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Frank Ruddle

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Enkhmandakh Badam; Makeyev Aleksandr V; Erdenechimeg Lkhamsuren; Ruddle Frank H; Chimge Nyam-Osor; Tussie-Luna Maria Isabel; Roy Ananda L; Bayarsaihan Dashzeveg
Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development.
Chimge Nyam-Osor; Makeyev Aleksandr V; Ruddle Frank H; Bayarsaihan Dashzeveg
Identification of the TFII-I family target genes in the vertebrate genome.
Chimge Nyam-Osor; Mungunsukh Ognoon; Ruddle Frank; Bayarsaihan Dashzeveg
Gene expression analysis of TFII-I modulated genes in mouse embryonic fibroblasts.

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All Publications

2009: Enkhmandakh Badam; Makeyev Aleksandr V; Erdenechimeg Lkhamsuren; Ruddle Frank H; Chimge Nyam-Osor; Tussie-Luna Maria Isabel; Roy Ananda L; Bayarsaihan Dashzeveg
Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):181-6.
2008: Chimge Nyam-Osor; Makeyev Aleksandr V; Ruddle Frank H; Bayarsaihan Dashzeveg
Identification of the TFII-I family target genes in the vertebrate genome.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(26):9006-10.
2007: Chimge Nyam-Osor; Mungunsukh Ognoon; Ruddle Frank; Bayarsaihan Dashzeveg
Gene expression analysis of TFII-I modulated genes in mouse embryonic fibroblasts.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2007;308(3):225-35.
2007: Chimge Nyam-Osor; Mungunsukh Ognoon; Ruddle Frank; Bayarsaihan Dashzeveg
Expression profiling of BEN regulated genes in mouse embryonic fibroblasts.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2007;308(3):209-24.
2007: Liao Shan; Bentley Kevin; Lebrun Marielle; Lesslauer Werner; Ruddle Frank H; Ruddle Nancy H
Transgenic LacZ under control of Hec-6st regulatory sequences recapitulates endogenous gene expression on high endothelial venules.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(11):4577-82.
2007: Chimge Nyam-Osor; Ruddle Frank; Bayarsaihan Dashzeveg
Laser-assisted microdissection (LAM) in developmental biology.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2007;308(2):113-8.
2007: Lei Haiyan; Juan Aster H; Kim Moo-Sang; Ruddle Frank H
Mouse naked cuticle 2 (mNkd2) as a direct transcriptional target of Hoxc8 in vivo.
Journal of experimental zoology. Part A, Ecological genetics and physiology 2007;307(1):1-6.
2006: Lei Haiyan; Juan Aster H; Kim Moo-Sang; Ruddle Frank H
Identification of a Hoxc8-regulated transcriptional network in mouse embryo fibroblast cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10305-9.
2006: Juan Aster H; Lei Haiyan; Bhargava Prerna; Lebrun Marielle; Ruddle Frank H
Multiple roles of hoxc8 in skeletal development.
Annals of the New York Academy of Sciences 2006;1068():87-94.
2005: Makeyev Aleksandr V; Kim Chang Bae; Ruddle Frank H; Enkhmandakh Badam; Erdenechimeg Lkhamsuren; Bayarsaihan Dashzeveg
HnRNP A3 genes and pseudogenes in the vertebrate genomes.
Journal of experimental zoology. Part A, Comparative experimental biology 2005;303(4):259-71.
2005: Lei Haiyan; Wang Hailong; Juan Aster H; Ruddle Frank H
The identification of Hoxc8 target genes.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(7):2420-4.
2004: Stadler Peter F; Fried Claudia; Prohaska Sonja J; Bailey Wendy J; Misof Bernhard Y; Ruddle Frank H; Wagner Günter P
Evidence for independent Hox gene duplications in the hagfish lineage: a PCR-based gene inventory of Eptatretus stoutii.
Molecular phylogenetics and evolution 2004;32(3):686-94.
2004: Makeyev Aleksandr V; Erdenechimeg Lkhamsuren; Mungunsukh Ognoon; Roth Jutta J; Enkhmandakh Badam; Ruddle Frank H; Bayarsaihan Dashzeveg
GTF2IRD2 is located in the Williams-Beuren syndrome critical region 7q11.23 and encodes a protein with two TFII-I-like helix-loop-helix repeats.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(30):11052-7.
2004: Ruddle Frank H
Theophilus Painter: First steps toward an understanding of the human genome.
Journal of experimental zoology. Part A, Comparative experimental biology 2004;301(5):375-7.
2004: Prohaska Sonja J; Fried Claudia; Amemiya Chris T; Ruddle Frank H; Wagner Günter P; Stadler Peter F
The shark HoxN cluster is homologous to the human HoxD cluster.
Journal of molecular evolution 2004;58(2):212-7.
2004: Chiu Chi-Hua; Dewar Ken; Wagner Günter P; Takahashi Kazuhiko; Ruddle Frank; Ledje Christina; Bartsch Peter; Scemama Jean-Luc; Stellwag Edmund; Fried Claudia; Prohaska Sonja J; Stadler Peter F; Amemiya Chris T
Bichir HoxA cluster sequence reveals surprising trends in ray-finned fish genomic evolution.
Genome research 2004;14(1):11-7.
2004: Enkhmandakh Badam; Bitchevaia Natalia; Ruddle Frank; Bayarsaihan Dashzeveg
The early embryonic expression of TFII-I during mouse preimplantation development.
Gene expression patterns : GEP 2004;4(1):25-8.
2003: Chiba Shigeru; Takeshita Kenichi; Imai Yoichi; Kumano Keiki; Kurokawa Mineo; Masuda Shigeo; Shimizu Kiyoshi; Nakamura Shuji; Ruddle Frank H; Hirai Hisamaru
Homeoprotein DLX-1 interacts with Smad4 and blocks a signaling pathway from activin A in hematopoietic cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15577-82.
2003: Wagner Gunte P; Amemiya Chris; Ruddle Frank
Hox cluster duplications and the opportunity for evolutionary novelties.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14603-6.
2003: Bayarsaihan Dashzeveg; Bitchevaia Natalia; Enkhmandakh Badam; Tussie-Luna Maria Isabel; Leckman James F; Roy Ananda; Ruddle Frank
Expression of BEN, a member of TFII-I family of transcription factors, during mouse pre- and postimplantation development.
Gene expression patterns : GEP 2003;3(5):579-89.
2003: Juan Aster H; Ruddle Frank H
Enhancer timing of Hox gene expression: deletion of the endogenous Hoxc8 early enhancer.
Development (Cambridge, England) 2003;130(20):4823-34.
2003: Bayarsaihan Dashzeveg; Enkhmandakh Badam; Makeyev Aleksandr; Greally John M; Leckman James F; Ruddle Frank H
Homez, a homeobox leucine zipper gene specific to the vertebrate lineage.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10358-63.
2003: Shashikant Cooduvalli S; Ruddle Frank H
Impact of transgenic technologies on functional genomics.
Current issues in molecular biology 2003;5(3):75-98.
2003: Sumiyama Kenta; Ruddle Frank H
Regulation of Dlx3 gene expression in visceral arches by evolutionarily conserved enhancer elements.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4030-4.
2003: Kim Chang-Bae; Shashikant Cooduvalli S; Sumiyama Kenta; Wang Wayne C H; Amemiya Chris T; Ruddle Frank H
Phylogenetic analysis of the mammalian Hoxc8 non-coding region.
Journal of structural and functional genomics 2003;3(1-4):195-9.
2003: Sumiyama Kenta; Irvine Steven Q; Ruddle Frank H
The role of gene duplication in the evolution and function of the vertebrate Dlx/distal-less bigene clusters.
Journal of structural and functional genomics 2003;3(1-4):151-9.
2002: Tussié-Luna María Isabel; Bayarsaihan Dashzeveg; Seto Edward; Ruddle Frank H; Roy Ananda L
Physical and functional interactions of histone deacetylase 3 with TFII-I family proteins and PIASxbeta.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):12807-12.
2002: Ledje Christina; Kim Chang-Bae; Ruddle Francis H
Characterization of Hox genes in the bichir, Polypterus palmas.
The Journal of experimental zoology 2002;294(2):107-11.
2002: Chiu Chi-hua; Amemiya Chris; Dewar Ken; Kim Chang-Bae; Ruddle Frank H; Wagner Günter P
Molecular evolution of the HoxA cluster in the three major gnathostome lineages.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5492-7.
2002: Irvine Steven Q; Carr Janet L; Bailey Wendy J; Kawasaki Kazuhiko; Shimizu Nobuyoshi; Amemiya Chris T; Ruddle Frank H
Genomic analysis of Hox clusters in the sea lamprey Petromyzon marinus.
The Journal of experimental zoology 2002;294(1):47-62.
2002: Bayarsaihan Dashzeveg; Dunai Judit; Greally John M; Kawasaki Kazuhiko; Sumiyama Kenta; Enkhmandakh Badam; Shimizu Nobuyoshi; Ruddle Frank H
Genomic organization of the genes Gtf2ird1, Gtf2i, and Ncf1 at the mouse chromosome 5 region syntenic to the human chromosome 7q11.23 Williams syndrome critical region.
Genomics 2002;79(1):137-43.
2002: Sumiyama Kenta; Irvine Steven Q; Stock David W; Weiss Kenneth M; Kawasaki Kazuhiko; Shimizu Nobuyoshi; Shashikant Cooduvalli S; Miller Webb; Ruddle Frank H
Genomic structure and functional control of the Dlx3-7 bigene cluster.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):780-5.
2001: Tussié-Luna M I; Bayarsaihan D; Ruddle F H; Roy A L
Repression of TFII-I-dependent transcription by nuclear exclusion.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(14):7789-94.
2001: Sumiyama K; Kim C B; Ruddle F H
An efficient cis-element discovery method using multiple sequence comparisons based on evolutionary relationships.
Genomics 2001;71(2):260-2.
2001: Ruddle F
Hundred-year search for the human genome.
Annual review of genomics and human genetics 2001;2():1-8.
2000: Bayarsaihan D; Ruddle F H
Isolation and characterization of BEN, a member of the TFII-I family of DNA-binding proteins containing distinct helix-loop-helix domains.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(13):7342-7.
2000: Kim C B; Amemiya C; Bailey W; Kawasaki K; Mezey J; Miller W; Minoshima S; Shimizu N; Wagner G; Ruddle F
Hox cluster genomics in the horn shark, Heterodontus francisci.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(4):1655-60.
2000: Chiu C H; Amemiya C T; Carr J L; Bhargava J; Hwang J K; Shashikant C S; Ruddle F H; Wagner G P
A recombinogenic targeting method to modify large-inserts for cis-regulatory analysis in transgenic mice: construction and expression of a 100-kb, zebrafish Hoxa-11b-lacZ reporter gene.
Development genes and evolution 2000;210(2):105-9.
1999: Bhargava J; Shashikant C S; Carr J L; Juan H; Bentley K L; Ruddle F H
Direct cloning of genomic DNA by recombinogenic targeting method using a yeast-bacterial shuttle vector, pClasper.
Genomics 1999;62(2):285-8.
1999: Hanson R D; Hess J L; Yu B D; Ernst P; van Lohuizen M; Berns A; van der Lugt N M; Shashikant C S; Ruddle F H; Seto M; Korsmeyer S J
Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14372-7.
1999: Igarashi P; Shashikant C S; Thomson R B; Whyte D A; Liu-Chen S; Ruddle F H; Aronson P S
Ksp-cadherin gene promoter. II. Kidney-specific activity in transgenic mice.
The American journal of physiology 1999;277(4 Pt 2):F599-610.
1999: Deinard A; Dorit R; Castiglione C; Jiang Z; Becker D; Ruddle F; Schugart K; Kidd K
Evolution of the HOXB6 intergenic region: motif conservation at the lateral plate mesoderm (LPM) enhancer element.
The Journal of experimental zoology 1999;285(2):170-6.
1999: Ruddle F H; Amemiya C T; Carr J L; Kim C B; Ledje C; Shashikant C S; Wagner G P
Evolution of chordate hox gene clusters.
Annals of the New York Academy of Sciences 1999;870():238-48.
1999: Fienberg A A; Nordstedt C; Belting H G; Czernik A J; Nairn A C; Gandy S; Greengard P; Ruddle F H
Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6.
The Journal of experimental zoology 1999;285(1):76-84.
1999: Bhargava J; Shashikant C S; Carr J L; Bentley K L; Amemiya C T; Ruddle F H
pPAC-ResQ: A yeast-bacterial shuttle vector for capturing inserts from P1 and PAC clones by recombinogenic targeted cloning.
Genomics 1999;56(3):337-9.
1998: Ruddle F H
Mapping and sequencing of the human genome.
Japanese journal of cancer research : Gann 1998;89(12):inside front cover.
1998: Shashikant C S; Kim C B; Borbély M A; Wang W C; Ruddle F H
Comparative studies on mammalian Hoxc8 early enhancer sequence reveal a baleen whale-specific deletion of a cis-acting element.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15446-51.
1998: Shashikant C S; Carr J L; Bhargava J; Bentley K L; Ruddle F H
Recombinogenic targeting: a new approach to genomic analysis--a review.
Gene 1998;223(1-2):9-20.
1998: Belting H G; Shashikant C S; Ruddle F H
Multiple phases of expression and regulation of mouse Hoxc8 during early embryogenesis.
The Journal of experimental zoology 1998;282(1-2):196-222.
1998: Belting H G; Shashikant C S; Ruddle F H
Modification of expression and cis-regulation of Hoxc8 in the evolution of diverged axial morphology.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2355-60.
1998: Carr J L; Shashikant C S; Bailey W J; Ruddle F H
Molecular evolution of Hox gene regulation: cloning and transgenic analysis of the lamprey HoxQ8 gene.
The Journal of experimental zoology 1998;280(1):73-85.
1997: Ruddle F H
Vertebrate genome evolution--the decade ahead.
Genomics 1997;46(2):171-3.
1997: Bailey W J; Kim J; Wagner G P; Ruddle F H
Phylogenetic reconstruction of vertebrate Hox cluster duplications.
Molecular biology and evolution 1997;14(8):843-53.
1996: Nakamura S; Stock D W; Wydner K L; Bollekens J A; Takeshita K; Nagai B M; Chiba S; Kitamura T; Freeland T M; Zhao Z; Minowada J; Lawrence J B; Weiss K M; Ruddle F H
Genomic analysis of a new mammalian distal-less gene: Dlx7.
Genomics 1996;38(3):314-24.
1996: Shashikant C S; Ruddle F H
Combinations of closely situated cis-acting elements determine tissue-specific patterns and anterior extent of early Hoxc8 expression.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12364-9.
1996: Lu S; Shashikant C S; Ruddle F H
Separate cis-acting elements determine the expression of mouse Dbx gene in multiple spatial domains of the central nervous system.
Mechanisms of development 1996;58(1-2):193-202.
1996: Bradshaw M S; Shashikant C S; Belting H G; Bollekens J A; Ruddle F H
A long-range regulatory element of Hoxc8 identified by using the pClasper vector.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(6):2426-30.
1996: Friedman-Einat M; Einat P; Snyder M; Ruddle F
Target gene identification: target specific transcriptional activation by three murine homeodomain/VP16 hybrid proteins in Saccharomyces cerevisiae.
The Journal of experimental zoology 1996;274(3):145-56.
1996: Lin X; Swaroop A; Vaccarino F M; Murtha M T; Haas M; Ji X; Ruddle F H; Leckman J F
Characterization and sequence analysis of the human homeobox-containing gene GBX2.
Genomics 1996;31(3):335-42.
1996: Becker D; Jiang Z; Knödler P; Deinard A S; Eid R; Kidd K K; Shashikant C S; Ruddle F H; Schughart K
Conserved regulatory element involved in the early onset of Hoxb6 gene expression.
Developmental dynamics : an official publication of the American Association of Anatomists 1996;205(1):73-81.
1996: Gardner D P; Byrne G W; Ruddle F H; Kappen C
Spatial and temporal regulation of a lacZ reporter transgene in a binary transgenic mouse system.
Transgenic research 1996;5(1):37-48.
1995: Shashikant C S; Bieberich C J; Belting H G; Wang J C; Borbély M A; Ruddle F H
Regulation of Hoxc-8 during mouse embryonic development: identification and characterization of critical elements involved in early neural tube expression.
Development (Cambridge, England) 1995;121(12):4339-47.
1995: Bradshaw M S; Bollekens J A; Ruddle F H
A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes.
Nucleic acids research 1995;23(23):4850-6.
1995: Bentley K L; Bradshaw M S; Ruddle F H
Human HOXB cluster and the nerve growth factor receptor gene: comparison with an orthologous chromosomal domain in mouse.
Genomics 1995;30(1):18-24.
1995: Weiss K M; Ruddle F H; Bollekens J
Dlx and other homeobox genes in the morphological development of the dentition.
Connective tissue research 1995;32(1-4):35-40.
1994: Weiss K M; Bollekens J; Ruddle F H; Takashita K
Distal-less and other homeobox genes in the development of the dentition.
The Journal of experimental zoology 1994;270(3):273-84.
1994: Lu S; Wise T L; Ruddle F H
Mouse homeobox gene Dbx: sequence, gene structure and expression pattern during mid-gestation.
Mechanisms of development 1994;47(2):187-95.
1994: Roberts M R; Han Y; Fienberg A; Hunihan L; Ruddle F H
A DNA-binding activity, TRAC, specific for the TRA element of the transferrin receptor gene copurifies with the Ku autoantigen.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6354-8.
1994: Bradshaw M S; Ruddle F H
Identification of the murine Hox-c12 and Hox-c13 homeoboxes on yeast artificial chromosomes.
Genomics 1994;22(1):234-6.
1994: Salbaum J M; Ruddle F H
Embryonic expression pattern of amyloid protein precursor suggests a role in differentiation of specific subsets of neurons.
The Journal of experimental zoology 1994;269(2):116-27.
1994: Ruddle F H; Bartels J L; Bentley K L; Kappen C; Murtha M T; Pendleton J W
Evolution of Hox genes.
Annual review of genetics 1994;28():423-42.
1994: Ruddle F H; Bentley K L; Murtha M T; Risch N
Gene loss and gain in the evolution of the vertebrates.
Development (Cambridge, England). Supplement 1994;():155-61.
1993: Kappen C; Ruddle F H
Evolution of a regulatory gene family: HOM/HOX genes.
Current opinion in genetics & development 1993;3(6):931-8.
1993: Kappen C; Schughart K; Ruddle F H
Early evolutionary origin of major homeodomain sequence classes.
Genomics 1993;18(1):54-70.
1993: Bentley K L; Bradshaw M S; Ruddle F H
Physical linkage of the murine Hox-b cluster and nerve growth factor receptor on yeast artificial chromosomes.
Genomics 1993;18(1):43-53.
1993: Malicki J; Bogarad L D; Martin M M; Ruddle F H; McGinnis W
Functional analysis of the mouse homeobox gene HoxB9 in Drosophila development.
Mechanisms of development 1993;42(3):139-50.
1993: Pendleton J W; Nagai B K; Murtha M T; Ruddle F H
Expansion of the Hox gene family and the evolution of chordates.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(13):6300-4.
1993: Bartels J L; Murtha M T; Ruddle F H
Multiple Hox/HOM-class homeoboxes in Platyhelminthes.
Molecular phylogenetics and evolution 1993;2(2):143-51.
1993: Takeshita K; Bollekens J A; Hijiya N; Ratajczak M; Ruddle F H; Gewirtz A M
A homeobox gene of the Antennapedia class is required for human adult erythropoiesis.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3535-8.
1992: Lu S; Bogarad L D; Murtha M T; Ruddle F H
Expression pattern of a murine homeobox gene, Dbx, displays extreme spatial restriction in embryonic forebrain and spinal cord.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8053-7.
1992: Hart C P; Compton J G; Langley S H; Hunihan L; LeClair K P; Zelent A; Roderick T H; Ruddle F H
Genetic linkage analysis of the murine developmental mutant velvet coat (Ve) and the distal chromosome 15 developmental genes Hox-3.1, Rar-g, Wnt-1, and Krt-2.
The Journal of experimental zoology 1992;263(1):83-95.
1992: Violette S M; Shashikant C S; Salbaum J M; Belting H G; Wang J C; Ruddle F H
Repression of the beta-amyloid gene in a Hox-3.1-producing cell line.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):3805-9.
1992: Ruddle F H
Yoshio Okada: father of warm fusion.
Japanese journal of cancer research : Gann 1992;83(3):inside front cover.
1991: Murtha M T; Leckman J F; Ruddle F H
Detection of homeobox genes in development and evolution.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10711-5.
1991: Schierwater B; Murtha M; Dick M; Ruddle F H; Buss L W
Homeoboxes in cnidarians.
The Journal of experimental zoology 1991;260(3):413-6.
1991: Schughart K; Bieberich C J; Eid R; Ruddle F H
A regulatory region from the mouse Hox-2.2 promoter directs gene expression into developing limbs.
Development (Cambridge, England) 1991;112(3):807-11.
1991: Pravtcheva D D; Adra C N; Ruddle F H
Timing of paternal Pgk-1 expression in embryos of transgenic mice.
Development (Cambridge, England) 1991;111(4):1109-20.
1991: Pendleton J W; Violette S M; Hunihan L W; Greene L A; Ruddle F H
The peripherin gene maps to mouse chromosome 15.
Genomics 1991;9(2):369-72.
1991: Shashikant C S; Utset M F; Violette S M; Wise T L; Einat P; Einat M; Pendleton J W; Schughart K; Ruddle F H
Homeobox genes in mouse development.
Critical reviews in eukaryotic gene expression 1991;1(3):207-45.
1991: Byrne G W; Kappen C; Schughart K; Utset M; Bogarad L; Ruddle F H
Analysis of regulatory genes using the transgenic mouse system.
Biotechnology (Reading, Mass.) 1991;16():135-52.
1990: Bieberich C J; Utset M F; Awgulewitsch A; Ruddle F H
Evidence for positive and negative regulation of the Hox-3.1 gene.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8462-6.
1990: Awgulewitsch A; Bieberich C; Bogarad L; Shashikant C; Ruddle F H
Structural analysis of the Hox-3.1 transcription unit and the Hox-3.2--Hox-3.1 intergenic region.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(16):6428-32.
1990: Ruano G; Gray M R; Miki T; Ferguson-Smith A C; Ruddle F H; Kidd K K
Monomorphism in humans and sequence differences among higher primates for a sequence tagged site (STS) in homeo box cluster 2 as assayed by denaturing gradient electrophoresis.
Nucleic acids research 1990;18(5):1314.
1990: Le Bouteiller P; Bogarad L D; Roberts M R; Barbosa J A; Ruddle F H
Binding of nuclear factors to the 5'-interferon consensus sequence of the HLA-A2 class I gene.
Experimental cell research 1990;186(2):203-9.
1989: Roberts M R; Miskimins W K; Ruddle F H
Nuclear proteins TREF1 and TREF2 bind to the transcriptional control element of the transferrin receptor gene and appear to be associated as a heterodimer.
Cell regulation 1989;1(1):151-64.
1989: Pravtcheva D; Newman M; Hunihan L; Lonai P; Ruddle F H
Chromosome assignment of the murine Hox-4.1 gene.
Genomics 1989;5(3):541-5.
1989: Schughart K; Kappen C; Ruddle F H
Duplication of large genomic regions during the evolution of vertebrate homeobox genes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(18):7067-71.
1989: Ferguson-Smith A C; Fienberg A; Ruddle F H
Isolation, chromosomal localization, and nucleotide sequence of the human HOX 1.4 homeobox.
Genomics 1989;5(2):250-8.
1989: Opdenakker G; Snoddy J; Choubey D; Toniato E; Pravtcheva D D; Seldin M F; Ruddle F H; Lengyel P
Interferons as gene activators: a cluster of six interferon-activatable genes is linked to the erythroid alpha-spectrin locus on murine chromosome 1.
Virology 1989;171(2):568-78.
1989: Schughart K; Pravtcheva D; Newman M S; Hunihan L W; Jiang Z L; Ruddle F H
Isolation and regional localization of the murine homeobox-containing gene Hox-3.3 to mouse chromosome region 15E.
Genomics 1989;5(1):76-83.
1989: Byrne G W; Ruddle F H
Multiplex gene regulation: a two-tiered approach to transgene regulation in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5473-7.
1989: Kappen C; Schughart K; Ruddle F H
Two steps in the evolution of Antennapedia-class vertebrate homeobox genes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5459-63.
1989: Bogarad L D; Utset M F; Awgulewitsch A; Miki T; Hart C P; Ruddle F H
The developmental expression pattern of a new murine homeo box gene: Hox-2.5.
Developmental biology 1989;133(2):537-49.
1989: Ruddle F H
Tribute to Torbjörn Caspersson.
American journal of human genetics 1989;44(4):439-40.
1989: Kappen C; Schughart K; Ruddle F H
Organization and expression of homeobox genes in mouse and man.
Annals of the New York Academy of Sciences 1989;567():243-52.
1988: Lieberman H B; Lin P F; Yeh D B; Ruddle F H
Transcriptional and posttranscriptional mechanisms regulate murine thymidine kinase gene expression in serum-stimulated cells.
Molecular and cellular biology 1988;8(12):5280-91.
1988: Schughart K; Kappen C; Ruddle F H
Mammalian homeobox-containing genes: genome organization, structure, expression and evolution.
The British journal of cancer. Supplement 1988;9():9-13.
1988: Schughart K; Utset M F; Awgulewitsch A; Ruddle F H
Structure and expression of Hox-2.2, a murine homeobox-containing gene.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(15):5582-6.
1988: Miki T; Nishisho I; Tateishi H; Chen Y; Kidd J R; Wu J; Pravtcheva D; Pakstis A J; Takai S; Ruddle F H
D10S20, a previously unmapped RFLP (OS-3), is located on 10q near D10S4.
Genomics 1988;3(1):78-81.
1988: Ferguson-Smith A C; Chen Y F; Newman M S; May L T; Sehgal P B; Ruddle F H
Regional localization of the interferon-beta 2/B-cell stimulatory factor 2/hepatocyte stimulating factor gene to human chromosome 7p15-p21.
Genomics 1988;2(3):203-8.
1988: Hart C P; Dalton D K; Nichols L; Hunihan L; Roderick T H; Langley S H; Taylor B A; Ruddle F H
The Hox-2 homeo box gene complex on mouse chromosome 11 is closely linked to Re.
Genetics 1988;118(2):319-27.
1988: Bentley K L; Ferguson-Smith A C; Ruddle F H
A review of genomic physical mapping.
Cancer surveys 1988;7(2):267-94.
1988: Ferguson-Smith A C; Ruddle F H
The genomics of human homeobox-containing loci.
Pathology and immunopathology research 1988;7(1-2):119-26.
1987: Lumadue J A; Glick A B; Ruddle F H
Cloning, sequence analysis, and expression of the large subunit of the human lymphocyte activation antigen 4F2.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):9204-8.
1987: Fainsod A; Awgulewitsch A; Ruddle F H
Expression of the murine homeo box gene Hox 1.5 during embryogenesis.
Developmental biology 1987;124(1):125-33.
1987: Hart C P; Fainsod A; Ruddle F H
Sequence analysis of the murine Hox-2.2, -2.3, and -2.4 homeo boxes: evolutionary and structural comparisons.
Genomics 1987;1(2):182-95.
1987: Murphy P D; Lin P F; Ruddle F H; Kidd K K
A second useful polymorphism for the cytosolic thymidine kinase gene (TK1) with the enzyme BstEII which will allow haplotying at this locus on chromosome 17 (q21-q22).
Nucleic acids research 1987;15(17):7212.
1987: Ruddle F
Developmental genetics: new approaches and opportunities.
Somatic cell and molecular genetics 1987;13(4):467.
1987: Hart C P; Bogarad L D; Fainsod A; Ruddle F H
Polypurine/polypyrimidine sequence elements of the murine homeo box loci, Hox-1, -2 and -3.
Nucleic acids research 1987;15(13):5495.
1987: LeClair K P; Rabin M; Nesbitt M N; Pravtcheva D; Ruddle F H; Palfree R G; Bothwell A
Murine Ly-6 multigene family is located on chromosome 15.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(6):1638-42.
1987: Utset M F; Awgulewitsch A; Ruddle F H; McGinnis W
Region-specific expression of two mouse homeo box genes.
Science (New York, N.Y.) 1987;235(4794):1379-82.
1987: Lin P F; Brown D B; Murphy P; Yamaizumi M; Ruddle F H
Detection and characterization of specific mRNA by microinjection and complementation of mutant cells.
Methods in enzymology 1987;151():371-82.
1987: Fienberg A A; Utset M F; Bogarad L D; Hart C P; Awgulewitsch A; Ferguson-Smith A; Fainsod A; Rabin M; Ruddle F H
Homeo box genes in murine development.
Current topics in developmental biology 1987;23():233-56.
1986: Fainsod A; Bogarad L D; Ruusala T; Lubin M; Crothers D M; Ruddle F H
The homeo domain of a murine protein binds 5' to its own homeo box.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(24):9532-6.
1986: Rabin M; Ferguson-Smith A; Hart C P; Ruddle F H
Cognate homeo-box loci mapped on homologous human and mouse chromosomes.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(23):9104-8.
1986: Sehgal P B; Zilberstein A; Ruggieri R M; May L T; Ferguson-Smith A; Slate D L; Revel M; Ruddle F H
Human chromosome 7 carries the beta 2 interferon gene.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(14):5219-22.
1986: Murphy P D; Kidd J R; Castiglione C M; Lin P F; Ruddle F H; Kidd K K
A frequent polymorphism for the cytosolic thymidine kinase gene, TK1, (17q21-q22) detected by the enzyme TaqI.
Nucleic acids research 1986;14(10):4381.
1986: Awgulewitsch A; Utset M F; Hart C P; McGinnis W; Ruddle F H
Spatial restriction in expression of a mouse homoeo box locus within the central nervous system.
Nature 1986;320(6060):328-35.
1985: Lin P F; Lieberman H B; Yeh D B; Xu T; Zhao S Y; Ruddle F H
Molecular cloning and structural analysis of murine thymidine kinase genomic and cDNA sequences.
Molecular and cellular biology 1985;5(11):3149-56.
1985: Hart C P; Awgulewitsch A; Fainsod A; McGinnis W; Ruddle F H
Homeo box gene complex on mouse chromosome 11: molecular cloning, expression in embryogenesis, and homology to a human homeo box locus.
Cell 1985;43(1):9-18.
1985: Sagar A D; Sehgal P B; May L T; Slate D L; Shulman L; Barker P E; Ruddle F H
Interferon-beta-related DNA on human chromosome 4.
Somatic cell and molecular genetics 1985;11(4):403-8.
1985: Murphy P D; Kidd J R; Breg W R; Ruddle F H; Kidd K K
An anonymous single copy X-chromosome clone, DXS79, from Xq26-Xq28, identifies a moderately frequent RFLP [HGM8 provisional no. DXS79].
Nucleic acids research 1985;13(8):3015.
1985: Rabin M; Hart C P; Ferguson-Smith A; McGinnis W; Levine M; Ruddle F H
Two homoeo box loci mapped in evolutionarily related mouse and human chromosomes.
Nature 1985;314(6007):175-8.
1985: Ruddle F H; Hart C P; Awgulewitsch A; Fainsod A; Utset M; Dalton D; Kerk N; Rabin M; Ferguson-Smith A; Fienberg A
Mammalian homeo box genes.
Cold Spring Harbor symposia on quantitative biology 1985;50():277-84.
1984: McGinnis W; Hart C P; Gehring W J; Ruddle F H
Molecular cloning and chromosome mapping of a mouse DNA sequence homologous to homeotic genes of Drosophila.
Cell 1984;38(3):675-80.
1984: Sagar A D; Sehgal P B; May L T; Inouye M; Slate D L; Shulman L; Ruddle F H
Interferon-beta-related DNA is dispersed in the human genome.
Science (New York, N.Y.) 1984;223(4642):1312-5.
1984: Samanta H; Pravtcheva D D; Ruddle F H; Lengyel P
Chromosomal location of mouse gene 202 which is induced by interferons and specifies a 56.5 kD protein.
Journal of interferon research 1984;4(2):295-300.
1983: Lin P F; Zhao S Y; Ruddle F H
Genomic cloning and preliminary characterization of the human thymidine kinase gene.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(21):6528-32.
1982: Sagar A D; Sehgal P B; Slate D L; Ruddle F H
Multiple human beta interferon genes.
The Journal of experimental medicine 1982;156(3):744-55.
1982: Lin P F; Yamaizumi M; Murphy P D; Egg A; Ruddle F H
Partial purification and characterization of the mRNA for human thymidine kinase and hypoxanthine/guanine phosphoribosyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(14):4290-4.
1981: Huttner K M; Barbosa J A; Scangos G A; Pratcheva D D; Ruddle F H
DNA-mediated gene transfer without carrier DNA.
The Journal of cell biology 1981;91(1):153-6.
1981: Scangos G A; Huttner K M; Juricek D K; Ruddle F H
Deoxyribonucleic acid-mediated gene transfer in mammalian cells: molecular analysis of unstable transformants and their progression to stability.
Molecular and cellular biology 1981;1(2):111-20.
1980: Gordon J W; Scangos G A; Plotkin D J; Barbosa J A; Ruddle F H
Genetic transformation of mouse embryos by microinjection of purified DNA.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7380-4.

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