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Kathleen Ryan

Research Profile

Living Beings

Amish

Geographic Areas

Pennsylvania

Concepts & Ideas

Disorders

Genes & Molecular Sequences

Single Nucleotide Polymorphism

Physiology

Procedures

Chemicals & Drugs

Cytoplasmic Aspartate Aminotransferase

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Publications

TOP 3
Richard B Horenstein; Dieter Lütjohann; Braxton D Mitchell; Wendy S Post; Kathleen A Ryan; Alan R Shuldiner; Michael L Terrin; Klaus Von Bergmann; Nanette I Steinle
The ABCG8 G574R variant, serum plant sterol levels, and cardiovascular disease risk in the Old Order Amish.
Yun Hu; Braxton D Mitchell; Kathleen A Ryan; Alan R Shuldiner; Soren Snitker; Rong-Ze Yang; Dalong Zhu; Da-Wei Gong
Serum alanine aminotransferase is correlated with hematocrit in healthy human subjects.
Charles D Howell; Chadi Ibrahim; John G McHutchison; Nezam H Afdhal; Michael Fried; David B Goldstein; Alexis Gorden; Kathleen A Ryan; Kevin V Shianna; Alan R Shuldiner; Alexander J Thompson; Braxton D Mitchell
Single nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1.

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All Publications

2013: Richard B Horenstein; Dieter Lütjohann; Braxton D Mitchell; Wendy S Post; Kathleen A Ryan; Alan R Shuldiner; Michael L Terrin; Klaus Von Bergmann; Nanette I Steinle
The ABCG8 G574R variant, serum plant sterol levels, and cardiovascular disease risk in the Old Order Amish.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(2):413-9.
2012: Yun Hu; Braxton D Mitchell; Kathleen A Ryan; Alan R Shuldiner; Soren Snitker; Rong-Ze Yang; Dalong Zhu; Da-Wei Gong
Serum alanine aminotransferase is correlated with hematocrit in healthy human subjects.
Scandinavian journal of clinical and laboratory investigation 2012;72(3):258-64.
2012: Charles D Howell; Chadi Ibrahim; John G McHutchison; Nezam H Afdhal; Michael Fried; David B Goldstein; Alexis Gorden; Kathleen A Ryan; Kevin V Shianna; Alan R Shuldiner; Alexander J Thompson; Braxton D Mitchell
Single nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1.
Journal of hepatology 2012;56(3):557-63.
2012: Braxton D Mitchell; Toni I Pollin; Kathleen A Ryan; Zahra Ashktorab; Woei-Jyh Lee; Laurence S Magder; Patrick F McArdle; Kelsey Shields; Alan R Shuldiner; Magdalena Tolea; Alejandro A Schäffer
Living the good life? Mortality and hospital utilization patterns in the Old Order Amish.
PloS one 2012;7(12):e51560.
2012: Margaret L Zupancic; Brandi L Cantarel; Shana Cirimotich; Elliott F Drabek; Richard B Horenstein; Cheron Jones; Rob Knight; Daniel Knights; Zhenqiu Liu; Braxton D Mitchell; Emmanuel F Mongodin; Kathleen A Ryan; Alan R Shuldiner; Soren Snitker; Nanette I Steinle; William A Walters; Claire M Fraser-Liggett
Analysis of the gut microbiota in the old order Amish and its relation to the metabolic syndrome.
PloS one 2012;7(8):e43052.
2011: Haiqing Shen; Scott R Shuldiner; Rong-Ze Yang; Hong Hu; Braxton D Mitchell; Kathleen A Ryan; Sumbul Chai; Coleen M Damcott; Quince Gibson; Da-Wei Gong
Genome-wide association study identifies genetic variants in GOT1 determining serum aspartate aminotransferase levels.
Journal of human genetics 2011;56(11):801-5.
2010: Haiqing Shen; Coleen M Damcott; Evadnie Rampersaud; Toni I Pollin; Richard B Horenstein; Patrick F McArdle; Patricia A Peyser; Lawrence F Bielak; Wendy S Post; Yen-Pei C Chang; Kathleen A Ryan; Michael Miller; John A Rumberger; Patrick F Sheedy; John Shelton; Jeffrey R O'Connell; Alan R Shuldiner; Braxton D Mitchell
Familial defective apolipoprotein B-100 and increased low-density lipoprotein cholesterol and coronary artery calcification in the old order amish.
Archives of internal medicine 2010;170(20):1850-5.
2010: Kiran Musunuru; Wendy S Post; WILLIAM HERZOG; Haiqing Shen; Jeffrey R O'Connell; Patrick F McArdle; Kathleen A Ryan; Quince Gibson; Yu-Ching Cheng; Elizabeth Clearfield; Andrew D Johnson; Geoffrey Tofler; Qiong Yang; Christopher J O'Donnell; Diane M Becker; Lisa R Yanek; Lewis C Becker; Nauder Faraday; Lawrence F Bielak; Patricia A Peyser; Alan R Shuldiner; Braxton D Mitchell
Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease.
Circulation. Cardiovascular genetics 2010;3(5):445-53.
2010: Yu-Ching Cheng; WEN KAO; Braxton D Mitchell; ALBERT SHARRETT; Kathleen A Ryan; Robert A Vogel; Alan R Shuldiner; Toni I Pollin
Genetic effects on postprandial variations of inflammatory markers in healthy individuals.
Obesity (Silver Spring, Md.) 2010;18(7):1417-22.
2009: Haiqing Shen; WILLIAM HERZOG; MaryAnn Drolet; Ruth Pakyz; Sylvia Newcomer; Paul Sack; Heidi Karon; Kathleen A Ryan; Yiju Zhao; Xiaolian Shi; Braxton D Mitchell; Alan R Shuldiner
Aspirin Resistance in healthy drug-naive men versus women (from the Heredity and Phenotype Intervention Heart Study).
The American journal of cardiology 2009;104(4):606-12.
2009: Yu-Ching Cheng; WEN KAO; Braxton D Mitchell; Jeffrey R O'Connell; Haiqing Shen; Patrick F McArdle; Quince Gibson; Kathleen A Ryan; Alan R Shuldiner; Toni I Pollin
Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels.
Circulation. Cardiovascular genetics 2009;2(4):329-37.
2009: Erin D Michos; Elizabeth A Streeten; Kathleen A Ryan; Evadnie Rampersaud; Patricia A Peyser; Lawrence F Bielak; Alan R Shuldiner; Braxton D Mitchell; Wendy S Post
Serum 25-hydroxyvitamin d levels are not associated with subclinical vascular disease or C-reactive protein in the old order amish.
Calcified tissue international 2009;84(3):195-202.
2009: Lawrence F Bielak; Richard B Horenstein; Kathleen A Ryan; Patrick F Sheedy; John A Rumberger; Keith Tanner; Wendy S Post; Braxton D Mitchell; Alan R Shuldiner; Patricia A Peyser
Circulating CD34+ Cell Count is Associated with Extent of Subclinical Atherosclerosis in Asymptomatic Amish Men, Independent of 10-Year Framingham Risk.
Clinical medicine. Cardiology 2009;3():53-60.
2008: Evadnie Rampersaud; Lawrence F Bielak; Afshin Parsa; Haiqing Shen; Wendy S Post; Kathleen A Ryan; Patrick Donnelly; John A Rumberger; Patrick F Sheedy; Patricia A Peyser; Alan R Shuldiner; Braxton D Mitchell
The association of coronary artery calcification and carotid artery intima-media thickness with distinct, traditional coronary artery disease risk factors in asymptomatic adults.
American journal of epidemiology 2008;168(9):1016-23.
2008: Braxton D Mitchell; Patrick F McArdle; Haiqing Shen; Evadnie Rampersaud; Toni I Pollin; Lawrence F Bielak; Cashell Jaquish; Julie A Douglas; Marie-Hélène Roy-Gagnon; Paul Sack; Rosalie Naglieri; Scott Hines; Richard B Horenstein; Yen-Pei C Chang; Wendy S Post; Kathleen A Ryan; Nga Hong Brereton; Ruth E Pakyz; John D Sorkin; Coleen M Damcott; Jeffrey R O'Connell; Charles Mangano; Mary C Corretti; Robert A Vogel; WILLIAM HERZOG; Matthew R Weir; Patricia A Peyser; Alan R Shuldiner
The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study.
American heart journal 2008;155(5):823-8.
2008: Marie-Hélène Roy-Gagnon; Matthew R Weir; John D Sorkin; Kathleen A Ryan; Paul A Sack; Scott Hines; Lawrence F Bielak; Patricia A Peyser; Wendy S Post; Braxton D Mitchell; Alan R Shuldiner; Julie A Douglas
Genetic influences on blood pressure response to the cold pressor test: results from the Heredity and Phenotype Intervention Heart Study.
Journal of hypertension 2008;26(4):729-36.
2008: Elizabeth A Streeten; Kashif Munir; Scott Hines; Asif Mohamed; Charles Mangano; Kathleen A Ryan; Wendy S Post
Coronary artery calcification in patients with primary hyperparathyroidism in comparison with control subjects from the multi-ethnic study of atherosclerosis.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2008;14(2):155-61.
2008: Lawrence F Bielak; Panfong Yu; Kathleen A Ryan; John A Rumberger; Patrick F Sheedy; Stephen T Turner; Wendy S Post; Alan R Shuldiner; Braxton D Mitchell; Patricia A Peyser
Differences in prevalence and severity of coronary artery calcification between two non-Hispanic white populations with diverse lifestyles.
Atherosclerosis 2008;196(2):888-95.
2007: Haiqing Shen; Lawrence F Bielak; Elizabeth A Streeten; Kathleen A Ryan; John A Rumberger; Patrick F Sheedy; Alan R Shuldiner; Patricia A Peyser; Braxton D Mitchell
Relationship between vascular calcification and bone mineral density in the Old-order Amish.
Calcified tissue international 2007;80(4):244-50.
2007: Wendy S Post; Lawrence F Bielak; Kathleen A Ryan; Yu-Ching Cheng; Haiqing Shen; John A Rumberger; Patrick F Sheedy; Alan R Shuldiner; Patricia A Peyser; Braxton D Mitchell
Determinants of coronary artery and aortic calcification in the Old Order Amish.
Circulation 2007;115(6):717-24.
2007: Wendy S Post; Haiqing Shen; Coleen M Damcott; Dan E Arking; WEN KAO; Paul A Sack; Kathleen A Ryan; Aravinda Chakravarti; Braxton D Mitchell; Alan R Shuldiner
Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac repolarization in the old order Amish.
Human heredity 2007;64(4):214-9.
2005: Elizabeth A Streeten; Kathleen A Ryan; Daniel J McBride; Toni I Pollin; Alan R Shuldiner; Braxton D Mitchell
The relationship between parity and bone mineral density in women characterized by a homogeneous lifestyle and high parity.
The Journal of clinical endocrinology and metabolism 2005;90(8):4536-41.