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Robert Roth

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
82
Elsworth, John
50
Redmond, Eugene
43
Deutch, Ariel
39
Taylor, Jane
31
Sladek, John
28
Morrow, Bret
19
Jentsch, David
16
Bradberry, Charles
16
Bannon, Michael
13
Leranth, Csaba
10
During, Matthew
10
Verrico, Christopher
9
Kuhar, Michael
9
Naftolin, Frederick
9
Collier, Timothy

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Publications

TOP 3
Andrews Zane B; Erion Derek; Beiler Rudolph; Liu Zhong-Wu; Abizaid Alfonso; Zigman Jeffrey; Elsworth John D; Savitt Joseph M; DiMarchi Richard; Tschoep Matthias; Roth Robert H; Gao Xiao-Bing; Horvath Tamas L
Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism.
Redmond D E; Elsworth J D; Roth R H; Leranth C; Collier T J; Blanchard B; Bjugstad K B; Samulski R J; Aebischer P; Sladek J R
Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF.
Jentsch J David; Sanchez Diana; Elsworth John D; Roth Robert H
Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype.

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All Publications

2009: Andrews Zane B; Erion Derek; Beiler Rudolph; Liu Zhong-Wu; Abizaid Alfonso; Zigman Jeffrey; Elsworth John D; Savitt Joseph M; DiMarchi Richard; Tschoep Matthias; Roth Robert H; Gao Xiao-Bing; Horvath Tamas L
Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(45):14057-65.
2009: Redmond D E; Elsworth J D; Roth R H; Leranth C; Collier T J; Blanchard B; Bjugstad K B; Samulski R J; Aebischer P; Sladek J R
Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF.
The Journal of comparative neurology 2009;515(1):31-40.
2008: Jentsch J David; Sanchez Diana; Elsworth John D; Roth Robert H
Clonidine and guanfacine attenuate phencyclidine-induced dopamine overflow in rat prefrontal cortex: mediating influence of the alpha-2A adrenoceptor subtype.
Brain research 2008;1246():41-6.
2008: Bjugstad Kimberly B; Teng Yang D; Redmond D Eugene; Elsworth John D; Roth Robert H; Cornelius Shannon K; Snyder Evan Y; Sladek John R
Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease.
Experimental neurology 2008;211(2):362-9.
2008: Elsworth J D; Redmond D E; Leranth C; Bjugstad K B; Sladek J R; Collier T J; Foti S B; Samulski R J; Vives K P; Roth R H
AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons.
Experimental neurology 2008;211(1):252-8.
2008: Elsworth John D; Jentsch J David; Morrow Bret A; Redmond D Eugene; Roth Robert H
Clozapine normalizes prefrontal cortex dopamine transmission in monkeys subchronically exposed to phencyclidine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(3):491-6.
2008: Sladek J R; Bjugstad K B; Collier T J; Bundock E A; Blanchard B C; Elsworth J D; Roth R H; Redmond D E
Embryonic substantia nigra grafts show directional outgrowth to cografted striatal grafts and potential for pathway reconstruction in nonhuman primate.
Cell transplantation 2008;17(4):427-44.
2007: Morrow Bret A; Hajszan Tibor; Leranth Csaba; Elsworth John D; Roth Robert H
Prenatal exposure to cocaine is associated with increased number of spine synapses in rat prelimbic cortex.
Synapse (New York, N.Y.) 2007;61(10):862-5.
2007: Redmond D Eugene; Bjugstad Kimberly B; Teng Yang D; Ourednik Vaclav; Ourednik Jitka; Wakeman Dustin R; Parsons Xuejun H; Gonzalez Rodolfo; Blanchard Barbara C; Kim Seung U; Gu Zezong; Lipton Stuart A; Markakis Eleni A; Roth Robert H; Elsworth John D; Sladek John R; Sidman Richard L; Snyder Evan Y
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):12175-80.
2007: Elsworth J D; Morrow B A; Nguyen V-T; Mitra J; Picciotto M R; Roth R H
Prenatal cocaine exposure enhances responsivity of locus coeruleus norepinephrine neurons: role of autoreceptors.
Neuroscience 2007;147(2):419-27.
2007: Morrow Bret A; Elsworth John D; Roth Robert H
Repeated phencyclidine in monkeys results in loss of parvalbumin-containing axo-axonic projections in the prefrontal cortex.
Psychopharmacology 2007;192(2):283-90.
2007: Morrow Bret A; Roth Robert H; Redmond D Eugene; Sladek John R; Elsworth John D
Apoptotic natural cell death in developing primate dopamine midbrain neurons occurs during a restricted period in the second trimester of gestation.
Experimental neurology 2007;204(2):802-7.
2006: Abizaid Alfonso; Liu Zhong-Wu; Andrews Zane B; Shanabrough Marya; Borok Erzsebet; Elsworth John D; Roth Robert H; Sleeman Mark W; Picciotto Marina R; Tschöp Matthias H; Gao Xiao-Bing; Horvath Tamas L
Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite.
The Journal of clinical investigation 2006;116(12):3229-39.
2006: Hajszan Tibor; Leranth Csaba; Roth Robert H
Subchronic phencyclidine treatment decreases the number of dendritic spine synapses in the rat prefrontal cortex.
Biological psychiatry 2006;60(6):639-44.
2006: Andrews Zane B; Rivera Alicia; Elsworth John D; Roth Robert H; Agnati Luigi; Gago Belen; Abizaid Alfonso; Schwartz Michael; Fuxe Kjell; Horvath Tamas L
Uncoupling protein-2 promotes nigrostriatal dopamine neuronal function.
The European journal of neuroscience 2006;24(1):32-6.
2005: Morrow Bret A; Redmond D Eugene; Roth Robert H; Elsworth John D
Development of A9/A10 dopamine neurons during the second and third trimesters in the African green monkey.
The Journal of comparative neurology 2005;488(2):215-23.
2005: Morrow Bret A; Elsworth John D; Roth Robert H
Prenatal exposure to cocaine selectively disrupts the development of parvalbumin containing local circuit neurons in the medial prefrontal cortex of the rat.
Synapse (New York, N.Y.) 2005;56(1):1-11.
2005: Andrews Zane B; Horvath Balazs; Barnstable Colin J; Elsworth John; Yang Lichuan; Beal M Flynt; Roth Robert H; Matthews Russell T; Horvath Tamas L
Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(1):184-91.
2005: Bjugstad Kimberly B; Redmond D Eugene; Teng Yang D; Elsworth J D; Roth R H; Blanchard B C; Snyder Evan Y; Sladek John R
Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures.
Cell transplantation 2005;14(4):183-92.
2004: Morrow Bret A; George Tony P; Roth Robert H
Noradrenergic alpha-2 agonists have anxiolytic-like actions on stress-related behavior and mesoprefrontal dopamine biochemistry.
Brain research 2004;1027(1-2):173-8.
2004: Verrico Christopher D; Jentsch J David; Roth Robert H; Taylor Jane R
Repeated, intermittent delta(9)-tetrahydrocannabinol administration to rats impairs acquisition and performance of a test of visuospatial divided attention.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(3):522-9.
2003: Redmond D Eugene; Zhao Ji-Liang; Randall Jeffry D; Eklund Aron C; Eusebi Leonard O V; Roth Robert H; Gullans Steven R; Jensen Roderick V
Spatiotemporal patterns of gene expression during fetal monkey brain development.
Brain research. Developmental brain research 2003;146(1-2):99-106.
2003: Horvath Tamas L; Diano Sabrina; Leranth Csaba; Garcia-Segura Luis Miguel; Cowley Michael A; Shanabrough Marya; Elsworth John D; Sotonyi Peter; Roth Robert H; Dietrich Edwin H; Matthews Russel T; Barnstable Colin J; Redmond D Eugene
Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease.
Endocrinology 2003;144(7):2757-60.
2003: Verrico Christopher D; Jentsch J David; Roth Robert H
Persistent and anatomically selective reduction in prefrontal cortical dopamine metabolism after repeated, intermittent cannabinoid administration to rats.
Synapse (New York, N.Y.) 2003;49(1):61-6.
2003: Morrow Bret A; Elsworth John D; Roth Robert H
Axo-axonic structures in the medial prefrontal cortex of the rat: reduction by prenatal exposure to cocaine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(12):5227-34.
2003: Verrico Christopher D; Jentsch J David; Dazzi Laura; Roth Robert H
Systemic, but not local, administration of cannabinoid CB1 receptor agonists modulate prefrontal cortical acetylcholine efflux in the rat.
Synapse (New York, N.Y.) 2003;48(4):178-83.
2002: De La Garza Richard; Jentsch J David; Verrico Christopher D; Roth Robert H
Adaptation of monoaminergic responses to phencyclidine in nucleus accumbens and prefrontal cortex following repeated treatment with fluoxetine or imipramine.
Brain research 2002;958(1):20-7.
2002: Morrow Bret A; Elsworth John D; Roth Robert H
Fear-like biochemical and behavioral responses in rats to the predator odor, TMT, are dependent on the exposure environment.
Synapse (New York, N.Y.) 2002;46(1):11-8.
2002: Redmond Andy J; Morrow Bret A; Elsworth John D; Roth Robert H
Selective activation of the A10, but not A9, dopamine neurons in the rat by the predator odor, 2,5-dihydro-2,4,5-trimethylthiazoline.
Neuroscience letters 2002;328(3):209-12.
2002: Morrow Bret A; Elsworth John D; Roth Robert H
Male rats exposed to cocaine in utero demonstrate elevated expression of Fos in the prefrontal cortex in response to environment.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;26(3):275-85.
2002: Morrow Bret A; Elsworth John D; Roth Robert H
Prenatal cocaine exposure disrupts non-spatial, short-term memory in adolescent and adult male rats.
Behavioural brain research 2002;129(1-2):217-23.
2002: Collier Timothy J; Sortwell Caryl E; Elsworth John D; Taylor Jane R; Roth Robert H; Sladek John R; Redmond D Eugene
Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP-treated monkeys: feasibility relevant to multiple-target grafting as a therapy for Parkinson's disease.
The Journal of comparative neurology 2002;442(4):320-30.
2001: Elsworth J D; Morrow B A; Roth R H
Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress.
Synapse (New York, N.Y.) 2001;42(2):80-3.
2001: Morrow B A; Elsworth J D; Roth R H
Prenatal exposure to cocaine reduces the number and enhances reactivity of A10 dopaminergic neurons to environmental stress.
Synapse (New York, N.Y.) 2001;41(4):337-44.
2001: Zachariou V; Caldarone B J; Weathers-Lowin A; George T P; Elsworth J D; Roth R H; Changeux J P; Picciotto M R
Nicotine receptor inactivation decreases sensitivity to cocaine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;24(5):576-89.
2001: George T P; Picciotto M R; Verrico C D; Roth R H
Effects of nicotine pretreatment on dopaminergic and behavioral responses to conditioned fear stress in rats: dissociation of biochemical and behavioral effects.
Biological psychiatry 2001;49(3):300-6.
2000: Leranth C; Roth R H; Elsworth J D; Naftolin F; Horvath T L; Redmond D E
Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: implications for Parkinson's disease and memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(23):8604-9.
2000: George T P; Verrico C D; Picciotto M R; Roth R H
Nicotinic modulation of mesoprefrontal dopamine neurons: pharmacologic and neuroanatomic characterization.
The Journal of pharmacology and experimental therapeutics 2000;295(1):58-66.
2000: Jentsch J D; Roth R H; Taylor J R
Object retrieval/detour deficits in monkeys produced by prior subchronic phencyclidine administration: evidence for cognitive impulsivity.
Biological psychiatry 2000;48(5):415-24.
2000: Morrow B A; Roth R H; Elsworth J D
TMT, a predator odor, elevates mesoprefrontal dopamine metabolic activity and disrupts short-term working memory in the rat.
Brain research bulletin 2000;52(6):519-23.
2000: George T P; Verrico C D; Xu L; Roth R H
Effects of repeated nicotine administration and footshock stress on rat mesoprefrontal dopamine systems: Evidence for opioid mechanisms.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;23(1):79-88.
2000: Morrow B A; Redmond A J; Roth R H; Elsworth J D
The predator odor, TMT, displays a unique, stress-like pattern of dopaminergic and endocrinological activation in the rat.
Brain research 2000;864(1):146-51.
2000: Morrow B A; Elsworth J D; Lee E J; Roth R H
Divergent effects of putative anxiolytics on stress-induced fos expression in the mesoprefrontal system of the rat.
Synapse (New York, N.Y.) 2000;36(2):143-54.
2000: Jentsch J D; Roth R H; Taylor J R
Role for dopamine in the behavioral functions of the prefrontal corticostriatal system: implications for mental disorders and psychotropic drug action.
Progress in brain research 2000;126():433-53.
2000: Elsworth J D; Taylor J R; Sladek J R; Collier T J; Redmond D E; Roth R H
Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment.
Neuroscience 2000;95(2):399-408.
1999: Morrow B A; Rosenberg S J; Roth R H
Chronic clozapine, but not haloperidol, alters the response of mesoprefrontal dopamine neurons to stress and clozapine challenges in rats.
Synapse (New York, N.Y.) 1999;34(1):28-35.
1999: Taylor J R; Elsworth J D; Lawrence M S; Sladek J R; Roth R H; Redmond D E
Spontaneous blink rates correlate with dopamine levels in the caudate nucleus of MPTP-treated monkeys.
Experimental neurology 1999;158(1):214-20.
1999: Morrow B A; Elsworth J D; Inglis F M; Roth R H
An antisense oligonucleotide reverses the footshock-induced expression of fos in the rat medial prefrontal cortex and the subsequent expression of conditioned fear-induced immobility.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(13):5666-73.
1999: Berridge C W; Mitton E; Clark W; Roth R H
Engagement in a non-escape (displacement) behavior elicits a selective and lateralized suppression of frontal cortical dopaminergic utilization in stress.
Synapse (New York, N.Y.) 1999;32(3):187-97.
1999: Youngren K D; Inglis F M; Pivirotto P J; Jedema H P; Bradberry C W; Goldman-Rakic P S; Roth R H; Moghaddam B
Clozapine preferentially increases dopamine release in the rhesus monkey prefrontal cortex compared with the caudate nucleus.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(5):403-12.
1999: Morrow B A; Elsworth J D; Zito C; Roth R H
Biochemical and behavioral anxiolytic-like effects of R(+)HA-966 at the level of the ventral tegmental area in rats.
Psychopharmacology 1999;143(3):227-34.
1999: Jentsch J D; Taylor J R; Elsworth J D; Redmond D E; Roth R H
Altered frontal cortical dopaminergic transmission in monkeys after subchronic phencyclidine exposure: involvement in frontostriatal cognitive deficits.
Neuroscience 1999;90(3):823-32.
1999: Jentsch J D; Roth R H
The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(3):201-25.
1999: Jentsch J D; Taylor J R; Redmond D E; Elsworth J D; Youngren K D; Roth R H
Dopamine D4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys.
Psychopharmacology 1999;142(1):78-84.
1999: Abi-Saab W M; Bubser M; Roth R H; Deutch A Y
5-HT2 receptor regulation of extracellular GABA levels in the prefrontal cortex.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1999;20(1):92-6.
1999: Morrow B A; Elsworth J D; Rasmusson A M; Roth R H
The role of mesoprefrontal dopamine neurons in the acquisition and expression of conditioned fear in the rat.
Neuroscience 1999;92(2):553-64.
1998: Jentsch J D; Dazzi L; Chhatwal J P; Verrico C D; Roth R H
Reduced prefrontal cortical dopamine, but not acetylcholine, release in vivo after repeated, intermittent phencyclidine administration to rats.
Neuroscience letters 1998;258(3):175-8.
1998: Leranth C; Sladek J R; Roth R H; Redmond D E
Efferent synaptic connections of dopaminergic neurons grafted into the caudate nucleus of experimentally induced parkinsonian monkeys are different from those of control animals.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1998;123(3):323-33.
1998: George T P; Verrico C D; Roth R H
Effects of repeated nicotine pre-treatment on mesoprefrontal dopaminergic and behavioral responses to acute footshock stress.
Brain research 1998;801(1-2):36-49.
1998: Jentsch J D; Taylor J R; Roth R H
Subchronic phencyclidine administration increases mesolimbic dopaminergic system responsivity and augments stress- and psychostimulant-induced hyperlocomotion.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1998;19(2):105-13.
1998: Jentsch J D; Tran A; Taylor J R; Roth R H
Prefrontal cortical involvement in phencyclidine-induced activation of the mesolimbic dopamine system: behavioral and neurochemical evidence.
Psychopharmacology 1998;138(1):89-95.
1998: During M J; Samulski R J; Elsworth J D; Kaplitt M G; Leone P; Xiao X; Li J; Freese A; Taylor J R; Roth R H; Sladek J R; O'Malley K L; Redmond D E
In vivo expression of therapeutic human genes for dopamine production in the caudates of MPTP-treated monkeys using an AAV vector.
Gene therapy 1998;5(6):820-7.
1998: Elsworth J D; Brittan M S; Taylor J R; Sladek J R; Redmond D E; Innis R B; Zea-Ponce Y; Roth R H
Upregulation of striatal D2 receptors in the MPTP-treated vervet monkey is reversed by grafts of fetal ventral mesencephalon: an autoradiographic study.
Brain research 1998;795(1-2):55-62.
1998: Jentsch J D; Verrico C D; Le D; Roth R H
Repeated exposure to delta 9-tetrahydrocannabinol reduces prefrontal cortical dopamine metabolism in the rat.
Neuroscience letters 1998;246(3):169-72.
1998: Sortwell C E; Blanchard B C; Collier T J; Elsworth J D; Taylor J R; Roth R H; Redmond D E; Sladek J R
Pattern of synaptophysin immunoreactivity within mesencephalic grafts following transplantation in a parkinsonian primate model.
Brain research 1998;791(1-2):117-24.
1998: Sladek J R; Collier T J; Elsworth J D; Roth R H; Taylor J R; Redmond D E
Intrastriatal grafts from multiple donors do not result in a proportional increase in survival of dopamine neurons in nonhuman primates.
Cell transplantation 1998;7(2):87-96.
1998: Jentsch J D; Wise A; Katz Z; Roth R H
Alpha-noradrenergic receptor modulation of the phencyclidine- and delta9-tetrahydrocannabinol-induced increases in dopamine utilization in rat prefrontal cortex.
Synapse (New York, N.Y.) 1998;28(1):21-6.
1998: Jentsch J D; Elsworth J D; Taylor J R; Redmond D E; Roth R H
Dysregulation of mesoprefrontal dopamine neurons induced by acute and repeated phencyclidine administration in the nonhuman primate: implications for schizophrenia.
Advances in pharmacology (San Diego, Calif.) 1998;42():810-4.
1997: Taylor J R; Elsworth J D; Roth R H; Sladek J R; Redmond D E
Severe long-term 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the vervet monkey (Cercopithecus aethiops sabaeus).
Neuroscience 1997;81(3):745-55.
1997: Morrow B A; Lee E J; Taylor J R; Elsworth J D; Nye H E; Roth R H
(S)-(-)-HA-966, a gamma-hydroxybutyrate-like agent, prevents enhanced mesocorticolimbic dopamine metabolism and behavioral correlates of restraint stress, conditioned fear and cocaine sensitization.
The Journal of pharmacology and experimental therapeutics 1997;283(2):712-21.
1997: Jentsch J D; Tran A; Le D; Youngren K D; Roth R H
Subchronic phencyclidine administration reduces mesoprefrontal dopamine utilization and impairs prefrontal cortical-dependent cognition in the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;17(2):92-9.
1997: Jentsch J D; Redmond D E; Elsworth J D; Taylor J R; Youngren K D; Roth R H
Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine.
Science (New York, N.Y.) 1997;277(5328):953-5.
1997: Murphy B L; Roth R H; Arnsten A F
Clozapine reverses the spatial working memory deficits induced by FG7142 in monkeys.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;16(6):433-7.
1997: Jentsch J D; Andrusiak E; Tran A; Bowers M B; Roth R H
Delta 9-tetrahydrocannabinol increases prefrontal cortical catecholaminergic utilization and impairs spatial working memory in the rat: blockade of dopaminergic effects with HA966.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;16(6):426-32.
1997: Alexander T; Sortwell C E; Sladek C D; Roth R H; Steece-Collier K
Comparison of neurotoxicity following repeated administration of l-dopa, d-dopa and dopamine to embryonic mesencephalic dopamine neurons in cultures derived from Fisher 344 and Sprague-Dawley donors.
Cell transplantation 1997;6(3):309-15.
1997: Collier T J; Redmond D E; Roth R H; Elsworth J D; Taylor J R; Sladek J R
Metabolic energy capacity of dopaminergic grafts and the implanted striatum in parkinsonian nonhuman primates as visualized with cytochrome oxidase histochemistry.
Cell transplantation 1997;6(2):135-40.
1997: Elsworth J D; Roth R H
Dopamine synthesis, uptake, metabolism, and receptors: relevance to gene therapy of Parkinson's disease.
Experimental neurology 1997;144(1):4-9.
1997: Jentsch J D; Elsworth J D; Redmond D E; Roth R H
Phencyclidine increases forebrain monoamine metabolism in rats and monkeys: modulation by the isomers of HA966.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(5):1769-75.
1997: Tam S Y; Roth R H
Mesoprefrontal dopaminergic neurons: can tyrosine availability influence their functions?
Biochemical pharmacology 1997;53(4):441-53.
1997: Tam S Y; Elsworth J D; Sladek J R; Redmond D E; Roth R H
Identification of novel variants of trkC mRNA transcripts in brain of African green monkeys.
Experimental neurology 1997;143(1):172-6.
1996: Murphy B L; Arnsten A F; Jentsch J D; Roth R H
Dopamine and spatial working memory in rats and monkeys: pharmacological reversal of stress-induced impairment.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(23):7768-75.
1996: Horger B A; Taylor J R; Elsworth J D; Jatlow P I; Roth R H
Sensitization to the locomotor activating effects of cocaine following cocaethylene-preexposure.
Brain research 1996;733(1):133-7.
1996: Roth R H; Williams R E
Comment on condylar movement and mandibular rotation during jaw opening.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 1996;110(3):21A-23A.
1996: Jatlow P; McCance E F; Bradberry C W; Elsworth J D; Taylor J R; Roth R H
Alcohol plus cocaine: the whole is more than the sum of its parts.
Therapeutic drug monitoring 1996;18(4):460-4.
1996: Goldstein L E; Rasmusson A M; Bunney B S; Roth R H
Role of the amygdala in the coordination of behavioral, neuroendocrine, and prefrontal cortical monoamine responses to psychological stress in the rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(15):4787-98.
1996: Deutch A Y; Lewis D A; Whitehead R E; Elsworth J D; Iadarola M J; Redmond D E; Roth R H
Effects of D2 dopamine receptor antagonists on Fos protein expression in the striatal complex and entorhinal cortex of the nonhuman primate.
Synapse (New York, N.Y.) 1996;23(3):182-91.
1996: Morrow B A; Roth R H
Serotonergic lesions alter cocaine-induced locomotor behavior and stress-activation of the mesocorticolimbic dopamine system.
Synapse (New York, N.Y.) 1996;23(3):174-81.
1996: Horger B A; Elsworth J D; Roth R H
Blockade of FG 7142-induced increased dopamine utilization by the glycine/NMDA receptor antagonist (+)-HA 966.
Journal of neurochemistry 1996;66(5):1959-62.
1996: Elsworth J D; Sladek J R; Taylor J R; Collier T J; Redmond D E; Roth R H
Early gestational mesencephalon grafts, but not later gestational mesencephalon, cerebellum or sham grafts, increase dopamine in caudate nucleus of MPTP-treated monkeys.
Neuroscience 1996;72(2):477-84.
1996: Elsworth J D; Brittan M S; Taylor J R; Sladek J R; al-Tikriti M S; Zea-Ponce Y; Innis R B; Redmond D E; Roth R H
Restoration of dopamine transporter density in the striatum of fetal ventral mesencephalon-grafted, but not sham-grafted, MPTP-treated parkinsonian monkeys.
Cell transplantation 1996;5(2):315-25.
1996: Morrow B A; Elsworth J D; Roth R H
Tyrosine enhances behavioral and mesocorticolimbic dopaminergic responses to aversive conditioning.
Synapse (New York, N.Y.) 1996;22(2):100-5.
1996: Murphy B L; Arnsten A F; Goldman-Rakic P S; Roth R H
Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(3):1325-9.
1996: Horger B A; Roth R H
The role of mesoprefrontal dopamine neurons in stress.
Critical reviews in neurobiology 1996;10(3-4):395-418.
1995: Morrow B A; Taylor J R; Roth R H
Prior exposure to cocaine diminishes behavioral and biochemical responses to aversive conditioning: reversal by glycine/N-methyl-D-aspartate antagonist co-treatment.
Neuroscience 1995;69(1):233-40.
1995: Price L H; Spencer D D; Marek K L; Robbins R J; Leranth C; Farhi A; Naftolin F; Roth R H; Bunney B S; Hoffer P B
Psychiatric status after human fetal mesencephalic tissue transplantation in Parkinson's disease.
Biological psychiatry 1995;38(8):498-505.
1995: Horger B A; Elsworth J D; Roth R H
Selective increase in dopamine utilization in the shell subdivision of the nucleus accumbens by the benzodiazepine inverse agonist FG 7142.
Journal of neurochemistry 1995;65(2):770-4.
1995: Sass K J; Buchanan C P; Westerveld M; Marek K L; Farhi A; Robbins R J; Naftolin F; Vollmer T L; Leranth C; Roth R H
General cognitive ability following unilateral and bilateral fetal ventral mesencephalic tissue transplantation for treatment of Parkinson's disease.
Archives of neurology 1995;52(7):680-6.
1995: Rosin D L; Melia K; Knorr A M; Nestler E J; Roth R H; Duman R S
Chronic imipramine administration alters the activity and phosphorylation state of tyrosine hydroxylase in dopaminergic regions of rat brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1995;12(2):113-21.
1995: Roth R H
Occlusion and condylar position.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 1995;107(3):315-8.
1995: Abarca J; Gysling K; Roth R H; Bustos G
Changes in extracellular levels of glutamate and aspartate in rat substantia nigra induced by dopamine receptor ligands: in vivo microdialysis studies.
Neurochemical research 1995;20(2):159-69.
1995: Morrow B A; Taylor J R; Roth R H
R-(+)-HA-966, an antagonist for the glycine/NMDA receptor, prevents locomotor sensitization to repeated cocaine exposures.
Brain research 1995;673(1):165-9.
1995: Taylor J R; Elsworth J D; Sladek J R; Collier T J; Roth R H; Redmond D E
Sham surgery does not ameliorate MPTP-induced behavioral deficits in monkeys.
Cell transplantation 1995;4(1):13-26.
1994: Davis M; Hitchcock J M; Bowers M B; Berridge C W; Melia K R; Roth R H
Stress-induced activation of prefrontal cortex dopamine turnover: blockade by lesions of the amygdala.
Brain research 1994;664(1-2):207-10.
1994: Horger B A; Taylor J R; Elsworth J D; Roth R H
Preexposure to, but not cotreatment with, the neurotensin antagonist SR 48692 delays the development of cocaine sensitization.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1994;11(3):215-22.
1994: Rasmusson A M; Goldstein L E; Deutch A Y; Bunney B S; Roth R H
5-HT1a agonist +/-8-OH-DPAT modulates basal and stress-induced changes in medial prefrontal cortical dopamine.
Synapse (New York, N.Y.) 1994;18(3):218-24.
1994: Iyer R N; Sprouse J S; Aghajanian G K; Roth R H; Bradberry C W
Tryptophan pretreatment augmentation of p-chloroamphetamine-induced serotonin and dopamine release and reduction of long-term neurotoxicity.
Biochemical pharmacology 1994;48(7):1501-8.
1994: Goldstein L E; Rasmusson A M; Bunney B S; Roth R H
The NMDA glycine site antagonist (+)-HA-966 selectively regulates conditioned stress-induced metabolic activation of the mesoprefrontal cortical dopamine but not serotonin systems: a behavioral, neuroendocrine, and neurochemical study in the rat.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(8):4937-50.
1994: Collier T J; Elsworth J D; Taylor J R; Sladek J R; Roth R H; Redmond D E
Peripheral nerve-dopamine neuron co-grafts in MPTP-treated monkeys: augmentation of tyrosine hydroxylase-positive fiber staining and dopamine content in host systems.
Neuroscience 1994;61(4):875-89.
1994: Elsworth J D; al-Tikriti M S; Sladek J R; Taylor J R; Innis R B; Redmond D E; Roth R H
Novel radioligands for the dopamine transporter demonstrate the presence of intrastriatal nigral grafts in the MPTP-treated monkey: correlation with improved behavioral function.
Experimental neurology 1994;126(2):300-4.
1994: Youngren K D; Moghaddam B; Bunney B S; Roth R H
Preferential activation of dopamine overflow in prefrontal cortex produced by chronic clozapine treatment.
Neuroscience letters 1994;165(1-2):41-4.
1994: Kontur P J; al-Tikriti M; Innis R B; Roth R H
Postmortem stability of monoamines, their metabolites, and receptor binding in rat brain regions.
Journal of neurochemistry 1994;62(1):282-90.
1993: Sladek J R; Collier T J; Elsworth J D; Taylor J R; Roth R H; Redmond D E
Can graft-derived neurotrophic activity be used to direct axonal outgrowth of grafted dopamine neurons for circuit reconstruction in primates?
Experimental neurology 1993;124(1):134-9.
1993: Redmond D E; Roth R H; Spencer D D; Naftolin F; Leranth C; Robbins R J; Marek K L; Elsworth J D; Taylor J R; Sass K J
Neural transplantation for neurodegenerative diseases: past, present, and future.
Annals of the New York Academy of Sciences 1993;695():258-66.
1993: Morrow B A; Clark W A; Roth R H
Stress activation of mesocorticolimbic dopamine neurons: effects of a glycine/NMDA receptor antagonist.
European journal of pharmacology 1993;238(2-3):255-62.
1993: Elsworth J D; Taylor J R; Berger P; Roth R H
Cocaine-sensitive and -insensitive dopamine uptake in prefrontal cortex, nucleus accumbens and striatum.
Neurochemistry international 1993;23(1):61-9.
1993: Sladek J R; Elsworth J D; Roth R H; Evans L E; Collier T J; Cooper S J; Taylor J R; Redmond D E
Fetal dopamine cell survival after transplantation is dramatically improved at a critical donor gestational age in nonhuman primates.
Experimental neurology 1993;122(1):16-27.
1993: Kontur P J; Leranth C; Redmond D E; Roth R H; Robbins R J
Tyrosine hydroxylase immunoreactivity and monoamine and metabolite levels in cryopreserved human fetal ventral mesencephalon.
Experimental neurology 1993;121(2):172-80.
1993: Bradberry C W; Nobiletti J B; Elsworth J D; Murphy B; Jatlow P; Roth R H
Cocaine and cocaethylene: microdialysis comparison of brain drug levels and effects on dopamine and serotonin.
Journal of neurochemistry 1993;60(4):1429-35.
1993: Moghaddam B; Berridge C W; Goldman-Rakic P S; Bunney B S; Roth R H
In vivo assessment of basal and drug-induced dopamine release in cortical and subcortical regions of the anesthetized primate.
Synapse (New York, N.Y.) 1993;13(3):215-22.
1993: Redmond D E; Robbins R J; Naftolin F; Marek K L; Vollmer T L; Leranth C; Roth R H; Price L H; Gjedde A; Bunney B S
Cellular replacement of dopamine deficit in Parkinson's disease using human fetal mesencephalic tissue: preliminary results in four patients.
Research publications - Association for Research in Nervous and Mental Disease 1993;71():325-59.
1992: Spencer D D; Robbins R J; Naftolin F; Marek K L; Vollmer T; Leranth C; Roth R H; Price L H; Gjedde A; Bunney B S
Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease.
The New England journal of medicine 1992;327(22):1541-8.
1992: Strowbridge B W; Bean A J; Spencer D D; Roth R H; Shepherd G M; Robbins R J
Low levels of somatostatin-like immunoreactivity in neocortex resected from presumed seizure foci in epileptic patients.
Brain research 1992;587(1):164-8.
1992: Bustos G; Abarca J; Forray M I; Gysling K; Bradberry C W; Roth R H
Regulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum: in vivo microdialysis studies.
Brain research 1992;585(1-2):105-15.
1992: During M J; Bean A J; Roth R H
Effects of CNS stimulants on the in vivo release of the colocalized transmitters, dopamine and neurotensin, from rat prefrontal cortex.
Neuroscience letters 1992;140(1):129-33.
1992: Rosin D L; Clark W A; Goldstein M; Roth R H; Deutch A Y
Effects of 6-hydroxydopamine lesions of the prefrontal cortex on tyrosine hydroxylase activity in mesolimbic and nigrostriatal dopamine systems.
Neuroscience 1992;48(4):831-9.
1992: Grobin A C; Roth R H; Deutch A Y
Regulation of the prefrontal cortical dopamine system by the neuroactive steroid 3a,21-dihydroxy-5a-pregnane-20-one.
Brain research 1992;578(1-2):351-6.
1992: al-Tikriti M S; Roth R H; Kessler R M; Innis R B
Autoradiographic localization of dopamine D1 and D2 receptors in rat cerebral cortex following unilateral neurotoxic lesions.
Brain research 1992;575(1):39-46.
1992: During M J; Freese A; Deutch A Y; Kibat P G; Sabel B A; Langer R; Roth R H
Biochemical and behavioral recovery in a rodent model of Parkinson's disease following stereotactic implantation of dopamine-containing liposomes.
Experimental neurology 1992;115(2):193-9.
1992: Bean A J; Roth R H
Dopamine-neurotensin interactions in mesocortical neurons. Evidence from microdialysis studies.
Annals of the New York Academy of Sciences 1992;668():43-53.
1991: Lovenberg T W; Roth R H; Nichols D E; Mailman R B
D1 dopamine receptors of NS20Y neuroblastoma cells are functionally similar to rat striatal D1 receptors.
Journal of neurochemistry 1991;57(5):1563-9.
1991: Elsworth J D; Lawrence M S; Roth R H; Taylor J R; Mailman R B; Nichols D E; Lewis M H; Redmond D E
D1 and D2 dopamine receptors independently regulate spontaneous blink rate in the vervet monkey.
The Journal of pharmacology and experimental therapeutics 1991;259(2):595-600.
1991: Bean A J; Roth R H
Extracellular dopamine and neurotensin in rat prefrontal cortex in vivo: effects of median forebrain bundle stimulation frequency, stimulation pattern, and dopamine autoreceptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(9):2694-702.
1991: Bradberry C W; Gruen R J; Berridge C W; Roth R H
Individual differences in behavioral measures: correlations with nucleus accumbens dopamine measured by microdialysis.
Pharmacology, biochemistry, and behavior 1991;39(4):877-82.
1991: Lovenberg T W; Nichols D E; Nestler E J; Roth R H; Mailman R B
Guanine nucleotide binding proteins and the regulation of cyclic AMP synthesis in NS20Y neuroblastoma cells: role of D1 dopamine and muscarinic receptors.
Brain research 1991;556(1):101-7.
1991: Ida Y; Elsworth J D; Roth R H
Anxiogenic beta-carboline FG 7142 produces activation of noradrenergic neurons in specific brain regions of rats.
Pharmacology, biochemistry, and behavior 1991;39(3):791-3.
1991: Taylor J R; Lawrence M S; Redmond D E; Elsworth J D; Roth R H; Nichols D E; Mailman R B
Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-induced parkinsonism in monkeys.
European journal of pharmacology 1991;199(3):389-91.
1991: Bean A J; Roth R H
Effects of haloperidol administration on in vivo extracellular dopamine in striatum and prefrontal cortex after partial dopamine lesions.
Brain research 1991;549(1):155-8.
1991: Bradberry C W; Lory J D; Roth R H
The anxiogenic beta-carboline FG 7142 selectively increases dopamine release in rat prefrontal cortex as measured by microdialysis.
Journal of neurochemistry 1991;56(3):748-52.
1991: Bradberry C W; Sprouse J S; Sheldon P W; Aghajanian G K; Roth R H
In vitro microdialysis: a novel technique for stimulated neurotransmitter release measurements.
Journal of neuroscience methods 1991;36(1):85-90.
1991: Taylor J R; Lewis V O; Elsworth J D; Pivirotto P; Roth R H; Redmond D E
Yohimbine co-treatment during chronic morphine administration attenuates naloxone-precipitated withdrawal without diminishing tail-flick analgesia in rats.
Psychopharmacology 1991;103(3):407-14.
1991: Jatlow P; Elsworth J D; Bradberry C W; Winger G; Taylor J R; Russell R; Roth R H
Cocaethylene: a neuropharmacologically active metabolite associated with concurrent cocaine-ethanol ingestion.
Life sciences 1991;48(18):1787-94.
1991: Taylor J R; Elsworth J D; Roth R H; Sladek J R; Collier T J; Redmond D E
Grafting of fetal substantia nigra to striatum reverses behavioral deficits induced by MPTP in primates: a comparison with other types of grafts as controls.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1991;85(2):335-48.
1991: During M J; Heyes M P; Freese A; Swartz K J; Matson W R; Markey S P; Martin J B; Roth R H
Indolic and kynurenine pathway metabolites of tryptophan in rat brain: effect of precursor availability on in vivo release.
Advances in experimental medicine and biology 1991;294():535-9.
1991: Lawrence M S; Redmond D E; Elsworth J D; Taylor J R; Roth R H
The D1 receptor antagonist, SCH 23390, induces signs of parkinsonism in African green monkeys.
Life sciences 1991;49(25):PL229-34.
1991: Bradberry C W; Sprouse J S; Aghajanian G K; Roth R H
Sub-picogram determination of serotonin using HPLC with electrochemical detection for microdialysis studies of serotonin release.
Advances in experimental medicine and biology 1991;294():81-9.
1990: Deutch A Y; Elsworth J D; Roth R H; Goldstein M;
3-Acetylpyridine results in degeneration of the extrapyramidal and cerebellar motor systems: loss of the dorsolateral striatal dopamine innervation.
Brain research 1990;527(1):96-102.
1990: Redmond D E; Leranth C; Spencer D D; Robbins R; Vollmer T; Kim J H; Roth R H; Dwork A J; Naftolin F
Fetal neural graft survival.
Lancet 1990;336(8718):820-2.
1990: Taylor J R; Roth R H; Sladek J R; Redmond D E
Cognitive and motor deficits in the performance of an object retrieval task with a barrier-detour in monkeys (Cercopithecus aethiops sabaeus) treated with MPTP: long-term performance and effect of transparency of the barrier.
Behavioral neuroscience 1990;104(4):564-76.
1990: Elsworth J D; Deutch A Y; Redmond D E; Sladek J R; Roth R H
MPTP reduces dopamine and norepinephrine concentrations in the supplementary motor area and cingulate cortex of the primate.
Neuroscience letters 1990;114(3):316-22.
1990: Taylor J R; Elsworth J D; Roth R H; Sladek J R; Redmond D E
Cognitive and motor deficits in the acquisition of an object retrieval/detour task in MPTP-treated monkeys.
Brain : a journal of neurology 1990;113 ( Pt 3)():617-37.
1990: Deutch A Y; Clark W A; Roth R H
Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress.
Brain research 1990;521(1-2):311-5.
1990: Moghaddam B; Gruen R J; Roth R H; Bunney B S; Adams R N
Effect of L-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies.
Brain research 1990;518(1-2):55-60.
1990: Gruen R J; Deutch A Y; Roth R H
Perinatal diazepam exposure: alterations in exploratory behavior and mesolimbic dopamine turnover.
Pharmacology, biochemistry, and behavior 1990;36(1):169-75.
1990: Elsworth J D; Deutch A Y; Redmond D E; Sladek J R; Roth R H
MPTP-induced parkinsonism: relative changes in dopamine concentration in subregions of substantia nigra, ventral tegmental area and retrorubral field of symptomatic and asymptomatic vervet monkeys.
Brain research 1990;513(2):320-4.
1990: Gruen R J; Elsworth J D; Roth R H
Regionally specific alterations in the low-affinity GABAA receptor following perinatal exposure to diazepam.
Brain research 1990;514(1):151-4.
1990: Tam S Y; Roth R H
Modulation of mesoprefrontal dopamine neurons by central benzodiazepine receptors. I. Pharmacological characterization.
The Journal of pharmacology and experimental therapeutics 1990;252(3):989-96.
1990: Sprouse J S; Bradberry C W; Roth R H; Aghajanian G K
3,4-Methylenedioxymethamphetamine-induced release of serotonin and inhibition of dorsal raphe cell firing: potentiation by L-tryptophan.
European journal of pharmacology 1990;178(3):313-20.
1990: Robbins R J; Torres-Aleman I; Lebranth C; Bradberry C W; Deutch A Y; Welsh S; Roth R H; Spencer D; Redmond D E; Naftolin F
Cryopreservation of human brain tissue.
Experimental neurology 1990;107(3):208-13.
1990: Berger P; Elsworth J D; Reith M E; Tanen D; Roth R H
Complex interaction of cocaine with the dopamine uptake carrier.
European journal of pharmacology 1990;176(2):251-2.
1990: Berger P; Elsworth J D; Arroyo J; Roth R H
Interaction of [3H]GBR 12935 and GBR 12909 with the dopamine uptake complex in nucleus accumbens.
European journal of pharmacology 1990;177(1-2):91-4.
1990: Bean A J; During M J; Roth R H
Effects of dopamine autoreceptor stimulation on the release of colocalized transmitters: in vivo release of dopamine and neurotensin from rat prefrontal cortex.
Neuroscience letters 1990;108(1-2):143-8.
1990: Tam S Y; Elsworth J D; Bradberry C W; Roth R H
Mesocortical dopamine neurons: high basal firing frequency predicts tyrosine dependence of dopamine synthesis.
Journal of neural transmission. General section 1990;81(2):97-110.
1990: Taylor J R; Elsworth J D; Roth R H; Collier T J; Sladek J R; Redmond D E
Improvements in MPTP-induced object retrieval deficits and behavioral deficits after fetal nigral grafting in monkeys.
Progress in brain research 1990;82():543-59.
1990: Moghaddam B; Roth R H; Bunney B S
Characterization of dopamine release in the rat medial prefrontal cortex as assessed by in vivo microdialysis: comparison to the striatum.
Neuroscience 1990;36(3):669-76.
1990: Wolf M E; Roth R H
Autoreceptor regulation of dopamine synthesis.
Annals of the New York Academy of Sciences 1990;604():323-43.
1990: Deutch A Y; Roth R H
The determinants of stress-induced activation of the prefrontal cortical dopamine system.
Progress in brain research 1990;85():367-402; discussion 402-3.
1990: Jatlow P; Hearn W L; Elsworth J D; Roth R H; Bradberry C W; Taylor J R
Cocaethylene inhibits uptake of dopamine and can reach high plasma concentrations following combined cocaine and ethanol use.
NIDA research monograph 1990;105():572-3.
1989: Bean A J; During M J; Deutch A Y; Roth R H
Effects of dopamine depletion on striatal neurotensin: biochemical and immunohistochemical studies.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(12):4430-8.
1989: Sesack S R; Deutch A Y; Roth R H; Bunney B S
Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: an anterograde tract-tracing study with Phaseolus vulgaris leucoagglutinin.
The Journal of comparative neurology 1989;290(2):213-42.
1989: Yurek D M; Deutch A Y; Roth R H; Sladek J R
Morphological, neurochemical, and behavioral characterizations associated with the combined treatment of diethyldithiocarbamate and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
Brain research 1989;497(2):250-9.
1989: Bradberry C W; Roth R H
Cocaine increases extracellular dopamine in rat nucleus accumbens and ventral tegmental area as shown by in vivo microdialysis.
Neuroscience letters 1989;103(1):97-102.
1989: Knorr A M; Deutch A Y; Roth R H
The anxiogenic beta-carboline FG-7142 increases in vivo and in vitro tyrosine hydroxylation in the prefrontal cortex.
Brain research 1989;495(2):355-61.
1989: Sprouse J S; Bradberry C W; Roth R H; Aghajanian G K
MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin.
European journal of pharmacology 1989;167(3):375-83.
1989: Bean A J; During M J; Roth R H
Stimulation-induced release of coexistent transmitters in the prefrontal cortex: an in vivo microdialysis study of dopamine and neurotensin release.
Journal of neurochemistry 1989;53(2):655-7.
1989: Deutch A Y; Rosin D L; Goldstein M; Roth R H
3-Acetylpyridine-induced degeneration of the nigrostriatal dopamine system: an animal model of olivopontocerebellar atrophy-associated parkinsonism.
Experimental neurology 1989;105(1):1-9.
1989: Deutch A Y; Gruen R J; Roth R H
The effects of perinatal diazepam exposure on stress-induced activation of the mesotelencephalic dopamine system.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1989;2(2):105-14.
1989: Bean A J; Adrian T E; Modlin I M; Roth R H
Dopamine and neurotensin storage in colocalized and noncolocalized neuronal populations.
The Journal of pharmacology and experimental therapeutics 1989;249(3):681-7.
1989: During M J; Freese A; Sabel B A; Saltzman W M; Deutch A; Roth R H; Langer R
Controlled release of dopamine from a polymeric brain implant: in vivo characterization.
Annals of neurology 1989;25(4):351-6.
1989: During M J; Freese A; Heyes M P; Swartz K J; Markey S P; Roth R H; Martin J B
Neuroactive metabolites of L-tryptophan, serotonin and quinolinic acid, in striatal extracellular fluid. Effect of tryptophan loading.
FEBS letters 1989;247(2):438-44.
1989: During M J; Heyes M P; Freese A; Markey S P; Martin J B; Roth R H
Quinolinic acid concentrations in striatal extracellular fluid reach potentially neurotoxic levels following systemic L-tryptophan loading.
Brain research 1989;476(2):384-7.
1989: Sladek J R; Redmond D E; Collier T J; Elsworth J D; Roth R H
Transplantation advances in Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 1989;4 Suppl 1():S120-5.
1989: Elsworth J D; Deutch A Y; Redmond D E; Taylor J R; Sladek J R; Roth R H
Symptomatic and asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates: biochemical changes in striatal regions.
Neuroscience 1989;33(2):323-31.
1989: Bradberry C W; Karasic D H; Deutch A Y; Roth R H
Regionally-specific alterations in mesotelencephalic dopamine synthesis in diabetic rats: association with precursor tyrosine.
Journal of neural transmission. General section 1989;78(3):221-9.
1988: Bean A J; Shepard P D; Bunney B S; Nestler E J; Roth R H
The effects of pertussis toxin on autoreceptor-mediated inhibition of dopamine synthesis in the rat striatum.
Molecular pharmacology 1988;34(6):715-8.
1988: Goldstein M; Lieberman A N; Helmer E; Koslow M; Ransohoff J; Elsworth J D; Roth R H; Deutch A Y
Biochemical analysis of caudate nucleus biopsy samples from parkinsonian patients.
Annals of neurology 1988;24(5):685-8.
1988: Redmond D E; Naftolin F; Collier T J; Leranth C; Robbins R J; Sladek C D; Roth R H; Sladek J R
Cryopreservation, culture, and transplantation of human fetal mesencephalic tissue into monkeys.
Science (New York, N.Y.) 1988;242(4879):768-71.
1988: Sladek J R; Redmond D E; Roth R H
Transplantation of fetal neurons in primates.
Clinical research 1988;36(3):200-4.
1988: Deutch A Y; Bean A J; Roth R H
Regulation of A8 dopamine neurons by somatostatin.
European journal of pharmacology 1988;147(2):317-20.
1988: Sladek J R; Redmond D E; Collier T J; Blount J P; Elsworth J D; Taylor J R; Roth R H
Fetal dopamine neural grafts: extended reversal of methylphenyltetrahydropyridine-induced parkinsonism in monkeys.
Progress in brain research 1988;78():497-506.
1988: Collier T J; Sladek C D; Gallagher M J; Blanchard B C; Daley B F; Foster P N; Redmond D E; Roth R H; Sladek J R
Cryopreservation of fetal rat and non-human primate mesencephalic neurons: viability in culture and neural transplantation.
Progress in brain research 1988;78():631-6.
1988: Taylor J R; Elsworth J D; Garcia E J; Grant S J; Roth R H; Redmond D E
Clonidine infusions into the locus coeruleus attenuate behavioral and neurochemical changes associated with naloxone-precipitated withdrawal.
Psychopharmacology 1988;96(1):121-34.
1988: Roth R H; Tam S Y; Ida Y; Yang J X; Deutch A Y
Stress and the mesocorticolimbic dopamine systems.
Annals of the New York Academy of Sciences 1988;537():138-47.
1988: Deutch A Y; Goldstein M; Baldino F; Roth R H
Telencephalic projections of the A8 dopamine cell group.
Annals of the New York Academy of Sciences 1988;537():27-50.
1987: Collier T J; Redmond D E; Sladek C D; Gallagher M J; Roth R H; Sladek J R
Intracerebral grafting and culture of cryopreserved primate dopamine neurons.
Brain research 1987;436(2):363-6.
1987: Deutch A Y; Holliday J; Roth R H; Chun L L; Hawrot E
Immunohistochemical localization of a neuronal nicotinic acetylcholine receptor in mammalian brain.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8697-701.
1987: Wolf M E; Roth R H
Dopamine neurons projecting to the medial prefrontal cortex possess release-modulating autoreceptors.
Neuropharmacology 1987;26(8):1053-9.
1987: Deutch A Y; Bean A J; Bissette G; Nemeroff C B; Robbins R J; Roth R H
Stress-induced alterations in neurotensin, somatostatin and corticotropin-releasing factor in mesotelencephalic dopamine system regions.
Brain research 1987;417(2):350-4.
1987: Elsworth J D; Deutch A Y; Redmond D E; Sladek J R; Roth R H
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on catecholamines and metabolites in primate brain and CSF.
Brain research 1987;415(2):293-9.
1987: Ida Y; Roth R H
The activation of mesoprefrontal dopamine neurons by FG 7142 is absent in rats treated chronically with diazepam.
European journal of pharmacology 1987;137(2-3):185-90.
1987: Murrin L C; Roth R H
Nigrostriatal dopamine neurons: modulation of impulse-induced activation of tyrosine hydroxylation by dopamine autoreceptors.
Neuropharmacology 1987;26(6):591-5.
1987: Deutch A Y; Tam S Y; Freeman A S; Bowers M B; Roth R H
Mesolimbic and mesocortical dopamine activation induced by phencyclidine: contrasting pattern to striatal response.
European journal of pharmacology 1987;134(3):257-64.
1987: Deutch A Y; Roth R H
Calcitonin gene-related peptide in the ventral tegmental area: selective modulation of prefrontal cortical dopamine metabolism.
Neuroscience letters 1987;74(2):169-74.
1987: Elsworth J D; Deutch A Y; Redmond D E; Sladek J R; Roth R H
Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum.
Life sciences 1987;40(2):193-202.
1987: Elsworth J D; Leahy D J; Roth R H; Redmond D E
Homovanillic acid concentrations in brain, CSF and plasma as indicators of central dopamine function in primates.
Journal of neural transmission 1987;68(1-2):51-62.
1987: Sladek J R; Redmond D E; Collier T J; Haber S N; Elsworth J D; Deutch A Y; Roth R H
Transplantation of fetal dopamine neurons in primate brain reverses MPTP induced parkinsonism.
Progress in brain research 1987;71():309-23.
1987: Sladek J R; Collier T J; Haber S N; Deutch A Y; Elsworth J D; Roth R H; Redmond D E
Reversal of parkinsonism by fetal nerve cell transplants in primate brain.
Annals of the New York Academy of Sciences 1987;495():641-57.
1986: Sladek J R; Collier T J; Haber S N; Roth R H; Redmond D E
Survival and growth of fetal catecholamine neurons transplanted into primate brain.
Brain research bulletin 1986;17(6):809-18.
1986: Deutch A Y; Goldstein M; Roth R H
The ascending projections of the dopaminergic neurons of the substantia nigra, zona reticulata: a combined retrograde tracer-immunohistochemical study.
Neuroscience letters 1986;71(3):257-63.
1986: Redmond D E; Sladek J R; Roth R H; Collier T J; Elsworth J D; Deutch A Y; Haber S
Transplants of primate neurons.
Lancet 1986;2(8514):1046.
1986: Bannon M J; Deutch A Y; Tam S Y; Zamir N; Eskay R L; Lee J M; Maggio J E; Roth R H
Mild footshock stress dissociates substance P from substance K and dynorphin from Met- and Leu-enkephalin.
Brain research 1986;381(2):393-6.
1986: Deutch A Y; Elsworth J D; Goldstein M; Fuxe K; Redmond D E; Sladek J R; Roth R H
Preferential vulnerability of A8 dopamine neurons in the primate to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Neuroscience letters 1986;68(1):51-6.
1986: Knorr A M; Wolf M E; Roth R H
K+-dependent stimulation of tyrosine hydroxylation in striatal slices: role of Ca2+/calmodulin and Ca2+/phospholipid-dependent mechanisms.
Biochemical pharmacology 1986;35(12):1929-32.
1986: Redmond D E; Sladek J R; Roth R H; Collier T J; Elsworth J D; Deutch A Y; Haber S
Fetal neuronal grafts in monkeys given methylphenyltetrahydropyridine.
Lancet 1986;1(8490):1125-7.
1986: Lee J M; McLean S; Maggio J E; Zamir N; Roth R H; Eskay R L; Bannon M J
The localization and characterization of substance P and substance K in striatonigral neurons.
Brain research 1986;371(1):152-4.
1986: Galloway M P; Wolf M E; Roth R H
Regulation of dopamine synthesis in the medial prefrontal cortex is mediated by release modulating autoreceptors: studies in vivo.
The Journal of pharmacology and experimental therapeutics 1986;236(3):689-98.
1986: Wolf M E; Galloway M P; Roth R H
Regulation of dopamine synthesis in the medial prefrontal cortex: studies in brain slices.
The Journal of pharmacology and experimental therapeutics 1986;236(3):699-707.
1986: Deutch A Y; Goldstein M; Roth R H
Activation of the locus coeruleus induced by selective stimulation of the ventral tegmental area.
Brain research 1986;363(2):307-14.
1986: Kafka M S; Benedito M A; Roth R H; Steele L K; Wolfe W W; Catravas G N
Circadian rhythms in catecholamine metabolites and cyclic nucleotide production.
Chronobiology international 1986;3(2):101-15.
1985: Kalivas P W; Deutch A Y; Maggio J E; Mantyh P W; Roth R H
Substance K and substance P in the ventral tegmental area.
Neuroscience letters 1985;57(3):241-6.
1985: Tam S Y; Roth R H
Selective increase in dopamine metabolism in the prefrontal cortex by the anxiogenic beta-carboline FG 7142.
Biochemical pharmacology 1985;34(9):1595-8.
1985: Deutch A Y; Tam S Y; Roth R H
Footshock and conditioned stress increase 3,4-dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra.
Brain research 1985;333(1):143-6.
1985: Wolf M E; Roth R H
Dopamine autoreceptor stimulation increases protein carboxyl methylation in striatal slices.
Journal of neurochemistry 1985;44(1):291-8.
1985: Grant S J; Galloway M P; Mayor R; Fenerty J P; Finkelstein M F; Roth R H; Redmond D E
Precipitated diazepam withdrawal elevates noradrenergic metabolism in primate brain.
European journal of pharmacology 1985;107(2):127-32.
1985: Deutch A Y; Maggio J E; Bannon M J; Kalivas P W; Tam S Y; Goldstein M; Roth R H
Substance K and substance P differentially modulate mesolimbic and mesocortical systems.
Peptides 1985;6 Suppl 2():113-22.
1984: Charney D S; Redmond D E; Galloway M P; Kleber H D; Heninger G R; Murberg M; Roth R H
Naltrexone precipitated opiate withdrawal in methadone addicted human subjects: evidence for noradrenergic hyperactivity.
Life sciences 1984;35(12):1263-72.
1984: Chiodo L A; Bannon M J; Grace A A; Roth R H; Bunney B S
Evidence for the absence of impulse-regulating somatodendritic and synthesis-modulating nerve terminal autoreceptors on subpopulations of mesocortical dopamine neurons.
Neuroscience 1984;12(1):1-16.
1984: Roth R H
CNS dopamine autoreceptors: distribution, pharmacology, and function.
Annals of the New York Academy of Sciences 1984;430():27-53.
1983: Galloway M P; Roth R H
Neuropharmacology of 3-isobutylmethylxanthine: effects on central noradrenergic systems in vivo.
The Journal of pharmacology and experimental therapeutics 1983;227(1):1-8.
1983: Elsworth J D; Roth R H; Redmond D E
Relative importance of 3-methoxy-4-hydroxyphenylglycol and 3,4-dihydroxyphenylglycol as norepinephrine metabolites in rat, monkey, and humans.
Journal of neurochemistry 1983;41(3):786-93.
1983: Reinhard J F; Galloway M P; Roth R H
Noradrenergic modulation of serotonin synthesis and metabolism. II. Stimulation by 3-isobutyl-1-methylxanthine.
The Journal of pharmacology and experimental therapeutics 1983;226(3):764-9.
1983: Bannon M J; Wolf M E; Roth R H
Pharmacology of dopamine neurons innervating the prefrontal, cingulate and piriform cortices.
European journal of pharmacology 1983;92(1-2):119-25.
1983: Sternberg D E; Heninger G R; Roth R H
Plasma homovanillic acid as an index of brain dopamine metabolism: enhancement with debrisoquin.
Life sciences 1983;32(21):2447-52.
1983: Billingsley M L; Velletri P A; Roth R H; DeLorenzo R J
Carboxylmethylation of calmodulin inhibits calmodulin-dependent phosphorylation in rat brain membranes and cytosol.
The Journal of biological chemistry 1983;258(9):5352-7.
1983: Bannon M J; Roth R H
Pharmacology of mesocortical dopamine neurons.
Pharmacological reviews 1983;35(1):53-68.
1983: Galloway M P; Roth R H
Clonidine prevents methylxanthine stimulation of norepinephrine metabolism in rat brain.
Journal of neurochemistry 1983;40(1):246-51.
1982: Billingsley M L; Roth R H
Dopamine agonists stimulate protein carboxylmethylation in striatal synaptosomes.
The Journal of pharmacology and experimental therapeutics 1982;223(3):681-8.
1982: Holcomb H H; Bannon M J; Roth R H
Striatal dopamine autoreceptors uninfluenced by chronic administration of antidepressants.
European journal of pharmacology 1982;82(3-4):173-8.
1982: Kendler K S; Heninger G R; Roth R H
Influence of dopamine agonists on plasma and brain levels of homovanillic acid.
Life sciences 1982;30(24):2063-9.
1982: Roth R H; Elsworth J D; Redmond D E
Clonidine suppression of noradrenergic hyperactivity during morphine withdrawal by clonidine: biochemical studies in rodents and primates.
The Journal of clinical psychiatry 1982;43(6 Pt 2):42-6.
1982: Bannon M J; Reinhard J F; Bunney E B; Roth R H
Unique response to antipsychotic drugs is due to absence of terminal autoreceptors in mesocortical dopamine neurones.
Nature 1982;296(5856):444-6.
1982: Bacopoulos N G; Bustos G; Redmond D E; Roth R H
Chronic treatment with haloperidol or fluphenazine decanoate: regional effects on dopamine and serotonin metabolism in primate brain.
The Journal of pharmacology and experimental therapeutics 1982;221(1):22-8.
1982: Elsworth J D; Redmond D E; Roth R H
Plasma and cerebrospinal fluid 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) as indices of brain norepinephrine metabolism in primates.
Brain research 1982;235(1):115-24.
1982: Reinhard J F; Bannon M J; Roth R H
Acceleration by stress of dopamine synthesis and metabolism in prefrontal cortex: antagonism by diazepam.
Naunyn-Schmiedeberg's archives of pharmacology 1982;318(4):374-7.
1981: Riker D K; Zito R A; Roth R H
Lidocaine selectively diminishes medullary serotonin metabolism in the rat.
Neuropharmacology 1981;20(12A):1233-6.
1981: Charney D S; Heninger G R; Sternberg D E; Redmond D E; Leckman J F; Maas J W; Roth R H
Presynaptic adrenergic receptor sensitivity in depression. The effect of long-term desipramine treatment.
Archives of general psychiatry 1981;38(12):1334-40.
1981: Michaud R L; Bannon M J; Roth R H
The use of c8-octyl columns for the analysis of catecholamines by ion-pair reversed-phase liquid chromatography with amperometric detection.
Journal of chromatography 1981;225(2):335-45.
1981: Riker D K; Messer A; Roth R H
Increased noradrenergic metabolism in the cerebellum of the mouse mutant dystonia musculorum.
Journal of neurochemistry 1981;37(3):649-54.
1981: Bannon M J; Bunney E B; Roth R H
Mesocortical dopamine neurons: rapid transmitter turnover compared to other brain catecholamine systems.
Brain research 1981;218(1-2):376-82.
1981: Kendler K S; Heninger G R; Roth R H
Brain contribution to the haloperidol-induced increase in plasma homovanillic acid.
European journal of pharmacology 1981;71(2-3):321-6.
1981: Zigun J R; Bannon M J; Roth R H
Comparison of two alpha-noradrenergic agonists (clonidine and guanfacine) on norepinephrine turnover in the cortex of rats during morphine abstinence.
European journal of pharmacology 1981;70(4):565-70.
1981: Bannon M J; Michaud R L; Roth R H
Mesocortical dopamine neurons. Lack of autoreceptors modulating dopamine synthesis.
Molecular pharmacology 1981;19(2):270-5.
1981: Bacopoulos N G; Roth R H
Apomorphine-haloperidol interactions: different types of antagonism in cortical and subcortical brain regions.
Brain research 1981;205(2):313-9.
1981: Braszko J J; Bannon M J; Bunney B S; Roth R H
Intrastriatal kainic acid: acute effects on electrophysiological and biochemical measures of nigrostriatal dopaminergic activity.
The Journal of pharmacology and experimental therapeutics 1981;216(2):289-93.
1981: Riker D K; Roth R H; Breakefield X O
High-affinity [3H]choline accumulation in cultured human skin fibroblasts.
Journal of neurochemistry 1981;36(2):746-52.
1981: Swann A C; Heninger G R; Roth R H; Maas J W
Differential effects of short and long term lithium on tryptophan uptake and serotonergic function in cat brain.
Life sciences 1981;28(4):347-54.
1980: Umezu K; Bustos G; Roth R H
Regional inhibitory effect of ethanol on monoamine synthesis regulation within the brain.
Biochemical pharmacology 1980;29(18):2477-83.
1980: Bustos G; Simon J; Roth R H
Tyrosine hydroxylase regulation: apparent kinetic alterations following incubation of brain slices in a sodium-free medium.
Journal of neurochemistry 1980;35(1):47-57.
1980: Wheeler S C; Roth R H
Tolerance to fluphenazine and supersensitivity to apomorphine in central dopaminergic systems after chronic fluphenazine decanoate treatment.
Naunyn-Schmiedeberg's archives of pharmacology 1980;312(2):151-9.
1980: Bannon M J; Bunney E B; Zigun J R; Skirboll L R; Roth R H
Presynaptic dopamine receptors: insensitivity to kainic acid and the development of supersensitivity following chronic haloperidol.
Naunyn-Schmiedeberg's archives of pharmacology 1980;312(2):161-5.
1980: Roth R H; Doherty J D; Walters J R
Gamma-hydroxybutyrate: a role in the regulation of central dopaminergic neurons?
Brain research 1980;189(2):556-60.
1980: Bannon M J; Grace A A; Bunney B S; Roth R H
Evidence for an irreversible interaction of bromocryptine with central dopamine receptors.
Naunyn-Schmiedeberg's archives of pharmacology 1980;312(1):37-41.
1980: Marek K L; Roth R H
Ergot alkaloids: interaction with presynaptic dopamine receptors in the neostriatum and olfactory tubercles.
European journal of pharmacology 1980;62(2-3):137-46.
1980: Laverty R; Roth R H
Clonidine reverses the increased norepinephrine turnover during morphine withdrawal in rats.
Brain research 1980;182(2):482-5.
1980: Bacopoulos N G; Redmond D E; Baulu J; Roth R H
Chronic haloperidol or fluphenazine: effects on dopamine metabolism in brain, cerebrospinal fluid and plasma of Cercopithecus aethiops (vervet monkey).
The Journal of pharmacology and experimental therapeutics 1980;212(1):1-5.
1980: Salzman P M; Roth R H
Poststimulation catecholamine synthesis and tyrosine hydroxylase activation in central noradrenergic neurons. I. In vivo stimulation of the locus coeruleus.
The Journal of pharmacology and experimental therapeutics 1980;212(1):64-73.
1980: Roth R H; Bacopoulos N G; Bustos G; Redmond D E
Antipsychotic drugs: differential effects on dopamine neurons in basal ganglia and mesocortex following chronic administration in human and nonhuman primates.
Advances in biochemical psychopharmacology 1980;24():513-20.
1979: Wang R Y; de Montigny C; Gold B I; Roth R H; Aghajanian G K
Denervation supersensitivity to serotonin in rat forebrain: single cell studies.
Brain research 1979;178(2-3):479-97.
1979: Riker D K; Sastre A; Baker T; Roth R H; Riker W F
Regional high-affinity [3H]choline accumulation in cat forebrain: selective increase in the caudate-putamen after corticosteroid pretreatment.
Molecular pharmacology 1979;16(3):886-99.
1979: Nowycky M C; Roth R H
Chronic gamma-butyrolactone (GBL) treatment: a potential model of dopamine hypoactivity.
Naunyn-Schmiedeberg's archives of pharmacology 1979;309(3):247-54.
1979: Bustos G; Roth R H
Does cyclic AMP-dependent phosphorylation account for the activation of tyrosine hydroxylase produced by depolarization of central dopaminergic neurons?
Biochemical pharmacology 1979;28(19):3026-8.
1979: Bacopoulos N C; Spokes E G; Bird E D; Roth R H
Antipsychotic drug action in schizophrenic patients: effect on cortical dopamine metabolism after long-term treatment.
Science (New York, N.Y.) 1979;205(4413):1405-7.
1979: Simon J R; Roth R H
Striatal tyrosine hydroxylase: comparison of the activation produced by depolarization and dibutyryl-cAMP.
Molecular pharmacology 1979;16(1):224-33.
1979: Bacopoulos N G; Hattox S E; Roth R H
3,4-Dihydroxyphenylacetic acid and homovanillic acid in rat plasma: possible indicators of central dopaminergic activity.
European journal of pharmacology 1979;56(3):225-36.
1979: Bustos G; Roth R H
Tyrosine hydroxylase regulation in rat striatal and olfactory tubercle slices--I. Activation induced by exposure to a calcium-free and high-magnesium medium.
Biochemical pharmacology 1979;28(12):1923-31.
1979: Bacopoulos N G; Redmond D E; Roth R H
Serotonin and dopamine metabolites in brain regions and cerebrospinal fluid of a primate species: effects of ketamine and fluphenazine.
Journal of neurochemistry 1979;32(4):1215-8.
1979: Gold B I; Roth R H
Glutamate decarboxylase activity in striatal slices: characterization of the increase following depolarization.
Journal of neurochemistry 1979;32(3):883-8.
1979: Ando N; Simon J R; Roth R H
Inverse relationship between GABA and gamma-hydroxybutyrate levels in striatum of rat injected with kainic acid.
Journal of neurochemistry 1979;32(2):623-5.
1979: Ando N; Gold B I; Bird E D; Roth R H
Regional brain levels of gamma-hydroxybutyrate in Huntington's disease.
Journal of neurochemistry 1979;32(2):617-22.
1979: Hegstrand L R; Simon J R; Roth R H
Tyrosine hydroxylase:--examination of conditions influencing activity in pheochromocytoma, adrenal medulla and striatum.
Biochemical pharmacology 1979;28(4):519-23.
1978: Bacopoulos N G; Bustos G; Redmond D E; Baulu J; Roth R H
Regional sensitivity of primate brain dopaminergic neurons to haloperidol: alterations following chronic treatment.
Brain research 1978;157(2):396-401.
1978: Bacopoulos N G; Heninger G R; Roth R H
Effects of haloperidol and probenecid on plasma and CSF dopamine metabolites in the rhesus monkey (Macacca mulatta).
Life sciences 1978;23(17-18):1805-12.
1978: Doherty J D; Roth R H
Metabolism of gamma-hydroxy-[1-14C] butyrate by rat brain: relationship to the Krebs cycle and metabolic compartmentation of amino acids.
Journal of neurochemistry 1978;30(6):1305-9.
1978: Simon J R; Hegstrand L R; Roth R H
Regulation of tyrosine hydroxylase from human pheochromocytoma, bovine adrenal and rat striatum.
Life sciences 1978;22(5):421-8.
1978: Gold B I; Simon J R; Roth R H
Glutamic acid decarboxylase activity in striatal slices: persistent increase following depolarization.
Life sciences 1978;22(2):187-93.
1978: Choi R L; Roth R H
Development of supersensitivity of apomorphine-induced increases in acetylcholine levels and stereotype after chronic fluphenazine treatment.
Neuropharmacology 1978;17(1):59-64.
1978: Bustos G; Roth R H; Morgenroth V H; Hancke J L
Tyrosine hydroxylase activation and transmitter release from central noradrenergic neurons by electrical field stimulation.
Naunyn-Schmiedeberg's archives of pharmacology 1978;301(3):149-56.
1978: Nowycky M C; Walters J R; Roth R H
Dopaminergic neurons: effect of acute and chronic morphine administration on single cell activity and transmitter metabolism.
Journal of neural transmission 1978;42(2):99-116.
1978: Bacopoulos N G; Maas J W; Hattox S E; Roth R H
Regional distribution of dopamine metabolites in human and primate brain.
Communications in psychopharmacology 1978;2(4):281-6.
1977: Maas J W; Hattox S E; Landis D H; Roth R H
A direct method for studying 3-methoxy-4-hydroxyphenethyleneglycol (MHPG) production by brain in awake animals.
European journal of pharmacology 1977;46(3):221-8.
1977: Rawe S E; Copeland P M; Roth R H
Segmental norepinephrine and dopamine levels in cat spinal cord.
Life sciences 1977;21(10):1409-16.
1977: Roth R H; Nowycky M C
Dopaminergic neurons: effects elicited by gamma-hydroxybutyrate are reversed by picrotoxin.
Biochemical pharmacology 1977;26(21):2079-82.
1977: Bacopoulos N G; Hattox S E; Roth R H
Effects of nigrostriatal pathway stimulation and tropolone on plasma concentration of 3,4-dihydroxyphenylacetic acid.
Biochemical pharmacology 1977;26(22):2197-9.
1977: Gold B I; Roth R H
Kinetics of in vivo conversion of gamma-[3H]aminobutyric acid to gamma-[3H]hydroxybutyric acid by rat brain.
Journal of neurochemistry 1977;28(5):1069-73.
1977: Rawe S E; Roth R H; Boadle-Biber M; Collins W F
Norepinephrine levels in experimental spinal cord trauma. Part 1: Biochemical study of hemorrhagic necrosis.
Journal of neurosurgery 1977;46(3):342-9.
1977: Elchisak M A; Maas J W; Roth R H
Dihydroxyphenylacetic acid conjugate: natural occurrence and demonstration of probenecid-induced accumulation in rat striatum, olfactory tubercles and frontal cortex.
European journal of pharmacology 1977;41(4):369-78.
1977: Roth R H; Nowycky M C; Walters J R; Morgenroth V H
gamma-Hydroxybutyrate: effects on nonstriatal dopaminergic neurons.
Advances in biochemical psychopharmacology 1977;16():483-8.
1977: Roth R H; Nowycky M C
Nonstriatal dopaminergic neurons: role of presynaptic receptors in the modulation of transmitter synthesis.
Advances in biochemical psychopharmacology 1977;16():465-70.
1976: Maas J W; Hattox S E; Landis D H; Roth R H
The determination of a brain arteriovenous difference for 3-methoxy-4-hydroxyphenethyleneglycol (MHPG).
Brain research 1976;118(1):167-73.
1976: Walters J R; Roth R H
Dopaminergic neurons: an in vivo system for measuring drug interactions with presynaptic receptors.
Naunyn-Schmiedeberg's archives of pharmacology 1976;296(1):5-14.
1976: Murrin L C; Morgenroth V H; Roth R H
Dopaminergic neurons: effects of electrical stimulation on tyrosine hydroxylase.
Molecular pharmacology 1976;12(6):1070-81.
1976: Bustos G; Roth R H; Morgenroth V H
Activation of tyrosine hydroxylase in rat striatal slices by K+-depolarization--effect of ethanol.
Biochemical pharmacology 1976;25(22):2493-7.
1976: Sethy V H; Roth R H; Walters J R; Marini J; Van Woert M H
Effect of anesthetic doses of gamma-hydroxybutyrate on the acetylcholine content of rat brain.
Naunyn-Schmiedeberg's archives of pharmacology 1976;295(1):9-14.
1976: Murrin L C; Roth R H
Dopaminergic neurons: reversal of effects elicited by gamma-butyrolactone by stimulation of the nigro-neostriatal pathway.
Naunyn-Schmiedeberg's archives of pharmacology 1976;295(1):15-20.
1976: Krueger B K; Forn J; Walters J R; Roth R H; Greengard P
Stimulation by dopamine of adenosine cyclic 3',5'-monophosphate formation in rat caudate nucleus: effect of lesions of the nigro-neostriatal pathway.
Molecular pharmacology 1976;12(4):639-48.
1976: Bustos G; Roth R H
Effect of acute ethanol treatment on transmitter synthesis and metabolism in central dopaminergic neurons.
The Journal of pharmacy and pharmacology 1976;28(7):580-2.
1976: Murrin L C; Roth R H
Dopaminergic neurons: effects of electrical stimulation on dopamine biosynthesis.
Molecular pharmacology 1976;12(3):463-75.
1976: Extein I; Van Woert M; Roth R H; Bowers M B
14C-homovanillic acid in the cerebrospinal fluid of parkinsonian patients after intravenous 14C-L-dopa.
Biological psychiatry 1976;11(2):227-32.
1976: Roth R H; Murrin L C; Walters J R
Central dopaminergic neurons: effects of alterations in impulse flow on the accumulation of dihydroxyphenylacetic acid.
European journal of pharmacology 1976;36(1):163-71.
1976: Morgenroth V H; Walters J R; Roth R H
Dopaminergic neurons--alteration in the kinetic properties of tyrosine hydroxylase after cessation of impulse flow.
Biochemical pharmacology 1976;25(6):655-61.
1976: Walters J R; Roth R H
Dopaminergic neurons - alteration in the sensitivity of tyrosine hydroxylase to inhibition by endovenous dopamine after cessation of impulse flow.
Biochemical pharmacology 1976;25(6):649-54.
1976: Morgenroth V H; Boadle-Biber M C; Roth R H
Dopaminergic neurons: activation of tyrosine hydroxylase by a calcium chelator.
Molecular pharmacology 1976;12(1):41-8.
1976: Roth R H
Striatal dopamine and gamma-hydroxybutyrate.
Pharmacology & therapeutics. Part B: General & systematic pharmacology 1976;2(1):71-88.
1976: Elchisak M A; Murrin L C; Roth R H; Maas J W
Free and conjugated dihydroxyphenylacetic acid: effect of alterations in impulse flow in rat neostriatum and frontal cortex.
Psychopharmacology communications 1976;2(5-6):411-20.
1975: Noon J P; McAfee D A; Roth R H
Norepinephrine release from nerve terminals within the rabbit superior cervical ganglion.
Naunyn-Schmiedeberg's archives of pharmacology 1975;291(2):139-62.
1975: Herr B E; Gallager D W; Roth R H
Tryptophan hydroxylase: activation in vivo following stimulation of central serotonergic neurons.
Biochemical pharmacology 1975;24(21):2019-23.
1975: Roth R H; Walters J R; Murrin L C; Morgenroth V H
Dopamine neurons: role of impulse flow and presynaptic receptors in the regulation of tyrosine hydroxylase.
Psychopharmacology bulletin 1975;11(4):8.
1975: Boadle-Biber M C; Roth R H
Formation of dopamine and noradrenaline in rat vas deferens: comparison with guinea-pig vas deferens.
British journal of pharmacology 1975;55(1):73-8.
1975: Roth R H; Morgenroth V H; Salzman P M
Tyrosine hydroxylase: allosteric activation induced by stimulation of central noradrenergic neurons.
Naunyn-Schmiedeberg's archives of pharmacology 1975;289(4):327-43.
1975: Nybäck H V; Walters J R; Aghajanian G K; Roth R H
Tricyclic antidepressants: effects on the firing rate of brain noradrenergic neurons.
European journal of pharmacology 1975;32(02):302-12.
1975: Nowycky M C; Sgaragli G P; Cooper J R; Roth R H
Effect of collagenase on the release of dopamine and acetylcholine from slices of rat corpus striatum.
Journal of neurochemistry 1975;24(6):1279-81.
1975: Roth R H
Gamma-hydroxybutyrate and control of dopaminergic neurons.
Psychopharmacology bulletin 1975;11(2):57-8.
1975: Harris J E; Baldessarini R J; Morgenroth V H; Roth R H
Activation by cyclic 3':5'-adenosine monophosphate of tyrosine hydroxylase in the rat brain.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(3):789-93.
1975: Morgenroth V H; Hegstrand L R; Roth R H; Greengard P
Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase.
The Journal of biological chemistry 1975;250(5):1946-8.
1975: Doherty J D; Stout R W; Roth R H
Metabolism of (1-14C)gamma-hydroxybutyric acid by rat brain after intraventricular injection.
Biochemical pharmacology 1975;24(4):469-74.
1975: Bunney B S; Roth R H; Aghajanian G K
Effects of molindone on central dopaminergic neuronal activity and metabolism: similarity to other neuroleptics.
Psychopharmacology communications 1975;1(4):349-58.
1975: Bunney B S; Walters J R; Kuhar M J; Roth R H; Aghajanian G K
D & L amphetamine stereoisomers: comparative potencies in affecting the firing of central dopaminergic and noradrenergic neurons.
Psychopharmacology communications 1975;1(2):177-90.
1975: Walters J R; Bunney B S; Roth R H
Piribedil and apomorphine: pre- and postsynaptic effects on dopamine synthesis and neuronal activity.
Advances in neurology 1975;9():273-84.
1974: Harris J E; Morgenroth V H; Roth R H; Baldessarini R J
Regulation of catecholamine synthesis in the rat brain in vitro by cyclic AMP.
Nature 1974;252(5479):156-8.
1974: Extein I; Roth R H; Bowers M B
Accumulation of 3H-homovanillic acid in rabbit brain and cerebrospinal fluid following intravenous 3H-L-dopa.
Biological psychiatry 1974;9(2):161-70.
1974: Walters J R; Roth R H
Dopaminergic neurons: drug-induced antagonism of the increase in tyrosine hydroxylase activity produced by cessation of impulse flow.
The Journal of pharmacology and experimental therapeutics 1974;191(1):82-91.
1974: Roth R H; Salzman P M; Morgenroth V H
Noradrenergic neurons: allosteric activation of hippocampal tyrosine hydroxylase by stimulation of the locus coeruleus.
Biochemical pharmacology 1974;23(19):2779-84.
1974: Roth R H; Walters J R; Morgenroth V H
Proceedings: Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons.
Psychopharmacology bulletin 1974;10(3):40.
1974: Kuhar M J; Aghajanian G K; Roth R H
Serotonin neurons: a synaptic mechanism for the reuptake of serotonin.
Advances in biochemical psychopharmacology 1974;10():287-95.
1974: Roth R H; Walters J R; Morgenroth V H
Effects of alterations in impulse flow on transmitter metabolism in central dopaminergic neurons.
Advances in biochemical psychopharmacology 1974;12(0):369-84.
1973: Sethy V H; Roth R H; Kuhar M J; Van Woert M H
Choline and acetylcholine: regional distribution and effect of degeneration of cholinergic nerve terminals in the rat hippocampus.
Neuropharmacology 1973;12(9):819-23.
1973: Walters J R; Roth R H; Aghajanian G K
Dopaminergic neurons: similar biochemical and histochemical effects of gamma-hydroxybutyrate and acute lesions of the nigro-neostriatal pathway.
The Journal of pharmacology and experimental therapeutics 1973;186(3):630-9.
1973: Bunney B S; Aghajanian G K; Roth R H
Comparison of effects of L-dopa, amphetamine and apomorphine on firing rate of rat dopaminergic neurones.
Nature: New biology 1973;245(143):123-5.
1973: Wilson W S; Roth R H; Cooper J R
The subcellular localization of noradrenaline and dopamine in bovine superior cervical ganglion.
Life sciences 1973;13(4):281-5.
1973: Bunney B S; Walters J R; Roth R H; Aghajanian G K
Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.
The Journal of pharmacology and experimental therapeutics 1973;185(3):560-71.
1973: Sethy V H; Kuhar M J; Roth R H; Van Woert M H; Aghajanian G K
Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus.
Brain research 1973;55(2):481-4.
1973: Extein I; Korf J; Roth R H; Bowers M B
Accumulation of 3-methoxy-4-hydroxyphenylglycol-sulfate in rabbit cerebrospinal fluid following probenecid.
Brain research 1973;54():403-7.
1973: Korf J; Aghajanian G K; Roth R H
Stimulation and destruction of the locus coeruleus: opposite effects on 3-methoxy-4-hydroxyphenylglycol sulfate levels in the rat cerebral cortex.
European journal of pharmacology 1973;21(3):305-10.
1973: Kuhar M J; Sethy V H; Roth R H; Aghajanian G K
Choline: selective accumulation by central cholinergic neurons.
Journal of neurochemistry 1973;20(2):581-93.
1972: Roth R H; Hughes J
Acceleration of protein synthesis by angiotensin--correlation with angiotensin's effect on catecholamine biosynthesis.
Biochemical pharmacology 1972;21(23):3182-7.
1972: Bustos G; Kuhar M J; Roth R H
Effect of gamma-hydroxybutyrate and gamma-butyrolactone on dopamine synthesis and uptake by rat striatum.
Biochemical pharmacology 1972;21(19):2649-52.
1972: Bustos G; Roth R H
Release of monoamines from the striatum and hypothalamus: effect of -hydroxybutyrate.
British journal of pharmacology 1972;46(1):101-15.
1972: Kuhar M J; Aghajanian G K; Roth R H
Tryptophan hydroxylase activity and synaptosomal uptake of serotonin in discrete brain regions after midbrain raphe lesions: correlations with serotonin levels and histochemical fluorescence.
Brain research 1972;44(1):165-76.
1972: Kuhar M J; Roth R H; Aghajanian G K
Synthesis of catecholamines in the locus coeruleus from 3 H-tyrosine in vivo.
Biochemical pharmacology 1972;21(16):2280-2.
1972: Walters J R; Roth R H
Effect of gamma-hydroxybutyrate on dopamine and dopamine metabolites in the rat striatum.
Biochemical pharmacology 1972;21(15):2111-21.
1972: Maxwell R; Roth R H
Conversion of 1,4-butanediol to -hydroxybutyric acid in rat brain and in peripheral tissue.
Biochemical pharmacology 1972;21(11):1521-33.
1972: Bustos G; Roth R H
Effect of -hydroxybutyrate on the release of monoamines from the rat striatum.
British journal of pharmacology 1972;44(4):817-20.
1972: Kuhar M J; Roth R H; Aghajanian G K
Synaptosomes from forebrains of rats with midbrain raphe lesions: selective reduction of serotonin uptake.
The Journal of pharmacology and experimental therapeutics 1972;181(1):36-45.
1972: Bowers M B; Roth R H
Interaction of atropine-like drugs with dopamine-containing neurones in rat brain.
British journal of pharmacology 1972;44(2):301-6.
1971: Harris J E; Roth R H
Potassium-induced acceleration of catecholamine biosynthesis in brain slices. I. A study of the mechanism of action.
Molecular pharmacology 1971;7(6):593-604.
1971: Roth R H
Effect of anesthetic doses of hydroxybutyrate on subcortical concentrations of homovanillic acid.
European journal of pharmacology 1971;15(1):52-9.
1970: Roth R H
Formation and regional distribution of gamma-hydroxybutyric acid in mammalian brain.
Biochemical pharmacology 1970;19(12):3013-9.
1970: Roth R H; Suhr Y
Mechanism of the gamma-hydroxybutyrate-induced increase in brain dopamine and its relationship to "sleep".
Biochemical pharmacology 1970;19(12):3001-12.
1970: Aghajanian G K; Roth R H
Gamma-hydroxybutyrate-induced increase in brain dopamine: localization by fluorescence microscopy.
The Journal of pharmacology and experimental therapeutics 1970;175(1):131-8.
1970: DeFeudis F V; Delgado J M; Roth R H
Content, synthesis and collectability of amino acids in various structures of the brains of rhesus monkeys.
Brain research 1970;18(1):15-23.
1970: Stjärne L; Roth R H; Bloom F E; Giarman N J
Norepinephrine concentrating mechanisms in sympathetic nerve trunks.
The Journal of pharmacology and experimental therapeutics 1970;171(1):70-9.
1969: Roth R H; Allikmets L; Delgado J M
Synthesis and release of noradrenaline and dopamine from discrete regiions of monkey brain.
Archives internationales de pharmacodynamie et de thérapie 1969;181(2):273-82.
1969: Roth R H; Giarman N J
Conversion in vivo of gamma-aminobutyric to gamma-hydroxybutyric acid in the rat.
Biochemical pharmacology 1969;18(1):247-50.
1968: Roth R H
The action of chlorpromazine on tyrosine hydroxylase in postganglionic sympathetic nerve.
Life sciences 1968;7(17):951-4.
1968: Roth R H; Giarman N J
Evidence that central nervous system depression by 1,4-butanediol in mediated through a metabolite, gamma-hydroxybutyrate.
Biochemical pharmacology 1968;17(5):735-9.
1967: Stjärne L; Roth R H; Lishajko F
Noradrenaline formation from dopamine in isolated subcellular particles from bovine splenic nerve.
Biochemical pharmacology 1967;16(9):1729-39.
1967: Stjärne L; Lishajko F; Roth R H
Regulation of noradrenaline biosynthesis in nerve tissue.
Nature 1967;215(5102):770-2.
1966: Roth R H; Delgado J M; Giarman N J
Gamma-butyrolactone and gamma-hydroxybutyric acid. II. The pharmacologically active form.
International journal of neuropharmacology 1966;5(6):421-8.
1966: Roth R H; Stjärne L; von Euler U S
Acceleration of noradrenaline biosynthesis by nerve stimulation.
Life sciences 1966;5(12):1071-5.
1965: ROTH R H; GIARMAN N J
PRELIMINARY REPORT ON THE METABOLISM OF GAMMA-BUTYROLACTONE AND GAMMA-HYDROXYBUTYRIC ACID.
Biochemical pharmacology 1965;14():177-8.
1964: GIARMAN N J; ROTH R H
DIFFERENTIAL ESTIMATION OF GAMMA-BUTYROLACTONE AND GAMMA-HYDROXYBUTYRIC ACID IN RAT BLOOD AND BRAIN.
Science (New York, N.Y.) 1964;145():583-4.

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