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John Routsias

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TOP 3
Aristotelis Tsiakalos; Athanasios G Tzioufas; Theodore Kordossis; Haralampos M Moutsopoulos; John G Routsias; Nikolaos V Sipsas
Fine epitope specificity of anti-erythropoietin antibodies reveals molecular mimicry with HIV-1 p17 protein: a pathogenetic mechanism for HIV-1-related anemia.
Helena Maltezou; Stefanos Mantagos; Antonios Maragos; Maria Mavrouli; Simeon Metallidis; Pavlos Nikolaidis; Emmanuel Roilides; John G Routsias; Nicholas Spanakis; Anastasia Tedoma; Maria Theodoridou; Yiannis Bassiakos; Panagiotis Katerelos; Aspasia Katragkou; George Koratzanis; Athanasia Lourida; Athanassios Tsakris
Seroepidemiological study of pandemic influenza H1N1 following the 2009-2010 wave in Greece.
John G Routsias; Jill P Buyon; Robert Clancy; Deborah M Friedman; Nikolaos C Kyriakidis; Carolina Llanos; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Association of the idiotype:antiidiotype antibody ratio with the efficacy of intravenous immunoglobulin treatment for the prevention of recurrent autoimmune-associated congenital heart block.

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All Publications

2011: Aristotelis Tsiakalos; Athanasios G Tzioufas; Theodore Kordossis; Haralampos M Moutsopoulos; John G Routsias; Nikolaos V Sipsas
Fine epitope specificity of anti-erythropoietin antibodies reveals molecular mimicry with HIV-1 p17 protein: a pathogenetic mechanism for HIV-1-related anemia.
The Journal of infectious diseases 2011;204(6):902-11.
2011: Helena Maltezou; Stefanos Mantagos; Antonios Maragos; Maria Mavrouli; Simeon Metallidis; Pavlos Nikolaidis; Emmanuel Roilides; John G Routsias; Nicholas Spanakis; Anastasia Tedoma; Maria Theodoridou; Yiannis Bassiakos; Panagiotis Katerelos; Aspasia Katragkou; George Koratzanis; Athanasia Lourida; Athanassios Tsakris
Seroepidemiological study of pandemic influenza H1N1 following the 2009-2010 wave in Greece.
Vaccine 2011;29(38):6664-9.
2011: John G Routsias; Jill P Buyon; Robert Clancy; Deborah M Friedman; Nikolaos C Kyriakidis; Carolina Llanos; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Association of the idiotype:antiidiotype antibody ratio with the efficacy of intravenous immunoglobulin treatment for the prevention of recurrent autoimmune-associated congenital heart block.
Arthritis and rheumatism 2011;63(9):2783-9.
2011: John G Routsias; Georgios Charalampakis; Andreas Goules; John D Goules; Dimitrios Pikazis
Autopathogenic correlation of periodontitis and rheumatoid arthritis.
Rheumatology (Oxford, England) 2011;50(7):1189-93.
2011: Pantelis P Pavlakis; John G Routsias; Eleftherios Stamboulis; Socrates J Tzartos; Athanasios G Tzioufas; Haralampos Alexopoulos; Michael L Kosmidis; Haralampos M Moutsopoulos; Marinos C Dalakas
Peripheral neuropathies in Sjogren syndrome: a new reappraisal.
Journal of neurology, neurosurgery, and psychiatry 2011;82(7):798-802.
2011: Maria D Mavrouli; John G Routsias; Nicholas Spanakis; Helena C Maltezou; Athanassios Tsakris
Estimation of seroprevalence of the pandemic H1N1 2009 influenza virus using a novel virus-free ELISA assay for the detection of specific antibodies.
Viral immunology 2011;24(3):221-6.
2011: E I Kampylafka; John G Routsias; H Alexopoulos; Marinos C Dalakas; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Fine specificity of antibodies against AQP4: epitope mapping reveals intracellular epitopes.
Journal of autoimmunity 2011;36(3-4):221-7.
2011: Christos I Sinapis; John G Routsias; Angelos I Sinapis; Dimitrios I Sinapis; George D Agrogiannis; Alkistis Pantopoulou; Stamatis E Theocharis; Stefanos Baltatzis; Efstratios Patsouris; Despoina Perrea
Pharmacokinetics of intravitreal bevacizumab (Avastin®) in rabbits.
Clinical ophthalmology (Auckland, N.Z.) 2011;5():697-704.
2010: John G Routsias; Athanasios G Tzioufas
B-cell epitopes of the intracellular autoantigens Ro/SSA and La/SSB: tools to study the regulation of the autoimmune response.
Journal of autoimmunity 2010;35(3):256-64.
2010: Panayiotis G Vlachoyiannopoulos; John G Routsias
A novel mechanism of thrombosis in antiphospholipid antibody syndrome.
Journal of autoimmunity 2010;35(3):248-55.
2010: John G Routsias; Athanasios G Tzioufas
Autoimmune response and target autoantigens in Sjogren's syndrome.
European journal of clinical investigation 2010;40(11):1026-36.
2010: John G Routsias; Panagiotis Karagounis; Georgeta Parvulesku; Nicholas J Legakis; Athanassios Tsakris
In vitro bactericidal activity of human beta-defensin 2 against nosocomial strains.
Peptides 2010;31(9):1654-60.
2010: Athanasios G Tzioufas; John G Routsias
Idiotype, anti-idiotype network of autoantibodies: pathogenetic considerations and clinical application.
Autoimmunity reviews 2010;9(9):631-3.
2010: Marina P Sikara; John G Routsias; Martina Samiotaki; George Panayotou; Haralampos M Moutsopoulos; Panayiotis G Vlachoyiannopoulos
{beta}2 Glycoprotein I ({beta}2GPI) binds platelet factor 4 (PF4): implications for the pathogenesis of antiphospholipid syndrome.
Blood 2010;115(3):713-23.
2010: John G Routsias; Nikolaos Kyriakidis; Michael Latreille; Athanasios G Tzioufas
RNA recognition motif (RRM) of La/SSB: the bridge for interparticle spreading of autoimmune response to U1-RNP.
Molecular medicine (Cambridge, Mass.) 2010;16(1-2):19-26.
2009: Efi Bourazopoulou; Efstathia K Kapsogeorgou; John G Routsias; Menelaos N Manoussakis; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Functional expression of the alpha 2-macroglobulin receptor CD91 in salivary gland epithelial cells.
Journal of autoimmunity 2009;33(2):141-6.
2007: John G Routsias; Athanasios G Tzioufas
Sjögren's syndrome--study of autoantigens and autoantibodies.
Clinical reviews in allergy & immunology 2007;32(3):238-51.
2007: M D Mavrouli; Nicholas Spanakis; S Levidiotou; C Politi; S Alexiou; Parthenopi M Tseliou; M Hatzitaki; K Foundouli; Athanassios Tsakris; Nicholas J Legakis; John G Routsias
Serologic prevalence of coxsackievirus group B in Greece.
Viral immunology 2007;20(1):11-8.
2007: Eleni A Stea; John G Routsias; Martina Samiotaki; George Panayotou; E Papalambros; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Analysis of parotid glands of primary Sjögren's syndrome patients using proteomic technology reveals altered autoantigen composition and novel antigenic targets.
Clinical and experimental immunology 2007;147(1):81-9.
2006: John G Routsias; Athanasios G Tzioufas
The role of chaperone proteins in autoimmunity.
Annals of the New York Academy of Sciences 2006;1088():52-64.
2006: Apostolis TERZOGLOU; John G Routsias; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Post-translational modifications of the major linear epitope 169-190aa of Ro60 kDa autoantigen alter the autoantibody binding.
Clinical and experimental immunology 2006;146(1):60-5.
2006: Eleni A Stea; John G Routsias; Robert M Clancy; Jill P Buyon; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Anti-La/SSB antiidiotypic antibodies in maternal serum: a marker of low risk for neonatal lupus in an offspring.
Arthritis and rheumatism 2006;54(7):2228-34.
2006: Panayiotis D Ziakas; John G Routsias; Stavroula Giannouli; Anna Tasidou; Athanasios G Tzioufas; Michael Voulgarelis
Suspects in the tale of lupus-associated thrombocytopenia.
Clinical and experimental immunology 2006;145(1):71-80.
2006: Apostolis TERZOGLOU; John G Routsias; Stratis Avrameas; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Preferential recognition of the phosphorylated major linear B-cell epitope of La/SSB 349-368 aa by anti-La/SSB autoantibodies from patients with systemic autoimmune diseases.
Clinical and experimental immunology 2006;144(3):432-9.
2006: Andreas Goules; Athanasios G Tzioufas; Menelaos N Manousakis; Kyriakos A Kirou; Mary Crow; John G Routsias
Elevated levels of soluble CD40 ligand (sCD40L) in serum of patients with systemic autoimmune diseases.
Journal of autoimmunity 2006;26(3):165-71.
2006: John G Routsias; Panayiotis G Vlachoyiannopoulos; Athanasios G Tzioufas
Autoantibodies to intracellular autoantigens and their B-cell epitopes: molecular probes to study the autoimmune response.
Critical reviews in clinical laboratory sciences 2006;43(3):203-48.
2005: Evgenia Touloupi; John G Routsias; Athanasios G Tzioufas
Cross-recognition between histones and La/SSB may account for anti-DNA reactivity in SLE patients.
Clinical and experimental immunology 2005;142(1):172-9.
2005: Evangelia Stathopoulou; John G Routsias; Eleni A Stea; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Cross-reaction between antibodies to the major epitope of Ro60 kD autoantigen and a homologous peptide of Coxsackie virus 2B protein.
Clinical and experimental immunology 2005;141(1):148-54.
2004: Panayiotis G Vlachoyiannopoulos; Clio P Mavragani; Efi Bourazopoulou; Anthi V Balitsari; John G Routsias
Anti-CD40 antibodies in antiphospholipid syndrome and systemic lupus erythematosus.
Thrombosis and haemostasis 2004;92(6):1303-11.
2004: John G Routsias; Aggeliki Kosmopoulou; Athina Makri; Eugenia Panou-Pomonis; Constantinos Sakarellos; Maria Sakarellos-Daitsiotis; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Zinc ion dependent B-cell epitope, associated with primary Sjogren's syndrome, resides within the putative zinc finger domain of Ro60kD autoantigen: physical and immunologic properties.
Journal of medicinal chemistry 2004;47(17):4327-34.
2004: John G Routsias; Athanasios G Tzioufas
Origin, antigenic specificity and regulation of autoantibodies targeting Ro/La RNP.
Autoimmunity reviews 2004;3 Suppl 1():S63-5.
2004: Meropi Kontogianni; Urania Dafni; John G Routsias; Fotini N Skopouli
Blood leptin and adiponectin as possible mediators of the relation between fat mass and BMD in perimenopausal women.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(4):546-51.
2004: M G Papamattheou; John G Routsias; Evdokia Karagouni; Constantinos Sakarellos; Maria Sakarellos-Daitsiotis; Haralampos M Moutsopoulos; Athanasios G Tzioufas; Eleni Dotsika
T cell help is required to induce idiotypic-anti-idiotypic autoantibody network after immunization with complementary epitope 289-308aa of La/SSB autoantigen in non-autoimmune mice.
Clinical and experimental immunology 2004;135(3):416-26.
2004: John G Routsias; Athanasios G Tzioufas; Haralampos M Moutsopoulos
The clinical value of intracellular autoantigens B-cell epitopes in systemic rheumatic diseases.
Clinica chimica acta; international journal of clinical chemistry 2004;340(1-2):1-25.
2003: E V Staikou; John G Routsias; A A Makri; Apostolis TERZOGLOU; Maria Sakarellos-Daitsiotis; Constantinos Sakarellos; George Panayotou; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Calreticulin binds preferentially with B cell linear epitopes of Ro60 kD autoantigen, enhancing recognition by anti-Ro60 kD autoantibodies.
Clinical and experimental immunology 2003;134(1):143-50.
2003: Apostolis TERZOGLOU; John G Routsias; Constantinos Sakarellos; Maria Sakarellos-Daitsiotis; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Linear epitopes of two different autoantigens-La/SSB and myelin basic protein--with a high degree of molecular similarity, cause different humoral immune responses.
Journal of autoimmunity 2003;21(1):47-57.
2003: John G Routsias; Eleni Dotsika; Evgenia Touloupi; Maria Papamattheou; Constantinos Sakarellos; Maria Sakarellos-Daitsiotis; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Idiotype-anti-idiotype circuit in non-autoimmune mice after immunization with the epitope and complementary epitope 289-308aa of La/SSB: implications for the maintenance and perpetuation of the anti-La/SSB response.
Journal of autoimmunity 2003;21(1):17-26.
2002: John G Routsias; Evgenia Touloupi; Eleni Dotsika; Avrilia Moulia; Vassilios Tsikaris; Constantinos Sakarellos; Maria Sakarellos-Daitsiotis; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Unmasking the anti-La/SSB response in sera from patients with Sjogren's syndrome by specific blocking of anti-idiotypic antibodies to La/SSB antigenic determinants.
Molecular medicine (Cambridge, Mass.) 2002;8(6):293-305.
2000: Niki M Moutsopoulos; John G Routsias; Panayiotis G Vlachoyiannopoulos; Athanasios G Tzioufas; Haralampos M Moutsopoulos
B-cell epitopes of intracellular autoantigens: myth and reality.
Molecular medicine (Cambridge, Mass.) 2000;6(3):141-51.
1998: John G Routsias; Maria Sakarellos-Daitsiotis; Vassilios Tsikaris; Constantinos Sakarellos; Haralampos M Moutsopoulos; Athanasios G Tzioufas
Structural, molecular and immunological properties of linear B-cell epitopes of Ro60KD autoantigen.
Scandinavian journal of immunology 1998;47(3):280-7.
1997: Athanasios G Tzioufas; EE Yiannaki; Maria Sakarellos-Daitsiotis; John G Routsias; Constantinos Sakarellos; Haralampos M Moutsopoulos
Fine specificity of autoantibodies to La/SSB: epitope mapping, and characterization.
Clinical and experimental immunology 1997;108(2):191-8.
1996: K Paliakasis; John G Routsias; K Petratos; Christos Ouzounis; Michael Kokkinidis; George K Papadopoulos
Novel structural features of the human histocompatibility molecules HLA-DQ as revealed by modeling based on the published structure of the related molecule HLA-DR.
Journal of structural biology 1996;117(2):145-63.
1996: John G Routsias; Athanasios G Tzioufas; Maria Sakarellos-Daitsiotis; Constantinos Sakarellos; Haralampos M Moutsopoulos
Epitope mapping of the Ro/SSA60KD autoantigen reveals disease-specific antibody-binding profiles.
European journal of clinical investigation 1996;26(6):514-21.
1995: John G Routsias; George K Papadopoulos
Polymorphic structural features of modelled HLA-DQ molecules segregate according to susceptibility or resistance to IDDM.
Diabetologia 1995;38(11):1251-61.
1994: John G Routsias; Maria Sakarellos-Daitsiotis; E Detsikas; Athanasios G Tzioufas; Constantinos Sakarellos; Haralampos M Moutsopoulos
Antibodies to EYRKK vesicular stomatitis virus-related peptide account only for a minority of anti-Ro60kD antibodies.
Clinical and experimental immunology 1994;98(3):414-8.
1993: John G Routsias; Athanasios G Tzioufas; Maria Sakarellos-Daitsiotis; Constantinos Sakarellos; Haralampos M Moutsopoulos
Calreticulin synthetic peptide analogues: anti-peptide antibodies in autoimmune rheumatic diseases.
Clinical and experimental immunology 1993;91(3):437-41.