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Namita Roy-Chowdhury

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Chemicals & Drugs

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Hongchao Zhou; Yesim Avsar; Yong Chen; Jianqiang Ding; Xinyuan Dong; Ira J Fox; Rafi Kabarriti; Laibin Liu; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; Xia Wang; Chandan Guha
Single liver lobe repopulation with wildtype hepatocytes using regional hepatic irradiation cures jaundice in Gunn rats.
Jianqiang Ding; Govardhana R Yannam; Namita Roy-Chowdhury; Tunda Hidvegi; Hesham Basma; Stephen I Rennard; Ronald J Wong; Yesim Avsar; Chandan Guha; David H Perlmutter; Ira J Fox; Jayanta Roy-Chowdhury
Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes.
Xia Wang; Debi P Sarkar; Prashant Mani; Clifford J Steer; Yong Chen; Chandan Guha; Voshavar Chandrasekhar; Arabinda Chaudhuri; Namita Roy-Chowdhury; Betsy T Kren; Jayanta Roy-Chowdhury
Long-term reduction of jaundice in Gunn rats by nonviral liver-targeted delivery of Sleeping Beauty transposon.

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2012: Hongchao Zhou; Yesim Avsar; Yong Chen; Jianqiang Ding; Xinyuan Dong; Ira J Fox; Rafi Kabarriti; Laibin Liu; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; Xia Wang; Chandan Guha
Single liver lobe repopulation with wildtype hepatocytes using regional hepatic irradiation cures jaundice in Gunn rats.
PloS one 2012;7(10):e46775.
2011: Jianqiang Ding; Govardhana R Yannam; Namita Roy-Chowdhury; Tunda Hidvegi; Hesham Basma; Stephen I Rennard; Ronald J Wong; Yesim Avsar; Chandan Guha; David H Perlmutter; Ira J Fox; Jayanta Roy-Chowdhury
Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes.
The Journal of clinical investigation 2011;121(5):1930-4.
2009: Xia Wang; Debi P Sarkar; Prashant Mani; Clifford J Steer; Yong Chen; Chandan Guha; Voshavar Chandrasekhar; Arabinda Chaudhuri; Namita Roy-Chowdhury; Betsy T Kren; Jayanta Roy-Chowdhury
Long-term reduction of jaundice in Gunn rats by nonviral liver-targeted delivery of Sleeping Beauty transposon.
Hepatology (Baltimore, Md.) 2009;50(3):815-24.
2009: Shmuel Zangen; Devorah Kidron; Terri Gelbart; Namita Roy-Chowdhury; Xia Wang; Michael Kaplan
Fatal kernicterus in a girl deficient in glucose-6-phosphate dehydrogenase: a paradigm of synergistic heterozygosity.
The Journal of pediatrics 2009;154(4):616-9.
2009: Payel Bhanja; Subhrajit Saha; Rafi Kabarriti; Laibin Liu; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Rani S Sellers; Alan Alfieri; Chandan Guha
Protective role of R-spondin1, an intestinal stem cell growth factor, against radiation-induced gastrointestinal syndrome in mice.
PloS one 2009;4(11):e8014.
2009: Xia Wang; Prashant Mani; Debi P Sarkar; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Ex vivo gene transfer into hepatocytes.
Methods in molecular biology (Clifton, N.J.) 2009;481():117-40.
2009: Kosho Yamanouchi; Hongchao Zhou; Namita Roy-Chowdhury; Frank Macaluso; Liping Liu; Toshiyuki Yamamoto; Govardhana Rao Yannam; Charles Enke; Timothy D Solberg; Anthony B Adelson; Jeffrey L Platt; Ira J Fox; Jayanta Roy-Chowdhury; Chandan Guha
Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation.
Hepatology (Baltimore, Md.) 2009;49(1):258-67.
2008: Yujo Kawashita; Chandan Guha; Rituparna Moitra; Xia Wang; Ira J Fox; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
Hepatic repopulation with stably transduced conditionally immortalized hepatocytes in the Gunn rat.
Journal of hepatology 2008;49(1):99-106.
2008: Jinlan Jiang; Eduardo C Salido; Chandan Guha; Xia Wang; Rituparna Moitra; Laibin Liu; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
Correction of hyperoxaluria by liver repopulation with hepatocytes in a mouse model of primary hyperoxaluria type-1.
Transplantation 2008;85(9):1253-60.
2007: Elena V Mashalova; Chandan Guha; Namita Roy-Chowdhury; Laibin Liu; Ira J Fox; Jayanta Roy-Chowdhury; Marshall S Horwitz
Prevention of hepatocyte allograft rejection in rats by transferring adenoviral early region 3 genes into donor cells.
Hepatology (Baltimore, Md.) 2007;45(3):755-66.
2006: Eduardo Salido; Xiao M Li; Yang Lu; Xia Wang; Alfredo Santana; Namita Roy-Chowdhury; Armando Torres; Lawrence J Shapiro; Jayanta Roy-Chowdhury
Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18249-54.
2006: Charles S Landis; Kosho Yamanouchi; Hongchao Zhou; Sankar Mohan; Namita Roy-Chowdhury; David A Shafritz; Alan Koretsky; Jayanta Roy-Chowdhury; Hoby P Hetherington; Chandan Guha
Noninvasive evaluation of liver repopulation by transplanted hepatocytes using 31P MRS imaging in mice.
Hepatology (Baltimore, Md.) 2006;44(5):1250-8.
2006: S Joseph Kim; G V Ramesh Prasad; Michael Huang; Michelle M Nash; Olusegun Famure; Joseph Park; Mary Ann Thenganatt; Namita Roy-Chowdhury; Edward H Cole; Stanley S A Fenton; Daniel C Cattran; Jeffrey S Zaltzman; Carl J Cardella
A comparison of the effects of C2-cyclosporine and C0-tacrolimus on renal function and cardiovascular risk factors in kidney transplant recipients.
Transplantation 2006;82(7):924-30.
2005: Siddhartha S Ghosh; Yang Lu; Sung W Lee; Xia Wang; Chandan Guha; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
Role of cysteine residues in the function of human UDP glucuronosyltransferase isoform 1A1 (UGT1A1).
The Biochemical journal 2005;392(Pt 3):685-92.
2005: Chandan Guha; Kosho Yamanouchi; Jinlan Jiang; Xia Wang; Namita Roy-Chowdhury; Alfredo Santana; Lawrence J Shapiro; Eduardo Salido; Jayanta Roy-Chowdhury
Feasibility of hepatocyte transplantation-based therapies for primary hyperoxalurias.
American journal of nephrology 2005;25(2):161-70.
2005: Chandan Guha; Sunhee C Lee; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Cell culture models and animal models of viral hepatitis. Part II: hepatitis C.
Lab animal 2005;34(2):39-47.
2004: Chandan Guha; Sankar Mohan; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Cell culture and animal models of viral hepatitis. Part I: hepatitis B.
Lab animal 2004;33(7):37-46.
2004: Sung-W Lee; Xia Wang; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Hepatocyte transplantation: state of the art and strategies for overcoming existing hurdles.
Annals of hepatology 2004;3(2):48-53.
2004: Peter G Wells; Peter I Mackenzie; Jayanta Roy-Chowdhury; Chantal Guillemette; Philip A Gregory; Yuji Ishii; Antony J Hansen; Fay K Kessler; Perry M Kim; Namita Roy-Chowdhury; Joseph K Ritter
Glucuronidation and the UDP-glucuronosyltransferases in health and disease.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(3):281-90.
2003: Jayanta Roy-Chowdhury; Joseph Locker; Namita Roy-Chowdhury
Nuclear receptors orchestrate detoxification pathways.
Developmental cell 2003;4(5):607-8.
2003: M Takahashi; Niloy J Deb; Yujo Kawashita; Sung W Lee; J Furgueil; T Okuyama; Namita Roy-Chowdhury; Bhadrasain Vikram; Jayanta Roy-Chowdhury; Chandan Guha
A novel strategy for in vivo expansion of transplanted hepatocytes using preparative hepatic irradiation and FasL-induced hepatocellular apoptosis.
Gene therapy 2003;10(4):304-13.
2003: Chandan Guha; Shalin J Shah; Siddhartha S Ghosh; Sung W Lee; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Molecular therapies for viral hepatitis.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 2003;17(2):81-91.
2002: Betsy T Kren; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Clifford J Steer
Gene therapy as an alternative to liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2002;8(12):1089-108.
2002: Chandan Guha; Bhupesh Parashar; Niloy J Deb; Madhur Garg; Giridhar R Gorla; Anupam Singh; Namita Roy-Chowdhury; Bhadrasain Vikram; Jayanta Roy-Chowdhury
Normal hepatocytes correct serum bilirubin after repopulation of Gunn rat liver subjected to irradiation/partial resection.
Hepatology (Baltimore, Md.) 2002;36(2):354-62.
2002: NR Thummala; Siddhartha S Ghosh; Sung W Lee; Bhoompally Reddy; Anne Davidson; Marshall S Horwitz; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome.
Gene therapy 2002;9(15):981-90.
2002: Betsy T Kren; Z Chen; R Felsheim; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Clifford J Steer
Modification of hepatic genomic DNA using RNA/DNA oligonucleotides.
Gene therapy 2002;9(11):686-90.
2002: Baljit S Sappal; Siddhartha S Ghosh; Benjamin Shneider; Ajit Kadakol; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
A novel intronic mutation results in the use of a cryptic splice acceptor site within the coding region of UGT1A1, causing Crigler-Najjar syndrome type 1.
Molecular genetics and metabolism 2002;75(2):134-42.
2002: Namita Roy-Chowdhury; Bisram Deocharan; H R Bejjanki; Jayanta Roy-Chowdhury; C Koliopoulos; S Petmezaki; T Valaes
Presence of the genetic marker for Gilbert syndrome is associated with increased level and duration of neonatal jaundice.
Acta paediatrica (Oslo, Norway : 1992) 2002;91(1):100-1.
2002: Betsy T Kren; Paramita Bandyopadhyay; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Clifford J Steer
Oligonucleotide-mediated site-directed gene repair.
Methods in enzymology 2002;346():14-35.
2001: Namita Roy-Chowdhury; Ajit Kadakol; Baljit S Sappal; NR Thummala; Siddhartha S Ghosh; Sung W Lee; Jayanta Roy-Chowdhury
Gene therapy for inherited hyperbilirubinemias.
Journal of perinatology : official journal of the California Perinatal Association 2001;21 Suppl 1():S114-8; discussion S125-7.
2001: Siddhartha S Ghosh; Baljit S Sappal; Ganjam V Kalpana; Sung W Lee; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
Homodimerization of human bilirubin-uridine-diphosphoglucuronate glucuronosyltransferase-1 (UGT1A1) and its functional implications.
The Journal of biological chemistry 2001;276(45):42108-15.
2001: Chandan Guha; Niloy J Deb; Baljit S Sappal; Siddhartha S Ghosh; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Amplification of engrafted hepatocytes by preparative manipulation of the host liver.
Artificial organs 2001;25(7):522-8.
2001: Ajit Kadakol; Baljit S Sappal; Siddhartha S Ghosh; M Lowenheim; A Chowdhury; S Chowdhury; A Santra; I M Arias; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
Interaction of coding region mutations and the Gilbert-type promoter abnormality of the UGT1A1 gene causes moderate degrees of unconjugated hyperbilirubinaemia and may lead to neonatal kernicterus.
Journal of medical genetics 2001;38(4):244-9.
2001: Chandan Guha; Bhupesh Parashar; Niloy J Deb; Anand K Sharma; Giridhar R Gorla; Alan Alfieri; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Bhadrasain Vikram
Liver irradiation: a potential preparative regimen for hepatocyte transplantation.
International journal of radiation oncology, biology, physics 2001;49(2):451-7.
2001: Chandan Guha; Namita Roy-Chowdhury; H Jauregui; Jayanta Roy-Chowdhury
Hepatocyte-based gene therapy.
Journal of hepato-biliary-pancreatic surgery 2001;8(1):51-7.
2000: BV Sauter; Bhupesh Parashar; Namita Roy-Chowdhury; Ajit Kadakol; Yaron Ilan; H Singh; J Milano; David S Strayer; Jayanta Roy-Chowdhury
A replication-deficient rSV40 mediates liver-directed gene transfer and a long-term amelioration of jaundice in gunn rats.
Gastroenterology 2000;119(5):1348-57.
2000: Ajit Kadakol; Siddhartha S Ghosh; Baljit S Sappal; G Sharma; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
Genetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyltransferase (UGT1A1) causing Crigler-Najjar and Gilbert syndromes: correlation of genotype to phenotype.
Human mutation 2000;16(4):297-306.
2000: H Minami; K Tada; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Morikazu Onji
Enhancement of retrovirus-mediated gene transfer to rat liver in vivo by infusion of hepatocyte growth factor and triiodothyronine.
Journal of hepatology 2000;33(2):183-8.
2000: Chandan Guha; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Reversibly immortalized human hepatocytes: an eternal fountain of liver support?
Hepatology (Baltimore, Md.) 2000;32(2):440-1.
2000: Chandan Guha; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Recombinant adenoassociated virus in cancer gene therapy.
Journal of hepatology 2000;32(6):1031-4.
2000: Yaron Ilan; Sarah Zangen; S Ben-Horin; Judith Diment; BV Sauter; Elazar Rabbani; Dean Engelhardt; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Eran Goldin
Treatment of experimental colitis by oral tolerance induction: a central role for suppressor lymphocytes.
The American journal of gastroenterology 2000;95(4):966-73.
2000: Arnon Nagler; Mark Pines; U Abadi; O Pappo; Michael Zeira; Elazar Rabbani; D Engelhardt; Meir Ohana; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Yaron Ilan
Oral tolerization ameliorates liver disorders associated with chronic graft versus host disease in mice.
Hepatology (Baltimore, Md.) 2000;31(3):641-8.
2000: Siddhartha S Ghosh; M Takahashi; NR Thummala; Bhupesh Parashar; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Liver-directed gene therapy: promises, problems and prospects at the turn of the century.
Journal of hepatology 2000;32(1 Suppl):238-52.
2000: J J Brown; Bhupesh Parashar; H Moshage; Kathryn Tanaka; D Engelhardt; Elazar Rabbani; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
A long-term hepatitis B viremia model generated by transplanting nontumorigenic immortalized human hepatocytes in Rag-2-deficient mice.
Hepatology (Baltimore, Md.) 2000;31(1):173-81.
1999: Chandan Guha; Anand K Sharma; Sanjeev Gupta; Alan Alfieri; Giridhar R Gorla; S Gagandeep; Rana P Sokhi; Namita Roy-Chowdhury; Kathryn Tanaka; Bhadrasain Vikram; Jayanta Roy-Chowdhury
Amelioration of radiation-induced liver damage in partially hepatectomized rats by hepatocyte transplantation.
Cancer research 1999;59(23):5871-4.
1999: Betsy T Kren; Bhupesh Parashar; Paramita Bandyopadhyay; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Clifford J Steer
Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(18):10349-54.
1999: Y Ilan; H Saito; NR Thummala; Namita Roy-Chowdhury
Adenovirus-mediated gene therapy of liver diseases.
Seminars in liver disease 1999;19(1):49-59.
1998: K Tada; Namita Roy-Chowdhury; Vinayaka R Prasad; B H Kim; P Manchikalapudi; Ira J Fox; P van Duijvendijk; Piter J Bosma; Jayanta Roy-Chowdhury
Long-term amelioration of bilirubin glucuronidation defect in Gunn rats by transplanting genetically modified immortalized autologous hepatocytes.
Cell transplantation 1998;7(6):607-16.
1998: Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; Stephen C Strom; Stuart S Kaufman; Simon Horslen; Ira J Fox
Human hepatocyte transplantation: gene therapy and more?
Pediatrics 1998;102(3 Pt 1):647-8.
1998: Ira J Fox; Jayanta Roy-Chowdhury; Stuart S Kaufman; Timothy C Goertzen; Namita Roy-Chowdhury; Phyllis I Warkentin; K Dorko; BV Sauter; Stephen C Strom
Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation.
The New England journal of medicine 1998;338(20):1422-6.
1998: Yaron Ilan; BV Sauter; Namita Roy-Chowdhury; B V Reddy; NR Thummala; G Droguett; Anne Davidson; M Ott; Marshall S Horwitz; Jayanta Roy-Chowdhury
Oral tolerization to adenoviral proteins permits repeated adenovirus-mediated gene therapy in rats with pre-existing immunity to adenoviruses.
Hepatology (Baltimore, Md.) 1998;27(5):1368-76.
1998: S Gantla; Conny T Bakker; Bisram Deocharan; NR Thummala; J Zweiner; M Sinaasappel; Jayanta Roy-Chowdhury; Piter J Bosma; Namita Roy-Chowdhury
Splice-site mutations: a novel genetic mechanism of Crigler-Najjar syndrome type 1.
American journal of human genetics 1998;62(3):585-92.
1998: K Tada; Namita Roy-Chowdhury; David Neufeld; Piter J Bosma; M Heard; Vinayaka R Prasad; Jayanta Roy-Chowdhury
Long-term reduction of serum bilirubin levels in Gunn rats by retroviral gene transfer in vivo.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1998;4(1):78-88.
1997: P Attavar; Lalbachan Budhai; B H Kim; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Anne Davidson
Mechanisms of intrathymic tolerance induction to isolated rat hepatocyte allografts.
Hepatology (Baltimore, Md.) 1997;26(5):1287-95.
1997: Yaron Ilan; V K Jona; K Sengupta; Anne Davidson; Marshall S Horwitz; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Transient immunosuppression with FK506 permits long-term expression of therapeutic genes introduced into the liver using recombinant adenoviruses in the rat.
Hepatology (Baltimore, Md.) 1997;26(4):949-56.
1997: Yaron Ilan; Namita Roy-Chowdhury; R Prakash; V Jona; P Attavar; Chandan Guha; K Tada; Jayanta Roy-Chowdhury
Massive repopulation of rat liver by transplantation of hepatocytes into specific lobes of the liver and ligation of portal vein branches to other lobes.
Transplantation 1997;64(1):8-13.
1997: J Nakamura; T Okamoto; I K Schumacher; I Tabei; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Ira J Fox
Treatment of surgically induced acute liver failure by transplantation of conditionally immortalized hepatocytes.
Transplantation 1997;63(11):1541-7.
1997: Naga Chalasani; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Thomas D Boyer
Kernicterus in an adult who is heterozygous for Crigler-Najjar syndrome and homozygous for Gilbert-type genetic defect.
Gastroenterology 1997;112(6):2099-103.
1997: Yaron Ilan; G Droguett; Namita Roy-Chowdhury; Y Li; K Sengupta; NR Thummala; Anne Davidson; Jayanta Roy-Chowdhury; Marshall S Horwitz
Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2587-92.
1997: Yaron Ilan; R Prakash; Anne Davidson; G Droguett; Marshall S Horwitz; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Oral tolerization to adenoviral antigens permits long-term gene expression using recombinant adenoviral vectors.
The Journal of clinical investigation 1997;99(5):1098-106.
1997: Jurgen Seppen; K Tada; Roelof Ottenhoff; K Sengupta; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Piter J Bosma; Ronald P J Oude Elferink
Transplantation of Gunn rats with autologous fibroblasts expressing bilirubin UDP-glucuronosyltransferase: correction of genetic deficiency and tumor formation.
Human gene therapy 1997;8(1):27-36.
1996: Yaron Ilan; P Attavar; M Takahashi; Anne Davidson; M S Horwitz; J Guida; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Induction of central tolerance by intrathymic inoculation of adenoviral antigens into the host thymus permits long-term gene therapy in Gunn rats.
The Journal of clinical investigation 1996;98(11):2640-7.
1996: M Takahashi; Yaron Ilan; Namita Roy-Chowdhury; J Guida; M Horwitz; Jayanta Roy-Chowdhury
Long term correction of bilirubin-UDP-glucuronosyltransferase deficiency in Gunn rats by administration of a recombinant adenovirus during the neonatal period.
The Journal of biological chemistry 1996;271(43):26536-42.
1996: Jobst Greeve; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
Induction of hepatic apolipoprotein B mRNA editing for reducing serum cholesterol levels: a breakthrough or a disaster?
Hepatology (Baltimore, Md.) 1996;24(4):964-6.
1996: Jobst Greeve; V K Jona; Namita Roy-Chowdhury; M S Horwitz; Jayanta Roy-Chowdhury
Hepatic gene transfer of the catalytic subunit of the apolipoprotein B mRNA editing enzyme results in a reduction of plasma LDL levels in normal and watanabe heritable hyperlipidemic rabbits.
Journal of lipid research 1996;37(9):2001-17.
1996: I K Schumacher; T Okamoto; B H Kim; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Ira J Fox
Transplantation of conditionally immortalized hepatocytes to treat hepatic encephalopathy.
Hepatology (Baltimore, Md.) 1996;24(2):337-43.
1996: B H Kim; M Takahashi; K Tada; Piter J Bosma; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
Cell and gene therapy for inherited deficiency of bilirubin glucuronidation.
Journal of perinatology : official journal of the California Perinatal Association 1996;16(3 Pt 2):S67-72.
1996: HO Jauregui; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Use of mammalian liver cells for artificial liver support.
Cell transplantation 1996;5(3):353-67.
1996: J Seppen; K Tada; S Hellwig; C T Bakker; Vinayaka R Prasad; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Piter J Bosma; Ronald P J Oude Elferink
Bilirubin glucuronidation by intact Gunn rat fibroblasts expressing bilirubin UDP-glucuronosyltransferase.
The Biochemical journal 1996;314 ( Pt 2)():477-83.
1996: Namita Roy-Chowdhury; R M Hays; V R Bommineni; Nicholas Franki; Jayanta Roy-Chowdhury; C H Wu; G Y Wu
Microtubular disruption prolongs the expression of human bilirubin-uridinediphosphoglucuronate-glucuronosyltransferase-1 gene transferred into Gunn rat livers.
The Journal of biological chemistry 1996;271(4):2341-6.
1995: Eun K Yang; K Kashfi; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; A J Dannenberg
Phenolic antioxidants induce UDP-glucuronosyltransferase in rat liver.
Annals of the New York Academy of Sciences 1995;768():231-6.
1995: G W Wu; Jayanta Roy-Chowdhury; V R Bommineni; S K Basu; C H Wu; Namita Roy-Chowdhury
Fate of DNA targeted to hepatocytes by asialoglycoprotein polylysine conjugates.
Proceedings of the Association of American Physicians 1995;107(2):211-7.
1995: A J Fabrega; V R Bommineni; J Blanchard; S Tetali; P A Rivas; Raymond Pollak; K Sengupta; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Amelioration of analbuminemia by transplantation of allogeneic hepatocytes in tolerized rats.
Transplantation 1995;59(9):1362-4.
1995: Ira J Fox; Namita Roy-Chowdhury; Sanjeev Gupta; R Kondapalli; Michael L Schilsky; Richard J Stockert; Jayanta Roy-Chowdhury
Conditional immortalization of Gunn rat hepatocytes: an ex vivo model for evaluating methods for bilirubin-UDP-glucuronosyltransferase gene transfer.
Hepatology (Baltimore, Md.) 1995;21(3):837-46.
1994: J Seppen; Piter J Bosma; B G Goldhoorn; C T Bakker; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; Peter L M Jansen; Ronald P J Oude Elferink
Discrimination between Crigler-Najjar type I and II by expression of mutant bilirubin uridine diphosphate-glucuronosyltransferase.
The Journal of clinical investigation 1994;94(6):2385-91.
1994: Philippe Labrune; Anne Myara; michelle hadchouel; F Ronchi; O Bernard; François Trivin; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; Arnold Munnich; Marie-Hélène Odièvre
Genetic heterogeneity of Crigler-Najjar syndrome type I: a study of 14 cases.
Human genetics 1994;94(6):693-7.
1994: K Kashfi; Eun K Yang; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; A J Dannenberg
Regulation of uridine diphosphate glucuronosyltransferase expression by phenolic antioxidants.
Cancer research 1994;54(22):5856-9.
1994: V R Bommineni; Namita Roy-Chowdhury; G Y Wu; C H Wu; Nicholas Franki; R M Hays; Jayanta Roy-Chowdhury
Depolymerization of hepatocellular microtubules after partial hepatectomy.
The Journal of biological chemistry 1994;269(40):25200-5.
1994: Piter J Bosma; J Seppen; B Goldhoorn; C Bakker; Ronald P J Oude Elferink; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; Peter L M Jansen
Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man.
The Journal of biological chemistry 1994;269(27):17960-4.
1993: Sanjeev Gupta; R P Vemuru; P R Yerneni; Namita Roy-Chowdhury; R K Jagtiani; David A Shafritz; Robert D Burk; Jayanta Roy-Chowdhury
Hepatocyte transplantation: prolonged cell survival following ex vivo manipulation and release from culture matrix components.
Transplantation proceedings 1993;25(3):2370-4.
1993: Namita Roy-Chowdhury; C H Wu; G Y Wu; P C Yerneni; V R Bommineni; Jayanta Roy-Chowdhury
Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. Prolonged persistence in cytoplasmic vesicles after partial hepatectomy.
The Journal of biological chemistry 1993;268(15):11265-71.
1993: Jayanta Roy-Chowdhury; R Kondapalli; Namita Roy-Chowdhury
Gunn rat: a model for inherited deficiency of bilirubin glucuronidation.
Advances in veterinary science and comparative medicine 1993;37():149-73.
1992: T J Huang; Jayanta Roy-Chowdhury; P Lahiri; P C Yerneni; V R Bommineni; I M Arias; Namita Roy-Chowdhury
Prenatal diagnosis of bilirubin-UDP-glucuronosyltransferase deficiency in rats by genomic DNA analysis.
Hepatology (Baltimore, Md.) 1992;16(3):756-62.
1992: Piter J Bosma; Jayanta Roy-Chowdhury; T J Huang; P Lahiri; Ronald P J Oude Elferink; H H Van Es; M Lederstein; P F Whitington; Peter L M Jansen; Namita Roy-Chowdhury
Mechanisms of inherited deficiencies of multiple UDP-glucuronosyltransferase isoforms in two patients with Crigler-Najjar syndrome, type I.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992;6(10):2859-63.
1992: Piter J Bosma; Namita Roy-Chowdhury; B G Goldhoorn; M H Hofker; Ronald P J Oude Elferink; Peter L M Jansen; Jayanta Roy-Chowdhury
Sequence of exons and the flanking regions of human bilirubin-UDP-glucuronosyltransferase gene complex and identification of a genetic mutation in a patient with Crigler-Najjar syndrome, type I.
Hepatology (Baltimore, Md.) 1992;15(5):941-7.
1992: James M Wilson; M Grossman; C H Wu; Namita Roy-Chowdhury; G Y Wu; Jayanta Roy-Chowdhury
Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits.
The Journal of biological chemistry 1992;267(2):963-7.
1991: Jayanta Roy-Chowdhury; M Grossman; Sanjeev Gupta; Namita Roy-Chowdhury; James R Baker Jr; J M Wilson
Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits.
Science (New York, N.Y.) 1991;254(5039):1802-5.
1991: Jayanta Roy-Chowdhury; T J Huang; K Kesari; M Lederstein; I M Arias; Namita Roy-Chowdhury
Molecular basis for the lack of bilirubin-specific and 3-methylcholanthrene-inducible UDP-glucuronosyltransferase activities in Gunn rats. The two isoforms are encoded by distinct mRNA species that share an identical single base deletion.
The Journal of biological chemistry 1991;266(27):18294-8.
1991: Y Adachi; Rolf Kinne; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; L Theilmann; T Tran; I M Arias
Uptake of bilirubin glucuronides by isolated rat hepatocytes.
Gastroenterologia Japonica 1991;26(3):350-5.
1991: Namita Roy-Chowdhury; M A Saber; P Lahiri; P I Mackenzie; Phyllis M Novikoff; F F Becker; Jayanta Roy-Chowdhury
Expression of specific UDP-glucuronosyltransferase isoforms in carcinogen-induced preneoplastic rat liver nodules.
Hepatology (Baltimore, Md.) 1991;13(1):38-46.
1991: P Lahiri; P R Yerneni; Z Khan; Achilles A Demetriou; A D Moscioni; Daniel Shouval; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
Bilirubin conjugates produced by human, dog, and rat hepatocytes transplanted into athymic Gunn rats.
Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians 1991;2(2):58-63.
1990: James M Wilson; Namita Roy-Chowdhury; M Grossman; R Wajsman; A Epstein; R C Mulligan; Jayanta Roy-Chowdhury
Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8437-41.
1990: Sanjeev Gupta; Namita Roy-Chowdhury; R Jagtiani; Kurt E. Gustin; E Aragona; David A Shafritz; Jayanta Roy-Chowdhury; Robert D Burk
A novel system for transplantation of isolated hepatocytes utilizing HBsAg-producing transgenic donor cells.
Transplantation 1990;50(3):472-5.
1990: Mostafa El Awady; Jayanta Roy-Chowdhury; K Kesari; H van Es; Peter L M Jansen; M Lederstein; I M Arias; Namita Roy-Chowdhury
Mechanism of the lack of induction of UDP-glucuronosyltransferase activity in Gunn rats by 3-methylcholanthrene. Identification of a truncated enzyme.
The Journal of biological chemistry 1990;265(18):10752-8.
1990: Y Adachi; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; Rolf Kinne; T Tran; H Kobayashi; I M Arias
Hepatic uptake of bilirubin diglucuronide: analysis by using sinusoidal plasma membrane vesicles.
Journal of biochemistry 1990;107(5):749-54.
1989: A D Moscioni; Jayanta Roy-Chowdhury; R Barbour; L L Brown; Namita Roy-Chowdhury; L S Competiello; P Lahiri; Achilles A Demetriou
Human liver cell transplantation. Prolonged function in athymic-Gunn and athymic-analbuminemic hybrid rats.
Gastroenterology 1989;96(6):1546-51.
1989: Peter I Mackenzie; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Characterization and regulation of rat liver UDP glucuronosyltransferases.
Clinical and experimental pharmacology & physiology 1989;16(6):501-4.
1989: A Patel; Mark Hardy; Namita Roy-Chowdhury; R Wajsman; M Sandoval; J M Wilson; Jayanta Roy-Chowdhury
Long-term correction of genetic defect of liver function in rat by transplantation of liver cells after ultraviolet irradiation.
Molecular biology & medicine 1989;6(2):187-96.
1987: H Raza; W G Levine; Namita Roy-Chowdhury; Jayanta Roy-Chowdhury
Microsomal azoreduction and glucuronidation in the metabolism of dimethylaminoazobenzene by the rat liver.
Xenobiotica; the fate of foreign compounds in biological systems 1987;17(6):669-77.
1987: Namita Roy-Chowdhury; F Gross; A D Moscioni; M Kram; I M Arias; Jayanta Roy-Chowdhury
Isolation of multiple normal and functionally defective forms of uridine diphosphate-glucuronosyltransferase from inbred Gunn rats.
The Journal of clinical investigation 1987;79(2):327-34.
1986: Achilles A Demetriou; SM Levenson; Phyllis M Novikoff; A B Novikoff; Namita Roy-Chowdhury; J Whiting; A Reisner; Jayanta Roy-Chowdhury
Survival, organization, and function of microcarrier-attached hepatocytes transplanted in rats.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7475-9.
1986: Achilles Demetriou; J F Whiting; D Feldman; SM Levenson; Namita Roy-Chowdhury; A D Moscioni; M Kram; Jayanta Roy-Chowdhury
Replacement of liver function in rats by transplantation of microcarrier-attached hepatocytes.
Science (New York, N.Y.) 1986;233(4769):1190-2.
1986: Achilles Demetriou; J Whiting; SM Levenson; Namita Roy-Chowdhury; Richard Schechner; S Michalski; D Feldman; Jayanta Roy-Chowdhury
New method of hepatocyte transplantation and extracorporeal liver support.
Annals of surgery 1986;204(3):259-71.
1986: Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; C N Falany; T R Tephly; I M Arias
Isolation and characterization of multiple forms of rat liver UDP-glucuronate glucuronosyltransferase.
The Biochemical journal 1986;233(3):827-37.
1986: Namita Roy-Chowdhury; I M Arias; M Lederstein; Jayanta Roy-Chowdhury
Substrates and products of purified rat liver bilirubin UDP-glucuronosyltransferase.
Hepatology (Baltimore, Md.) 1986;6(1):123-8.
1985: Jayanta Roy-Chowdhury; Phyllis M Novikoff; Namita Roy-Chowdhury; A B Novikoff
Distribution of UDPglucuronosyltransferase in rat tissue.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(9):2990-4.
1985: M Inoue; E Hirata; Y Morino; S Nagase; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; I M Arias
The role of albumin in the hepatic transport of bilirubin: studies in mutant analbuminemic rats.
Journal of biochemistry 1985;97(3):737-43.
1984: O W Portman; M Alexander; C E Cornelius; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; I M Arias
The effects of nutrition on unconjugated plasma bilirubin concentrations in squirrel monkeys.
Hepatology (Baltimore, Md.) 1984;4(3):454-60.
1984: O W Portman; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; M Alexander; C E Cornelius; I M Arias
A nonhuman primate model of Gilbert's syndrome.
Hepatology (Baltimore, Md.) 1984;4(2):175-9.
1984: Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; I M Arias
UDPglucuronosyltransferase deficiency in man and animals.
Biochemical Society transactions 1984;12(1):81-3.
1983: Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; A D Moscioni; R Tukey; T Tephly; I M Arias
Differential regulation by triiodothyronine of substrate-specific uridinediphosphoglucuronate glucuronosyl transferases in rat liver.
Biochimica et biophysica acta 1983;761(1):58-65.
1983: C N Falany; Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; T R Tephly
Steroid 3- and 17-OH UDP-glucuronosyltransferase activities in rat and rabbit liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 1983;11(5):426-32.
1983: Jayanta Roy-Chowdhury; Namita Roy-Chowdhury
Conjugation and excretion of bilirubin.
Seminars in liver disease 1983;3(1):11-23.
1982: Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; U Gärtner; Allan W Wolkoff; I M Arias
Bilirubin diglucuronide formation in intact rats and in isolated Gunn rat liver.
The Journal of clinical investigation 1982;69(3):595-603.
1982: Namita Roy-Chowdhury; Jayanta Roy-Chowdhury; I M Arias
Bile pigment composition and hepatic UDP-glucuronyl transferase activity in the fetal and adult dogfish shark, Squalus acanthias.
Comparative biochemistry and physiology. B, Comparative biochemistry 1982;73(3):651-3.
1981: Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; G Wu; R Shouval; I M Arias
Bilirubin mono- and diglucuronide formation by human liver in vitro: assay by high-pressure liquid chromatography.
Hepatology (Baltimore, Md.) 1981;1(6):622-7.
1979: Jayanta Roy-Chowdhury; Namita Roy-Chowdhury; M M Bhargava; I M Arias
Purification and partial characterization of rat liver bilirubin glucuronoside glucuronosyltransferase.
The Journal of biological chemistry 1979;254(17):8336-9.