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Orit Rozenblatt-Rosen

Research Profile

Chemicals & Drugs

Anatomy

Cell Line

Procedures

Chromatin Immunoprecipitation

Physiology

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Mouse

Genes & Molecular Sequences

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Publications

TOP 3
Jingwei Cheng; Paul X Nghiem; Kelly G Paulson; Orit Rozenblatt-Rosen; James A DeCaprio
Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities.
Debrah A Fine; Laurence Florens; Luxuan Guo; David E Hill; Robert L James; Anna Korkhin; Larisa Litovchick; Jarrod A Marto; Megha Padi; Orit Rozenblatt-Rosen; Soundarapandian Velmurgan; Marc Vidal; Michael P Washburn; Rosa Yoon; Ying Zhang; G Adelmant; Christian Berrios; Michael A Calderwood; Jingwei Cheng; Michael E Cusick; James A DeCaprio
Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor.
Atsushi Takahashi; Ryouhei Tsutsumi; Taewoo Cho; Minerva Fernandez; Robert Karisch; Ippei Kikuchi; Matthew Meyerson; Benjamin G Neel; Chikashi Obuse; Naomi Ohnishi; Orit Rozenblatt-Rosen; Yasuhiro Saito; Azadeh Seidi; Masanori Hatakeyama
SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver.

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All Publications

2013: Jingwei Cheng; Paul X Nghiem; Kelly G Paulson; Orit Rozenblatt-Rosen; James A DeCaprio
Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities.
Journal of virology 2013;87(11):6118-26.
2012: Debrah A Fine; Laurence Florens; Luxuan Guo; David E Hill; Robert L James; Anna Korkhin; Larisa Litovchick; Jarrod A Marto; Megha Padi; Orit Rozenblatt-Rosen; Soundarapandian Velmurgan; Marc Vidal; Michael P Washburn; Rosa Yoon; Ying Zhang; G Adelmant; Christian Berrios; Michael A Calderwood; Jingwei Cheng; Michael E Cusick; James A DeCaprio
Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor.
PLoS pathogens 2012;8(10):e1002949.
2011: Atsushi Takahashi; Ryouhei Tsutsumi; Taewoo Cho; Minerva Fernandez; Robert Karisch; Ippei Kikuchi; Matthew Meyerson; Benjamin G Neel; Chikashi Obuse; Naomi Ohnishi; Orit Rozenblatt-Rosen; Yasuhiro Saito; Azadeh Seidi; Masanori Hatakeyama
SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver.
Molecular cell 2011;43(1):45-56.
2011: Takashi Nagaike; Charlotte Logan; Ikuko Hotta; Orit Rozenblatt-Rosen; Matthew Meyerson; James L Manley
Transcriptional activators enhance polyadenylation of mRNA precursors.
Molecular cell 2011;41(4):409-18.
2011: Joshua Francis; Wenchu Lin; Orit Rozenblatt-Rosen; Matthew Meyerson
The menin tumor suppressor protein is phosphorylated in response to DNA damage.
PloS one 2011;6(1):e16119.
2009: Orit Rozenblatt-Rosen; Takashi Nagaike; Joshua M Francis; Syuzo Kaneko; Karen A Glatt; Christina M Hughes; Thomas LaFramboise; James L Manley; Matthew Meyerson
The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(3):755-60.
2007: Syuzo Kaneko; Orit Rozenblatt-Rosen; Matthew Meyerson; James L Manley
The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination.
Genes & development 2007;21(14):1779-89.
2006: Laura E MacConaill; Christina M Hughes; Orit Rozenblatt-Rosen; Suraj Nannepaga; Matthew Meyerson
Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583.
Molecular cancer research : MCR 2006;4(10):793-801.
2006: Ian Davis; Jessica J Kim; Fatih Ozsolak; Hans R Widlund; Orit Rozenblatt-Rosen; Scott R Granter; Jinyan Du; Jonathan A Fletcher; Christopher T Denny; Stephen L Lessnick; W Marston Linehan; Andrew L Kung; David E Fisher
Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.
Cancer cell 2006;9(6):473-84.
2005: Akihiko Yokoyama; Tim C P Somervaille; Kevin S Smith; Orit Rozenblatt-Rosen; Matthew Meyerson; Michael L Cleary
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.
Cell 2005;123(2):207-18.
2005: Satyajit K Karnik; Christina M Hughes; Xueying Gu; Orit Rozenblatt-Rosen; Graeme W McLean; Yue Xiong; Matthew Meyerson; Seung K Kim
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14659-64.
2005: Thomas A Milne; Christina M Hughes; Ricardo Lloyd; Zhaohai Yang; Orit Rozenblatt-Rosen; Yali Dou; Robert W Schnepp; Cynthia Krankel; Virginia A LiVolsi; Denise Gibbs; Xianxin Hua; Robert G Roeder; Matthew Meyerson; Jay L Hess
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):749-54.
2005: Orit Rozenblatt-Rosen; Christina M Hughes; Suraj J Nannepaga; Kalai Selvi Shanmugam; Terry D Copeland; Tad Guszczynski; James Resau; Matthew Meyerson
The parafibromin tumor suppressor protein is part of a human Paf1 complex.
Molecular and cellular biology 2005;25(2):612-20.
2004: Christina M Hughes; Orit Rozenblatt-Rosen; Thomas A Milne; Terry D Copeland; Stuart S Levine; Jeffrey C Lee; David Hayes; Kalai Selvi Shanmugam; Arindam Bhattacharjee; Christine A Biondi; Graham F Kay; Nicholas K Hayward; Jay L Hess; Matthew Meyerson
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus.
Molecular cell 2004;13(4):587-97.
2004: Peter C Scacheri; Orit Rozenblatt-Rosen; Natasha J Caplen; Tyra G Wolfsberg; Lowell Umayam; Jeffrey C Lee; Christina M Hughes; Kalai Selvi Shanmugam; Arindam Bhattacharjee; Matthew Meyerson; Francis S Collins
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):1892-7.
2002: Orit Rozenblatt-Rosen; Efrat Mosonego-Ornan; Einat Sadot; Liora Madar-Shapiro; Yuri Sheinin; Doron Ginsberg; Avner Yayon
Induction of chondrocyte growth arrest by FGF: transcriptional and cytoskeletal alterations.
Journal of cell science 2002;115(Pt 3):553-62.
2000: Tanya Rozovskaia; Orit Rozenblatt-Rosen; Yurii Sedkov; D Burakov; T Yano; Tatsuya Nakamura; S Petruck; Levana Ben-Simchon; Carlo M Croce; Alexander Mazo; Eli Canaani
Self-association of the SET domains of human ALL-1 and of Drosophila TRITHORAX and ASH1 proteins.
Oncogene 2000;19(3):351-7.
1999: Tanya Rozovskaia; Sergei Tillib; S Smith; Yurii Sedkov; Orit Rozenblatt-Rosen; Svetlana Petruk; T Yano; Tatsuya Nakamura; Levana Ben-Simchon; J Gildea; Carlo M Croce; A Shearn; Eli Canaani; Alexander Mazo
Trithorax and ASH1 interact directly and associate with the trithorax group-responsive bxd region of the Ultrabithorax promoter.
Molecular and cellular biology 1999;19(9):6441-7.
1998: Orit Rozenblatt-Rosen; Tanya Rozovskaia; D Burakov; Yurii Sedkov; Sergei Tillib; Janna Blechman; Tatsuya Nakamura; Carlo M Croce; Alexander Mazo; Eli Canaani
The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4152-7.