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Jürgen Roth

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Valerie Le Fourn; Yangsin Lee; Sujin Park; Jin Won Cho; Katarina Gaplovska-Kysela; Bruno Guhl; Insook Jang; Christian Zuber; Jürgen Roth
Large protein complexes retained in the ER are dislocated by non-COPII vesicles and degraded by selective autophagy.
Tania Torossi; Bruno Guhl; Jürgen Roth; Martin Ziak
Endomannosidase undergoes phosphorylation in the Golgi apparatus.
Kiyoko Hirano; Bruno Guhl; Jürgen Roth; Martin Ziak
A cell culture system for the induction of Mallory bodies: Mallory bodies and aggresomes represent different types of inclusion bodies.

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2013: Valerie Le Fourn; Yangsin Lee; Sujin Park; Jin Won Cho; Katarina Gaplovska-Kysela; Bruno Guhl; Insook Jang; Christian Zuber; Jürgen Roth
Large protein complexes retained in the ER are dislocated by non-COPII vesicles and degraded by selective autophagy.
Cellular and molecular life sciences : CMLS 2013;70(11):1985-2002.
2010: Tania Torossi; Bruno Guhl; Jürgen Roth; Martin Ziak
Endomannosidase undergoes phosphorylation in the Golgi apparatus.
Glycobiology 2010;20(1):55-61.
2009: Kiyoko Hirano; Bruno Guhl; Jürgen Roth; Martin Ziak
A cell culture system for the induction of Mallory bodies: Mallory bodies and aggresomes represent different types of inclusion bodies.
Histochemistry and cell biology 2009;132(3):293-304.
2009: Manfred G Ismair; Stephanie Häusler; Claudia A Stuermer; Christelle Guyot; Peter J Meier Abt; Jürgen Roth; Bruno Stieger
ABC-transporters are localized in caveolin-1-positive and reggie-1-negative and reggie-2-negative microdomains of the canalicular membrane in rat hepatocytes.
Hepatology (Baltimore, Md.) 2009;49(5):1673-82.
2009: V Le Fourn; Katarina Gaplovska-Kysela; Bruno Guhl; R Santimaria; Christian Zuber; Jürgen Roth
Basal autophagy is involved in the degradation of the ERAD component EDEM1.
Cellular and molecular life sciences : CMLS 2009;66(8):1434-45.
2008: Jürgen Roth; Gary Hin-Fai Yam; Jingyu Fan; Kiyoko Hirano; Katarina Gaplovska-Kysela; Valerie Le Fourn; Bruno Guhl; Roger Santimaria; Tania Torossi; Martin Ziak; Christian Zuber
Protein quality control: the who's who, the where's and therapeutic escapes.
Histochemistry and cell biology 2008;129(2):163-77.
2008: Jürgen Roth; H Dariush Fahimi; Detlev Drenckhahn
Celebration of the 50th anniversary of publication of Histochemistry and Cell Biology.
Histochemistry and cell biology 2008;129(1):1-3.
2007: Christian Zuber; Douglas J Taatjes; Jürgen Roth
Recent progress in histochemistry.
Histochemistry and cell biology 2007;128(6):557-94.
2007: Gary Hin-Fai Yam; Jürgen Roth; Christian Zuber
4-Phenylbutyrate rescues trafficking incompetent mutant alpha-galactosidase A without restoring its functionality.
Biochemical and biophysical research communications 2007;360(2):375-80.
2007: Jing-Yu Fan; Jürgen Roth; Christian Zuber
Expression of mutant Ins2C96Y results in enhanced tubule formation causing enlargement of pre-Golgi intermediates of CHO cells.
Histochemistry and cell biology 2007;128(2):161-73.
2007: T Torossi; Jürgen Roth; Martin Ziak
A single tryptophan residue of endomannosidase is crucial for Golgi localization and in vivo activity.
Cellular and molecular life sciences : CMLS 2007;64(14):1881-9.
2007: Gary Hin-Fai Yam; Katarina Gaplovska-Kysela; Christian Zuber; Jürgen Roth
Sodium 4-phenylbutyrate acts as a chemical chaperone on misfolded myocilin to rescue cells from endoplasmic reticulum stress and apoptosis.
Investigative ophthalmology & visual science 2007;48(4):1683-90.
2007: Christian Zuber; James H Cormier; Bruno Guhl; Roger Santimaria; Daniel N Hebert; Jürgen Roth
EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4407-12.
2007: Gary Hin-Fai Yam; Katarina Gaplovska-Kysela; Christian Zuber; Jürgen Roth
Aggregated myocilin induces russell bodies and causes apoptosis: implications for the pathogenesis of myocilin-caused primary open-angle glaucoma.
The American journal of pathology 2007;170(1):100-9.
2006: T Torossi; Jing-Yu Fan; K Sauter-Etter; Jürgen Roth; Martin Ziak
Endomannosidase processes oligosaccharides of alpha1-antitrypsin and its naturally occurring genetic variants in the Golgi apparatus.
Cellular and molecular life sciences : CMLS 2006;63(16):1923-32.
2006: Gary Hin-Fai Yam; Nils U Bosshard; Christian Zuber; Beat Steinmann; Jürgen Roth
Pharmacological chaperone corrects lysosomal storage in Fabry disease caused by trafficking-incompetent variants.
American journal of physiology. Cell physiology 2006;290(4):C1076-82.
2005: Christian Zuber; Jingyu Fan; Bruno Guhl; Jürgen Roth
Applications of immunogold labeling in ultrastructural pathology.
Ultrastructural pathology 2005;29(3-4):319-30.
2005: Gary Hin-Fai Yam; Christian Zuber; Jürgen Roth
A synthetic chaperone corrects the trafficking defect and disease phenotype in a protein misfolding disorder.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(1):12-8.
2004: Christian Zuber; Jing-Yu Fan; Bruno Guhl; Jürgen Roth
Misfolded proinsulin accumulates in expanded pre-Golgi intermediates and endoplasmic reticulum subdomains in pancreatic beta cells of Akita mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(7):917-9.
2003: Jing-Yu Fan; Jürgen Roth; Christian Zuber
Ultrastructural analysis of transitional endoplasmic reticulum and pre-Golgi intermediates: a highway for cars and trucks.
Histochemistry and cell biology 2003;120(6):455-63.
2003: Christian Zuber; James C Paulson; Valeriu Toma; Harry C Winter; Irwin J Goldstein; Jürgen Roth
Spatiotemporal expression patterns of sialoglycoconjugates during nephron morphogenesis and their regional and cell type-specific distribution in adult rat kidney.
Histochemistry and cell biology 2003;120(2):143-60.
2003: Kiyoko Hirano; Christian Zuber; Jürgen Roth; Martin Ziak
The proteasome is involved in the degradation of different aquaporin-2 mutants causing nephrogenic diabetes insipidus.
The American journal of pathology 2003;163(1):111-20.
2003: Jürgen Roth; Martin Ziak; Christian Zuber
The role of glucosidase II and endomannosidase in glucose trimming of asparagine-linked oligosaccharides.
Biochimie 2003;85(3-4):287-94.
2002: Aurel Perren; Andre Barghorn; Sonja Schmid; Parvin Saremaslani; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Absence of somatic SDHD mutations in sporadic neuroendocrine tumors and detection of two germline variants in paraganglioma patients.
Oncogene 2002;21(49):7605-8.
2002: Martin Ziak; Mirjam Meier; Ilse Novak-Hofer; Jürgen Roth
Ceruloplasmin carries the anionic glycan oligo/poly alpha2,8 deaminoneuraminic acid.
Biochemical and biophysical research communications 2002;295(3):597-602.
2002: Jianming Zhao; Jürgen Roth; Beata Bode-Lesniewska; Madeleine Pfaltz; Philipp U Heitz; Paul Komminoth
Combined comparative genomic hybridization and genomic microarray for detection of gene amplifications in pulmonary artery intimal sarcomas and adrenocortical tumors.
Genes, chromosomes & cancer 2002;34(1):48-57.
2002: Jürgen Roth; Christian Zuber; Bruno Guhl; Jing-Yu Fan; Martin Ziak
The importance of trimming reactions on asparagine-linked oligosaccharides for protein quality control.
Histochemistry and cell biology 2002;117(2):159-69.
2002: Jürgen Roth
Protein N-glycosylation along the secretory pathway: relationship to organelle topography and function, protein quality control, and cell interactions.
Chemical reviews 2002;102(2):285-303.
2002: Kiyoko Hirano; Jürgen Roth; Christian Zuber; Martin Ziak
Expression of a mutant ER-retained polytope membrane protein in cultured rat hepatocytes results in Mallory body formation.
Histochemistry and cell biology 2002;117(1):41-53.
2001: Jianming Zhao; Holger Moch; Alexander Scheidweiler; A Baer; A A Schäffer; Ernst J M Speel; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Genomic imbalances in the progression of endocrine pancreatic tumors.
Genes, chromosomes & cancer 2001;32(4):364-72.
2001: Christian Zuber; Jing-Yu Fan; Bruno Guhl; A Parodi; John H Fessler; C Parker; Jürgen Roth
Immunolocalization of UDP-glucose:glycoprotein glucosyltransferase indicates involvement of pre-Golgi intermediates in protein quality control.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10710-5.
2001: Valeriu Toma; Christian Zuber; Harry C Winter; Irwin J Goldstein; Jürgen Roth
Application of a lectin from the mushroom Polysporus squamosus for the histochemical detection of the NeuAcalpha2,6Galbeta1,4Glc/GlcNAc sequence of N-linked oligosaccharides: a comparison with the Sambucus nigra lectin.
Histochemistry and cell biology 2001;116(2):183-93.
2001: Andre Barghorn; Paul Komminoth; D Bachmann; K Rütimann; Parvin Saremaslani; S Muletta-Feurer; Aurel Perren; Jürgen Roth; Philipp U Heitz; Ernst J M Speel
Deletion at 3p25.3-p23 is frequently encountered in endocrine pancreatic tumours and is associated with metastatic progression.
The Journal of pathology 2001;194(4):451-8.
2001: Ernst J M Speel; Alexander Scheidweiler; Jianming Zhao; Christian M Matter; Parvin Saremaslani; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Genetic evidence for early divergence of small functioning and nonfunctioning endocrine pancreatic tumors: gain of 9Q34 is an early event in insulinomas.
Cancer research 2001;61(13):5186-92.
2001: Hilde Dannenberg; Ronald R de Krijger; J Zhao; Ernst J M Speel; Parvin Saremaslani; Winand N M Dinjens; Wolter J Mooi; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Differential loss of chromosome 11q in familial and sporadic parasympathetic paragangliomas detected by comparative genomic hybridization.
The American journal of pathology 2001;158(6):1937-42.
2001: Andre Barghorn; Ernst J M Speel; B Farspour; Parvin Saremaslani; Sonja Schmid; Aurel Perren; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Putative tumor suppressor loci at 6q22 and 6q23-q24 are involved in the malignant progression of sporadic endocrine pancreatic tumors.
The American journal of pathology 2001;158(6):1903-11.
2001: Martin Ziak; Mirjam Meier; K S Etter; Jürgen Roth
Two isoforms of trimming glucosidase II exist in mammalian tissues and cell lines but not in yeast and insect cells.
Biochemical and biophysical research communications 2001;280(1):363-7.
2000: Z Dong; Christian Zuber; MJ Spiro; Robert Spiro; Jürgen Roth
Immunohistochemical evaluation of endomannosidase distribution in rat tissues: evidence for cell type-specific expression.
Histochemistry and cell biology 2000;114(6):461-7.
2000: Christian Zuber; MJ Spiro; Bruno Guhl; Robert Spiro; Jürgen Roth
Golgi apparatus immunolocalization of endomannosidase suggests post-endoplasmic reticulum glucose trimming: implications for quality control.
Molecular biology of the cell 2000;11(12):4227-40.
2000: Jianming Zhao; Ronald R de Krijger; D Meier; Ernst J M Speel; Parvin Saremaslani; S Muletta-Feurer; Christian M Matter; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Genomic alterations in well-differentiated gastrointestinal and bronchial neuroendocrine tumors (carcinoids): marked differences indicating diversity in molecular pathogenesis.
The American journal of pathology 2000;157(5):1431-8.
2000: Hilde Dannenberg; Ernst J M Speel; J Zhao; Parvin Saremaslani; Erwin van der Harst; Jürgen Roth; Philipp U Heitz; H Jaap Bonjer; Winand N M Dinjens; Wolter J Mooi; Paul Komminoth; Ronald R de Krijger
Losses of chromosomes 1p and 3q are early genetic events in the development of sporadic pheochromocytomas.
The American journal of pathology 2000;157(2):353-9.
2000: Ronald R de Krijger; Erwin van der Harst; S Muletta-Feurer; Hajo A Bruining; Steven W J Lamberts; Winand N M Dinjens; Jürgen Roth; Philipp U Heitz; Paul Komminoth
RET is expressed but not mutated in extra-adrenal paragangliomas.
The Journal of pathology 2000;191(3):264-8.
2000: Valeriu Toma; Christian Zuber; T Sata; P Komminoth; Seife Hailemariam; J N Eble; Philipp U Heitz; Jürgen Roth
Thomsen-Friedenreich glycotope is expressed in developing and normal kidney but not in renal neoplasms.
Human pathology 2000;31(6):647-55.
2000: Martin Traebert; Jürgen Roth; Jürg Biber; Heini Murer; Brigitte Kaissling
Internalization of proximal tubular type II Na-P(i) cotransporter by PTH: immunogold electron microscopy.
American journal of physiology. Renal physiology 2000;278(1):F148-54.
1999: Ernst J M Speel; J Richter; Holger Moch; C Egenter; Parvin Saremaslani; K Rütimann; Jianming Zhao; Andre Barghorn; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Genetic differences in endocrine pancreatic tumor subtypes detected by comparative genomic hybridization.
The American journal of pathology 1999;155(6):1787-94.
1999: Valeriu Toma; D Hauri; Ulrico Schmid; Daniel Ackermann; Robert Maurer; Göran Alund; Hartmut Knönagel; Marcus Rist; Thomas C Gasser; Guido Sauter; Jürgen Roth
Focal loss of CD44 variant protein expression is related to recurrence in superficial bladder carcinoma.
The American journal of pathology 1999;155(5):1427-32.
1999: Valeriu Toma; Christian Zuber; T Sata; Jürgen Roth
Specialized expression of simple O-glycans along the rat kidney nephron.
Glycobiology 1999;9(11):1191-7.
1999: Jianming Zhao; Ernst J M Speel; S Muletta-Feurer; K Rütimann; Parvin Saremaslani; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Analysis of genomic alterations in sporadic adrenocortical lesions. Gain of chromosome 17 is an early event in adrenocortical tumorigenesis.
The American journal of pathology 1999;155(4):1039-45.
1999: Martin Ziak; Jürgen Roth
Expression of oligo/polyalpha2,8-linked deaminoneuraminic acid and megalin during kidney development and maturation: mutually exclusive distribution with polyalpha2,8-linked N-acetylneuraminic acid of N-CAM.
Histochemistry and cell biology 1999;112(2):169-78.
1999: Valeriu Toma; T Sata; P Vogt; P Komminoth; Philipp U Heitz; Jürgen Roth
Differentiation-related expression of the Thomsen-Friedenreich glycotope in developing human lung and in lung carcinoma: lack of association with malignancy.
Cancer 1999;85(10):2151-9.
1999: Martin Ziak; Mirjam Meier; Jürgen Roth
Megalin in normal tissues and carcinoma cells carries oligo/poly alpha2,8 deaminoneuraminic acid as a unique posttranslational modification.
Glycoconjugate journal 1999;16(3):185-8.
1999: Martin Ziak; D Kerjaschki; M G Farquhar; Jürgen Roth
Identification of megalin as the sole rat kidney sialoglycoprotein containing poly alpha2,8 deaminoneuraminic acid.
Journal of the American Society of Nephrology : JASN 1999;10(2):203-9.
1999: B Görtz; Jürgen Roth; A Krähenmann; Ronald R de Krijger; S Muletta-Feurer; K Rütimann; Parvin Saremaslani; Ernst J M Speel; Philipp U Heitz; Paul Komminoth
Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms.
The American journal of pathology 1999;154(2):429-36.
1999: B Görtz; Jürgen Roth; Ernst J M Speel; A Krähenmann; Ronald R de Krijger; X Matias-Guiu; S Muletta-Feurer; K Rütmann; Parvin Saremaslani; Philipp U Heitz; Paul Komminoth
MEN1 gene mutation analysis of sporadic adrenocortical lesions.
International journal of cancer. Journal international du cancer 1999;80(3):373-9.
1998: Aurel Perren; Jürgen Roth; S Muletta-Feurer; Parvin Saremaslani; Ernst J M Speel; Philipp U Heitz; Paul Komminoth
Clonal analysis of sporadic pancreatic endocrine tumours.
The Journal of pathology 1998;186(4):363-71.
1998: Bruno Guhl; Martin Ziak; Jürgen Roth
Unconventional antigen retrieval for carbohydrate and protein antigens.
Histochemistry and cell biology 1998;110(6):603-11.
1998: Ernst J M Speel; Parvin Saremaslani; Jürgen Roth; Anton H N Hopman; Paul Komminoth
Improved mRNA in situ hybridization on formaldehyde-fixed and paraffin-embedded tissue using signal amplification with different haptenized tyramides.
Histochemistry and cell biology 1998;110(6):571-7.
1998: WK Seelentag; WP Li; S F Schmitz; U Metzger; P Aeberhard; Philipp U Heitz; Jürgen Roth
Prognostic value of beta1,6-branched oligosaccharides in human colorectal carcinoma.
Cancer research 1998;58(23):5559-64.
1998: Claude Jakob; Patricie Burda; Jürgen Roth; Markus Aebi
Degradation of misfolded endoplasmic reticulum glycoproteins in Saccharomyces cerevisiae is determined by a specific oligosaccharide structure.
The Journal of cell biology 1998;142(5):1223-33.
1998: Jürgen Roth; Douglas J Taatjes
Tubules of the trans Golgi apparatus visualized by immunoelectron microscopy.
Histochemistry and cell biology 1998;109(5-6):545-53.
1998: Claude Jakob; Patricie Burda; S te Heesen; Markus Aebi; Jürgen Roth
Genetic tailoring of N-linked oligosaccharides: the role of glucose residues in glycoprotein processing of Saccharomyces cerevisiae in vivo.
Glycobiology 1998;8(2):155-64.
1998: Christian Zuber; W P Li; Jürgen Roth
Blot analysis with lectins for the evaluation of glycoproteins in cultured cells and tissues.
Methods in molecular medicine 1998;9():159-66.
1998: Jürgen Roth; Christian Zuber; T Sata; W P Li
Lectin-Gold Histochemistry on Paraffin and Lowicryl K4M Sections Using Biotin and Digoxigenin-Conjugated Lectins.
Methods in molecular medicine 1998;9():41-53.
1997: T Flura; D Brada; Martin Ziak; Jürgen Roth
Expression of a cDNA encoding the glucose trimming enzyme glucosidase II in CHO cells and molecular characterization of the enzyme deficiency in a mutant mouse lymphoma cell line.
Glycobiology 1997;7(5):617-24.
1997: WP Li; Jürgen Roth
Expression of beta 1,6 branched asparagine-linked oligosaccharides in non-mitotic and non-migratory cells of normal human and rat tissues.
International journal of cancer. Journal international du cancer 1997;71(3):483-90.
1997: WK Seelentag; Roland Böni; U Günthert; E Futo; Guenter Burg; Philipp U Heitz; Jürgen Roth
Expression of CD44 isoforms and beta 1,6-branched oligosaccharides in human malignant melanoma is correlated with tumor progression but not with metastatic potential.
Journal of cutaneous pathology 1997;24(4):206-11.
1997: T Murayama; Christian Zuber; WK Seelentag; WP Li; Wolfgang Kemmner; Philipp U Heitz; Jürgen Roth
Colon carcinoma glycoproteins carrying alpha 2,6-linked sialic acid reactive with Sambucus nigra agglutinin are not constitutively expressed in normal human colon mucosa and are distinct from sialyl-Tn antigen.
International journal of cancer. Journal international du cancer 1997;70(5):575-81.
1996: Paul Komminoth; W K Seelentag; Parvin Saremaslani; Philipp U Heitz; Jürgen Roth
CD44 isoform expression in the diffuse neuroendocrine system. II. Benign and malignant tumors.
Histochemistry and cell biology 1996;106(6):551-62.
1996: W K Seelentag; Paul Komminoth; Parvin Saremaslani; Philipp U Heitz; Jürgen Roth
CD44 isoform expression in the diffuse neuroendocrine system. I. Normal cells and hyperplasia.
Histochemistry and cell biology 1996;106(6):543-50.
1996: W P Li; Paul Komminoth; Christian Zuber; G Klöppel; Philipp U Heitz; Jürgen Roth
Can malignancy in insulinoma be predicted by the expression patterns of beta 1,6 branching of asparagine-linked oligosaccharides and polysialic acid of the neural cell adhesion molecule?
Virchows Archiv : an international journal of pathology 1996;429(4-5):197-204.
1996: W K Seelentag; U Günthert; Parvin Saremaslani; E Futo; M Pfaltz; Philipp U Heitz; Jürgen Roth
CD44 standard and variant isoform expression in normal human skin appendages and epidermis.
Histochemistry and cell biology 1996;106(3):283-9.
1996: B Qu; Martin Ziak; Christian Zuber; Jürgen Roth
Poly (alpha 2,8-deaminoneuraminic acid) is expressed in lung on a single 150-kDa glycoprotein and is an oncodevelopmental antigen.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(17):8995-8.
1996: Jürgen Roth; Christian Zuber; Paul Komminoth; T Sata; W P Li; Philipp U Heitz
Applications of immunogold and lectin-gold labeling in tumor research and diagnosis.
Histochemistry and cell biology 1996;106(1):131-48.
1996: Jürgen Roth
Protein glycosylation in the endoplasmic reticulum and the Golgi apparatus and cell type-specificity of cell surface glycoconjugate expression: analysis by the protein A-gold and lectin-gold techniques.
Histochemistry and cell biology 1996;106(1):79-92.
1996: Jürgen Roth
The silver anniversary of gold: 25 years of the colloidal gold marker system for immunocytochemistry and histochemistry.
Histochemistry and cell biology 1996;106(1):1-8.
1996: W K Seelentag; U Günthert; Parvin Saremaslani; E Futo; M Pfaltz; Philipp U Heitz; Jürgen Roth
CD44 standard and variant isoform expression in human epidermal skin tumors is not correlated with tumor aggressiveness but down-regulated during proliferation and tumor de-differentiation.
International journal of cancer. Journal international du cancer 1996;69(3):218-24.
1996: Paul Komminoth; Jürgen Roth; S Muletta-Feurer; Parvin Saremaslani; W K Seelentag; Philipp U Heitz
RET proto-oncogene point mutations in sporadic neuroendocrine tumors.
The Journal of clinical endocrinology and metabolism 1996;81(6):2041-6.
1996: Martin Ziak; B Qu; X Zuo; Christian Zuber; A Kanamori; K Kitajima; S Inoue; Y Inoue; Jürgen Roth
Occurrence of poly(alpha2,8-deaminoneuraminic acid) in mammalian tissues: widespread and developmentally regulated but highly selective expression on glycoproteins.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2759-63.
1995: B C Padberg; S Schröder; W Jochum; Hartwig Kastendieck; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Absence of RET proto-oncogene point mutations in sporadic hyperplastic and neoplastic lesions of the parathyroid gland.
The American journal of pathology 1995;147(6):1600-7.
1995: E P Scheidegger; L R Sternberg; Jürgen Roth; John B Lowe
A human STX cDNA confers polysialic acid expression in mammalian cells.
The Journal of biological chemistry 1995;270(39):22685-8.
1995: Paul Komminoth; E K Kunz; Xavier Matias-Guiu; Olaf Hiort; G Christiansen; A Colomer; Jürgen Roth; Philipp U Heitz
Analysis of RET protooncogene point mutations distinguishes heritable from nonheritable medullary thyroid carcinomas.
Cancer 1995;76(3):479-89.
1995: Jürgen Roth; Paul Komminoth; Philipp U Heitz
Topographic abnormalities of proinsulin to insulin conversion in functioning human insulinomas. Comparison of immunoelectron microscopic and clinical data.
The American journal of pathology 1995;147(2):489-502.
1995: Paul Komminoth; Jürgen Roth; S Schröder; Parvin Saremaslani; Philipp U Heitz
Overlapping expression of immunohistochemical markers and synaptophysin mRNA in pheochromocytomas and adrenocortical carcinomas. Implications for the differential diagnosis of adrenal gland tumors.
Laboratory investigation; a journal of technical methods and pathology 1995;72(4):424-31.
1995: Jürgen Roth; Irwin J Goldstein
Subcellular distribution of terminal alpha-D- and beta-D-galactosyl residues in Ehrlich tumour cells studied by lectin-gold techniques.
Glycoconjugate journal 1995;12(2):142-9.
1995: W K Seelentag; Renata Flury; M Schmid; Paul Komminoth; Parvin Saremaslani; U Günthert; Philipp U Heitz; Jürgen Roth
[Expression of CD44 isoforms in normal human liver and also in regenerative and neoplastic liver changes].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1995;79():144-7.
1994: Jürgen Roth; W P Li; Randall N Knibbs; D K MacCallum; Z Song; Irwin J Goldstein
Differential expression of cell surface sialoglycoconjugates on wild-type and cultured Ehrlich tumor cells as revealed by quantitative lectin-gold ultrastructural cytochemistry.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11353-7.
1994: P Scheidegger; J Papay; Christian Zuber; P M Lackie; Jürgen Roth
Cellular site of synthesis and dynamics of cell surface re-expression of polysialic acid of the neural cell adhesion molecule.
European journal of biochemistry / FEBS 1994;225(3):1097-103.
1994: Paul Komminoth; Volker Adams; A A Long; Jürgen Roth; Parvin Saremaslani; Renata Flury; M Schmid; Philipp U Heitz
Evaluation of methods for hepatitis C virus detection in archival liver biopsies. Comparison of histology, immunohistochemistry, in-situ hybridization, reverse transcriptase polymerase chain reaction (RT-PCR) and in-situ RT-PCR.
Pathology, research and practice 1994;190(11):1017-25.
1994: Paul Komminoth; E Kunz; Olaf Hiort; S Schröder; Xavier Matias-Guiu; G Christiansen; Jürgen Roth; Philipp U Heitz
Detection of RET proto-oncogene point mutations in paraffin-embedded pheochromocytoma specimens by nonradioactive single-strand conformation polymorphism analysis and direct sequencing.
The American journal of pathology 1994;145(4):922-9.
1994: Jürgen Roth; Yu Wang; A E Eckhardt; RL Hill
Subcellular localization of the UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-mediated O-glycosylation reaction in the submaxillary gland.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):8935-9.
1994: P M Lackie; Christian Zuber; Jürgen Roth
Polysialic acid of the neural cell adhesion molecule (N-CAM) is widely expressed during organogenesis in mesodermal and endodermal derivatives.
Differentiation; research in biological diversity 1994;57(2):119-31.
1994: W P Li; Christian Zuber; Philipp U Heitz; Jürgen Roth
Cytochemical staining for beta 1,6 branching of asparagine-linked oligosaccharides in variants of metastatic human colon carcinoma cells.
The American journal of pathology 1994;145(2):470-80.
1994: Paul Komminoth; Jürgen Roth; Parvin Saremaslani; Xavier Matias-Guiu; H J Wolfe; Philipp U Heitz
Polysialic acid of the neural cell adhesion molecule in the human thyroid: a marker for medullary thyroid carcinoma and primary C-cell hyperplasia. An immunohistochemical study on 79 thyroid lesions.
The American journal of surgical pathology 1994;18(4):399-411.
1994: E P Scheidegger; P M Lackie; J Papay; Jürgen Roth
In vitro and in vivo growth of clonal sublines of human small cell lung carcinoma is modulated by polysialic acid of the neural cell adhesion molecule.
Laboratory investigation; a journal of technical methods and pathology 1994;70(1):95-106.
1994: Paul Komminoth; Volker Adams; A A Long; Jürgen Roth; Parvin Saremaslani; Renata Flury; M Schmid; Philipp U Heitz
[Comparison of histology, immunohistochemistry, RT-PCR, in situ hybridization, and in situ RT-PCR for demonstration of hepatitis C virus in paraffin-embedded liver biopsies].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():220-5.
1994: Jürgen Roth
[Tumors--disorders of cell adhesion].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():22-5.
1993: W P Li; Christian Zuber; Jürgen Roth
Use of Phaseolus vulgaris leukoagglutinating lectin in histochemical and blotting techniques: a comparison of digoxigenin- and biotin-labelled lectins.
Histochemistry 1993;100(5):347-56.
1993: Jürgen Roth
Cellular sialoglycoconjugates: a histochemical perspective.
The Histochemical journal 1993;25(10):687-710.
1993: M Takagaki; Randall N Knibbs; Jürgen Roth; Irwin J Goldstein
Monoclonal antibodies that recognize the trisaccharide epitope Gal alpha 1-3Gal beta 1-4GlcNAc present on Ehrlich tumor cell membrane glycoproteins.
Histochemistry 1993;100(2):139-47.
1992: Jürgen Roth; Parvin Saremaslani; Christian Zuber
Versatility of anti-horseradish peroxidase antibody-gold complexes for cytochemistry and in situ hybridization: preparation and application of soluble complexes with streptavidin-peroxidase conjugates and biotinylated antibodies.
Histochemistry 1992;98(4):229-36.
1992: Jürgen Roth; Parvin Saremaslani; M J Warhol; Philipp U Heitz
Improved accuracy in diagnostic immunohistochemistry, lectin histochemistry and in situ hybridization using a gold-labeled horseradish peroxidase antibody and silver intensification.
Laboratory investigation; a journal of technical methods and pathology 1992;67(2):263-9.
1992: Christian Zuber; P M Lackie; W A Catterall; Jürgen Roth
Polysialic acid is associated with sodium channels and the neural cell adhesion molecule N-CAM in adult rat brain.
The Journal of biological chemistry 1992;267(14):9965-71.
1992: Jürgen Roth; A Kempf; G Reuter; R Schauer; Walter J Gehring
Occurrence of sialic acids in Drosophila melanogaster.
Science (New York, N.Y.) 1992;256(5057):673-5.
1992: Jürgen Roth; G Klöppel; O D Madsen; M J Storch; Philipp U Heitz
Distribution patterns of proinsulin and insulin in human insulinomas: an immunohistochemical analysis in 76 tumors.
Virchows Archiv. B, Cell pathology including molecular pathology 1992;63(1):51-61.
1991: Christian Zuber; Jürgen Roth; T Misteli; A Nakano; Kelley W Moremen
DS28-6, a temperature-sensitive mutant of Chinese hamster ovary cells, expresses key phenotypic changes associated with brefeldin A treatment.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(21):9818-22.
1991: Paul Komminoth; Jürgen Roth; P M Lackie; D Bitter-Suermann; Philipp U Heitz
Polysialic acid of the neural cell adhesion molecule distinguishes small cell lung carcinoma from carcinoids.
The American journal of pathology 1991;139(2):297-304.
1991: P M Lackie; Christian Zuber; Jürgen Roth
Expression of polysialylated N-CAM during rat heart development.
Differentiation; research in biological diversity 1991;47(2):85-98.
1991: Jürgen Roth
Localization of glycosylation sites in the Golgi apparatus using immunolabeling and cytochemistry.
Journal of electron microscopy technique 1991;17(2):121-31.
1990: P M Lackie; Christian Zuber; Jürgen Roth
Polysialic acid and N-CAM localisation in embryonic rat kidney: mesenchymal and epithelial elements show different patterns of expression.
Development (Cambridge, England) 1990;110(3):933-47.
1990: Jürgen Roth; D Brada; P M Lackie; J Schweden; Ernst Bause
Oligosaccharide trimming Man9-mannosidase is a resident ER protein and exhibits a more restricted and local distribution than glucosidase II.
European journal of cell biology 1990;53(1):131-41.
1990: T Sata; Christian Zuber; S J Rinderle; Irwin J Goldstein; Jürgen Roth
Expression patterns of the T antigen and the cryptic T antigen in rat fetuses: detection with the lectin amaranthin.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1990;38(6):763-74.
1990: Christian Zuber; Jürgen Roth
The relationship of polysialic acid and the neural cell adhesion molecule N-CAM in Wilms tumor and their subcellular distributions.
European journal of cell biology 1990;51(2):313-21.
1990: D Brada; D Kerjaschki; Jürgen Roth
Cell type-specific post-Golgi apparatus localization of a "resident" endoplasmic reticulum glycoprotein, glucosidase II.
The Journal of cell biology 1990;110(2):309-18.
1990: Jürgen Roth; Christian Zuber
Immunoelectron microscopic investigation of surface coat of Wilms tumor cells. Dense lamina is composed of highly sialylated neural cell adhesion molecule.
Laboratory investigation; a journal of technical methods and pathology 1990;62(1):55-60.
1990: Philipp U Heitz; Paul Komminoth; P M Lackie; Christian Zuber; Jürgen Roth
[Demonstration of polysialic acid and N-CAM in neuroendocrine tumors].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1990;74():376-7.
1990: Jürgen Roth; T Sata; P Komminoth; B Stamm; M J Warhol; Irwin J Goldstein; Philipp U Heitz
[Properties of the cell surface of normal and malignant cells: investigations on polysialic acid and terminal sialic acid residues in specific linkages].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1990;74():186-95.
1990: Jürgen Roth; D J Taatjes; K T Tokuyasu
Contrasting of Lowicryl K4M thin sections.
Histochemistry 1990;95(2):123-36.
1990: T Sata; Christian Zuber; Jürgen Roth
Lectin--digoxigenin conjugates: a new hapten system for glycoconjugate cytochemistry.
Histochemistry 1990;94(1):1-11.
1989: T Sata; P M Lackie; D J Taatjes; W Peumans; Jürgen Roth
Detection of the Neu5 Ac (alpha 2,3) Gal (beta 1,4) GlcNAc sequence with the leukoagglutinin from Maackia amurensis: light and electron microscopic demonstration of differential tissue expression of terminal sialic acid in alpha 2,3- and alpha 2,6-linkage.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1989;37(11):1577-88.
1989: Jürgen Roth; Philipp U Heitz
Immunolabeling with the protein A-gold technique: an overview.
Ultrastructural pathology 1989;13(5-6):467-84.
1989: E U Lee; Jürgen Roth; J C Paulson
Alteration of terminal glycosylation sequences on N-linked oligosaccharides of Chinese hamster ovary cells by expression of beta-galactoside alpha 2,6-sialyltransferase.
The Journal of biological chemistry 1989;264(23):13848-55.
1989: G Egea; Irwin J Goldstein; Jürgen Roth
Light and electron microscopic detection of (3 Gal beta 1,4 GlcNAc beta 1) sequences in asparagine-linked oligosaccharides with the Datura stramonium lectin.
Histochemistry 1989;92(6):515-22.
1989: Jürgen Roth
Postembedding labeling on Lowicryl K4M tissue sections: detection and modification of cellular components.
Methods in cell biology 1989;31():513-51.
1989: Jürgen Roth; M Kasper; B Stamm; W H Häcki; M J Storch; O D Madsen; G Klöppel; Philipp U Heitz
Localization of proinsulin and insulin in human insulinoma: preliminary immunohistochemical results.
Virchows Archiv. B, Cell pathology including molecular pathology 1989;56(5):287-92.
1989: Jürgen Roth; D J Taatjes; M J Warhol
Prevention of non-specific interactions of gold-labeled reagents on tissue sections.
Histochemistry 1989;92(1):47-56.
1988: P Wagner; Jürgen Roth
Occurrence and distribution of sialic acid residues in developing rat glomerulus: investigations with the Limax flavus and the wheat germ agglutinin.
European journal of cell biology 1988;47(2):259-69.
1988: Jürgen Roth; I Blaha; D Bitter-Suermann; Philipp U Heitz
Blastemal cells of nephroblastomatosis complex share an onco-developmental antigen with embryonic kidney and Wilms' tumor. An immunohistochemical study on polysialic acid distribution.
The American journal of pathology 1988;133(3):596-608.
1988: D J Taatjes; Jürgen Roth; W Peumans; Irwin J Goldstein
Elderberry bark lectin--gold techniques for the detection of Neu5Ac (alpha 2,6) Gal/GalNAc sequences: applications and limitations.
The Histochemical journal 1988;20(9):478-90.
1988: D J Taatjes; Jürgen Roth
Alteration in sialyltransferase and sialic acid expression accompanies cell differentiation in rat intestine.
European journal of cell biology 1988;46(2):289-98.
1988: D J Taatjes; Jürgen Roth; J Weinstein; J C Paulson
Post-Golgi apparatus localization and regional expression of rat intestinal sialyltransferase detected by immunoelectron microscopy with polypeptide epitope-purified antibody.
The Journal of biological chemistry 1988;263(13):6302-9.
1988: Jürgen Roth; P Greenwell; W M Watkins
Immunolocalization of blood group A gene specified alpha 1,3N-acetylgalactosaminyltransferase and blood group A substance in the trans-tubular network of the Golgi apparatus and mucus of intestinal goblet cells.
European journal of cell biology 1988;46(1):105-12.
1988: M Deschuyteneer; A E Eckhardt; Jürgen Roth; RL Hill
The subcellular localization of apomucin and nonreducing terminal N-acetylgalactosamine in porcine submaxillary glands.
The Journal of biological chemistry 1988;263(5):2452-9.
1988: Jürgen Roth; J M Lucocq; D J Taatjes
Light and electron microscopical detection of sugar residues in tissue sections by gold labeled lectins and glycoproteins. I. Methodological aspects.
Acta histochemica. Supplementband 1988;36():81-99.
1988: Jürgen Roth; D J Taatjes; J M Lucocq; P M Charest
Light and electron microscopical detection of sugar residues in tissue sections by gold labeled lectins and glycoproteins. II. Applications in the study of the topology of Golgi apparatus glycosylation steps and the regional distribution of lectin binding sites in the plasma membrane.
Acta histochemica. Supplementband 1988;36():125-40.
1988: Jürgen Roth; D Brada; I Blaha; C Ghielmini; D Bitter-Suermann; P Komminoth; Philipp U Heitz
Evaluation of polysialic acid in the diagnosis of Wilms' tumor. A comparative study on urinary tract tumors and non-neuroendocrine tumors.
Virchows Archiv. B, Cell pathology including molecular pathology 1988;56(2):95-102.
1987: D J Taatjes; T H Chen; B Ackerström; L Björck; E Carlemalm; Jürgen Roth
Streptococcal protein G-gold complex: comparison with staphylococcal protein A-gold complex for spot blotting and immunolabeling.
European journal of cell biology 1987;45(1):151-9.
1987: Jürgen Roth
Subcellular organization of glycosylation in mammalian cells.
Biochimica et biophysica acta 1987;906(3):405-36.
1987: D J Taatjes; Jürgen Roth; J Weinstein; J C Paulson; N L Shaper; Joel H Shaper
Codistribution of galactosyl- and sialyltransferase: reorganization of trans Golgi apparatus elements in hepatocytes in intact liver and cell culture.
European journal of cell biology 1987;44(2):187-94.
1987: Jürgen Roth; P Greenwell; W M Watkins
Subcellular distribution of the products of the blood group A gene.
Biochemical Society transactions 1987;15(4):599-601.
1986: J M Lucocq; P M Charest; Jürgen Roth
Light and electron microscopic localization of sialic acid residues with the Limax flavus lectin-fetuin-gold procedure.
Acta histochemica. Supplementband 1986;32():227.
1984: Jürgen Roth; J M Lucocq; P M Charest
Light and electron microscopic demonstration of sialic acid residues with the lectin from Limax flavus: a cytochemical affinity technique with the use of fetuin-gold complexes.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1984;32(11):1167-76.