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Bernd Binder

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Nikolina Papac-Milicevic; Tatiana Plyushch; Lubos Ryban; Marianne Steiner; Pavel Uhrin; Gabriel A Wagner; Jan Zaujec; Christoph J Binder; Johannes M Breuss; Muris Cabaravdic; Paul Dremsek; Sabine Fenzl; Christopher K Glass; Bernd R Binder
The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors.
Revu Ann Alexander; Bernd R Binder; Michael Freissmuth; Judit Mihaly-Bison; Gerald Prager; Gerhard J Schütz; Stefan Sunzenauer; Pavel Uhrin; Johannes M Breuss
VEGF-induced endothelial cell migration requires urokinase receptor (uPAR)-dependent integrin redistribution.
Nishamol Geetha; Judit Mihaly; Alexander Stockenhuber; Pavel Uhrin; Bernd R Binder; Francesco Blasi; Michael Freissmuth; Johannes M Breuss
Signal integration and coincidence detection in the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) cascade: concomitant activation of receptor tyrosine kinases and of LRP-1 leads to sustained ERK phosphorylation via down-regulation of dual specificity phosphatases (DUSP1 and -6).

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2012: Nikolina Papac-Milicevic; Tatiana Plyushch; Lubos Ryban; Marianne Steiner; Pavel Uhrin; Gabriel A Wagner; Jan Zaujec; Christoph J Binder; Johannes M Breuss; Muris Cabaravdic; Paul Dremsek; Sabine Fenzl; Christopher K Glass; Bernd R Binder
The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors.
Circulation research 2012;110(8):e50-63.
2012: Revu Ann Alexander; Bernd R Binder; Michael Freissmuth; Judit Mihaly-Bison; Gerald Prager; Gerhard J Schütz; Stefan Sunzenauer; Pavel Uhrin; Johannes M Breuss
VEGF-induced endothelial cell migration requires urokinase receptor (uPAR)-dependent integrin redistribution.
Cardiovascular research 2012;94(1):125-35.
2011: Nishamol Geetha; Judit Mihaly; Alexander Stockenhuber; Pavel Uhrin; Bernd R Binder; Francesco Blasi; Michael Freissmuth; Johannes M Breuss
Signal integration and coincidence detection in the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) cascade: concomitant activation of receptor tyrosine kinases and of LRP-1 leads to sustained ERK phosphorylation via down-regulation of dual specificity phosphatases (DUSP1 and -6).
The Journal of biological chemistry 2011;286(29):25663-74.
2011: Francisco J Monje; Bernd R Binder; Maureen Cabatic; Isabella Divisch; Kurt Herkner; Eun-Jung Kim; Daniela D Pollak
Constant darkness induces IL-6-dependent depression-like behavior through the NF-κB signaling pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(25):9075-83.
2011: Patrick M Brunner; Patricia C Heier; Judit Mihaly-Bison; Ute Priglinger; Bernd R Binder; Gerald W Prager
Density enhanced phosphatase-1 down-regulates urokinase receptor surface expression in confluent endothelial cells.
Blood 2011;117(15):4154-61.
2011: Vladimir Leksa; Robert Loewe; Brigitte Binder; Herbert B Schiller; Paul Eckerstorfer; Florian Forster; Ana Soler-Cardona; Gabriela Ondrovicová; Eva Kutejová; Eva Steinhuber; Johannes Breuss; Johannes Drach; peter petzelbauer; Bernd R Binder; Hannes Stockinger
Soluble M6P/IGF2R released by TACE controls angiogenesis via blocking plasminogen activation.
Circulation research 2011;108(6):676-85.
2011: Taras Afonyushkin; Olga Oskolkova; Bernd R Binder; Valery N Bochkov
Involvement of CK2 in activation of electrophilic genes in endothelial cells by oxidized phospholipids.
Journal of lipid research 2011;52(1):98-103.
2010: Olga Oskolkova; Taras Afonyushkin; Beatrix Preinerstorfer; Wolfgang Bicker; Elena von Schlieffen; Eva Hainzl; Svitlana Demyanets; Gernot Schabbauer; Wolfgang Lindner; Alexandros D Tselepis; Johann Wojta; Bernd R Binder; Valery N Bochkov
Oxidized phospholipids are more potent antagonists of lipopolysaccharide than inducers of inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(12):7706-12.
2010: Philipp Günzl; Kathrin Bauer; Eva Hainzl; Ulrich Matt; Barbara Dillinger; Benedikt Mahr; Sylvia Knapp; Bernd R Binder; Gernot Schabbauer
Anti-inflammatory properties of the PI3K pathway are mediated by IL-10/DUSP regulation.
Journal of leukocyte biology 2010;88(6):1259-69.
2010: Andrea V Schwaiberger; Elke H Heiss; Muris Cabaravdic; Tina Oberan; Jan Zaujec; Daniel Schachner; Pavel Uhrin; Atanas G Atanasov; Johannes M Breuss; Bernd R Binder; Verena M Dirsch
Indirubin-3'-monoxime blocks vascular smooth muscle cell proliferation by inhibition of signal transducer and activator of transcription 3 signaling and reduces neointima formation in vivo.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(12):2475-81.
2010: Gerald Stübiger; Omar Belgacem; Pavel Rehulka; Wolfgang Bicker; Bernd R Binder; Valery Bochkov
Analysis of oxidized phospholipids by MALDI mass spectrometry using 6-aza-2-thiothymine together with matrix additives and disposable target surfaces.
Analytical chemistry 2010;82(13):5502-10.
2010: Gernot Schabbauer; Ulrich Matt; Philipp Günzl; Joanna Warszawska; Tanja Furtner; Eva Hainzl; Immanuel Elbau; Ildiko Mesteri; Bianca Doninger; Bernd R Binder; Sylvia Knapp
Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(1):468-76.
2010: Lukas Orel; Hannah Neumeier; Karin Hochrainer; Bernd R Binder; Johannes A Schmid
Crosstalk between the NF-kappaB activating IKK-complex and the CSN signalosome.
Journal of cellular and molecular medicine 2010;14(6B):1555-68.
2010: Pavel Uhrin; Jan Zaujec; Johannes M Breuss; Damla Olcaydu; Peter Chrenek; Hannes Stockinger; Elke Fuertbauer; Markus Moser; Paula Haiko; Reinhard Fässler; Kari Alitalo; Bernd R Binder; Dontscho Kerjaschki
Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation.
Blood 2010;115(19):3997-4005.
2010: Taras Afonyushkin; Olga V Oskolkova; Maria Philippova; Therese J Resink; Paul Erne; Bernd R Binder; Valery N Bochkov
Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(5):1007-13.
2010: Gerald W Prager; Eva-Maria Lackner; Maria-Theresa Krauth; Matthias Unseld; Marina Poettler; Sylvia Laffer; Sabine Cerny-Reiterer; Wolfgang Lamm; Gabriela V Kornek; Bernd R Binder; Christoph C Zielinski; Peter Valent
Targeting of VEGF-dependent transendothelial migration of cancer cells by bevacizumab.
Molecular oncology 2010;4(2):150-60.
2009: Elena von Schlieffen; Olga V Oskolkova; Gernot Schabbauer; Florian Gruber; Stephan Blüml; Melinda Genest; Alexandra Kadl; Claudia Marsik; Sylvia Knapp; Jesse Chow; Norbert Leitinger; Bernd R Binder; Valery N Bochkov
Multi-hit inhibition of circulating and cell-associated components of the toll-like receptor 4 pathway by oxidized phospholipids.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(3):356-62.
2009: Gerald Prager; Judit Mihaly; Patrick M Brunner; Yuri Koshelnick; Gunilla Hoyer-Hansen; Bernd R Binder
Urokinase mediates endothelial cell survival via induction of the X-linked inhibitor of apoptosis protein.
Blood 2009;113(6):1383-90.
2009: Herbert B Schiller; Andreas Szekeres; Bernd R Binder; Hannes Stockinger; Vladimir Leksa
Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor.
Molecular biology of the cell 2009;20(3):745-56.
2009: Edris A F Mahtab; Rebecca Vicente-Steijn; Nathan D Hahurij; Monique R M Jongbloed; Lambertus J Wisse; Marco C DeRuiter; Pavel Uhrin; Jan Zaujec; Bernd R Binder; Martin J Schalij; Robert E Poelmann; Adriana C Gittenberger-De Groot
Podoplanin deficient mice show a RhoA-related hypoplasia of the sinus venosus myocardium including the sinoatrial node.
Developmental dynamics : an official publication of the American Association of Anatomists 2009;238(1):183-93.
2009: Yvonne L Douglas; Edris A F Mahtab; Monique R M Jongbloed; Pavel Uhrin; Jan Zaujec; Bernd R Binder; Martin J Schalij; Robert E Poelmann; Marco C DeRuiter; Adriana C Gittenberger-De Groot
Pulmonary vein, dorsal atrial wall and atrial septum abnormalities in podoplanin knockout mice with disturbed posterior heart field contribution.
Pediatric research 2009;65(1):27-32.
2008: Olga Oskolkova; Taras Afonyushkin; Alexander Leitner; Elena von Schlieffen; Peter S Gargalovic; Aldons J Lusis; Bernd R Binder; Valery N Bochkov
ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response.
Blood 2008;112(2):330-9.
2008: Karin Hochrainer; Renate Kroismayr; U Baranyi; Bernd R Binder; Joachim Lipp
Highly homologous HERC proteins localize to endosomes and exhibit specific interactions with hPLIC and Nm23B.
Cellular and molecular life sciences : CMLS 2008;65(13):2105-17.
2008: Bernd R Binder; Judit Mihaly
The plasminogen activator inhibitor "paradox" in cancer.
Immunology letters 2008;118(2):116-24.
2008: C Wiesner; Gabriele Winsauer; Ulrike Resch; Martina Hoeth; Johannes A Schmid; J van Hengel; Frans van Roy; Bernd R Binder; Rainer de Martin
Alpha-catulin, a Rho signalling component, can regulate NF-kappaB through binding to IKK-beta, and confers resistance to apoptosis.
Oncogene 2008;27(15):2159-69.
2008: Edris A F Mahtab; Maurits C E F Wijffels; Nynke van den Akker; Nathan D Hahurij; Heleen Lie-Venema; Lambertus J Wisse; Marco C DeRuiter; Pavel Uhrin; Jan Zaujec; Bernd R Binder; Martin J Schalij; Robert E Poelmann; Adriana C Gittenberger-De Groot
Cardiac malformations and myocardial abnormalities in podoplanin knockout mouse embryos: Correlation with abnormal epicardial development.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(3):847-57.
2007: Pavel Uhrin; Christian Schöfer; Jan Zaujec; Lubos Ryban; Mario Hilpert; Klara Weipoltshammer; Ingrid Jerabek; Irene Pirtzkall; Margareta Furtmüller; Mieke Dewerchin; Bernd R Binder; Margarethe Geiger
Male fertility and protein C inhibitor/plasminogen activator inhibitor-3 (PCI): localization of PCI in mouse testis and failure of single plasminogen activator knockout to restore spermatogenesis in PCI-deficient mice.
Fertility and sterility 2007;88(4 Suppl):1049-57.
2007: Florian Gruber; Olga Oskolkova; Alexander Leitner; Michael Mildner; Veronika Mlitz; Barbara Lengauer; Alexandra Kadl; Paul Mrass; Gerhard Krönke; Bernd R Binder; Valery N Bochkov; Norbert Leitinger; Erwin Tschachler
Photooxidation generates biologically active phospholipids that induce heme oxygenase-1 in skin cells.
The Journal of biological chemistry 2007;282(23):16934-41.
2007: Gernot Schabbauer; Bernhard Schweighofer; Diana Mechtcheriakova; Markus Lucerna; Bernd R Binder; Erhard Hofer
Nuclear factor of activated T cells and early growth response-1 cooperate to mediate tissue factor gene induction by vascular endothelial growth factor in endothelial cells.
Thrombosis and haemostasis 2007;97(6):988-97.
2007: Gerhard Krönke; Alexandra Kadl; Elena Ikonomu; Stefan Blüml; Alexander Fürnkranz; Ian J Sarembock; Valery N Bochkov; Markus Exner; Bernd R Binder; Norbert Leitinger
Expression of heme oxygenase-1 in human vascular cells is regulated by peroxisome proliferator-activated receptors.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(6):1276-82.
2007: Julia Malleier; Olga Oskolkova; Valery N Bochkov; Ingrid Jerabek; Barbora Sokolikova; Thomas Perkmann; Johannes M Breuss; Bernd R Binder; Margarethe Geiger
Regulation of protein C inhibitor (PCI) activity by specific oxidized and negatively charged phospholipids.
Blood 2007;109(11):4769-76.
2007: Peter Chrenek; Lubos Ryban; Helga Vetr; Alexander V Makarevich; Pavel Uhrin; Rekha K Paleyanda; Bernd R Binder
Expression of recombinant human factor VIII in milk of several generations of transgenic rabbits.
Transgenic research 2007;16(3):353-61.
2007: Bernd R Binder; Judit Mihaly; Gerald Prager
uPAR-uPA-PAI-1 interactions and signaling: a vascular biologist's view.
Thrombosis and haemostasis 2007;97(3):336-42.
2007: Bernd R Binder
Signaling in endothelial cells: 10 years Department of Vascular Biology and Thrombosis Research at the Medical University Vienna.
Thrombosis and haemostasis 2007;97(3):334-5.
2007: Aurélie S Leroyer; Hirotaka Isobe; Guy Lesèche; Yves Castier; Michel Wassef; Ziad Mallat; Bernd R Binder; Alain Tedgui; Chantal M Boulanger
Cellular origins and thrombogenic activity of microparticles isolated from human atherosclerotic plaques.
Journal of the American College of Cardiology 2007;49(7):772-7.
2007: Bernd R Binder
A novel application for murine double minute 2 antagonists: the p53 tumor suppressor network also controls angiogenesis.
Circulation research 2007;100(1):13-4.
2006: Valery N Bochkov; Maria Philippova; Olga Oskolkova; Alexandra Kadl; Alexander Furnkranz; Erduan Karabeg; Taras Afonyushkin; Florian Gruber; Johannes M Breuss; Alexander Minchenko; Diana Mechtcheriakova; Philipp J Hohensinner; Kathrin Rychli; Johann Wojta; Therese J Resink; Paul Erne; Bernd R Binder; Norbert Leitinger
Oxidized phospholipids stimulate angiogenesis via autocrine mechanisms, implicating a novel role for lipid oxidation in the evolution of atherosclerotic lesions.
Circulation research 2006;99(8):900-8.
2006: Bernd R Binder
Thrombin is bad, accepted; but is smoking good to prevent restenosis?
Journal of thrombosis and haemostasis : JTH 2006;4(10):2188-90.
2006: Gregor Hron; Marietta Kollars; Bernd R Binder; Sabine Eichinger; Paul A Kyrle
Identification of patients at low risk for recurrent venous thromboembolism by measuring thrombin generation.
JAMA : the journal of the American Medical Association 2006;296(4):397-402.
2006: Markus Lucerna; Jirí Pomyje; Diana Mechtcheriakova; Alexandra Kadl; Florian Gruber; Martin Bilban; Yuri Sobanov; Gernot Schabbauer; Johannes M Breuss; Oswald Wagner; Markus Bischoff; Matthias Clauss; Bernd R Binder; Erhard Hofer
Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growth.
Cancer research 2006;66(13):6708-13.
2006: Joakim Huber; Alexander Fürnkranz; Valery N Bochkov; Mary Kim Patricia; Hans Lee; Catherine C Hedrick; Judith A Berliner; Bernd R Binder; Norbert Leitinger
Specific monocyte adhesion to endothelial cells induced by oxidized phospholipids involves activation of cPLA2 and lipoxygenase.
Journal of lipid research 2006;47(5):1054-62.
2005: Vladimír Leksa; Samuel Godar; Herbert B Schiller; Elke Fuertbauer; Arshad Muhammad; Katarina Slezakova; Vaclav Horejsi; Peter Steinlein; Ulrich H Weidle; Bernd R Binder; Hannes Stockinger
TGF-beta-induced apoptosis in endothelial cells mediated by M6P/IGFII-R and mini-plasminogen.
Journal of cell science 2005;118(Pt 19):4577-86.
2005: Stefan Blüml; Stefanie Kirchberger; Valery N Bochkov; Gerhard Krönke; Karl M Stuhlmeier; Otto Majdic; Gerhard J Zlabinger; Walter Knapp; Bernd R Binder; Johannes Stöckl; Norbert Leitinger
Oxidized phospholipids negatively regulate dendritic cell maturation induced by TLRs and CD40.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(1):501-8.
2005: Alexander Furnkranz; Andreas Schober; Valery N Bochkov; Pavel Bashtrykov; Gerhard Kronke; Alexandra Kadl; Bernd R Binder; Christian Weber; Norbert Leitinger
Oxidized phospholipids trigger atherogenic inflammation in murine arteries.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(3):633-8.
2005: Günter Christ; Mariam Nikfardjam; Renate Huber-Beckmann; Michael Gottsauner-Wolf; Dietmar Glogar; Bernd R Binder; Johann Wojta; Kurt Huber
Predictive value of plasma plasminogen activator inhibitor-1 for coronary restenosis: dependence on stent implantation and antithrombotic medication.
Journal of thrombosis and haemostasis : JTH 2005;3(2):233-9.
2005: Tiina T Tuomisto; Bernd R Binder; Seppo Ylä-Herttuala
Genetics, genomics and proteomics in atherosclerosis research.
Annals of medicine 2005;37(5):323-32.
2004: Mitsuhiro Uchiba; Kenji Okajima; Christoph Kaun; Johann Wojta; Bernd R Binder
Inhibition of the endothelial cell activation by antithrombin in vitro.
Thrombosis and haemostasis 2004;92(6):1420-7.
2004: Renate Hofer-Warbinek; Johannes A Schmid; Herbert Mayer; Gabriele Winsauer; L Orel; B Mueller; Ch Wiesner; Bernd R Binder; Rainer de Martin
A highly conserved proapoptotic gene, IKIP, located next to the APAF1 gene locus, is regulated by p53.
Cell death and differentiation 2004;11(12):1317-25.
2004: Renate Kroismayr; Ulrike Baranyi; Christian Stehlik; Andrea Dorfleutner; Bernd R Binder; Joachim Lipp
HERC5, a HECT E3 ubiquitin ligase tightly regulated in LPS activated endothelial cells.
Journal of cell science 2004;117(Pt 20):4749-56.
2004: Christian Stehlik; Renate Kroismayr; Andrea Dorfleutner; Bernd R Binder; Joachim Lipp
VIGR--a novel inducible adhesion family G-protein coupled receptor in endothelial cells.
FEBS letters 2004;569(1-3):149-55.
2004: Herbert Mayer; Martin Bilban; Vladislav Kurtev; Florian Gruber; Oswald Wagner; Bernd R Binder; Rainer de Martin
Deciphering regulatory patterns of inflammatory gene expression from interleukin-1-stimulated human endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(7):1192-8.
2004: Gerald Prager; Johannes M Breuss; Stefan Steurer; Damla Olcaydu; Judit Mihaly; Patrick M Brunner; Hannes Stockinger; Bernd R Binder
Vascular endothelial growth factor receptor-2-induced initial endothelial cell migration depends on the presence of the urokinase receptor.
Circulation research 2004;94(12):1562-70.
2004: Christoph W Kopp; Thomas Hölzenbein; Sabine Steiner; Rodrig Marculescu; Helga Bergmeister; Daniela Seidinger; Isabella Mosberger; Christoph Kaun; Manfred Cejna; Reinhard Horvat; Johann Wojta; Gerald Maurer; Bernd R Binder; Johannes M Breuss; Rupert C Ecker; Rainer de Martin; Erich Minar
Inhibition of restenosis by tissue factor pathway inhibitor: in vivo and in vitro evidence for suppressed monocyte chemoattraction and reduced gelatinolytic activity.
Blood 2004;103(5):1653-61.
2004: Gerald Prager; Bernd R Binder
Genetic determinants: is there an "atherosclerosis gene"?
Acta medica Austriaca 2004;31(1):1-7.
2004: Gerald Prager; Johannes M Breuss; Stefan Steurer; Judit Mihaly; Bernd R Binder
Vascular endothelial growth factor (VEGF) induces rapid prourokinase (pro-uPA) activation on the surface of endothelial cells.
Blood 2004;103(3):955-62.
2003: Gerhard Krönke; Valery N Bochkov; Joakim Huber; Florian Gruber; Stefan Blüml; Alexander Fürnkranz; Alexandra Kadl; Bernd R Binder; Norbert Leitinger
Oxidized phospholipids induce expression of human heme oxygenase-1 involving activation of cAMP-responsive element-binding protein.
The Journal of biological chemistry 2003;278(51):51006-14.
2003: Wei-Jian Zhang; Peter Hufnagl; Bernd R Binder; Johann Wojta
Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression.
Thrombosis and haemostasis 2003;90(5):904-14.
2003: Michael Krebs; Margarethe Geiger; Kaija Polak; Anja Vales; Leopold Schmetterer; Oswald F Wagner; Werner Waldhäusl; Bernd R Binder; Michael Roden
Increased plasma levels of plasminogen activator inhibitor-1 and soluble vascular cell adhesion molecule after triacylglycerol infusion in man.
Thrombosis and haemostasis 2003;90(3):422-8.
2003: Alexander Niessner; Christoph Kaun; Gerlinde Zorn; Walter S Speidl; Zeynep Türel; Gunna Christiansen; Anna Sofie Pedersen; Svend Birkelund; Susan Simon; Apostolos Georgopoulos; Wolfgang Graninger; Rainer de Martin; Joachim Lipp; Bernd R Binder; Gerald Maurer; Kurt Huber; Johann Wojta
Polymorphic membrane protein (PMP) 20 and PMP 21 of Chlamydia pneumoniae induce proinflammatory mediators in human endothelial cells in vitro by activation of the nuclear factor-kappaB pathway.
The Journal of infectious diseases 2003;188(1):108-13.
2003: Karin Ebner; Alexander Bandion; Bernd R Binder; Rainer de Martin; Johannes A Schmid
GMCSF activates NF-kappaB via direct interaction of the GMCSF receptor with IkappaB kinase beta.
Blood 2003;102(1):192-9.
2003: Florian Gruber; Peter Hufnagl; Renate Hofer-Warbinek; Johannes A Schmid; Johannes M Breuss; Renate Huber-Beckmann; Markus Lucerna; Nikolina Papac; Hanna Harant; Ivan J D Lindley; Rainer de Martin; Bernd R Binder
Direct binding of Nur77/NAK-1 to the plasminogen activator inhibitor 1 (PAI-1) promoter regulates TNF alpha -induced PAI-1 expression.
Blood 2003;101(8):3042-8.
2003: Joakim Huber; Valery N Bochkov; Bernd R Binder; Norbert Leitinger
The isoprostane 8-iso-PGE2 stimulates endothelial cells to bind monocytes via cyclic AMP- and p38 MAP kinase-dependent signaling pathways.
Antioxidants & redox signaling 2003;5(2):163-9.
2003: Mitsuhiro Uchiba; Kenji Okajima; Christoph Kaun; Bernd R Binder; Johann Wojta
Gabexate mesilate, a synthetic anticoagulant, inhibits the expression of endothelial leukocyte adhesion molecules in vitro.
Critical care medicine 2003;31(4):1147-53.
2003: Markus Lucerna; Diana Mechtcheriakova; Alexandra Kadl; Gernot Schabbauer; Romana Schäfer; Florian Gruber; Yuri Koshelnick; Horst-Dietmar Müller; Katja Issbrücker; Matthias Clauss; Bernd R Binder; Erhard Hofer
NAB2, a corepressor of EGR-1, inhibits vascular endothelial growth factor-mediated gene induction and angiogenic responses of endothelial cells.
The Journal of biological chemistry 2003;278(13):11433-40.
2003: Abdolreza Rezaie-Majd; Gerald Prager; Robert A Bucek; Gerit-Holger Schernthaner; Thomas Maca; Hans Georg Kress; Peter Valent; Bernd R Binder; Erich Minar; Mehrdad Baghestanian
Simvastatin reduces the expression of adhesion molecules in circulating monocytes from hypercholesterolemic patients.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(3):397-403.
2002: Karin Macfelda; Thomas Weiss; Christoph Kaun; Johannes M Breuss; Gerlinde Zorn; Ulrich Oberndorfer; Margit Voegele-Kadletz; Renate Huber-Beckmann; Robert Ullrich; Bernd R Binder; Udo M Losert; Gerald Maurer; Richard Pacher; Kurt Huber; Johann Wojta
Plasminogen activator inhibitor 1 expression is regulated by the inflammatory mediators interleukin-1alpha, tumor necrosis factor-alpha, transforming growth factor-beta and oncostatin M in human cardiac myocytes.
Journal of molecular and cellular cardiology 2002;34(12):1681-91.
2002: Vladimír Leksa; Samuel Godár; Marek Cebecauer; Ivan Hilgert; Johannes M Breuss; Ulrich H Weidle; Václav Horejsí; Bernd R Binder; Hannes Stockinger
The N terminus of mannose 6-phosphate/insulin-like growth factor 2 receptor in regulation of fibrinolysis and cell migration.
The Journal of biological chemistry 2002;277(43):40575-82.
2002: Valery N Bochkov; Alexandra Kadl; Joakim Huber; Florian Gruber; Bernd R Binder; Norbert Leitinger
Protective role of phospholipid oxidation products in endotoxin-induced tissue damage.
Nature 2002;419(6902):77-81.
2002: Christoph Wiesner; Martina Hoeth; Bernd R Binder; Rainer de Martin
A functional screening assay for the isolation of transcription factors.
Nucleic acids research 2002;30(16):e80.
2002: Johann Wojta; Christoph Kaun; Gerlinde Zorn; Minoo Ghannadan; Alexander W Hauswirth; Wolfgang R Sperr; Gerhard Fritsch; Dieter Printz; Bernd R Binder; Georg Schatzl; Jörg Zwirner; Gerald Maurer; Kurt Huber; Peter Valent
C5a stimulates production of plasminogen activator inhibitor-1 in human mast cells and basophils.
Blood 2002;100(2):517-23.
2002: Manfred Cejna; Johannes M Breuss; Helga Bergmeister; Rainer de Martin; Zhongying Xu; Mario Grgurin; Udo M Losert; Hanns Plenk; Bernd R Binder; Johannes Lammer
Inhibition of neointimal formation after stent placement with adenovirus-mediated gene transfer of I kappa B alpha in the hypercholesterolemic rabbit model: initial results.
Radiology 2002;223(3):702-8.
2002: Peter Valent; Mehrdad Baghestanian; Hans C Bankl; Christian Sillaber; Wolfgang R Sperr; Johann Wojta; Bernd R Binder; Klaus Lechner
New aspects in thrombosis research: possible role of mast cells as profibrinolytic and antithrombotic cells.
Thrombosis and haemostasis 2002;87(5):786-90.
2002: Thomas Ebel; Klaus Bender; Ursula Böcskör; Bernd R Binder; Joachim Lipp
mp23, a Theileria parva transmembrane protein with homology to the protein disulfide isomerase family.
Molecular and biochemical parasitology 2002;121(2):265-8.
2002: Alexandra Kadl; Joakim Huber; Florian Gruber; Valery N Bochkov; Bernd R Binder; Norbert Leitinger
Analysis of inflammatory gene induction by oxidized phospholipids in vivo by quantitative real-time RT-PCR in comparison with effects of LPS.
Vascular pharmacology 2002;38(4):219-27.
2002: Joakim Huber; Herbert Boechzelt; Barbara Karten; Michael Surboeck; Valery N Bochkov; Bernd R Binder; Wolfgang Sattler; Norbert Leitinger
Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(4):581-6.
2002: Bernd R Binder; Günter Christ; Florian Gruber; Nelly Grubic; Peter Hufnagl; Michael Krebs; Judit Mihaly; Gerald Prager
Plasminogen activator inhibitor 1: physiological and pathophysiological roles.
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 2002;17():56-61.
2002: Christoph Merlo; Walter A Wuillemin; Maurice Redondo; Miha Furlan; Irmela Sulzer; Johanna A Kremer-Hovinga; Bernd R Binder; Bernhard Lämmle
Elevated levels of plasma prekallikrein, high molecular weight kininogen and factor XI in coronary heart disease.
Atherosclerosis 2002;161(2):261-7.
2002: Andreas Birbach; Peter Gold; Bernd R Binder; Erhard Hofer; Rainer de Martin; Johannes A Schmid
Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus.
The Journal of biological chemistry 2002;277(13):10842-51.
2002: Johannes M Breuss; Manfred Cejna; Helga Bergmeister; Alexandra Kadl; G Baumgartl; Stefan Steurer; Z Xu; Yuri Koshelnick; Joachim Lipp; Rainer de Martin; Udo M Losert; Johannes Lammer; Bernd R Binder
Activation of nuclear factor-kappa B significantly contributes to lumen loss in a rabbit iliac artery balloon angioplasty model.
Circulation 2002;105(5):633-8.
2002: Joakim Huber; Anja Vales; Goran Mitulovic; Michael Blumer; Rainer Schmid; Joseph L Witztum; Bernd R Binder; Norbert Leitinger
Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(1):101-7.
2002: Valery N Bochkov; Diana Mechtcheriakova; Markus Lucerna; Joakim Huber; Roland Malli; Wolfgang F. Graier; Erhard Hofer; Bernd R Binder; Norbert Leitinger
Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.
Blood 2002;99(1):199-206.
2001: Ingrid Jerabek; Margareta Zechmeister-Machhart; Bernd R Binder; Margarethe Geiger
Binding of retinoic acid by the inhibitory serpin protein C inhibitor.
European journal of biochemistry / FEBS 2001;268(22):5989-96.
2001: Susanne Vrtala; Kora Hirtenlehner; Markus Susani; Mübeccel Akdis; Fatimah Kussebi; Cezmi A. Akdis; Kurt Blaser; Peter Hufnagl; Bernd R Binder; A Politou; A Pastore; Luca Vangelista; Wolfgang R Sperr; Hans Semper; Peter Valent; Christof Ebner; Dietrich Kraft; Rudolf Valenta
Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen Bet v 1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(11):2045-7.
2001: Günter Christ; Senta Graf; Renate Huber-Beckmann; Gerlinde Zorn; Irene Lang; M Kneussi; Bernd R Binder; Kurt Huber
Impairment of the plasmin activation system in primary pulmonary hypertension: evidence for gender differences.
Thrombosis and haemostasis 2001;86(2):557-62.
2001: Norbert Leitinger; Joakim Huber; C Rizza; Diana Mechtcheriakova; Valery N Bochkov; Yuri Koshelnick; Judith A Berliner; Bernd R Binder
The isoprostane 8-iso-PGF(2alpha) stimulates endothelial cells to bind monocytes: differences from thromboxane-mediated endothelial activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(7):1254-6.
2001: Irina Korschineck; S Ziegler; Johannes M Breuss; I Lang; M Lorenz; Christoph Kaun; P F Ambros; Bernd R Binder
Identification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissue.
The Journal of biological chemistry 2001;276(16):13192-7.
2001: W Oitzinger; Renate Hofer-Warbinek; Johannes A Schmid; Yuri Koshelnick; Bernd R Binder; Rainer de Martin
Adenovirus-mediated expression of a mutant IkappaB kinase 2 inhibits the response of endothelial cells to inflammatory stimuli.
Blood 2001;97(6):1611-7.
2001: Maurice Redondo; V A Carroll; Thomas Mauron; Franziska Demarmels Biasiutti; Bernd R Binder; Bernhard Lämmle; Walter A Wuillemin
Hemostatic and fibrinolytic parameters in survivors of myocardial infarction: a low plasma level of plasmin-alpha2-antiplasmin complex is an independent predictor of coronary re-events.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2001;12(1):17-24.
2001: Q R Ruan; Wei-Jian Zhang; Peter Hufnagl; Christoph Kaun; Bernd R Binder; Johann Wojta
Anisodamine counteracts lipopolysaccharide-induced tissue factor and plasminogen activator inhibitor-1 expression in human endothelial cells: contribution of the NF-kappa b pathway.
Journal of vascular research 2001;38(1):13-9.
2001: Diana Mechtcheriakova; Gernot Schabbauer; Markus Lucerna; Matthias Clauss; Bernd R Binder; Erhard Hofer
Specificity, diversity, and convergence in VEGF and TNF-alpha signaling events leading to tissue factor up-regulation via EGR-1 in endothelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(1):230-242.
2000: Regina E Roller; S Janisch; E Kvas; Wolfgang J Schnedl; Bernd R Binder; Johann Wojta; C Korninger
Smooth muscle cell migration promoting activity of plasma predicts restenosis in patients with peripheral arterial occlusive disease undergoing angioplasty.
Thrombosis and haemostasis 2000;84(6):1113-6.
2000: Pavel Uhrin; Mieke Dewerchin; M Hilpert; Peter Chrenek; Christian Schöfer; Margareta Zechmeister-Machhart; Gerhard Krönke; Anja Vales; P Carmeliet; Bernd R Binder; Margarethe Geiger
Disruption of the protein C inhibitor gene results in impaired spermatogenesis and male infertility.
The Journal of clinical investigation 2000;106(12):1531-9.
2000: Wolfgang R Sperr; Susanne Natter; Mehrdad Baghestanian; Josef Smolen; Klaus Wolff; Bernd R Binder; Martin R Müller; Klaus Lechner; Rudolf Valenta; Peter Valent
Autoantibody reactivity in a case of Schnitzler's syndrome: evidence for a Th1-like response and detection of IgG2 anti-FcepsilonRIalpha antibodies.
International archives of allergy and immunology 2000;122(4):279-86.
2000: Renate Hofer-Warbinek; Johannes A Schmid; Christian Stehlik; Bernd R Binder; Joachim Lipp; Rainer de Martin
Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1.
The Journal of biological chemistry 2000;275(29):22064-8.
2000: Johannes A Schmid; Andreas Birbach; Renate Hofer-Warbinek; M Pengg; U Burner; Paul Georg Furtmüller; Bernd R Binder; Rainer de Martin
Dynamics of NF kappa B and Ikappa Balpha studied with green fluorescent protein (GFP) fusion proteins. Investigation of GFP-p65 binding to DNa by fluorescence resonance energy transfer.
The Journal of biological chemistry 2000;275(22):17035-42.
1999: Gerhard Bavinzski; Bernd Richling; Bernd R Binder; Andreas Gruber; V Talazoglu; Wolfgang Dietrich; I Schwendtenwein; Hanns Plenk
Histopathological findings in experimental aneurysms embolized with conventional and thrombogenic/antithrombolytic Guglielmi coils.
Minimally invasive neurosurgery : MIN 1999;42(4):167-74.
1999: Susanne Seiberler; Susanne Natter; Peter Hufnagl; Bernd R Binder; Rudolf Valenta
Characterization of IgE-reactive autoantigens in atopic dermatitis. 2. A pilot study on IgE versus IgG subclass response and seasonal variation of IgE autoreactivity.
International archives of allergy and immunology 1999;120(2):117-25.
1999: Susanne Seiberler; Agnes Bugajska-Schretter; Peter Hufnagl; Bernd R Binder; Johannes Stöckl; Susanne Spitzauer; Peter Valent; Rudolf Valenta
Characterization of IgE-reactive autoantigens in atopic dermatitis. 1. Subcellular distribution and tissue-specific expression.
International archives of allergy and immunology 1999;120(2):108-16.
1999: Michael Krebs; Christoph Kaun; M Lorenz; M Haag-Weber; Margarethe Geiger; Bernd R Binder
Protease dependent activation of endothelial cells by peritoneal dialysis effluents.
Thrombosis and haemostasis 1999;82(4):1334-41.
1999: Mariam Nikfardjam; Senta Graf; R Beckmann; Stephan Hornykewycz; J Koller-Strametz; Bernd R Binder; Kurt Huber
Fibrinolytic response to venous occlusion compared to physical stress test in young patients with coronary artery disease.
Thrombosis and haemostasis 1999;82 Suppl 1():80-4.
1999: M J Prendes; Edith Bielek; Margareta Zechmeister-Machhart; E Vanyek-Zavadil; VA Carroll; Johannes M Breuss; Bernd R Binder; Margarethe Geiger
Synthesis and ultrastructural localization of protein C inhibitor in human platelets and megakaryocytes.
Blood 1999;94(4):1300-12.
1999: Yuri Koshelnick; M Ehart; Hannes Stockinger; Bernd R Binder
Mechanisms of signaling through urokinase receptor and the cellular response.
Thrombosis and haemostasis 1999;82(2):305-11.
1999: Michael Krebs; Pavel Uhrin; Anja Vales; M J Prendes-Garcia; Johann Wojta; Margarethe Geiger; Bernd R Binder
Protein C inhibitor is expressed in keratinocytes of human skin.
The Journal of investigative dermatology 1999;113(1):32-7.
1999: H Holzmüller; T Moll; Renate Hofer-Warbinek; Diana Mechtcheriakova; Bernd R Binder; Erhard Hofer
A transcriptional repressor of the tissue factor gene in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(7):1804-11.
1999: Günter Christ; Karam Kostner; Manfred Zehetgruber; Bernd R Binder; D Gulba; Kurt Huber
Plasmin activation system in restenosis: role in pathogenesis and clinical prediction?
Journal of thrombosis and thrombolysis 1999;7(3):277-85.
1999: Alenka Mavri; Mojca Stegnar; Michael Krebs; JT Sentocnik; Margarethe Geiger; Bernd R Binder
Impact of adipose tissue on plasma plasminogen activator inhibitor-1 in dieting obese women.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(6):1582-7.
1999: Diana Mechtcheriakova; Alexander Wlachos; H Holzmüller; Bernd R Binder; Erhard Hofer
Vascular endothelial cell growth factor-induced tissue factor expression in endothelial cells is mediated by EGR-1.
Blood 1999;93(11):3811-23.
1999: Thomas Ebel; J Gerhards; Bernd R Binder; Joachim Lipp
Theileria parva 104 kDa microneme--rhoptry protein is membrane-anchored by a non-cleaved amino-terminal signal sequence for entry into the endoplasmic reticulum.
Molecular and biochemical parasitology 1999;100(1):19-26.
1999: Regina E Roller; S Janisch; VA Carroll; E Kvas; Ernst Pilger; Bernd R Binder; Johann Wojta
Changes in the fibrinolytic system in patients with peripheral arterial occlusive disease undergoing percutaneous transluminal angioplasty.
Thrombosis research 1999;94(4):241-7.
1999: Friedrich Wimazal; Wolfgang R Sperr; Hans-Peter Horny; VA Carroll; Bernd R Binder; Christa Fonatsch; S Walchshofer; Manuela Födinger; Ilse Schwarzinger; Puchit Samorapoompichit; Andreas Chott; A M Dvorak; Klaus Lechner; Peter Valent
Hyperfibrinolysis in a case of myelodysplastic syndrome with leukemic spread of mast cells.
American journal of hematology 1999;61(1):66-77.
1999: Michael Gottsauner-Wolf; Heinz Sochor; Stephan Hornykewycz; R Beckmann; Irene Lang; Peter Probst; Bernd R Binder; Kurt Huber
Predictive value of PAI-1 plasma activity and thallium perfusion imaging for restenosis after percutaneous transluminal angioplasty in clinically asymptomatic patients.
Thrombosis and haemostasis 1999;81(4):522-6.
1999: Johann Wojta; Christoph Kaun; Johannes M Breuss; Yuri Koshelnick; R Beckmann; E Hattey; Michael Mildner; Wolfgang Weninger; T Nakamura; Erwin Tschachler; Bernd R Binder
Hepatocyte growth factor increases expression of vascular endothelial growth factor and plasminogen activator inhibitor-1 in human keratinocytes and the vascular endothelial growth factor receptor flk-1 in human endothelial cells.
Laboratory investigation; a journal of technical methods and pathology 1999;79(4):427-38.
1999: Maurice Redondo; H H Watzke; B Stucki; Irmela Sulzer; Franziska Demarmels Biasiutti; Bernd R Binder; Miha Furlan; Bernhard Lämmle; Walter A Wuillemin
Coagulation factors II, V, VII, and X, prothrombin gene 20210G-->A transition, and factor V Leiden in coronary artery disease: high factor V clotting activity is an independent risk factor for myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(4):1020-5.
1999: J C Zhang; Q Ruan; L Paucz; A Fabry; Bernd R Binder; Johann Wojta
Stimulation of tissue factor expression in human microvascular and macrovascular endothelial cells by cultured vascular smooth muscle cells in vitro.
Journal of vascular research 1999;36(2):126-32.
1999: Samuel Godár; Vaclav Horejsi; Ulrich H Weidle; Bernd R Binder; Cornelia Hansmann; Hannes Stockinger
M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1.
European journal of immunology 1999;29(3):1004-13.
1999: Susanne Vrtala; Kora Hirtenlehner; Markus Susani; Peter Hufnagl; Bernd R Binder; Luca Vangelista; A Pastore; Wolfgang R Sperr; Peter Valent; Christof Ebner; Dietrich Kraft; Rudolf Valenta
Genetic engineering of recombinant hypoallergenic oligomers of the major birch pollen allergen, Bet v 1: candidates for specific immunotherapy.
International archives of allergy and immunology 1999;118(2-4):218-9.
1999: Christian Sillaber; Mehrdad Baghestanian; Dorian Bevec; Martin Willheim; Hermine Agis; Stylianos Kapiotis; Wolfgang Füreder; Hans C Bankl; Hans P Kiener; Wolfgang Speiser; Bernd R Binder; Klaus Lechner; Peter Valent
The mast cell as site of tissue-type plasminogen activator expression and fibrinolysis.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):1032-41.
1999: M Geiger; Bernd R Binder
[Pathophysiology of immobilization].
Wiener medizinische Wochenschrift (1946) 1999;149(2-4):33-4.
1999: VA Carroll; Bernd R Binder
The role of the plasminogen activation system in cancer.
Seminars in thrombosis and hemostasis 1999;25(2):183-97.
1998: Peter F Ambros; J Schmid; Silvia Rumpler; Bernd R Binder; Rainer de Martin
Localization of the human I-kappaB kinase-beta (IKBKB) to chromosome 8p11.2 by fluorescence in situ hybridization and radiation hybrid mapping.
Genomics 1998;54(3):575-6.
1998: Susanne Natter; Susanne Seiberler; Peter Hufnagl; Bernd R Binder; Alexander M Hirschl; J Ring; D Abeck; T Schmidt; Peter Valent; Rudolf Valenta
Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(14):1559-69.
1998: Alexander Geppert; Senta Graf; R Beckmann; Stephan Hornykewycz; E Schuster; Bernd R Binder; Kurt Huber
Concentration of endogenous tPA antigen in coronary artery disease: relation to thrombotic events, aspirin treatment, hyperlipidemia, and multivessel disease.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(10):1634-42.
1998: Christian Stehlik; Rainer de Martin; I Kumabashiri; Johannes A Schmid; Bernd R Binder; Joachim Lipp
Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.
The Journal of experimental medicine 1998;188(1):211-6.
1998: Mojca Stegnar; P Uhrin; Polona Peternel; Alenka Mavri; B Salobir-Pajnic; J Stare; Bernd R Binder
The 4G/5G sequence polymorphism in the promoter of plasminogen activator inhibitor-1 (PAI-1) gene: relationship to plasma PAI-1 level in venous thromboembolism.
Thrombosis and haemostasis 1998;79(5):975-9.
1998: Christian Stehlik; Rainer de Martin; Bernd R Binder; Joachim Lipp
Cytokine induced expression of porcine inhibitor of apoptosis protein (iap) family member is regulated by NF-kappa B.
Biochemical and biophysical research communications 1998;243(3):827-32.
1998: Manfred Zehetgruber; Günter Christ; Harald Gabriel; Gerald Mundigler; R Beckmann; Bernd R Binder; Kurt Huber
Effect of antihypertensive treatment with doxazosin on insulin sensitivity and fibrinolytic parameters.
Thrombosis and haemostasis 1998;79(2):378-82.
1998: Elisabeth Gharehbaghi-Schnell; Josef Finsterer; Irina Korschineck; Bruno Mamoli; Bernd R Binder
Myotonic dystrophy: molecular genetics and diagnosis.
Wiener klinische Wochenschrift 1998;110(1):7-14.
1998: Elisabeth Gharehbaghi-Schnell; Josef Finsterer; Irina Korschineck; Bruno Mamoli; Bernd R Binder
Genotype-phenotype correlation in myotonic dystrophy.
Clinical genetics 1998;53(1):20-6.
1998: Peter Valent; Christian Sillaber; Mehrdad Baghestanian; Hans C Bankl; Hans P Kiener; Klaus Lechner; Bernd R Binder
What have mast cells to do with edema formation, the consecutive repair and fibrinolysis?
International archives of allergy and immunology 1998;115(1):2-8.
1997: Yuri Koshelnick; M Ehart; Peter Hufnagl; P C Heinrich; Bernd R Binder
Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598.
The Journal of biological chemistry 1997;272(45):28563-7.
1997: S Ecke; Margarethe Geiger; Bernd R Binder
Heparin binding of protein-C inhibitor--analysis of the effect of heparin on the interaction of protein-C inhibitor with tissue kallikrein.
European journal of biochemistry / FEBS 1997;248(2):475-80.
1997: Wei-Jian Zhang; Johann Wojta; Bernd R Binder
Regulation of the fibrinolytic potential of cultured human umbilical vein endothelial cells: astragaloside IV downregulates plasminogen activator inhibitor-1 and upregulates tissue-type plasminogen activator expression.
Journal of vascular research 1997;34(4):273-80.
1997: Margarethe Geiger; Michael Krebs; Ingrid Jerabek; Bernd R Binder
Protein C inhibitor (PCI) and heparin cofactor II (HCII): possible alternative roles of these heparin-binding serpins outside the hemostatic system.
Immunopharmacology 1997;36(2-3):279-84.
1997: Wei-Jian Zhang; Johann Wojta; Bernd R Binder
Effect of notoginsenoside R1 on the synthesis of components of the fibrinolytic system in cultured smooth muscle cells of human pulmonary artery.
Cellular and molecular biology (Noisy-le-Grand, France) 1997;43(4):581-7.
1997: Günter Christ; Peter Hufnagl; Christoph Kaun; Gerald Mundigler; Günther Laufer; Kurt Huber; Johann Wojta; Bernd R Binder
Antifibrinolytic properties of the vascular wall. Dependence on the history of smooth muscle cell doublings in vitro and in vivo.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(4):723-30.
1997: Christian Sillaber; Mehrdad Baghestanian; R Hofbauer; Irene Virgolini; Hans C Bankl; Wolfgang Füreder; Hermine Agis; Martin Willheim; Maria Leimer; Otto Scheiner; Bernd R Binder; Hans P Kiener; Dorian Bevec; Gerhard Fritsch; Otto Majdic; Hans Georg Kress; H Gadner; Klaus Lechner; Peter Valent
Molecular and functional characterization of the urokinase receptor on human mast cells.
The Journal of biological chemistry 1997;272(12):7824-32.
1997: Wei-Jian Zhang; Johann Wojta; Bernd R Binder
Notoginsenoside R1 counteracts endotoxin-induced activation of endothelial cells in vitro and endotoxin-induced lethality in mice in vivo.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(3):465-74.
1997: Mehrdad Baghestanian; R Hofbauer; Hans Georg Kress; Johann Wojta; A Fabry; Bernd R Binder; Christoph Kaun; Martin R Müller; Mohammad Reza Mehrabi; Stylianos Kapiotis; Gürkan Sengoelge; Minoo Ghannadan; Klaus Lechner; Peter Valent
Thrombin augments vascular cell-dependent migration of human mast cells: role of MGF.
Thrombosis and haemostasis 1997;77(3):577-84.
1997: Margareta Zechmeister-Machhart; Peter Hufnagl; Pavel Uhrin; Irina Korschineck; Bernd R Binder; Margarethe Geiger
Molecular cloning and sequence analysis of the mouse protein C inhibitor gene.
Gene 1997;186(1):61-6.
1997: VA Carroll; M R Griffiths; Margarethe Geiger; C Merlo; M Furlan; B Lämmle; Bernd R Binder
Plasma protein C inhibitor is elevated in survivors of myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(1):114-8.
1996: N Grubic; Mojca Stegnar; Polona Peternel; A Kaider; Bernd R Binder
A novel G/A and the 4G/5G polymorphism within the promoter of the plasminogen activator inhibitor-1 gene in patients with deep vein thrombosis.
Thrombosis research 1996;84(6):431-43.
1996: J C Zhang; A Fabry; L Paucz; Johann Wojta; Bernd R Binder
Human fibroblasts downregulate plasminogen activator inhibitor type-1 in cultured human macrovascular and microvascular endothelial cells.
Blood 1996;88(10):3880-6.
1996: Hans Zoellner; M Höfler; R Beckmann; P Hufnagl; E Vanyek; Edith Bielek; Johann Wojta; A Fabry; S Lockie; Bernd R Binder
Serum albumin is a specific inhibitor of apoptosis in human endothelial cells.
Journal of cell science 1996;109 ( Pt 10)():2571-80.
1996: Manfred Zehetgruber; R Beckmann; H Gabriel; Günter Christ; Bernd R Binder; Kurt Huber
The ACE-inhibitor lisinopril affects plasma insulin levels but not fibrinolytic parameters.
Thrombosis research 1996;83(2):143-52.
1996: X Zheng; Margareta Zechmeister-Machhart; Pavel Uhrin; P Hufnagl; Margarethe Geiger; Bernd R Binder
Effect of protein C inhibitor (PCI) on in vitro fertilization.
Immunopharmacology 1996;33(1-3):140-2.
1996: T Böhm; Margarethe Geiger; Bernd R Binder
Isolation and characterization of tissue-type plasminogen activator- binding proteoglycans from human umbilical vein endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 1996;16(5):665-72.
1996: Margareta Zechmeister-Machhart; P Hufnagl; Pavel Uhrin; J Xu; Margarethe Geiger; Bernd R Binder
Molecular cloning and tissue distribution of mouse protein C inhibitor (PCI).
Immunopharmacology 1996;32(1-3):96-8.
1996: Margarethe Geiger; Margareta Zechmeister-Machhart; Pavel Uhrin; P Hufnagl; S Ecke; U Priglinger; J Xu; X Zheng; Bernd R Binder
Protein C inhibitor (PCI).
Immunopharmacology 1996;32(1-3):53-6.
1995: J C Zhang; Johann Wojta; Bernd R Binder
Growth and fibrinolytic parameters of human umbilical vein endothelial cells seeded onto cardiovascular grafts.
The Journal of thoracic and cardiovascular surgery 1995;109(6):1059-65.
1994: D B al-Azhary; Johann Wojta; Bernd R Binder
Fibrinolytic system of cultured rabbit aortic endothelial cells.
Thrombosis research 1994;75(5):559-68.
1994: X Zheng; Margarethe Geiger; S Ecke; Edith Bielek; Peter Donner; U Eberspächer; Wolf-Dieter Schleuning; Bernd R Binder
Inhibition of acrosin by protein C inhibitor and localization of protein C inhibitor to spermatozoa.
The American journal of physiology 1994;267(2 Pt 1):C466-72.
1994: Wei-Jian Zhang; Johann Wojta; Bernd R Binder
Effect of notoginsenoside R1 on the synthesis of tissue-type plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(7):1040-6.
1994: Johann Wojta; T Nakamura; A Fabry; P Hufnagl; R Beckmann; K McGrath; Bernd R Binder
Hepatocyte growth factor stimulates expression of plasminogen activator inhibitor type 1 and tissue factor in HepG2 cells.
Blood 1994;84(1):151-7.
1994: U Priglinger; Margarethe Geiger; Edith Bielek; E Vanyek; Bernd R Binder
Binding of urinary protein C inhibitor to cultured human epithelial kidney tumor cells (TCL-598). The role of glycosaminoglycans present on the luminal cell surface.
The Journal of biological chemistry 1994;269(20):14705-10.
1993: D Seiffert; J Poenninger; Bernd R Binder
Organization of the gene encoding mouse vitronectin.
Gene 1993;134(2):303-4.
1993: Johann Wojta; Marisa Gallicchio; Hans Zoellner; P Hufnagl; Karena Last; E L Filonzi; Bernd R Binder; John A Hamilton; K McGrath
Thrombin stimulates expression of tissue-type plasminogen activator and plasminogen activator inhibitor type 1 in cultured human vascular smooth muscle cells.
Thrombosis and haemostasis 1993;70(3):469-74.
1993: Kurt Huber; J C Kirchheimer; A Sedlmayer; C Bell; D Ermler; Bernd R Binder
Clinical value of determination of urokinase-type plasminogen activator antigen in plasma for detection of colorectal cancer: comparison with circulating tumor-associated antigens CA 19-9 and carcinoembryonic antigen.
Cancer research 1993;53(8):1788-93.
1993: G Christ; D Seiffert; P Hufnagl; Alois Gessl; Johann Wojta; Bernd R Binder
Type 1 plasminogen activator inhibitor synthesis of endothelial cells is downregulated by smooth muscle cells.
Blood 1993;81(5):1277-83.
1993: Kurt Huber; R Beckmann; Peter Probst; F Rauscha; F Kaindl; Bernd R Binder
Influence of cardiac output on peak t-PA plasma levels in patients receiving thrombolytic therapy with recombinant tissue-type plasminogen activator--correlation with patency rate.
Thrombosis and haemostasis 1993;69(1):45-9.
1992: D Seiffert; Margarethe Geiger; S Ecke; Bernd R Binder
Vitronectin modulates glycosaminoglycan dependent reactions of protein C inhibitor.
Thrombosis and haemostasis 1992;68(6):657-61.
1992: S Ecke; Margarethe Geiger; Bernd R Binder
Glycosaminoglycans regulate the enzyme specificity of protein C inhibitor.
Annals of the New York Academy of Sciences 1992;667():84-6.
1992: K Addo-Boadu; G Christ; Bernd R Binder
Effects of cocultivation of human umbilical vein endothelial cells with Bowes melanoma cells.
Annals of the New York Academy of Sciences 1992;667():186-8.
1992: Alexander Geppert; Bernd R Binder
Allosteric regulation of tPA-mediated plasminogen activation by a modifier mechanism: evidence for a binding site for plasminogen on the tPA A-chain.
Archives of biochemistry and biophysics 1992;297(2):205-12.
1992: Oswald F Wagner; G Christ; Johann Wojta; Heinrich Vierhapper; S Parzer; Peter Nowotny; B Schneider; Werner Waldhäusl; Bernd R Binder
Polar secretion of endothelin-1 by cultured endothelial cells.
The Journal of biological chemistry 1992;267(23):16066-8.
1992: E Petzelbauer; D Seiffert; R Beckmann; B Pusch; Margarethe Geiger; Bernd R Binder
Modulation of heparin cofactor II activity by glycosaminoglycans and adhesive glycoproteins.
Thrombosis research 1992;66(5):559-67.
1992: S Ecke; Margarethe Geiger; I Resch; I Jerabek; L Sting; M Maier; Bernd R Binder
Inhibition of tissue kallikrein by protein C inhibitor. Evidence for identity of protein C inhibitor with the kallikrein binding protein.
The Journal of biological chemistry 1992;267(10):7048-52.
1992: Kurt Huber; J C Kirchheimer; D Ermler; C Bell; Bernd R Binder
Determination of plasma urokinase-type plasminogen activator antigen in patients with primary liver cancer: characterization as tumor-associated antigen and comparison with alpha-fetoprotein.
Cancer research 1992;52(7):1717-20.
1992: Kurt Huber; M Jörg; Peter Probst; E Schuster; Irene Lang; F Kaindl; Bernd R Binder
A decrease in plasminogen activator inhibitor-1 activity after successful percutaneous transluminal coronary angioplasty is associated with a significantly reduced risk for coronary restenosis.
Thrombosis and haemostasis 1992;67(2):209-13.
1992: S Ecke; Margarethe Geiger; I Resch; I Jerabek; M Maier; Bernd R Binder
Possible identity of kallikrein binding protein with protein C inhibitor.
Agents and actions. Supplements 1992;38 ( Pt 1)():182-9.
1992: I Jerabek; Z Stetina; R Furtner; Bernd R Binder; M Maier
Determination of human low molecular weight kininogen by immunoassay.
Agents and actions. Supplements 1992;38 ( Pt 1)():257-66.
1991: Margarethe Geiger; Bernd R Binder
Plasminogen activation in diabetes mellitus: kinetics of plasmin formation with plasminogen and tissue plasminogen activator from diabetic donors.
Seminars in thrombosis and hemostasis 1991;17(4):417-21.
1991: Ulrich Maier; J C Kirchheimer; G Hienert; Günter Christ; Bernd R Binder
Fibrinolytic parameters in spermatozoas and seminal plasma.
The Journal of urology 1991;146(3):906-8.
1991: J C Kirchheimer; Bernd R Binder
Function of receptor-bound urokinase.
Seminars in thrombosis and hemostasis 1991;17(3):246-50.
1991: Margarethe Geiger; U Priglinger; J H Griffin; Bernd R Binder
Urinary protein C inhibitor. Glycosaminoclycans synthesized by the epithelial kidney cell line TCL-598 enhance its interaction with urokinase.
The Journal of biological chemistry 1991;266(18):11851-7.
1991: Kurt Huber; J C Kirchheimer; C Korninger; Bernd R Binder
Hepatic synthesis and clearance of components of the fibrinolytic system in healthy volunteers and in patients with different stages of liver cirrhosis.
Thrombosis research 1991;62(5):491-500.
1991: R Beckmann; Margarethe Geiger; C de Vries; H Pannekoek; Bernd R Binder
Fibronectin decreases the stimulatory effect of fibrin and fibrinogen fragment FCB-2 on plasmin formation by tissue plasminogen activator.
The Journal of biological chemistry 1991;266(4):2227-32.
1990: Alexander Reinthaller; J C Kirchheimer; Josef Deutinger; C Bieglmayer; Günter Christ; Bernd R Binder
Plasminogen activators, plasminogen activator inhibitor, and fibronectin in human granulosa cells and follicular fluid related to oocyte maturation and intrafollicular gonadotropin levels.
Fertility and sterility 1990;54(6):1045-51.
1990: Bernd R Binder
Influence of urokinase on cell proliferation and invasion.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1990;1(6):717-20.
1990: J C Kirchheimer; Bernd R Binder; Heinz G Remold
Matrix-bound plasminogen activator inhibitor type 1 inhibits the invasion of human monocytes into interstitial tissue.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(5):1518-22.
1990: Kurt Huber; I Resch; Thomas Stefenelli; Irene Lang; Peter Probst; F Kaindl; Bernd R Binder
Plasminogen activator inhibitor-1 levels in patients with chronic angina pectoris with or without angiographic evidence of coronary sclerosis.
Thrombosis and haemostasis 1990;63(3):336-9.
1990: M Maier; G Reissert; I Jerabek; I Bergmann; E Balaun; F Lottspeich; Bernd R Binder
Release of [hydroxyproline3]-kinins by tissue kallikreins of pig, rat and man.
Biochemical pharmacology 1990;39(3):549-53.
1990: J C Kirchheimer; Heinz Kölbl; G Tatra; Bernd R Binder
Relationship between plasma levels of components of the fibrinolytic system and acute-phase reactants in patients with uterine malignancies.
European journal of clinical investigation 1990;20(1):79-84.
1989: Kurt Huber; I Resch; D Rosc; Peter Probst; F Kaindl; Bernd R Binder
Heparin induced increase of t-PA antigen plasma levels in patients with unstable angina: no evidence for clinical benefit of heparinization during the initial phase of treatment.
Thrombosis research 1989;55(6):779-84.
1989: Margarethe Geiger; K Huber; Johann Wojta; L Stingl; F Espana; J H Griffin; Bernd R Binder
Complex formation between urokinase and plasma protein C inhibitor in vitro and in vivo.
Blood 1989;74(2):722-8.
1989: Elisabeth Koller; F Koller; Bernd R Binder
Purification and identification of the lipoprotein-binding proteins from human blood platelet membrane.
The Journal of biological chemistry 1989;264(21):12412-8.
1989: J C Kirchheimer; Johann Wojta; Günter Christ; Bernd R Binder
Functional inhibition of endogenously produced urokinase decreases cell proliferation in a human melanoma cell line.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5424-8.
1989: Johann Wojta; R Beckmann; L Turcu; Oswald F Wagner; A J van Zonneveld; Bernd R Binder
Functional characterization of monoclonal antibodies directed against fibrin binding domains of tissue-type plasminogen activator.
The Journal of biological chemistry 1989;264(14):7957-61.
1989: W Muellbacher; M Maier; Bernd R Binder
Regulation of plasminogen activation in isolated perfused rat kidney.
The American journal of physiology 1989;256(5 Pt 2):F787-93.
1989: J C Kirchheimer; Günter Christ; Bernd R Binder
Growth stimulation of human epidermal cells by urokinase is restricted to the intact active enzyme.
European journal of biochemistry / FEBS 1989;181(1):103-7.
1989: M Maier; G Reissert; I Jerabek; Bernd R Binder
Characterization of kinins released from human kininogens by human urinary kallikrein.
Advances in experimental medicine and biology 1989;247A():353-7.
1989: H Malus; Bernd R Binder; M Maier
Kininase activities in the human pituitary gland.
Advances in experimental medicine and biology 1989;247A():293-8.
1988: Kurt Huber; D Rosc; I Resch; E Schuster; Dietmar Glogar; F Kaindl; Bernd R Binder
Circadian fluctuations of plasminogen activator inhibitor and tissue plasminogen activator levels in plasma of patients with unstable coronary artery disease and acute myocardial infarction.
Thrombosis and haemostasis 1988;60(3):372-6.
1988: M Maier; I Jerabek; G Reissert; E Höltzl; Bernd R Binder
Correlation of two different assays for urinary kallikrein in normotensive and hypertensive subjects.
Clinica chimica acta; international journal of clinical chemistry 1988;178(2):127-39.
1988: G Hienert; J C Kirchheimer; H Pflüger; Bernd R Binder
Urokinase-type plasminogen activator as a marker for the formation of distant metastases in prostatic carcinomas.
The Journal of urology 1988;140(6):1466-9.
1988: Kurt Huber; Johann Wojta; J C Kirchheimer; D Ermler; Bernd R Binder
Plasminogen activators and plasminogen activator inhibitor in malignant and non-malignant ascitic fluid.
European journal of clinical investigation 1988;18(6):595-9.
1988: Christoph Baumgartner; Kurt Huber; F Holzner; K Zeiler; Eduard Auff; Bernd R Binder
[Persistent changes in tissue-type plasminogen activator and plasminogen activator inhibitor fibrinolytic parameters in patients following juvenile ischemic cerebral infarct].
Klinische Wochenschrift 1988;66(22):1110-5.
1988: J C Kirchheimer; Johann Wojta; Günter Christ; G Hienert; Bernd R Binder
Mitogenic effect of urokinase on malignant and unaffected adjacent human renal cells.
Carcinogenesis 1988;9(11):2121-3.
1988: Heinz Koelbl; J C Kirchheimer; G Tatra; Günter Christ; Bernd R Binder
Increased plasma levels of urokinase-type plasminogen activator with endometrial and cervical cancer.
Obstetrics and gynecology 1988;72(2):252-6.
1988: Josef Deutinger; J C Kirchheimer; Alexander Reinthaller; Günter Christ; G Tatra; Bernd R Binder
Elevated tissue type plasminogen activator in human granulosa cells correlates with fertilizing capacity.
Human reproduction (Oxford, England) 1988;3(5):597-9.
1988: K Bartha; Johann Wojta; Oswald F Wagner; Bernd R Binder
Comparison of fibrinolytic activities of human and bovine endothelial cells.
The American journal of physiology 1988;254(6 Pt 2):R885-90.
1988: R Beckmann; Margarethe Geiger; Bernd R Binder
Plasminogen activation by tissue plasminogen activator in the presence of stimulating CNBr fragment FCB-2 of fibrinogen is a two-phase reaction. Kinetic analysis of the initial phase of slow plasmin formation.
The Journal of biological chemistry 1988;263(15):7176-80.
1988: M Maier; G Reissert; I Jerabek; F Lottspeich; Bernd R Binder
Identification of [hydroxyproline3]-lysyl-bradykinin released from human kininogens by human urinary kallikrein.
FEBS letters 1988;232(2):395-8.
1988: G Hienert; J C Kirchheimer; Günter Christ; H Pflüger; Bernd R Binder
Plasma urokinase-type plasminogen activator correlates to bone scintigraphy in prostatic carcinoma.
European urology 1988;15(3-4):256-8.
1988: F Ehrenreich; E Hattey; Johann Wojta; Bernd R Binder
Effect of anti plasminogen monoclonal antibodies on whole blood clot lysis.
Haemostasis 1988;18 Suppl 1():99-107.
1988: Margarethe Geiger; Bernd R Binder
Plasminogen activation in diabetes mellitus. Kinetics of plasmin formation with tissue plasminogen activator and plasminogen from individual diabetic donors and with in vitro glucosylated plasminogen.
Enzyme 1988;40(2-3):149-57.
1987: J C Kirchheimer; Johann Wojta; G Hienert; Günter Christ; M E Heger; H Pflüger; Bernd R Binder
Effect of urokinase on the proliferation of primary cultures of human prostatic cells.
Thrombosis research 1987;48(3):291-8.
1987: Wolfgang Speiser; Johann Wojta; C Korninger; J C Kirchheimer; J Zazgornik; Bernd R Binder
Enhanced fibrinolysis caused by tissue plasminogen activator release in hemodialysis.
Kidney international 1987;32(2):280-3.
1987: Johann Wojta; L Turcu; Oswald F Wagner; C Korninger; Bernd R Binder
Evaluation of fibrinolytic capacity by a combined assay system for tissue-type plasminogen activator antigen and function using monoclonal anti-tissue-type plasminogen activator antibodies.
The Journal of laboratory and clinical medicine 1987;109(6):665-71.
1987: E Hattey; Johann Wojta; Bernd R Binder
Monoclonal antibodies against plasminogen and alpha-2-antiplasmin: binding to native and modified antigens.
Thrombosis research 1987;45(5):485-95.
1986: Johann Wojta; J C Kirchheimer; L Turcu; Günter Christ; Bernd R Binder
Monoclonal antibodies against human high molecular weight urinary urokinase: application for affinity purification of urinary prourokinase.
Thrombosis and haemostasis 1986;55(3):347-51.
1985: J C Kirchheimer; Bernd R Binder; H Pflueger; G Hienert
Does plasma urokinase antigen reflect tumor urokinase in prostatic carcinoma?
Thrombosis and haemostasis 1985;54(3):729.
1985: J C Kirchheimer; H Pflüger; G Hienert; Bernd R Binder
Increased urokinase activity to antigen ratio in human renal-cell carcinoma.
International journal of cancer. Journal international du cancer 1985;35(6):737-41.
1985: Johann Wojta; C Korninger; J Kirchheimer; E Hattey; L Turcu; Bernd R Binder
[Use of monoclonal antibodies in the diagnosis of fibrinolysis].
Wiener klinische Wochenschrift 1985;97(5):244-8.
1985: J C Kirchheimer; H Pflüger; P Ritschl; G Hienert; Bernd R Binder
Plasminogen activator activity in bone metastases of prostatic carcinomas as compared to primary tumors.
Invasion & metastasis 1985;5(6):344-55.
1984: H Pflüger; J Kirchheimer; P Ritschl; A Köller; G Hienert; Bernd R Binder
[Tissue plasminogen activator activity in early prostatic cancer and in bone metastases of prostatic cancer].
Wiener klinische Wochenschrift 1984;96(17):658-61.
1984: J Kirchheimer; A Köller; Bernd R Binder
Isolation and characterization of plasminogen activators from hyperplastic and malignant prostate tissue.
Biochimica et biophysica acta 1984;797(2):256-65.
1984: A Köller; J Kirchheimer; H Pflüger; Bernd R Binder
Tissue plasminogen activator activity in prostatic cancer.
European urology 1984;10(6):389-94.