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Kenneth Ross

Research Profile

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Oligonucleotide Array Sequence Analysis

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Giovanni Roti; Angela H Su; Jon C Aster; Stephen C Blacklow; Anne Carlton; Andrew L Kung; Michele Markstein; Kostandin Pajcini; Warren S Pear; Norbert Perrimon; Kenneth N Ross; Kimberly Stegmaier
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer.
Versha Banerji; Kwan T Chow; Daniel J DeAngelo; Stacey M Frumm; Ilene Galinsky; Cynthia K Hahn; William C Hahn; Haig Inguilizian; Rose M Kakoza; Andrew L Kung; Loretta S Li; Kenneth N Ross; Linda Ross; Giovanni Roti; Anna C Schinzel; Gabriela Alexe; Jon C Aster; Richard M Stone; Nicola Tolliday; Kimberly Stegmaier
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.
Cynthia K Hahn; Jacob E Berchuck; Kenneth N Ross; Rose M Kakoza; Karl Clauser; Anna C Schinzel; Linda Ross; Ilene Galinsky; Tina N Davis; Serena J Silver; David E Root; Richard M Stone; Daniel J DeAngelo; Martin Carroll; William C Hahn; Steven A Carr; Todd R Golub; Andrew L Kung; Kimberly Stegmaier
Proteomic and genetic approaches identify Syk as an AML target.

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All Publications

2013: Giovanni Roti; Angela H Su; Jon C Aster; Stephen C Blacklow; Anne Carlton; Andrew L Kung; Michele Markstein; Kostandin Pajcini; Warren S Pear; Norbert Perrimon; Kenneth N Ross; Kimberly Stegmaier
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer.
Cancer cell 2013;23(3):390-405.
2012: Versha Banerji; Kwan T Chow; Daniel J DeAngelo; Stacey M Frumm; Ilene Galinsky; Cynthia K Hahn; William C Hahn; Haig Inguilizian; Rose M Kakoza; Andrew L Kung; Loretta S Li; Kenneth N Ross; Linda Ross; Giovanni Roti; Anna C Schinzel; Gabriela Alexe; Jon C Aster; Richard M Stone; Nicola Tolliday; Kimberly Stegmaier
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.
The Journal of clinical investigation 2012;122(3):935-47.
2009: Cynthia K Hahn; Jacob E Berchuck; Kenneth N Ross; Rose M Kakoza; Karl Clauser; Anna C Schinzel; Linda Ross; Ilene Galinsky; Tina N Davis; Serena J Silver; David E Root; Richard M Stone; Daniel J DeAngelo; Martin Carroll; William C Hahn; Steven A Carr; Todd R Golub; Andrew L Kung; Kimberly Stegmaier
Proteomic and genetic approaches identify Syk as an AML target.
Cancer cell 2009;16(4):281-94.
2009: Steven M Corsello; Giovanni Roti; Kenneth N Ross; Kwan T Chow; Ilene Galinsky; Daniel J DeAngelo; Richard M Stone; Andrew L Kung; Todd R Golub; Kimberly Stegmaier
Identification of AML1-ETO modulators by chemical genomics.
Blood 2009;113(24):6193-205.
2008: Cynthia K Hahn; Kenneth N Ross; Ian M Warrington; Ralph Mazitschek; Cindy M Kanegai; Renee D Wright; Andrew L Kung; Todd R Golub; Kimberly Stegmaier
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9751-6.
2007: Kimberly Stegmaier; Jenny S Wong; Kenneth N Ross; Kwan T Chow; David Peck; Renee D Wright; Stephen L Lessnick; Andrew L Kung; Todd R Golub
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.
PLoS medicine 2007;4(4):e122.
2006: Haley Hieronymus; Justin Lamb; Kenneth N Ross; Xiao P Peng; Cristina Clement; Anna Rodina; Maria Nieto; Jinyan Du; Kimberly Stegmaier; Srilakshmi M Raj; Katherine N Maloney; Jon Clardy; William C Hahn; Gabriela Chiosis; Todd R Golub
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.
Cancer cell 2006;10(4):321-30.
2006: Justin Lamb; Emily D Crawford; David Peck; Joshua W Modell; Irene C Blat; Matthew J Wrobel; Jim Lerner; Jean-Philippe Brunet; Aravind Subramanian; Kenneth N Ross; Michael Reich; Haley Hieronymus; Guo Wei; Scott A Armstrong; Stephen Haggarty; Paul A Clemons; Ru Wei; Steven A Carr; Eric S Lander; Todd R Golub
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
Science (New York, N.Y.) 2006;313(5795):1929-35.
2006: David Peck; Emily D Crawford; Kenneth N Ross; Kimberly Stegmaier; Todd R Golub; Justin Lamb
A method for high-throughput gene expression signature analysis.
Genome biology 2006;7(7):R61.
2005: Kimberly Stegmaier; Steven M Corsello; Kenneth N Ross; Jenny S Wong; Daniel J DeAngelo; Todd R Golub
Gefitinib induces myeloid differentiation of acute myeloid leukemia.
Blood 2005;106(8):2841-8.
2005: Patricia Dahia; Kenneth N Ross; Matthew E Wright; César Y Hayashida; Sandro Santagata; Marta Barontini; Andrew L Kung; Gabriela Sanso; James F Powers; Arthur S Tischler; Richard A Hodin; Shannon Heitritter; Francis Moore; Robert Dluhy; Julie Ann Sosa; I Tolgay Ocal; Diana E Benn; Deborah J Marsh; Bruce G Robinson; Katherine Schneider; Judy E Garber; Seth M Arum; Marta Korbonits; Ashley Grossman; Pascal Pigny; sergio toledo; Vania Nosé; Cheng Li; Charles D Stiles
A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas.
PLoS genetics 2005;1(1):72-80.
2004: Kimberly Stegmaier; Kenneth N Ross; Sierra A Colavito; Shawn O'Malley; Brent R Stockwell; Todd R Golub
Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation.
Nature genetics 2004;36(3):257-63.
2003: Sridhar Ramaswamy; Kenneth N Ross; Eric S Lander; Todd R Golub
A molecular signature of metastasis in primary solid tumors.
Nature genetics 2003;33(1):49-54.
2002: Margaret A Shipp; Kenneth N Ross; Pablo Tamayo; Andrew P Weng; Jeffery L Kutok; Ricardo Aguiar; Michelle Gaasenbeek; Michael Angelo; Michael Reich; Geraldine S Pinkus; Tane S Ray; Margaret A Koval; Kim W Last; Andrew Norton; T Andrew Lister; Jill P Mesirov; Donna Neuberg; Eric S Lander; Jon C Aster; Todd R Golub
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning.
Nature medicine 2002;8(1):68-74.