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An Billiau

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A Luyckx; Omer Rutgeerts; E Schouppe; Jo A Van Ginderachter; Mark Waer; Timothy Devos; D Dierickx; Sabine Fevery; C Koks; Caroline Lenaerts; An D Billiau
Subset characterization of myeloid-derived suppressor cells arising during induction of BM chimerism in mice.
Ariane Luyckx; Omer Rutgeerts; Elio Schouppe; Jo A Van Ginderachter; Mark Waer; Timothy Devos; Daan Dierickx; Sabine Fevery; Caroline Lenaerts; An D Billiau
G-CSF stem cell mobilization in human donors induces polymorphonuclear and mononuclear myeloid-derived suppressor cells.
Leen Willems; Caroline Lenaerts; Shengqiao Li; Omer Rutgeerts; Mark Waer; An D Billiau
IL-7 is required for the development of the intrinsic function of marginal zone B cells and the marginal zone microenvironment.

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All Publications

2012: A Luyckx; Omer Rutgeerts; E Schouppe; Jo A Van Ginderachter; Mark Waer; Timothy Devos; D Dierickx; Sabine Fevery; C Koks; Caroline Lenaerts; An D Billiau
Subset characterization of myeloid-derived suppressor cells arising during induction of BM chimerism in mice.
Bone marrow transplantation 2012;47(7):985-92.
2012: Ariane Luyckx; Omer Rutgeerts; Elio Schouppe; Jo A Van Ginderachter; Mark Waer; Timothy Devos; Daan Dierickx; Sabine Fevery; Caroline Lenaerts; An D Billiau
G-CSF stem cell mobilization in human donors induces polymorphonuclear and mononuclear myeloid-derived suppressor cells.
Clinical immunology (Orlando, Fla.) 2012;143(1):83-7.
2011: Leen Willems; Caroline Lenaerts; Shengqiao Li; Omer Rutgeerts; Mark Waer; An D Billiau
IL-7 is required for the development of the intrinsic function of marginal zone B cells and the marginal zone microenvironment.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(7):3587-94.
2011: Ariane Luyckx; Lien De Somer; Sandra Jacobs; Omer Rutgeerts; Caroline Lenaerts; Valerie D Roobrouck; Catherine M Verfaillie; Mark Waer; Stefaan W Van Gool; An D Billiau
Oct4-negative multipotent adult progenitor cells and mesenchymal stem cells as regulators of T-cell alloreactivity in mice.
Immunology letters 2011;137(1-2):78-81.
2011: Ben Sprangers; Bart Van Wijmeersch; A Luyckx; Xavier Sagaert; B Verbinnen; Omer Rutgeerts; C Lenaerts; Thomas Tousseyn; Bruno Dubois; Mark Waer; An D Billiau
Subclinical GvHD in non-irradiated F1 hybrids: severe lymphoid-tissue GvHD causing prolonged immune dysfunction.
Bone marrow transplantation 2011;46(4):586-96.
2011: Lien De Somer; Ben Sprangers; Sabine Fevery; Omer Rutgeerts; Caroline Lenaerts; Louis Boon; Mark Waer; An D Billiau
Recipient lymphocyte infusion in MHC-matched bone marrow chimeras induces a limited lymphohematopoietic host-versus-graft reactivity but a significant antileukemic effect mediated by CD8+ T cells and natural killer cells.
Haematologica 2011;96(3):424-31.
2010: Lien De Somer; Sabine Fevery; dominique ma bullens; Omer Rutgeerts; Caroline Lenaerts; Chantal Mathieu; Louis Boon; Ahmad Kasran; Mark Waer; An D Billiau
Murine bone marrow chimeras developing autoimmunity after CTLA-4-blockade show an expansion of T regulatory cells with an activated cytokine profile.
Immunology letters 2010;133(1):49-53.
2010: An D Billiau; Michèle Loop; Phu-Quoc Le; Françoise Berthet; Pierre Philippet; Ahmad Kasran; Carine H Wouters
Etanercept improves linear growth and bone mass acquisition in MTX-resistant polyarticular-course juvenile idiopathic arthritis.
Rheumatology (Oxford, England) 2010;49(8):1550-8.
2010: Ariane Luyckx; Lien De Somer; Omer Rutgeerts; Mark Waer; Catherine M Verfaillie; Stefaan Van Gool; An D Billiau
Mouse MAPC-mediated immunomodulation: Cell-line dependent variation.
Experimental hematology 2010;38(1):1-2.
2009: Shengqiao Li; Mark Waer; An D Billiau
Xenotransplantation: role of natural immunity.
Transplant immunology 2009;21(2):70-4.
2009: Yuqian Hu; An D Billiau; Anna Verdonck; Carine Wouters; Carine Carels
Variation in dentofacial morphology and occlusion in juvenile idiopathic arthritis subjects: a case-control study.
European journal of orthodontics 2009;31(1):51-8.
2009: Ben Sprangers; Bart Van Wijmeersch; A Luyckx; Xavier Sagaert; L De Somer; Omer Rutgeerts; Caroline Lenaerts; Willy Landuyt; Nancy Boeckx; Bénédicte Dubois; Christiane De Wolf-Peeters; Mark Waer; An D Billiau
Allogeneic bone marrow transplantation and donor lymphocyte infusion in a mouse model of irradiation-induced myelodysplastic/myeloproliferation syndrome (MD/MPS): evidence for a graft-versus-MD/MPS effect.
Leukemia 2009;23(2):340-9.
2008: Geneviève Gowing; Thomas Philips; Bart Van Wijmeersch; Jean-Nicolas Audet; Maarten Dewil; Ludo Van Den Bosch; An D Billiau; Wim Robberecht; Jean-Pierre Julien
Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(41):10234-44.
2008: Hilde Kelchtermans; An D Billiau; Patrick Matthys
How interferon-gamma keeps autoimmune diseases in check.
Trends in immunology 2008;29(10):479-86.
2008: Bert Verbinnen; An D Billiau; Jan Vermeiren; Georgina Galicia; dominique ma bullens; Louis Boon; Pascal Cadot; Greet Hens; Christiane Dewolf Peeters; Stefaan W Van Gool; Jan L Ceuppens
Contribution of regulatory T cells and effector T cell deletion in tolerance induction by costimulation blockade.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1034-42.
2008: Bart Van Wijmeersch; Ben Sprangers; Bénédicte Dubois; Mark Waer; An D Billiau
Autologous and allogeneic hematopoietic stem cell transplantation for Multiple Sclerosis: perspective on mechanisms of action.
Journal of neuroimmunology 2008;197(2):89-98.
2008: Ben Sprangers; Mark Waer; An D Billiau
Xenotransplantation: where are we in 2008?
Kidney international 2008;74(1):14-21.
2008: Timothy Devos; Li Shengqiao; Conny Gysemans; Yehong Yan; Boudewijn Van Damme; Molly Nelson-Holte; An D Billiau; Mark Waer; Chantal Mathieu
Late CD8+ T cell-dependent xenoantibody production in innate tolerant nude rats after hamster islet grafting but not after hamster heart grafting.
Transplantation 2008;85(10):1489-95.
2008: Marc Tjwa; Lola Bellido-Martin; Yuan Lin; Esther Lutgens; Stephane Plaisance; Françoise Bono; Nathalie Delesque-Touchard; Caroline Hervé; Rute Moura; An D Billiau; Cristina Aparicio; Marcel Levi; Mat Daemen; Mieke Dewerchin; Florea Lupu; Jef Arnout; Jean-Marc Herbert; Mark Waer; Pablo García de Frutos; Björn Dahlbäck; Peter Carmeliet; Marc F Hoylaerts; Lieve Moons
Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
Blood 2008;111(8):4096-105.
2008: Timothy Devos; Ben Sprangers; Yuan Lin; Shengqiao Li; Yehong Yan; Willy Landuyt; Caroline Lenaerts; Omer Rutgeerts; Jozef Goebels; dominique ma bullens; Christiane De Wolf-Peeters; Chantal Mathieu; Mark Waer; An D Billiau
Occurrence of autoimmunity after xenothymus transplantation in T-cell-deficient mice depends on the thymus transplant technique.
Transplantation 2008;85(4):640-4.
2008: Xabier L Aranguren; Jonathan D McCue; Benoit Hendrickx; Xiao-Hong Zhu; Fei Du; Eleanor Chen; Beatriz Pelacho; Iván Peñuelas; Gloria Abizanda; Maialen Uriz; Sarah A Frommer; Jeffrey J Ross; Betsy A Schroeder; Meredith S Seaborn; Joshua R Adney; Julianna Hagenbrock; Nathan H Harris; Yi Zhang; Xiaoliang Zhang; Molly H Nelson-Holte; Yuehua Jiang; An D Billiau; Wei Chen; Felipe Prósper; Catherine M Verfaillie; Aernout Luttun
Multipotent adult progenitor cells sustain function of ischemic limbs in mice.
The Journal of clinical investigation 2008;118(2):505-14.
2007: Shengqiao Li; Yehong Yan; Yuan Lin; dominique ma bullens; Omer Rutgeerts; Jozef Goebels; Constant Segers; Louis Boon; Ahmad Kasran; Rita De Vos; Christiane Dewolf Peeters; Mark Waer; An D Billiau
Rapidly induced, T-cell independent xenoantibody production is mediated by marginal zone B cells and requires help from NK cells.
Blood 2007;110(12):3926-35.
2007: An D Billiau; Yuqian Hu; Anna Verdonck; Carine Carels; Carine Wouters
Temporomandibular joint arthritis in juvenile idiopathic arthritis: prevalence, clinical and radiological signs, and relation to dentofacial morphology.
The Journal of rheumatology 2007;34(9):1925-33.
2007: An D Billiau; Peter Witters; Berten Ceulemans; Ahmad Kasran; Carine Wouters; Lieven Lagae
Intravenous immunoglobulins in refractory childhood-onset epilepsy: effects on seizure frequency, EEG activity, and cerebrospinal fluid cytokine profile.
Epilepsia 2007;48(9):1739-49.
2007: An D Billiau
Interferons: the pathways of discovery. II. Immunomodulatory, in vivo and applied aspects.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2007;39(4):241-65.
2007: Ben Sprangers; Bart Van Wijmeersch; Sabine Fevery; Mark Waer; An D Billiau
Experimental and clinical approaches for optimization of the graft-versus-leukemia effect.
Nature clinical practice. Oncology 2007;4(7):404-14.
2007: Sabine Fevery; An D Billiau; Ben Sprangers; Omer Rutgeerts; Caroline Lenaerts; Jozef Goebels; Willy Landuyt; Ahmad Kasran; Louis Boon; Xavier Sagaert; Christiane De Wolf-Peeters; Mark Waer; Peter Vandenberghe
CTLA-4 blockade in murine bone marrow chimeras induces a host-derived antileukemic effect without graft-versus-host disease.
Leukemia 2007;21(7):1451-9.
2007: Bart Van Wijmeersch; Ben Sprangers; Omer Rutgeerts; Caroline Lenaerts; Willy Landuyt; Mark Waer; An D Billiau; Bénédicte Dubois
Allogeneic bone marrow transplantation in models of experimental autoimmune encephalomyelitis: evidence for a graft-versus-autoimmunity effect.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2007;13(6):627-37.
2007: Hilde Kelchtermans; Sofie Struyf; Bert De Klerck; Tania Mitera; Marijke Alen; Lies Geboes; Maarten Van Balen; Chris Dillen; Willy Put; Conny Gysemans; An D Billiau; Jo Van Damme; Patrick Matthys
Protective role of IFN-gamma in collagen-induced arthritis conferred by inhibition of mycobacteria-induced granulocyte chemotactic protein-2 production.
Journal of leukocyte biology 2007;81(4):1044-53.
2007: Ben Sprangers; Sabine Fevery; Bart Van Wijmeersch; Lien De Somer; Mark Waer; An D Billiau
Can graft-versus-leukemia reactivity be dissociated from graft-versus-host disease?
Frontiers in bioscience : a journal and virtual library 2007;12():4568-94.
2006: An D Billiau
Interferon: the pathways of discovery I. Molecular and cellular aspects.
Cytokine & growth factor reviews 2006;17(5):381-409.
2006: An D Billiau
Anti-inflammatory properties of Type I interferons.
Antiviral research 2006;71(2-3):108-16.
2006: Ben Sprangers; Mark Waer; An D Billiau
Xenograft rejection--all that glitters is not Gal.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006;21(6):1486-8.
2006: Mathijs Baens; Sabine Fevery; Xavier Sagaert; Heidi Noels; Sofie Hagens; Vicky Broeckx; An D Billiau; Christiane De Wolf-Peeters; Peter Marynen
Selective expansion of marginal zone B cells in Emicro-API2-MALT1 mice is linked to enhanced IkappaB kinase gamma polyubiquitination.
Cancer research 2006;66(10):5270-7.
2006: Mathijs Baens; Heidi Noels; Vicky Broeckx; Sofie Hagens; Sabine Fevery; An D Billiau; Hugo Vankelecom; Peter Marynen
The dark side of EGFP: defective polyubiquitination.
PloS one 2006;1():e54.
2006: Axel Jeurissen; An D Billiau; Leen Moens; Li Shengqiao; Willy Landuyt; Greet Wuyts; Louis Boon; Mark Waer; Jan L Ceuppens; Xavier Bossuyt
CD4+ T lymphocytes expressing CD40 ligand help the IgM antibody response to soluble pneumococcal polysaccharides via an intermediate cell type.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):529-36.
2005: Orhun H Kantarci; An Goris; David D Hebrink; Shirley Heggarty; S Cunningham; Iraide Alloza; Elizabeth J Atkinson; Mariza de Andrade; Cynthia T McMurray; CA Graham; Stanley A Hawkins; An D Billiau; Bénédicte Dubois; Brian G Weinshenker; Koen Vandenbroeck
IFNG polymorphisms are associated with gender differences in susceptibility to multiple sclerosis.
Genes and immunity 2005;6(2):153-61.
2005: An D Billiau; Tania Roskams; Rita Van Damme-Lombaerts; Patrick Matthys; Carine Wouters
Macrophage activation syndrome: characteristic findings on liver biopsy illustrating the key role of activated, IFN-gamma-producing lymphocytes and IL-6- and TNF-alpha-producing macrophages.
Blood 2005;105(4):1648-51.
2005: Bert De Klerck; Lies Geboes; Sigrid Hatse; Hilde Kelchtermans; Yves Meyvis; Kurt Vermeire; Gary J Bridger; An D Billiau; Dominique Schols; Patrick Matthys
Pro-inflammatory properties of stromal cell-derived factor-1 (CXCL12) in collagen-induced arthritis.
Arthritis research & therapy 2005;7(6):R1208-20.
2005: Hilde Kelchtermans; Bert De Klerck; Tania Mitera; Maarten Van Balen; dominique ma bullens; An D Billiau; Georges Leclercq; Patrick Matthys
Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma.
Arthritis research & therapy 2005;7(2):R402-15.
2005: An D Billiau; Carine Wouters; Lieven Lagae
Epilepsy and the immune system: is there a link?
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 2005;9(1):29-42.
2004: Timothy Devos; Mark Waer; An D Billiau
Cross-species chemoattraction and xenograft failure: do neutrophils play a role?
Transplantation 2004;78(12):1717-8.
2004: An D Billiau; Bernd C Kieseier; Hans-Peter Hartung
Biologic role of interferon beta in multiple sclerosis.
Journal of neurology 2004;251 Suppl 2():II10-4.
2004: Bert De Klerck; Isabelle Carpentier; Rik J U Lories; Yvette Habraken; Jacques Piette; Geert Carmeliet; Rudi Beyaert; An D Billiau; Patrick Matthys
Enhanced osteoclast development in collagen-induced arthritis in interferon-gamma receptor knock-out mice as related to increased splenic CD11b+ myelopoiesis.
Arthritis research & therapy 2004;6(3):R220-31.
2003: An Goris; Stephen Sawcer; Koen Vandenbroeck; Herwig Carton; An D Billiau; Efrosini Setakis; Alastair Compston; Bénédicte Dubois
New candidate loci for multiple sclerosis susceptibility revealed by a whole genome association screen in a Belgian population.
Journal of neuroimmunology 2003;143(1-2):65-9.
2003: Patrick Matthys; Rik J U Lories; Bert De Klerck; Hubertine Heremans; Frank P Luyten; An D Billiau
Dependence on interferon-gamma for the spontaneous occurrence of arthritis in DBA/1 mice.
Arthritis and rheumatism 2003;48(10):2983-8.
2003: An D Billiau; Sabine Fevery; Omer Rutgeerts; Willy Landuyt; Mark Waer
Transient expansion of Mac1+Ly6-G+Ly6-C+ early myeloid cells with suppressor activity in spleens of murine radiation marrow chimeras: possible implications for the graft-versus-host and graft-versus-leukemia reactivity of donor lymphocyte infusions.
Blood 2003;102(2):740-8.
2002: An Goris; Shirley Heggarty; Maria Giovanna Marrosu; C Graham; An D Billiau; Koen Vandenbroeck
Linkage disequilibrium analysis of chromosome 12q14-15 in multiple sclerosis: delineation of a 118-kb interval around interferon-gamma (IFNG) that is involved in male versus female differential susceptibility.
Genes and immunity 2002;3(8):470-6.
2002: Patrick Matthys; H Dooms; Pieter Rottiers; Tania Mitera; L Overgergh; G Leclercq; An D Billiau; Johan Grooten
Induction of IL-15 by TCR/CD3 aggregation depends on IFN-gamma and protects against apoptosis of immature thymocytes in vivo.
Clinical and experimental immunology 2002;130(3):379-85.
2002: An D Billiau; Sabine Fevery; Omer Rutgeerts; Willy Landuyt; Mark Waer
Crucial role of timing of donor lymphocyte infusion in generating dissociated graft-versus-host and graft-versus-leukemia responses in mice receiving allogeneic bone marrow transplants.
Blood 2002;100(5):1894-902.
2002: Koen Vandenbroeck; Iraide Alloza; Dirk Brehmer; An D Billiau; Paul Proost; Neil McFerran; Stefan Rüdiger; Brian Walker
The conserved helix C region in the superfamily of interferon-gamma /interleukin-10-related cytokines corresponds to a high-affinity binding site for the HSP70 chaperone DnaK.
The Journal of biological chemistry 2002;277(28):25668-76.
2002: An D Billiau; Freddy Cornillie; Carine Wouters
Infliximab for systemic onset juvenile idiopathic arthritis: experience in 3 children.
The Journal of rheumatology 2002;29(5):1111-4.
2001: Paul Proost; Evemie Schutyser; Patricia Menten; Sofie Struyf; Anja Wuyts; Ghislain Opdenakker; Michel detheux; Marc Parmentier; Christine Durinx; Anne-Marie Lambeir; J Neyts; Sandra Liekens; P C Maudgal; An D Billiau; Jo Van Damme
Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties.
Blood 2001;98(13):3554-61.
2001: An D Billiau; Patrick Matthys
Modes of action of Freund's adjuvants in experimental models of autoimmune diseases.
Journal of leukocyte biology 2001;70(6):849-60.
2001: Patrick Matthys; Sigrid Hatse; Kurt Vermeire; Anja Wuyts; Gary J Bridger; Geoffrey Henson; Erik De Clercq; An D Billiau; Dominique Schols
AMD3100, a potent and specific antagonist of the stromal cell-derived factor-1 chemokine receptor CXCR4, inhibits autoimmune joint inflammation in IFN-gamma receptor-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4686-92.
2001: Patrick Matthys; Kurt Vermeire; An D Billiau
Mac-1(+) myelopoiesis induced by CFA: a clue to the paradoxical effects of IFN-gamma in autoimmune disease models.
Trends in immunology 2001;22(7):367-71.
2001: An D Billiau; Hassan Sefrioui; Lut Overbergh; Omer Rutgeerts; Jozef Goebels; Mark Waer
The graft-versus-leukemia effect in allogeneic irradiation bone marrow chimeras: possible suppressive role of irradiation-induced TGF-beta.
Transplantation proceedings 2001;33(1-2):336-7.
2001: An D Billiau; Hassan Sefrioui; Lut Overbergh; Omer Rutgeerts; Jozef Goebels; Chantal Mathieu; Mark Waer
Transforming growth factor-beta inhibits lymphokine activated killer cytotoxicity of bone marrow cells: implications for the graft-versus-leukemia effect in irradiation allogeneic bone marrow chimeras.
Transplantation 2001;71(2):292-9.
2000: Ellen Martens; Iraide Alloza; Christopher J Scott; An D Billiau; Koen Vandenbroeck
Protein disulfide isomerase-mediated cell-free assembly of recombinant interleukin-12 p40 homodimers.
European journal of biochemistry / FEBS 2000;267(22):6679-83.
2000: Koen Vandenbroeck; Pierre Fiten; Isabelle Ronsse; An Goris; I Porru; Cristina Melis; Marcella Rolesu; An D Billiau; Maria Giovanna Marrosu; Ghislain Opdenakker
High-resolution analysis of IL-6 minisatellite polymorphism in Sardinian multiple sclerosis: effect on course and onset of disease.
Genes and immunity 2000;1(7):460-3.
2000: Patrick Matthys; Kurt Vermeire; Hubertine Heremans; An D Billiau
The protective effect of IFN-gamma in experimental autoimmune diseases: a central role of mycobacterial adjuvant-induced myelopoiesis.
Journal of leukocyte biology 2000;68(4):447-54.
2000: Hassan Sefrioui; An D Billiau; Mark Waer
Graft-versus-leukemia effect in minor antigen mismatched chimeras given delayed donor leucocyte infusion: immunoregulatory aspects and role of donor T and ASGM1-positive cells.
Transplantation 2000;70(2):348-53.
2000: A D'Haese; Anja Wuyts; Chris Dillen; B Dubois; An D Billiau; Hubertine Heremans; Jo Van Damme; Bernd Arnold; Ghislain Opdenakker
In vivo neutrophil recruitment by granulocyte chemotactic protein-2 is assisted by gelatinase B/MMP-9 in the mouse.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2000;20(7):667-74.
2000: Kurt Vermeire; Leen Thielemans; Patrick Matthys; An D Billiau
The effects of NO synthase inhibitors on murine collagen-induced arthritis do not support a role of NO in the protective effect of IFN-gamma.
Journal of leukocyte biology 2000;68(1):119-24.
2000: Iveta Vancová; E Martens; Koen Vandenbroeck; Eva Kontseková; An D Billiau; Peter Kontsek
Low pH does not rearrange antigenic structure of porcine interferon gamma but inhibits its receptor binding.
Acta virologica 2000;44(2):121-2.
2000: Koen Vandenbroeck; Cornelia Hardt; J Louage; Pierre Fiten; S Jäckel; Isabelle Ronsse; Jörg T Epplen; Luigi M E Grimaldi; Tomas Olsson; Maria Giovanna Marrosu; An D Billiau; Ghislain Opdenakker
Lack of association between the interferon regulatory factor-1 (IRF1) locus at 5q31.1 and multiple sclerosis in Germany, northern Italy, Sardinia and Sweden.
Genes and immunity 2000;1(4):290-2.
2000: Y Tagawa; Patrick Matthys; Hubertine Heremans; Chris Dillen; Zahur Zaman; Y Iwakura; An D Billiau
Bimodal role of endogenous interleukin-6 in concanavalin A-induced hepatitis in mice.
Journal of leukocyte biology 2000;67(1):90-6.
2000: Hubertine Heremans; Chris Dillen; M Groenen; Patrick Matthys; An D Billiau
Role of interferon-gamma and nitric oxide in pulmonary edema and death induced by lipopolysaccharide.
American journal of respiratory and critical care medicine 2000;161(1):110-7.
1999: Hassan Sefrioui; An D Billiau; Lut Overbergh; Omer Rutgeerts; Mark Waer
Influence of the additional injection of host-type bone marrow on the immune tolerance of minor antigen-mismatched chimeras: possible involvement of double-negative (natural killer) T cells.
Transplantation 1999;68(10):1560-7.
1999: Patrick Matthys; Kurt Vermeire; Tania Mitera; Hubertine Heremans; S Huang; Dominique Schols; Christiane De Wolf-Peeters; An D Billiau
Enhanced autoimmune arthritis in IFN-gamma receptor-deficient mice is conditioned by mycobacteria in Freund's adjuvant and by increased expansion of Mac-1+ myeloid cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3503-10.
1999: An Goris; C Epplen; Pierre Fiten; M Andersson; Raffaele Murru; Francesca L Sciacca; Isabelle Ronsse; S Jäckel; Jörg T Epplen; Maria Giovanna Marrosu; Tomas Olsson; Luigi M E Grimaldi; Ghislain Opdenakker; An D Billiau; Koen Vandenbroeck
Analysis of an IFN-gamma gene (IFNG) polymorphism in multiple sclerosis in Europe: effect of population structure on association with disease.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1999;19(9):1037-46.
1999: Els Van Coillie; Ilse Van Aelst; Pierre Fiten; An D Billiau; Jo Van Damme; Ghislain Opdenakker
Transcriptional control of the human MCP-2 gene promoter by IFN-gamma and IL-1beta in connective tissue cells.
Journal of leukocyte biology 1999;66(3):502-11.
1999: Hubertine Heremans; Chris Dillen; M Groenen; Patrick Matthys; An D Billiau
Role of endogenous interleukin-12 (IL-12) in induced and spontaneous relapses of experimental autoimmune encephalomyelitis in mice.
European cytokine network 1999;10(2):171-80.
1999: Hassan Sefrioui; An D Billiau; Lut Overbergh; Omer Rutgeerts; Mark Waer
Tolerance in Mlsa mismatched chimeras prepared with allogeneic bone marrow alone or in combination with syngeneic bone marrow.
Transplantation proceedings 1999;31(1-2):702-3.
1999: Patricia Menten; Paul Proost; Sofie Struyf; Els Van Coillie; Willy Put; Jean-Pierre Lenaerts; René Conings; JM Jaspar; DD De Groote; An D Billiau; Ghislain Opdenakker; Jo Van Damme
Differential induction of monocyte chemotactic protein-3 in mononuclear leukocytes and fibroblasts by interferon-alpha/beta and interferon-gamma reveals MCP-3 heterogeneity.
European journal of immunology 1999;29(2):678-85.
1999: Koen Vandenbroeck; An Goris; Raffaele Murru; An D Billiau; Ghislain Opdenakker; Maria Giovanna Marrosu
A dinucleotide repeat polymorphism located in the IFN-alpha/beta gene cluster at chromosome 9p22 is not associated with multiple sclerosis in Sardinia.
Experimental and clinical immunogenetics 1999;16(1):26-9.
1998: An D Billiau; Hubertine Heremans; Kurt Vermeire; Patrick Matthys
Immunomodulatory properties of interferon-gamma. An update.
Annals of the New York Academy of Sciences 1998;856():22-32.
1998: Koen Vandenbroeck; Hans Nauwynck; A Vanderpooten; Kristien Van Reeth; Bruno Goddeeris; An D Billiau
Recombinant porcine IFN-gamma potentiates the secondary IgG and IgA responses to an inactivated suid herpesvirus-1 vaccine and reduces postchallenge weight loss and fever in pigs.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1998;18(9):739-44.
1998: Koen Vandenbroeck; An D Billiau
Interferon-gamma is a target for binding and folding by both Escherichia coli chaperone model systems GroEL/GroES and DnaK/DnaJ/GrpE.
Biochimie 1998;80(8-9):729-37.
1998: Patrick Matthys; Kurt Vermeire; Tania Mitera; Hubertine Heremans; S Huang; An D Billiau
Anti-IL-12 antibody prevents the development and progression of collagen-induced arthritis in IFN-gamma receptor-deficient mice.
European journal of immunology 1998;28(7):2143-51.
1998: Koen Vandenbroeck; Ellen Martens; An D Billiau
GroEL/ES chaperonins protect interferon-gamma against physicochemical stress--study of tertiary structure formation by alpha-casein quenching and ELISA.
European journal of biochemistry / FEBS 1998;251(1-2):181-8.
1997: Jo Van Damme; Anja Wuyts; Guy Froyen; Els Van Coillie; Sofie Struyf; An D Billiau; Paul Proost; J M Wang; Ghislain Opdenakker
Granulocyte chemotactic protein-2 and related CXC chemokines: from gene regulation to receptor usage.
Journal of leukocyte biology 1997;62(5):563-9.
1997: Peter Kontsek; Erik Martens; Koen Vandenbroeck; Eva Kontseková; G Waschütza; T Sareneva; An D Billiau
Structural immuno-analysis of human and porcine interferon gamma: identification of shared antigenic domain.
Cytokine 1997;9(8):550-5.
1997: Kurt Vermeire; Hubertine Heremans; Michel Vandeputte; S Huang; An D Billiau; Patrick Matthys
Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5507-13.
1997: N M Zhou; Patrick Matthys; C Polacek; Pierre Fiten; A Sato; An D Billiau; Guy Froyen
A competitive RT-PCR method for the quantitative analysis of cytokine mRNAs in mouse tissues.
Cytokine 1997;9(3):212-8.
1997: S Masure; L Paemen; Ilse Van Aelst; Pierre Fiten; Paul Proost; An D Billiau; Jo Van Damme; Ghislain Opdenakker
Production and characterization of recombinant active mouse gelatinase B from eukaryotic cells and in vivo effects after intravenous administration.
European journal of biochemistry / FEBS 1997;244(1):21-30.
1997: Guy Froyen; Paul Proost; Isabelle Ronsse; Tania Mitera; Annemie Haelens; Anja Wuyts; Ghislain Opdenakker; Jo Van Damme; An D Billiau
Cloning, bacterial expression and biological characterization of recombinant human granulocyte chemotactic protein-2 and differential expression of granulocyte chemotactic protein-2 and epithelial cell-derived neutrophil activating peptide-78 mRNAs.
European journal of biochemistry / FEBS 1997;243(3):762-9.
1997: Anja Wuyts; Paul Proost; Guy Froyen; Annemie Haelens; An D Billiau; Ghislain Opdenakker; Jo Van Damme
Purification and identification of human and mouse granulocyte chemotactic protein-2 isoforms.
Methods in enzymology 1997;287():13-33.
1997: Guy Froyen; An D Billiau
Potential therapeutic use of antibodies directed towards HuIFN-gamma.
Biotherapy (Dordrecht, Netherlands) 1997;10(1):49-57.
1996: Hubertine Heremans; Chris Dillen; M Groenen; E Martens; An D Billiau
Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon-gamma.
European journal of immunology 1996;26(10):2393-8.
1996: An D Billiau
Interferon-gamma in autoimmunity.
Cytokine & growth factor reviews 1996;7(1):25-34.
1996: An D Billiau
Interferon-gamma: biology and role in pathogenesis.
Advances in immunology 1996;62():61-130.
1995: K Norga; L Paemen; S Masure; Chris Dillen; Hubertine Heremans; An D Billiau; Herwig Carton; L Cuzner; T Olsson; Jo Van Damme
Prevention of acute autoimmune encephalomyelitis and abrogation of relapses in murine models of multiple sclerosis by the protease inhibitor D-penicillamine.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44(12):529-34.
1995: Patrick Matthys; Guy Froyen; L Verdot; S Huang; H Sobis; Jo Van Damme; Bernard Vray; M Aguet; An D Billiau
IFN-gamma receptor-deficient mice are hypersensitive to the anti-CD3-induced cytokine release syndrome and thymocyte apoptosis. Protective role of endogenous nitric oxide.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(8):3823-9.
1995: Guy Froyen; D Hendrix; Isabelle Ronsse; Pierre Fiten; E Martens; An D Billiau
Effect of VH and VL consensus sequence-specific primers on the binding and neutralizing potential of a single-chain FV directed towards HuIFN-gamma.
Molecular immunology 1995;32(7):515-21.
1995: Patrick Matthys; Tania Mitera; Hubertine Heremans; Jo Van Damme; An D Billiau
Anti-gamma interferon and anti-interleukin-6 antibodies affect staphylococcal enterotoxin B-induced weight loss, hypoglycemia, and cytokine release in D-galactosamine-sensitized and unsensitized mice.
Infection and immunity 1995;63(4):1158-64.
1994: An D Billiau; Patrick Matthys; E Martens; Hubertine Heremans
Effects of anti-interferon-gamma and anti-interleukin-6 antibodies in disease models in mice: antibodies as carriers of cytokines.
Journal of interferon research 1994;14(5):277-9.
1994: Koen Vandenbroeck; L Willems; An D Billiau; Ghislain Opdenakker; Roger Huybrechts
Glycoform heterogeneity of porcine interferon-gamma expressed in Sf9 cells.
Lymphokine and cytokine research 1994;13(4):253-8.
1994: Jo Van Damme; Paul Proost; Willy Put; S Arens; Jean-Pierre Lenaerts; René Conings; Ghislain Opdenakker; Hubertine Heremans; An D Billiau
Induction of monocyte chemotactic proteins MCP-1 and MCP-2 in human fibroblasts and leukocytes by cytokines and cytokine inducers. Chemical synthesis of MCP-2 and development of a specific RIA.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(11):5495-502.
1994: Hubertine Heremans; Chris Dillen; Jo Van Damme; An D Billiau
Essential role for natural killer cells in the lethal lipopolysaccharide-induced Shwartzman-like reaction in mice.
European journal of immunology 1994;24(5):1155-60.
1994: F Vandekerckhove; A Darji; M T Rivera; Y Carlier; Bernard Vray; An D Billiau; P De Baetselier
Modulation of T-cell responsiveness during Trypanosoma cruzi infection: analysis in different lymphoid compartments.
Parasite immunology 1994;16(2):77-85.
1994: Koen Vandenbroeck; Pierre Fiten; Ghislain Opdenakker; An D Billiau
Two distinct interleukin-1 beta genes in the pig genome.
Immunogenetics 1994;40(1):82.
1993: K Gijbels; Paul Proost; S Masure; Herwig Carton; An D Billiau; Ghislain Opdenakker
Gelatinase B is present in the cerebrospinal fluid during experimental autoimmune encephalomyelitis and cleaves myelin basic protein.
Journal of neuroscience research 1993;36(4):432-40.
1993: Koen Vandenbroeck; Pierre Fiten; E Beuken; E Martens; A Janssen; Jo Van Damme; Ghislain Opdenakker; An D Billiau
Gene sequence, cDNA construction, expression in Escherichia coli and genetically approached purification of porcine interleukin-1 beta.
European journal of biochemistry / FEBS 1993;217(1):45-52.
1993: Paul Proost; Anja Wuyts; René Conings; Jean-Pierre Lenaerts; An D Billiau; Ghislain Opdenakker; Jo Van Damme
Human and bovine granulocyte chemotactic protein-2: complete amino acid sequence and functional characterization as chemokines.
Biochemistry 1993;32(38):10170-7.
1993: Patrick Matthys; Chris Dillen; Paul Proost; Hubertine Heremans; Jo Van Damme; An D Billiau
Modification of the anti-CD3-induced cytokine release syndrome by anti-interferon-gamma or anti-interleukin-6 antibody treatment: protective effects and biphasic changes in blood cytokine levels.
European journal of immunology 1993;23(9):2209-16.
1993: E Martens; Chris Dillen; Willy Put; Hubertine Heremans; Jo Van Damme; An D Billiau
Increased circulating interleukin-6 (IL-6) activity in endotoxin-challenged mice pretreated with anti-IL-6 antibody is due to IL-6 accumulated in antigen-antibody complexes.
European journal of immunology 1993;23(8):2026-9.
1993: Koen Vandenbroeck; E Martens; S D'Andrea; An D Billiau
Refolding and single-step purification of porcine interferon-gamma from Escherichia coli inclusion bodies. Conditions for reconstitution of dimeric IFN-gamma.
European journal of biochemistry / FEBS 1993;215(2):481-6.
1993: Guy Froyen; Isabelle Ronsse; An D Billiau
Bacterial expression of a single-chain antibody fragment (SCFV) that neutralizes the biological activity of human interferon-gamma.
Molecular immunology 1993;30(9):805-12.
1993: R Dijkmans; F Cornette; S Kreps; E Martens; J Vankerkom; Max Mergeay; An D Billiau
Synergistic toxicity of IFN-gamma-producing Escherichia coli K12 cells.
Microbial releases : viruses, bacteria, fungi 1993;2(1):23-8.
1993: LM Kuschnaroff; Hubertine Heremans; Chris Dillen; Patrick Matthys; An D Billiau; Michel Vandeputte; Mark Waer
Role of interferon-gamma in the induction of clonal deletion after injection of staphylococcal enterotoxin B.
Transplantation proceedings 1993;25(1 Pt 1):317-8.
1993: Paul Proost; C De Wolf-Peeters; René Conings; Ghislain Opdenakker; An D Billiau; Jo Van Damme
Identification of a novel granulocyte chemotactic protein (GCP-2) from human tumor cells. In vitro and in vivo comparison with natural forms of GRO, IP-10, and IL-8.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(3):1000-10.
1993: Hugo Vankelecom; Patrick Matthys; Jo Van Damme; Hubertine Heremans; An D Billiau; Carl Denef
Immunocytochemical evidence that S-100-positive cells of the mouse anterior pituitary contain interleukin-6 immunoreactivity.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1993;41(2):151-6.
1993: Jo Van Damme; Paul Proost; Jean-Pierre Lenaerts; René Conings; Ghislain Opdenakker; An D Billiau
Monocyte chemotactic proteins related to human MCP-1.
Advances in experimental medicine and biology 1993;351():111-8.
1992: Hubertine Heremans; Chris Dillen; Willy Put; Jo Van Damme; An D Billiau
Protective effect of anti-interleukin (IL)-6 antibody against endotoxin, associated with paradoxically increased IL-6 levels.
European journal of immunology 1992;22(9):2395-401.
1992: An D Billiau; Patrick Matthys
Interferon-gamma, more of a cachectin than tumor necrosis factor.
Cytokine 1992;4(4):259-63.
1992: Hugo Vankelecom; Maria Andries; An D Billiau; Carl Denef
Evidence that folliculo-stellate cells mediate the inhibitory effect of interferon-gamma on hormone secretion in rat anterior pituitary cell cultures.
Endocrinology 1992;130(6):3537-46.
1991: An D Billiau; F Vandekerckhove
Cytokines and their interactions with other inflammatory mediators in the pathogenesis of sepsis and septic shock.
European journal of clinical investigation 1991;21(6):559-73.
1991: R Dijkmans; An D Billiau
Interferon-gamma/lipopolysaccharide-treated mouse embryonic fibroblasts are killed by a glycolysis/L-arginine-dependent process accompanied by depression of mitochondrial respiration.
European journal of biochemistry / FEBS 1991;202(1):151-9.
1991: Koen Vandenbroeck; R Dijkmans; Arthur Van Aerschot; An D Billiau
Engineering by PCR-based exon amplification of the genomic porcine interferon-gamma DNA for expression in Escherichia coli.
Biochemical and biophysical research communications 1991;180(3):1408-15.
1991: Patrick Matthys; R Dijkmans; Paul Proost; J Van Damme; Hubertine Heremans; H Sobis; An D Billiau
Severe cachexia in mice inoculated with interferon-gamma-producing tumor cells.
International journal of cancer. Journal international du cancer 1991;49(1):77-82.
1991: F Vandekerckhove; Ghislain Opdenakker; Marc Van Ranst; Jean-Pierre Lenaerts; Willy Put; An D Billiau; Jo Van Damme
Bradykinin induces interleukin-6 and synergizes with interleukin-1.
Lymphokine and cytokine research 1991;10(4):285-9.
1991: Marc Van Ranst; Akira Fuse; H Sobis; W De Meurichy; S M Syrjänen; An D Billiau; Ghislain Opdenakker
A papillomavirus related to HPV type 13 in oral focal epithelial hyperplasia in the pygmy chimpanzee.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1991;20(7):325-31.
1991: Ghislain Opdenakker; S Masure; Paul Proost; An D Billiau; Jo Van Damme
Natural human monocyte gelatinase and its inhibitor.
FEBS letters 1991;284(1):73-8.
1991: F Torrico; H Heremans; M T Rivera; E Van Marck; An D Billiau; Y Carlier
Endogenous IFN-gamma is required for resistance to acute Trypanosoma cruzi infection in mice.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(10):3626-32.
1991: R Dijkmans; E Martens; E Beuken; F Cornette; Chris Dillen; Hubertine Heremans; D Boraschi; An D Billiau
Murine interferon-gamma/interleukin-1 fusion proteins used as antigens for the generation of hybridomas producing monoclonal anti-interleukin-1 antibodies.
Cytokine 1991;3(2):134-40.
1991: B J Foets; Joost J van den Oord; An D Billiau; Jo Van Damme; Luc Missotten
Heterogeneous induction of major histocompatibility complex class II antigens on corneal endothelium by interferon-gamma.
Investigative ophthalmology & visual science 1991;32(2):341-5.
1991: Peter Carmeliet; Hugo Vankelecom; Jo Van Damme; An D Billiau; Carl Denef
Release of interleukin-6 from anterior pituitary cell aggregates: developmental pattern and modulation by glucocorticoids and forskolin.
Neuroendocrinology 1991;53(1):29-34.
1991: Patrick Matthys; Hubertine Heremans; G Opdenakker; An D Billiau
Anti-interferon-gamma antibody treatment, growth of Lewis lung tumours in mice and tumour-associated cachexia.
European journal of cancer (Oxford, England : 1990) 1991;27(2):182-7.
1990: R Dijkmans; John W M Creemers; An D Billiau
Chicken macrophage activation by interferon: do birds lack the molecular homologue of mammalian interferon-gamma?
Veterinary immunology and immunopathology 1990;26(4):319-32.
1990: An D Billiau; R Dijkmans
Interferon-gamma: mechanism of action and therapeutic potential.
Biochemical pharmacology 1990;40(7):1433-9.
1990: S Masure; An D Billiau; Jo Van Damme; Ghislain Opdenakker
Human hepatoma cells produce an 85 kDa gelatinase regulated by phorbol 12-myristate 13-acetate.
Biochimica et biophysica acta 1990;1054(3):317-25.
1990: Jo Van Damme; M Rampart; René Conings; B Decock; N Van Osselaer; J Willems; An D Billiau
The neutrophil-activating proteins interleukin 8 and beta-thromboglobulin: in vitro and in vivo comparison of NH2-terminally processed forms.
European journal of immunology 1990;20(9):2113-8.
1990: R Dijkmans; Koen Vandenbroeck; E Beuken; An D Billiau; D Roger; V Koen; B Erik; B Alfons
Sequence of the porcine interferon-gamma (IFN-gamma) gene.
Nucleic acids research 1990;18(14):4259.
1990: Hugo Vankelecom; Peter Carmeliet; Hubertine Heremans; Jo Van Damme; R Dijkmans; An D Billiau; Carl Denef
Interferon-gamma inhibits stimulated adrenocorticotropin, prolactin, and growth hormone secretion in normal rat anterior pituitary cell cultures.
Endocrinology 1990;126(6):2919-26.
1990: Hubertine Heremans; Jo Van Damme; Chris Dillen; R Dijkmans; An D Billiau
Interferon gamma, a mediator of lethal lipopolysaccharide-induced Shwartzman-like shock reactions in mice.
The Journal of experimental medicine 1990;171(6):1853-69.
1990: B Decock; René Conings; Jean-Pierre Lenaerts; An D Billiau; Jo Van Damme
Identification of the monocyte chemotactic protein from human osteosarcoma cells and monocytes: detection of a novel N-terminally processed form.
Biochemical and biophysical research communications 1990;167(3):904-9.
1990: K Gijbels; Jo Van Damme; Paul Proost; Willy Put; Herwig Carton; An D Billiau
Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitis.
European journal of immunology 1990;20(1):233-5.
1990: Y Cabeza-Arvelaiz; Chris Dillen; Hubertine Heremans; Jo Van Damme; J Cailleau; An D Billiau; Ghislain Opdenakker
Cholera and pertussis exotoxins protect mice against the lethal Schwartzman reaction and antagonize the effects of lipopolysaccharide on second messenger systems.
Lymphokine research 1990;9(2):125-35.
1990: R Dijkmans; M Tobback; E Beuken; Jo Van Damme; An D Billiau
Molecular cloning of the baboon interferon-gamma cDNA.
Lymphokine research 1990;9(3):345-54.
1990: R Dijkmans; J Van Damme; F Cornette; Hubertine Heremans; An D Billiau
Bacterial lipopolysaccharide potentiates gamma interferon-induced cytotoxicity for normal mouse and rat fibroblasts.
Infection and immunity 1990;58(1):32-6.
1989: Jo Van Damme; B Decock; Jean-Pierre Lenaerts; René Conings; R Bertini; A Mantovani; An D Billiau
Identification by sequence analysis of chemotactic factors for monocytes produced by normal and transformed cells stimulated with virus, double-stranded RNA or cytokine.
European journal of immunology 1989;19(12):2367-73.
1989: Jo Van Damme; B Decock; René Conings; Jean-Pierre Lenaerts; Ghislain Opdenakker; An D Billiau
The chemotactic activity for granulocytes produced by virally infected fibroblasts is identical to monocyte-derived interleukin 8.
European journal of immunology 1989;19(7):1189-94.
1989: Jo Van Damme; J Van Beeumen; René Conings; B Decock; An D Billiau
Purification of granulocyte chemotactic peptide/interleukin-8 reveals N-terminal sequence heterogeneity similar to that of beta-thromboglobulin.
European journal of biochemistry / FEBS 1989;181(2):337-44.
1989: Hugo Vankelecom; Peter Carmeliet; Jo Van Damme; An D Billiau; Carl Denef
Production of interleukin-6 by folliculo-stellate cells of the anterior pituitary gland in a histiotypic cell aggregate culture system.
Neuroendocrinology 1989;49(1):102-6.
1989: Jo Van Damme; M R Schaafsma; René Conings; Jean-Pierre Lenaerts; Willy Put; An D Billiau; W E Fibbe
Interleukin 1 induces different cytokines in human fibroblasts.
Lymphokine research 1989;8(3):289-92.
1989: Jo Van Damme; M R Schaafsma; W E Fibbe; J H Falkenburg; Ghislain Opdenakker; An D Billiau
Simultaneous production of interleukin 6, interferon-beta and colony-stimulating activity by fibroblasts after viral and bacterial infection.
European journal of immunology 1989;19(1):163-8.
1989: Hubertine Heremans; Chris Dillen; R Dijkmans; G Grau; An D Billiau
The role of cytokines in various animal models of inflammation.
Lymphokine research 1989;8(3):329-33.
1989: R Dijkmans; B Decock; Hubertine Heremans; Jo Van Damme; An D Billiau
Interferon-gamma is cytotoxic for normal mouse fibroblasts: enhancement by tumor necrosis factor and interleukin 1.
Lymphokine research 1989;8(1):25-34.
1988: Jan L Ceuppens; M L Baroja; K Lorre; Jo Van Damme; An D Billiau
Human T cell activation with phytohemagglutinin. The function of IL-6 as an accessory signal.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(11):3868-74.
1988: R Dijkmans; An D Billiau
Interferon gamma: a master key in the immune system.
Current opinion in immunology 1988;1(2):269-74.
1988: Ghislain Opdenakker; F Bosman; B Decock; Y Cabeza-Arvelaiz; Jo Van Damme; An D Billiau
Heterogeneity of human tissue-type plasminogen activator.
FEBS letters 1988;238(1):129-34.
1988: M L Baroja; Jan L Ceuppens; Jo Van Damme; An D Billiau
Cooperation between an anti-T cell (anti-CD28) monoclonal antibody and monocyte-produced IL-6 in the induction of T cell responsiveness to IL-2.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(5):1502-7.
1988: Guido Verhoeven; J Cailleau; J Van Damme; An D Billiau
Interleukin-1 stimulates steroidogenesis in cultured rat Leydig cells.
Molecular and cellular endocrinology 1988;57(1-2):51-60.
1988: Jo Van Damme; J Van Beeumen; Ghislain Opdenakker; An D Billiau
A novel, NH2-terminal sequence-characterized human monokine possessing neutrophil chemotactic, skin-reactive, and granulocytosis-promoting activity.
The Journal of experimental medicine 1988;167(4):1364-76.
1988: Jo Van Damme; J Van Beeumen; B Decock; J Van Snick; Marc De Ley; An D Billiau
Separation and comparison of two monokines with lymphocyte-activating factor activity: IL-1 beta and hybridoma growth factor (HGF). Identification of leukocyte-derived HGF as IL-6.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(5):1534-41.
1988: An D Billiau; Hubertine Heremans; F Vandekerckhove; R Dijkmans; H Sobis; E Meulepas; Herwig Carton
Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(5):1506-10.
1987: An D Billiau; Hubertine Heremans; F Vandekerckhove; Chris Dillen
Anti-interferon-gamma antibody protects mice against the generalized Shwartzman reaction.
European journal of immunology 1987;17(12):1851-4.
1987: Jo Van Damme; S Cayphas; J Van Snick; René Conings; Willy Put; Jean-Pierre Lenaerts; Richard J Simpson; An D Billiau
Purification and characterization of human fibroblast-derived hybridoma growth factor identical to T-cell-derived B-cell stimulatory factor-2 (interleukin-6).
European journal of biochemistry / FEBS 1987;168(3):543-50.
1987: S Cayphas; Jo Van Damme; Anne Vink; Richard J Simpson; An D Billiau; J Van Snick
Identification of an interleukin HP1-like plasmacytoma growth factor produced by L cells in response to viral infection.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(9):2965-9.
1987: An D Billiau
Interferons and inflammation.
Journal of interferon research 1987;7(5):559-67.
1987: An D Billiau
Redefining interferon: the interferon-like antiviral effects of certain cytokines (interleukin-1, interferon-beta 2, interferon-gamma) may be indirect or side effects.
Antiviral research 1987;8(2):55-70.
1987: Hubertine Heremans; R Dijkmans; H Sobis; F Vandekerckhove; An D Billiau
Regulation by interferons of the local inflammatory response to bacterial lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(12):4175-9.
1987: H Heremans; An D Billiau; Jean-Paul Coutelier; P De Somer
The inhibition of endotoxin-induced local inflammation by LDH virus or LDH virus-infected tumors is mediated by interferon.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1987;185(1):6-15.
1987: Jo Van Damme; G Opdenakker; Richard J Simpson; M R Rubira; S Cayphas; Anne Vink; An D Billiau; J Van Snick
Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.
The Journal of experimental medicine 1987;165(3):914-9.
1987: Jo Van Damme; S Cayphas; G Opdenakker; An D Billiau; J Van Snick
Interleukin 1 and poly(rI).poly(rC) induce production of a hybridoma growth factor by human fibroblasts.
European journal of immunology 1987;17(1):1-7.
1987: An D Billiau
The interferon-interleukin 1 connection.
Interferon 1987;9():91-111.
1985: G Opdenakker; An D Billiau; G Volckaert; P de Somer
Determination of tissue-type plasminogen-activator mRNA in human and non-human cell lines by dot-blot hybridization.
The Biochemical journal 1985;231(2):309-13.
1985: J Van Damme; M De Ley; G Opdenakker; An D Billiau; P De Somer; J Van Beeumen
Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1.
Nature 1985;314(6008):266-8.
1985: G Vervliet; H Carton; An D Billiau
Interferon-gamma production by peripheral blood leucocytes from patients with multiple sclerosis and other neurological diseases.
Clinical and experimental immunology 1985;59(2):391-7.
1985: R Dijkmans; G Volckaert; J Van Damme; M De Ley; An D Billiau; P De Somer
Molecular cloning of murine interferon gamma (MuIFN-gamma) cDNA and its expression in heterologous mammalian cells.
Journal of interferon research 1985;5(3):511-20.
1984: G Vervliet; H Carton; E Meulepas; An D Billiau
Interferon production by cultured peripheral leucocytes of MS patients.
Clinical and experimental immunology 1984;58(1):116-26.
1983: J Van Damme; An D Billiau; M De Ley; P De Somer
An interferon-beta-like or interferon-inducing protein released by mitogen-stimulated human leukocytes.
The Journal of general virology 1983;64 (Pt 8)():1819-22.
1983: G Vervliet; H Claeys; H Van Haver; H Carton; C Vermylen; E Meulepas; An D Billiau
Interferon production and natural killer (NK) activity in leukocyte cultures from multiple sclerosis patients.
Journal of the neurological sciences 1983;60(1):137-50.
1982: H Weening; A Fuse; G Opdenakker; J Van Damme; M De Ley; An D Billiau
Messenger RNA of human immune interferon: isolation and partial characterization.
Biochemical and biophysical research communications 1982;104(1):6-13.
1982: G Opdenakker; H Weening; D Collen; An D Billiau; P de Somer
Messenger RNA for human tissue plasminogen activator.
European journal of biochemistry / FEBS 1982;121(2):269-74.
1981: J Van Damme; M De Ley; H Claeys; An D Billiau; C Vermylen; P De Somer
Interferon induced in human leukocytes by concanavalin A: isolation and characterization of gamma- and beta-type components.
European journal of immunology 1981;11(11):937-42.
1981: An D Billiau; J Bloemmen; M Bogaerts; H Claeys; J Van Damme; M De Ley; P de Somer; A Drochmans; H Heremans; A Kriel; J Schetz; Guido Tricot; C Vermylen; R Verwilghen; M Waer
Interferon therapy in multiple myeloma: failure of human fibroblast interferon administration to the course of light chain disease.
European journal of cancer & clinical oncology 1981;17(8):875-82.
1981: J W Heine; J Van Damme; M de Ley; An D Billiau; P de Somer
Purification of human fibroblast interferon by zinc chelate chromatography.
The Journal of general virology 1981;54(Pt 1):47-56.
1981: An D Billiau; J Van Damme; M De Ley; P De Somer
Characteristics of HuIFN-gamma and HuIFN-beta induced by mitogenic stimulation of human leukocytes.
Texas reports on biology and medicine 1981;41():184-91.
1980: M de Ley; J van Damme; H Claeys; H Weening; J W Heine; An D Billiau; C Vermylen; P de Somer
Interferon induced in human leukocytes by mitogens: production, partial purification and characterization.
European journal of immunology 1980;10(11):877-83.
1980: H Heremans; An D Billiau; P De Somer
Interferon in experimental viral infections in mice: tissue interferon levels resulting from the virus infection and from exogenous interferon therapy.
Infection and immunity 1980;30(2):513-22.
1980: An D Billiau; J W Heine; J Van Damme; H Heremans; P De Somer
Tolerability of pure fibroblast interferon in man.
Annals of the New York Academy of Sciences 1980;350():374-5.
1970: An D Billiau; E Schonne; L Eyckmans; P De Somer
Interferon Induction and Resistance to Virus Infection in Mice Infected with Brucella abortus.
Infection and immunity 1970;2(6):698-704.