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Stefania Ruiu

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Stefania Ruiu; Liliana Spina; Maria Collu; Filippo Cottiglia; Sanjay Kasture; Rosanna Longoni; Alessandro Orrù; Elio Acquas
Withania somnifera prevents acquisition and expression of morphine-elicited conditioned place preference.
Ilaria Manca; Andrea Mastinu; Francesca Olimpieri; Gérard Aimè Pinna; Stefania Ruiu; Monica Sani; Simone Tambaro; Alessandro Volonterio; Matteo Zanda; Mirko Emilio Heiner Bottazzi; Matteo Falzoi; Giovanni Loriga; Paolo Lazzari
Novel pyrazole derivatives as neutral CB₁ antagonists with significant activity towards food intake.
Paolo Lazzari; Andrea Mastinu; Battistina Asproni; Mirko Emilio Heiner Bottazzi; Maria M Curzu; Amedeo Pau; Giansalvo Pinna; Gérard A Pinna; Roberta Reali; Stefania Ruiu; Simone Tambaro; Gabriele Murineddu
Synthesis and pharmacological evaluation of novel 4-alkyl-5-thien-2'-yl pyrazole carboxamides.

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2013: Stefania Ruiu; Liliana Spina; Maria Collu; Filippo Cottiglia; Sanjay Kasture; Rosanna Longoni; Alessandro Orrù; Elio Acquas
Withania somnifera prevents acquisition and expression of morphine-elicited conditioned place preference.
Behavioural pharmacology 2013;24(2):133-43.
2013: Ilaria Manca; Andrea Mastinu; Francesca Olimpieri; Gérard Aimè Pinna; Stefania Ruiu; Monica Sani; Simone Tambaro; Alessandro Volonterio; Matteo Zanda; Mirko Emilio Heiner Bottazzi; Matteo Falzoi; Giovanni Loriga; Paolo Lazzari
Novel pyrazole derivatives as neutral CB₁ antagonists with significant activity towards food intake.
European journal of medicinal chemistry 2013;62():256-69.
2012: Paolo Lazzari; Andrea Mastinu; Battistina Asproni; Mirko Emilio Heiner Bottazzi; Maria M Curzu; Amedeo Pau; Giansalvo Pinna; Gérard A Pinna; Roberta Reali; Stefania Ruiu; Simone Tambaro; Gabriele Murineddu
Synthesis and pharmacological evaluation of novel 4-alkyl-5-thien-2'-yl pyrazole carboxamides.
Central nervous system agents in medicinal chemistry 2012;12(4):254-76.
2012: Stefania Ruiu; Sara Piras; Gianluca Casu; Maria Antonietta Casu; Giorgio Marchese
Effects of controlled-release formulations of atypical antipsychotics on functioning and quality of life of schizophrenic individuals.
Expert opinion on pharmacotherapy 2012;13(11):1631-43.
2012: Gabriele Murineddu; Luca Pani; Amedeo Pau; Gérard A Pinna; Stefania Ruiu; Brian F Thomas; Yanan Zhang; Battistina Asproni; Francesco Deligia; Matteo Falzoi; Paolo Lazzari
Tricyclic Pyrazoles. Part 5. Novel 1,4-Dihydroindeno[1,2-c]pyrazole CB2 Ligands Using Molecular Hybridization Based on Scaffold Hopping.
The open medicinal chemistry journal 2012;6():1-14.
2008: Giorgio Marchese; Angela Sanna; Gianluca Casu; Paola Casti; Gabriele Pinna Spada; Stefania Ruiu; Luca Pani
Delta-9-tetrahydrocannabinol differently affects striatal c-Fos expression following haloperidol or clozapine administration.
European journal of pharmacology 2008;598(1-3):16-20.
2007: Giovanni Loriga; Stefania Ruiu; Ilaria Manca; Gabriele Murineddu; Christian Dessi; Luca Pani; Gérard A Pinna
3-{2-[Bis-(4-fluorophenyl)methoxy]ethyl}-6-substituted-3,6-diazabicyclo[3.1.1]heptanes as novel potent dopamine uptake inhibitors.
Bioorganic & medicinal chemistry 2007;15(11):3748-55.
2006: Gabriele Murineddu; Paolo Lazzari; Stefania Ruiu; Angela Sanna; Giovanni Loriga; Ilaria Manca; Matteo Falzoi; Christian Dessì; Maria M Curzu; Giorgio Chelucci; Luca Pani; Gérard A Pinna
Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide.
Journal of medicinal chemistry 2006;49(25):7502-12.
2005: Simone Tambaro; Raymond Mongeau; Christian Dessi; Luca Pani; Stefania Ruiu
Modulation of ATP-mediated contractions of the rat vas deferens through presynaptic cannabinoid receptors.
European journal of pharmacology 2005;525(1-3):150-3.
2005: Gabriele Murineddu; Stefania Ruiu; Giovanni Loriga; Ilaria Manca; Paolo Lazzari; Roberta Reali; Luca Pani; Lucio Toma; Gérard A Pinna
Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide.
Journal of medicinal chemistry 2005;48(23):7351-62.
2005: Gabriele Murineddu; Stefania Ruiu; Jean-Mario Mussinu; Giovanni Loriga; Giuseppe E Grella; Mauro A M Carai; Paolo Lazzari; Luca Pani; Gérard A Pinna
Tricyclic pyrazoles. Part 2: Synthesis and biological evaluation of novel 4,5-dihydro-1H-benzo[g]indazole-based ligands for cannabinoid receptors.
Bioorganic & medicinal chemistry 2005;13(9):3309-20.
2005: Simone Tambaro; Stefania Ruiu; Christian Dessi; Raymond Mongeau; Giorgio Marchese; Luca Pani
Evaluation of tamsulosin and alfuzosin activity in the rat vas deferens: relevance to ejaculation delays.
The Journal of pharmacology and experimental therapeutics 2005;312(2):710-7.
2004: Paola Casti; Giorgio Marchese; Gianluca Casu; Stefania Ruiu; Luca Pani
Blockade of neurotensin receptors affects differently hypo-locomotion and catalepsy induced by haloperidol in mice.
Neuropharmacology 2004;47(1):128-35.
2004: Pier Luigi Ferrarini; Vincenzo Calderone; Tiziana Cavallini; Clementina Manera; Giuseppe Saccomanni; Luca Pani; Stefania Ruiu; Gian Luigi Gessa
Synthesis and biological evaluation of 1,8-naphthyridin-4(1H)-on-3-carboxamide derivatives as new ligands of cannabinoid receptors.
Bioorganic & medicinal chemistry 2004;12(8):1921-33.
2004: Angela Sanna; Elena Congeddu; Luisella Saba; Anna Porcella; Giorgio Marchese; Stefania Ruiu; Paola Casti; Pierluigi Saba; Luca Pani
The cerebellar GABAA alpha6 subunit is differentially modulated by chronic ethanol exposure in normal (R100R) and mutated (Q100Q) sNP rats.
Brain research 2004;998(2):148-54.
2004: Giorgio Marchese; Francesco Bartholini; Maria Antonietta Casu; Stefania Ruiu; Paola Casti; Elena Congeddu; Simone Tambaro; Luca Pani
Haloperidol versus risperidone on rat "early onset" vacuous chewing.
Behavioural brain research 2004;149(1):9-16.
2004: Giorgio Marchese; Francesco Bartholini; Stefania Ruiu; Paola Casti; Gianluca Casu; Luca Pani
Ritanserin counteracts both rat vacuous chewing movements and nigro-striatal tyrosine hydroxylase-immunostaining alterations induced by haloperidol.
European journal of pharmacology 2004;483(1):65-9.
2003: Giorgio Marchese; Paola Casti; Stefania Ruiu; Pierluigi Saba; Angela Sanna; Gianluca Casu; Luca Pani
Haloperidol, but not clozapine, produces dramatic catalepsy in delta9-THC-treated rats: possible clinical implications.
British journal of pharmacology 2003;140(3):520-6.
2003: Gérard A Pinna; Giorgio Cignarella; Stefania Ruiu; Giovanni Loriga; Gabriele Murineddu; Stefania Villa; Giuseppe E Grella; Gregorio Cossu; Walter Fratta
Synthesis of novel diazatricyclodecanes (DTDs). Effects of structural variation at the C3' allyl end and at the phenyl ring of the cinnamyl chain on mu-receptor affinity and opioid antinociception.
Bioorganic & medicinal chemistry 2003;11(18):4015-26.
2003: Stefania Ruiu; Gérard A Pinna; Giorgio Marchese; Jean-Mario Mussinu; Pierluigi Saba; Simone Tambaro; Paola Casti; Romina Vargiu; Luca Pani
Synthesis and characterization of NESS 0327: a novel putative antagonist of the CB1 cannabinoid receptor.
The Journal of pharmacology and experimental therapeutics 2003;306(1):363-70.
2003: Angela Sanna; Elena Congeddu; Anna Porcella; Luisella Saba; Marco Pistis; Michela Peis; Giorgio Marchese; Stefania Ruiu; Carla Lobina; Dennis Grayson; Gian Luigi Gessa; Luca Pani
Characterization of wild-type (R100R) and mutated (Q100Q) GABAA alpha 6 subunit in Sardinian alcohol non-preferring rats (sNP).
Brain research 2003;967(1-2):98-105.
2003: Jean-Mario Mussinu; Stefania Ruiu; Antonio C Mulè; Amedeo Pau; Mauro A M Carai; Giovanni Loriga; Gabriele Murineddu; Gérard A Pinna
Tricyclic pyrazoles. Part 1: synthesis and biological evaluation of novel 1,4-dihydroindeno[1,2-c]pyrazol-based ligands for CB1and CB2 cannabinoid receptors.
Bioorganic & medicinal chemistry 2003;11(2):251-63.
2003: Maria Antonietta Casu; Anna Porcella; Stefania Ruiu; Pierluigi Saba; Giorgio Marchese; Mauro A M Carai; Roberta Reali; Gian Luigi Gessa; Luca Pani
Differential distribution of functional cannabinoid CB1 receptors in the mouse gastroenteric tract.
European journal of pharmacology 2003;459(1):97-105.
2003: Stefania Ruiu; Giorgio Marchese; Pierluigi Saba; Rosalba Satta; Gian Luigi Gessa; Andrea Vaccari; Luca Pani
In vitro evidence for the presence of [3H]-haloperidol uptake in rat brain.
British journal of pharmacology 2003;138(1):188-92.
2002: Giorgio Marchese; Stefania Ruiu; Paola Casti; Pierluigi Saba; Gian Luigi Gessa; Luca Pani
Effect of the amisulpride isomers on rat prolactinemia.
European journal of pharmacology 2002;448(2-3):263-6.
2002: Giorgio Marchese; Stefania Ruiu; Paola Casti; Francesco Bartholini; Pierluigi Saba; Gian Luigi Gessa; Luca Pani
Carmoxirole is able to reduce amisulpride-induced hyperprolactinemia without affecting its central effect.
European journal of pharmacology 2002;447(1):109-14.
2002: Gérard A Pinna; Giorgio Cignarella; Giovanni Loriga; Gabriele Murineddu; Jean-Mario Mussinu; Stefania Ruiu; Paola Fadda; Walter Fratta
N-3(9)-arylpropenyl-N-9(3)-propionyl-3,9-diazabicyclo[3.3.1]nonanes as mu-opioid receptor agonists. Effects on mu-affinity of arylalkenyl chain modifications.
Bioorganic & medicinal chemistry 2002;10(6):1929-37.
2002: Giorgio Marchese; Francesco Bartholini; Stefania Ruiu; Paola Casti; Pierluigi Saba; Gian Luigi Gessa; Luca Pani
Effect of the amisulpride isomers on rat catalepsy.
European journal of pharmacology 2002;444(1-2):69-74.
2002: Giorgio Marchese; Maria Antonietta Casu; Francesco Bartholini; Stefania Ruiu; Pierluigi Saba; Gian Luigi Gessa; Luca Pani
Sub-chronic treatment with classical but not atypical antipsychotics produces morphological changes in rat nigro-striatal dopaminergic neurons directly related to "early onset" vacuous chewing.
The European journal of neuroscience 2002;15(7):1187-96.
2001: Andrea Vaccari; Stefania Ruiu; Pierluigi Saba; Mauro Fà; Raffaele Cagiano; Addolorata Coluccia; Giampaolo Mereu; Luca Steardo; Maria Tattoli; Luigia Trabace; Vincenzo Cuomo
Prenatal low-level exposure to CO alters postnatal development of hippocampal nitric oxide synthase and haem-oxygenase activities in rats.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2001;4(3):219-22.
2000: Stefania Ruiu; Giorgio Marchese; Pierluigi Saba; Gian Luigi Gessa; Luca Pani
The 5-HT2 antagonist ritanserin blocks dopamine re-uptake in the rat frontal cortex.
Molecular psychiatry 2000;5(6):673-7.
1999: Andrea Vaccari; Pierluigi Saba; Ignazia Mocci; Stefania Ruiu
Lanthanides stimulate [3H]tyramine binding in the rat striatum.
Neuroscience letters 1999;261(1-2):49-52.
1999: Micaela Morelli; Annalisa Pinna; Stefania Ruiu; Maria Del Zompo
Induction of Fos-like-immunoreactivity in the central extended amygdala by antidepressant drugs.
Synapse (New York, N.Y.) 1999;31(1):1-4.
1999: Andrea Vaccari; Pierluigi Saba; Ignazia Mocci; Stefania Ruiu
Dithiocarbamate pesticides affect glutamate transport in brain synaptic vesicles.
The Journal of pharmacology and experimental therapeutics 1999;288(1):1-5.
1998: Andrea Vaccari; Stefania Ruiu; Ignazia Mocci; Pierluigi Saba
Selected pyrethroid insecticides stimulate glutamate uptake in brain synaptic vesicles.
Neuroreport 1998;9(15):3519-23.
1998: Andrea Vaccari; Luca Ferraro; Pierluigi Saba; Stefania Ruiu; Ignazia Mocci; Tiziana Antonelli; Sergio Tanganelli
Differential mechanisms in the effects of disulfiram and diethyldithiocarbamate intoxication on striatal release and vesicular transport of glutamate.
The Journal of pharmacology and experimental therapeutics 1998;285(3):961-7.
1997: Paola Piccardi; Giovanni Severino; Alberto Bocchetta; MA Palmas; Stefania Ruiu; Maria Del Zompo
No evidence of association between dopamine D3 receptor gene and bipolar affective disorder.
American journal of medical genetics 1997;74(2):137-9.
1997: Andrea Vaccari; Pierluigi Saba; Ignazia Mocci; Stefania Ruiu
Is increased neurotoxicity a burden of the ageing brain?
Advances in experimental medicine and biology 1997;429():221-34.
1996: Andrea Vaccari; Pierluigi Saba; Stefania Ruiu; Maria Collu; P Devoto
Disulfiram and diethyldithiocarbamate intoxication affects the storage and release of striatal dopamine.
Toxicology and applied pharmacology 1996;139(1):102-8.
1996: Stefania Ruiu; Paola Piccardi; Alberto Bocchetta; Maria Del Zompo
Heterogeneity of monoaminergic vesicular carriers: pharmacological evidence using MPP+ as a marker.
Life sciences 1996;59(20):1703-10.
1993: Maria Del Zompo; Paola Piccardi; Stefania Ruiu; MARINA QUARTU; Gian Luigi Gessa; Andrea Vaccari
Selective MPP+ uptake into synaptic dopamine vesicles: possible involvement in MPTP neurotoxicity.
British journal of pharmacology 1993;109(2):411-4.
1992: Maria Del Zompo; Paola Piccardi; Stefania Ruiu; Giovanni U Corsini; Andrea Vaccari
Characterization of a putatively vesicular binding site for [3H]MPP+ in mouse striatal membranes.
Brain research 1992;571(2):354-7.
1992: Maria Del Zompo; Paola Piccardi; Stefania Ruiu; A Albanese; Micaela Morelli
Localization of MPP+ binding sites in the brain of various mammalian species.
Journal of neural transmission. Parkinson's disease and dementia section 1992;4(3):181-90.
1991: Maria Del Zompo; Paola Piccardi; Stefania Ruiu; Giovanni U Corsini; Andrea Vaccari
High-affinity binding of [3H]1-methyl-4-phenyl-2,3-dihydropyridinium ion to mouse striatal membranes: putative vesicular location.
European journal of pharmacology 1991;202(2):293-4.
1990: Maria Del Zompo; Stefania Ruiu; Roberto Maggio; Paola Piccardi; Giovanni U Corsini
[3H]1-methyl-4-phenyl-2,3-dihydropyridinium ion binding sites in mouse brain: pharmacological and biological characterization.
Journal of neurochemistry 1990;54(6):1905-10.
1989: Stefania Ruiu; Paola Piccardi; Giovanni U Corsini; Maria Del Zompo
Correspondence between 3H-MPP+ binding site and MAO-A enzyme: pharmacological evidences.
Pharmacological research : the official journal of the Italian Pharmacological Society 1989;21 Suppl 1():15-6.