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Douglas Rothman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Magnetic Resonance Spectroscopy

Chemicals & Drugs

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Publications

TOP 3
Chahboune Halima; Ment Laura R; Stewart William B; Rothman Douglas L; Vaccarino Flora M; Hyder Fahmeed; Schwartz Michael L
Hypoxic injury during neonatal development in murine brain: correlation between in vivo DTI findings and behavioral assessment.
Shulman Robert G; Hyder Fahmeed; Rothman Douglas L
Baseline brain energy supports the state of consciousness.
Jiang Lihong; Herzog Raimund I; Mason Graeme F; de Graaf Robin A; Rothman Douglas L; Sherwin Robert S; Behar Kevin L
Recurrent antecedent hypoglycemia alters neuronal oxidative metabolism in vivo.

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All Publications

2009: Chahboune Halima; Ment Laura R; Stewart William B; Rothman Douglas L; Vaccarino Flora M; Hyder Fahmeed; Schwartz Michael L
Hypoxic injury during neonatal development in murine brain: correlation between in vivo DTI findings and behavioral assessment.
Cerebral cortex (New York, N.Y. : 1991) 2009;19(12):2891-901.
2009: Shulman Robert G; Hyder Fahmeed; Rothman Douglas L
Baseline brain energy supports the state of consciousness.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(27):11096-101.
2009: Jiang Lihong; Herzog Raimund I; Mason Graeme F; de Graaf Robin A; Rothman Douglas L; Sherwin Robert S; Behar Kevin L
Recurrent antecedent hypoglycemia alters neuronal oxidative metabolism in vivo.
Diabetes 2009;58(6):1266-74.
2009: van Eijsden Pieter; Hyder Fahmeed; Rothman Douglas L; Shulman Robert G
Neurophysiology of functional imaging.
NeuroImage 2009;45(4):1047-54.
2009: de Graaf Robin A; Chowdhury Golam M I; Brown Peter B; Rothman Douglas L; Behar Kevin L
In situ 3D magnetic resonance metabolic imaging of microwave-irradiated rodent brain: a new tool for metabolomics research.
Journal of neurochemistry 2009;109(2):494-501.
2009: Befroy Douglas E; Falk Petersen Kitt; Rothman Douglas L; Shulman Gerald I
Assessment of in vivo mitochondrial metabolism by magnetic resonance spectroscopy.
Methods in enzymology 2009;457():373-93.
2008: Chowdhury Golam M I; Banasr Mounira; de Graaf Robin A; Rothman Douglas L; Behar Kevin L; Sanacora Gerard
Chronic riluzole treatment increases glucose metabolism in rat prefrontal cortex and hippocampus.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(12):1892-7.
2008: Befroy Douglas E; Petersen Kitt Falk; Dufour Sylvie; Mason Graeme F; Rothman Douglas L; Shulman Gerald I
Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(43):16701-6.
2008: de Graaf Robin A; Brown Peter B; Rothman Douglas L; Behar Kevin L
Natural abundance (17)O NMR spectroscopy of rat brain in vivo.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2008;193(1):63-7.
2008: Nixon Terence W; McIntyre Scott; Rothman Douglas L; de Graaf Robin A
Compensation of gradient-induced magnetic field perturbations.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2008;192(2):209-17.
2008: Maciejewski Paul K; Rothman Douglas L
Proposed cycles for functional glutamate trafficking in synaptic neurotransmission.
Neurochemistry international 2008;52(4-5):809-25.
2007: Chowdhury Golam M I; Patel Anant B; Mason Graeme F; Rothman Douglas L; Behar Kevin L
Glutamatergic and GABAergic neurotransmitter cycling and energy metabolism in rat cerebral cortex during postnatal development.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(12):1895-907.
2007: de Graaf Robin A; Rothman Douglas L; Behar Kevin L
High resolution NMR spectroscopy of rat brain in vivo through indirect zero-quantum-coherence detection.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2007;187(2):320-6.
2007: Petersen Kitt Falk; Dufour Sylvie; Savage David B; Bilz Stefan; Solomon Gina; Yonemitsu Shin; Cline Gary W; Befroy Douglas; Zemany Laura; Kahn Barbara B; Papademetris Xenophon; Rothman Douglas L; Shulman Gerald I
The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(31):12587-94.
2007: Shulman Robert G; Rothman Douglas L; Hyder Fahmeed
A BOLD search for baseline.
NeuroImage 2007;36(2):277-81.
2007: Chahboune Halima; Ment Laura R; Stewart William B; Ma Xiaoxian; Rothman Douglas L; Hyder Fahmeed
Neurodevelopment of C57B/L6 mouse brain assessed by in vivo diffusion tensor imaging.
NMR in biomedicine 2007;20(3):375-82.
2007: Befroy Douglas E; Petersen Kitt Falk; Dufour Sylvie; Mason Graeme F; de Graaf Robin A; Rothman Douglas L; Shulman Gerald I
Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients.
Diabetes 2007;56(5):1376-81.
2007: Kida Ikuhiro; Rothman Douglas L; Hyder Fahmeed
Dynamics of changes in blood flow, volume, and oxygenation: implications for dynamic functional magnetic resonance imaging calibration.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(4):690-6.
2007: Koch Kevin M; Sacolick Laura I; Nixon Terence W; McIntyre Scott; Rothman Douglas L; de Graaf Robin A
Dynamically shimmed multivoxel 1H magnetic resonance spectroscopy and multislice magnetic resonance spectroscopic imaging of the human brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2007;57(3):587-91.
2007: Sacolick Laura I; Rothman Douglas L; de Graaf Robin A
Adiabatic refocusing pulses for volume selection in magnetic resonance spectroscopic imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2007;57(3):548-53.
2007: Mason Graeme F; Petersen Kitt Falk; de Graaf Robin A; Shulman Gerald I; Rothman Douglas L
Measurements of the anaplerotic rate in the human cerebral cortex using 13C magnetic resonance spectroscopy and [1-13C] and [2-13C] glucose.
Journal of neurochemistry 2007;100(1):73-86.
2006: Koch Kevin M; Papademetris Xenophon; Rothman Douglas L; de Graaf Robin A
Rapid calculations of susceptibility-induced magnetostatic field perturbations for in vivo magnetic resonance.
Physics in medicine and biology 2006;51(24):6381-402.
2006: Koch Kevin M; Brown Peter B; Rothman Douglas L; de Graaf Robin A
Sample-specific diamagnetic and paramagnetic passive shimming.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2006;182(1):66-74.
2006: de Graaf Robin A; Brown Peter B; McIntyre Scott; Nixon Terence W; Behar Kevin L; Rothman Douglas L
High magnetic field water and metabolite proton T1 and T2 relaxation in rat brain in vivo.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(2):386-94.
2006: Schafer James R; Kida Ikuhiro; Xu Fuqiang; Rothman Douglas L; Hyder Fahmeed
Reproducibility of odor maps by fMRI in rodents.
NeuroImage 2006;31(3):1238-46.
2006: Hyder Fahmeed; Patel Anant B; Gjedde Albert; Rothman Douglas L; Behar Kevin L; Shulman Robert G
Neuronal-glial glucose oxidation and glutamatergic-GABAergic function.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(7):865-77.
2006: Epperson C Neill; Gueorguieva Ralitza; Czarkowski Kathryn A; Stiklus Stephanie; Sellers Edward; Krystal John H; Rothman Douglas L; Mason Graeme F
Preliminary evidence of reduced occipital GABA concentrations in puerperal women: a 1H-MRS study.
Psychopharmacology 2006;186(3):425-33.
2006: Koch Kevin M; McIntyre Scott; Nixon Terence W; Rothman Douglas L; de Graaf Robin A
Dynamic shim updating on the human brain.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2006;180(2):286-96.
2006: de Graaf Robin A; Patel Anant B; Rothman Douglas L; Behar Kevin L
Acute regulation of steady-state GABA levels following GABA-transaminase inhibition in rat cerebral cortex.
Neurochemistry international 2006;48(6-7):508-14.
2006: Mason Graeme F; Petersen Kitt F; Lebon Vincent; Rothman Douglas L; Shulman Gerald I
Increased brain monocarboxylic acid transport and utilization in type 1 diabetes.
Diabetes 2006;55(4):929-34.
2006: Petroff Ognen A C; Hyder Fahmeed; Rothman Douglas L; Mattson Richard H
Brain homocarnosine and seizure control of patients taking gabapentin or topiramate.
Epilepsia 2006;47(3):495-8.
2006: Sanacora Gerard; Fenton Lisa R; Fasula Madonna K; Rothman Douglas L; Levin Yael; Krystal John H; Mason Graeme F
Cortical gamma-aminobutyric acid concentrations in depressed patients receiving cognitive behavioral therapy.
Biological psychiatry 2006;59(3):284-6.
2006: Mason Graeme F; Petrakis Ismene L; de Graaf Robin A; Gueorguieva Ralitza; Guidone Elizabeth; Coric Vladimir; Epperson C Neill; Rothman Douglas L; Krystal John H
Cortical gamma-aminobutyric acid levels and the recovery from ethanol dependence: preliminary evidence of modification by cigarette smoking.
Biological psychiatry 2006;59(1):85-93.
2005: Xu Fuqiang; Schaefer Michele; Kida Ikuhiro; Schafer James; Liu Nian; Rothman Douglas L; Hyder Fahmeed; Restrepo Diego; Shepherd Gordon M
Simultaneous activation of mouse main and accessory olfactory bulbs by odors or pheromones.
The Journal of comparative neurology 2005;489(4):491-500.
2005: Schafer James R; Kida Ikuhiro; Rothman Douglas L; Hyder Fahmeed; Xu Fuqiang
Adaptation in the rodent olfactory bulb measured by fMRI.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;54(2):443-8.
2005: Safriel Yair; Pol-Rodriguez Marlyanne; Novotny Edward J; Rothman Douglas L; Fulbright Robert K
Reference values for long echo time MR spectroscopy in healthy adults.
AJNR. American journal of neuroradiology 2005;26(6):1439-45.
2005: Patel Anant B; de Graaf Robin A; Mason Graeme F; Rothman Douglas L; Shulman Robert G; Behar Kevin L
The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(15):5588-93.
2005: Epperson C Neill; O'Malley Stephanie; Czarkowski Kathryn A; Gueorguieva Ralitza; Jatlow Peter; Sanacora Gerard; Rothman Douglas L; Krystal John H; Mason Graeme F
Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy.
Biological psychiatry 2005;57(1):44-8.
2005: Patel Anant B; Chowdhury Golam M I; de Graaf Robin A; Rothman Douglas L; Shulman Robert G; Behar Kevin L
Cerebral pyruvate carboxylase flux is unaltered during bicuculline-seizures.
Journal of neuroscience research 2005;79(1-2):128-38.
2004: Patel Anant B; de Graaf Robin A; Mason Graeme F; Kanamatsu Tomoyuki; Rothman Douglas L; Shulman Robert G; Behar Kevin L
Glutamatergic neurotransmission and neuronal glucose oxidation are coupled during intense neuronal activation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(9):972-85.
2004: de Graaf Robin A; Mason Graeme F; Patel Anant B; Rothman Douglas L; Behar Kevin L
Regional glucose metabolism and glutamatergic neurotransmission in rat brain in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(34):12700-5.
2004: Shulman Robert G; Rothman Douglas L; Behar Kevin L; Hyder Fahmeed
Energetic basis of brain activity: implications for neuroimaging.
Trends in neurosciences 2004;27(8):489-95.
2004: Sanacora Gerard; Gueorguieva Ralitza; Epperson C Neill; Wu Yu-Te; Appel Michael; Rothman Douglas L; Krystal John H; Mason Graeme F
Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression.
Archives of general psychiatry 2004;61(7):705-13.
2004: Nersesyan Hrachya; Hyder Fahmeed; Rothman Douglas L; Blumenfeld Hal
Dynamic fMRI and EEG recordings during spike-wave seizures and generalized tonic-clonic seizures in WAG/Rij rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(6):589-99.
2004: Mason Graeme F; Rothman Douglas L
Basic principles of metabolic modeling of NMR (13)C isotopic turnover to determine rates of brain metabolism in vivo.
Metabolic engineering 2004;6(1):75-84.
2003: Patel Anant B; De Graaf Robin A; Mason Graeme F; Rothman Douglas L; Shulman Robert G; Behar Kevin L
Coupling of glutamatergic neurotransmission and neuronal glucose oxidation over the entire range of cerebral cortex activity.
Annals of the New York Academy of Sciences 2003;1003():452-3.
2003: Sanacora Gerard; Rothman Douglas L; Mason Graeme; Krystal John H
Clinical studies implementing glutamate neurotransmission in mood disorders.
Annals of the New York Academy of Sciences 2003;1003():292-308.
2003: de Graaf Robin A; Mason Graeme F; Patel Anant B; Behar Kevin L; Rothman Douglas L
In vivo 1H-[13C]-NMR spectroscopy of cerebral metabolism.
NMR in biomedicine 2003;16(6-7):339-57.
2003: Xu Fuqiang; Liu Nian; Kida Ikuhiro; Rothman Douglas L; Hyder Fahmeed; Shepherd Gordon M
Odor maps of aldehydes and esters revealed by functional MRI in the glomerular layer of the mouse olfactory bulb.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):11029-34.
2003: Price Thomas B; Krishnan-Sarin Suchitra; Rothman Douglas L
Smoking impairs muscle recovery from exercise.
American journal of physiology. Endocrinology and metabolism 2003;285(1):E116-22.
2003: Petersen Kitt Falk; Befroy Douglas; Dufour Sylvie; Dziura James; Ariyan Charlotte; Rothman Douglas L; DiPietro Loretta; Cline Gary W; Shulman Gerald I
Mitochondrial dysfunction in the elderly: possible role in insulin resistance.
Science (New York, N.Y.) 2003;300(5622):1140-2.
2003: Shulman Robert G; Hyder Fahmeed; Rothman Douglas L
Cerebral metabolism and consciousness.
Comptes rendus biologies 2003;326(3):253-73.
2003: Sanacora Gerard; Mason Graeme F; Rothman Douglas L; Hyder Fahmeed; Ciarcia James J; Ostroff Robert B; Berman Robert M; Krystal John H
Increased cortical GABA concentrations in depressed patients receiving ECT.
The American journal of psychiatry 2003;160(3):577-9.
2003: de Graaf Robin A; Brown Peter B; McIntyre Scott; Rothman Douglas L; Nixon Terence W
Dynamic shim updating (DSU) for multislice signal acquisition.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;49(3):409-16.
2003: de Graaf Robin A; Rothman Douglas L; Behar Kevin L
Adiabatic RARE imaging.
NMR in biomedicine 2003;16(1):29-35.
2003: Mason Graeme F; Falk Petersen Kitt; de Graaf Robin A; Kanamatsu Tomoyuki; Otsuki Taisuke; Shulman Gerald I; Rothman Douglas L
A comparison of (13)C NMR measurements of the rates of glutamine synthesis and the tricarboxylic acid cycle during oral and intravenous administration of [1-(13)C]glucose.
Brain research. Brain research protocols 2003;10(3):181-90.
2003: de Graaf Robin A; Brown Peter B; Mason Graeme F; Rothman Douglas L; Behar Kevin L
Detection of [1,6-13C2]-glucose metabolism in rat brain by in vivo 1H-[13C]-NMR spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;49(1):37-46.
2003: Hyder Fahmeed; Kida Ikuhiro; Behar Kevin L; Kennan Richard P; Rothman Douglas L
Dominant events that modulate mass transfer coefficient of oxygen in cerebral cortex.
Advances in experimental medicine and biology 2003;530():401-11.
2003: Novotny Edward J; Fulbright Robert K; Pearl Phillip L; Gibson K Michael; Rothman Douglas L
Magnetic resonance spectroscopy of neurotransmitters in human brain.
Annals of neurology 2003;54 Suppl 6():S25-31.
2003: Rothman Douglas L; Behar Kevin L; Hyder Fahmeed; Shulman Robert G
In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: implications for brain function.
Annual review of physiology 2003;65():401-27.
2002: Petroff Ognen A C; Errante Laura D; Rothman Douglas L; Kim Jung H; Spencer Dennis D
Neuronal and glial metabolite content of the epileptogenic human hippocampus.
Annals of neurology 2002;52(5):635-42.
2002: Epperson C Neill; Haga Kristin; Mason Graeme F; Sellers Edward; Gueorguieva Ralitza; Zhang Wenjiang; Weiss Erica; Rothman Douglas L; Krystal John H
Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study.
Archives of general psychiatry 2002;59(9):851-8.
2002: Shulman Robert G; Hyder Fahmeed; Rothman Douglas L
Biophysical basis of brain activity: implications for neuroimaging.
Quarterly reviews of biophysics 2002;35(3):287-325.
2002: Hyder Fahmeed; Rothman Douglas L; Shulman Robert G
Total neuroenergetics support localized brain activity: implications for the interpretation of fMRI.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10771-6.
2002: Smith Arien J; Blumenfeld Hal; Behar Kevin L; Rothman Douglas L; Shulman Robert G; Hyder Fahmeed
Cerebral energetics and spiking frequency: the neurophysiological basis of fMRI.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10765-70.
2002: Petroff Ognen A C; Errante Laura D; Rothman Douglas L; Kim Jung H; Spencer Dennis D
Glutamate-glutamine cycling in the epileptic human hippocampus.
Epilepsia 2002;43(7):703-10.
2002: Sanacora Gerard; Mason Graeme F; Rothman Douglas L; Krystal John H
Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors.
The American journal of psychiatry 2002;159(4):663-5.
2002: Sinha Ranjana; Dufour Sylvie; Petersen Kitt Falk; LeBon Vincent; Enoksson Staffan; Ma Yong-Zhan; Savoye Mary; Rothman Douglas L; Shulman Gerald I; Caprio Sonia
Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity.
Diabetes 2002;51(4):1022-7.
2002: Lebon Vincent; Petersen Kitt F; Cline Gary W; Shen Jun; Mason Graeme F; Dufour Sylvie; Behar Kevin L; Shulman Gerald I; Rothman Douglas L
Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(5):1523-31.
2001: Hyder F; Kida I; Behar K L; Kennan R P; Maciejewski P K; Rothman D L
Quantitative functional imaging of the brain: towards mapping neuronal activity by BOLD fMRI.
NMR in biomedicine 2001;14(7-8):413-31.
2001: Shulman R G; Hyder F; Rothman D L
Lactate efflux and the neuroenergetic basis of brain function.
NMR in biomedicine 2001;14(7-8):389-96.
2001: Patel A B; Rothman D L; Cline G W; Behar K L
Glutamine is the major precursor for GABA synthesis in rat neocortex in vivo following acute GABA-transaminase inhibition.
Brain research 2001;919(2):207-20.
2001: Mason G F; Martin D L; Martin S B; Manor D; Sibson N R; Patel A; Rothman D L; Behar K L
Decrease in GABA synthesis rate in rat cortex following GABA-transaminase inhibition correlates with the decrease in GAD(67) protein.
Brain research 2001;914(1-2):81-91.
2001: Lebon V; Dufour S; Petersen K F; Ren J; Jucker B M; Slezak L A; Cline G W; Rothman D L; Shulman G I
Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle.
The Journal of clinical investigation 2001;108(5):733-7.
2001: Behar K L; Rothman D L
In vivo nuclear magnetic resonance studies of glutamate-gamma-aminobutyric acid-glutamine cycling in rodent and human cortex: the central role of glutamine.
The Journal of nutrition 2001;131(9 Suppl):2498S-504S; discussion 2523S-4S.
2001: de Graaf R A; Rothman D L
Detection of gamma-aminobutyric acid (GABA) by longitudinal scalar order difference editing.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2001;152(1):124-31.
2001: Shulman R G; Hyder F; Rothman D L
Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6417-22.
2001: de Graaf R A; Pan J W; Telang F; Lee J H; Brown P; Novotny E J; Hetherington H P; Rothman D L
Differentiation of glucose transport in human brain gray and white matter.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(5):483-92.
2001: Petroff O A; Hyder F; Rothman D L; Mattson R H
Topiramate rapidly raises brain GABA in epilepsy patients.
Epilepsia 2001;42(4):543-8.
2001: Chase J R; Rothman D L; Shulman R G
Flux control in the rat gastrocnemius glycogen synthesis pathway by in vivo 13C/31P NMR spectroscopy.
American journal of physiology. Endocrinology and metabolism 2001;280(4):E598-607.
2001: Petroff O A; Hyder F; Rothman D L; Mattson R H
Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures.
Neurology 2001;56(6):709-15.
2001: Sibson N R; Mason G F; Shen J; Cline G W; Herskovits A Z; Wall J E; Behar K L; Rothman D L; Shulman R G
In vivo (13)C NMR measurement of neurotransmitter glutamate cycling, anaplerosis and TCA cycle flux in rat brain during.
Journal of neurochemistry 2001;76(4):975-89.
2001: Shulman R G; Rothman D L
The "glycogen shunt" in exercising muscle: A role for glycogen in muscle energetics and fatigue.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(2):457-61.
2001: Shulman R G; Rothman D L
13C NMR of intermediary metabolism: implications for systemic physiology.
Annual review of physiology 2001;63():15-48.
2000: Petroff O A; Hyder F; Rothman D L; Mattson R H
Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients.
Epilepsia 2000;41(6):675-80.
2000: Kida I; Kennan R P; Rothman D L; Behar K L; Hyder F
High-resolution CMR(O2) mapping in rat cortex: a multiparametric approach to calibration of BOLD image contrast at 7 Tesla.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(5):847-60.
2000: Hyder F; Renken R; Kennan R P; Rothman D L
Quantitative multi-modal functional MRI with blood oxygenation level dependent exponential decays adjusted for flow attenuated inversion recovery (BOLDED AFFAIR).
Magnetic resonance imaging 2000;18(3):227-35.
2000: Krssak M; Petersen K F; Bergeron R; Price T; Laurent D; Rothman D L; Roden M; Shulman G I
Intramuscular glycogen and intramyocellular lipid utilization during prolonged exercise and recovery in man: a 13C and 1H nuclear magnetic resonance spectroscopy study.
The Journal of clinical endocrinology and metabolism 2000;85(2):748-54.
2000: Price T B; Laurent D; Petersen K F; Rothman D L; Shulman G I
Glycogen loading alters muscle glycogen resynthesis after exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;88(2):698-704.
2000: Petroff O A; Mattson R H; Rothman D L
Proton MRS: GABA and glutamate.
Advances in neurology 2000;83():261-71.
1999: Shen J; Rothman D L; Hetherington H P; Pan J W
Linear projection method for automatic slice shimming.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1999;42(6):1082-8.
1999: Hyder F; Renken R; Rothman D L
In vivo carbon-edited detection with proton echo-planar spectroscopic imaging (ICED PEPSI): [3,4-(13)CH(2)]glutamate/glutamine tomography in rat brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1999;42(6):997-1003.
1999: Price T B; Rothman D L; Shulman R G
NMR of glycogen in exercise.
The Proceedings of the Nutrition Society 1999;58(4):851-9.
1999: Sanacora G; Mason G F; Rothman D L; Behar K L; Hyder F; Petroff O A; Berman R M; Charney D S; Krystal J H
Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy.
Archives of general psychiatry 1999;56(11):1043-7.
1999: Verhoeff N P; Petroff O A; Hyder F; Zoghbi S S; Fujita M; Rajeevan N; Rothman D L; Seibyl J P; Mattson R H; Innis R B
Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS.
Epilepsia 1999;40(10):1433-8.
1999: Rothman D L; Sibson N R; Hyder F; Shen J; Behar K L; Shulman R G
In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate-glutamine neurotransmitter cycle and functional neuroenergetics.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1999;354(1387):1165-77.
1999: Cline G W; Petersen K F; Krssak M; Shen J; Hundal R S; Trajanoski Z; Inzucchi S; Dresner A; Rothman D L; Shulman G I
Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes.
The New England journal of medicine 1999;341(4):240-6.
1999: Petroff O A; Hyder F; Collins T; Mattson R H; Rothman D L
Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures.
Epilepsia 1999;40(7):958-64.
1999: Shen J; Petersen K F; Behar K L; Brown P; Nixon T W; Mason G F; Petroff O A; Shulman G I; Shulman R G; Rothman D L
Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):8235-40.
1999: Behar K L; Rothman D L; Petersen K F; Hooten M; Delaney R; Petroff O A; Shulman G I; Navarro V; Petrakis I L; Charney D S; Krystal J H
Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients.
The American journal of psychiatry 1999;156(6):952-4.
1999: Hyder F; Petroff O A; Mattson R H; Rothman D L
Localized 1H NMR measurements of 2-pyrrolidinone in human brain in vivo.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1999;41(5):889-96.
1999: Petroff O A; Rothman D L; Behar K L; Hyder F; Mattson R H
Effects of valproate and other antiepileptic drugs on brain glutamate, glutamine, and GABA in patients with refractory complex partial seizures.
Seizure : the journal of the British Epilepsy Association 1999;8(2):120-7.
1999: Novotny E J; Hyder F; Shevell M; Rothman D L
GABA changes with vigabatrin in the developing human brain.
Epilepsia 1999;40(4):462-6.
1999: Shulman R G; Rothman D L; Hyder F
Stimulated changes in localized cerebral energy consumption under anesthesia.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3245-50.
1999: Petroff O A; Hyder F; Mattson R H; Rothman D L
Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy.
Neurology 1999;52(3):473-8.
1999: Krssak M; Falk Petersen K; Dresner A; DiPietro L; Vogel S M; Rothman D L; Roden M; Shulman G I
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.
Diabetologia 1999;42(1):113-6.
1999: Shen J; Shungu D C; Rothman D L
In vivo chemical shift imaging of gamma-aminobutyric acid in the human brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1999;41(1):35-42.
1999: Dresner A; Laurent D; Marcucci M; Griffin M E; Dufour S; Cline G W; Slezak L A; Andersen D K; Hundal R S; Rothman D L; Petersen K F; Shulman G I
Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity.
The Journal of clinical investigation 1999;103(2):253-9.
1999: Hyder F; Shulman R G; Rothman D L
Regulation of cerebral oxygen delivery.
Advances in experimental medicine and biology 1999;471():99-110.
1999: Petroff O A; Behar K L; Rothman D L
New NMR measurements in epilepsy. Measuring brain GABA in patients with complex partial seizures.
Advances in neurology 1999;79():939-45.
1998: Petroff O A; Mattson R H; Behar K L; Hyder F; Rothman D L
Vigabatrin increases human brain homocarnosine and improves seizure control.
Annals of neurology 1998;44(6):948-52.
1998: Shen J; Novotny E J; Rothman D L
In vivo lactate and beta-hydroxybutyrate editing using a pure-phase refocusing pulse train.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1998;40(5):783-8.
1998: Shulman R G; Rothman D L
Interpreting functional imaging studies in terms of neurotransmitter cycling.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(20):11993-8.
1998: Hyder F; Shulman R G; Rothman D L
A model for the regulation of cerebral oxygen delivery.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;85(2):554-64.
1998: Petersen K F; Hendler R; Price T; Perseghin G; Rothman D L; Held N; Amatruda J M; Shulman G I
13C/31P NMR studies on the mechanism of insulin resistance in obesity.
Diabetes 1998;47(3):381-6.
1998: Petersen K F; Laurent D; Rothman D L; Cline G W; Shulman G I
Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans.
The Journal of clinical investigation 1998;101(6):1203-9.
1998: Petroff O A; Rothman D L
Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin.
Molecular neurobiology 1998;16(1):97-121.
1998: Sibson N R; Dhankhar A; Mason G F; Rothman D L; Behar K L; Shulman R G
Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(1):316-21.
1998: Shen J; Sibson N R; Cline G; Behar K L; Rothman D L; Shulman R G
15N-NMR spectroscopy studies of ammonia transport and glutamine synthesis in the hyperammonemic rat brain.
Developmental neuroscience 1998;20(4-5):434-43.
1998: Sibson N R; Shen J; Mason G F; Rothman D L; Behar K L; Shulman R G
Functional energy metabolism: in vivo 13C-NMR spectroscopy evidence for coupling of cerebral glucose consumption and glutamatergic neuronalactivity.
Developmental neuroscience 1998;20(4-5):321-30.
1997: Rothman D L; Behar K L; Prichard J W; Petroff O A
Homocarnosine and the measurement of neuronal pH in patients with epilepsy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1997;38(6):924-9.
1997: Shen J; Rycyna R E; Rothman D L
Improvements on an in vivo automatic shimming method [FASTERMAP].
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1997;38(5):834-9.
1997: Hyder F; Rothman D L; Mason G F; Rangarajan A; Behar K L; Shulman R G
Oxidative glucose metabolism in rat brain during single forepaw stimulation: a spatially localized 1H[13C] nuclear magnetic resonance study.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1997;17(10):1040-7.
1997: Shen J; Rothman D L
Fast automatic adjustment of on-axis shims for high-resolution NMR.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1997;127(2):229-32.
1997: Cline G W; Magnusson I; Rothman D L; Petersen K F; Laurent D; Shulman G I
Mechanism of impaired insulin-stimulated muscle glucose metabolism in subjects with insulin-dependent diabetes mellitus.
The Journal of clinical investigation 1997;99(9):2219-24.
1997: Sibson N R; Dhankhar A; Mason G F; Behar K L; Rothman D L; Shulman R G
In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2699-704.
1997: Shen J; Rothman D L
Adiabatic slice-selective excitation for surface coils.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1997;124(1):72-9.
1996: Petroff O A; Rothman D L; Behar K L; Mattson R H
Low brain GABA level is associated with poor seizure control.
Annals of neurology 1996;40(6):908-11.
1996: Petroff O A; Rothman D L; Behar K L; Collins T L; Mattson R H
Human brain GABA levels rise rapidly after initiation of vigabatrin therapy.
Neurology 1996;47(6):1567-71.
1996: Petroff O A; Behar K L; Mattson R H; Rothman D L
Human brain gamma-aminobutyric acid levels and seizure control following initiation of vigabatrin therapy.
Journal of neurochemistry 1996;67(6):2399-404.
1996: Velho G; Petersen K F; Perseghin G; Hwang J H; Rothman D L; Pueyo M E; Cline G W; Froguel P; Shulman G I
Impaired hepatic glycogen synthesis in glucokinase-deficient (MODY-2) subjects.
The Journal of clinical investigation 1996;98(8):1755-61.
1996: Perseghin G; Price T B; Petersen K F; Roden M; Cline G W; Gerow K; Rothman D L; Shulman G I
Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects.
The New England journal of medicine 1996;335(18):1357-62.
1996: Manor D; Rothman D L; Mason G F; Hyder F; Petroff O A; Behar K L
The rate of turnover of cortical GABA from [1-13C]glucose is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA).
Neurochemical research 1996;21(9):1031-41.
1996: Blamire A M; Rothman D L; Nixon T
Dynamic shim updating: a new approach towards optimized whole brain shimming.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1996;36(1):159-65.
1996: Hyder F; Chase J R; Behar K L; Mason G F; Siddeek M; Rothman D L; Shulman R G
Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with 1H[13C]NMR.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7612-7.
1996: Shulman R G; Rothman D L
Enzymatic phosphorylation of muscle glycogen synthase: a mechanism for maintenance of metabolic homeostasis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7491-5.
1996: Petersen K F; West A B; Reuben A; Rothman D L; Shulman G I
Noninvasive assessment of hepatic triglyceride content in humans with 13C nuclear magnetic resonance spectroscopy.
Hepatology (Baltimore, Md.) 1996;24(1):114-7.
1996: Roden M; Price T B; Perseghin G; Petersen K F; Rothman D L; Cline G W; Shulman G I
Mechanism of free fatty acid-induced insulin resistance in humans.
The Journal of clinical investigation 1996;97(12):2859-65.
1996: Hwang J H; Graham G D; Behar K L; Alger J R; Prichard J W; Rothman D L
Short echo time proton magnetic resonance spectroscopic imaging of macromolecule and metabolite signal intensities in the human brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1996;35(5):633-9.
1996: Price T B; Perseghin G; Duleba A; Chen W; Chase J; Rothman D L; Shulman R G; Shulman G I
NMR studies of muscle glycogen synthesis in insulin-resistant offspring of parents with non-insulin-dependent diabetes mellitus immediately after glycogen-depleting exercise.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5329-34.
1996: Petroff O A; Rothman D L; Behar K L; Mattson R H
Human brain GABA levels rise after initiation of vigabatrin therapy but fail to rise further with increasing dose.
Neurology 1996;46(5):1459-63.
1996: Gruetter R; Novotny E J; Boulware S D; Rothman D L; Shulman R G
1H NMR studies of glucose transport in the human brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(3):427-38.
1996: Roden M; Perseghin G; Petersen K F; Hwang J H; Cline G W; Gerow K; Rothman D L; Shulman G I
The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans.
The Journal of clinical investigation 1996;97(3):642-8.
1996: Petersen K F; Price T; Cline G W; Rothman D L; Shulman G I
Contribution of net hepatic glycogenolysis to glucose production during the early postprandial period.
The American journal of physiology 1996;270(1 Pt 1):E186-91.
1996: Petroff O A; Rothman D L; Behar K L; Lamoureux D; Mattson R H
The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy.
Annals of neurology 1996;39(1):95-9.
1996: Taylor R; Magnusson I; Rothman D L; Cline G W; Caumo A; Cobelli C; Shulman G I
Direct assessment of liver glycogen storage by 13C nuclear magnetic resonance spectroscopy and regulation of glucose homeostasis after a mixed meal in normal subjects.
The Journal of clinical investigation 1996;97(1):126-32.
1996: Shulman R G; Rothman D L; Price T B
Nuclear magnetic resonance studies of muscle and applications to exercise and diabetes.
Diabetes 1996;45 Suppl 1():S93-8.
1995: Shulman R G; Bloch G; Rothman D L
In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(19):8535-42.
1995: Petroff O A; Rothman D L; Behar K L; Mattson R H
Initial observations on effect of vigabatrin on in vivo 1H spectroscopic measurements of gamma-aminobutyric acid, glutamate, and glutamine in human brain.
Epilepsia 1995;36(5):457-64.
1995: Hwang J H; Perseghin G; Rothman D L; Cline G W; Magnusson I; Petersen K F; Shulman G I
Impaired net hepatic glycogen synthesis in insulin-dependent diabetic subjects during mixed meal ingestion. A 13C nuclear magnetic resonance spectroscopy study.
The Journal of clinical investigation 1995;95(2):783-7.
1995: Magnusson I; Rothman D L; Gerard D P; Katz L D; Shulman G I
Contribution of hepatic glycogenolysis to glucose production in humans in response to a physiological increase in plasma glucagon concentration.
Diabetes 1995;44(2):185-9.
1995: Novotny E J; Avison M J; Herschkowitz N; Petroff O A; Prichard J W; Seashore M R; Rothman D L
In vivo measurement of phenylalanine in human brain by proton nuclear magnetic resonance spectroscopy.
Pediatric research 1995;37(2):244-9.
1995: Mason G F; Gruetter R; Rothman D L; Behar K L; Shulman R G; Novotny E J
Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(1):12-25.
1995: Hyder F; Rothman D L; Blamire A M
Image reconstruction of sequentially sampled echo-planar data.
Magnetic resonance imaging 1995;13(1):97-103.
1994: Cline G W; Rothman D L; Magnusson I; Katz L D; Shulman G I
13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus.
The Journal of clinical investigation 1994;94(6):2369-76.
1994: Gruetter R; Novotny E J; Boulware S D; Mason G F; Rothman D L; Shulman G I; Prichard J W; Shulman R G
Localized 13C NMR spectroscopy in the human brain of amino acid labeling from D-[1-13C]glucose.
Journal of neurochemistry 1994;63(4):1377-85.
1994: Behar K L; Rothman D L; Spencer D D; Petroff O A
Analysis of macromolecule resonances in 1H NMR spectra of human brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1994;32(3):294-302.
1994: Price T B; Taylor R; Mason G F; Rothman D L; Shulman G I; Shulman R G
Turnover of human muscle glycogen with low-intensity exercise.
Medicine and science in sports and exercise 1994;26(8):983-91.
1994: Gruetter R; Magnusson I; Rothman D L; Avison M J; Shulman R G; Shulman G I
Validation of 13C NMR measurements of liver glycogen in vivo.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1994;31(6):583-8.
1994: Magnusson I; Rothman D L; Jucker B; Cline G W; Shulman R G; Shulman G I
Liver glycogen turnover in fed and fasted humans.
The American journal of physiology 1994;266(5 Pt 1):E796-803.
1994: Price T B; Rothman D L; Taylor R; Avison M J; Shulman G I; Shulman R G
Human muscle glycogen resynthesis after exercise: insulin-dependent and -independent phases.
Journal of applied physiology (Bethesda, Md. : 1985) 1994;76(1):104-11.
1994: Blamire A M; Graham G D; Rothman D L; Prichard J W
Proton spectroscopy of human stroke: assessment of transverse relaxation times and partial volume effects in single volume steam MRS.
Magnetic resonance imaging 1994;12(8):1227-35.
1993: Graham G D; Blamire A M; Rothman D L; Brass L M; Fayad P B; Petroff O A; Prichard J W
Early temporal variation of cerebral metabolites after human stroke. A proton magnetic resonance spectroscopy study.
Stroke; a journal of cerebral circulation 1993;24(12):1891-6.
1993: Chen W; Novotny E J; Zhu X H; Rothman D L; Shulman R G
Localized 1H NMR measurement of glucose consumption in the human brain during visual stimulation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):9896-900.
1993: Rothman D L; Petroff O A; Behar K L; Mattson R H
Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5662-6.
1993: McCarthy G; Blamire A M; Rothman D L; Gruetter R; Shulman R G
Echo-planar magnetic resonance imaging studies of frontal cortex activation during word generation in humans.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):4952-6.
1993: Shulman R G; Blamire A M; Rothman D L; McCarthy G
Nuclear magnetic resonance imaging and spectroscopy of human brain function.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3127-33.
1993: Gruetter R; Novotny E J; Boulware S D; Rothman D L; Mason G F; Shulman G I; Tamborlane W V; Shulman R G
Non-invasive measurements of the cerebral steady-state glucose concentration and transport in humans by 13C nuclear magnetic resonance.
Advances in experimental medicine and biology 1993;331():35-40.
1992: Petroff O A; Novotny E J; Avison M; Rothman D L; Alger J R; Ogino T; Shulman G I; Prichard J W
Cerebral lactate turnover after electroshock: in vivo measurements by 1H/13C magnetic resonance spectroscopy.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(6):1022-9.
1992: Rothman D L; Novotny E J; Shulman G I; Howseman A M; Petroff O A; Mason G; Nixon T; Hanstock C C; Prichard J W; Shulman R G
1H-[13C] NMR measurements of [4-13C]glutamate turnover in human brain.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(20):9603-6.
1992: Magnusson I; Rothman D L; Katz L D; Shulman R G; Shulman G I
Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study.
The Journal of clinical investigation 1992;90(4):1323-7.
1992: Gruetter R; Rothman D L; Novotny E J; Shulman G I; Prichard J W; Shulman R G
Detection and assignment of the glucose signal in 1H NMR difference spectra of the human brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1992;27(1):183-8.
1992: Taylor R; Price T B; Rothman D L; Shulman R G; Shulman G I
Validation of 13C NMR measurement of human skeletal muscle glycogen by direct biochemical assay of needle biopsy samples.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1992;27(1):13-20.
1992: Petroff O A; Graham G D; Blamire A M; al-Rayess M; Rothman D L; Fayad P B; Brass L M; Shulman R G; Prichard J W
Spectroscopic imaging of stroke in humans: histopathology correlates of spectral changes.
Neurology 1992;42(7):1349-54.
1992: Gruetter R; Rothman D L; Novotny E J; Shulman R G
Localized 13C NMR spectroscopy of myo-inositol in the human brain in vivo.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1992;25(1):204-10.
1992: Mason G F; Behar K L; Rothman D L; Shulman R G
NMR determination of intracerebral glucose concentration and transport kinetics in rat brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(3):448-55.
1992: Rothman D L; Hanstock C C; Petroff O A; Novotny E J; Prichard J W; Shulman R G
Localized 1H NMR spectra of glutamate in the human brain.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1992;25(1):94-106.
1992: Mason G F; Rothman D L; Behar K L; Shulman R G
NMR determination of the TCA cycle rate and alpha-ketoglutarate/glutamate exchange rate in rat brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1992;12(3):434-47.
1992: Rothman D L; Shulman R G; Shulman G I
31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus.
The Journal of clinical investigation 1992;89(4):1069-75.
1992: Graham G D; Blamire A M; Howseman A M; Rothman D L; Fayad P B; Brass L M; Petroff O A; Shulman R G; Prichard J W
Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patients.
Stroke; a journal of cerebral circulation 1992;23(3):333-40.
1992: Gruetter R; Novotny E J; Boulware S D; Rothman D L; Mason G F; Shulman G I; Shulman R G; Tamborlane W V
Direct measurement of brain glucose concentrations in humans by 13C NMR spectroscopy.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(3):1109-12.
1991: Rothman D L; Magnusson I; Katz L D; Shulman R G; Shulman G I
Quantitation of hepatic glycogenolysis and gluconeogenesis in fasting humans with 13C NMR.
Science (New York, N.Y.) 1991;254(5031):573-6.
1991: Rothman D L; Howseman A M; Graham G D; Petroff O A; Lantos G; Fayad P B; Brass L M; Shulman G I; Shulman R G; Prichard J W
Localized proton NMR observation of [3-13C]lactate in stroke after [1-13C]glucose infusion.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1991;21(2):302-7.
1991: Avison M J; Rothman D L; Nixon T W; Long W S; Siegel N J
1H NMR study of renal trimethylamine responses to dehydration and acute volume loading in man.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):6053-7.
1991: Pan J W; Hamm J R; Hetherington H P; Rothman D L; Shulman R G
Correlation of lactate and pH in human skeletal muscle after exercise by 1H NMR.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1991;20(1):57-65.
1991: Price T B; Rothman D L; Avison M J; Buonamico P; Shulman R G
13C-NMR measurements of muscle glycogen during low-intensity exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;70(4):1836-44.
1991: Shulman R G; Rothman D L; Behar K L; Prichard J W
High resolution NMR studies of cerebral glucose metabolism in rats and humans.
Advances in experimental medicine and biology 1991;291():5-8.
1990: Novotny E J; Ogino T; Rothman D L; Petroff O A; Prichard J W; Shulman R G
Direct carbon versus proton heteronuclear editing of 2-13C ethanol in rabbit brain in vivo: a sensitivity comparison.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1990;16(3):431-43.
1990: Zang L H; Laughlin M R; Rothman D L; Shulman R G
13C NMR relaxation times of hepatic glycogen in vitro and in vivo.
Biochemistry 1990;29(29):6815-20.
1990: Avison M J; Herschkowitz N; Novotny E J; Petroff O A; Rothman D L; Colombo J P; Bachmann C; Shulman R G; Prichard J W
Proton NMR observation of phenylalanine and an aromatic metabolite in the rabbit brain in vivo.
Pediatric research 1990;27(6):566-70.
1990: Zang L H; Rothman D L; Shulman R G
1H NMR visibility of mammalian glycogen in solution.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(5):1678-80.
1990: Hanstock C C; Rothman D L; Shulman R G; Novotny E J; Petroff O A; Prichard J W
Measurement of ethanol in the human brain using NMR spectroscopy.
Journal of studies on alcohol 1990;51(2):104-7.
1990: Shulman G I; Rothman D L; Jue T; Stein P; DeFronzo R A; Shulman R G
Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy.
The New England journal of medicine 1990;322(4):223-8.
1989: Behar K L; Rothman D L; Hossmann K A
NMR spectroscopic investigation of the recovery of energy and acid-base homeostasis in the cat brain after prolonged ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1989;9(5):655-65.
1989: Rossetti L; Rothman D L; DeFronzo R A; Shulman G I
Effect of dietary protein on in vivo insulin action and liver glycogen repletion.
The American journal of physiology 1989;257(2 Pt 1):E212-9.
1989: Jue T; Rothman D L; Shulman G I; Tavitian B A; DeFronzo R A; Shulman R G
Direct observation of glycogen synthesis in human muscle with 13C NMR.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4489-91.
1989: Jue T; Rothman D L; Tavitian B A; Shulman R G
Natural-abundance 13C NMR study of glycogen repletion in human liver and muscle.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(5):1439-42.
1988: Pan J W; Hamm J R; Rothman D L; Shulman R G
Intracellular pH in human skeletal muscle by 1H NMR.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(21):7836-9.
1988: Shulman G I; Rothman D L; Chung Y; Rossetti L; Petit W A; Barrett E J; Shulman R G
13C NMR studies of glycogen turnover in the perfused rat liver.
The Journal of biological chemistry 1988;263(11):5027-9.
1988: Avison M J; Rothman D L; Nadel E; Shulman R G
Detection of human muscle glycogen by natural abundance 13C NMR.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(5):1634-6.
1988: Hanstock C C; Rothman D L; Prichard J W; Jue T; Shulman R G
Spatially localized 1H NMR spectra of metabolites in the human brain.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(6):1821-5.
1988: Jue T; Rothman D L; Lohman J A; Hughes E W; Hanstock C C; Shulman R G
Surface coil localization of 31P NMR signals from orthotopic human kidney and liver.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(4):971-4.

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