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Pauline Rudd

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Harvey David J; Merry Anthony H; Royle Louise; Campbell Matthew P; Dwek Raymond A; Rudd Pauline M
Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds.
Su Yunpeng; Royle Louise; Radcliffe Catherine M; Harvey David J; Dwek Raymond A; Martinez-Pomares Luisa; Rudd Pauline M
Detailed N-glycan analysis of mannose receptor purified from murine spleen indicates tissue specific sialylation.
Mackeen Mukram M; Almond Andrew; Deschamps Michael; Cumpstey Ian; Fairbanks Antony J; Tsang Clarence; Rudd Pauline M; Butters Terry D; Dwek Raymond A; Wormald Mark R
The conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway.

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All Publications

2009: Harvey David J; Merry Anthony H; Royle Louise; Campbell Matthew P; Dwek Raymond A; Rudd Pauline M
Proposal for a standard system for drawing structural diagrams of N- and O-linked carbohydrates and related compounds.
Proteomics 2009;9(15):3796-801.
2009: Su Yunpeng; Royle Louise; Radcliffe Catherine M; Harvey David J; Dwek Raymond A; Martinez-Pomares Luisa; Rudd Pauline M
Detailed N-glycan analysis of mannose receptor purified from murine spleen indicates tissue specific sialylation.
Biochemical and biophysical research communications 2009;384(4):436-43.
2009: Mackeen Mukram M; Almond Andrew; Deschamps Michael; Cumpstey Ian; Fairbanks Antony J; Tsang Clarence; Rudd Pauline M; Butters Terry D; Dwek Raymond A; Wormald Mark R
The conformational properties of the Glc3Man unit suggest conformational biasing within the chaperone-assisted glycoprotein folding pathway.
Journal of molecular biology 2009;387(2):335-47.
2009: Knezevic Ana; Polasek Ozren; Gornik Olga; Rudan Igor; Campbell Harry; Hayward Caroline; Wright Alan; Kolcic Ivana; O'Donoghue Niaobh; Bones Jonathan; Rudd Pauline M; Lauc Gordan
Variability, heritability and environmental determinants of human plasma N-glycome.
Journal of proteome research 2009;8(2):694-701.
2009: Jimenez-Dalmaroni Maximiliano J; Xiao Nengming; Corper Adam L; Verdino Petra; Ainge Gary D; Larsen Dave S; Painter Gavin F; Rudd Pauline M; Dwek Raymond A; Hoebe Kasper; Beutler Bruce; Wilson Ian A
Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.
PloS one 2009;4(10):e7411.
2008: Abd Hamid Umi M; Royle Louise; Saldova Radka; Radcliffe Catherine M; Harvey David J; Storr Sarah J; Pardo Maria; Antrobus Robin; Chapman Caroline J; Zitzmann Nicole; Robertson John F; Dwek Raymond A; Rudd Pauline M
A strategy to reveal potential glycan markers from serum glycoproteins associated with breast cancer progression.
Glycobiology 2008;18(12):1105-18.
2008: Royle Louise; Matthews Elizabeth; Corfield Anthony; Berry Monica; Rudd Pauline M; Dwek Raymond A; Carrington Stephen D
Glycan structures of ocular surface mucins in man, rabbit and dog display species differences.
Glycoconjugate journal 2008;25(8):763-73.
2008: Arnold James N; Saldova Radka; Hamid Umi M Abd; Rudd Pauline M
Evaluation of the serum N-linked glycome for the diagnosis of cancer and chronic inflammation.
Proteomics 2008;8(16):3284-93.
2008: Campbell Matthew P; Royle Louise; Radcliffe Catherine M; Dwek Raymond A; Rudd Pauline M
GlycoBase and autoGU: tools for HPLC-based glycan analysis.
Bioinformatics (Oxford, England) 2008;24(9):1214-6.
2008: Harvey David J; Royle Louise; Radcliffe Catherine M; Rudd Pauline M; Dwek Raymond A
Structural and quantitative analysis of N-linked glycans by matrix-assisted laser desorption ionization and negative ion nanospray mass spectrometry.
Analytical biochemistry 2008;376(1):44-60.
2008: Royle Louise; Campbell Matthew P; Radcliffe Catherine M; White Dawn M; Harvey David J; Abrahams Jodie L; Kim Yun-Gon; Henry George W; Shadick Nancy A; Weinblatt Michael E; Lee David M; Rudd Pauline M; Dwek Raymond A
HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software.
Analytical biochemistry 2008;376(1):1-12.
2008: Harvey David J; Crispin Max; Scanlan Chris; Singer Bernhard B; Lucka Lothar; Chang Veronica T; Radcliffe Catherine M; Thobhani Smita; Yuen Chun-Ting; Rudd Pauline M
Differentiation between isomeric triantennary N-linked glycans by negative ion tandem mass spectrometry and confirmation of glycans containing galactose attached to the bisecting (beta1-4-GlcNAc) residue in N-glycans from IgG.
Rapid communications in mass spectrometry : RCM 2008;22(7):1047-52.
2008: Miller Joanna L; deWet Barend J M; Martinez-Pomares Luisa; Radcliffe Catherine M; Dwek Raymond A; Rudd Pauline M; Gordon Siamon
The mannose receptor mediates dengue virus infection of macrophages.
PLoS pathogens 2008;4(2):e17.
2008: Peracaula Rosa; Barrabés Sílvia; Sarrats Ariadna; Rudd Pauline M; de Llorens Rafael
Altered glycosylation in tumours focused to cancer diagnosis.
Disease markers 2008;25(4-5):207-18.
2007: Saldova Radka; Royle Louise; Radcliffe Catherine M; Abd Hamid Umi M; Evans Rachel; Arnold James N; Banks Rosamonde E; Hutson Richard; Harvey David J; Antrobus Robin; Petrescu Stefana M; Dwek Raymond A; Rudd Pauline M
Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG.
Glycobiology 2007;17(12):1344-56.
2007: Scanlan Christopher N; Ritchie Gayle E; Baruah Kavitha; Crispin Max; Harvey David J; Singer Bernhard B; Lucka Lothar; Wormald Mark R; Wentworth Paul; Zitzmann Nicole; Rudd Pauline M; Burton Dennis R; Dwek Raymond A
Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody.
Journal of molecular biology 2007;372(1):16-22.
2007: Mimura Yusuke; Mimura-Kimura Yuka; Doores Katie; Golgher Denise; Davis Benjamin G; Dwek Raymond A; Rudd Pauline M; Elliott Tim
Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):5983-8.
2007: Barrabés Sílvia; Pagès-Pons Lluís; Radcliffe Catherine M; Tabarés Glòria; Fort Esther; Royle Louise; Harvey David J; Moenner Michel; Dwek Raymond A; Rudd Pauline M; De Llorens Rafael; Peracaula Rosa
Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer.
Glycobiology 2007;17(4):388-400.
2007: Radcliffe Catherine M; Arnold James N; Suter David M; Wormald Mark R; Harvey David J; Royle Louise; Mimura Yusuke; Kimura Yoshinobu; Sim Robert B; Inogès Susana; Rodriguez-Calvillo Mercedes; Zabalegui Natalia; de Cerio Ascensión López-Díaz; Potter Kathleen N; Mockridge C Ian; Dwek Raymond A; Bendandi Maurizio; Rudd Pauline M; Stevenson Freda K
Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor.
The Journal of biological chemistry 2007;282(10):7405-15.
2007: Robijn Marjolein L M; Koeleman Carolien A M; Wuhrer Manfred; Royle Louise; Geyer Rudolf; Dwek Raymond A; Rudd Pauline M; Deelder André M; Hokke Cornelis H
Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody.
Molecular and biochemical parasitology 2007;151(2):148-61.
2007: Arnold James N; Wormald Mark R; Sim Robert B; Rudd Pauline M; Dwek Raymond A
The impact of glycosylation on the biological function and structure of human immunoglobulins.
Annual review of immunology 2007;25():21-50.
2006: Fry Simon A; Van den Steen Philippe E; Royle Louise; Wormald Mark R; Leathem Anthony J; Opdenakker Ghislain; McDonnell James M; Dwek Raymond A; Rudd Pauline M
Cancer-associated glycoforms of gelatinase B exhibit a decreased level of binding to galectin-3.
Biochemistry 2006;45(51):15249-58.
2006: Oortwijn Beatrijs D; Roos Anja; Royle Louise; van Gijlswijk-Janssen Daniëlle J; Faber-Krol Maria C; Eijgenraam Jan-Willem; Dwek Raymond A; Daha Mohamed R; Rudd Pauline M; van Kooten Cees
Differential glycosylation of polymeric and monomeric IgA: a possible role in glomerular inflammation in IgA nephropathy.
Journal of the American Society of Nephrology : JASN 2006;17(12):3529-39.
2006: Omtvedt Lone A; Royle Louise; Husby Gunnar; Sletten Knut; Radcliffe Catherine M; Harvey David J; Dwek Raymond A; Rudd Pauline M
Glycan analysis of monoclonal antibodies secreted in deposition disorders indicates that subsets of plasma cells differentially process IgG glycans.
Arthritis and rheumatism 2006;54(11):3433-40.
2006: Tsiftsoglou Stefanos A; Arnold James N; Roversi Pietro; Crispin Max D; Radcliffe Catherine; Lea Susan M; Dwek Raymond A; Rudd Pauline M; Sim Robert B
Human complement factor I glycosylation: structural and functional characterisation of the N-linked oligosaccharides.
Biochimica et biophysica acta 2006;1764(11):1757-66.
2006: Jayachandran Rajesh; Radcliffe Catherine M; Royle Louise; Harvey David J; Dwek Raymond A; Rudd Pauline M; Karande Anjali A
Oligosaccharides modulate the apoptotic activity of glycodelin.
Glycobiology 2006;16(11):1052-63.
2006: Arnold James N; Dwek Raymond A; Rudd Pauline M; Sim Robert B
Mannan binding lectin and its interaction with immunoglobulins in health and in disease.
Immunology letters 2006;106(2):103-10.
2006: Crispin Max; Harvey David J; Chang Veronica T; Yu Chao; Aricescu A Radu; Jones E Yvonne; Davis Simon J; Dwek Raymond A; Rudd Pauline M
Inhibition of hybrid- and complex-type glycosylation reveals the presence of the GlcNAc transferase I-independent fucosylation pathway.
Glycobiology 2006;16(8):748-56.
2006: Webber Dawn; Radcliffe Catherine M; Royle Louise; Tobiasen Gemma; Merry Anthony H; Rodgers Allen L; Sturrock Edward D; Wormald Mark R; Harvey David J; Dwek Raymond A; Rudd Pauline M
Sialylation of urinary prothrombin fragment 1 is implicated as a contributory factor in the risk of calcium oxalate kidney stone formation.
The FEBS journal 2006;273(13):3024-37.
2006: Van den Steen Philippe E; Van Aelst Ilse; Hvidberg Vibeke; Piccard Helene; Fiten Pierre; Jacobsen Christian; Moestrup Soren K; Fry Simon; Royle Louise; Wormald Mark R; Wallis Russell; Rudd Pauline M; Dwek Raymond A; Opdenakker Ghislain
The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors.
The Journal of biological chemistry 2006;281(27):18626-37.
2006: Jacquemin M; Radcliffe C M; Lavend'homme R; Wormald M R; Vanderelst L; Wallays G; Dewaele J; Collen D; Vermylen J; Dwek R A; Saint-Remy J-M; Rudd P M; Dewerchin M
Variable region heavy chain glycosylation determines the anticoagulant activity of a factor VIII antibody.
Journal of thrombosis and haemostasis : JTH 2006;4(5):1047-55.
2006: Shore D A; Teyton L; Dwek R A; Rudd P M; Wilson I A
Crystal structure of the TCR co-receptor CD8alphaalpha in complex with monoclonal antibody YTS 105.18 Fab fragment at 2.88 A resolution.
Journal of molecular biology 2006;358(2):347-54.
2006: Opdenakker Ghislain; Dillen Chris; Fiten Pierre; Martens Erik; Van Aelst Ilse; Van den Steen Philippe E; Nelissen Inge; Starckx Sofie; Descamps Francis J; Hu Jialiang; Piccard Helene; Van Damme Jo; Wormald Mark R; Rudd Pauline M; Dwek Raymond A
Remnant epitopes, autoimmunity and glycosylation.
Biochimica et biophysica acta 2006;1760(4):610-5.
2006: Harvey David J; Dwek Raymond A; Rudd Pauline M
Determining the structure of glycan moieties by mass spectrometry.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2006;Chapter 12():Unit 12.7.
2006: Royle Louise; Dwek Raymond A; Rudd Pauline M
Determining the structure of oligosaccharides N- and O-linked to glycoproteins.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2006;Chapter 12():Unit 12.6.
2006: Arnold James N; Wallis Russell; Willis Antony C; Harvey David J; Royle Louise; Dwek Raymond A; Rudd Pauline M; Sim Robert B
Interaction of mannan binding lectin with alpha2 macroglobulin via exposed oligomannose glycans: a conserved feature of the thiol ester protein family?
The Journal of biological chemistry 2006;281(11):6955-63.
2006: Tabarés Glòria; Radcliffe Catherine M; Barrabés Sílvia; Ramírez Manel; Aleixandre R Núria; Hoesel Wolfgang; Dwek Raymond A; Rudd Pauline M; Peracaula Rosa; de Llorens Rafael
Different glycan structures in prostate-specific antigen from prostate cancer sera in relation to seminal plasma PSA.
Glycobiology 2006;16(2):132-45.
2006: Royle Louise; Radcliffe Catherine M; Dwek Raymond A; Rudd Pauline M
Detailed structural analysis of N-glycans released from glycoproteins in SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions.
Methods in molecular biology (Clifton, N.J.) 2006;347():125-43.
2005: Su Yunpeng; Bakker Talitha; Harris James; Tsang Clarence; Brown Gordon D; Wormald Mark R; Gordon Siamon; Dwek Raymond A; Rudd Pauline M; Martinez-Pomares Luisa
Glycosylation influences the lectin activities of the macrophage mannose receptor.
The Journal of biological chemistry 2005;280(38):32811-20.
2005: Arnold James N; Wormald Mark R; Suter David M; Radcliffe Catherine M; Harvey David J; Dwek Raymond A; Rudd Pauline M; Sim Robert B
Human serum IgM glycosylation: identification of glycoforms that can bind to mannan-binding lectin.
The Journal of biological chemistry 2005;280(32):29080-7.
2005: Jerkovic Lidija; Voegele Andreas F; Chwatal Sabine; Kronenberg Florian; Radcliffe Catherine M; Wormald Mark R; Lobentanz Eva M; Ezeh Benjie; Eller Patricia; Dejori Norbert; Dieplinger Benjamin; Lottspeich Friedrich; Sattler Wolfgang; Uhr Manfred; Mechtler Karl; Dwek Raymond A; Rudd Pauline M; Baier Gottfried; Dieplinger Hans
Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression.
Journal of proteome research 2005;4(3):889-99.
2005: Jorgensen-Tye B; Levesque J-P; Royle L; Doyonnas R; Chan J Y-H; Dwek R A; Rudd P M; Harvey D J; Simmons P J; Watt S M
Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis.
Tissue antigens 2005;65(3):220-39.
2005: Zajonc Dirk M; Crispin M D Max; Bowden Thomas A; Young David C; Cheng Tan-Yun; Hu Jingdan; Costello Catherine E; Rudd Pauline M; Dwek Raymond A; Miller Marvin J; Brenner Michael B; Moody D Branch; Wilson Ian A
Molecular mechanism of lipopeptide presentation by CD1a.
Immunity 2005;22(2):209-19.
2005: Fry Simon A; Van den Steen Philippe E; Royle Louise; Wormald Mark R; Leathem Anthony J; Opdenakker Ghislain; Rudd Pauline M; Dwek Raymond A
Differential glycosylation of gelatinase B from neutrophils and breast cancer cells.
Advances in experimental medicine and biology 2005;564():103-12.
2005: Mimura Yusuke; Golgher Denise; Mimura-Kimura Yuka; Dwek Raymond A; Rudd Pauline M; Elliott Tim
Immunogenicity of calreticulin-bound murine leukemia virus glycoprotein gp90.
Advances in experimental medicine and biology 2005;564():85-94.
2005: Shore David A; Wilson Ian A; Dwek Raymond A; Rudd Pauline M
Glycosylation and the function of the T cell co-receptor CD8.
Advances in experimental medicine and biology 2005;564():71-84.
2005: Arnold James N; Royle Louise; Dwek Raymond A; Rudd Pauline M; Sim Robert B
Human immunoglobulin glycosylation and the lectin pathway of complement activation.
Advances in experimental medicine and biology 2005;564():27-43.
2005: Su Yunpeng Roc; Tsang Clarence; Bakker Talitha; Harris James; Gordon Siamon; Dwek Raymond A; Martinez-Pomares Luisa; Rudd Pauline M
Glycosylation influences the ligand binding activities of mannose receptor.
Advances in experimental medicine and biology 2005;564():25-6.
2004: Arnold James N; Radcliffe Catherine M; Wormald Mark R; Royle Louise; Harvey David J; Crispin Max; Dwek Raymond A; Sim Robert B; Rudd Pauline M
The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):6831-40.
2004: O'Leary Joanne M; Radcliffe Catherine M; Willis Antony C; Dwek Raymond A; Rudd Pauline M; Downing A Kristina
Identification and removal of O-linked and non-covalently linked sugars from recombinant protein produced using Pichia pastoris.
Protein expression and purification 2004;38(2):217-27.
2004: Rudd Pauline M; Wormald Mark R; Dwek Raymond A
Sugar-mediated ligand-receptor interactions in the immune system.
Trends in biotechnology 2004;22(10):524-30.
2004: Tekoah Yoram; Ko Kisung; Koprowski Hilary; Harvey David J; Wormald Mark R; Dwek Raymond A; Rudd Pauline M
Controlled glycosylation of therapeutic antibodies in plants.
Archives of biochemistry and biophysics 2004;426(2):266-78.
2004: Crispin M D Max; Ritchie Gayle E; Critchley Alison J; Morgan B Paul; Wilson Ian A; Dwek Raymond A; Sim Robert B; Rudd Pauline M
Monoglucosylated glycans in the secreted human complement component C3: implications for protein biosynthesis and structure.
FEBS letters 2004;566(1-3):270-4.
2004: Lee Hing-Ken; Scanlan Christopher N; Huang Cheng-Yuan; Chang Aileen Y; Calarese Daniel A; Dwek Raymond A; Rudd Pauline M; Burton Dennis R; Wilson Ian A; Wong Chi-Huey
Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody.
Angewandte Chemie (International ed. in English) 2004;43(8):1000-3.
2004: Lukacik P; Roversi P; White J; Esser D; Smith G P; Billington J; Williams P A; Rudd P M; Wormald M R; Harvey D J; Crispin M D M; Radcliffe C M; Dwek R A; Evans D J; Morgan B P; Smith R A G; Lea S M
Complement regulation at the molecular level: the structure of decay-accelerating factor.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1279-84.
2004: Omtvedt L A; Royle L; Husby G; Sletten K; Radcliffe C; Dwek R A; Rudd P M; Harvey D J
Artefacts formed by addition of urea to N-linked glycans released with peptide-N-glycosidase F for analysis by mass spectrometry.
Rapid communications in mass spectrometry : RCM 2004;18(19):2357-9.
2003: Butler Michael; Quelhas D; Critchley Alison J; Carchon Hubert; Hebestreit Holger F; Hibbert Richard G; Vilarinho Laura; Teles E; Matthijs Gert; Schollen Els; Argibay Pablo; Harvey David J; Dwek Raymond A; Jaeken Jaak; Rudd Pauline M
Detailed glycan analysis of serum glycoproteins of patients with congenital disorders of glycosylation indicates the specific defective glycan processing step and provides an insight into pathogenesis.
Glycobiology 2003;13(9):601-22.
2003: Merry Anthony H; Gilbert Robert J C; Shore David A; Royle Louise; Miroshnychenko Olga; Vuong Mai; Wormald Mark R; Harvey David J; Dwek Raymond A; Classon Brendan J; Rudd Pauline M; Davis Simon J
O-glycan sialylation and the structure of the stalk-like region of the T cell co-receptor CD8.
The Journal of biological chemistry 2003;278(29):27119-28.
2003: Calarese Daniel A; Scanlan Christopher N; Zwick Michael B; Deechongkit Songpon; Mimura Yusuke; Kunert Renate; Zhu Ping; Wormald Mark R; Stanfield Robyn L; Roux Kenneth H; Kelly Jeffery W; Rudd Pauline M; Dwek Raymond A; Katinger Hermann; Burton Dennis R; Wilson Ian A
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition.
Science (New York, N.Y.) 2003;300(5628):2065-71.
2003: Ko Kisung; Tekoah Yoram; Rudd Pauline M; Harvey David J; Dwek Raymond A; Spitsin Sergei; Hanlon Cathleen A; Rupprecht Charles; Dietzschold Bernhard; Golovkin Maxim; Koprowski Hilary
Function and glycosylation of plant-derived antiviral monoclonal antibody.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):8013-8.
2003: Peracaula Rosa; Tabarés Glòria; Royle Louise; Harvey David J; Dwek Raymond A; Rudd Pauline M; de Llorens Rafael
Altered glycosylation pattern allows the distinction between prostate-specific antigen (PSA) from normal and tumor origins.
Glycobiology 2003;13(6):457-70.
2003: Royle Louise; Roos Anja; Harvey David J; Wormald Mark R; van Gijlswijk-Janssen Daniëlle; Redwan El-Rashdy M; Wilson Ian A; Daha Mohamed R; Dwek Raymond A; Rudd Pauline M
Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems.
The Journal of biological chemistry 2003;278(22):20140-53.
2003: Peracaula Rosa; Royle Louise; Tabares Glòria; Mallorqui-Fernández Goretti; Barrabés Silvia; Harvey David J; Dwek Raymond A; Rudd Pauline M; de Llorens Rafael
Glycosylation of human pancreatic ribonuclease: differences between normal and tumor states.
Glycobiology 2003;13(4):227-44.
2003: Scanlan Christopher N; Pantophlet Ralph; Wormald Mark R; Saphire Erica Ollmann; Calarese Daniel; Stanfield Robyn; Wilson Ian A; Katinger Hermann; Dwek Raymond A; Burton Dennis R; Rudd Pauline M
The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12.
Advances in experimental medicine and biology 2003;535():205-18.
2003: Saphire Erica Ollmann; Stanfield Robyn L; Crispin M D Max; Morris Garrett; Zwick Michael B; Pantophlet Ralph A; Parren Paul W H I; Rudd Pauline M; Dwek Raymond A; Burton Dennis R; Wilson Ian A
Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design.
Advances in experimental medicine and biology 2003;535():55-66.
2002: Van den Steen Philippe E; Dubois Bénédicte; Nelissen Inge; Rudd Pauline M; Dwek Raymond A; Opdenakker Ghislain
Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9).
Critical reviews in biochemistry and molecular biology 2002;37(6):375-536.
2002: Navazio Lorella; Miuzzo Manuela; Royle Louise; Baldan Barbara; Varotto Serena; Merry Anthony H; Harvey David J; Dwek Raymond A; Rudd Pauline M; Mariani Paola
Monitoring endoplasmic reticulum-to-Golgi traffic of a plant calreticulin by protein glycosylation analysis.
Biochemistry 2002;41(48):14141-9.
2002: Radcliffe Catherine M; Diedrich Gundo; Harvey David J; Dwek Raymond A; Cresswell Peter; Rudd Pauline M
Identification of specific glycoforms of major histocompatibility complex class I heavy chains suggests that class I peptide loading is an adaptation of the quality control pathway involving calreticulin and ERp57.
The Journal of biological chemistry 2002;277(48):46415-23.
2002: Rudd Pauline M; Merry Anthony H; Wormald Mark R; Dwek Raymond A
Glycosylation and prion protein.
Current opinion in structural biology 2002;12(5):578-86.
2002: Scanlan Christopher N; Pantophlet Ralph; Wormald Mark R; Ollmann Saphire Erica; Stanfield Robyn; Wilson Ian A; Katinger Hermann; Dwek Raymond A; Rudd Pauline M; Burton Dennis R
The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.
Journal of virology 2002;76(14):7306-21.
2002: Saphire Erica Ollmann; Stanfield Robyn L; Crispin M D Max; Parren Paul W H I; Rudd Pauline M; Dwek Raymond A; Burton Dennis R; Wilson Ian A
Contrasting IgG structures reveal extreme asymmetry and flexibility.
Journal of molecular biology 2002;319(1):9-18.
2002: Merry Anthony H; Neville David C A; Royle Louise; Matthews Brian; Harvey David J; Dwek Raymond A; Rudd Pauline M
Recovery of intact 2-aminobenzamide-labeled O-glycans released from glycoproteins by hydrazinolysis.
Analytical biochemistry 2002;304(1):91-9.
2002: Royle Louise; Mattu Taj S; Hart Edmund; Langridge James I; Merry Anthony H; Murphy Neil; Harvey David J; Dwek Raymond A; Rudd Pauline M
An analytical and structural database provides a strategy for sequencing O-glycans from microgram quantities of glycoproteins.
Analytical biochemistry 2002;304(1):70-90.
2002: Wheeler Susan F; Rudd Pauline M; Davis Simon J; Dwek Raymond A; Harvey David J
Comparison of the N-linked glycans from soluble and GPI-anchored CD59 expressed in CHO cells.
Glycobiology 2002;12(4):261-71.
2002: Magnadóttir Bergljót; Crispin Max; Royle Louise; Colominas Cristina; Harvey David J; Dwek Raymond A; Rudd Pauline M
The carbohydrate moiety of serum IgM from Atlantic cod (Gadus morhua L.).
Fish & shellfish immunology 2002;12(3):209-27.
2002: Harvey David J; Mattu Taj S; Wormald Mark R; Royle Louise; Dwek Raymond A; Rudd Pauline M
"Internal residue loss": rearrangements occurring during the fragmentation of carbohydrates derivatized at the reducing terminus.
Analytical chemistry 2002;74(4):734-40.
2002: Ritchie Gayle E; Moffatt Beryl E; Sim Robert B; Morgan B Paul; Dwek Raymond A; Rudd Pauline M
Glycosylation and the complement system.
Chemical reviews 2002;102(2):305-20-19.
2001: Garner B; Harvey D J; Royle L; Frischmann M; Nigon F; Chapman M J; Rudd P M
Characterization of human apolipoprotein B100 oligosaccharides in LDL subfractions derived from normal and hyperlipidemic plasma: deficiency of alpha-N-acetylneuraminyllactosyl-ceramide in light and small dense LDL particles.
Glycobiology 2001;11(10):791-802.
2001: Saphire E O; Parren P W; Pantophlet R; Zwick M B; Morris G M; Rudd P M; Dwek R A; Stanfield R L; Burton D R; Wilson I A
Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.
Science (New York, N.Y.) 2001;293(5532):1155-9.
2001: Garner B; Merry A H; Royle L; Harvey D J; Rudd P M; Thillet J
Structural elucidation of the N- and O-glycans of human apolipoprotein(a): role of o-glycans in conferring protease resistance.
The Journal of biological chemistry 2001;276(25):22200-8.
2001: Rudd P M; Wormald M R; Wing D R; Prusiner S B; Dwek R A
Prion glycoprotein: structure, dynamics, and roles for the sugars.
Biochemistry 2001;40(13):3759-66.
2001: Rudd P M; Elliott T; Cresswell P; Wilson I A; Dwek R A
Glycosylation and the immune system.
Science (New York, N.Y.) 2001;291(5512):2370-6.
2001: Rudd P M; Colominas C; Royle L; Murphy N; Hart E; Merry A H; Hebestreit H F; Dwek R A
A high-performance liquid chromatography based strategy for rapid, sensitive sequencing of N-linked oligosaccharide modifications to proteins in sodium dodecyl sulphate polyacrylamide electrophoresis gel bands.
Proteomics 2001;1(2):285-94.
2000: Mattu T S; Royle L; Langridge J; Wormald M R; Van den Steen P E; Van Damme J; Opdenakker G; Harvey D J; Dwek R A; Rudd P M
O-glycan analysis of natural human neutrophil gelatinase B using a combination of normal phase-HPLC and online tandem mass spectrometry: implications for the domain organization of the enzyme.
Biochemistry 2000;39(51):15695-704.
2000: Rudd P M; Downing A K; Cadene M; Harvey D J; Wormald M R; Weir I; Dwek R A; Rifkin D B; Gleizes P E
Hybrid and complex glycans are linked to the conserved N-glycosylation site of the third eight-cysteine domain of LTBP-1 in insect cells.
Biochemistry 2000;39(7):1596-603.
1999: Devasahayam M; Catalino P D; Rudd P M; Dwek R A; Barclay A N
The glycan processing and site occupancy of recombinant Thy-1 is markedly affected by the presence of a glycosylphosphatidylinositol anchor.
Glycobiology 1999;9(12):1381-7.
1999: Rudd P M; Endo T; Colominas C; Groth D; Wheeler S F; Harvey D J; Wormald M R; Serban H; Prusiner S B; Kobata A; Dwek R A
Glycosylation differences between the normal and pathogenic prion protein isoforms.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(23):13044-9.
1999: Rudd P M; Wormald M R; Stanfield R L; Huang M; Mattsson N; Speir J A; DiGennaro J A; Fetrow J S; Dwek R A; Wilson I A
Roles for glycosylation of cell surface receptors involved in cellular immune recognition.
Journal of molecular biology 1999;293(2):351-66.
1999: Rudd P M; Mattu T S; Masure S; Bratt T; Van den Steen P E; Wormald M R; Küster B; Harvey D J; Borregaard N; Van Damme J; Dwek R A; Opdenakker G
Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.
Biochemistry 1999;38(42):13937-50.
1999: Rudd P M; Wormald M R; Harvey D J; Devasahayam M; McAlister M S; Brown M H; Davis S J; Barclay A N; Dwek R A
Oligosaccharide analysis and molecular modeling of soluble forms of glycoproteins belonging to the Ly-6, scavenger receptor, and immunoglobulin superfamilies expressed in Chinese hamster ovary cells.
Glycobiology 1999;9(5):443-58.
1999: Rudd P M; Mattu T S; Zitzmann N; Mehta A; Colominas C; Hart E; Opdenakker G; Dwek R A
Glycoproteins: rapid sequencing technology for N-linked and GPI anchor glycans.
Biotechnology & genetic engineering reviews 1999;16():1-21.
1998: Van den Steen P; Rudd P M; Proost P; Martens E; Paemen L; Küster B; van Damme J; Dwek R A; Opdenakker G
Oligosaccharides of recombinant mouse gelatinase B variants.
Biochimica et biophysica acta 1998;1425(3):587-98.
1998: McAlister M S; Brown M H; Willis A C; Rudd P M; Harvey D J; Aplin R; Shotton D M; Dwek R A; Barclay A N; Driscoll P C
Structural analysis of the CD5 antigen--expression, disulphide bond analysis and physical characterisation of CD5 scavenger receptor superfamily domain 1.
European journal of biochemistry / FEBS 1998;257(1):131-41.
1998: Rudd P M; Wormald M R; Dwek R A
Glycosylation and the immune system.
Journal of protein chemistry 1998;17(6):519.
1998: Mehta A; Zitzmann N; Rudd P M; Block T M; Dwek R A
Alpha-glucosidase inhibitors as potential broad based anti-viral agents.
FEBS letters 1998;430(1-2):17-22.
1998: Mattu T S; Pleass R J; Willis A C; Kilian M; Wormald M R; Lellouch A C; Rudd P M; Woof J M; Dwek R A
The glycosylation and structure of human serum IgA1, Fab, and Fc regions and the role of N-glycosylation on Fc alpha receptor interactions.
The Journal of biological chemistry 1998;273(4):2260-72.
1998: Van den Steen P; Rudd P M; Dwek R A; Opdenakker G
Concepts and principles of O-linked glycosylation.
Critical reviews in biochemistry and molecular biology 1998;33(3):151-208.
1998: Rudd P M; Morgan B P; Wormald M R; Harvey D J; van den Berg C W; Davis S J; Ferguson M A; Dwek R A
The glycosylation of the complement regulatory protein, human erythrocyte CD59.
Advances in experimental medicine and biology 1998;435():153-62.
1998: Van den Steen P; Rudd P M; Dwek R A; Van Damme J; Opdenakker G
Cytokine and protease glycosylation as a regulatory mechanism in inflammation and autoimmunity.
Advances in experimental medicine and biology 1998;435():133-43.
1997: Mehta A; Rudd P M; Block T M; Dwek R A
A strategy for anti-viral intervention: the use of alpha-glucosidase inhibitors to prevent chaperone-mediated folding of viral envelope glycoproteins.
Biochemical Society transactions 1997;25(4):1188-93.
1997: Rudd P M; Morgan B P; Wormald M R; Harvey D J; van den Berg C W; Davis S J; Ferguson M A; Dwek R A
Roles for glycosylation in the anti-inflammatory molecule CD59.
Biochemical Society transactions 1997;25(4):1177-84.
1997: Rudd P M; Dwek R A
Rapid, sensitive sequencing of oligosaccharides from glycoproteins.
Current opinion in biotechnology 1997;8(4):488-97.
1997: Rudd P M; Guile G R; Küster B; Harvey D J; Opdenakker G; Dwek R A
Oligosaccharide sequencing technology.
Nature 1997;388(6638):205-7.
1997: Rudd P M; Morgan B P; Wormald M R; Harvey D J; van den Berg C W; Davis S J; Ferguson M A; Dwek R A
The glycosylation of the complement regulatory protein, human erythrocyte CD59.
The Journal of biological chemistry 1997;272(11):7229-44.
1997: Wormald M R; Rudd P M; Harvey D J; Chang S C; Scragg I G; Dwek R A
Variations in oligosaccharide-protein interactions in immunoglobulin G determine the site-specific glycosylation profiles and modulate the dynamic motion of the Fc oligosaccharides.
Biochemistry 1997;36(6):1370-80.
1997: Rudd P M; Dwek R A
Glycosylation: heterogeneity and the 3D structure of proteins.
Critical reviews in biochemistry and molecular biology 1997;32(1):1-100.
1996: Iourin O; Mattu T S; Mian N; Keir G; Winchester B; Dwek R A; Rudd P M
The identification of abnormal glycoforms of serum transferrin in carbohydrate deficient glycoprotein syndrome type I by capillary zone electrophoresis.
Glycoconjugate journal 1996;13(6):1031-42.
1996: Guile G R; Rudd P M; Wing D R; Prime S B; Dwek R A
A rapid high-resolution high-performance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles.
Analytical biochemistry 1996;240(2):210-26.
1995: Rudd P M; Woods R J; Wormald M R; Opdenakker G; Downing A K; Campbell I D; Dwek R A
The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator.
Biochimica et biophysica acta 1995;1248(1):1-10.
1995: Opdenakker G; Rudd P M; Wormald M; Dwek R A; Van Damme J
Cells regulate the activities of cytokines by glycosylation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(5):453-7.
1995: Malhotra R; Wormald M R; Rudd P M; Fischer P B; Dwek R A; Sim R B
Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein.
Nature medicine 1995;1(3):237-43.
1995: Mori K; Dwek R A; Downing A K; Opdenakker G; Rudd P M
The activation of type 1 and type 2 plasminogen by type I and type II tissue plasminogen activator.
The Journal of biological chemistry 1995;270(7):3261-7.
1994: Rudd P M; Fortune F; Patel T; Parekh R B; Dwek R A; Lehner T
A human T-cell receptor recognizes 'O'-linked sugars from the hinge region of human IgA1 and IgD.
Immunology 1994;83(1):99-106.
1994: Field M C; Amatayakul-Chantler S; Rademacher T W; Rudd P M; Dwek R A
Structural analysis of the N-glycans from human immunoglobulin A1: comparison of normal human serum immunoglobulin A1 with that isolated from patients with rheumatoid arthritis.
The Biochemical journal 1994;299 ( Pt 1)():261-75.
1994: Rudd P M; Joao H C; Coghill E; Fiten P; Saunders M R; Opdenakker G; Dwek R A
Glycoforms modify the dynamic stability and functional activity of an enzyme.
Biochemistry 1994;33(1):17-22.
1993: Opdenakker G; Rudd P M; Ponting C P; Dwek R A
Concepts and principles of glycobiology.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(14):1330-7.
1992: Rudd P M; Scragg I G; Coghill E; Dwek R A
Separation and analysis of the glycoform populations of ribonuclease B using capillary electrophoresis.
Glycoconjugate journal 1992;9(2):86-91.
1991: Rudd P M; Leatherbarrow R J; Rademacher T W; Dwek R A
Diversification of the IgG molecule by oligosaccharides.
Molecular immunology 1991;28(12):1369-78.
1989: Parekh R B; Dwek R A; Rudd P M; Thomas J R; Rademacher T W; Warren T; Wun T C; Hebert B; Reitz B; Palmier M
N-glycosylation and in vitro enzymatic activity of human recombinant tissue plasminogen activator expressed in Chinese hamster ovary cells and a murine cell line.
Biochemistry 1989;28(19):7670-9.
1989: Wittwer A J; Howard S C; Carr L S; Harakas N K; Feder J; Parekh R B; Rudd P M; Dwek R A; Rademacher T W
Effects of N-glycosylation on in vitro activity of Bowes melanoma and human colon fibroblast derived tissue plasminogen activator.
Biochemistry 1989;28(19):7662-9.

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