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Abraham Rubinstein

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TOP 3
Meital Bloch; Yossi Kam; Dorit Moradov; Aviram Nissan; Ilana Ariel; Eylon Yavin; Abraham Rubinstein
The relative roles of charge and a recognition peptide in luminal targeting of colorectal cancer by fluorescent polyacrylamide.
Reem Smoum; Valery M Dembitsky; Abraham Rubinstein; Morris Srebnik
Boron containing compounds as protease inhibitors.
Elena Khazanov; Yvonne Kohl; Aviram Nissan; Amit Pascal; Meike Reimann-Zawadzki; Eylon Yavin; Abraham Rubinstein
Detecting a secreted gastric cancer biomarker molecule by targeted nanoparticles for real-time diagnostics.

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All Publications

2012: Meital Bloch; Yossi Kam; Dorit Moradov; Aviram Nissan; Ilana Ariel; Eylon Yavin; Abraham Rubinstein
The relative roles of charge and a recognition peptide in luminal targeting of colorectal cancer by fluorescent polyacrylamide.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;47(5):904-13.
2012: Reem Smoum; Valery M Dembitsky; Abraham Rubinstein; Morris Srebnik
Boron containing compounds as protease inhibitors.
Chemical reviews 2012;112(7):4156-220.
2012: Elena Khazanov; Yvonne Kohl; Aviram Nissan; Amit Pascal; Meike Reimann-Zawadzki; Eylon Yavin; Abraham Rubinstein
Detecting a secreted gastric cancer biomarker molecule by targeted nanoparticles for real-time diagnostics.
Pharmaceutical research 2012;29(4):983-93.
2012: Yossi Kam; Aviram Nissan; Abraham Rubinstein; David Halle; Eylon Yavin
Detection of endogenous K-ras mRNA in living cells at a single base resolution by a PNA molecular beacon.
Molecular pharmaceutics 2012;9(3):685-93.
2011: Mirela Nadler-Milbauer; Lior Apter; Yechezkel Barenholz; Sue Haupt; Ygal Haupt; Tamara Minko; Abraham Rubinstein
Synchronized release of Doxil and Nutlin-3 by remote degradation of polysaccharide matrices and its possible use in the local treatment of colorectal cancer.
Journal of drug targeting 2011;19(10):859-73.
2011: Efrat Harel; Elena Khazanov; Mirela Nadler Milbauer; Aviram Nissan; Abraham Rubinstein; Yechezkel Barenholz; Boaz Tirosh
Enhanced transferrin receptor expression by proinflammatory cytokines in enterocytes as a means for local delivery of drugs to inflamed gut mucosa.
PloS one 2011;6(9):e24202.
2010: Efrat Harel; Abraham Rubinstein; Weibin Chen; Eli Breuer; Boaz Tirosh
Aminoalkylcarbamoylphosphonates reduce TNFα release from activated immune cells.
Bioorganic & medicinal chemistry letters 2010;20(22):6518-23.
2010: Elena Khazanov; Noam Emmanuel; Abdel Kareem Azab; Yechezkel Barenholz; Eylon Yavin; Abraham Rubinstein
Specific detection of gastric alpha-antitrypsin by immobilized trypsin on polyHEMA films.
Molecular pharmaceutics 2010;7(4):944-52.
2009: Boaz Tirosh; Nadine Khatib; Yechezkel Barenholz; Aviram Nissan; Abraham Rubinstein
Transferrin as a luminal target for negatively charged liposomes in the inflamed colonic mucosa.
Molecular pharmaceutics 2009;6(4):1083-91.
2009: Dorit Moradov; Abed Al Aziz Al Quntar; Manar Youssef; Reem Smoum; Abraham Rubinstein; Morris Srebnik
Mo(CO)6-mediated intramolecular Pauson-Khand reaction of substituted diethyl 3-allyloxy-1-propynylphosphonates.
The Journal of organic chemistry 2009;74(3):1029-33.
2008: Abed Al Aziz Al Quntar; Alina Botvinik; Abraham Rubinstein; Morris Srebnik
Synthesis of 3-hydroxy-1-alkenylboronates via phosphine stabilized borylzirconacyclopropenes.
Chemical communications (Cambridge, England) 2008;(43):5589-91.
2008: Abdel Kareem Azab; Jackie Kleinstern; Morris Srebnik; Abraham Rubinstein
The metastatic stage-dependent mucosal expression of sialic acid is a potential marker for targeting colon cancer with cationic polymers.
Pharmaceutical research 2008;25(2):379-86.
2007: Abdel Kareem Azab; Jackie Kleinstern; Victoria Doviner; Boris Orkin; Morris Srebnik; Aviram Nissan; Abraham Rubinstein
Prevention of tumor recurrence and distant metastasis formation in a breast cancer mouse model by biodegradable implant of 131I-norcholesterol.
Journal of controlled release : official journal of the Controlled Release Society 2007;123(2):116-22.
2007: Abdel Kareem Azab; Victoria Doviner; Boris Orkin; Jackie Kleinstern; Morris Srebnik; Aviram Nissan; Abraham Rubinstein
Biocompatibility evaluation of crosslinked chitosan hydrogels after subcutaneous and intraperitoneal implantation in the rat.
Journal of biomedical materials research. Part A 2007;83(2):414-22.
2006: Susan Haupt; Jackie Kleinstern; Ygal Haupt; Abraham Rubinstein
Celecoxib can induce cell death independently of cyclooxygenase-2, p53, Mdm2, c-Abl and reactive oxygen species.
Anti-cancer drugs 2006;17(6):609-19.
2006: Reem Smoum; Abraham Rubinstein; Morris Srebnik
Chitosan-pentaglycine-phenylboronic acid conjugate: a potential colon-specific platform for calcitonin.
Bioconjugate chemistry 2006;17(4):1000-7.
2006: Susan Haupt; Tamar Zioni; Irith Gati; Jackie Kleinstern; Abraham Rubinstein
Luminal delivery and dosing considerations of local celecoxib administration to colorectal cancer.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;28(3):204-11.
2006: Abdel Kareem Azab; Boris Orkin; Victoria Doviner; Aviram Nissan; Martine Klein; Morris Srebnik; Abraham Rubinstein
Crosslinked chitosan implants as potential degradable devices for brachytherapy: in vitro and in vivo analysis.
Journal of controlled release : official journal of the Controlled Release Society 2006;111(3):281-9.
2006: Tareq Taha Jubeh; Mirela Nadler-Milbauer; Yechezkel Barenholz; Abraham Rubinstein
Local treatment of experimental colitis in the rat by negatively charged liposomes of catalase, TMN and SOD.
Journal of drug targeting 2006;14(3):155-63.
2005: Abdel Kareem Azab; Morris Srebnik; Victoria Doviner; Abraham Rubinstein
Targeting normal and neoplastic tissues in the rat jejunum and colon with boronated, cationic acrylamide copolymers.
Journal of controlled release : official journal of the Controlled Release Society 2005;106(1-2):14-25.
2005: Reem Smoum; Abraham Rubinstein; Morris Srebnik
Noncovalent inhibition of the serine proteases, alpha-chymotrypsin and trypsin by trifluoro(organo)borates.
Organic & biomolecular chemistry 2005;3(5):941-4.
2005: Tareq Taha Jubeh; Sivan Antler; Susan Haupt; Yechezkel Barenholz; Abraham Rubinstein
Local prevention of oxidative stress in the intestinal epithelium of the rat by adhesive liposomes of superoxide dismutase and tempamine.
Molecular pharmaceutics 2005;2(1):2-11.
2004: Tareq Taha Jubeh; Yechezkel Barenholz; Abraham Rubinstein
Differential adhesion of normal and inflamed rat colonic mucosa by charged liposomes.
Pharmaceutical research 2004;21(3):447-53.
2004: A David; Pavla Kopecková; Tamara Minko; Abraham Rubinstein; Jindrich Kopecek
Design of a multivalent galactoside ligand for selective targeting of HPMA copolymer-doxorubicin conjugates to human colon cancer cells.
European journal of cancer (Oxford, England : 1990) 2004;40(1):148-57.
2003: Reem Smoum; Abraham Rubinstein; Morris Srebnik
A study of the effect on nucleophilic hydrolytic activity of pancreatic elastase, trypsin, chymotrypsin, and leucine aminopeptidase by boronic acids in the presence of arabinogalactan: a subsequent study on the hydrolytic activity of chymotrypsin by boronic acids in the presence of mono-, di-, and trisaccharides.
Bioorganic chemistry 2003;31(6):464-74.
2002: Ayelet David; Pavla Kopecková; Jindrich Kopecek; Abraham Rubinstein
The role of galactose, lactose, and galactose valency in the biorecognition of N-(2-hydroxypropyl)methacrylamide copolymers by human colon adenocarcinoma cells.
Pharmaceutical research 2002;19(8):1114-22.
2002: Susan Haupt; Efrat Gil; Regin Tirosh; Ety Klinger; Alexander Gad; Abraham Rubinstein
Regional peptide uptake study in the rat intestinal mucosa: glatiramer acetate as a model drug.
Pharmaceutical research 2002;19(6):832-7.
2002: Susan Haupt; Abraham Rubinstein
The colon as a possible target for orally administered peptide and protein drugs.
Critical reviews in therapeutic drug carrier systems 2002;19(6):499-551.
2001: A David; Pavla Kopecková; Abraham Rubinstein; Jindrich Kopecek
Enhanced biorecognition and internalization of HPMA copolymers containing multiple or multivalent carbohydrate side-chains by human hepatocarcinoma cells.
Bioconjugate chemistry 2001;12(6):890-9.
2001: S Blau; N Levin; B Schwartz; Abraham Rubinstein
Adsorption of cationized bovine serum albumin onto epithelial crypt fractions of the rat colon.
Journal of pharmaceutical sciences 2001;90(10):1516-22.
2001: M Baluom; Michael Friedman; Abraham Rubinstein
Improved intestinal absorption of sulpiride in rats with synchronized oral delivery systems.
Journal of controlled release : official journal of the Controlled Release Society 2001;70(1-2):139-47.
2000: S Blau; R Kohen; P Bass; Abraham Rubinstein
The effect of local attachment of cationized antioxidant enzymes on experimental colitis in the rat.
Pharmaceutical research 2000;17(9):1077-84.
2000: M Baluom; Michael Friedman; P Assaf; Abdullah Haj-Yehia; Abraham Rubinstein
Synchronized release of sulpiride and sodium decanoate from HPMC matrices: a rational approach to enhance sulpiride absorption in the rat intestine.
Pharmaceutical research 2000;17(9):1071-6.
2000: S Blau; R Kohen; P Bass; Abraham Rubinstein
Relation between colonic inflammation severity and total low-molecular-weight antioxidant profiles in experimental colitis.
Digestive diseases and sciences 2000;45(6):1180-7.
2000: I Gliko-Kabir; Boris Yagen; M Baluom; Abraham Rubinstein
Phosphated crosslinked guar for colon-specific drug delivery. II. In vitro and in vivo evaluation in the rat.
Journal of controlled release : official journal of the Controlled Release Society 2000;63(1-2):129-34.
2000: I Gliko-Kabir; Boris Yagen; A Penhasi; Abraham Rubinstein
Phosphated crosslinked guar for colon-specific drug delivery. I. Preparation and physicochemical characterization.
Journal of controlled release : official journal of the Controlled Release Society 2000;63(1-2):121-7.
2000: S Blau; Tareq Taha Jubeh; Susan Haupt; Abraham Rubinstein
Drug targeting by surface cationization.
Critical reviews in therapeutic drug carrier systems 2000;17(5):425-65.
1999: S Blau; Abraham Rubinstein; P Bass; C Singaram; R Kohen
Differences in the reducing power along the rat GI tract: lower antioxidant capacity of the colon.
Molecular and cellular biochemistry 1999;194(1-2):185-91.
1998: I Gliko-Kabir; Boris Yagen; A Penhasi; Abraham Rubinstein
Low swelling, crosslinked guar and its potential use as colon-specific drug carrier.
Pharmaceutical research 1998;15(7):1019-25.
1998: B Tirosh; Abraham Rubinstein
Migration of adhesive and nonadhesive particles in the rat intestine under altered mucus secretion conditions.
Journal of pharmaceutical sciences 1998;87(4):453-6.
1997: Abraham Rubinstein; R Radai; M Friedman; P Fischer; Stefan Rokem
The effect of intestinal bacteria adherence on drug diffusion through solid films under stationary conditions.
Pharmaceutical research 1997;14(4):503-7.
1997: D A Adkin; CJ Kenyon; Elyakum Itzhak Lerner; I Landau; E Strauss; D Caron; A Penhasi; Abraham Rubinstein; Ian R Wilding
The use of scintigraphy to provide "proof of concept" for novel polysaccharide preparations designed for colonic drug delivery.
Pharmaceutical research 1997;14(1):103-7.
1994: Abraham Rubinstein; B Tirosh
Mucus gel thickness and turnover in the gastrointestinal tract of the rat: response to cholinergic stimulus and implication for mucoadhesion.
Pharmaceutical research 1994;11(6):794-9.
1993: Abraham Rubinstein; A Kakunda; Ron Kohen
Protection of the rat jejunal mucosa against oxidative injury by cationized superoxide dismutase.
Journal of pharmaceutical sciences 1993;82(12):1285-7.
1993: Ron Kohen; V Shadmi; A Kakunda; Abraham Rubinstein
Prevention of oxidative damage in the rat jejunal mucosa by pectin.
The British journal of nutrition 1993;69(3):789-800.
1993: Abraham Rubinstein; R Radai; M Ezra; S Pathak; Stefan Rokem
In vitro evaluation of calcium pectinate: a potential colon-specific drug delivery carrier.
Pharmaceutical research 1993;10(2):258-63.
1992: Ron Kohen; A Kakunda; Abraham Rubinstein
The role of cationized catalase and cationized glucose oxidase in mucosal oxidative damage induced in the rat jejunum.
The Journal of biological chemistry 1992;267(30):21349-54.
1992: Abraham Rubinstein; D Nakar; Amnon C Sintov
Colonic drug delivery: enhanced release of indomethacin from cross-linked chondroitin matrix in rat cecal content.
Pharmaceutical research 1992;9(2):276-8.
1992: Abraham Rubinstein; M Ezra; Stefan Rokem
Adhesion of bacteria on pectin casted films.
Microbios 1992;70(284-285):163-70.
1991: Abraham Rubinstein; Y V Pathak; J Kleinstern; A Reches; S Benita
In vitro release and intestinal absorption of physostigmine salicylate from submicron emulsions.
Journal of pharmaceutical sciences 1991;80(7):643-7.