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James Rothman

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Lei Shi; Yong Jian Wang; Kevin Howan; James E Rothman; Qing-Tao Shen; Frédéric Pincet
Preparation and characterization of SNARE-containing nanodiscs and direct study of cargo release through fusion pores.
Erdem Karatekin; James E Rothman
Fusion of single proteoliposomes with planar, cushioned bilayers in microfluidic flow cells.
Lei Shi; Hong-Wei Wang; Jing Wang; Alexander Kiel; Thomas Melia; James E Rothman; Qing-Tao Shen; Frédéric Pincet
SNARE proteins: one to fuse and three to keep the nascent fusion pore open.

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2013: Lei Shi; Yong Jian Wang; Kevin Howan; James E Rothman; Qing-Tao Shen; Frédéric Pincet
Preparation and characterization of SNARE-containing nanodiscs and direct study of cargo release through fusion pores.
Nature protocols 2013;8(5):935-48.
2012: Erdem Karatekin; James E Rothman
Fusion of single proteoliposomes with planar, cushioned bilayers in microfluidic flow cells.
Nature protocols 2012;7(5):903-20.
2012: Lei Shi; Hong-Wei Wang; Jing Wang; Alexander Kiel; Thomas Melia; James E Rothman; Qing-Tao Shen; Frédéric Pincet
SNARE proteins: one to fuse and three to keep the nascent fusion pore open.
Science (New York, N.Y.) 2012;335(6074):1355-9.
2011: Feng Li; Eric Perez; Frédéric Pincet; Claudio G Giraudo; David Tareste; James E Rothman
Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state.
Nature structural & molecular biology 2011;18(8):941-6.
2011: Maria Laura Cremona; Heinrich Matthies; Kelvin Pau; Erica Bowton; Nicole Speed; Brandon J Lute; Monique Anderson; Namita Sen; Sabrina D Robertson; Roxanne A Vaughan; James E Rothman; Aurelio Galli; Jonathan A Javitch; Ai Yamamoto
Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT.
Nature neuroscience 2011;14(4):469-77.
2010: Hong Ji; Jeff Coleman; Rong Yang; Thomas J Melia; James E Rothman; David Tareste
Protein determinants of SNARE-mediated lipid mixing.
Biophysical journal 2010;99(2):553-60.
2009: Claudio G Giraudo; Alejandro Garcia-Diaz; William S Eng; Yuhang Chen; Wayne A Hendrickson; Thomas Melia; James E Rothman
Alternative zippering as an on-off switch for SNARE-mediated fusion.
Science (New York, N.Y.) 2009;323(5913):512-6.
2009: Fabienne Paumet; Jordan Wesolowski; Alejandro Garcia-Diaz; Cedric Delevoye; Nathalie Aulner; Howard A Shuman; Agathe Subtil; James E Rothman
Intracellular bacteria encode inhibitory SNARE-like proteins.
PloS one 2009;4(10):e7375.
2008: Claudio G Giraudo; Alejandro Garcia-Diaz; William S Eng; Ai Yamamoto; Thomas Melia; James E Rothman
Distinct domains of complexins bind SNARE complexes and clamp fusion in vitro.
The Journal of biological chemistry 2008;283(30):21211-9.
2008: David Tareste; Jingshi Shen; Thomas Melia; James E Rothman
SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2380-5.
2007: Feng Li; Frédéric Pincet; Eric Perez; William S Eng; Thomas Melia; James E Rothman; David Tareste
Energetics and dynamics of SNAREpin folding across lipid bilayers.
Nature structural & molecular biology 2007;14(10):890-6.
2007: Jingshi Shen; David C Tareste; Fabienne Paumet; James E Rothman; Thomas Melia
Selective activation of cognate SNAREpins by Sec1/Munc18 proteins.
Cell 2007;128(1):183-95.
2006: Thomas Melia; Daoqi You; David C Tareste; James E Rothman
Lipidic antagonists to SNARE-mediated fusion.
The Journal of biological chemistry 2006;281(40):29597-605.
2006: Claudio G Giraudo; William S Eng; Thomas Melia; James E Rothman
A clamping mechanism involved in SNARE-dependent exocytosis.
Science (New York, N.Y.) 2006;313(5787):676-80.
2006: Peter A Antinozzi; Alejandro Garcia-Diaz; Chuan Hu; James E Rothman
Functional mapping of disease susceptibility loci using cell biology.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3698-703.
2006: Ai Yamamoto; Maria Laura Cremona; James E Rothman
Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway.
The Journal of cell biology 2006;172(5):719-31.
2006: Thomas Mayer; Bernd Jagla; Michael R Wyler; Peter D Kelly; Nathalie Aulner; Matthew Beard; Geoffrey Barger; Udo Többen; Deborah H. Smith; Lars Brandén; James E Rothman
Cell-based assays using primary endothelial cells to study multiple steps in inflammation.
Methods in enzymology 2006;414():266-83.
2005: Pierre Cosson; Mariella Ravazzola; Oleg Varlamov; Thomas H Söllner; Maurizio Di Liberto; Allen Volchuk; James E Rothman; Lelio Orci
Dynamic transport of SNARE proteins in the Golgi apparatus.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14647-52.
2005: Claudio G Giraudo; Chuan Hu; Daoqi You; Avram M Slovic; Eugene V Mosharov; David Sulzer; Thomas Melia; James E Rothman
SNAREs can promote complete fusion and hemifusion as alternative outcomes.
The Journal of cell biology 2005;170(2):249-60.
2005: Fabienne Paumet; Vahid Rahimian; Maurizio Di Liberto; James E Rothman
Concerted auto-regulation in yeast endosomal t-SNAREs.
The Journal of biological chemistry 2005;280(22):21137-43.
2005: Bernd Jagla; Nathalie Aulner; Peter D Kelly; Da Song; Allen Volchuk; Andrzej Zatorski; David Shum; Thomas Mayer; Dino A De Angelis; Ouathek Ouerfelli; Urs Rutishauser; James E Rothman
Sequence characteristics of functional siRNAs.
RNA (New York, N.Y.) 2005;11(6):864-72.
2005: Thalia Becker; Allen Volchuk; James E Rothman
Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):4022-6.
2004: Marina Fix; Thomas Melia; Jyoti K Jaiswal; Joshua Z Rappoport; Daoqi You; Thomas H Söllner; James E Rothman; Sanford M Simon
Imaging single membrane fusion events mediated by SNARE proteins.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7311-6.
2004: Masayoshi Fukasawa; Oleg Varlamov; William S Eng; Thomas H Söllner; James E Rothman
Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4815-20.
2004: Allen Volchuk; Mariella Ravazzola; Alain Perrelet; William S Eng; Maurizio Di Liberto; Oleg Varlamov; Masayoshi Fukasawa; Thomas Engel; Thomas H Söllner; James E Rothman; Lelio Orci
Countercurrent distribution of two distinct SNARE complexes mediating transport within the Golgi stack.
Molecular biology of the cell 2004;15(4):1506-18.
2004: Fabienne Paumet; Vahid Rahimian; James E Rothman
The specificity of SNARE-dependent fusion is encoded in the SNARE motif.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(10):3376-80.
2004: Oleg Varlamov; Allen Volchuk; Vahid Rahimian; Claudia A Doege; Fabienne Paumet; William S Eng; Nancy Arango; Francesco Parlati; Mariella Ravazzola; Lelio Orci; Thomas H Söllner; James E Rothman
i-SNAREs: inhibitory SNAREs that fine-tune the specificity of membrane fusion.
The Journal of cell biology 2004;164(1):79-88.
2003: Lena Burri; Oleg Varlamov; Claudia A Doege; Kay Hofmann; Traude Beilharz; James E Rothman; Thomas H Söllner; Trevor Lithgow
A SNARE required for retrograde transport to the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9873-7.
2003: Chuan Hu; Mahiuddin Ahmed; Thomas Melia; Thomas H Söllner; Thomas Mayer; James E Rothman
Fusion of cells by flipped SNAREs.
Science (New York, N.Y.) 2003;300(5626):1745-9.
2002: James E Rothman
Lasker Basic Medical Research Award. The machinery and principles of vesicle transport in the cell.
Nature medicine 2002;8(10):1059-62.
2002: Pierre Cosson; Mylene Amherdt; James E Rothman; Lelio Orci
A resident Golgi protein is excluded from peri-Golgi vesicles in NRK cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):12831-4.
2002: Thomas Melia; Thomas Weber; James A McNew; Lillian E Fisher; Robert J Johnston; Francesco Parlati; Lara K Mahal; Thomas H Sollner; James E Rothman
Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins.
The Journal of cell biology 2002;158(5):929-40.
2002: Francesco Parlati; Oleg Varlamov; Keren Paz; James A McNew; David Hurtado; Thomas H Söllner; James E Rothman
Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5424-9.
2001: Fabienne Paumet; Britta Brügger; Francesco Parlati; James A McNew; Thomas H Söllner; James E Rothman
A t-SNARE of the endocytic pathway must be activated for fusion.
The Journal of cell biology 2001;155(6):961-8.
2001: C Wimmer; Tobias M Hohl; C A Hughes; Shirley A Müller; Thomas H Söllner; Andreas Engel; James E Rothman
Molecular mass, stoichiometry, and assembly of 20 S particles.
The Journal of biological chemistry 2001;276(31):29091-7.
2000: Lelio Orci; Mylene Amherdt; Mariella Ravazzola; Alain Perrelet; James E Rothman
Exclusion of golgi residents from transport vesicles budding from Golgi cisternae in intact cells.
The Journal of cell biology 2000;150(6):1263-70.
2000: R Fukuda; James A McNew; Thomas Weber; Francesco Parlati; Thomas Engel; Walter Nickel; James E Rothman; Thomas H Söllner
Functional architecture of an intracellular membrane t-SNARE.
Nature 2000;407(6801):198-202.
2000: Francesco Parlati; James A McNew; R Fukuda; R Miller; Thomas H Söllner; James E Rothman
Topological restriction of SNARE-dependent membrane fusion.
Nature 2000;407(6801):194-8.
2000: James A McNew; Francesco Parlati; R Fukuda; Robert J Johnston; Keren Paz; Fabienne Paumet; Thomas H Söllner; James E Rothman
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins.
Nature 2000;407(6801):153-9.
2000: Lelio Orci; Mariella Ravazzola; Allen Volchuk; Thomas Engel; M Gmachl; Mylene Amherdt; Alain Perrelet; T H Sollner; James E Rothman
Anterograde flow of cargo across the golgi stack potentially mediated via bidirectional "percolating" COPI vesicles.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(19):10400-5.
2000: Allen Volchuk; Mylene Amherdt; Mariella Ravazzola; Britta Brügger; Victor M Rivera; Tim Clackson; Alain Perrelet; Thomas H Söllner; James E Rothman; Lelio Orci
Megavesicles implicated in the rapid transport of intracisternal aggregates across the Golgi stack.
Cell 2000;102(3):335-48.
2000: James A McNew; Thomas Weber; Francesco Parlati; Robert J Johnston; Thomas Melia; Thomas H Söllner; James E Rothman
Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors.
The Journal of cell biology 2000;150(1):105-17.
2000: Thomas Weber; Francesco Parlati; James A McNew; Robert J Johnston; B Westermann; Thomas H Söllner; James E Rothman
SNAREpins are functionally resistant to disruption by NSF and alphaSNAP.
The Journal of cell biology 2000;149(5):1063-72.
2000: Yoichi Moroi; M Mayhew; Jiri Trcka; M H Hoe; Y Takechi; F Ulrich Hartl; James E Rothman; Alan N Houghton
Induction of cellular immunity by immunization with novel hybrid peptides complexed to heat shock protein 70.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3485-90.
2000: Britta Brügger; Walter Nickel; Thomas Weber; Francesco Parlati; James A McNew; James E Rothman; Thomas H Söllner
Putative fusogenic activity of NSF is restricted to a lipid mixture whose coalescence is also triggered by other factors.
The EMBO journal 2000;19(6):1272-8.
2000: Victor M Rivera; X Wang; S Wardwell; NL Courage; Allen Volchuk; Terence P Keenan; Dennis A Holt; M Gilman; Lelio Orci; frank cerasoli; James E Rothman; Tim Clackson
Regulation of protein secretion through controlled aggregation in the endoplasmic reticulum.
Science (New York, N.Y.) 2000;287(5454):826-30.
1999: Walter Nickel; Thomas Weber; James A McNew; Francesco Parlati; Thomas H Söllner; James E Rothman
Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12571-6.
1999: Francesco Parlati; Thomas Weber; James A McNew; B Westermann; Thomas H Söllner; James E Rothman
Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12565-70.
1999: James A McNew; Thomas Weber; D M Engelman; Thomas H Söllner; James E Rothman
The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion.
Molecular cell 1999;4(3):415-21.
1999: M Bremser; Walter Nickel; M Schweikert; Mariella Ravazzola; Mylene Amherdt; C A Hughes; Thomas H Söllner; James E Rothman; Felix T Wieland
Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors.
Cell 1999;96(4):495-506.
1998: Mark Stamnes; Giampietro Schiavo; G Stenbeck; Thomas H Söllner; James E Rothman
ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13676-80.
1998: Tobias M Hohl; Francesco Parlati; C Wimmer; James E Rothman; Thomas H Söllner; H Engelhardt
Arrangement of subunits in 20 S particles consisting of NSF, SNAPs, and SNARE complexes.
Molecular cell 1998;2(5):539-48.
1998: Dino A De Angelis; Gero Miesenböck; Boris V Zemelman; James E Rothman
PRIM: proximity imaging of green fluorescent protein-tagged polypeptides.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12312-6.
1998: Gero Miesenböck; Dino A De Angelis; James E Rothman
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins.
Nature 1998;394(6689):192-5.
1998: Thomas Weber; Boris V Zemelman; James A McNew; B Westermann; M Gmachl; Francesco Parlati; Thomas H Söllner; James E Rothman
SNAREpins: minimal machinery for membrane fusion.
Cell 1998;92(6):759-72.
1998: Lelio Orci; Alain Perrelet; James E Rothman
Vesicles on strings: morphological evidence for processive transport within the Golgi stack.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2279-83.
1997: Klaus Fiedler; James E Rothman
Sorting determinants in the transmembrane domain of p24 proteins.
The Journal of biological chemistry 1997;272(40):24739-42.
1997: Lelio Orci; Mark Stamnes; Mariella Ravazzola; Mylene Amherdt; Alain Perrelet; Thomas H Söllner; James E Rothman
Bidirectional transport by distinct populations of COPI-coated vesicles.
Cell 1997;90(2):335-49.
1997: James A McNew; M Sogaard; Nina Lampen; S Machida; R R Ye; Lynne Lacomis; Paul Tempst; James E Rothman; Thomas H Söllner
Ykt6p, a prenylated SNARE essential for endoplasmic reticulum-Golgi transport.
The Journal of biological chemistry 1997;272(28):17776-83.
1997: I Paek; Lelio Orci; Mariella Ravazzola; Hediye Erdjument-Bromage; Mylene Amherdt; Paul Tempst; Thomas H Söllner; James E Rothman
ERS-24, a mammalian v-SNARE implicated in vesicle traffic between the ER and the Golgi.
The Journal of cell biology 1997;137(5):1017-28.
1997: James E Rothman; Thomas H Söllner
Throttles and dampers: controlling the engine of membrane fusion.
Science (New York, N.Y.) 1997;276(5316):1212-3.
1997: Gero Miesenböck; James E Rothman
Patterns of synaptic activity in neural networks recorded by light emission from synaptolucins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3402-7.
1997: Giampietro Schiavo; G Stenbeck; James E Rothman; Thomas H Söllner
Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(3):997-1001.
1996: Thomas H Söllner; James E Rothman
Molecular machinery mediating vesicle budding, docking and fusion.
Experientia 1996;52(12):1021-5.
1996: Giampietro Schiavo; Q M Gu; G D Prestwich; Thomas H Söllner; James E Rothman
Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13327-32.
1996: Thomas H Söllner; James E Rothman
Molecular machinery mediating vesicle budding, docking and fusion.
Cell structure and function 1996;21(5):407-12.
1996: Klaus Fiedler; Michael Veit; Mark Stamnes; James E Rothman
Bimodal interaction of coatomer with the p24 family of putative cargo receptors.
Science (New York, N.Y.) 1996;273(5280):1396-9.
1996: M Nagahama; L Orci; Mariella Ravazzola; Mylene Amherdt; Lynne Lacomis; Paul Tempst; James E Rothman; Thomas H Söllner
A v-SNARE implicated in intra-Golgi transport.
The Journal of cell biology 1996;133(3):507-16.
1996: Michael Veit; Thomas H Söllner; James E Rothman
Multiple palmitoylation of synaptotagmin and the t-SNARE SNAP-25.
FEBS letters 1996;385(1-2):119-23.
1996: James E Rothman; Felix T Wieland
Protein sorting by transport vesicles.
Science (New York, N.Y.) 1996;272(5259):227-34.
1996: James E Rothman
The protein machinery of vesicle budding and fusion.
Protein science : a publication of the Protein Society 1996;5(2):185-94.
1995: Giampietro Schiavo; M J Gmachl; G Stenbeck; Thomas H Söllner; James E Rothman
A possible docking and fusion particle for synaptic transmission.
Nature 1995;378(6558):733-6.
1995: Mark Stamnes; M W Craighead; M H Hoe; N Lampen; S Geromanos; Paul Tempst; James E Rothman
An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):8011-5.
1995: Gero Miesenböck; James E Rothman
The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack.
The Journal of cell biology 1995;129(2):309-19.
1994: L Orci; Alain Perrelet; Mariella Ravazzola; Mylene Amherdt; James E Rothman; Randy Schekman
Coatomer-rich endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(25):11924-8.
1994: James E Rothman
Mechanisms of intracellular protein transport.
Nature 1994;372(6501):55-63.
1994: M Søgaard; K Tani; R R Ye; S Geromanos; Paul Tempst; T Kirchhausen; James E Rothman; Thomas H Söllner
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles.
Cell 1994;78(6):937-48.
1994: S W Whiteheart; K Rossnagel; S A Buhrow; M Brunner; R Jaenicke; James E Rothman
N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion.
The Journal of cell biology 1994;126(4):945-54.
1994: Thomas H Söllner; James E Rothman
Neurotransmission: harnessing fusion machinery at the synapse.
Trends in neurosciences 1994;17(8):344-8.
1994: O Kuge; C Dascher; L Orci; T Rowe; Mylene Amherdt; Helen Plutner; Mariella Ravazzola; G Tanigawa; James E Rothman; William E Balch
Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments.
The Journal of cell biology 1994;125(1):51-65.
1994: S Hara-Kuge; O Kuge; L Orci; Mylene Amherdt; Mariella Ravazzola; Felix T Wieland; James E Rothman
En bloc incorporation of coatomer subunits during the assembly of COP-coated vesicles.
The Journal of cell biology 1994;124(6):883-92.
1994: James E Rothman; G Warren
Implications of the SNARE hypothesis for intracellular membrane topology and dynamics.
Current biology : CB 1994;4(3):220-33.
1994: Z Elazar; L Orci; J Ostermann; Mylene Amherdt; G Tanigawa; James E Rothman
ADP-ribosylation factor and coatomer couple fusion to vesicle budding.
The Journal of cell biology 1994;124(4):415-24.
1994: Z Elazar; T Mayer; James E Rothman
Removal of Rab GTP-binding proteins from Golgi membranes by GDP dissociation inhibitor inhibits inter-cisternal transport in the Golgi stacks.
The Journal of biological chemistry 1994;269(2):794-7.
1993: J Ostermann; L Orci; K Tani; Mylene Amherdt; Mariella Ravazzola; Z Elazar; James E Rothman
Stepwise assembly of functionally active transport vesicles.
Cell 1993;75(5):1015-25.
1993: O Kuge; S Hara-Kuge; L Orci; Mariella Ravazzola; Mylene Amherdt; G Tanigawa; Felix T Wieland; James E Rothman
zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly.
The Journal of cell biology 1993;123(6 Pt 2):1727-34.
1993: G Tanigawa; L Orci; Mylene Amherdt; Mariella Ravazzola; J Bernd Helms; James E Rothman
Hydrolysis of bound GTP by ARF protein triggers uncoating of Golgi-derived COP-coated vesicles.
The Journal of cell biology 1993;123(6 Pt 1):1365-71.
1993: L Orci; Alain Perrelet; Mariella Ravazzola; F T Wieland; Randy Schekman; James E Rothman
"BFA bodies": a subcompartment of the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11089-93.
1993: Thomas H Söllner; M K Bennett; S W Whiteheart; R H Scheller; James E Rothman
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion.
Cell 1993;75(3):409-18.
1993: L Orcl; D J Palmer; Mylene Amherdt; James E Rothman
Coated vesicle assembly in the Golgi requires only coatomer and ARF proteins from the cytosol.
Nature 1993;364(6439):732-4.
1993: D J Palmer; J Bernd Helms; Cornelis Beckers; L Orci; James E Rothman
Binding of coatomer to Golgi membranes requires ADP-ribosylation factor.
The Journal of biological chemistry 1993;268(16):12083-9.
1993: Mark Stamnes; James E Rothman
The binding of AP-1 clathrin adaptor particles to Golgi membranes requires ADP-ribosylation factor, a small GTP-binding protein.
Cell 1993;73(5):999-1005.
1993: J Bernd Helms; D J Palmer; James E Rothman
Two distinct populations of ARF bound to Golgi membranes.
The Journal of cell biology 1993;121(4):751-60.
1993: L Orci; D J Palmer; Mariella Ravazzola; Alain Perrelet; Mylene Amherdt; James E Rothman
Budding from Golgi membranes requires the coatomer complex of non-clathrin coat proteins.
Nature 1993;362(6421):648-52.
1993: S W Whiteheart; I C Griff; M Brunner; D O Clary; T Mayer; S A Buhrow; James E Rothman
SNAP family of NSF attachment proteins includes a brain-specific isoform.
Nature 1993;362(6418):353-5.
1993: Thomas H Söllner; S W Whiteheart; M Brunner; Hediye Erdjument-Bromage; S Geromanos; Paul Tempst; James E Rothman
SNAP receptors implicated in vesicle targeting and fusion.
Nature 1993;362(6418):318-24.
1993: M Tagaya; D W Wilson; M Brunner; N Arango; James E Rothman
Domain structure of an N-ethylmaleimide-sensitive fusion protein involved in vesicular transport.
The Journal of biological chemistry 1993;268(4):2662-6.
1992: G Stenbeck; R Schreiner; D Herrmann; S Auerbach; F Lottspeich; James E Rothman; Felix T Wieland
Gamma-COP, a coat subunit of non-clathrin-coated vesicles with homology to Sec21p.
FEBS letters 1992;314(2):195-8.
1992: J Bernd Helms; James E Rothman
Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF.
Nature 1992;360(6402):352-4.
1992: M G Waters; D O Clary; James E Rothman
A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack.
The Journal of cell biology 1992;118(5):1015-26.
1992: Richard A Kahn; Paul A Randazzo; T Serafini; O Weiss; C Rulka; J Clark; Mylene Amherdt; Peter P Roller; L Orci; James E Rothman
The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport.
The Journal of biological chemistry 1992;267(18):13039-46.
1992: S W Whiteheart; M Brunner; D W Wilson; M Wiedmann; James E Rothman
Soluble N-ethylmaleimide-sensitive fusion attachment proteins (SNAPs) bind to a multi-SNAP receptor complex in Golgi membranes.
The Journal of biological chemistry 1992;267(17):12239-43.
1992: D W Wilson; S W Whiteheart; M Wiedmann; M Brunner; James E Rothman
A multisubunit particle implicated in membrane fusion.
The Journal of cell biology 1992;117(3):531-8.
1992: James E Rothman; L Orci
Molecular dissection of the secretory pathway.
Nature 1992;355(6359):409-15.
1992: M Gerard Waters; Cornelis Beckers; James E Rothman
Purification of coat protomers.
Methods in enzymology 1992;219():331-7.
1991: G C Flynn; J Pohl; M T Flocco; James E Rothman
Peptide-binding specificity of the molecular chaperone BiP.
Nature 1991;353(6346):726-30.
1991: T Serafini; L Orci; Mylene Amherdt; M Brunner; Richard A Kahn; James E Rothman
ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein.
Cell 1991;67(2):239-53.
1991: D W Wilson; S W Whiteheart; L Orci; James E Rothman
Intracellular membrane fusion.
Trends in biochemical sciences 1991;16(9):334-7.
1991: M Gerard Waters; I C Griff; James E Rothman
Proteins involved in vesicular transport and membrane fusion.
Current opinion in cell biology 1991;3(4):615-20.
1991: L Orci; M Tagaya; Mylene Amherdt; Alain Perrelet; Julie G Donaldson; Jennifer Lippincott-Schwartz; R D Klausner; James E Rothman
Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae.
Cell 1991;64(6):1183-95.
1991: James E Rothman
Enzymology of intracellular membrane fusion.
Klinische Wochenschrift 1991;69(3):98-104.
1991: M Gerard Waters; T Serafini; James E Rothman
'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles.
Nature 1991;349(6306):248-51.
1991: T Serafini; G Stenbeck; A Brecht; F Lottspeich; L Orci; James E Rothman; Felix T Wieland
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin.
Nature 1991;349(6306):215-20.
1990: J Bernd Helms; A Karrenbauer; Karel W A Wirtz; James E Rothman; Felix T Wieland
Reconstitution of steps in the constitutive secretory pathway in permeabilized cells. Secretion of glycosylated tripeptide and truncated sphingomyelin.
The Journal of biological chemistry 1990;265(32):20027-32.
1990: A Karrenbauer; D Jeckel; Wilhelm W Just; R Birk; R R Schmidt; James E Rothman; Felix T Wieland
The rate of bulk flow from the Golgi to the plasma membrane.
Cell 1990;63(2):259-67.
1990: D O Clary; James E Rothman
Purification of three related peripheral membrane proteins needed for vesicular transport.
The Journal of biological chemistry 1990;265(17):10109-17.
1990: D O Clary; I C Griff; James E Rothman
SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast.
Cell 1990;61(4):709-21.
1990: N Pfanner; Benjamin S Glick; S R Arden; James E Rothman
Fatty acylation promotes fusion of transport vesicles with Golgi cisternae.
The Journal of cell biology 1990;110(4):955-61.
1989: James E Rothman
Polypeptide chain binding proteins: catalysts of protein folding and related processes in cells.
Cell 1989;59(4):591-601.
1989: N Pfanner; L Orci; Benjamin S Glick; M Amherdt; S R Arden; V Malhotra; James E Rothman
Fatty acyl-coenzyme A is required for budding of transport vesicles from Golgi cisternae.
Cell 1989;59(1):95-102.
1989: G C Flynn; T G Chappell; James E Rothman
Peptide binding and release by proteins implicated as catalysts of protein assembly.
Science (New York, N.Y.) 1989;245(4916):385-90.
1989: V Malhotra; T Serafini; L Orci; J C Shepherd; James E Rothman
Purification of a novel class of coated vesicles mediating biosynthetic protein transport through the Golgi stack.
Cell 1989;58(2):329-36.
1989: D W Wilson; C A Wilcox; G C Flynn; E Chen; W J Kuang; william james Henzel; M R Block; A Ullrich; James E Rothman
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast.
Nature 1989;339(6223):355-9.
1989: Cornelis Beckers; M R Block; Benjamin S Glick; James E Rothman; W E Balch
Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein.
Nature 1989;339(6223):397-8.
1989: P J Weidman; Paul Melançon; M R Block; James E Rothman
Binding of an N-ethylmaleimide-sensitive fusion protein to Golgi membranes requires both a soluble protein(s) and an integral membrane receptor.
The Journal of cell biology 1989;108(5):1589-96.
1989: L Orci; V Malhotra; Mylene Amherdt; T Serafini; James E Rothman
Dissection of a single round of vesicular transport: sequential intermediates for intercisternal movement in the Golgi stack.
Cell 1989;56(3):357-68.
1989: Paul Melançon; Benjamin S Glick; V Malhotra; P J Weidman; T Serafini; L Orci; James E Rothman
A role for GTP-binding proteins in vesicular transport through the Golgi complex.
Society of General Physiologists series 1989;44():175-88.
1988: M R Block; Benjamin S Glick; C A Wilcox; Felix T Wieland; James E Rothman
Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(21):7852-6.
1988: V Malhotra; L Orci; Benjamin S Glick; M R Block; James E Rothman
Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack.
Cell 1988;54(2):221-7.
1987: Paul Melançon; Benjamin S Glick; V Malhotra; P J Weidman; T Serafini; M L Gleason; L Orci; James E Rothman
Involvement of GTP-binding "G" proteins in transport through the Golgi stack.
Cell 1987;51(6):1053-62.
1987: F T Wieland; M L Gleason; T A Serafini; James E Rothman
The rate of bulk flow from the endoplasmic reticulum to the cell surface.
Cell 1987;50(2):289-300.