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Francesca Ruggiero

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Giuseppe Paradies; Valeria Paradies; Francesca M Ruggiero; Giuseppe Petrosillo
Changes in the mitochondrial permeability transition pore in aging and age-associated diseases.
Giuseppe Paradies; Giuseppe Petrosillo; Valeria Paradies; Francesca M Ruggiero
Mitochondrial dysfunction in brain aging: role of oxidative stress and cardiolipin.
Giuseppe Petrosillo; Nicola Di Venosa; N Moro; Giuseppe Colantuono; V Paradies; edy tiravanti; Antonio Federici; Francesca M Ruggiero; Giuseppe Paradies
In vivo hyperoxic preconditioning protects against rat-heart ischemia/reperfusion injury by inhibiting mitochondrial permeability transition pore opening and cytochrome c release.

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All Publications

2013: Giuseppe Paradies; Valeria Paradies; Francesca M Ruggiero; Giuseppe Petrosillo
Changes in the mitochondrial permeability transition pore in aging and age-associated diseases.
Mechanisms of ageing and development 2013;134(1-2):1-9.
2011: Giuseppe Paradies; Giuseppe Petrosillo; Valeria Paradies; Francesca M Ruggiero
Mitochondrial dysfunction in brain aging: role of oxidative stress and cardiolipin.
Neurochemistry international 2011;58(4):447-57.
2011: Giuseppe Petrosillo; Nicola Di Venosa; N Moro; Giuseppe Colantuono; V Paradies; edy tiravanti; Antonio Federici; Francesca M Ruggiero; Giuseppe Paradies
In vivo hyperoxic preconditioning protects against rat-heart ischemia/reperfusion injury by inhibiting mitochondrial permeability transition pore opening and cytochrome c release.
Free radical biology & medicine 2011;50(3):477-83.
2010: Giuseppe Paradies; Giuseppe Petrosillo; Valeria Paradies; Francesca M Ruggiero
Oxidative stress, mitochondrial bioenergetics, and cardiolipin in aging.
Free radical biology & medicine 2010;48(10):1286-95.
2010: Giuseppe Paradies; Giuseppe Petrosillo; Valeria Paradies; Russel J Reiter; Francesca M Ruggiero
Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease.
Journal of pineal research 2010;48(4):297-310.
2010: Giuseppe Petrosillo; Nicola Moro; Valeria Paradies; Francesca M Ruggiero; Giuseppe Paradies
Increased susceptibility to Ca(2+)-induced permeability transition and to cytochrome c release in rat heart mitochondria with aging: effect of melatonin.
Journal of pineal research 2010;48(4):340-6.
2009: Giuseppe Petrosillo; Giuseppe Colantuono; Nicola Moro; Francesca M Ruggiero; edy tiravanti; Nicola Di Venosa; Tommaso Fiore; Giuseppe Paradies
Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening.
American journal of physiology. Heart and circulatory physiology 2009;297(4):H1487-93.
2009: Giuseppe Petrosillo; Nicola Moro; Francesca M Ruggiero; Giuseppe Paradies
Melatonin inhibits cardiolipin peroxidation in mitochondria and prevents the mitochondrial permeability transition and cytochrome c release.
Free radical biology & medicine 2009;47(7):969-74.
2009: Giuseppe Paradies; Giuseppe Petrosillo; Valeria Paradies; Francesca M Ruggiero
Role of cardiolipin peroxidation and Ca2+ in mitochondrial dysfunction and disease.
Cell calcium 2009;45(6):643-50.
2008: Giuseppe Petrosillo; M Matera; Giacoma Casanova; Francesca M Ruggiero; Giuseppe Paradies
Mitochondrial dysfunction in rat brain with aging Involvement of complex I, reactive oxygen species and cardiolipin.
Neurochemistry international 2008;53(5):126-31.
2008: Giuseppe Petrosillo; Patrizia Fattoretti; Mariagiuseppa Matera; Francesca M Ruggiero; Carlo Bertoni-Freddari; Giuseppe Paradies
Melatonin prevents age-related mitochondrial dysfunction in rat brain via cardiolipin protection.
Rejuvenation research 2008;11(5):935-43.
2007: Giuseppe Petrosillo; Giacoma Casanova; Mariagiuseppa Matera; Francesca M Ruggiero; Giuseppe Paradies
Synergistic effect of Ca2+ and peroxidized cardiolipin in the induction of permeability transition and cytochrome c release in rat heart mitochondria.
The Italian journal of biochemistry 2007;56(4):307-9.
2007: Giuseppe Petrosillo; Piero Portincasa; Ignazio Grattagliano; Giacoma Casanova; Mariagiuseppa Matera; Francesca M Ruggiero; Domenico Ferri; Giuseppe Paradies
Mitochondrial dysfunction in rat with nonalcoholic fatty liver Involvement of complex I, reactive oxygen species and cardiolipin.
Biochimica et biophysica acta 2007;1767(10):1260-7.
2006: Giuseppe Petrosillo; Giacoma Casanova; Mariagiuseppa Matera; Francesca M Ruggiero; Giuseppe Paradies
Interaction of peroxidized cardiolipin with rat-heart mitochondrial membranes: induction of permeability transition and cytochrome c release.
FEBS letters 2006;580(27):6311-6.
2006: Giuseppe Petrosillo; Nicola Di Venosa; Marilva Pistolese; Giacoma Casanova; edy tiravanti; Giuseppe Colantuono; Antonio Federici; Giuseppe Paradies; Francesca M Ruggiero
Protective effect of melatonin against mitochondrial dysfunction associated with cardiac ischemia- reperfusion: role of cardiolipin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(2):269-76.
2005: Giuseppe Petrosillo; Nicola Di Venosa; Francesca M Ruggiero; Marilva Pistolese; Donato D'Agostino; edy tiravanti; Tommaso Fiore; Giuseppe Paradies
Mitochondrial dysfunction associated with cardiac ischemia/reperfusion can be attenuated by oxygen tension control. Role of oxygen-free radicals and cardiolipin.
Biochimica et biophysica acta 2005;1710(2-3):78-86.
2004: Giuseppe Petrosillo; Francesca M Ruggiero; Marilva Pistolese; Giuseppe Paradies
Ca2+-induced reactive oxygen species production promotes cytochrome c release from rat liver mitochondria via mitochondrial permeability transition (MPT)-dependent and MPT-independent mechanisms: role of cardiolipin.
The Journal of biological chemistry 2004;279(51):53103-8.
2004: Giuseppe Paradies; Giuseppe Petrosillo; Marilva Pistolese; Nicola Di Venosa; Antonio Federici; Francesca M Ruggiero
Decrease in mitochondrial complex I activity in ischemic/reperfused rat heart: involvement of reactive oxygen species and cardiolipin.
Circulation research 2004;94(1):53-9.
2003: Giuseppe Petrosillo; Francesca M Ruggiero; Giuseppe Paradies
Role of reactive oxygen species and cardiolipin in the release of cytochrome c from mitochondria.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(15):2202-8.
2003: Giuseppe Petrosillo; Francesca M Ruggiero; Nicola Di Venosa; Giuseppe Paradies
Decreased complex III activity in mitochondria isolated from rat heart subjected to ischemia and reperfusion: role of reactive oxygen species and cardiolipin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):714-6.
2002: Giuseppe Paradies; Giuseppe Petrosillo; Marilva Pistolese; Francesca M Ruggiero
Reactive oxygen species affect mitochondrial electron transport complex I activity through oxidative cardiolipin damage.
Gene 2002;286(1):135-41.
2001: Giuseppe Petrosillo; Francesca M Ruggiero; Marilva Pistolese; Giuseppe Paradies
Reactive oxygen species generated from the mitochondrial electron transport chain induce cytochrome c dissociation from beef-heart submitochondrial particles via cardiolipin peroxidation. Possible role in the apoptosis.
FEBS letters 2001;509(3):435-8.
2001: Giuseppe Paradies; Giuseppe Petrosillo; Marilva Pistolese; Francesca M Ruggiero
Reactive oxygen species generated by the mitochondrial respiratory chain affect the complex III activity via cardiolipin peroxidation in beef-heart submitochondrial particles.
Mitochondrion 2001;1(2):151-9.
2000: Giuseppe Paradies; Giuseppe Petrosillo; Marilva Pistolese; Francesca M Ruggiero
The effect of reactive oxygen species generated from the mitochondrial electron transport chain on the cytochrome c oxidase activity and on the cardiolipin content in bovine heart submitochondrial particles.
FEBS letters 2000;466(2-3):323-6.
1999: Giuseppe Paradies; Giuseppe Petrosillo; Maria Nicola Gadaleta; Francesca M Ruggiero
The effect of aging and acetyl-L-carnitine on the pyruvate transport and oxidation in rat heart mitochondria.
FEBS letters 1999;454(3):207-9.
1999: Giuseppe Paradies; Giuseppe Petrosillo; Marilva Pistolese; Nicola Di Venosa; D Serena; Francesca M Ruggiero
Lipid peroxidation and alterations to oxidative metabolism in mitochondria isolated from rat heart subjected to ischemia and reperfusion.
Free radical biology & medicine 1999;27(1-2):42-50.
1998: Giuseppe Paradies; Francesca M Ruggiero; Giuseppe Petrosillo; E Quagliariello
Peroxidative damage to cardiac mitochondria: cytochrome oxidase and cardiolipin alterations.
FEBS letters 1998;424(3):155-8.
1997: Giuseppe Paradies; Francesca M Ruggiero; Giuseppe Petrosillo; E Quagliariello
Alterations in carnitine-acylcarnitine translocase activity and in phospholipid composition in heart mitochondria from hypothyroid rats.
Biochimica et biophysica acta 1997;1362(2-3):193-200.
1997: Giuseppe Paradies; Francesca M Ruggiero; Giuseppe Petrosillo; E Quagliariello
Age-dependent decline in the cytochrome c oxidase activity in rat heart mitochondria: role of cardiolipin.
FEBS letters 1997;406(1-2):136-8.
1997: Giuseppe Paradies; Giuseppe Petrosillo; Francesca M Ruggiero
Cardiolipin-dependent decrease of cytochrome c oxidase activity in heart mitochondria from hypothyroid rats.
Biochimica et biophysica acta 1997;1319(1):5-8.
1996: Giuseppe Paradies; Francesca M Ruggiero; Giuseppe Petrosillo; E Quagliariello
Stimulation of carnitine acylcarnitine translocase activity in heart mitochondria from hyperthyroid rats.
FEBS letters 1996;397(2-3):260-2.
1996: Giuseppe Paradies; Francesca M Ruggiero; Giuseppe Petrosillo; E Quagliariello
Age-dependent impairment of mitochondrial function in rat heart tissue. Effect of pharmacological agents.
Annals of the New York Academy of Sciences 1996;786():252-63.
1995: Giuseppe Paradies; Francesca M Ruggiero; Giuseppe Petrosillo; Maria Nicola Gadaleta; E Quagliariello
Carnitine-acylcarnitine translocase activity in cardiac mitochondria from aged rats: the effect of acetyl-L-carnitine.
Mechanisms of ageing and development 1995;84(2):103-12.
1994: Giuseppe Paradies; Francesca M Ruggiero; Giuseppe Petrosillo; Maria Nicola Gadaleta; E Quagliariello
Effect of aging and acetyl-L-carnitine on the activity of cytochrome oxidase and adenine nucleotide translocase in rat heart mitochondria.
FEBS letters 1994;350(2-3):213-5.
1994: Giuseppe Paradies; Francesca M Ruggiero; Giuseppe Petrosillo; Maria Nicola Gadaleta; E Quagliariello
The effect of aging and acetyl-L-carnitine on the function and on the lipid composition of rat heart mitochondria.
Annals of the New York Academy of Sciences 1994;717():233-43.
1994: Giuseppe Paradies; Francesca M Ruggiero; Giuseppe Petrosillo; E Quagliariello
Enhanced cytochrome oxidase activity and modification of lipids in heart mitochondria from hyperthyroid rats.
Biochimica et biophysica acta 1994;1225(2):165-70.
1993: Giuseppe Paradies; Francesca M Ruggiero; P Dinoi; Giuseppe Petrosillo; E Quagliariello
Decreased cytochrome oxidase activity and changes in phospholipids in heart mitochondria from hypothyroid rats.
Archives of biochemistry and biophysics 1993;307(1):91-5.
1993: Giuseppe Paradies; Francesca M Ruggiero; Giuseppe Petrosillo; E Quagliariello
Age-dependent decrease in the cytochrome c oxidase activity and changes in phospholipids in rat-heart mitochondria.
Archives of gerontology and geriatrics 1993;16(3):263-72.
1992: Giuseppe Paradies; Francesca M Ruggiero; E Quagliariello
Age-dependent changes in the activity of anion carriers and in the lipid composition in rat heart mitochondria.
Annals of the New York Academy of Sciences 1992;673():160-4.
1992: Francesca M Ruggiero; F Cafagna; V Petruzzella; Maria Nicola Gadaleta; E Quagliariello
Lipid composition in synaptic and nonsynaptic mitochondria from rat brains and effect of aging.
Journal of neurochemistry 1992;59(2):487-91.
1992: Giuseppe Paradies; Francesca M Ruggiero; P Dinoi
Decreased activity of the phosphate carrier and modification of lipids in cardiac mitochondria from senescent rats.
The International journal of biochemistry 1992;24(5):783-7.
1992: V Petruzzella; Loris G Baggetto; F Penin; F Cafagna; Francesca M Ruggiero; Palmiro Cantatore; Maria Nicola Gadaleta
In vivo effect of acetyl-L-carnitine on succinate oxidation, adenine nucleotide pool and lipid composition of synaptic and non-synaptic mitochondria from cerebral hemispheres of senescent rats.
Archives of gerontology and geriatrics 1992;14(2):131-44.
1992: Giuseppe Paradies; Francesca M Ruggiero; Maria Nicola Gadaleta; E Quagliariello
The effect of aging and acetyl-L-carnitine on the activity of the phosphate carrier and on the phospholipid composition in rat heart mitochondria.
Biochimica et biophysica acta 1992;1103(2):324-6.
1991: Giuseppe Paradies; Francesca M Ruggiero; P Dinoi
The influence of hypothyroidism on the transport of phosphate and on the lipid composition in rat-liver mitochondria.
Biochimica et biophysica acta 1991;1070(1):180-6.
1991: Giuseppe Paradies; Francesca M Ruggiero
Effect of aging on the activity of the phosphate carrier and on the lipid composition in rat liver mitochondria.
Archives of biochemistry and biophysics 1991;284(2):332-7.
1990: Francesca M Ruggiero; F Cafagna; E Quagliariello
Exchange of free cholesterol between plasma and erythrocytes from hyperthyroid and hypothyroid rats in vitro.
Lipids 1990;25(9):529-33.
1990: Giuseppe Paradies; Francesca M Ruggiero
Stimulation of phosphate transport in rat-liver mitochondria by thyroid hormones.
Biochimica et biophysica acta 1990;1019(2):133-6.
1990: Francesca M Ruggiero; F Cafagna; Maria Nicola Gadaleta; E Quagliariello
Effect of aging and acetyl-L-carnitine on the lipid composition of rat plasma and erythrocytes.
Biochemical and biophysical research communications 1990;170(2):621-6.
1990: Giuseppe Paradies; Francesca M Ruggiero
Enhanced activity of the tricarboxylate carrier and modification of lipids in hepatic mitochondria from hyperthyroid rats.
Archives of biochemistry and biophysics 1990;278(2):425-30.
1990: Giuseppe Paradies; Francesca M Ruggiero
Age-related changes in the activity of the pyruvate carrier and in the lipid composition in rat-heart mitochondria.
Biochimica et biophysica acta 1990;1016(2):207-12.
1989: Giuseppe Paradies; Francesca M Ruggiero
Decreased activity of the pyruvate translocator and changes in the lipid composition in heart mitochondria from hypothyroid rats.
Archives of biochemistry and biophysics 1989;269(2):595-602.
1989: Francesca M Ruggiero; G V Gnoni; E Quagliariello
Lipid composition of brown adipose tissue mitochondria and microsomes in hyperthyroid rats.
The International journal of biochemistry 1989;21(3):327-32.
1988: F Cafagna; V M Digiorgio; Francesca M Ruggiero
Lipid composition in hepatocyte cultures from hypothyroid rats.
Bollettino della Società italiana di biologia sperimentale 1988;64(12):1077-82.
1988: Giuseppe Paradies; Francesca M Ruggiero
The effect of doxorubicin on the transport of pyruvate in rat-heart mitochondria.
Biochemical and biophysical research communications 1988;156(3):1302-7.
1988: V M Digiorgio; F Cafagna; Francesca M Ruggiero
The effect of thyroid hormones on the lipid composition of rat plasma and erythrocyte membranes.
Bollettino della Società italiana di biologia sperimentale 1988;64(11):979-84.
1988: Giuseppe Paradies; Francesca M Ruggiero
Effect of hyperthyroidism on the transport of pyruvate in rat-heart mitochondria.
Biochimica et biophysica acta 1988;935(1):79-86.
1987: Francesca M Ruggiero; G V Gnoni; E Quagliariello
Effect of hypothyroidism on the lipid composition of rat plasma and erythrocyte membranes.
Lipids 1987;22(3):148-51.
1986: Giuseppe Paradies; Francesca M Ruggiero
Characterization of the alpha-cyanocinnamate binding site in rat heart mitochondria and in submitochondrial particles.
Biochimica et biophysica acta 1986;850(2):249-55.
1984: Francesca M Ruggiero; C Landriscina; G V Gnoni; E Quagliariello
Lipid composition of liver mitochondria and microsomes in hyperthyroid rats.
Lipids 1984;19(3):171-8.
1984: Francesca M Ruggiero; C Landriscina; G V Gnoni; E Quagliariello
Alteration of plasma and erythrocyte membrane lipid components in hyperthyroid rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1984;16(1):37-40.
1983: G V Gnoni; C Landriscina; Francesca M Ruggiero; E Quagliariello
Effect of hyperthyroidism on lipogenesis in brown adipose tissue of young rats.
Biochimica et biophysica acta 1983;751(3):271-9.
1981: Francesca M Ruggiero; Francesco M Megli; C Landriscina
[Comparative study of Lecithin and cephalin exchange between liposomes and mitochondria. Activity measured in the presence and absence of a non-specific carrier protein isolated from rat liver].
Bollettino della Società italiana di biologia sperimentale 1981;57(5):483-9.