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Edmund Rossi

Research Profile

Chemicals & Drugs

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TOP 3
Edmund A Rossi; Thomas M Cardillo; Chien-Hsing Chang; David M Goldenberg
Optimization of multivalent bispecific antibodies and immunocytokines with improved in vivo properties.
Donglin Liu; Edmund A Rossi; Thomas M Cardillo; Chien-Hsing Chang; David M Goldenberg
Interferon-λ1 Linked to a Stabilized Dimer of Fab Potently Enhances both Antitumor and Antiviral Activities in Targeted Cells.
Chien-Hsing Chang; Tina Falkeborn; David M Goldenberg; Jorma Hinkula; Rongxiu Li; Meiyu Loo; Edmund A Rossi; Thomas M Cardillo; Britta Wahren
A novel class of anti-HIV agents with multiple copies of enfuvirtide enhances inhibition of viral replication and cellular transmission in vitro.

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All Publications

2013: Edmund A Rossi; Thomas M Cardillo; Chien-Hsing Chang; David M Goldenberg
Optimization of multivalent bispecific antibodies and immunocytokines with improved in vivo properties.
Bioconjugate chemistry 2013;24(1):63-71.
2013: Donglin Liu; Edmund A Rossi; Thomas M Cardillo; Chien-Hsing Chang; David M Goldenberg
Interferon-λ1 Linked to a Stabilized Dimer of Fab Potently Enhances both Antitumor and Antiviral Activities in Targeted Cells.
PloS one 2013;8(5):e63940.
2012: Chien-Hsing Chang; Tina Falkeborn; David M Goldenberg; Jorma Hinkula; Rongxiu Li; Meiyu Loo; Edmund A Rossi; Thomas M Cardillo; Britta Wahren
A novel class of anti-HIV agents with multiple copies of enfuvirtide enhances inhibition of viral replication and cellular transmission in vitro.
PloS one 2012;7(7):e41235.
2011: Habibe Karacay; Robert M Sharkey; William J McBride; Edmund A Rossi; Chien-Hsing Chang; David M Goldenberg
Optimization of hapten-peptide labeling for pretargeted immunoPET of bispecific antibody using generator-produced 68Ga.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(4):555-9.
2010: William J McBride; Christopher A D'Souza; Robert M Sharkey; Habibe Karacay; Edmund A Rossi; Chien-Hsing Chang; David M Goldenberg
Improved 18F labeling of peptides with a fluoride-aluminum-chelate complex.
Bioconjugate chemistry 2010;21(7):1331-40.
2009: Habibe Karacay; Robert M Sharkey; David V Gold; Dan R Ragland; William J McBride; Edmund A Rossi; Chien-Hsing Chang; David M Goldenberg
Pretargeted radioimmunotherapy of pancreatic cancer xenografts: TF10-90Y-IMP-288 alone and combined with gemcitabine.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(12):2008-16.
2008: Robert M Sharkey; Habibe Karacay; Shankar Vallabhajosula; William J McBride; Edmund A Rossi; Chien-Hsing Chang; Stanley J Goldsmith; David M Goldenberg
Metastatic human colonic carcinoma: molecular imaging with pretargeted SPECT and PET in a mouse model.
Radiology 2008;246(2):497-507.
2007: Pierre-Yves Brard; Habibe Karacay; Rhona Stein; Robert M Sharkey; M Jules Mattes; Chien-Hsing Chang; Edmund A Rossi; William J McBride; David M Goldenberg
A divalent hapten-peptide induces apoptosis in human non hodgkin lymphoma cell lines targeted by anti-CD20xanti-hapten bispecific antibodies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(18 Pt 2):5564s-5571s.
2006: William J McBride; Pat Zanzonico; Robert M Sharkey; Carl Norén; Habibe Karacay; Edmund A Rossi; Michele J Losman; Pierre-Yves Brard; Chien-Hsing Chang; Steven M Larson; David M Goldenberg
Bispecific antibody pretargeting PET (immunoPET) with an 124I-labeled hapten-peptide.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(10):1678-88.
2005: Habibe Karacay; Pierre-Yves Brard; Robert M Sharkey; Chien-Hsing Chang; Edmund A Rossi; William J McBride; Dan R Ragland; Ivan D Horak; David M Goldenberg
Therapeutic advantage of pretargeted radioimmunotherapy using a recombinant bispecific antibody in a human colon cancer xenograft.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7879-85.
2005: Edmund A Rossi; Chien-Hsing Chang; Michele J Losman; Robert M Sharkey; Habibe Karacay; William McBride; Thomas M Cardillo; Hans J Hansen; Zhengxing Qu; Ivan D Horak; David M Goldenberg
Pretargeting of carcinoembryonic antigen-expressing cancers with a trivalent bispecific fusion protein produced in myeloma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(19 Pt 2):7122s-7129s.
2005: Robert M Sharkey; Habibe Karacay; Thomas M Cardillo; Chien-Hsing Chang; William J McBride; Edmund A Rossi; Ivan D Horak; David M Goldenberg
Improving the delivery of radionuclides for imaging and therapy of cancer using pretargeting methods.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(19 Pt 2):7109s-7121s.
2004: Gary L Griffiths; Chien-Hsing Chang; William J McBride; Edmund A Rossi; Agatha Sheerin; German R Tejada; Habibe Karacay; Robert M Sharkey; Ivan D Horak; Hans J Hansen; David M Goldenberg
Reagents and methods for PET using bispecific antibody pretargeting and 68Ga-radiolabeled bivalent hapten-peptide-chelate conjugates.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(1):30-9.
2003: Robert M Sharkey; Habibe Karacay; Heidi Richel; William J McBride; Edmund A Rossi; Ken Chang; Dion Yeldell; Gary L Griffiths; Hans J Hansen; David M Goldenberg
Optimizing bispecific antibody pretargeting for use in radioimmunotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 2):3897S-913S.
2003: Edmund A Rossi; Robert M Sharkey; William McBride; Habibe Karacay; Li Zeng; Hans J Hansen; David M Goldenberg; Chien-Hsing Chang
Development of new multivalent-bispecific agents for pretargeting tumor localization and therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 2):3886S-96S.
2003: David M Goldenberg; Chien-Hsing Chang; Robert M Sharkey; Edmund A Rossi; Habibe Karacay; William McBride; Hans J Hansen; Jean-François Chatal; Jacques Barbet
Radioimmunotherapy: is avidin-biotin pretargeting the preferred choice among pretargeting methods?
European journal of nuclear medicine and molecular imaging 2003;30(5):777-80.
2002: Chien-Hsing Chang; Robert M Sharkey; Edmund A Rossi; Habibe Karacay; William McBride; Hans J Hansen; Jean-François Chatal; Jacques Barbet; David M Goldenberg
Molecular advances in pretargeting radioimunotherapy with bispecific antibodies.
Molecular cancer therapeutics 2002;1(7):553-63.

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