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Peter Rotwein

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
8
Kuninger, David
8
Wilson, Elizabeth
7
Woelfle, Joachim
7
McCarthy, Thomas
7
Centrella, Michael
6
Chia, Dennis
5
Billiard, Julia
5
Umayahara, Y
4
Permutt, Alan
4
Mukherjee, Aditi
3
Pintar, John
3
Ono, Mitsuru
3
Tureckova, Jolana
3
Kuns-Hashimoto, Robin
3
Hammerman, Marc

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Publications

TOP 3
Severyn Christopher J; Shinde Ujwal; Rotwein Peter
Molecular biology, genetics and biochemistry of the repulsive guidance molecule family.
Chen Yu; Sood Sumita; Krishnamurthy Vidya M R; Rotwein Peter; Rabkin Ralph
Endotoxin-induced growth hormone resistance in skeletal muscle.
Rotwein Peter; Wilson Elizabeth M
Distinct actions of Akt1 and Akt2 in skeletal muscle differentiation.

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All Publications

2009: Severyn Christopher J; Shinde Ujwal; Rotwein Peter
Molecular biology, genetics and biochemistry of the repulsive guidance molecule family.
The Biochemical journal 2009;422(3):393-403.
2009: Chen Yu; Sood Sumita; Krishnamurthy Vidya M R; Rotwein Peter; Rabkin Ralph
Endotoxin-induced growth hormone resistance in skeletal muscle.
Endocrinology 2009;150(8):3620-6.
2009: Rotwein Peter; Wilson Elizabeth M
Distinct actions of Akt1 and Akt2 in skeletal muscle differentiation.
Journal of cellular physiology 2009;219(2):503-11.
2009: Mukherjee Aditi; Rotwein Peter
Akt promotes BMP2-mediated osteoblast differentiation and bone development.
Journal of cell science 2009;122(Pt 5):716-26.
2008: Mukherjee Aditi; Rotwein Peter
Insulin-like growth factor-binding protein-5 inhibits osteoblast differentiation and skeletal growth by blocking insulin-like growth factor actions.
Molecular endocrinology (Baltimore, Md.) 2008;22(5):1238-50.
2008: Kuns-Hashimoto Robin; Kuninger David; Nili Mahta; Rotwein Peter
Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin.
American journal of physiology. Cell physiology 2008;294(4):C994-C1003.
2008: Mukherjee Aditi; Wilson Elizabeth M; Rotwein Peter
Insulin-like growth factor (IGF) binding protein-5 blocks skeletal muscle differentiation by inhibiting IGF actions.
Molecular endocrinology (Baltimore, Md.) 2008;22(1):206-15.
2008: Kuninger David; Kuns-Hashimoto Robin; Nili Mahta; Rotwein Peter
Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin.
BMC biochemistry 2008;9():9.
2007: Kuninger David; Lundblad James; Semirale Anthony; Rotwein Peter
A non-isotopic in vitro assay for histone acetylation.
Journal of biotechnology 2007;131(3):253-60.
2007: Ono Mitsuru; Chia Dennis J; Merino-Martinez Roxana; Flores-Morales Amilcar; Unterman Terry G; Rotwein Peter
Signal transducer and activator of transcription (Stat) 5b-mediated inhibition of insulin-like growth factor binding protein-1 gene transcription: a mechanism for repression of gene expression by growth hormone.
Molecular endocrinology (Baltimore, Md.) 2007;21(6):1443-57.
2007: Mukherjee Aditi; Rotwein Peter
Insulin-like growth factor binding protein-5 in osteogenesis: facilitator or inhibitor?
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2007;17(3):179-85.
2007: Wilson Elizabeth M; Rotwein Peter
Selective control of skeletal muscle differentiation by Akt1.
The Journal of biological chemistry 2007;282(8):5106-10.
2007: Vidal Oscar M; Merino Roxana; Rico-Bautista Elizabeth; Fernandez-Perez Leandro; Chia Dennis J; Woelfle Joachim; Ono Mitsuru; Lenhard Boris; Norstedt Gunnar; Rotwein Peter; Flores-Morales Amilcar
In vivo transcript profiling and phylogenetic analysis identifies suppressor of cytokine signaling 2 as a direct signal transducer and activator of transcription 5b target in liver.
Molecular endocrinology (Baltimore, Md.) 2007;21(1):293-311.
2006: Wilson Elizabeth M; Rotwein Peter
Control of MyoD function during initiation of muscle differentiation by an autocrine signaling pathway activated by insulin-like growth factor-II.
The Journal of biological chemistry 2006;281(40):29962-71.
2006: Kuninger David; Wright Alistair; Rotwein Peter
Muscle cell survival mediated by the transcriptional coactivators p300 and PCAF displays different requirements for acetyltransferase activity.
American journal of physiology. Cell physiology 2006;291(4):C699-709.
2006: Ning Yun; Schuller Alwin G P; Bradshaw Sheri; Rotwein Peter; Ludwig Thomas; Frystyk Jan; Pintar John E
Diminished growth and enhanced glucose metabolism in triple knockout mice containing mutations of insulin-like growth factor binding protein-3, -4, and -5.
Molecular endocrinology (Baltimore, Md.) 2006;20(9):2173-86.
2006: Mak R H; Rotwein P
Myostatin and insulin-like growth factors in uremic sarcopenia: the yin and yang in muscle mass regulation.
Kidney international 2006;70(3):410-2.
2006: Kuninger David; Kuns-Hashimoto Robin; Kuzmickas Ryan; Rotwein Peter
Complex biosynthesis of the muscle-enriched iron regulator RGMc.
Journal of cell science 2006;119(Pt 16):3273-83.
2006: Ahmed Tamer; Yumet Gladys; Shumate Margaret; Lang Charles H; Rotwein Peter; Cooney Robert N
Tumor necrosis factor inhibits growth hormone-mediated gene expression in hepatocytes.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(1):G35-44.
2006: Chia Dennis J; Subbian Ezhilkani; Buck Teresa M; Hwa Vivian; Rosenfeld Ron G; Skach William R; Shinde Ujwal; Rotwein Peter
Aberrant folding of a mutant Stat5b causes growth hormone insensitivity and proteasomal dysfunction.
The Journal of biological chemistry 2006;281(10):6552-8.
2006: Chia Dennis J; Ono Mitsuru; Woelfle Joachim; Schlesinger-Massart Mylynda; Jiang Honglin; Rotwein Peter
Characterization of distinct Stat5b binding sites that mediate growth hormone-stimulated IGF-I gene transcription.
The Journal of biological chemistry 2006;281(6):3190-7.
2005: Woelfle Joachim; Chia Dennis J; Massart-Schlesinger Mylynda B; Moyano Paula; Rotwein Peter
Molecular physiology, pathology, and regulation of the growth hormone/insulin-like growth factor-I system.
Pediatric nephrology (Berlin, Germany) 2005;20(3):295-302.
2004: Kuninger David; Stauffer Daniel; Eftekhari Siavash; Wilson Elizabeth; Thayer Mathew; Rotwein Peter
Gene disruption by regulated short interfering RNA expression, using a two-adenovirus system.
Human gene therapy 2004;15(12):1287-92.
2004: Moyano Paula; Rotwein Peter
Mini-review: estrogen action in the uterus and insulin-like growth factor-I.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2004;14(6):431-5.
2004: Kuninger David; Kuzmickas Ryan; Peng Bonnie; Pintar John E; Rotwein Peter
Gene discovery by microarray: identification of novel genes induced during growth factor-mediated muscle cell survival and differentiation.
Genomics 2004;84(5):876-89.
2004: Woelfle Joachim; Rotwein Peter
In vivo regulation of growth hormone-stimulated gene transcription by STAT5b.
American journal of physiology. Endocrinology and metabolism 2004;286(3):E393-401.
2004: Wilson Elizabeth M; Tureckova Jolana; Rotwein Peter
Permissive roles of phosphatidyl inositol 3-kinase and Akt in skeletal myocyte maturation.
Molecular biology of the cell 2004;15(2):497-505.
2003: Rotwein Peter
Insulin-like growth factor action and skeletal muscle growth, an in vivo perspective.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2003;13(6):303-5.
2003: Woelfle Joachim; Chia Dennis J; Rotwein Peter
Mechanisms of growth hormone (GH) action. Identification of conserved Stat5 binding sites that mediate GH-induced insulin-like growth factor-I gene activation.
The Journal of biological chemistry 2003;278(51):51261-6.
2003: Wilson Elizabeth M; Hsieh Marlene M; Rotwein Peter
Autocrine growth factor signaling by insulin-like growth factor-II mediates MyoD-stimulated myocyte maturation.
The Journal of biological chemistry 2003;278(42):41109-13.
2003: Woelfle Joachim; Billiard Julia; Rotwein Peter
Acute control of insulin-like growth factor-I gene transcription by growth hormone through Stat5b.
The Journal of biological chemistry 2003;278(25):22696-702.
2003: Zeng Shelya X; Jin Yetao; Kuninger David T; Rotwein Peter; Lu Hua
The acetylase activity of p300 is dispensable for MDM2 stabilization.
The Journal of biological chemistry 2003;278(9):7453-8.
2002: Rotwein Peter; Billiard Julia; Woelfle Joachim
Molecular physiology of IGF-I expression.
Journal of pediatric endocrinology & metabolism : JPEM 2002;15 Suppl 5():1455-8.
2001: Tureckova J; Wilson E M; Cappalonga J L; Rotwein P
Insulin-like growth factor-mediated muscle differentiation: collaboration between phosphatidylinositol 3-kinase-Akt-signaling pathways and myogenin.
The Journal of biological chemistry 2001;276(42):39264-70.
2001: Billiard J; Grewal S S; Lukaesko L; Stork P J; Rotwein P
Hormonal control of insulin-like growth factor I gene transcription in human osteoblasts: dual actions of cAMP-dependent protein kinase on CCAAT/enhancer-binding protein delta.
The Journal of biological chemistry 2001;276(33):31238-46.
2001: Billiard J; Umayahara Y; Wiren K; Centrella M; McCarthy T L; Rotwein P
Regulated nuclear-cytoplasmic localization of CCAAT/enhancer-binding protein delta in osteoblasts.
The Journal of biological chemistry 2001;276(18):15354-61.
2000: Lawlor M A; Rotwein P
Coordinate control of muscle cell survival by distinct insulin-like growth factor activated signaling pathways.
The Journal of cell biology 2000;151(6):1131-40.
2000: Lawlor M A; Rotwein P
Insulin-like growth factor-mediated muscle cell survival: central roles for Akt and cyclin-dependent kinase inhibitor p21.
Molecular and cellular biology 2000;20(23):8983-95.
2000: Delling U; Tureckova J; Lim H W; De Windt L J; Rotwein P; Molkentin J D
A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression.
Molecular and cellular biology 2000;20(17):6600-11.
2000: Lawlor M A; Feng X; Everding D R; Sieger K; Stewart C E; Rotwein P
Dual control of muscle cell survival by distinct growth factor-regulated signaling pathways.
Molecular and cellular biology 2000;20(9):3256-65.
1999: Umayahara Y; Billiard J; Ji C; Centrella M; McCarthy T L; Rotwein P
CCAAT/enhancer-binding protein delta is a critical regulator of insulin-like growth factor-I gene transcription in osteoblasts.
The Journal of biological chemistry 1999;274(15):10609-17.
1999: Rotwein P
Human growth disorders: molecular genetics of the growth hormone-insulin-like growth factor I axis.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1999;88(428):148-51; discussion 152.
1998: Le Stunff C; Rotwein P
Growth hormone stimulates interferon regulatory factor-1 gene expression in the liver.
Endocrinology 1998;139(3):859-66.
1997: Umayahara Y; Ji C; Centrella M; Rotwein P; McCarthy T L
CCAAT/enhancer-binding protein delta activates insulin-like growth factor-I gene transcription in osteoblasts. Identification of a novel cyclic AMP signaling pathway in bone.
The Journal of biological chemistry 1997;272(50):31793-800.
1997: Ye P; Umayahara Y; Ritter D; Bunting T; Auman H; Rotwein P; D'Ercole A J
Regulation of insulin-like growth factor I (IGF-I) gene expression in brain of transgenic mice expressing an IGF-I-luciferase fusion gene.
Endocrinology 1997;138(12):5466-75.
1997: McCarthy T L; Ji C; Shu H; Casinghino S; Crothers K; Rotwein P; Centrella M
17beta-estradiol potently suppresses cAMP-induced insulin-like growth factor-I gene activation in primary rat osteoblast cultures.
The Journal of biological chemistry 1997;272(29):18132-9.
1997: Stewart C L; Pedersen R; Rotwein P; Bestor T; Rastan S; Hastie N; Nichols R; Mutter G
NIEHS/EPA Workshops. Genomic imprinting.
Reproductive toxicology (Elmsford, N.Y.) 1997;11(2-3):309-16.
1997: Bui T; Kuo C; Rotwein P; Straus D S
Prostaglandin A2 specifically represses insulin-like growth factor-I gene expression in C6 rat glioma cells.
Endocrinology 1997;138(3):985-93.
1997: Mittanck D W; Kim S W; Rotwein P
Essential promoter elements are located within the 5' untranslated region of human insulin-like growth factor-I exon I.
Molecular and cellular endocrinology 1997;126(2):153-63.
1997: Strous G J; van Kerkhof P; Govers R; Rotwein P; Schwartz A L
Growth hormone-induced signal tranduction depends on an intact ubiquitin system.
The Journal of biological chemistry 1997;272(1):40-3.
1996: Sasaki H; Shimozaki K; Zubair M; Aoki N; Ohta K; Hatano N; Moore T; Feil R; Constancia M; Reik W; Rotwein P
Nucleotide sequence of a 28-kb mouse genomic region comprising the imprinted Igf2 gene.
DNA research : an international journal for rapid publication of reports on genes and genomes 1996;3(5):331-5.
1996: Stewart C E; Rotwein P
Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors.
Physiological reviews 1996;76(4):1005-26.
1996: Stewart C E; James P L; Fant M E; Rotwein P
Overexpression of insulin-like growth factor-II induces accelerated myoblast differentiation.
Journal of cellular physiology 1996;169(1):23-32.
1996: Thomas M J; Umayahara Y; Shu H; Centrella M; Rotwein P; McCarthy T L
Identification of the cAMP response element that controls transcriptional activation of the insulin-like growth factor-I gene by prostaglandin E2 in osteoblasts.
The Journal of biological chemistry 1996;271(36):21835-41.
1996: Le Stunff C; Gronowski A M; Rotwein P
Contrasting acute in vivo nuclear actions of growth hormone and prolactin.
Molecular and cellular endocrinology 1996;121(2):109-17.
1996: James P L; Stewart C E; Rotwein P
Insulin-like growth factor binding protein-5 modulates muscle differentiation through an insulin-like growth factor-dependent mechanism.
The Journal of cell biology 1996;133(3):683-93.
1996: Stewart C E; Rotwein P
Insulin-like growth factor-II is an autocrine survival factor for differentiating myoblasts.
The Journal of biological chemistry 1996;271(19):11330-8.
1996: McCarthy T L; Casinghino S; Mittanck D W; Ji C H; Centrella M; Rotwein P
Promoter-dependent and -independent activation of insulin-like growth factor binding protein-5 gene expression by prostaglandin E2 in primary rat osteoblasts.
The Journal of biological chemistry 1996;271(12):6666-71.
1996: Gronowski A M; Le Stunff C; Rotwein P
Acute nuclear actions of growth hormone (GH): cycloheximide inhibits inducible activator protein-1 activity, but does not block GH-regulated signal transducer and activator of transcription activation or gene expression.
Endocrinology 1996;137(1):55-64.
1995: Liu Z; Mittanck D W; Kim S; Rotwein P
Control of insulin-like growth factor-II/mannose 6-phosphate receptor gene transcription by proximal promoter elements.
Molecular endocrinology (Baltimore, Md.) 1995;9(11):1477-87.
1995: Gronowski A M; Rotwein P
Rapid changes in gene expression after in vivo growth hormone treatment.
Endocrinology 1995;136(11):4741-8.
1995: McCarthy T L; Thomas M J; Centrella M; Rotwein P
Regulation of insulin-like growth factor I transcription by cyclic adenosine 3',5'-monophosphate (cAMP) in fetal rat bone cells through an element within exon 1: protein kinase A-dependent control without a consensus AMP response element.
Endocrinology 1995;136(9):3901-8.
1995: Rotwein P; James P L; Kou K
Rapid activation of insulin-like growth factor binding protein-5 gene transcription during myoblast differentiation.
Molecular endocrinology (Baltimore, Md.) 1995;9(7):913-23.
1995: Le Stunff C; Thomas M J; Rotwein P
Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no changes in deoxyribonucleic acid-protein interactions within the second promoter.
Endocrinology 1995;136(5):2230-7.
1995: Kou K; Mittanck D W; Fu C; Rotwein P
Structure and function of the mouse insulin-like growth factor binding protein 5 gene promoter.
DNA and cell biology 1995;14(3):241-9.
1995: Thomas M J; Kikuchi K; Bichell D P; Rotwein P
Characterization of deoxyribonucleic acid-protein interactions at a growth hormone-inducible nuclease hypersensitive site in the rat insulin-like growth factor-I gene.
Endocrinology 1995;136(2):562-9.
1995: Gronowski A M; Zhong Z; Wen Z; Thomas M J; Darnell J E; Rotwein P
In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3.
Molecular endocrinology (Baltimore, Md.) 1995;9(2):171-7.
1995: Thomas M J; Gronowski A M; Berry S A; Bergad P L; Rotwein P
Growth hormone rapidly activates rat serine protease inhibitor 2.1 gene transcription and induces a DNA-binding activity distinct from those of Stat1, -3, and -4.
Molecular and cellular biology 1995;15(1):12-8.
1994: Lau M M; Stewart C E; Liu Z; Bhatt H; Rotwein P; Stewart C L
Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality.
Genes & development 1994;8(24):2953-63.
1994: Thomas M J; Kikuchi K; Bichell D P; Rotwein P
Rapid activation of rat insulin-like growth factor-I gene transcription by growth hormone reveals no alterations in deoxyribonucleic acid-protein interactions within the major promoter.
Endocrinology 1994;135(4):1584-92.
1994: Kou K; James P L; Clemmons D R; Copeland N G; Gilbert D J; Jenkins N A; Rotwein P
Identification of two clusters of mouse insulin-like growth factor binding protein genes on chromosomes 1 and 11.
Genomics 1994;21(3):653-5.
1994: Kou K; Jenkins N A; Gilbert D J; Copeland N G; Rotwein P
Organization, expression, and chromosomal location of the mouse insulin-like growth factor binding protein 5 gene.
Genomics 1994;20(3):412-8.
1994: Gronowski A M; Rotwein P
Rapid changes in nuclear protein tyrosine phosphorylation after growth hormone treatment in vivo. Identification of phosphorylated mitogen-activated protein kinase and STAT91.
The Journal of biological chemistry 1994;269(11):7874-8.
1994: Green B N; Jones S B; Streck R D; Wood T L; Rotwein P; Pintar J E
Distinct expression patterns of insulin-like growth factor binding proteins 2 and 5 during fetal and postnatal development.
Endocrinology 1994;134(2):954-62.
1994: Szebenyi G; Rotwein P
The mouse insulin-like growth factor II/cation-independent mannose 6-phosphate (IGF-II/MPR) receptor gene: molecular cloning and genomic organization.
Genomics 1994;19(1):120-9.
1994: Rotwein P; Gronowski A M; Thomas M J
Rapid nuclear actions of growth hormone.
Hormone research 1994;42(4-5):170-5.
1993: James P L; Jones S B; Busby W H; Clemmons D R; Rotwein P
A highly conserved insulin-like growth factor-binding protein (IGFBP-5) is expressed during myoblast differentiation.
The Journal of biological chemistry 1993;268(30):22305-12.
1993: Bichell D P; Rotwein P; McCarthy T L
Prostaglandin E2 rapidly stimulates insulin-like growth factor-I gene expression in primary rat osteoblast cultures: evidence for transcriptional control.
Endocrinology 1993;133(3):1020-8.
1993: Rotwein P; Bichell D P; Kikuchi K
Multifactorial regulation of IGF-I gene expression.
Molecular reproduction and development 1993;35(4):358-63; discussion 363-4.
1993: Kou K; Rotwein P
Transcriptional activation of the insulin-like growth factor-II gene during myoblast differentiation.
Molecular endocrinology (Baltimore, Md.) 1993;7(2):291-302.
1993: Kou K; Lajara R; Rotwein P
Amino acid substitutions in the intracellular part of the growth hormone receptor in a patient with the Laron syndrome.
The Journal of clinical endocrinology and metabolism 1993;76(1):54-9.
1992: Bichell D P; Kikuchi K; Rotwein P
Growth hormone rapidly activates insulin-like growth factor I gene transcription in vivo.
Molecular endocrinology (Baltimore, Md.) 1992;6(11):1899-908.
1992: Greenwald J E; Ritter D; Tetens E; Rotwein P S
Renal expression of the gene for atrial natriuretic factor.
The American journal of physiology 1992;263(5 Pt 2):F974-8.
1992: Kikuchi K; Bichell D P; Rotwein P
Chromatin changes accompany the developmental activation of insulin-like growth factor I gene transcription.
The Journal of biological chemistry 1992;267(30):21505-11.
1992: Hall L J; Kajimoto Y; Bichell D; Kim S W; James P L; Counts D; Nixon L J; Tobin G; Rotwein P
Functional analysis of the rat insulin-like growth factor I gene and identification of an IGF-I gene promoter.
DNA and cell biology 1992;11(4):301-13.
1991: Kim S W; Lajara R; Rotwein P
Structure and function of a human insulin-like growth factor-I gene promoter.
Molecular endocrinology (Baltimore, Md.) 1991;5(12):1964-72.
1991: Florini J R; Magri K A; Ewton D Z; James P L; Grindstaff K; Rotwein P S
"Spontaneous" differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II.
The Journal of biological chemistry 1991;266(24):15917-23.
1991: Kajimoto Y; Rotwein P
Structure of the chicken insulin-like growth factor I gene reveals conserved promoter elements.
The Journal of biological chemistry 1991;266(15):9724-31.
1991: Kikuchi K; Buonomo F C; Kajimoto Y; Rotwein P
Expression of insulin-like growth factor-I during chicken development.
Endocrinology 1991;128(3):1323-8.
1991: Szebenyi G; Rotwein P
Differential regulation of mannose 6-phosphate receptors and their ligands during the myogenic development of C2 cells.
The Journal of biological chemistry 1991;266(9):5534-9.
1991: Rotwein P
Structure, evolution, expression and regulation of insulin-like growth factors I and II.
Growth factors (Chur, Switzerland) 1991;5(1):3-18.
1991: Szebenyi G; Rotwein P
Insulin-like growth factors and their receptors in muscle development.
Advances in experimental medicine and biology 1991;293():289-95.
1990: Tobin G; Yee D; Brünner N; Rotwein P
A novel human insulin-like growth factor I messenger RNA is expressed in normal and tumor cells.
Molecular endocrinology (Baltimore, Md.) 1990;4(12):1914-20.
1990: Rotwein P; Hall L J
Evolution of insulin-like growth factor II: characterization of the mouse IGF-II gene and identification of two pseudo-exons.
DNA and cell biology 1990;9(10):725-35.
1990: Dempsher D P; Bier D M; Tollefsen S E; Rotwein P S; Daughaday W H; Jensen M C; Galgani J P; Heath-Monnig E; Trivedi B
Whole body nitrogen kinetics and their relationship to growth in short children treated with recombinant human growth hormone.
Pediatric research 1990;28(4):394-400.
1990: Miller S B; Rotwein P; Bortz J D; Bechtel P J; Hansen V A; Rogers S A; Hammerman M R
Renal expression of IGF I in hypersomatotropic states.
The American journal of physiology 1990;259(2 Pt 2):F251-7.
1990: DeVol D L; Rotwein P; Sadow J L; Novakofski J; Bechtel P J
Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth.
The American journal of physiology 1990;259(1 Pt 1):E89-95.
1990: Lajara R; Galgani J P; Dempsher D P; Bier D M; Rotwein P
Low prevalence of insulin-like growth factor-I gene mutations in human growth disorders.
The Journal of clinical endocrinology and metabolism 1990;70(3):687-92.
1990: Kajimoto Y; Rotwein P
Evolution of insulin-like growth factor I (IGF-I): structure and expression of an IGF-I precursor from Xenopus laevis.
Molecular endocrinology (Baltimore, Md.) 1990;4(2):217-26.
1990: Lauterio T J; Aravich P F; Rotwein P
Divergent effects of insulin on insulin-like growth factor-II gene expression in the rat hypothalamus.
Endocrinology 1990;126(1):392-8.
1989: Kajimoto Y; Rotwein P
Structure and expression of a chicken insulin-like growth factor I precursor.
Molecular endocrinology (Baltimore, Md.) 1989;3(12):1907-13.
1989: Godowski P J; Leung D W; Meacham L R; Galgani J P; Hellmiss R; Keret R; Rotwein P S; Parks J S; Laron Z; Wood W I
Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron-type dwarfism.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):8083-7.
1989: Lajara R; Rotwein P; Bortz J D; Hansen V A; Sadow J L; Betts C R; Rogers S A; Hammerman M R
Dual regulation of insulin-like growth factor I expression during renal hypertrophy.
The American journal of physiology 1989;257(2 Pt 2):F252-61.
1989: Tollefsen S E; Lajara R; McCusker R H; Clemmons D R; Rotwein P
Insulin-like growth factors (IGF) in muscle development. Expression of IGF-I, the IGF-I receptor, and an IGF binding protein during myoblast differentiation.
The Journal of biological chemistry 1989;264(23):13810-7.
1989: Hauft S M; Sweetser D A; Rotwein P S; Lajara R; Hoppe P C; Birkenmeier E H; Gordon J I
A transgenic mouse model that is useful for analyzing cellular and geographic differentiation of the intestine during fetal development.
The Journal of biological chemistry 1989;264(14):8419-29.
1989: Tollefsen S E; Sadow J L; Rotwein P
Coordinate expression of insulin-like growth factor II and its receptor during muscle differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(5):1543-7.
1989: Hennessy S W; Frazier B A; Kim D D; Deckwerth T L; Baumgartel D M; Rotwein P; Frazier W A
Complete thrombospondin mRNA sequence includes potential regulatory sites in the 3' untranslated region.
The Journal of cell biology 1989;108(2):729-36.
1989: Daughaday W H; Rotwein P
Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations.
Endocrine reviews 1989;10(1):68-91.
1988: Daughaday W H; Emanuele M A; Brooks M H; Barbato A L; Kapadia M; Rotwein P
Synthesis and secretion of insulin-like growth factor II by a leiomyosarcoma with associated hypoglycemia.
The New England journal of medicine 1988;319(22):1434-40.
1988: Turner J D; Rotwein P; Novakofski J; Bechtel P J
Induction of mRNA for IGF-I and -II during growth hormone-stimulated muscle hypertrophy.
The American journal of physiology 1988;255(4 Pt 1):E513-7.
1988: Bortz J D; Rotwein P; DeVol D; Bechtel P J; Hansen V A; Hammerman M R
Focal expression of insulin-like growth factor I in rat kidney collecting duct.
The Journal of cell biology 1988;107(2):811-9.
1988: O'Malley K L; Rotwein P
Human tyrosine hydroxylase and insulin genes are contiguous on chromosome 11.
Nucleic acids research 1988;16(10):4437-46.
1988: Rotwein P; Burgess S K; Milbrandt J D; Krause J E
Differential expression of insulin-like growth factor genes in rat central nervous system.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(1):265-9.
1987: Rotwein P; Pollock K M; Watson M; Milbrandt J D
Insulin-like growth factor gene expression during rat embryonic development.
Endocrinology 1987;121(6):2141-4.
1987: Shimatsu A; Rotwein P
Sequence of two rat insulin-like growth factor I mRNAs differing within the 5' untranslated region.
Nucleic acids research 1987;15(17):7196.
1987: Rotwein P; Folz R J; Gordon J I
Biosynthesis of human insulin-like growth factor I (IGF-I). The primary translation product of IGF-I mRNA contains an unusual 48-amino acid signal peptide.
The Journal of biological chemistry 1987;262(24):11807-12.
1987: Frazier W A; Dixit V M; Galvin N J; Rotwein P R
Structure of human thrombospondin: complete amino acid sequence derived from cDNA.
Seminars in thrombosis and hemostasis 1987;13(3):255-60.
1987: Shimatsu A; Rotwein P
Mosaic evolution of the insulin-like growth factors. Organization, sequence, and expression of the rat insulin-like growth factor I gene.
The Journal of biological chemistry 1987;262(16):7894-900.
1986: Rotwein P; Naylor S L; Chirgwin J M
Human insulin-related DNA sequences map to chromosomes 2 and 11.
Somatic cell and molecular genetics 1986;12(6):625-31.
1986: Rotwein P; Yokoyama S; Didier D K; Chirgwin J M
Genetic analysis of the hypervariable region flanking the human insulin gene.
American journal of human genetics 1986;39(3):291-9.
1986: Dixit V M; Hennessy S W; Grant G A; Rotwein P; Frazier W A
Characterization of a cDNA encoding the heparin and collagen binding domains of human thrombospondin.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(15):5449-53.
1986: Rotwein P; Pollock K M; Didier D K; Krivi G G
Organization and sequence of the human insulin-like growth factor I gene. Alternative RNA processing produces two insulin-like growth factor I precursor peptides.
The Journal of biological chemistry 1986;261(11):4828-32.
1986: Tieber V L; Abruzzini L F; Didier D K; Schwartz B D; Rotwein P
Complete characterization and sequence of an HLA class II DR beta chain cDNA from the DR5 haplotype.
The Journal of biological chemistry 1986;261(6):2738-42.
1986: Rotwein P
Two insulin-like growth factor I messenger RNAs are expressed in human liver.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(1):77-81.
1985: Elbein S; Rotwein P; Permutt M A; Bell G I; Sanz N; Karam J H
Lack of association of the polymorphic locus in the 5'-flanking region of the human insulin gene and diabetes in American blacks.
Diabetes 1985;34(5):433-9.
1985: Permutt M A; Rotwein P; Andreone T; Ward W K; Porte D
Islet beta-cell function and polymorphism in the 5'-flanking region of the human insulin gene.
Diabetes 1985;34(4):311-4.
1985: Andreone T; Fajans S; Rotwein P; Skolnick M; Permutt M A
Insulin gene analysis in a family with maturity-onset diabetes of the young.
Diabetes 1985;34(2):108-14.
1985: Permutt M A; Andreone T; Chirgwin J; Elbein S; Rotwein P; Orland M
The genetics of type I and type II diabetes: analysis by recombinant DNA methodology.
Advances in experimental medicine and biology 1985;189():89-106.
1984: Knowler W C; Pettitt D J; Vasquez B; Rotwein P S; Andreone T L; Permutt M A
Polymorphism in the 5' flanking region of the human insulin gene. Relationships with noninsulin-dependent diabetes mellitus, glucose and insulin concentrations, and diabetes treatment in the Pima Indians.
The Journal of clinical investigation 1984;74(6):2129-35.
1984: Permutt M A; Chirgwin J; Rotwein P; Giddings S
Insulin gene structure and function: a review of studies using recombinant DNA methodology.
Diabetes care 1984;7(4):386-94.
1984: Chirgwin J M; Schaefer I M; Rotwein P S; Piccini N; Gross K W; Naylor S L
Human renin gene is on chromosome 1.
Somatic cell and molecular genetics 1984;10(4):415-21.
1983: Permutt M A; Rotwein P
Analysis of the insulin gene in noninsulin-dependent diabetes.
The American journal of medicine 1983;75(5B):1-7.
1983: Giddings S J; Rotwein P; Chirgwin J M; Scharp D; Permutt M A
Analysis of insulin gene expression in human pancreas.
Diabetes 1983;32(8):777-80.
1983: Kakita K; Giddings S J; Rotwein P S; Permutt M A
Insulin gene expression in the developing rat pancreas.
Diabetes 1983;32(8):691-6.
1983: Rotwein P S; Chirgwin J; Province M; Knowler W C; Pettitt D J; Cordell B; Goodman H M; Permutt M A
Polymorphism in the 5' flanking region of the human insulin gene: a genetic marker for non-insulin-dependent diabetes.
The New England journal of medicine 1983;308(2):65-71.
1982: Rotwein P S; Giddings S J; Permutt M A
Diagnosis and management of hypoglycemic disorders in adults.
Special topics in endocrinology and metabolism 1982;3():87-115.
1981: Permutt A; Chirgwin J; Giddings S; Kakita K; Rotwein P
Insulin biosynthesis and diabetes mellitus.
Clinical biochemistry 1981;14(5):230-6.
1981: Rotwein P; Chyn R; Chirgwin J; Cordell B; Goodman H M; Permut M A
Polymorphism in the 5'-flanking region of the human insulin gene and its possible relation to type 2 diabetes.
Science (New York, N.Y.) 1981;213(4512):1117-20.

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