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Brian Rudd

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TOP 3
Steven Boakes; Jesús Cortés; Antony appleyard; Brian A M Rudd; Michael J Dawson
Organization of the genes encoding the biosynthesis of actagardine and engineering of a variant generation system.
Antony appleyard; Shaila Choi; Daniel M Read; Ann Lightfoot; Steven Boakes; Anja Hoffmann; Ian Chopra; Gabriele Bierbaum; Brian A M Rudd; Michael J Dawson; Jesus Cortes
Dissecting structural and functional diversity of the lantibiotic mersacidin.
Russell Cox; Frank Glod; Deirdre Hurley; Colin M Lazarus; Thomas P Nicholson; Brian A M Rudd; Thomas J Simpson; Barrie Wilkinson; Ying Zhang
Rapid cloning and expression of a fungal polyketide synthase gene involved in squalestatin biosynthesis.

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All Publications

2009: Steven Boakes; Jesús Cortés; Antony appleyard; Brian A M Rudd; Michael J Dawson
Organization of the genes encoding the biosynthesis of actagardine and engineering of a variant generation system.
Molecular microbiology 2009;72(5):1126-36.
2009: Antony appleyard; Shaila Choi; Daniel M Read; Ann Lightfoot; Steven Boakes; Anja Hoffmann; Ian Chopra; Gabriele Bierbaum; Brian A M Rudd; Michael J Dawson; Jesus Cortes
Dissecting structural and functional diversity of the lantibiotic mersacidin.
Chemistry & biology 2009;16(5):490-8.
2004: Russell Cox; Frank Glod; Deirdre Hurley; Colin M Lazarus; Thomas P Nicholson; Brian A M Rudd; Thomas J Simpson; Barrie Wilkinson; Ying Zhang
Rapid cloning and expression of a fungal polyketide synthase gene involved in squalestatin biosynthesis.
Chemical communications (Cambridge, England) 2004;(20):2260-1.
2004: Steven Boakes; Markiyan Oliynyk; Jesús Cortés; Ines Böhm; Brian A M Rudd; W Peter Revill; James Staunton; Peter F Leadlay
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.
Journal of molecular microbiology and biotechnology 2004;8(2):73-80.
2003: Francesca Del Vecchio; Hrvoje Petkovic; Steven G Kendrew; Lindsey Low; Barrie Wilkinson; Rachel E Lill; Jesús Cortés; Brian A M Rudd; James Staunton; Peter F Leadlay
Active-site residue, domain and module swaps in modular polyketide synthases.
Journal of industrial microbiology & biotechnology 2003;30(8):489-94.
2002: Zohreh Hojati; Claire Milne; Barbara Harvey; Lyndsey Gordon; Matthew Borg; Fiona Flett; Barrie Wilkinson; Philip J Sidebottom; Brian A M Rudd; Martin A Hayes; Colin P Smith; Jason Micklefield
Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor.
Chemistry & biology 2002;9(11):1175-87.
2002: Jesús Cortés; Javier Velasco; Graham Foster; Andrew P Blackaby; Brian A M Rudd; Barrie Wilkinson
Identification and cloning of a type III polyketide synthase required for diffusible pigment biosynthesis in Saccharopolyspora erythraea.
Molecular microbiology 2002;44(5):1213-24.
2001: CJ Rowe; Ines Böhm; Iain Thomas; Barrie Wilkinson; Brian A M Rudd; Graham Foster; Andrew P Blackaby; Philip J Sidebottom; Y Roddis; AD Buss; James Staunton; Peter F Leadlay
Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase.
Chemistry & biology 2001;8(5):475-85.
2001: IE Holzbaur; A Ranganathan; Iain Thomas; D J Kearney; J A Reather; Brian A M Rudd; James Staunton; Peter F Leadlay
Molecular basis of Celmer's rules: role of the ketosynthase domain in epimerisation and demonstration that ketoreductase domains can have altered product specificity with unnatural substrates.
Chemistry & biology 2001;8(4):329-40.
2001: Thomas P Nicholson; Brian A M Rudd; M Dawson; Colin M Lazarus; Thomas J Simpson; Russell Cox
Design and utility of oligonucleotide gene probes for fungal polyketide synthases.
Chemistry & biology 2001;8(2):157-78.
2000: Barrie Wilkinson; Graham Foster; Brian A M Rudd; NL Taylor; Andrew P Blackaby; Philip J Sidebottom; D J Cooper; Michael J Dawson; AD Buss; Sabine Gaisser; Ines Böhm; CJ Rowe; Jesús Cortés; Peter F Leadlay; James Staunton
Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase.
Chemistry & biology 2000;7(2):111-7.
1999: C B Abel; John C Lindon; D Noble; Brian A M Rudd; Philip J Sidebottom; Jeremy K Nicholson
Characterization of metabolites in intact Streptomyces citricolor culture supernatants using high-resolution nuclear magnetic resonance and directly coupled high-pressure liquid chromatography-nuclear magnetic resonance spectroscopy.
Analytical biochemistry 1999;270(2):220-30.
1999: IE Holzbaur; R C Harris; Mark Bycroft; J Cortes; Christian P Bisang; James Staunton; Brian A M Rudd; Peter F Leadlay
Molecular basis of Celmer's rules: the role of two ketoreductase domains in the control of chirality by the erythromycin modular polyketide synthase.
Chemistry & biology 1999;6(4):189-95.
1998: O S Kinsman; P A Chalk; H C Jackson; RF Middleton; A Shuttleworth; Brian A M Rudd; C A Jones; H M Noble; H G Wildman; Michael J Dawson; C Stylli; Philip J Sidebottom; B Lamont; S Lynn; M V Hayes
Isolation and characterisation of an antifungal antibiotic (GR135402) with protein synthesis inhibition.
The Journal of antibiotics 1998;51(1):41-9.
1996: P Stead; Brian A M Rudd; H Bradshaw; D Noble; Michael J Dawson
Induction of phenazine biosynthesis in cultures of Pseudomonas aeruginosa by L-N-(3-oxohexanoyl)homoserine lactone.
FEMS microbiology letters 1996;140(1):15-22.
1992: C A Jones; Philip J Sidebottom; RJ Cannell; D Noble; Brian A M Rudd
The squalestatins, novel inhibitors of squalene synthase produced by a species of Phoma. III. Biosynthesis.
The Journal of antibiotics 1992;45(9):1492-8.