
2004: North B V; Curtis D; Martin E R; Lai E H; Roses A D; Sham P C
Further investigation of linkage disequilibrium SNPs and their ability to identify associated susceptibility loci.
Annals of human genetics 2004;68(Pt 3):240-8.
2004: Hosford David A; Lai Eric H; Riley John H; Xu Chun-Fang; Danoff Theodore M; Roses Allen D
Pharmacogenetics to predict drug-related adverse events.
Toxicologic pathology 2004;32 Suppl 1():9-12.
2004: Hughes Arlene R; Mosteller Michael; Bansal Aruna T; Davies Kirstie; Haneline Stephen A; Lai Eric H; Nangle Keith; Scott Trevor; Spreen William R; Warren Liling L; Roses Allen D;
Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations.
Pharmacogenomics 2004;5(2):203-11.
2004: Xu C-F; Lewis K F; Yeo A J; McCarthy L C; Maguire M F; Anwar Z; Danoff T M; Roses A D; Purvis I J
Identification of a pharmacogenetic effect by linkage disequilibrium mapping.
The pharmacogenomics journal 2004;4(6):374-8.
2004: Danoff T M; Campbell D A; McCarthy L C; Lewis K F; Repasch M H; Saunders A M; Spurr N K; Purvis I J; Roses A D; Xu C-F
A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia.
The pharmacogenomics journal 2004;4(1):49-53.
2003: Li Yi-Ju; Oliveira Sofia A; Xu Puting; Martin Eden R; Stenger Judith E; Scherzer Clemens R; Hauser Michael A; Scott William K; Small Gary W; Nance Martha A; Watts Ray L; Hubble Jean P; Koller William C; Pahwa Rajesh; Stern Mathew B; Hiner Bradley C; Jankovic Joseph; Goetz Christopher G; Mastaglia Frank; Middleton Lefkos T; Roses Allen D; Saunders Ann M; Schmechel Donald E; Gullans Steven R; Haines Jonathan L; Gilbert John R; Vance Jeffery M; Pericak-Vance Margaret A; Hulette Christine; Welsh-Bohmer Kathleen A
Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease.
Human molecular genetics 2003;12(24):3259-67.
2003: Scott William K; Hauser Elizabeth R; Schmechel Donald E; Welsh-Bohmer Kathleen A; Small Gary W; Roses Allen D; Saunders Ann M; Gilbert John R; Vance Jeffery M; Haines Jonathan L; Pericak-Vance Margaret A
Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22.
American journal of human genetics 2003;73(5):1041-51.
2003: Schmith V D; Campbell D A; Sehgal S; Anderson W H; Burns D K; Middleton L T; Roses A D
Pharmacogenetics and disease genetics of complex diseases.
Cellular and molecular life sciences : CMLS 2003;60(8):1636-46.
2003: Levi Ofir; Jongen-Relo Ana L; Feldon Joram; Roses Allen D; Michaelson Daniel M
ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory.
Neurobiology of disease 2003;13(3):273-82.
2003: Oliveira Sofia A; Martin Eden R; Scott William K; Nicodemus Kristin K; Small Gary W; Schmechel Donald E; Doraiswamy P Murali; Roses Allen D; Saunders Ann M; Gilbert John R; Haines Jonathan L; Vance Jeffery M; Pericak-Vance Margaret A
The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease.
Neuroscience letters 2003;347(3):143-6.
2003: van der Walt J M; Martin E R; Scott W K; Zhang F; Nance M A; Watts R L; Hubble J P; Haines J L; Koller W C; Lyons K; Pahwa R; Stern M B; Colcher A; Hiner B C; Jankovic J; Ondo W G; Allen F H; Goetz C G; Small G W; Mastaglia F; Roses A D; Stajich J M; Booze M W; Fujiwara K; Gibson R A; Middleton L T; Scott B L; Pericak-Vance M A; Vance J M
Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease.
Neurology 2003;60(7):1189-91.
2003: Hauser Elizabeth R; Mooser Vincent; Crossman David C; Haines Jonathan L; Jones Christopher H; Winkelmann Bernhard R; Schmidt Silke; Scott William K; Roses Allen D; Pericak-Vance Margaret A; Granger Christopher B; Kraus William E;
Design of the Genetics of Early Onset Cardiovascular Disease (GENECARD) study.
American heart journal 2003;145(4):602-13.
2003: Norbert Paul W; Roses Allen D
Pharmacogenetics and pharmacogenomics: recent developments, their clinical relevance and some ethical, social, and legal implications.
Journal of molecular medicine (Berlin, Germany) 2003;81(3):135-40.
2003: Roses Allen D; Pangalos Menelas N
Drug development and Alzheimer disease.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2003;11(2):123-30.
2003: Ophir Gal; Meilin Sigal; Efrati Margalit; Chapman Joab; Karussis Dimitri; Roses Allen; Michaelson Daniel M
Human apoE3 but not apoE4 rescues impaired astrocyte activation in apoE null mice.
Neurobiology of disease 2003;12(1):56-64.
2003: Ezra Y; Oron L; Moskovich L; Roses A D; Beni S M; Shohami E; Michaelson D M
Apolipoprotein E4 decreases whereas apolipoprotein E3 increases the level of secreted amyloid precursor protein after closed head injury.
Neuroscience 2003;121(2):315-25.
2002: Lai Eric; Bowman Clive; Bansal Aruna; Hughes Arlene; Mosteller Michael; Roses Allen D
Medical applications of haplotype-based SNP maps: learning to walk before we run.
Nature genetics 2002;32(3):353.
2002: Roses Allen D
Genome-based pharmacogenetics and the pharmaceutical industry.
Nature reviews. Drug discovery 2002;1(7):541-9.
2002: Teter B; Xu P-T; Gilbert J R; Roses A D; Galasko D; Cole G M
Defective neuronal sprouting by human apolipoprotein E4 is a gain-of-negative function.
Journal of neuroscience research 2002;68(3):331-6.
2002: Li Yi-Ju; Scott William K; Hedges Dale J; Zhang Fengyu; Gaskell P Craig; Nance Martha A; Watts Ray L; Hubble Jean P; Koller William C; Pahwa Rajesh; Stern Matthew B; Hiner Bradley C; Jankovic Joseph; Allen Fred A; Goetz Christopher G; Mastaglia Frank; Stajich Jeffrey M; Gibson Rachel A; Middleton Lefkos T; Saunders Ann M; Scott Burton L; Small Gary W; Nicodemus Kristin K; Reed Allison D; Schmechel Donald E; Welsh-Bohmer Kathleen A; Conneally P Michael; Roses Allen D; Gilbert John R; Vance Jeffery M; Haines Jonathan L; Pericak-Vance Margaret A
Age at onset in two common neurodegenerative diseases is genetically controlled.
American journal of human genetics 2002;70(4):985-93.
2002: Hetherington Seth; Hughes Arlene R; Mosteller Michael; Shortino Denise; Baker Katherine L; Spreen William; Lai Eric; Davies Kirstie; Handley Abigail; Dow David J; Fling Mary E; Stocum Michael; Bowman Clive; Thurmond Linda M; Roses Allen D
Genetic variations in HLA-B region and hypersensitivity reactions to abacavir.
Lancet 2002;359(9312):1121-2.
2002: Hewett Duncan; Samuelsson Lena; Polding Joanne; Enlund Fredrik; Smart Devi; Cantone Kathryn; See Chee Gee; Chadha Sapna; Inerot Annica; Enerback Charlotta; Montgomery Doug; Christodolou Chris; Robinson Phil; Matthews Paul; Plumpton Mary; Wahlstrom Jan; Swanbeck Gunnar; Martinsson Tommy; Roses Allen; Riley John; Purvis Ian
Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map.
Genomics 2002;79(3):305-14.
2002: Roses Allen D
Pharmacogenetics place in modern medical science and practice.
Life sciences 2002;70(13):1471-80.
2002: Roses Allen D
SNPs--where's the beef?
The pharmacogenomics journal 2002;2(5):277-83.
2001: McCarthy L C; Hosford D A; Riley J H; Bird M I; White N J; Hewett D R; Peroutka S J; Griffiths L R; Boyd P R; Lea R A; Bhatti S M; Hosking L K; Hood C M; Jones K W; Handley A R; Rallan R; Lewis K F; Yeo A J; Williams P M; Priest R C; Khan P; Donnelly C; Lumsden S M; O'Sullivan J; See C G; Smart D H; Shaw-Hawkins S; Patel J; Langrish T C; Feniuk W; Knowles R G; Thomas M; Libri V; Montgomery D S; Manasco P K; Xu C F; Dykes C; Humphrey P P; Roses A D; Purvis I J
Single-nucleotide polymorphism alleles in the insulin receptor gene are associated with typical migraine.
Genomics 2001;78(3):135-49.
2001: Martin E R; Scott W K; Nance M A; Watts R L; Hubble J P; Koller W C; Lyons K; Pahwa R; Stern M B; Colcher A; Hiner B C; Jankovic J; Ondo W G; Allen F H; Goetz C G; Small G W; Masterman D; Mastaglia F; Laing N G; Stajich J M; Ribble R C; Booze M W; Rogala A; Hauser M A; Zhang F; Gibson R A; Middleton L T; Roses A D; Haines J L; Scott B L; Pericak-Vance M A; Vance J M
Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease.
JAMA : the journal of the American Medical Association 2001;286(18):2245-50.
2001: Scott W K; Nance M A; Watts R L; Hubble J P; Koller W C; Lyons K; Pahwa R; Stern M B; Colcher A; Hiner B C; Jankovic J; Ondo W G; Allen F H; Goetz C G; Small G W; Masterman D; Mastaglia F; Laing N G; Stajich J M; Slotterbeck B; Booze M W; Ribble R C; Rampersaud E; West S G; Gibson R A; Middleton L T; Roses A D; Haines J L; Scott B L; Vance J M; Pericak-Vance M A
Complete genomic screen in Parkinson disease: evidence for multiple genes.
JAMA : the journal of the American Medical Association 2001;286(18):2239-44.
2001: Roses A D
2025: the practice of neurology: back from the future.
Archives of neurology 2001;58(11):1766-7.
2001: Roses A D
Pharmacogenetics.
Human molecular genetics 2001;10(20):2261-7.
2001: White F; Nicoll J A; Roses A D; Horsburgh K
Impaired neuronal plasticity in transgenic mice expressing human apolipoprotein E4 compared to E3 in a model of entorhinal cortex lesion.
Neurobiology of disease 2001;8(4):611-25.
2000: Horsburgh K; McCulloch J; Nilsen M; Roses A D; Nicoll J A
Increased neuronal damage and apoE immunoreactivity in human apolipoprotein E, E4 isoform-specific, transgenic mice after global cerebral ischaemia.
The European journal of neuroscience 2000;12(12):4309-17.
2000: Pericak-Vance M A; Grubber J; Bailey L R; Hedges D; West S; Santoro L; Kemmerer B; Hall J L; Saunders A M; Roses A D; Small G W; Scott W K; Conneally P M; Vance J M; Haines J L
Identification of novel genes in late-onset Alzheimer's disease.
Experimental gerontology 2000;35(9-10):1343-52.
2000: Roses A D
Genetic susceptibility to cardiovascular diseases.
American heart journal 2000;140(4):S45-7.
2000: Wilkins M R; Roses A D; Clifford C P
Pharmacogenetics and the treatment of cardiovascular disease.
Heart (British Cardiac Society) 2000;84(4):353-4.
2000: Roses A D
Idiosyncratic reactions to drugs: can medicine response profiles provide a dynamic drug surveillance system?
Clinical chemistry and laboratory medicine : CCLM / FESCC 2000;38(9):815-8.
2000: Martin E R; Lai E H; Gilbert J R; Rogala A R; Afshari A J; Riley J; Finch K L; Stevens J F; Livak K J; Slotterbeck B D; Slifer S H; Warren L L; Conneally P M; Schmechel D E; Purvis I; Pericak-Vance M A; Roses A D; Vance J M
SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease.
American journal of human genetics 2000;67(2):383-94.
2000: Saunders A M; Trowers M K; Shimkets R A; Blakemore S; Crowther D J; Mansfield T A; Wallace D M; Strittmatter W J; Roses A D
The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection.
Biochimica et biophysica acta 2000;1502(1):85-94.
2000: Mounsey J P; John J E; Helmke S M; Bush E W; Gilbert J; Roses A D; Perryman M B; Jones L R; Moorman J R
Phospholemman is a substrate for myotonic dystrophy protein kinase.
The Journal of biological chemistry 2000;275(30):23362-7.
2000: Roses A D
Pharmacogenetics and the practice of medicine.
Nature 2000;405(6788):857-65.
2000: Roses A D
Causes or consequences of inflammation and pathological signs of Alzheimer disease.
Neurobiology of aging 2000;21(3):423-5.
2000: Small G W; Ercoli L M; Silverman D H; Huang S C; Komo S; Bookheimer S Y; Lavretsky H; Miller K; Siddarth P; Rasgon N L; Mazziotta J C; Saxena S; Wu H M; Mega M S; Cummings J L; Saunders A M; Pericak-Vance M A; Roses A D; Barrio J R; Phelps M E
Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):6037-42.
2000: Chen J; Iannone M A; Li M S; Taylor J D; Rivers P; Nelsen A J; Slentz-Kesler K A; Roses A; Weiner M P
A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension.
Genome research 2000;10(4):549-57.
2000: Riley K P; Snowdon D A; Saunders A M; Roses A D; Mortimer J A; Nanayakkara N
Cognitive function and apolipoprotein E in very old adults: findings from the Nun Study.
The journals of gerontology. Series B, Psychological sciences and social sciences 2000;55(2):S69-75.
2000: Horsburgh K; McCulloch J; Nilsen M; McCracken E; Large C; Roses A D; Nicoll J A
Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(3):458-62.
2000: Scott W K; Grubber J M; Conneally P M; Small G W; Hulette C M; Rosenberg C K; Saunders A M; Roses A D; Haines J L; Pericak-Vance M A
Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity.
American journal of human genetics 2000;66(3):922-32.
2000: Riley J H; Allan C J; Lai E; Roses A
The use of single nucleotide polymorphisms in the isolation of common disease genes.
Pharmacogenomics 2000;1(1):39-47.
2000: Martin E R; Gilbert J R; Lai E H; Riley J; Rogala A R; Slotterbeck B D; Sipe C A; Grubber J M; Warren L L; Conneally P M; Saunders A M; Schmechel D E; Purvis I; Pericak-Vance M A; Roses A D; Vance J M
Analysis of association at single nucleotide polymorphisms in the APOE region.
Genomics 2000;63(1):7-12.
2000: Sabo T; Lomnitski L; Nyska A; Beni S; Maronpot R R; Shohami E; Roses A D; Michaelson D M
Susceptibility of transgenic mice expressing human apolipoprotein E to closed head injury: the allele E3 is neuroprotective whereas E4 increases fatalities.
Neuroscience 2000;101(4):879-84.
2000: Roses A D
Pharmacogenetics and pharmacogenomics in the discovery and development of medicines.
Novartis Foundation symposium 2000;229():63-6; discussion 66-70.
2000: Chapman S; Sabo T; Roses A D; Michaelson D M
Reversal of presynaptic deficits of apolipoprotein E-deficient mice in human apolipoprotein E transgenic mice.
Neuroscience 2000;97(3):419-24.
1999: Boschert U; Merlo-Pich E; Higgins G; Roses A D; Catsicas S
Apolipoprotein E expression by neurons surviving excitotoxic stress.
Neurobiology of disease 1999;6(6):508-14.
1999: Teter B; Xu P T; Gilbert J R; Roses A D; Galasko D; Cole G M
Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture.
Journal of neurochemistry 1999;73(6):2613-6.
1999: Scott W K; Yamaoka L H; Stajich J M; Scott B L; Vance J M; Roses A D; Pericak-Vance M A; Watts R L; Nance M; Hubble J; Koller W; Stern M B; Colcher A; Allen F H; Hiner B C; Jankovic J; Ondo W; Laing N G; Mastaglia F; Goetz C; Pappert E; Small G W; Masterman D; Haines J L; Davies T L
The alpha-synuclein gene is not a major risk factor in familial Parkinson disease.
Neurogenetics 1999;2(3):191-2.
1999: Small G W; Scott W K; Komo S; Yamaoka L H; Farrer L A; Auerbach S H; Saunders A M; Roses A D; Haines J L; Pericak-Vance M A
No association between the HLA-A2 allele and Alzheimer disease.
Neurogenetics 1999;2(3):177-82.
1999: Hulette C M; Pericak-Vance M A; Roses A D; Schmechel D E; Yamaoka L H; Gaskell P C; Welsh-Bohmer K A; Crowther R A; Spillantini M G
Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684.
Journal of neuropathology and experimental neurology 1999;58(8):859-66.
1999: Grubber J M; Saunders A M; Crane-Gatherum A R; Scott W K; Martin E R; Haynes C S; Conneally P M; Small G W; Roses A D; Haines J L; Pericak-Vance M A
Analysis of association between Alzheimer disease and the K variant of butyrylcholinesterase (BCHE-K).
Neuroscience letters 1999;269(2):115-9.
1999: Small G W; Chen S T; Komo S; Ercoli L; Bookheimer S; Miller K; Lavretsky H; Saxena S; Kaplan A; Dorsey D; Scott W K; Saunders A M; Haines J L; Roses A D; Pericak-Vance M A
Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele.
The American journal of psychiatry 1999;156(7):1035-8.
1999: Rogaeva E A; Premkumar S; Grubber J; Serneels L; Scott W K; Kawarai T; Song Y; Hill D L; Abou-Donia S M; Martin E R; Vance J J; Yu G; Orlacchio A; Pei Y; Nishimura M; Supala A; Roberge B; Saunders A M; Roses A D; Schmechel D; Crane-Gatherum A; Sorbi S; Bruni A; Small G W; Conneally P M; Haines J L; Van Leuven F; St George-Hyslop P H; Farrer L A; Pericak-Vance M A
An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease.
Nature genetics 1999;22(1):19-22.
1999: Horsburgh K; Kelly S; McCulloch J; Higgins G A; Roses A D; Nicoll J A
Increased neuronal damage in apolipoprotein E-deficient mice following global ischaemia.
Neuroreport 1999;10(4):837-41.
1999: Xu P T; Schmechel D; Qiu H L; Herbstreith M; Rothrock-Christian T; Eyster M; Roses A D; Gilbert J R
Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice.
Neurobiology of disease 1999;6(1):63-75.
1999: Scott W K; Grubber J M; Abou-Donia S M; Church T D; Saunders A M; Roses A D; Pericak-Vance M A; Conneally P M; Small G W; Haines J L
Further evidence linking late-onset Alzheimer disease with chromosome 12.
JAMA : the journal of the American Medical Association 1999;281(6):513-4.
1998: Einstein G; Patel V; Bautista P; Kenna M; Melone L; Fader R; Karson K; Mann S; Saunders A M; Hulette C; Mash D; Roses A D; Schmechel D E
Intraneuronal ApoE in human visual cortical areas reflects the staging of Alzheimer disease pathology.
Journal of neuropathology and experimental neurology 1998;57(12):1190-201.
1998: Roses A D
Apolipoprotein E and Alzheimer's disease. The tip of the susceptibility iceberg.
Annals of the New York Academy of Sciences 1998;855():738-43.
1998: Farrer L A; Abraham C R; Haines J L; Rogaeva E A; Song Y; McGraw W T; Brindle N; Premkumar S; Scott W K; Yamaoka L H; Saunders A M; Roses A D; Auerbach S A; Sorbi S; Duara R; Pericak-Vance M A; St George-Hyslop P H
Association between bleomycin hydrolase and Alzheimer's disease in caucasians.
Annals of neurology 1998;44(5):808-11.
1998: Lai E; Riley J; Purvis I; Roses A
A 4-Mb high-density single nucleotide polymorphism-based map around human APOE.
Genomics 1998;54(1):31-8.
1998: Williams K R; Saunders A M; Roses A D; Armati P J
Uptake and internalization of exogenous apolipoprotein E3 by cultured human central nervous system neurons.
Neurobiology of disease 1998;5(4):271-9.
1998: Gilbert J R; Guy V; Kumar A; Wolpert C; Kandt R; Aylesworth A; Roses A D; Pericak-Vance M A
Mutation and polymorphism analysis in the tuberous sclerosis 2 (TSC2) gene.
Neurogenetics 1998;1(4):267-72.
1998: Bass M P; Yamaoka L H; Scott W K; Gaskell P C; Welsh-Bohmer K A; Roses A D; Saunders A M; Haines J L; Pericak-Vance M A
No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients.
Neuroscience letters 1998;250(2):79-82.
1998: Mihovilovic M; Mai Y; Austin C; Roses A D
Sera from myasthenia gravis patients recognize the PEVK domain of titin.
Annals of the New York Academy of Sciences 1998;841():534-7.
1998: Mihovilovic M; Denning S; Mai Y; Fisher C M; Whichard L P; Patel D D; Roses A D
Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5, and beta-4 subunits of neuronal nicotinic acetylcholine receptors. Preferential transcription of the alpha-3 and beta-4 genes by immature CD4+8+ thymocytes and evidence for response to nicotine in thymocytes.
Annals of the New York Academy of Sciences 1998;841():388-92.
1998: Tamaoka A; Fraser P E; Ishii K; Sahara N; Ozawa K; Ikeda M; Saunders A M; Komatsuzaki Y; Sherrington R; Levesque G; Yu G; Rogaeva E; Shoji S; Nee L E; Pollen D A; Hendriks L; Martin J J; Van Broeckhoven C; Roses A D; Farrer L A; St George-Hyslop P H; Mori H
Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease.
Brain research. Molecular brain research 1998;56(1-2):178-85.
1998: Laskowitz D T; Horsburgh K; Roses A D
Apolipoprotein E and the CNS response to injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(5):465-71.
1998: Xu P T; Gilbert J R; Qiu H L; Rothrock-Christian T; Settles D L; Roses A D; Schmechel D E
Regionally specific neuronal expression of human APOE gene in transgenic mice.
Neuroscience letters 1998;246(2):65-8.
1998: Scott B L; Welch K; deSerrano V; Moss N C; Roses A D; Strittmatter W J
Human apolipoprotein E accelerates microtubule polymerization in vitro.
Neuroscience letters 1998;245(2):105-8.
1998: Sheng H; Laskowitz D T; Bennett E; Schmechel D E; Bart R D; Saunders A M; Pearlstein R D; Roses A D; Warner D S
Apolipoprotein E isoform-specific differences in outcome from focal ischemia in transgenic mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(4):361-6.
1998: Scott W K; Yamaoka L H; Bass M P; Gaskell P C; Conneally P M; Small G W; Farrer L A; Auerbach S A; Saunders A M; Roses A D; Haines J L; Pericak-Vance M A
No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease.
Neurogenetics 1998;1(3):179-83.
1998: Roses A D
Genetic associations.
Lancet 1998;351(9106):916.
1998: Guyton J R; Miller S E; Martin M E; Khan W A; Roses A D; Strittmatter W J
Novel large apolipoprotein E-containing lipoproteins of density 1.006-1.060 g/ml in human cerebrospinal fluid.
Journal of neurochemistry 1998;70(3):1235-40.
1998: Roses A D
Alzheimer diseases: a model of gene mutations and susceptibility polymorphisms for complex psychiatric diseases.
American journal of medical genetics 1998;81(1):49-57.
1998: Mayeux R; Saunders A M; Shea S; Mirra S; Evans D; Roses A D; Hyman B T; Crain B; Tang M X; Phelps C H
Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. Alzheimer's Disease Centers Consortium on Apolipoprotein E and Alzheimer's Disease.
The New England journal of medicine 1998;338(8):506-11.
1998: Roses A D; Gilbert J; Xu P T; Sullivan P; Popko B; Burkhart D S; Christian-Rothrock T; Saunders A M; Maeda N; Schmechel D E
Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice.
Neurobiology of aging 1998;19(1 Suppl):S53-8.
1998: Pericak-Vance M A; Bass M L; Yamaoka L H; Gaskell P C; Scott W K; Terwedow H A; Menold M M; Conneally P M; Small G W; Saunders A M; Roses A D; Haines J L
Complete genomic screen in late-onset familial Alzheimer's disease.
Neurobiology of aging 1998;19(1 Suppl):S39-42.
1998: Robertson T A; Dutton N S; Martins R N; Roses A D; Kakulas B A; Papadimitriou J M
Age-related congophilic inclusions in the brains of apolipoprotein E-deficient mice.
Neuroscience 1998;82(1):171-80.
1998: Roses A D
Genetic testing and Alzheimer disease: the promise.
Alzheimer disease and associated disorders 1998;12 Suppl 3():S3-9.
1998: Thomas A M; Cohen G; Cook-Deegan R M; O'Sullivan J; Post S G; Roses A D; Schaffner K F; Green R M
Alzheimer testing at Silver Years.
Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees 1998;7(3):294-307.
1997: Okochi M; Ishii K; Usami M; Sahara N; Kametani F; Tanaka K; Fraser P E; Ikeda M; Saunders A M; Hendriks L; Shoji S I; Nee L E; Martin J J; Van Broeckhoven C; St George-Hyslop P H; Roses A D; Mori H
Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations.
FEBS letters 1997;418(1-2):162-6.
1997: Mihovilovic M; Denning S; Mai Y; Whichard L P; Patel D D; Roses A D
Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5 and beta-4 subunits of neuronal nicotinic acetylcholine receptors: preferential transcription of the alpha-3 and beta-4 genes by immature CD4 + 8 + thymocytes.
Journal of neuroimmunology 1997;79(2):176-84.
1997: Stajich J M; Gilchrist J M; Lennon F; Lee A; Yamaoka L; Rosi B; Gaskell P C; Pritchard M; Donald L; Roses A D; Vance J M; Pericak-Vance M A
Confirmation of linkage of oculopharyngeal muscular dystrophy to chromosome 14q11.2-q13 in American families suggests the existence of a second causal mutation.
Neuromuscular disorders : NMD 1997;7 Suppl 1():S75-81.
1997: Roses A D
Genetic testing for Alzheimer disease. Practical and ethical issues.
Archives of neurology 1997;54(10):1226-9.
1997: Pericak-Vance M A; Bass M P; Yamaoka L H; Gaskell P C; Scott W K; Terwedow H A; Menold M M; Conneally P M; Small G W; Vance J M; Saunders A M; Roses A D; Haines J L
Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.
JAMA : the journal of the American Medical Association 1997;278(15):1237-41.
1997: Speer M C; Pericak-Vance M A; Stajich J M; Sarrica J; Jordan M; Roses A D; Vance J M; Gilbert J R
Further exclusion of FSHD1B from the telomeric region of 10q.
Neurogenetics 1997;1(2):151-2.
1997: Roses A D; Saunders A M
ApoE, Alzheimer's disease, and recovery from brain stress.
Annals of the New York Academy of Sciences 1997;826():200-12.
1997: Tardiff B E; Newman M F; Saunders A M; Strittmatter W J; Blumenthal J A; White W D; Croughwell N D; Davis R D; Roses A D; Reves J G
Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center.
The Annals of thoracic surgery 1997;64(3):715-20.
1997: Scott W K; Saunders A M; Gaskell P C; Locke P A; Growdon J H; Farrer L A; Auerbach S A; Roses A D; Haines J L; Pericak-Vance M A
Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease.
Annals of neurology 1997;42(3):376-8.
1997: Welsh-Bohmer K A; Gearing M; Saunders A M; Roses A D; Mirra S
Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease.
Annals of neurology 1997;42(3):319-25.
1997: Onodera O; Burke J R; Miller S E; Hester S; Tsuji S; Roses A D; Strittmatter W J
Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells.
Biochemical and biophysical research communications 1997;238(2):599-605.
1997: Mitsuda N; Roses A D; Vitek M P
Transcriptional regulation of the mouse presenilin-1 gene.
The Journal of biological chemistry 1997;272(38):23489-97.
1997: Scott W K; Staijich J M; Yamaoka L H; Speer M C; Vance J M; Roses A D; Pericak-Vance M A
Genetic complexity and Parkinson's disease. Deane Laboratory Parkinson Disease Research Group.
Science (New York, N.Y.) 1997;277(5324):387-8; author reply 389.
1997: Laskowitz D T; Sheng H; Bart R D; Joyner K A; Roses A D; Warner D S
Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(7):753-8.
1997: Roses A D
Alzheimer's disease: the genetics of risk.
Hospital practice (1995) 1997;32(7):51-5, 58-63, 67-9.
1997: Roses A D; Saunders A M
Clinical overdiagnosis of vascular dementia versus necropsy confirmed series.
Journal of neurology, neurosurgery, and psychiatry 1997;62(6):677-8.
1997: Hulette C M; Welsh-Bohmer K A; Crain B; Szymanski M H; Sinclaire N O; Roses A D
Rapid brain autopsy. The Joseph and Kathleen Bryan Alzheimer's Disease Research Center experience.
Archives of pathology & laboratory medicine 1997;121(6):615-8.
1997: Roses A D
A model for susceptibility polymorphisms for complex diseases: apolipoprotein E and Alzheimer disease.
Neurogenetics 1997;1(1):3-11.
1997: Alexander G E; Saunders A M; Szczepanik J; Strassburger T L; Pietrini P; Dani A; Furey M L; Mentis M J; Roses A D; Rapoport S I; Schapiro M B
Relation of age and apolipoprotein E to cognitive function in Down syndrome adults.
Neuroreport 1997;8(8):1835-40.
1997: Alberts M J; Davis J P; Graffagnino C; McClenny C; Delong D; Granger C; Herbstreith M H; Boteva K; Marchuk D A; Roses A D
Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage.
Annals of neurology 1997;41(5):683-6.
1997: Roses A D
Mutational and susceptibility genetics are different clinical paradigms.
International psychogeriatrics / IPA 1997;9(1):7-10.
1997: Small G W; Noble E P; Matsuyama S S; Jarvik L F; Komo S; Kaplan A; Ritchie T; Pritchard M L; Saunders A M; Conneally P M; Roses A D; Haines J L; Pericak-Vance M A
D2 dopamine receptor A1 allele in Alzheimer disease and aging.
Archives of neurology 1997;54(3):281-5.
1997: Roses A D; Saunders A M
Prediction for unimpaired subjects is different from diagnosis of demented patients.
Annals of neurology 1997;41(3):414-6.
1997: Post S G; Whitehouse P J; Binstock R H; Bird T D; Eckert S K; Farrer L A; Fleck L M; Gaines A D; Juengst E T; Karlinsky H; Miles S; Murray T H; Quaid K A; Relkin N R; Roses A D; St George-Hyslop P H; Sachs G A; Steinbock B; Truschke E F; Zinn A B
The clinical introduction of genetic testing for Alzheimer disease. An ethical perspective.
JAMA : the journal of the American Medical Association 1997;277(10):832-6.
1997: Lippa C F; Smith T W; Saunders A M; Hulette C; Pulaski-Salo D; Roses A D
Apolipoprotein E-epsilon 2 and Alzheimer's disease: genotype influences pathologic phenotype.
Neurology 1997;48(2):515-9.
1997: Robertson T A; Dutton N S; Martins R N; Roses A D; Kakulas B A; Papadimitriou J M
Beta-amyloid protein-containing inclusions in skeletal muscle of apolipoprotein-E-deficient mice.
The American journal of pathology 1997;150(2):417-27.
1997: Roses A D; Saunders A M
Apolipoprotein E genotyping as a diagnostic adjunct for Alzheimer's disease.
International psychogeriatrics / IPA 1997;9 Suppl 1():277-88; discussion 317-21.
1997: Roses A D
Apolipoprotein E, a gene with complex biological interactions in the aging brain.
Neurobiology of disease 1997;4(3-4):170-85.
1997: Williams K R; Pye V; Saunders A M; Roses A D; Armati P J
Apolipoprotein E uptake and low-density lipoprotein receptor-related protein expression by the NTera2/D1 cell line: a cell culture model of relevance for late-onset Alzheimer's disease.
Neurobiology of disease 1997;4(1):58-67.
1997: Scott W K; Yamaoka L H; Locke P A; Rosi B L; Gaskell P C; Saunders A M; Conneally P M; Small G W; Farrer L A; Growdon J H; Roses A D; Pericak-Vance M A; Haines J L
No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease.
Genetic epidemiology 1997;14(3):307-15.
1997: Kumar A; Kandt R S; Wolpert C; Roses A D; Pericak-Vance M A; Gilbert J R
A novel splice site mutation (156 + 1G-->A) in the TSC2 gene.
Human mutation 1997;9(1):64-5.
1996: Small G W; Komo S; La Rue A; Saxena S; Phelps M E; Mazziotta J C; Saunders A M; Haines J L; Pericak-Vance M A; Roses A D
Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging.
Annals of the New York Academy of Sciences 1996;802():70-8.
1996: Roses A D
Apolipoprotein E and Alzheimer's disease. A rapidly expanding field with medical and epidemiological consequences.
Annals of the New York Academy of Sciences 1996;802():50-7.
1996: Haines J L; Pritchard M L; Saunders A M; Schildkraut J M; Growdon J H; Gaskell P C; Farrer L A; Auerbach S A; Gusella J F; Locke P A; Rosi B L; Yamaoka L; Small G W; Conneally P M; Roses A D; Pericak-Vance M
No association between alpha 1-antichymotrypsin and familial Alzheimer's disease.
Annals of the New York Academy of Sciences 1996;802():35-41.
1996: Onodera O; Roses A D; Tsuji S; Vance J M; Strittmatter W J; Burke J R
Toxicity of expanded polyglutamine-domain proteins in Escherichia coli.
FEBS letters 1996;399(1-2):135-9.
1996: Roses A D; Saunders A M
Evaluation of suspected dementia.
The New England journal of medicine 1996;335(26):1996; author reply 1997-8.
1996: Roses A D; Bryan J; Bryan K
Apolipoprotein E genotype: utility in clinical practice in Alzheimer's disease.
Journal of the American Geriatrics Society 1996;44(12):1479-81.
1996: Yamaoka L H; Welsh-Bohmer K A; Hulette C M; Gaskell P C; Murray M; Rimmler J L; Helms B R; Guerra M; Roses A D; Schmechel D E; Pericak-Vance M A
Linkage of frontotemporal dementia to chromosome 17: clinical and neuropathological characterization of phenotype.
American journal of human genetics 1996;59(6):1306-12.
1996: Stajich J M; Gilchrist J M; Lennon F; Lee A; Yamaoka L; Helms B; Gaskell P C; Donald L; Roses A D; Vance J M; Pericak-Vance M A
Confirmation of linkage of oculopharyngeal muscular dystrophy to chromosome 14q11.2-q13.
Annals of neurology 1996;40(5):801-4.
1996: Roses A D
The Alzheimer diseases.
Current opinion in neurobiology 1996;6(5):644-50.
1996: Roses A D
Apolipoprotein E in neurology.
Current opinion in neurology 1996;9(4):265-70.
1996: Askanas V; Engel W K; Mirabella M; Weisgraber K H; Saunders A M; Roses A D; McFerrin J
Apolipoprotein E alleles in sporadic inclusion-body myositis and hereditary inclusion-body myopathy.
Annals of neurology 1996;40(2):264-5.
1996: Okuizumi K; Onodera O; Seki K; Tanaka H; Namba Y; Ikeda K; Saunders A M; Pericak-Vance M A; Roses A D; Tsuji S
Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease.
Annals of neurology 1996;40(2):251-4.
1996: Xia Y; Rohan de Silva H A; Rosi B L; Yamaoka L H; Rimmler J B; Pericak-Vance M A; Roses A D; Chen X; Masliah E; DeTeresa R; Iwai A; Sundsmo M; Thomas R G; Hofstetter C R; Gregory E; Hansen L A; Katzman R; Thal L J; Saitoh T
Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism.
Annals of neurology 1996;40(2):207-15.
1996: Haines J L; Ter-Minassian M; Bazyk A; Gusella J F; Kim D J; Terwedow H; Pericak-Vance M A; Rimmler J B; Haynes C S; Roses A D; Lee A; Shaner B; Menold M; Seboun E; Fitoussi R P; Gartioux C; Reyes C; Ribierre F; Gyapay G; Weissenbach J; Hauser S L; Goodkin D E; Lincoln R; Usuku K; Oksenberg J R
A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group.
Nature genetics 1996;13(4):469-71.
1996: Scott W K; Roses A D; Haines J L; Pericak-Vance M A
Presenilin-1 polymorphism and Alzheimer's disease.
Lancet 1996;347(9014):1560.
1996: Pritchard M L; Saunders A M; Gaskell P C; Small G W; Conneally P M; Rosi B; Yamaoka L H; Roses A D; Haines J L; Pericak-Vance M A
No association between very low density lipoprotein receptor (VLDL-R) and Alzheimer disease in American Caucasians.
Neuroscience letters 1996;209(2):105-8.
1996: Haines J L; Pritchard M L; Saunders A M; Schildkraut J M; Growdon J H; Gaskell P C; Farrer L A; Auerbach S A; Gusella J F; Locke P A; Rosi B L; Yamaoka L; Small G W; Conneally P M; Roses A D; Pericak-Vance M A
No genetic effect of alpha1-antichymotrypsin in Alzheimer disease.
Genomics 1996;33(1):53-6.
1996: Scott W K; Growdon J H; Roses A D; Haines J L; Pericak-Vance M A
Presenilin-1 polymorphism and Alzheimer's disease.
Lancet 1996;347(9009):1186-7.
1996: Burke J R; Enghild J J; Martin M E; Jou Y S; Myers R M; Roses A D; Vance J M; Strittmatter W J
Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.
Nature medicine 1996;2(3):347-50.
1996: Roses A D
From genes to mechanisms to therapies: lessons to be learned from neurological disorders.
Nature medicine 1996;2(3):267-9.
1996: Corder E H; Roses A D
No increased risk of the apolipoprotein E epsilon2 allele with early-onset Alzheimer's disease.
Annals of neurology 1996;39(3):414-6.
1996: Lippa C F; Saunders A M; Smith T W; Swearer J M; Drachman D A; Ghetti B; Nee L; Pulaski-Salo D; Dickson D; Robitaille Y; Bergeron C; Crain B; Benson M D; Farlow M; Hyman B T; George-Hyslop S P; Roses A D; Pollen D A
Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway.
Neurology 1996;46(2):406-12.
1996: Meckelein B; de Silva H A; Roses A D; Rao P N; Pettenati M J; Xu P T; Hodge R; Glucksman M J; Abraham C R
Human endopeptidase (THOP1) is localized on chromosome 19 within the linkage region for the late-onset alzheimer disease AD2 locus.
Genomics 1996;31(2):246-9.
1996: Roses A D; Einstein G; Gilbert J; Goedert M; Han S H; Huang D; Hulette C; Masliah E; Pericak-Vance M A; Saunders A M; Schmechel D E; Strittmatter W J; Weisgraber K H; Xi P T
Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism.
Annals of the New York Academy of Sciences 1996;777():146-57.
1996: Strittmatter W J; Burke J R; DeSerrano V S; Huang D Y; Matthew W; Saunders A M; Scott B L; Vance J M; Weisgraber K H; Roses A D
Protein: protein interactions in Alzheimer's disease and the CAG triplet repeat diseases.
Cold Spring Harbor symposia on quantitative biology 1996;61():597-605.
1996: Xu P T; Schmechel D; Rothrock-Christian T; Burkhart D S; Qiu H L; Popko B; Sullivan P; Maeda N; Saunders A M; Roses A D; Gilbert J R
Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.
Neurobiology of disease 1996;3(3):229-45.
1996: Strittmatter W J; Roses A D
Apolipoprotein E and Alzheimer's disease.
Annual review of neuroscience 1996;19():53-77.
1996: Roses A D
Apolipoprotein E alleles as risk factors in Alzheimer's disease.
Annual review of medicine 1996;47():387-400.
1995: Kumar A; Kandt R S; Wolpert C; Roses A D; Pericak-Vance M A; Gilbert J R
Mutation analysis of the TSC2 gene in an African-American family.
Human molecular genetics 1995;4(12):2295-8.
1995: Masliah E; Mallory M; Ge N; Alford M; Veinbergs I; Roses A D
Neurodegeneration in the central nervous system of apoE-deficient mice.
Experimental neurology 1995;136(2):107-22.
1995: Graffagnino C; Herbstreith M H; Schmechel D E; Levy E; Roses A D; Alberts M J
Cystatin C mutation in an elderly man with sporadic amyloid angiopathy and intracerebral hemorrhage.
Stroke; a journal of cerebral circulation 1995;26(11):2190-3.
1995: Ben Othmane K; Speer M C; Stauffer J; Blel S; Middleton L; Ben Hamida C; Etribi A; Loeb D; Hentati F; Roses A D
Evidence for linkage disequilibrium in chromosome 13-linked Duchenne-like muscular dystrophy (LGMD2C)
American journal of human genetics 1995;57(3):732-4.
1995: Kumar A; Wolpert C; Kandt R S; Segal J; Pufky J; Roses A D; Pericak-Vance M A; Gilbert J R
A de novo frame-shift mutation in the tuberin gene.
Human molecular genetics 1995;4(8):1471-2.
1995: Breitner J C; Welsh K A; Helms M J; Gaskell P C; Gau B A; Roses A D; Pericak-Vance M A; Saunders A M
Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs.
Neurobiology of aging 1995;16(4):523-30.
1995: Othmane K B; Loeb D; Hayworth-Hodgte R; Hentati F; Rao N; Roses A D; Ben Hamida M; Pericak-Vance M A; Vance J M
Physical and genetic mapping of the CMT4A locus and exclusion of PMP-2 as the defect in CMT4A.
Genomics 1995;28(2):286-90.
1995: Corder E H; Saunders A M; Pericak-Vance M A; Roses A D
There is a pathologic relationship between ApoE-epsilon 4 and Alzheimer's disease.
Archives of neurology 1995;52(7):650-1.
1995: Roses A D
Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease.
Annals of neurology 1995;38(1):6-14.
1995: Roses A D; Saunders A
Head injury, amyloid beta and Alzheimer's disease.
Nature medicine 1995;1(7):603-4.
1995: Huang D Y; Weisgraber K H; Goedert M; Saunders A M; Roses A D; Strittmatter W J
ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation.
Neuroscience letters 1995;192(3):209-12.
1995: Strittmatter W J; Roses A D
Apolipoprotein E and Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):4725-7.
1995: Mounsey J P; Xu P; John J E; Horne L T; Gilbert J; Roses A D; Moorman J R
Modulation of skeletal muscle sodium channels by human myotonin protein kinase.
The Journal of clinical investigation 1995;95(5):2379-84.
1995: Alberts M J; Quinones A; Graffagnino C; Friedman A; Roses A D
Risk of intracranial aneurysms in families with subarachnoid hemorrhage.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1995;22(2):121-5.
1995: Roses A D
On the metabolism of apolipoprotein E and the Alzheimer diseases.
Experimental neurology 1995;132(2):149-56.
1995: Roses A D; Saunders A M; Corder E H; Pericak-Vance M A; Han S H; Einstein G; Hulette C; Schmechel D E; Holsti M; Huang D
Influence of the susceptibility genes apolipoprotein E-epsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease.
Arzneimittel-Forschung 1995;45(3A):413-7.
1995: Chen X; de Silva H A; Pettenati M J; Rao P N; St George-Hyslop P; Roses A D; Xia Y; Horsburgh K; Uéda K; Saitoh T
The human NACP/alpha-synuclein gene: chromosome assignment to 4q21.3-q22 and TaqI RFLP analysis.
Genomics 1995;26(2):425-7.
1995: Roses A D; Saunders A M; Alberts M A; Strittmatter W J; Schmechel D; Gorder E; Pericak-Vance M A
Apolipoprotein E E4 allele and risk of dementia.
JAMA : the journal of the American Medical Association 1995;273(5):374-5; author reply 375-6.
1995: Corder E H; Saunders A M; Strittmatter W J; Schmechel D E; Gaskell P C; Roses A D; Pericak-Vance M A; Small G W; Haines J L
The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease.
JAMA : the journal of the American Medical Association 1995;273(5):373-4.
1995: Lippa C F; Smith T W; Saunders A M; Crook R; Pulaski-Salo D; Davies P; Hardy J; Roses A D; Dickson D
Apolipoprotein E genotype and Lewy body disease.
Neurology 1995;45(1):97-103.
1994: Roses A D; Saunders A M
APOE is a major susceptibility gene for Alzheimer's disease.
Current opinion in biotechnology 1994;5(6):663-7.
1994: Strittmatter W J; Saunders A M; Goedert M; Weisgraber K H; Dong L M; Jakes R; Huang D Y; Pericak-Vance M; Schmechel D; Roses A D
Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):11183-6.
1994: Goedert M; Strittmatter W J; Roses A D
Alzheimer's disease. Risky apolipoprotein in brain.
Nature 1994;372(6501):45-6.
1994: Huang D Y; Goedert M; Jakes R; Weisgraber K H; Garner C C; Saunders A M; Pericak-Vance M A; Schmechel D E; Roses A D; Strittmatter W J
Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease.
Neuroscience letters 1994;182(1):55-8.
1994: Graffagnino C; Herbstreith M H; Roses A D; Alberts M J
A molecular genetic study of intracerebral hemorrhage.
Archives of neurology 1994;51(10):981-4.
1994: Jensen T G; Roses A D; Jørgensen A L
Apolipoprotein E uptake and degradation via chloroquine-sensitive pathway in cultivated monkey cells overexpressing low density lipoprotein receptor.
Neuroscience letters 1994;180(2):193-6.
1994: Han S H; Einstein G; Weisgraber K H; Strittmatter W J; Saunders A M; Pericak-Vance M; Roses A D; Schmechel D E
Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study.
Journal of neuropathology and experimental neurology 1994;53(5):535-44.
1994: Roses A D
Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease.
Journal of neuropathology and experimental neurology 1994;53(5):429-37.
1994: Yamaoka L H; Westbrook C A; Speer M C; Gilchrist J M; Jabs E W; Schweins E G; Stajich J M; Gaskell P C; Roses A D; Pericak-Vance M A
Development of a microsatellite genetic map spanning 5q31-q33 and subsequent placement of the LGMD1A locus between D5S178 and IL9.
Neuromuscular disorders : NMD 1994;4(5-6):471-5.
1994: Näslund J; Schierhorn A; Hellman U; Lannfelt L; Roses A D; Tjernberg L O; Silberring J; Gandy S E; Winblad B; Greengard P
Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(18):8378-82.
1994: Sanan D A; Weisgraber K H; Russell S J; Mahley R W; Huang D; Saunders A; Schmechel D; Wisniewski T; Frangione B; Roses A D
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.
The Journal of clinical investigation 1994;94(2):860-9.
1994: Burke J R; Wingfield M S; Lewis K E; Roses A D; Lee J E; Hulette C; Pericak-Vance M A; Vance J M
The Haw River syndrome: dentatorubropallidoluysian atrophy (DRPLA) in an African-American family.
Nature genetics 1994;7(4):521-4.
1994: Han S H; Hulette C; Saunders A M; Einstein G; Pericak-Vance M; Strittmatter W J; Roses A D; Schmechel D E
Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls.
Experimental neurology 1994;128(1):13-26.
1994: Roses A D; Strittmatter W J; Pericak-Vance M A; Corder E H; Saunders A M; Schmechel D E
Clinical application of apolipoprotein E genotyping to Alzheimer's disease.
Lancet 1994;343(8912):1564-5.
1994: Peacock M L; Murman D L; Sima A A; Warren J T; Roses A D; Fink J K
Novel amyloid precursor protein gene mutation (codon 665Asp) in a patient with late-onset Alzheimer's disease.
Annals of neurology 1994;35(4):432-8.
1994: Weisgraber K H; Roses A D; Strittmatter W J
The role of apolipoprotein E in the nervous system.
Current opinion in lipidology 1994;5(2):110-6.
1994: Roses A D
Hereditary components in the neurodegerative diseases: Alzheimer's disease and myotonic dystrophy.
Neurobiology of aging 1994;15(2):243-5.
1994: Roses A D; Pericak-Vance M A; Saunders A M; Schmechel D; Goldgaber D; Strittmatter W
Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy?
Epilepsia 1994;35 Suppl 1():S20-8.
1994: Fink J K; Peacock M L; Warren J T; Roses A D; Prusiner S B
Detecting prion protein gene mutations by denaturing gradient gel electrophoresis.
Human mutation 1994;4(1):42-50.
1994: Roses A D
Apolipoprotein E is a relevant susceptibility gene that affects the rate of expression of Alzheimer's disease.
Neurobiology of aging 1994;15 Suppl 2():S165-7.
1993: Liepnieks J J; Ghetti B; Farlow M; Roses A D; Benson M D
Characterization of amyloid fibril beta-peptide in familial Alzheimer's disease with APP717 mutations.
Biochemical and biophysical research communications 1993;197(2):386-92.
1993: Mihovilovic M; Roses A D
Expression of alpha-3, alpha-5, and beta-4 neuronal acetylcholine receptor subunit transcripts in normal and myasthenia gravis thymus. Identification of thymocytes expressing the alpha-3 transcripts.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(11):6517-24.
1993: Mihovilovic M; Mai Y; Herbstreith M; Rubboli F; Tarroni P; Clementi F; Roses A D
Splicing of an anti-sense Alu sequence generates a coding sequence variant for the alpha-3 subunit of a neuronal acetylcholine receptor.
Biochemical and biophysical research communications 1993;197(1):137-44.
1993: Huang D; Martin M; Hu D; Roses A D; Goldgaber D; Strittmatter W J
Binding of IgG to amyloid beta A4 peptide via the heavy-chain hinge region with preservation of antigen binding.
Journal of neuroimmunology 1993;48(2):199-203.
1993: Schmechel D E; Saunders A M; Strittmatter W J; Crain B J; Hulette C M; Joo S H; Pericak-Vance M A; Goldgaber D; Roses A D
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9649-53.
1993: Ben Othmane K; Hentati F; Lennon F; Ben Hamida C; Blel S; Roses A D; Pericak-Vance M A; Ben Hamida M; Vance J M
Linkage of a locus (CMT4A) for autosomal recessive Charcot-Marie-Tooth disease to chromosome 8q.
Human molecular genetics 1993;2(10):1625-8.
1993: Strittmatter W J; Weisgraber K H; Huang D Y; Dong L M; Salvesen G S; Pericak-Vance M; Schmechel D; Saunders A M; Goldgaber D; Roses A D
Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):8098-102.
1993: Goldgaber D; Schwarzman A I; Bhasin R; Gregori L; Schmechel D; Saunders A M; Roses A D; Strittmatter W J
Sequestration of amyloid beta-peptide.
Annals of the New York Academy of Sciences 1993;695():139-43.
1993: Saunders A M; Roses A D
Apolipoprotein E4 allele frequency, ischemic cerebrovascular disease, and Alzheimer's disease.
Stroke; a journal of cerebral circulation 1993;24(9):1416-7.
1993: Ben Othmane K; Middleton L T; Loprest L J; Wilkinson K M; Lennon F; Rozear M P; Stajich J M; Gaskell P C; Roses A D; Pericak-Vance M A
Localization of a gene (CMT2A) for autosomal dominant Charcot-Marie-Tooth disease type 2 to chromosome 1p and evidence of genetic heterogeneity.
Genomics 1993;17(2):370-5.
1993: Strittmatter W J; Huang D Y; Bhasin R; Roses A D; Goldgaber D
Avid binding of beta A amyloid peptide to its own precursor.
Experimental neurology 1993;122(2):327-34.
1993: Phillips K L; Gartrell D M; Roses A D; Lee J E
A triplet repeat polymorphism in a gene expressed in human hypothalamus.
Human molecular genetics 1993;2(8):1332.
1993: Corder E H; Saunders A M; Strittmatter W J; Schmechel D E; Gaskell P C; Small G W; Roses A D; Haines J L; Pericak-Vance M A
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
Science (New York, N.Y.) 1993;261(5123):921-3.
1993: Mihovilovic M; Hulette C; Mittelstaedt J; Austin C; Roses A D
Nicotinic neuronal acetylcholine receptor alpha-3 subunit transcription in normal and myasthenic thymus.
Annals of the New York Academy of Sciences 1993;681():83-96.
1993: Peacock M L; Warren J T; Roses A D; Fink J K
Novel polymorphism in the A4 region of the amyloid precursor protein gene in a patient without Alzheimer's disease.
Neurology 1993;43(6):1254-6.
1993: Zeldenrust S R; Murrell J; Farlow M; Ghetti B; Roses A D; Benson M D
RFLP analysis for APP 717 mutations associated with Alzheimer's disease.
Journal of medical genetics 1993;30(6):476-8.
1993: Strittmatter W J; Saunders A M; Schmechel D; Pericak-Vance M; Enghild J; Salvesen G S; Roses A D
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(5):1977-81.
1993: Roses A D
Molecular genetics of neurodegenerative diseases.
Current opinion in neurology and neurosurgery 1993;6(1):34-9.
1993: Pericak-Vance M A; St George-Hyslop P H; Gaskell P C; Growdon J; Crain B J; Hulette C; Gusella J F; Yamaoka L; Tanzi R E; Roses A D
Linkage analysis in familial Alzheimer disease: description of the Duke and Boston data sets.
Genetic epidemiology 1993;10(6):361-4.
1992: Ben Othmane K; Ben Hamida M; Pericak-Vance M A; Ben Hamida C; Blel S; Carter S C; Bowcock A M; Petruhkin K; Gilliam T C; Roses A D
Linkage of Tunisian autosomal recessive Duchenne-like muscular dystrophy to the pericentromeric region of chromosome 13q.
Nature genetics 1992;2(4):315-7.
1992: Alberts M J; Ioannou P; Deucher R; Gilbert J; Lee J; Middleton L; Roses A D
Isolation of a cytochrome oxidase gene overexpressed in Alzheimer's disease brain.
Molecular and cellular neurosciences 1992;3(5):461-70.
1992: Phillips K L; Garbutt J H; Roses A D; Lee J E
A chromosome 19 CA-dinucleotide repeat polymorphism.
Human molecular genetics 1992;1(7):551.
1992: Gilbert J R; Stajich J M; Speer M C; Vance J M; Stewart C S; Yamaoka L H; Samson F; Fardeau M; Potter T G; Roses A D
Linkage studies in facioscapulohumeral muscular dystrophy (FSHD).
American journal of human genetics 1992;51(2):424-7.
1992: Samson F; de Jong P J; Trask B J; Koza-Taylor P; Speer M C; Potter T; Roses A D; Gilbert J R
Assignment of the human slow skeletal troponin T gene to 19q13.4 using somatic cell hybrids and fluorescence in situ hybridization analysis.
Genomics 1992;13(4):1374-5.
1992: Pröschel M; Saunders A; Roses A D; Müller C R
Dinucleotide repeat polymorphism at the human gene for the brain-derived neurotrophic factor (BDNF).
Human molecular genetics 1992;1(5):353.
1992: Small K W; Weber J L; Roses A; Lennon F; Vance J M; Pericak-Vance M A
North Carolina macular dystrophy is assigned to chromosome 6.
Genomics 1992;13(3):681-5.
1992: Pritchard C; Zhu N; Zuo J; Bull L; Pericak-Vance M A; Vance J M; Roses A D; Milatovich A; Francke U; Cox D R
Recombination of 4p16 DNA markers in an unusual family with Huntington disease.
American journal of human genetics 1992;50(6):1218-30.
1992: Sharp N J; Kornegay J N; Van Camp S D; Herbstreith M H; Secore S L; Kettle S; Hung W Y; Constantinou C D; Dykstra M J; Roses A D
An error in dystrophin mRNA processing in golden retriever muscular dystrophy, an animal homologue of Duchenne muscular dystrophy.
Genomics 1992;13(1):115-21.
1992: Constantinou-Deltas C D; Gilbert J; Bartlett R J; Herbstreith M; Roses A D; Lee J E
The identification and characterization of KRAB-domain-containing zinc finger proteins.
Genomics 1992;12(3):581-9.
1992: Loprest L J; Pericak-Vance M A; Stajich J; Gaskell P C; Lucas A M; Lennon F; Yamaoka L H; Roses A D; Vance J M
Linkage studies in Charcot-Marie-Tooth disease type 2: evidence that CMT types 1 and 2 are distinct genetic entities.
Neurology 1992;42(3 Pt 1):597-601.
1992: Kazantsev A; Yamaoka L H; Roses A D
A dinucleotide repeat polymorphism in the human Na+,K+ ATPase, alpha subunit (ATP1A3) gene.
Nucleic acids research 1992;20(5):1164.
1992: Roses A; Alberts M; Strittmatter W
Alzheimer's disease - reassessing the data.
Current biology : CB 1992;2(1):7-9.
1991: Samson F; Gilbert J R; Koza-Taylor P; Speer M C; Lee J; Roses A D
A PstI polymorphism detected by a genomic clone at the human slow troponin T (TNNT1) gene locus.
Nucleic acids research 1991;19(21):6058.
1991: Lucas A M; Vance J M; Stajich J M; Roses A D
A PvuII polymorphism detected by pEW404 (D17S64) on chromosome 17.
Nucleic acids research 1991;19(20):5802.
1991: Schellenberg G D; Anderson L; O'dahl S; Wisjman E M; Sadovnick A D; Ball M J; Larson E B; Kukull W A; Martin G M; Roses A D
APP717, APP693, and PRIP gene mutations are rare in Alzheimer disease.
American journal of human genetics 1991;49(3):511-7.
1991: Alberts M J; Pericak-Vance M A; Royal V; Bebout J; Gaskell P; Thomas J; Hung W Y; Clark C; Earl N; Roses A D
Genetic linkage analysis of nerve growth factor (beta) in familial Alzheimer's disease.
Annals of neurology 1991;30(2):216-9.
1991: Royal V; Alberts M J; Pericak-Vance M A; Finocchiaro G; Bebout J; Yamaoka L; Hung W Y; Gaskell P C; Roses A D
RsaI RFLP for electron transport flavoprotein-beta(ETFB).
Nucleic acids research 1991;19(14):4021.
1991: Roses A D; Conneally P M
Alzheimer's disease cell bank.
Science (New York, N.Y.) 1991;252(5002):14.
1991: Vance J M; Barker D; Yamaoka L H; Stajich J M; Loprest L; Hung W Y; Fischbeck K; Roses A D; Pericak-Vance M A
Localization of Charcot-Marie-Tooth disease type 1a (CMT1A) to chromosome 17p11.2.
Genomics 1991;9(4):623-8.
1991: Mihovilovic M; Roses A D
Expression of mRNAs in human thymus coding for the alpha 3 subunit of a neuronal acetylcholine receptor.
Experimental neurology 1991;111(2):175-80.
1991: Alberts M J; Kandt R S; Pericak-Vance M A; Bebout J; Speer M C; Siddique T S; Yamaoka L; Hung W Y; Gaskell P C; Roses A D
MspI RFLP for microtubule associated protein-2 (MAP2).
Nucleic acids research 1991;19(4):960.
1991: Speer M C; Goldgaber D; Goldfarb L G; Roses A D; Pericak-Vance M A
Support of linkage of Gerstmann-Sträussler-Scheinker syndrome to the prion protein gene on chromosome 20p12-pter.
Genomics 1991;9(2):366-8.
1991: Burke J R; Roses A D
Genetics of Alzheimer's disease.
International journal of neurology 1991;25-26():41-51.
1991: Kandt R S; Pericak-Vance M A; Hung W Y; Gardner R J; Crossen P E; Nellist M D; Speer M C; Roses A D
Linkage studies in tuberous sclerosis. Chromosome 9?, 11?, or maybe 14!
Annals of the New York Academy of Sciences 1991;615():284-97.
1990: Samson F; Lee J E; Hung W Y; Potter T G; Herbstreith M; Roses A D; Gilbert J R
Isolation and localization of a slow troponin (TnT) gene on chromosome 19 by subtraction hybridization of a cDNA muscle library using myotonic dystrophy muscle cDNA.
Journal of neuroscience research 1990;27(4):441-51.
1990: Speer M C; Pericak-Vance M A; Yamaoka L; Hung W Y; Ashley A; Stajich J M; Roses A D
Presymptomatic and prenatal diagnosis in myotonic dystrophy by genetic linkage studies.
Neurology 1990;40(4):671-6.
1990: Vance J M; Small K W; Jones M A; Stajich J M; Yamaoka L H; Roses A D; Hung W Y; Pericak-Vance M A
Confirmation of linkage in von Hippel-Lindau disease.
Genomics 1990;6(3):565-7.
1990: Roses A D; Pericak-Vance M A; Clark C M; Gilbert J R; Yamaoka L H; Haynes C S; Speer M C; Gaskell P C; Hung W Y; Trofatter J A
Linkage studies of late-onset familial Alzheimer's disease.
Advances in neurology 1990;51():185-96.
1990: Bartlett R J; Sharp N J; Hung W Y; Kornegay J N; Roses A D
Molecular markers for myoblast transplantation in GRMD.
Advances in experimental medicine and biology 1990;280():273-8.
1989: Lee J E; Garbutt J H; Pufky J; Ciccone C; Walker A; Bartlett R; Roses A D
A polymorphic DNA sequence (174-3.7) on chromosome 19 [D19S58]
Nucleic acids research 1989;17(23):10144.
1989: Roses A D
A conservative viewpoint on linkage in Alzheimer's disease.
Neurobiology of aging 1989;10(5):427-9; discussion 446-8.
1989: Siddique T; Roper H; Pericak-Vance M A; Shaw J; Warner K L; Hung W Y; Phillips K L; Lunt P; Cumming W J; Roses A D
Linkage analysis in the spinal muscular atrophy type of facioscapulohumeral disease.
Journal of medical genetics 1989;26(8):487-9.
1989: Laing N G; Siddique T; Bartlett R; Yamaoka L H; Hung W Y; Pericak-Vance M A; Roses A D
Duchenne muscular dystrophy: detection of deletion carriers by spectrophotometric densitometry.
Clinical genetics 1989;35(6):393-8.
1989: Vance J M; Nicholson G A; Yamaoka L H; Stajich J; Stewart C S; Speer M C; Hung W Y; Roses A D; Barker D; Pericak-Vance M A
Linkage of Charcot-Marie-Tooth neuropathy type 1a to chromosome 17.
Experimental neurology 1989;104(2):186-9.
1989: Alberts M J; Roses A D
Myotonic muscular dystrophy.
Neurologic clinics 1989;7(1):1-8.
1989: Siddique T; Phillips K; Betz H; Grenningloh G; Warner K; Hung W Y; Laing N; Roses A D
RFLPs of the gene for the human glycine receptor on the X-chromosome.
Nucleic acids research 1989;17(4):1785.
1989: Dawson D V; Roses A D; Pericak-Vance M A; Kaplan E B; Elston R C; Haynes C S; Gaskell P C; Heyman A; Clark C M; Earl N L
Sib-pair linkage analysis in late onset Alzheimer's disease.
Progress in clinical and biological research 1989;317():223-8.
1989: Roses A D; Pericak-Vance M A; Yamaoka L; Haynes C; Speer M; Gaskell P; Hung W Y; Clark C M; Heyman A; Trofatter J
Linkage studies in familial Alzheimer's disease.
Progress in clinical and biological research 1989;317():201-15.
1988: Johnson K; Nimmo E; Jones P; Weiss M; Savontaus M L; Anvret M; Bartlett R; Roses A; Shaw D; Harper P S
Segregation of linked probes to myotonic dystrophy in a family demonstrating that 152 and APOC2 are on the same side of DM on 19q.
Human genetics 1988;80(4):379-81.
1988: Payne C S; Roses A D
The molecular genetic revolution. Its impact on clinical neurology.
Archives of neurology 1988;45(12):1366-76.
1988: Walker A P; Bartlett R J; Laing N G; Siddique T; Yamaoka L H; Chen J C; Hung W Y; Roses A D
RFLP for Duchenne muscular dystrophy cDNA clone 30-2.
Nucleic acids research 1988;16(18):9072.
1988: Walker A P; Bartlett R J; Yamaoka L H; Secore S L; Lee J E; Gilbert J; Herbstreith M; Pericak-Vance M A; Hung W Y; Roses A D
A Bgl II polymorphism detected by LDR152 [D19S19].
Nucleic acids research 1988;16(18):9063.
1988: Siddique T; McKinney R; Hung W Y; Bartlett R J; Bruns G; Mohandas T K; Ropers H H; Wilfert C; Roses A D
The poliovirus sensitivity (PVS) gene is on chromosome 19q12----q13.2.
Genomics 1988;3(2):156-60.
1988: Speer M C; Pericak-Vance M A; Yamaoka L H; Koh J; Hung W Y; Gaskell P C; Vance J M; Bartlett R J; Roses A D
Prenatal diagnosis using deletion studies in Duchenne muscular dystrophy.
Prenatal diagnosis 1988;8(6):427-37.
1988: Laing N G; Siddique T; Bartlett R J; Yamaoka L H; Chen J C; Walker A P; Hung W Y; Roses A D
RFLP for Duchenne muscular dystrophy cDNA clone 44-1.
Nucleic acids research 1988;16(14B):7209.
1988: Roses A D
Mutants in Duchenne muscular dystrophy. Implications for prevention.
Archives of neurology 1988;45(1):84-5.
1988: Gilchrist J M; Pericak-Vance M; Silverman L; Roses A D
Clinical and genetic investigation in autosomal dominant limb-girdle muscular dystrophy.
Neurology 1988;38(1):5-9.
1988: Schmechel D E; Goldgaber D; Burkhart D S; Gilbert J R; Gajdusek D C; Roses A D
Cellular localization of messenger RNA encoding amyloid-beta-protein in normal tissue and in Alzheimer disease.
Alzheimer disease and associated disorders 1988;2(2):96-111.
1988: Siddique T; Bartlett R; Pericak-Vance M; Yamaoka L; Koh J; Chen J; Hung W Y; Kandt R; Roses A D
Update on the molecular genetics of Duchenne muscular dystrophy.
Australian paediatric journal 1988;24 Suppl 1():9-14.
1988: Roses A D; Pericak-Vance M A; Bartlett R J; Yamaoka L H; Lee J E; Koh J; Chen J C; Gilbert J R; Ross D A; Herbstreith M H
Myotonic dystrophy: update on progress to define the gene.
Australian paediatric journal 1988;24 Suppl 1():66-9.
1987: Vance J M; Pericak-Vance M A; Bowman M H; Payne C S; Fredane L; Siddique T; Roses A D; Massey E W
Chorea-acanthocytosis: a report of three new families and implications for genetic counselling.
American journal of medical genetics 1987;28(2):403-10.
1987: Rozear M P; Pericak-Vance M A; Fischbeck K; Stajich J M; Gaskell P C; Krendel D A; Graham D G; Dawson D V; Roses A D
Hereditary motor and sensory neuropathy, X-linked: a half century follow-up.
Neurology 1987;37(9):1460-5.
1987: Diehl S R; Boehnke M; Collins F S; Erickson R P; Karolyi I J; Ploughman L M; Pericak-Vance M A; Aylsworth A S; Roses A D
Linkage analysis of peripheral neurofibromatosis to DNA markers on chromosome 8.
Journal of medical genetics 1987;24(9):532-4.
1987: Pericak-Vance M A; Yamaoka L H; Vance J M; Aylsworth A S; Rossenwasser G O; Gaskell P C; Alberts M J; Hung W Y; Haynes C; Roses A D
Linkage studies in peripheral neurofibromatosis.
Journal of medical genetics 1987;24(9):530-2.
1987: Lanman J T; Pericak-Vance M A; Bartlett R J; Chen J C; Yamaoka L; Koh J; Speer M C; Hung W Y; Roses A D
Familial inheritance of a DXS164 deletion mutation from a heterozygous female.
American journal of human genetics 1987;41(2):138-44.
1987: Morrison M R; Pardue S; Maschoff K; Griffin W S; White C L; Gilbert J; Roses A
Brain messenger RNA levels and ribonuclease activity in Alzheimer's disease.
Biochemical Society transactions 1987;15(1):133-4.
1987: Olanow C W; Wechsler A S; Sirotkin-Roses M; Stajich J; Roses A D
Thymectomy as primary therapy in myasthenia gravis.
Annals of the New York Academy of Sciences 1987;505():595-606.
1986: Kunkel L M; Hejtmancik J F; Caskey C T; Speer A; Monaco A P; Middlesworth W; Colletti C A; Bertelson C; Müller U; Bresnan M; Shapiro F; Tantravahi U; Speer J; Latt S A; Bartlett R; Pericak-Vance M A; Roses A D; Thompson M W; Ray P N; Worton R G; Fischbeck K H; Gallano P; Coulon M; Duros C; Boue J; Junien C; Chelly J; Hamard G; Jeanpierre M; Lambert M; Kaplan J C; Emery A; Dorkins H; McGlade S; Davies K E; Boehm C; Arveiler B; Lemaire C; Morgan G J; Denton M J; Amos J; Bobrow M; Benham F; Boswinkel E; Cole C; Dubowitz V; Hart K; Hodgson S; Johnson L; Walker A; Roncuzzi L; Ferlini A; Nobile C; Romeo G; Wilcox D E; Affara N A; Ferguson-Smith M A; Lindolf M; Kaariainen H; de la Chapelle A; Ionasescu V; Searby C; Ionasescu R; Bakker E; van Ommen G J; Pearson P L; Greenberg C R; Hamerton J L; Wrogemann K; Doherty R A; Polakowska R; Hyser C; Quirk S; Thomas N; Harper J F; Darras B T; Francke U
Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy.
Nature 1986;322(6074):73-7.
1985: Monaco A P; Bertelson C J; Middlesworth W; Colletti C A; Aldridge J; Fischbeck K H; Bartlett R; Pericak-Vance M A; Roses A D; Kunkel L M
Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment.
Nature 1985;316(6031):842-5.
1985: Roses A D
Myotonic muscular dystrophy. From clinical description to molecular genetics.
Archives of internal medicine 1985;145(8):1487-92.
1983: Roses A D; Pericak-Vance M A; Yamaoka L H; Stubblefield E; Stajich J; Vance J M; Roses M J; Carter D B
Recombinant DNA strategies in genetic neurological diseases.
Muscle & nerve 1983;6(5):339-55.
1983: Lane R J; Robinow M; Roses A D
The genetic status of mothers of isolated cases of Duchenne muscular dystrophy.
Journal of medical genetics 1983;20(1):1-11.
1981: Lane R J; Roses A D
Variation of serum creatine kinase levels with age in normal females: implications for genetic counselling in Duchenne muscular dystrophy.
Clinica chimica acta; international journal of clinical chemistry 1981;113(1):75-86.
1977: Roses A D; Roses M J; Metcalf B S; Hull K L; Nicholson G A; Hartwig G B; Roe C R
Pedigree testing in Duchenne muscular dystrophy.
Annals of neurology 1977;2(4):271-8.
1977: Roses A D; Roses M J; Nicholson G A; Roe C R
Lactate dehydrogenase isoenzyme in detecting carriers of Duchenne muscular dystrophy.
Neurology 1977;27(5):414-21.
1976: Roses A D
Identification of Duchenne muscular dystrophy carriers.
Lancet 1976;2(7986):636.

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