James Rothman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Chemicals & Drugs

Physiology

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Giraudo Claudio G; Garcia-Diaz Alejandro; Eng William S; Chen Yuhang; Hendrickson Wayne A; Melia Thomas J; Rothman James E
Alternative zippering as an on-off switch for SNARE-mediated fusion.
Paumet Fabienne; Wesolowski Jordan; Garcia-Diaz Alejandro; Delevoye Cedric; Aulner Nathalie; Shuman Howard A; Subtil Agathe; Rothman James E
Intracellular bacteria encode inhibitory SNARE-like proteins.
Giraudo Claudio G; Garcia-Diaz Alejandro; Eng William S; Yamamoto Ai; Melia Thomas J; Rothman James E
Distinct domains of complexins bind SNARE complexes and clamp fusion in vitro.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of James Rothman (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Giraudo Claudio G; Garcia-Diaz Alejandro; Eng William S; Chen Yuhang; Hendrickson Wayne A; Melia Thomas J; Rothman James E
Alternative zippering as an on-off switch for SNARE-mediated fusion.
Science (New York, N.Y.) 2009;323(5913):512-6.
2009: Paumet Fabienne; Wesolowski Jordan; Garcia-Diaz Alejandro; Delevoye Cedric; Aulner Nathalie; Shuman Howard A; Subtil Agathe; Rothman James E
Intracellular bacteria encode inhibitory SNARE-like proteins.
PloS one 2009;4(10):e7375.
2008: Giraudo Claudio G; Garcia-Diaz Alejandro; Eng William S; Yamamoto Ai; Melia Thomas J; Rothman James E
Distinct domains of complexins bind SNARE complexes and clamp fusion in vitro.
The Journal of biological chemistry 2008;283(30):21211-9.
2008: Tareste David; Shen Jingshi; Melia Thomas J; Rothman James E
SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2380-5.
2007: Li Feng; Pincet Frédéric; Perez Eric; Eng William S; Melia Thomas J; Rothman James E; Tareste David
Energetics and dynamics of SNAREpin folding across lipid bilayers.
Nature structural & molecular biology 2007;14(10):890-6.
2007: Shen Jingshi; Tareste David C; Paumet Fabienne; Rothman James E; Melia Thomas J
Selective activation of cognate SNAREpins by Sec1/Munc18 proteins.
Cell 2007;128(1):183-95.
2006: Melia Thomas J; You Daoqi; Tareste David C; Rothman James E
Lipidic antagonists to SNARE-mediated fusion.
The Journal of biological chemistry 2006;281(40):29597-605.
2006: Giraudo Claudio G; Eng William S; Melia Thomas J; Rothman James E
A clamping mechanism involved in SNARE-dependent exocytosis.
Science (New York, N.Y.) 2006;313(5787):676-80.
2006: Antinozzi Peter A; Garcia-Diaz Alejandro; Hu Chuan; Rothman James E
Functional mapping of disease susceptibility loci using cell biology.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3698-703.
2006: Yamamoto Ai; Cremona M Laura; Rothman James E
Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway.
The Journal of cell biology 2006;172(5):719-31.
2006: Mayer Thomas; Jagla Bernd; Wyler Michael R; Kelly Peter D; Aulner Nathalie; Beard Matthew; Barger Geoffrey; Többen Udo; Smith Deborah H; Brandén Lars; Rothman James E
Cell-based assays using primary endothelial cells to study multiple steps in inflammation.
Methods in enzymology 2006;414():266-83.
2005: Cosson Pierre; Ravazzola Mariella; Varlamov Oleg; Söllner Thomas H; Di Liberto Maurizio; Volchuk Allen; Rothman James E; Orci Lelio
Dynamic transport of SNARE proteins in the Golgi apparatus.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14647-52.
2005: Giraudo Claudio G; Hu Chuan; You Daoqi; Slovic Avram M; Mosharov Eugene V; Sulzer David; Melia Thomas J; Rothman James E
SNAREs can promote complete fusion and hemifusion as alternative outcomes.
The Journal of cell biology 2005;170(2):249-60.
2005: Jagla Bernd; Aulner Nathalie; Kelly Peter D; Song Da; Volchuk Allen; Zatorski Andrzej; Shum David; Mayer Thomas; De Angelis Dino A; Ouerfelli Ouathek; Rutishauser Urs; Rothman James E
Sequence characteristics of functional siRNAs.
RNA (New York, N.Y.) 2005;11(6):864-72.
2005: Paumet Fabienne; Rahimian Vahid; Di Liberto Maurizio; Rothman James E
Concerted auto-regulation in yeast endosomal t-SNAREs.
The Journal of biological chemistry 2005;280(22):21137-43.
2005: Becker Thalia; Volchuk Allen; Rothman James E
Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):4022-6.
2004: Fix Marina; Melia Thomas J; Jaiswal Jyoti K; Rappoport Joshua Z; You Daoqi; Söllner Thomas H; Rothman James E; Simon Sanford M
Imaging single membrane fusion events mediated by SNARE proteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7311-6.
2004: Fukasawa Masayoshi; Varlamov Oleg; Eng William S; Söllner Thomas H; Rothman James E
Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4815-20.
2004: Volchuk Allen; Ravazzola Mariella; Perrelet Alain; Eng William S; Di Liberto Maurizio; Varlamov Oleg; Fukasawa Masayoshi; Engel Thomas; Söllner Thomas H; Rothman James E; Orci Lelio
Countercurrent distribution of two distinct SNARE complexes mediating transport within the Golgi stack.
Molecular biology of the cell 2004;15(4):1506-18.
2004: Paumet Fabienne; Rahimian Vahid; Rothman James E
The specificity of SNARE-dependent fusion is encoded in the SNARE motif.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(10):3376-80.
2004: Varlamov Oleg; Volchuk Allen; Rahimian Vahid; Doege Claudia A; Paumet Fabienne; Eng William S; Arango Nancy; Parlati Francesco; Ravazzola Mariella; Orci Lelio; Söllner Thomas H; Rothman James E
i-SNAREs: inhibitory SNAREs that fine-tune the specificity of membrane fusion.
The Journal of cell biology 2004;164(1):79-88.
2003: Burri Lena; Varlamov Oleg; Doege Claudia A; Hofmann Kay; Beilharz Traude; Rothman James E; Söllner Thomas H; Lithgow Trevor
A SNARE required for retrograde transport to the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9873-7.
2003: Hu Chuan; Ahmed Mahiuddin; Melia Thomas J; Söllner Thomas H; Mayer Thomas; Rothman James E
Fusion of cells by flipped SNAREs.
Science (New York, N.Y.) 2003;300(5626):1745-9.
2002: Rothman James E
Lasker Basic Medical Research Award. The machinery and principles of vesicle transport in the cell.
Nature medicine 2002;8(10):1059-62.
2002: Cosson Pierre; Amherdt Mylene; Rothman James E; Orci Lelio
A resident Golgi protein is excluded from peri-Golgi vesicles in NRK cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):12831-4.
2002: Melia Thomas J; Weber Thomas; McNew James A; Fisher Lillian E; Johnston Robert J; Parlati Frank; Mahal Lara K; Sollner Thomas H; Rothman James E
Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins.
The Journal of cell biology 2002;158(5):929-40.
2002: Parlati Francesco; Varlamov Oleg; Paz Keren; McNew James A; Hurtado David; Söllner Thomas H; Rothman James E
Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5424-9.
2001: Paumet F; Brügger B; Parlati F; McNew J A; Söllner T H; Rothman J E
A t-SNARE of the endocytic pathway must be activated for fusion.
The Journal of cell biology 2001;155(6):961-8.
2001: Wimmer C; Hohl T M; Hughes C A; Müller S A; Söllner T H; Engel A; Rothman J E
Molecular mass, stoichiometry, and assembly of 20 S particles.
The Journal of biological chemistry 2001;276(31):29091-7.
2000: Fukuda R; McNew J A; Weber T; Parlati F; Engel T; Nickel W; Rothman J E; Söllner T H
Functional architecture of an intracellular membrane t-SNARE.
Nature 2000;407(6801):198-202.
2000: Parlati F; McNew J A; Fukuda R; Miller R; Söllner T H; Rothman J E
Topological restriction of SNARE-dependent membrane fusion.
Nature 2000;407(6801):194-8.
2000: McNew J A; Parlati F; Fukuda R; Johnston R J; Paz K; Paumet F; Söllner T H; Rothman J E
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins.
Nature 2000;407(6801):153-9.
2000: Orci L; Amherdt M; Ravazzola M; Perrelet A; Rothman J E
Exclusion of golgi residents from transport vesicles budding from Golgi cisternae in intact cells.
The Journal of cell biology 2000;150(6):1263-70.
2000: Orci L; Ravazzola M; Volchuk A; Engel T; Gmachl M; Amherdt M; Perrelet A; Sollner T H; Rothman J E
Anterograde flow of cargo across the golgi stack potentially mediated via bidirectional "percolating" COPI vesicles.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(19):10400-5.
2000: Volchuk A; Amherdt M; Ravazzola M; Brügger B; Rivera V M; Clackson T; Perrelet A; Söllner T H; Rothman J E; Orci L
Megavesicles implicated in the rapid transport of intracisternal aggregates across the Golgi stack.
Cell 2000;102(3):335-48.
2000: McNew J A; Weber T; Parlati F; Johnston R J; Melia T J; Söllner T H; Rothman J E
Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors.
The Journal of cell biology 2000;150(1):105-17.
2000: Weber T; Parlati F; McNew J A; Johnston R J; Westermann B; Söllner T H; Rothman J E
SNAREpins are functionally resistant to disruption by NSF and alphaSNAP.
The Journal of cell biology 2000;149(5):1063-72.
2000: Moroi Y; Mayhew M; Trcka J; Hoe M H; Takechi Y; Hartl F U; Rothman J E; Houghton A N
Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3485-90.
2000: Brügger B; Nickel W; Weber T; Parlati F; McNew J A; Rothman J E; Söllner T
Putative fusogenic activity of NSF is restricted to a lipid mixture whose coalescence is also triggered by other factors.
The EMBO journal 2000;19(6):1272-8.
2000: Rivera V M; Wang X; Wardwell S; Courage N L; Volchuk A; Keenan T; Holt D A; Gilman M; Orci L; Cerasoli F; Rothman J E; Clackson T
Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum.
Science (New York, N.Y.) 2000;287(5454):826-30.
1999: Nickel W; Weber T; McNew J A; Parlati F; Söllner T H; Rothman J E
Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12571-6.
1999: Parlati F; Weber T; McNew J A; Westermann B; Söllner T H; Rothman J E
Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12565-70.
1999: McNew J A; Weber T; Engelman D M; Söllner T H; Rothman J E
The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion.
Molecular cell 1999;4(3):415-21.
1999: Bremser M; Nickel W; Schweikert M; Ravazzola M; Amherdt M; Hughes C A; Söllner T H; Rothman J E; Wieland F T
Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors.
Cell 1999;96(4):495-506.
1998: Hohl T M; Parlati F; Wimmer C; Rothman J E; Söllner T H; Engelhardt H
Arrangement of subunits in 20 S particles consisting of NSF, SNAPs, and SNARE complexes.
Molecular cell 1998;2(5):539-48.
1998: Stamnes M; Schiavo G; Stenbeck G; Söllner T H; Rothman J E
ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13676-80.
1998: De Angelis D A; Miesenböck G; Zemelman B V; Rothman J E
PRIM: proximity imaging of green fluorescent protein-tagged polypeptides.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12312-6.
1998: Miesenböck G; De Angelis D A; Rothman J E
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins.
Nature 1998;394(6689):192-5.
1998: Weber T; Zemelman B V; McNew J A; Westermann B; Gmachl M; Parlati F; Söllner T H; Rothman J E
SNAREpins: minimal machinery for membrane fusion.
Cell 1998;92(6):759-72.
1998: Orci L; Perrelet A; Rothman J E
Vesicles on strings: morphological evidence for processive transport within the Golgi stack.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2279-83.
1997: Fiedler K; Rothman J E
Sorting determinants in the transmembrane domain of p24 proteins.
The Journal of biological chemistry 1997;272(40):24739-42.
1997: Orci L; Stamnes M; Ravazzola M; Amherdt M; Perrelet A; Söllner T H; Rothman J E
Bidirectional transport by distinct populations of COPI-coated vesicles.
Cell 1997;90(2):335-49.
1997: McNew J A; Sogaard M; Lampen N M; Machida S; Ye R R; Lacomis L; Tempst P; Rothman J E; Söllner T H
Ykt6p, a prenylated SNARE essential for endoplasmic reticulum-Golgi transport.
The Journal of biological chemistry 1997;272(28):17776-83.
1997: Paek I; Orci L; Ravazzola M; Erdjument-Bromage H; Amherdt M; Tempst P; Söllner T H; Rothman J E
ERS-24, a mammalian v-SNARE implicated in vesicle traffic between the ER and the Golgi.
The Journal of cell biology 1997;137(5):1017-28.
1997: Rothman J E; Söllner T H
Throttles and dampers: controlling the engine of membrane fusion.
Science (New York, N.Y.) 1997;276(5316):1212-3.
1997: Miesenböck G; Rothman J E
Patterns of synaptic activity in neural networks recorded by light emission from synaptolucins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3402-7.
1997: Schiavo G; Stenbeck G; Rothman J E; Söllner T H
Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(3):997-1001.
1996: Söllner T H; Rothman J E
Molecular machinery mediating vesicle budding, docking and fusion.
Experientia 1996;52(12):1021-5.
1996: Schiavo G; Gu Q M; Prestwich G D; Söllner T H; Rothman J E
Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13327-32.
1996: Söllner T H; Rothman J E
Molecular machinery mediating vesicle budding, docking and fusion.
Cell structure and function 1996;21(5):407-12.
1996: Fiedler K; Veit M; Stamnes M A; Rothman J E
Bimodal interaction of coatomer with the p24 family of putative cargo receptors.
Science (New York, N.Y.) 1996;273(5280):1396-9.
1996: Nagahama M; Orci L; Ravazzola M; Amherdt M; Lacomis L; Tempst P; Rothman J E; Söllner T H
A v-SNARE implicated in intra-Golgi transport.
The Journal of cell biology 1996;133(3):507-16.
1996: Veit M; Söllner T H; Rothman J E
Multiple palmitoylation of synaptotagmin and the t-SNARE SNAP-25.
FEBS letters 1996;385(1-2):119-23.
1996: Rothman J E; Wieland F T
Protein sorting by transport vesicles.
Science (New York, N.Y.) 1996;272(5259):227-34.
1996: Rothman J E
The protein machinery of vesicle budding and fusion.
Protein science : a publication of the Protein Society 1996;5(2):185-94.
1995: Schiavo G; Gmachl M J; Stenbeck G; Söllner T H; Rothman J E
A possible docking and fusion particle for synaptic transmission.
Nature 1995;378(6558):733-6.
1995: Stamnes M A; Craighead M W; Hoe M H; Lampen N; Geromanos S; Tempst P; Rothman J E
An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):8011-5.
1995: Miesenböck G; Rothman J E
The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack.
The Journal of cell biology 1995;129(2):309-19.
1994: Orci L; Perrelet A; Ravazzola M; Amherdt M; Rothman J E; Schekman R
Coatomer-rich endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):11924-8.
1994: Rothman J E
Mechanisms of intracellular protein transport.
Nature 1994;372(6501):55-63.
1994: Søgaard M; Tani K; Ye R R; Geromanos S; Tempst P; Kirchhausen T; Rothman J E; Söllner T
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles.
Cell 1994;78(6):937-48.
1994: Whiteheart S W; Rossnagel K; Buhrow S A; Brunner M; Jaenicke R; Rothman J E
N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion.
The Journal of cell biology 1994;126(4):945-54.
1994: Söllner T; Rothman J E
Neurotransmission: harnessing fusion machinery at the synapse.
Trends in neurosciences 1994;17(8):344-8.
1994: Kuge O; Dascher C; Orci L; Rowe T; Amherdt M; Plutner H; Ravazzola M; Tanigawa G; Rothman J E; Balch W E
Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments.
The Journal of cell biology 1994;125(1):51-65.
1994: Hara-Kuge S; Kuge O; Orci L; Amherdt M; Ravazzola M; Wieland F T; Rothman J E
En bloc incorporation of coatomer subunits during the assembly of COP-coated vesicles.
The Journal of cell biology 1994;124(6):883-92.
1994: Rothman J E; Warren G
Implications of the SNARE hypothesis for intracellular membrane topology and dynamics.
Current biology : CB 1994;4(3):220-33.
1994: Elazar Z; Orci L; Ostermann J; Amherdt M; Tanigawa G; Rothman J E
ADP-ribosylation factor and coatomer couple fusion to vesicle budding.
The Journal of cell biology 1994;124(4):415-24.
1994: Elazar Z; Mayer T; Rothman J E
Removal of Rab GTP-binding proteins from Golgi membranes by GDP dissociation inhibitor inhibits inter-cisternal transport in the Golgi stacks.
The Journal of biological chemistry 1994;269(2):794-7.
1993: Kuge O; Hara-Kuge S; Orci L; Ravazzola M; Amherdt M; Tanigawa G; Wieland F T; Rothman J E
zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly.
The Journal of cell biology 1993;123(6 Pt 2):1727-34.
1993: Tanigawa G; Orci L; Amherdt M; Ravazzola M; Helms J B; Rothman J E
Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles.
The Journal of cell biology 1993;123(6 Pt 1):1365-71.
1993: Ostermann J; Orci L; Tani K; Amherdt M; Ravazzola M; Elazar Z; Rothman J E
Stepwise assembly of functionally active transport vesicles.
Cell 1993;75(5):1015-25.
1993: Orci L; Perrelet A; Ravazzola M; Wieland F T; Schekman R; Rothman J E
"BFA bodies": a subcompartment of the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11089-93.
1993: Söllner T; Bennett M K; Whiteheart S W; Scheller R H; Rothman J E
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion.
Cell 1993;75(3):409-18.
1993: Orcl L; Palmer D J; Amherdt M; Rothman J E
Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol.
Nature 1993;364(6439):732-4.
1993: Palmer D J; Helms J B; Beckers C J; Orci L; Rothman J E
Binding of coatomer to Golgi membranes requires ADP-ribosylation factor.
The Journal of biological chemistry 1993;268(16):12083-9.
1993: Stamnes M A; Rothman J E
The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein.
Cell 1993;73(5):999-1005.
1993: Helms J B; Palmer D J; Rothman J E
Two distinct populations of ARF bound to Golgi membranes.
The Journal of cell biology 1993;121(4):751-60.
1993: Orci L; Palmer D J; Ravazzola M; Perrelet A; Amherdt M; Rothman J E
Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins.
Nature 1993;362(6421):648-52.
1993: Whiteheart S W; Griff I C; Brunner M; Clary D O; Mayer T; Buhrow S A; Rothman J E
SNAP family of NSF attachment proteins includes a brain-specific isoform.
Nature 1993;362(6418):353-5.
1993: Söllner T; Whiteheart S W; Brunner M; Erdjument-Bromage H; Geromanos S; Tempst P; Rothman J E
SNAP receptors implicated in vesicle targeting and fusion.
Nature 1993;362(6418):318-24.
1993: Tagaya M; Wilson D W; Brunner M; Arango N; Rothman J E
Domain structure of an N-ethylmaleimide-sensitive fusion protein involved in vesicular transport.
The Journal of biological chemistry 1993;268(4):2662-6.
1992: Stenbeck G; Schreiner R; Herrmann D; Auerbach S; Lottspeich F; Rothman J E; Wieland F T
Gamma-COP, a coat subunit of non-clathrin-coated vesicles with homology to Sec21p.
FEBS letters 1992;314(2):195-8.
1992: Helms J B; Rothman J E
Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF.
Nature 1992;360(6402):352-4.
1992: Waters M G; Clary D O; Rothman J E
A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack.
The Journal of cell biology 1992;118(5):1015-26.
1992: Kahn R A; Randazzo P; Serafini T; Weiss O; Rulka C; Clark J; Amherdt M; Roller P; Orci L; Rothman J E
The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport.
The Journal of biological chemistry 1992;267(18):13039-46.
1992: Whiteheart S W; Brunner M; Wilson D W; Wiedmann M; Rothman J E
Soluble N-ethylmaleimide-sensitive fusion attachment proteins (SNAPs) bind to a multi-SNAP receptor complex in Golgi membranes.
The Journal of biological chemistry 1992;267(17):12239-43.
1992: Wilson D W; Whiteheart S W; Wiedmann M; Brunner M; Rothman J E
A multisubunit particle implicated in membrane fusion.
The Journal of cell biology 1992;117(3):531-8.
1992: Rothman J E; Orci L
Molecular dissection of the secretory pathway.
Nature 1992;355(6359):409-15.
1992: Waters M G; Beckers C J; Rothman J E
Purification of coat protomers.
Methods in enzymology 1992;219():331-7.
1991: Flynn G C; Pohl J; Flocco M T; Rothman J E
Peptide-binding specificity of the molecular chaperone BiP.
Nature 1991;353(6346):726-30.
1991: Serafini T; Orci L; Amherdt M; Brunner M; Kahn R A; Rothman J E
ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein.
Cell 1991;67(2):239-53.
1991: Wilson D W; Whiteheart S W; Orci L; Rothman J E
Intracellular membrane fusion.
Trends in biochemical sciences 1991;16(9):334-7.
1991: Waters M G; Griff I C; Rothman J E
Proteins involved in vesicular transport and membrane fusion.
Current opinion in cell biology 1991;3(4):615-20.
1991: Orci L; Tagaya M; Amherdt M; Perrelet A; Donaldson J G; Lippincott-Schwartz J; Klausner R D; Rothman J E
Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae.
Cell 1991;64(6):1183-95.
1991: Rothman J E
Enzymology of intracellular membrane fusion.
Klinische Wochenschrift 1991;69(3):98-104.
1991: Waters M G; Serafini T; Rothman J E
'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles.
Nature 1991;349(6306):248-51.
1991: Serafini T; Stenbeck G; Brecht A; Lottspeich F; Orci L; Rothman J E; Wieland F T
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin.
Nature 1991;349(6306):215-20.
1990: Helms J B; Karrenbauer A; Wirtz K W; Rothman J E; Wieland F T
Reconstitution of steps in the constitutive secretory pathway in permeabilized cells. Secretion of glycosylated tripeptide and truncated sphingomyelin.
The Journal of biological chemistry 1990;265(32):20027-32.
1990: Karrenbauer A; Jeckel D; Just W; Birk R; Schmidt R R; Rothman J E; Wieland F T
The rate of bulk flow from the Golgi to the plasma membrane.
Cell 1990;63(2):259-67.
1990: Clary D O; Rothman J E
Purification of three related peripheral membrane proteins needed for vesicular transport.
The Journal of biological chemistry 1990;265(17):10109-17.
1990: Clary D O; Griff I C; Rothman J E
SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast.
Cell 1990;61(4):709-21.
1990: Pfanner N; Glick B S; Arden S R; Rothman J E
Fatty acylation promotes fusion of transport vesicles with Golgi cisternae.
The Journal of cell biology 1990;110(4):955-61.
1989: Rothman J E
Polypeptide chain binding proteins: catalysts of protein folding and related processes in cells.
Cell 1989;59(4):591-601.
1989: Pfanner N; Orci L; Glick B S; Amherdt M; Arden S R; Malhotra V; Rothman J E
Fatty acyl-coenzyme A is required for budding of transport vesicles from Golgi cisternae.
Cell 1989;59(1):95-102.
1989: Flynn G C; Chappell T G; Rothman J E
Peptide binding and release by proteins implicated as catalysts of protein assembly.
Science (New York, N.Y.) 1989;245(4916):385-90.
1989: Malhotra V; Serafini T; Orci L; Shepherd J C; Rothman J E
Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack.
Cell 1989;58(2):329-36.
1989: Wilson D W; Wilcox C A; Flynn G C; Chen E; Kuang W J; Henzel W J; Block M R; Ullrich A; Rothman J E
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast.
Nature 1989;339(6223):355-9.
1989: Beckers C J; Block M R; Glick B S; Rothman J E; Balch W E
Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein.
Nature 1989;339(6223):397-8.
1989: Weidman P J; Melançon P; Block M R; Rothman J E
Binding of an N-ethylmaleimide-sensitive fusion protein to Golgi membranes requires both a soluble protein(s) and an integral membrane receptor.
The Journal of cell biology 1989;108(5):1589-96.
1989: Orci L; Malhotra V; Amherdt M; Serafini T; Rothman J E
Dissection of a single round of vesicular transport: sequential intermediates for intercisternal movement in the Golgi stack.
Cell 1989;56(3):357-68.
1989: Melançon P; Glick B S; Malhotra V; Weidman P J; Serafini T; Orci L; Rothman J E
A role for GTP-binding proteins in vesicular transport through the Golgi complex.
Society of General Physiologists series 1989;44():175-88.
1988: Block M R; Glick B S; Wilcox C A; Wieland F T; Rothman J E
Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(21):7852-6.
1988: Malhotra V; Orci L; Glick B S; Block M R; Rothman J E
Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack.
Cell 1988;54(2):221-7.
1987: Melançon P; Glick B S; Malhotra V; Weidman P J; Serafini T; Gleason M L; Orci L; Rothman J E
Involvement of GTP-binding "G" proteins in transport through the Golgi stack.
Cell 1987;51(6):1053-62.
1987: Wieland F T; Gleason M L; Serafini T A; Rothman J E
The rate of bulk flow from the endoplasmic reticulum to the cell surface.
Cell 1987;50(2):289-300.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

James Rothman

Research Profile (preview)

Anatomy

Chemicals & Drugs

Physiology

Concepts & Ideas

Genes & Molecular Sequences

Living Beings

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of James Rothman (preview)

All Publications