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Gerald Rubin

Research Profile

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Concepts & Ideas

Molecular Sequence Data

Physiology

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Cloning, Molecular

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Publications

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Pavel Tomancak; Benjamin P Berman; Amy Beaton; Richard Weiszmann; Elaine Kwan; Volker Hartenstein; Susan E Celniker; Gerald M Rubin
Global analysis of patterns of gene expression during Drosophila embryogenesis.
Xiaoli Qin; Soyeon Ahn; Terence P Speed; Gerald M Rubin
Global analyses of mRNA translational control during early Drosophila embryogenesis.
Mark Yandell; Chris Mungall; Chris Smith; Simon Prochnik; Joshua S Kaminker; George Hartzell; Suzanna Lewis; Gerald M Rubin
Large-scale trends in the evolution of gene structures within 11 animal genomes.

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All Publications

2007: Pavel Tomancak; Benjamin P Berman; Amy Beaton; Richard Weiszmann; Elaine Kwan; Volker Hartenstein; Susan E Celniker; Gerald M Rubin
Global analysis of patterns of gene expression during Drosophila embryogenesis.
Genome biology 2007;8(7):R145.
2007: Xiaoli Qin; Soyeon Ahn; Terence P Speed; Gerald M Rubin
Global analyses of mRNA translational control during early Drosophila embryogenesis.
Genome biology 2007;8(4):R63.
2006: Mark Yandell; Chris Mungall; Chris Smith; Simon Prochnik; Joshua S Kaminker; George Hartzell; Suzanna Lewis; Gerald M Rubin
Large-scale trends in the evolution of gene structures within 11 animal genomes.
PLoS computational biology 2006;2(3):e15.
2005: A Aziz Aboobaker; Pavel Tomancak; Nipam Patel; Gerald M Rubin; Eric C Lai
Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(50):18017-22.
2005: Liisa Myllykangas; Jaana Tyynelä; Andrea Page-McCaw; Gerald M Rubin; Matti Haltia; Mel B Feany
Cathepsin D-deficient Drosophila recapitulate the key features of neuronal ceroid lipofuscinoses.
Neurobiology of disease 2005;19(1-2):194-9.
2005: Eric C Lai; Fabrice Roegiers; Xiaoli Qin; Yuh Nung Jan; Gerald M Rubin
The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta.
Development (Cambridge, England) 2005;132(10):2319-32.
2005: Jonathan L Tupy; Adina M Bailey; Gina Dailey; Martha Evans-Holm; Christian W Siebel; Sima Misra; Susan E Celniker; Gerald M Rubin
Identification of putative noncoding polyadenylated transcripts in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(15):5495-500.
2005: Mark Yandell; Adina M Bailey; Sima Misra; ShengQiang Shu; Colin Wiel; Martha Evans-Holm; Susan E Celniker; Gerald M Rubin
A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1566-71.
2004: Hugo J Bellen; Robert W Levis; Guochun Liao; Yuchun He; Joseph W Carlson; Garson Tsang; Martha Evans-Holm; P Robin Hiesinger; Karen L Schulze; Gerald M Rubin; Roger A Hoskins; ALLAN SPRADLING
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes.
Genetics 2004;167(2):761-81.
2004: Eric C Lai; Colin Wiel; Gerald M Rubin
Complementary miRNA pairs suggest a regulatory role for miRNA:miRNA duplexes.
RNA (New York, N.Y.) 2004;10(2):171-5.
2004: Michael H Brodsky; Brian T Weinert; Garson Tsang; Yikang S Rong; Nadine McGinnis; Kent G Golic; Donald C Rio; Gerald M Rubin
Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage.
Molecular and cellular biology 2004;24(3):1219-31.
2004: Benjamin P Berman; Barret D Pfeiffer; Todd R Laverty; Steven L Salzberg; Gerald M Rubin; Michael B Eisen; Susan E Celniker
Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura.
Genome biology 2004;5(9):R61.
2003: Julia Serano; Gerald M Rubin
The Drosophila synaptotagmin-like protein bitesize is required for growth and has mRNA localization sequences within its open reading frame.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13368-73.
2003: Koenraad K Norga; Marjorie C Gurganus; Christy L Dilda; Akihiko Yamamoto; Richard F Lyman; Prajal H Patel; Gerald M Rubin; Roger A Hoskins; Trudy F C Mackay; Hugo J Bellen
Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development.
Current biology : CB 2003;13(16):1388-96.
2003: Antonio Carvalho; Maria Dulcetti Vibranovski; Joseph W Carlson; Susan E Celniker; Roger A Hoskins; Gerald M Rubin; Granger Sutton; Mark D Adams; Eugene W Myers; andrew clark
Y chromosome and other heterochromatic sequences of the Drosophila melanogaster genome: how far can we go?
Genetica 2003;117(2-3):227-37.
2003: Susan E Celniker; Gerald M Rubin
The Drosophila melanogaster genome.
Annual review of genomics and human genetics 2003;4():89-117.
2003: Eric C Lai; Pavel Tomancak; Robert W Williams; Gerald M Rubin
Computational identification of Drosophila microRNA genes.
Genome biology 2003;4(7):R42.
2003: Andrea Page-McCaw; Julia Serano; Joshua M Santé; Gerald M Rubin
Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development.
Developmental cell 2003;4(1):95-106.
2002: Mark Stapleton; Guochun Liao; Peter Brokstein; Ling Hong; piero carninci; Toshiyuki Shiraki; Yoshihide Hayashizaki; Mark Champe; Joanne Pacleb; Ken Wan; Charles Yu; Joe Carlson; Reed George; Susan E Celniker; Gerald M Rubin
The Drosophila gene collection: identification of putative full-length cDNAs for 70% of D. melanogaster genes.
Genome research 2002;12(8):1294-300.
2002: Yikang S Rong; Simon W Titen; Heng B Xie; Mary M Golic; Michael J Bastiani; Pradip K Bandyopadhyay; Baldomero M Olivera; Michael H Brodsky; Gerald M Rubin; Kent G Golic
Targeted mutagenesis by homologous recombination in D. melanogaster.
Genes & development 2002;16(12):1568-81.
2002: Ennio De Gregorio; Paul Spellman; Phoebe Tzou; Gerald M Rubin; Bruno Lemaitre
The Toll and Imd pathways are the major regulators of the immune response in Drosophila.
The EMBO journal 2002;21(11):2568-79.
2002: Robert W Williams; Gerald M Rubin
ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6889-94.
2002: Kathleen M C Sullivan; Gerald M Rubin
The Ca(2+)-calmodulin-activated protein phosphatase calcineurin negatively regulates EGF receptor signaling in Drosophila development.
Genetics 2002;161(1):183-93.
2002: Benjamin P Berman; Yutaka Nibu; Barret D Pfeiffer; Pavel Tomancak; Susan E Celniker; Michael Levine; Gerald M Rubin; Michael B Eisen
Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):757-62.
2002: Pavel Tomancak; Amy Beaton; Richard Weiszmann; Elaine Kwan; ShengQiang Shu; Suzanna E Lewis; Stephen Richards; Michael Ashburner; Volker Hartenstein; Susan E Celniker; Gerald M Rubin
Systematic determination of patterns of gene expression during Drosophila embryogenesis.
Genome biology 2002;3(12):RESEARCH0088.
2002: Uwe Ohler; Guo-chun Liao; Heinrich Niemann; Gerald M Rubin
Computational analysis of core promoters in the Drosophila genome.
Genome biology 2002;3(12):RESEARCH0087.
2002: Casey M Bergman; Barret D Pfeiffer; Diego E Rincón-Limas; Roger A Hoskins; Andreas Gnirke; Chris Mungall; Adrienne M Wang; Brent Kronmiller; Joanne Pacleb; Soo Park; Mark Stapleton; Ken Wan; Reed A George; Pieter J de Jong; Juan Botas; Gerald M Rubin; Susan E Celniker
Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome.
Genome biology 2002;3(12):RESEARCH0086.
2002: Roger A Hoskins; Christopher D Smith; Joseph W Carlson; Antonio Carvalho; Aaron Halpern; Joshua S Kaminker; Cameron Kennedy; Chris Mungall; Beth A Sullivan; Granger Sutton; Jiro C Yasuhara; Barbara T Wakimoto; Eugene W Myers; Susan E Celniker; Gerald M Rubin; Gary Karpen
Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.
Genome biology 2002;3(12):RESEARCH0085.
2002: Joshua S Kaminker; Casey M Bergman; Brent Kronmiller; Joe Carlson; Robert Svirskas; Sandeep Patel; Erwin Frise; David A Wheeler; Suzanna E Lewis; Gerald M Rubin; Michael Ashburner; Susan E Celniker
The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.
Genome biology 2002;3(12):RESEARCH0084.
2002: Sima Misra; Madeline A Crosby; Chris Mungall; Beverley B Matthews; Kathryn S Campbell; Pavel Hradecky; Yanmei Huang; Joshua S Kaminker; Gillian H Millburn; Simon Prochnik; Christopher D Smith; Jonathan L Tupy; Eleanor J Whitfied; Leyla Bayraktaroglu; Benjamin P Berman; Brian R Bettencourt; Susan E Celniker; Aubrey D N J de Grey; Rachel Drysdale; Nomi L Harris; John Richter; Susan Russo; Andrew J Schroeder; Sheng Qiang Shu; Mark Stapleton; Chihiro Yamada; Michael Ashburner; William M Gelbart; Gerald M Rubin; Suzanna E Lewis
Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
Genome biology 2002;3(12):RESEARCH0083.
2002: Suzanna E Lewis; S M J Searle; N Harris; M Gibson; V Lyer; J Richter; Colin Wiel; L Bayraktaroglir; Ewan Birney; Madeline A Crosby; Joshua S Kaminker; Beverley B Matthews; Simon Prochnik; C D Smithy; Jonathan L Tupy; Gerald M Rubin; Sima Misra; Chris Mungall; Michele Clamp
Apollo: a sequence annotation editor.
Genome biology 2002;3(12):RESEARCH0082.
2002: Chris Mungall; Sima Misra; Benjamin P Berman; Joe Carlson; Erwin Frise; N Harris; B Marshall; S Shu; Joshua S Kaminker; Simon Prochnik; Christopher D Smith; E Smith; Jonathan L Tupy; Colin Wiel; Gerald M Rubin; Suzanna E Lewis
An integrated computational pipeline and database to support whole-genome sequence annotation.
Genome biology 2002;3(12):RESEARCH0081.
2002: Mark Stapleton; Joe Carlson; Peter Brokstein; Charles Yu; Mark Champe; Reed George; Hannibal Guarin; Brent Kronmiller; Joanne Pacleb; Soo Park; Ken Wan; Gerald M Rubin; Susan E Celniker
A Drosophila full-length cDNA resource.
Genome biology 2002;3(12):RESEARCH0080.
2002: Paul Spellman; Gerald M Rubin
Evidence for large domains of similarly expressed genes in the Drosophila genome.
Journal of biology 2002;1(1):5.
2001: Eric C Lai; GA Deblandre; Chris Kintner; Gerald M Rubin
Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta.
Developmental cell 2001;1(6):783-94.
2001: Yong Q Zhang; A M Bailey; Heinrich Matthies; Robert Renden; Mark A. Smith; Sean Speese; Gerald M Rubin; Kendal Broadie
Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function.
Cell 2001;107(5):591-603.
2001: Ennio De Gregorio; Paul Spellman; Gerald M Rubin; Bruno Lemaitre
Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(22):12590-5.
2001: Eric C Lai; Gerald M Rubin
Neuralized is essential for a subset of Notch pathway-dependent cell fate decisions during Drosophila eye development.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(10):5637-42.
2001: Eric C Lai; Gerald M Rubin
neuralized functions cell-autonomously to regulate a subset of notch-dependent processes during adult Drosophila development.
Developmental biology 2001;231(1):217-33.
2001: Amy H Tang; TP Neufeld; Gerald M Rubin; H A Müller
Transcriptional regulation of cytoskeletal functions and segmentation by a novel maternal pair-rule gene, lilliputian.
Development (Cambridge, England) 2001;128(5):801-13.
2001: Uwe Ohler; H Niemann; Gerald M Rubin
Joint modeling of DNA sequence and physical properties to improve eukaryotic promoter recognition.
Bioinformatics (Oxford, England) 2001;17 Suppl 1():S199-206.
2000: Marc Therrien; Deborah K Morrison; AM Wong; Gerald M Rubin
A genetic screen for modifiers of a kinase suppressor of Ras-dependent rough eye phenotype in Drosophila.
Genetics 2000;156(3):1231-42.
2000: A M Huang; Gerald M Rubin
A misexpression screen identifies genes that can modulate RAS1 pathway signaling in Drosophila melanogaster.
Genetics 2000;156(3):1219-30.
2000: K M Sullivan; K Scott; Charles S Zuker; Gerald M Rubin
The ryanodine receptor is essential for larval development in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):5942-7.
2000: Michael H Brodsky; W Nordstrom; Garson Tsang; E Kwan; Gerald M Rubin; John M Abrams
Drosophila p53 binds a damage response element at the reaper locus.
Cell 2000;101(1):103-13.
2000: G C Liao; E J Rehm; Gerald M Rubin
Insertion site preferences of the P transposable element in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3347-51.
2000: Roger A Hoskins; C R Nelson; Benjamin P Berman; Todd R Laverty; Reed A George; L Ciesiolka; M Naeemuddin; A D Arenson; J Durbin; R G David; P E Tabor; M R Bailey; D R DeShazo; JJ Catanese; AG Mammoser; Kazutoyo Osoegawa; Pieter J de Jong; Susan E Celniker; Richard A Gibbs; Gerald M Rubin; Steven E Scherer
A BAC-based physical map of the major autosomes of Drosophila melanogaster.
Science (New York, N.Y.) 2000;287(5461):2271-4.
2000: Gerald M Rubin; L Hong; Peter Brokstein; Martha Evans-Holm; Erwin Frise; Mark Stapleton; D A Harvey
A Drosophila complementary DNA resource.
Science (New York, N.Y.) 2000;287(5461):2222-4.
2000: Gerald M Rubin; Edward B Lewis
A brief history of Drosophila's contributions to genome research.
Science (New York, N.Y.) 2000;287(5461):2216-8.
2000: Eugene W Myers; Granger Sutton; Arthur L Delcher; I M Dew; D P Fasulo; M J Flanigan; Saul A Kravitz; Clark Mobarry; Knut Reinert; Karin Remington; E L Anson; R A Bolanos; H H Chou; C M Jordan; Aaron L Halpern; Stefano Lonardi; E M Beasley; R C Brandon; L Chen; P J Dunn; Z Lai; Y Liang; D R Nusskern; M Zhan; Qing Zhang; X Zheng; Gerald M Rubin; Mark D Adams; J Craig Venter
A whole-genome assembly of Drosophila.
Science (New York, N.Y.) 2000;287(5461):2196-204.
2000: Michael H Brodsky; Jeff Sekelsky; Garson Tsang; R Scott Hawley; Gerald M Rubin
mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development.
Genes & development 2000;14(6):666-78.
2000: Ilaria Rebay; F Chen; Franny Hsiao; P A Kolodziej; B H Kuang; Todd R Laverty; C Suh; Matthew G Voas; A Williams; Gerald M Rubin
A genetic screen for novel components of the Ras/Mitogen-activated protein kinase signaling pathway that interact with the yan gene of Drosophila identifies split ends, a new RNA recognition motif-containing protein.
Genetics 2000;154(2):695-712.
1999: Marc Therrien; AM Wong; E Kwan; Gerald M Rubin
Functional analysis of CNK in RAS signaling.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13259-63.
1999: ALLAN SPRADLING; D Stern; A Beaton; E J Rhem; Todd R Laverty; N Mozden; S Misra; Gerald M Rubin
The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes.
Genetics 1999;153(1):135-77.
1999: Felix Karim; Gerald M Rubin
PTP-ER, a novel tyrosine phosphatase, functions downstream of Ras1 to downregulate MAP kinase during Drosophila eye development.
Molecular cell 1999;3(6):741-50.
1999: N Ito; Gerald M Rubin
gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle.
Cell 1999;96(4):529-39.
1999: AM Cacace; NR Michaud; Marc Therrien; K Mathes; Terry D Copeland; Gerald M Rubin; Deborah K Morrison
Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression.
Molecular and cellular biology 1999;19(1):229-40.
1998: Duohai Pan; Gerald M Rubin
Targeted expression of teashirt induces ectopic eyes in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15508-12.
1998: F Sauer; David A Wassarman; Gerald M Rubin; Robert Tjian
Retraction. TAF(II)s mediate activation of transcription in the Drosophila embryo.
Cell 1998;95(4):following 573.
1998: Marc Therrien; AM Wong; Gerald M Rubin
CNK, a RAF-binding multidomain protein required for RAS signaling.
Cell 1998;95(3):343-53.
1998: C C Kopczynski; Jasprina N Noordermeer; T L Serano; W Y Chen; J D Pendleton; S Lewis; Corey S Goodman; Gerald M Rubin
A high throughput screen to identify secreted and transmembrane proteins involved in Drosophila embryogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(17):9973-8.
1998: T Wolff; Gerald M Rubin
Strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila.
Development (Cambridge, England) 1998;125(6):1149-59.
1998: Pernille Rørth; K Szabo; A Bailey; Todd R Laverty; J Rehm; Gerald M Rubin; K Weigmann; M Milán; V Benes; W Ansorge; S M Cohen
Systematic gain-of-function genetics in Drosophila.
Development (Cambridge, England) 1998;125(6):1049-57.
1998: TP Neufeld; Amy H Tang; Gerald M Rubin
A genetic screen to identify components of the sina signaling pathway in Drosophila eye development.
Genetics 1998;148(1):277-86.
1998: Felix Karim; Gerald M Rubin
Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues.
Development (Cambridge, England) 1998;125(1):1-9.
1997: NR Michaud; Marc Therrien; AM Cacace; L C Edsall; S Spiegel; Gerald M Rubin; Deborah K Morrison
KSR stimulates Raf-1 activity in a kinase-independent manner.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):12792-6.
1997: Amy H Tang; TP Neufeld; E Kwan; Gerald M Rubin
PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism.
Cell 1997;90(3):459-67.
1997: Duojia Pan; Gerald M Rubin
Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis.
Cell 1997;90(2):271-80.
1997: B A Hay; R Maile; Gerald M Rubin
P element insertion-dependent gene activation in the Drosophila eye.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5195-200.
1997: Henry Chang; Gerald M Rubin
14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila.
Genes & development 1997;11(9):1132-9.
1997: Gerald M Rubin; Henry Chang; Felix Karim; Todd R Laverty; NR Michaud; Deborah K Morrison; Ilaria Rebay; Amy H Tang; Marc Therrien; David A Wassarman
Signal transduction downstream from Ras in Drosophila.
Cold Spring Harbor symposia on quantitative biology 1997;62():347-52.
1996: F Sauer; David A Wassarman; Gerald M Rubin; Robert Tjian
TAF(II)s mediate activation of transcription in the Drosophila embryo.
Cell 1996;87(7):1271-84.
1996: M M DeMille; B E Kimmel; Gerald M Rubin
A Drosophila gene regulated by rough and glass shows similarity to ena and VASP.
Gene 1996;183(1-2):103-8.
1996: D Fambrough; Duojia Pan; Gerald M Rubin; Corey S Goodman
The cell surface metalloprotease/disintegrin Kuzbanian is required for axonal extension in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13233-8.
1996: Marc Therrien; N R Michaud; Gerald M Rubin; Deborah K Morrison
KSR modulates signal propagation within the MAPK cascade.
Genes & development 1996;10(21):2684-95.
1996: Z C Lai; S D Harrison; Felix Karim; Y Li; Gerald M Rubin
Loss of tramtrack gene activity results in ectopic R7 cell formation, even in a sina mutant background.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):5025-30.
1996: Felix Karim; Henry Chang; Marc Therrien; David A Wassarman; T Laverty; Gerald M Rubin
A screen for genes that function downstream of Ras1 during Drosophila eye development.
Genetics 1996;143(1):315-29.
1996: David A Wassarman; N M Solomon; Gerald M Rubin
Pk92B: a Drosophila melanogaster protein kinase that belongs to the MEKK family.
Gene 1996;169(2):283-4.
1996: David A Wassarman; N M Solomon; Henry Chang; Felix Karim; Marc Therrien; Gerald M Rubin
Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila.
Genes & development 1996;10(3):272-8.
1995: B A Hay; David A Wassarman; Gerald M Rubin
Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death.
Cell 1995;83(7):1253-62.
1995: Marc Therrien; Henry Chang; N M Solomon; Felix Karim; David A Wassarman; Gerald M Rubin
KSR, a novel protein kinase required for RAS signal transduction.
Cell 1995;83(6):879-88.
1995: J E Treisman; Z C Lai; Gerald M Rubin
Shortsighted acts in the decapentaplegic pathway in Drosophila eye development and has homology to a mouse TGF-beta-responsive gene.
Development (Cambridge, England) 1995;121(9):2835-45.
1995: J E Treisman; P J Follette; Patrick H O'Farrell; Gerald M Rubin
Cell proliferation and DNA replication defects in a Drosophila MCM2 mutant.
Genes & development 1995;9(14):1709-15.
1995: E M O'Neill; M C Ellis; Gerald M Rubin; Robert Tjian
Functional domain analysis of glass, a zinc-finger-containing transcription factor in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(14):6557-61.
1995: Ilaria Rebay; Gerald M Rubin
Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway.
Cell 1995;81(6):857-66.
1995: S D Harrison; N Solomon; Gerald M Rubin
A genetic analysis of the 63E-64A genomic region of Drosophila melanogaster: identification of mutations in a replication factor C subunit.
Genetics 1995;139(4):1701-9.
1995: Duojia Pan; Gerald M Rubin
cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in Drosophila imaginal discs.
Cell 1995;80(4):543-52.
1995: Henry Chang; N M Solomon; David A Wassarman; Felix Karim; Marc Therrien; Gerald M Rubin; T Wolff
phyllopod functions in the fate determination of a subset of photoreceptors in Drosophila.
Cell 1995;80(3):463-72.
1995: David A Wassarman; Marc Therrien; Gerald M Rubin
The Ras signaling pathway in Drosophila.
Current opinion in genetics & development 1995;5(1):44-50.
1994: G Mardon; N M Solomon; Gerald M Rubin
dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila.
Development (Cambridge, England) 1994;120(12):3473-86.
1994: R W Carthew; T P Neufeld; Gerald M Rubin
Identification of genes that interact with the sina gene in Drosophila eye development.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11689-93.
1994: S D Harrison; Kendal Broadie; J van de Goor; Gerald M Rubin
Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission.
Neuron 1994;13(3):555-66.
1994: B A Hay; T Wolff; Gerald M Rubin
Expression of baculovirus P35 prevents cell death in Drosophila.
Development (Cambridge, England) 1994;120(8):2121-9.
1994: E M O'Neill; Ilaria Rebay; Robert Tjian; Gerald M Rubin
The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway.
Cell 1994;78(1):137-47.
1994: David A Wassarman; N M Solomon; Gerald M Rubin
The Drosophila melanogaster ribosomal S6 kinase II-encoding sequence.
Gene 1994;144(2):309-10.
1994: T Cutforth; Gerald M Rubin
Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila.
Cell 1994;77(7):1027-36.
1994: T P Neufeld; Gerald M Rubin
The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins.
Cell 1994;77(3):371-9.
1994: Henry Chang; Felix Karim; E M O'Neill; Ilaria Rebay; N M Solomon; Marc Therrien; David A Wassarman; T Wolff; Gerald M Rubin
Ras signal transduction pathway in Drosophila eye development.
Cold Spring Harbor symposia on quantitative biology 1994;59():147-53.
1993: Ulrike Heberlein; I K Hariharan; Gerald M Rubin
Star is required for neuronal differentiation in the Drosophila retina and displays dosage-sensitive interactions with Ras1.
Developmental biology 1993;160(1):51-63.
1993: M C Ellis; E M O'Neill; Gerald M Rubin
Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein.
Development (Cambridge, England) 1993;119(3):855-65.
1993: Y Hiromi; Marek Mlodzik; S R West; Gerald M Rubin; Corey S Goodman
Ectopic expression of seven-up causes cell fate changes during ommatidial assembly.
Development (Cambridge, England) 1993;118(4):1123-35.
1993: A C Hart; S D Harrison; D L Van Vactor; Gerald M Rubin; S Lawrence Zipursky
The interaction of bride of sevenless with sevenless is conserved between Drosophila virilis and Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(11):5047-51.
1993: Z C Lai; E Rushton; M Bate; Gerald M Rubin
Loss of function of the Drosophila zfh-1 gene results in abnormal development of mesodermally derived tissues.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):4122-6.
1993: T Xu; Gerald M Rubin
Analysis of genetic mosaics in developing and adult Drosophila tissues.
Development (Cambridge, England) 1993;117(4):1223-37.
1993: Ulrike Gaul; Henry Chang; T Choi; F Karim; Gerald M Rubin
Identification of ras targets using a genetic approach.
Ciba Foundation symposium 1993;176():85-92; discussion 92-5.
1992: J A Fischer-Vize; Gerald M Rubin; R Lehmann
The fat facets gene is required for Drosophila eye and embryo development.
Development (Cambridge, England) 1992;116(4):985-1000.
1992: R Feiler; R Bjornson; K Kirschfeld; D Mismer; Gerald M Rubin; D P Smith; M Socolich; Charles S Zuker
Ectopic expression of ultraviolet-rhodopsins in the blue photoreceptor cells of Drosophila: visual physiology and photochemistry of transgenic animals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(10):3862-8.
1992: M Freeman; B E Kimmel; Gerald M Rubin
Identifying targets of the rough homeobox gene of Drosophila: evidence that rhomboid functions in eye development.
Development (Cambridge, England) 1992;116(2):335-46.
1992: Z C Lai; Gerald M Rubin
Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein.
Cell 1992;70(4):609-20.
1992: M Freeman; C Klämbt; Corey S Goodman; Gerald M Rubin
The argos gene encodes a diffusible factor that regulates cell fate decisions in the Drosophila eye.
Cell 1992;69(6):963-75.
1992: J A Fischer-Vize; P D Vize; Gerald M Rubin
A unique mutation in the Enhancer of split gene complex affects the fates of the mystery cells in the developing Drosophila eye.
Development (Cambridge, England) 1992;115(1):89-101.
1992: Nicholas E Baker; Kevin Moses; D Nakahara; M C Ellis; R W Carthew; Gerald M Rubin
Mutations on the second chromosome affecting the Drosophila eye.
Journal of neurogenetics 1992;8(2):85-100.
1992: Nicholas E Baker; Gerald M Rubin
Ellipse mutations in the Drosophila homologue of the EGF receptor affect pattern formation, cell division, and cell death in eye imaginal discs.
Developmental biology 1992;150(2):381-96.
1992: Ulrike Gaul; G Mardon; Gerald M Rubin
A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase.
Cell 1992;68(6):1007-19.
1992: Marek Mlodzik; Y Hiromi; Corey S Goodman; Gerald M Rubin
The presumptive R7 cell of the developing Drosophila eye receives positional information independent of sevenless, boss and sina.
Mechanisms of development 1992;37(1-2):37-42.
1992: M E Fortini; M A Simon; Gerald M Rubin
Signalling by the sevenless protein tyrosine kinase is mimicked by Ras1 activation.
Nature 1992;355(6360):559-61.
1992: M A Simon; R W Carthew; M E Fortini; Ulrike Gaul; G Mardon; Gerald M Rubin
Signal transduction pathway initiated by activation of the sevenless tyrosine kinase receptor.
Cold Spring Harbor symposia on quantitative biology 1992;57():375-80.
1991: I K Hariharan; P T Chuang; Gerald M Rubin
Cloning and characterization of a receptor-class phosphotyrosine phosphatase gene expressed on central nervous system axons in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11266-70.
1991: T P Neufeld; R W Carthew; Gerald M Rubin
Evolution of gene position: chromosomal arrangement and sequence comparison of the Drosophila melanogaster and Drosophila virilis sina and Rh4 genes.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10203-7.
1991: I K Hariharan; R W Carthew; Gerald M Rubin
The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination.
Cell 1991;67(4):717-22.
1991: M A Simon; D D Bowtell; G S Dodson; T R Laverty; Gerald M Rubin
Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.
Cell 1991;67(4):701-16.
1991: Gerald M Rubin
Signal transduction and the fate of the R7 photoreceptor in Drosophila.
Trends in genetics : TIG 1991;7(11-12):372-7.
1991: M C Mullins; Gerald M Rubin
Isolation of temperature-sensitive mutations of the tyrosine kinase receptor sevenless (sev) in Drosophila and their use in determining its time of action.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(21):9387-91.
1991: D D Bowtell; T Lila; majid shafaee; D Hackett; Gerald M Rubin
Analysis of the enhancer element that controls expression of sevenless in the developing Drosophila eye.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(15):6853-7.
1991: M E Fortini; Gerald M Rubin
The optic lobe projection pattern of polarization-sensitive photoreceptor cells in Drosophila melanogaster.
Cell and tissue research 1991;265(1):185-91.
1991: U Heberlein; Marek Mlodzik; Gerald M Rubin
Cell-fate determination in the developing Drosophila eye: role of the rough gene.
Development (Cambridge, England) 1991;112(3):703-12.
1991: Z C Lai; M E Fortini; Gerald M Rubin
The embryonic expression patterns of zfh-1 and zfh-2, two Drosophila genes encoding novel zinc-finger homeodomain proteins.
Mechanisms of development 1991;34(2-3):123-34.
1991: M E Fortini; Z C Lai; Gerald M Rubin
The Drosophila zfh-1 and zfh-2 genes encode novel proteins containing both zinc-finger and homeodomain motifs.
Mechanisms of development 1991;34(2-3):113-22.
1991: Kevin Moses; Gerald M Rubin
Glass encodes a site-specific DNA-binding protein that is regulated in response to positional signals in the developing Drosophila eye.
Genes & development 1991;5(4):583-93.
1991: J S Heilig; M Freeman; T Laverty; K J Lee; Ana Regina Campos; Gerald M Rubin; Hermann Steller
Isolation and characterization of the disconnected gene of Drosophila melanogaster.
The EMBO journal 1991;10(4):809-15.
1991: Ulrike Heberlein; Gerald M Rubin
Star is required in a subset of photoreceptor cells in the developing Drosophila retina and displays dosage sensitive interactions with rough.
Developmental biology 1991;144(2):353-61.
1990: Nicholas E Baker; Marek Mlodzik; Gerald M Rubin
Spacing differentiation in the developing Drosophila eye: a fibrinogen-related lateral inhibitor encoded by scabrous.
Science (New York, N.Y.) 1990;250(4986):1370-7.
1990: R W Carthew; Gerald M Rubin
seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye.
Cell 1990;63(3):561-77.
1990: Marek Mlodzik; Nicholas E Baker; Gerald M Rubin
Isolation and expression of scabrous, a gene regulating neurogenesis in Drosophila.
Genes & development 1990;4(11):1848-61.
1990: Ulrike Heberlein; Gerald M Rubin
Structural and functional comparisons of the Drosophila virilis and Drosophila melanogaster rough genes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5916-20.
1990: majid shafaee; D D Bowtell; Gerald M Rubin
Comparison of the sevenless genes of Drosophila virilis and Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(14):5351-3.
1990: K R Jones; Gerald M Rubin
Molecular analysis of no-on-transient A, a gene required for normal vision in Drosophila.
Neuron 1990;4(5):711-23.
1990: B E Kimmel; Ulrike Heberlein; Gerald M Rubin
The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype.
Genes & development 1990;4(5):712-27.
1990: M E Fortini; Gerald M Rubin
Analysis of cis-acting requirements of the Rh3 and Rh4 genes reveals a bipartite organization to rhodopsin promoters in Drosophila melanogaster.
Genes & development 1990;4(3):444-63.
1990: Marek Mlodzik; Y Hiromi; U Weber; Corey S Goodman; Gerald M Rubin
The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates.
Cell 1990;60(2):211-24.
1989: M A Simon; D D Bowtell; Gerald M Rubin
Structure and activity of the sevenless protein: a protein tyrosine kinase receptor required for photoreceptor development in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8333-7.
1989: F A Laski; S Ganguly; Phillip A Sharp; U L RajBhandary; Gerald M Rubin
Construction, stable transformation, and function of an amber suppressor tRNA gene in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(17):6696-8.
1989: Kevin Moses; M C Ellis; Gerald M Rubin
The glass gene encodes a zinc-finger protein required by Drosophila photoreceptor cells.
Nature 1989;340(6234):531-6.
1989: D D Bowtell; B E Kimmel; M A Simon; Gerald M Rubin
Regulation of the complex pattern of sevenless expression in the developing Drosophila eye.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(16):6245-9.
1989: Nicholas E Baker; Gerald M Rubin
Effect on eye development of dominant mutations in Drosophila homologue of the EGF receptor.
Nature 1989;340(6229):150-3.
1989: Gerald M Rubin
Development of the Drosophila retina: inductive events studied at single cell resolution.
Cell 1989;57(4):519-20.
1989: M C Mullins; Donald C Rio; Gerald M Rubin
cis-acting DNA sequence requirements for P-element transposition.
Genes & development 1989;3(5):729-38.
1989: F A Laski; Gerald M Rubin
Analysis of the cis-acting requirements for germ-line-specific splicing of the P-element ORF2-ORF3 intron.
Genes & development 1989;3(5):720-8.
1989: Craig Montell; Gerald M Rubin
Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction.
Neuron 1989;2(4):1313-23.
1989: D D Bowtell; M A Simon; Gerald M Rubin
Ommatidia in the developing Drosophila eye require and can respond to sevenless for only a restricted period.
Cell 1989;56(6):931-6.
1989: D Mismer; Gerald M Rubin
Definition of cis-acting elements regulating expression of the Drosophila melanogaster ninaE opsin gene by oligonucleotide-directed mutagenesis.
Genetics 1989;121(1):77-87.
1988: A Tomlinson; B E Kimmel; Gerald M Rubin
rough, a Drosophila homeobox gene required in photoreceptors R2 and R5 for inductive interactions in the developing eye.
Cell 1988;55(5):771-84.
1988: D Kalderon; Gerald M Rubin
Isolation and characterization of Drosophila cAMP-dependent protein kinase genes.
Genes & development 1988;2(12A):1539-56.
1988: D Mismer; majid shafaee; T R Laverty; Gerald M Rubin
Analysis of the promoter of the Rh2 opsin gene in Drosophila melanogaster.
Genetics 1988;120(1):173-80.
1988: Gerald M Rubin
Drosophila melanogaster as an experimental organism.
Science (New York, N.Y.) 1988;240(4858):1453-9.
1988: D D Bowtell; M A Simon; Gerald M Rubin
Nucleotide sequence and structure of the sevenless gene of Drosophila melanogaster.
Genes & development 1988;2(6):620-34.
1988: Charles S Zuker; D Mismer; R Hardy; Gerald M Rubin
Ectopic expression of a minor Drosophila opsin in the major photoreceptor cell class: distinguishing the role of primary receptor and cellular context.
Cell 1988;53(3):475-82.
1988: H Roiha; Gerald M Rubin; K O'Hare
P element insertions and rearrangements at the singed locus of Drosophila melanogaster.
Genetics 1988;119(1):75-83.
1988: Donald C Rio; G Barnes; F A Laski; Jasper Rine; Gerald M Rubin
Evidence for Drosophila P element transposase activity in mammalian cells and yeast.
Journal of molecular biology 1988;200(2):411-5.
1988: Craig Montell; Gerald M Rubin
The Drosophila ninaC locus encodes two photoreceptor cell specific proteins with domains homologous to protein kinases and the myosin heavy chain head.
Cell 1988;52(5):757-72.
1988: Steve Mount; M M Green; Gerald M Rubin
Partial revertants of the transposable element-associated suppressible allele white-apricot in Drosophila melanogaster: structures and responsiveness to genetic modifiers.
Genetics 1988;118(2):221-34.
1988: Gerald M Rubin
Sevenless, a gene encoding a putative receptor for positional information.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():417-24.
1987: A Tomlinson; D D Bowtell; Ernst Hafen; Gerald M Rubin
Localization of the sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila.
Cell 1987;51(1):143-50.
1986: F A Laski; Donald C Rio; Gerald M Rubin
Tissue specificity of Drosophila P element transposition is regulated at the level of mRNA splicing.
Cell 1986;44(1):7-19.
1986: Donald C Rio; F A Laski; Gerald M Rubin
Identification and immunochemical analysis of biologically active Drosophila P element transposase.
Cell 1986;44(1):21-32.
1985: R Levis; T Hazelrigg; Gerald M Rubin
Separable cis-acting control elements for expression of the white gene of Drosophila.
The EMBO journal 1985;4(13A):3489-99.
1985: R Levis; T Hazelrigg; Gerald M Rubin
Effects of genomic position on the expression of transduced copies of the white gene of Drosophila.
Science (New York, N.Y.) 1985;229(4713):558-61.
1985: Gerald M Rubin; T Hazelrigg; R E Karess; F A Laski; T Laverty; R Levis; Donald C Rio; F A Spencer; C S Zuker
Germ line specificity of P-element transposition and some novel patterns of expression of transduced copies of the white gene.
Cold Spring Harbor symposia on quantitative biology 1985;50():329-35.
1984: T Hazelrigg; R Levis; Gerald M Rubin
Transformation of white locus DNA in drosophila: dosage compensation, zeste interaction, and position effects.
Cell 1984;36(2):469-81.
1983: K O'hare; R Levis; Gerald M Rubin
Transcription of the white locus in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(22):6917-21.