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Hartmut Ruetten

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TOP 3
Sven Ruf; Herman Schreuder; Klaus Wirth; Christian Buning; Thomas Hübschle; Dominik Linz; Wolfgang Linz; Hartmut Ruetten; Thorsten Sadowski
Inhibition of CatA: an emerging strategy for the treatment of heart failure.
Klaus J Wirth; Klaus Steinmeyer; Hartmut Ruetten
Sensitization of Upper Airway Mechanoreceptors as a New Pharmacologic Principle to Treat Obstructive Sleep Apnea: Investigations with AVE0118 in Anesthetized Pigs.
Paulus Wohlfart; Ulrich Werner; Daniel Crowther; Sibylle Hess; Jochen Huber; Thomas Hübschle; Dominik Linz; Wolfgang Linz; Hartmut Ruetten
Cardioprotective effects of lixisenatide in rat myocardial ischemia-reperfusion injury studies.

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All Publications

2013: Sven Ruf; Herman Schreuder; Klaus Wirth; Christian Buning; Thomas Hübschle; Dominik Linz; Wolfgang Linz; Hartmut Ruetten; Thorsten Sadowski
Inhibition of CatA: an emerging strategy for the treatment of heart failure.
Future medicinal chemistry 2013;5(4):399-409.
2013: Klaus J Wirth; Klaus Steinmeyer; Hartmut Ruetten
Sensitization of Upper Airway Mechanoreceptors as a New Pharmacologic Principle to Treat Obstructive Sleep Apnea: Investigations with AVE0118 in Anesthetized Pigs.
Sleep 2013;36(5):699-708.
2013: Paulus Wohlfart; Ulrich Werner; Daniel Crowther; Sibylle Hess; Jochen Huber; Thomas Hübschle; Dominik Linz; Wolfgang Linz; Hartmut Ruetten
Cardioprotective effects of lixisenatide in rat myocardial ischemia-reperfusion injury studies.
Journal of translational medicine 2013;11():84.
2012: Dominik Linz; Wolfgang Linz; Uwe Schwahn; Klaus Wirth; Petra Arndt; Michael Böhm; Wendelin Frick; Uwe Heinelt; Hubert O O Heuer; Armin Hofmeister; Hartmut Ruetten
Antihypertensive and laxative effects by pharmacological inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut.
Hypertension 2012;60(6):1560-7.
2012: George E Billman; Heinz Gögelein; Hartmut Ruetten; Klaus J Wirth
Effects of a novel amiodarone-like compound SAR114646A on the pig atrium and susceptibility to ventricular fibrillation in dogs and pigs.
Naunyn-Schmiedeberg's archives of pharmacology 2012;385(4):373-84.
2011: Heinz Goegelein; Stephen O'Connor; Alain Roccon; Patrick Gautier; Hartmut Ruetten
Effects of the novel amiodarone-like compound SAR114646A on cardiac ion channels and ventricular arrhythmias in rats.
Naunyn-Schmiedeberg's archives of pharmacology 2011;384(3):231-44.
2011: Roman Bogdan; Heinz Goegelein; Hartmut Ruetten
Effect of dronedarone on Na+, Ca2+ and HCN channels.
Naunyn-Schmiedeberg's archives of pharmacology 2011;383(4):347-56.
2010: Andreas Schäfer; Paolo Galuppo; Daniela Fraccarollo; Christian Vogt; Julian D Widder; Julia Pfrang; Piet Tas; Eduardo Barbosa-Sicard; Hartmut Ruetten; Georg Ertl; Ingrid Fleming; Johann Bauersachs
Increased cytochrome P4502E1 expression and altered hydroxyeicosatetraenoic acid formation mediate diabetic vascular dysfunction: rescue by guanylyl-cyclase activation.
Diabetes 2010;59(8):2001-9.
2009: Stefan Frantz; Anna Adamek; D Fraccarollo; Jochen Tillmanns; J D Widder; Charlotte Dienesch; A Schäfer; A Podolskaya; M Held; Hartmut Ruetten; Georg Ertl; Johann Bauersachs
The eNOS enhancer AVE 9488: a novel cardioprotectant against ischemia reperfusion injury.
Basic research in cardiology 2009;104(6):773-9.
2009: Matthias Löhn; Oliver Plettenburg; Yuri Ivashchenko; Aimo Kannt; Armin Hofmeister; Dieter Kadereit; Matthias Schaefer; Wolfgang Linz; Markus Kohlmann; Jean-Marc Herbert; Philip Janiak; Stephen E O'Connor; Hartmut Ruetten
Pharmacological characterization of SAR407899, a novel rho-kinase inhibitor.
Hypertension 2009;54(3):676-83.
2008: Daniela Fraccarollo; Julian Widder; Paolo Galuppo; Thomas Thum; Dimitrios Tsikas; Michael Hoffmann; Hartmut Ruetten; Georg Ertl; Johann Bauersachs
Improvement in left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction.
Circulation 2008;118(8):818-27.
2008: Paulus Wohlfart; Hui Xu; Alexandra Endlich; Alice Habermeier; Ellen I Closs; Thomas Hübschle; Christian Mang; Hartmut Strobel; Teri Suzuki; Hartmut Kleinert; Ulrich Förstermann; Hartmut Ruetten; Huige Li
Antiatherosclerotic effects of small-molecular-weight compounds enhancing endothelial nitric-oxide synthase (eNOS) expression and preventing eNOS uncoupling.
The Journal of pharmacology and experimental therapeutics 2008;325(2):370-9.
2006: Johann Bauersachs; Katrin Hiss; Daniela Fraccarollo; Ulrich Laufs; Hartmut Ruetten
Simvastatin improves left ventricular function after myocardial infarction in hypercholesterolemic rabbits by anti-inflammatory effects.
Cardiovascular research 2006;72(3):438-46.
2006: Katrin Hiss; Kerstin Steioff; Matthias Loehn; Hartmut Ruetten
Transcutaneous vascular ultrasound in hypercholesterolaemic rabbits: a new method to evaluate endothelial function.
Laboratory animals 2006;40(1):80-6.
2005: Hartmut Ruetten; Doris Gehring; Katrin Hiss; Ursula Schindler; Martin Gerl; Andreas E Busch; Stefan Schaefer
Effects of combined inhibition of the Na+-H+ exchanger and angiotensin-converting enzyme in rats with congestive heart failure after myocardial infarction.
British journal of pharmacology 2005;146(5):723-31.
2005: Hartmut Ruetten; Stefanie Dimmeler; Doris Gehring; Christian Ihling; Andreas M Zeiher
Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload.
Cardiovascular research 2005;66(3):444-53.
2005: Jörg Heineke; Hartmut Ruetten; Christian Willenbockel; Sandra C Gross; Marian Naguib; Arnd Schaefer; Tibor Kempf; Denise Hilfiker-Kleiner; Pico Caroni; Theresia Kraft; Robert A Kaiser; Jeffery D Molkentin; Helmut Drexler; Kai C Wollert
Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1655-60.
2004: Katrin Rungwerth; Ursula Schindler; Martin Gerl; Stefan Schäfer; Thomas Licher; Andreas E Busch; Hartmut Ruetten
Inhibition of Na+-H+ exchange by cariporide reduces inflammation and heart failure in rabbits with myocardial infarction.
British journal of pharmacology 2004;142(7):1147-54.
2002: Cornel Badorff; Hartmut Ruetten; Sven Mueller; Meike Stahmer; Doris Gehring; Frank Jung; Christian Ihling; Andreas M Zeiher; Stefanie Dimmeler
Fas receptor signaling inhibits glycogen synthase kinase 3 beta and induces cardiac hypertrophy following pressure overload.
The Journal of clinical investigation 2002;109(3):373-81.
2001: Hartmut Ruetten; Cornel Badorff; Christian Ihling; Andreas M Zeiher; Stefanie Dimmeler
Inhibition of caspase-3 improves contractile recovery of stunned myocardium, independent of apoptosis-inhibitory effects.
Journal of the American College of Cardiology 2001;38(7):2063-70.
2001: Heinz Gögelein; Hartmut Ruetten; Udo Albus; Heinrich C Englert; Andreas E Busch
Effects of the cardioselective KATP channel blocker HMR 1098 on cardiac function in isolated perfused working rat hearts and in anesthetized rats during ischemia and reperfusion.
Naunyn-Schmiedeberg's archives of pharmacology 2001;364(1):33-41.
2001: Pierre Meneton; May Bloch-Faure; Albert A Hagege; Hartmut Ruetten; W Huang; Sonia Bergaya; D Ceiler; Doris Gehring; I Martins; G Salmon; Chantal M Boulanger; J Nussberger; Bertrand Crozatier; Jean-Marie Gasc; Didier Heudes; Patrick Bruneval; Thomas Doetschman; Joël Ménard; François Alhenc-Gelas
Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(5):2634-9.
2000: U Weiland; Judith Haendeler; Christian Ihling; Udo Albus; W Scholz; Hartmut Ruetten; Andreas M Zeiher; Stefanie Dimmeler
Inhibition of endogenous nitric oxide synthase potentiates ischemia-reperfusion-induced myocardial apoptosis via a caspase-3 dependent pathway.
Cardiovascular research 2000;45(3):671-8.
1999: Paulus Wohlfart; Tadeusz Malinski; Hartmut Ruetten; Ursula Schindler; Wolfgang Linz; K Schoenafinger; H Strobel; Gabriele Wiemer
Release of nitric oxide from endothelial cells stimulated by YC-1, an activator of soluble guanylyl cyclase.
British journal of pharmacology 1999;128(6):1316-22.
1999: Hartmut Ruetten; U Zabel; Wolfgang Linz; Harald Schmidt
Downregulation of soluble guanylyl cyclase in young and aging spontaneously hypertensive rats.
Circulation research 1999;85(6):534-41.