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Edward Rosloniec

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Masaru Kimata; Linda K Myers; Edward F Rosloniec; John M Stuart; David D Brand; Monica L Brown; David L Cullins; Andrew H Kang
Characterization of inhibitory T cells induced by an analog of type II collagen in an HLA-DR1 humanized mouse model of autoimmune arthritis.
Zhaohui Qian; Kary A Latham; Karen B Whittington; David C Miller; David Douglass Brand; Edward F Rosloniec
An autoantigen-specific, highly restricted T cell repertoire infiltrates the arthritic joints of mice in an HLA-DR1 humanized mouse model of autoimmune arthritis.
Edward F Rosloniec; Michael Cremer; Andrew H Kang; Linda K Myers; David Douglass Brand
Collagen-induced arthritis.

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2012: Masaru Kimata; Linda K Myers; Edward F Rosloniec; John M Stuart; David D Brand; Monica L Brown; David L Cullins; Andrew H Kang
Characterization of inhibitory T cells induced by an analog of type II collagen in an HLA-DR1 humanized mouse model of autoimmune arthritis.
Arthritis research & therapy 2012;14(3):R107.
2010: Zhaohui Qian; Kary A Latham; Karen B Whittington; David C Miller; David Douglass Brand; Edward F Rosloniec
An autoantigen-specific, highly restricted T cell repertoire infiltrates the arthritic joints of mice in an HLA-DR1 humanized mouse model of autoimmune arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(1):110-8.
2010: Edward F Rosloniec; Michael Cremer; Andrew H Kang; Linda K Myers; David Douglass Brand
Collagen-induced arthritis.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2010;Chapter 15():Unit 15.5.1-25.
2008: Jianya Huan; Laurie J Kaler; Jeff Mooney; Sandhya Subramanian; Corwyn Hopke; Arthur Vandenbark; Edward F Rosloniec; Gregory G Burrows; Halina Offner
MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(2):1249-57.
2007: David Douglass Brand; Kary A Latham; Edward F Rosloniec
Collagen-induced arthritis.
Nature protocols 2007;2(5):1269-75.
2006: Edward F Rosloniec; Tilmann Brandstetter; Sigmar Leyer; Franz-Werner Schwaiger; Zoltan A Nagy
Second-generation peptidomimetic inhibitors of antigen presentation effectively treat autoimmune diseases in HLA-DR-transgenic mouse models.
Journal of autoimmunity 2006;27(3):182-95.
2006: Edward F Rosloniec; Robert A Ivey; Karen B Whittington; Andrew H Kang; Hee-Won Park
Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3884-92.
2006: Yoshihiko Sakurai; David Douglass Brand; Bo Tang; Edward F Rosloniec; John M Stuart; Andrew H Kang; Linda K Myers
Analog peptides of type II collagen can suppress arthritis in HLA-DR4 (DRB1*0401) transgenic mice.
Arthritis research & therapy 2006;8(5):R150.
2006: Yoshihiko Sakurai; Bo Tang; Edward F Rosloniec; John M Stuart; Andrew H Kang; Linda K Myers
Molecular characterization of an arthritogenic collagen peptide interacting with I-Ar.
Immunology 2006;117(1):136-42.
2005: Michael T Falta; Andrew P Fontenot; Edward F Rosloniec; Frances Crawford; Christina L Roark; Jerome R Bill; Philippa Marrack; John Kappler; Brian L Kotzin
Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen.
Arthritis and rheumatism 2005;52(6):1885-96.
2005: Kary A Latham; Karen B Whittington; Ruohong Zhou; Zhaohui Qian; Edward F Rosloniec
Ex vivo characterization of the autoimmune T cell response in the HLA-DR1 mouse model of collagen-induced arthritis reveals long-term activation of type II collagen-specific cells and their presence in arthritic joints.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):3978-85.
2004: Linda K Myers; B Tang; David Douglass Brand; Edward F Rosloniec; J M Stuart; Andrew H Kang
Efficacy of modified recombinant type II collagen in modulating autoimmune arthritis.
Arthritis and rheumatism 2004;50(9):3004-11.
2004: Michael A Cremer; Xiu J Ye; Linda K Myers; David Douglass Brand; Edward F Rosloniec; Andrew H Kang
T cell immunity to type II collagen in the biobreeding rat: the identification and characterization of RT1u-restricted T cell epitopes on alpha 1(II).
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1795-801.
2004: Xiaowen He; Edward F Rosloniec; Linda K Myers; William Lewis McColgan; Marina Gumanovskaya; Andrew H Kang; John M Stuart
T cell receptors recognizing type II collagen in HLA-DR-transgenic mice characterized by highly restricted V beta usage.
Arthritis and rheumatism 2004;50(6):1996-2004.
2004: Linda K Myers; Yoshihiko Sakurai; Edward F Rosloniec; John M Stuart; Andrew H Kang
An analog peptide that suppresses collagen-induced arthritis.
The American journal of the medical sciences 2004;327(4):212-6.
2004: Edward F Rosloniec; Karen B Whittington; Xiaowen He; John M Stuart; Andrew H Kang
Collagen-induced arthritis mediated by HLA-DR1 (*0101) and HLA-DR4 (*0401).
The American journal of the medical sciences 2004;327(4):169-79.
2004: David Douglass Brand; Andrew H Kang; Edward F Rosloniec
The mouse model of collagen-induced arthritis.
Methods in molecular medicine 2004;102():295-312.
2003: Kary A Latham; Alex Zamora; Heather Drought; Sandhya Subramanian; Agata Matejuk; Halina Offner; Edward F Rosloniec
Estradiol treatment redirects the isotype of the autoantibody response and prevents the development of autoimmune arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(11):5820-7.
2003: David Douglass Brand; Andrew H Kang; Edward F Rosloniec
Immunopathogenesis of collagen arthritis.
Springer seminars in immunopathology 2003;25(1):3-18.
2002: Linda K Myers; Yoshihiko Sakurai; B Tang; Xiaowen He; Edward F Rosloniec; John M Stuart; Andrew H Kang
Peptide-induced suppression of collagen-induced arthritis in HLA-DR1 transgenic mice.
Arthritis and rheumatism 2002;46(12):3369-77.
2002: Li Zuo; Constance M Cullen; Monica L DeLay; Sherry Thornton; Linda K Myers; Edward F Rosloniec; Gregory P Boivin; Raphael Hirsch
A single-chain class II MHC-IgG3 fusion protein inhibits autoimmune arthritis by induction of antigen-specific hyporesponsiveness.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(5):2554-9.
2002: Edward F Rosloniec; Kary Latham; Yajaira B Guedez
Paradoxical roles of IFN-gamma in models of Th1-mediated autoimmunity.
Arthritis research 2002;4(6):333-6.
2002: David Douglass Brand; Linda K Myers; Karen B Whittington; Kary A Latham; John M Stuart; Andrew H Kang; Edward F Rosloniec
Detection of early changes in autoimmune T cell phenotype and function following intravenous administration of type II collagen in a TCR-transgenic model.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):490-8.
2002: Edward F Rosloniec; Karen B Whittington; Dennis Zaller; Andrew H Kang
HLA-DR1 (DRB1*0101) and DR4 (DRB1*0401) use the same anchor residues for binding an immunodominant peptide derived from human type II collagen.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):253-9.
2001: Y B Guedez; Karen B Whittington; J L Clayton; L A Joosten; F A van de Loo; W B van den Berg; Edward F Rosloniec
Genetic ablation of interferon-gamma up-regulates interleukin-1beta expression and enables the elicitation of collagen-induced arthritis in a nonsusceptible mouse strain.
Arthritis and rheumatism 2001;44(10):2413-24.
2001: Edward F Rosloniec; Michael A Cremer; A Kang; Linda K Myers
Collagen-induced arthritis.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2001;Chapter 15():Unit 15.5.
2001: David Douglass Brand; Karen B Whittington; Edward F Rosloniec
I-Aq and I-Ap bind and present similar antigenic peptides despite differing in their ability to mediate susceptibility to autoimmune arthritis.
Autoimmunity 2001;34(2):133-45.
2000: Linda K Myers; Andrew H Kang; Arnold E Postlethwaite; Edward F Rosloniec; SG Morham; BV Shlopov; Sarita Goorha; Leslie R Ballou
The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis.
Arthritis and rheumatism 2000;43(12):2687-93.
2000: Brian L Kotzin; Michael T Falta; F Crawford; Edward F Rosloniec; Jerome R Bill; Philippa Marrack; John Kappler
Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):291-6.
1999: Marina Gumanovskaya; Linda K Myers; Edward F Rosloniec; John M Stuart; Andrew H Kang
Intravenous tolerization with type II collagen induces interleukin-4-and interleukin-10-producing CD4+ T cells.
Immunology 1999;97(3):466-73.
1998: Linda K Myers; David Douglass Brand; Xiu J Ye; Michael A Cremer; Edward F Rosloniec; Michael Bodo; Johanna Myllyharju; T Helaakoski; Minna Nokelainen; Taina Pihlajaniemi; Kari I Kivirikko; C L Yang; Leena Ala-Kokko; D J Prockop; Holger Notbohm; PP Fietzek; John M Stuart; Andrew H Kang
Characterization of recombinant type II collagen: arthritogenicity and tolerogenicity in DBA/1 mice.
Immunology 1998;95(4):631-9.
1998: Linda K Myers; Bo Tang; Edward F Rosloniec; John M Stuart; Thomas M Chiang; Andrew H Kang
Characterization of a peptide analog of a determinant of type II collagen that suppresses collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3589-95.
1998: Bo Tang; Linda K Myers; Edward F Rosloniec; Karen B Whittington; John M Stuart; Andrew H Kang
Characterization of signal transduction through the TCR-zeta chain following T cell stimulation with analogue peptides of type II collagen 260-267.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3135-42.
1998: Edward F Rosloniec; David Douglass Brand; Linda K Myers; Yukio Esaki; Karen B Whittington; Dennis Zaller; A Woods; John M Stuart; Andrew H Kang
Induction of autoimmune arthritis in HLA-DR4 (DRB1*0401) transgenic mice by immunization with human and bovine type II collagen.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(6):2573-8.
1998: M A Cremer; Edward F Rosloniec; Andrew H Kang
The cartilage collagens: a review of their structure, organization, and role in the pathogenesis of experimental arthritis in animals and in human rheumatic disease.
Journal of molecular medicine (Berlin, Germany) 1998;76(3-4):275-88.
1997: S Kawamura; H Miyahara; Yukio Esaki; Linda K Myers; Edward F Rosloniec; John M Stuart; Andrew H Kang
Restricted TCR V alpha repertoire in the T cell response to a tolerogenic determinant of type II collagen.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(12):6013-8.
1997: Edward F Rosloniec; David Douglass Brand; Linda K Myers; Karen B Whittington; Marina Gumanovskaya; Dennis Zaller; A Woods; D M Altmann; John M Stuart; Andrew H Kang
An HLA-DR1 transgene confers susceptibility to collagen-induced arthritis elicited with human type II collagen.
The Journal of experimental medicine 1997;185(6):1113-22.
1997: Linda K Myers; Edward F Rosloniec; Michael A Cremer; Andrew H Kang
Collagen-induced arthritis, an animal model of autoimmunity.
Life sciences 1997;61(19):1861-78.
1996: David Douglass Brand; Tony N Marion; Linda K Myers; Edward F Rosloniec; W C Watson; John M Stuart; Andrew H Kang
Autoantibodies to murine type II collagen in collagen-induced arthritis: a comparison of susceptible and nonsusceptible strains.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):5178-84.
1996: Edward F Rosloniec; Karen B Whittington; David Douglass Brand; Linda K Myers; John M Stuart
Identification of MHC class II and TCR binding residues in the type II collagen immunodominant determinant mediating collagen-induced arthritis.
Cellular immunology 1996;172(1):21-8.
1996: Leslie R Ballou; Stanley J F Laulederkind; Edward F Rosloniec; Rajendra Raghow
Ceramide signalling and the immune response.
Biochimica et biophysica acta 1996;1301(3):273-87.
1995: Edward F Rosloniec; David Douglass Brand; Karen B Whittington; John M Stuart; M Ciubotaru; E S Ward
Vaccination with a recombinant V alpha domain of a TCR prevents the development of collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(9):4504-11.
1995: H Miyahara; Linda K Myers; Edward F Rosloniec; David Douglass Brand; J M Seyer; John M Stuart; Andrew H Kang
Identification and characterization of a major tolerogenic T-cell epitope of type II collagen that suppresses arthritis in B10.RIII mice.
Immunology 1995;86(1):110-5.
1994: David Douglass Brand; Linda K Myers; K Terato; Karen B Whittington; John M Stuart; Andrew H Kang; Edward F Rosloniec
Characterization of the T cell determinants in the induction of autoimmune arthritis by bovine alpha 1(II)-CB11 in H-2q mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(6):3088-97.
1993: Linda K Myers; Edward F Rosloniec; J M Seyer; John M Stuart; Andrew H Kang
A synthetic peptide analogue of a determinant of type II collagen prevents the onset of collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(10):4652-8.