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Alexey Ryazanov

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Chemicals & Drugs

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Phosphorylation

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Elena Nosyreva; Alexey G Ryazanov; Kristen Szabla; Anita E Autry; Lisa M Monteggia; Ege T Kavalali
Acute suppression of spontaneous neurotransmission drives synaptic potentiation.
Asli A Hizli; Yi Liao; Alexey G Ryazanov; Jherek Swanger; Markus Welcker; John H Carter; Yong Chi; Bruce E Clurman
Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase.
Olga Abramczyk; Ashwini K Devkota; Bulent Ozpolat; Austen F Riggs; Alexey G Ryazanov; Clint D J Tavares; Benjamin E Turk; Kevin N Dalby
Purification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli.

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All Publications

2013: Elena Nosyreva; Alexey G Ryazanov; Kristen Szabla; Anita E Autry; Lisa M Monteggia; Ege T Kavalali
Acute suppression of spontaneous neurotransmission drives synaptic potentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(16):6990-7002.
2013: Asli A Hizli; Yi Liao; Alexey G Ryazanov; Jherek Swanger; Markus Welcker; John H Carter; Yong Chi; Bruce E Clurman
Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase.
Molecular and cellular biology 2013;33(3):596-604.
2011: Olga Abramczyk; Ashwini K Devkota; Bulent Ozpolat; Austen F Riggs; Alexey G Ryazanov; Clint D J Tavares; Benjamin E Turk; Kevin N Dalby
Purification and characterization of tagless recombinant human elongation factor 2 kinase (eEF-2K) expressed in Escherichia coli.
Protein expression and purification 2011;79(2):237-44.
2011: Martin A Bewley; Trong K Pham; Helen M Marriott; Josselin Noirel; Hseuh-Ping Chu; Saw Yen Ow; Alexey G Ryazanov; Robert C Read; Moira K B Whyte; Benny Chain; Phillip C Wright; David H Dockrell
Proteomic evaluation and validation of cathepsin D regulated proteins in macrophages exposed to Streptococcus pneumoniae.
Molecular & cellular proteomics : MCP 2011;10(6):M111.008193.
2011: Maxim V Dorovkov; Alla S Kostyukova; Alexey G Ryazanov
Phosphorylation of annexin A1 by TRPM7 kinase: a switch regulating the induction of an α-helix.
Biochemistry 2011;50(12):2187-93.
2011: Anne-Laure Perraud; Xiaoyun Zhao; Alexey G Ryazanov; Carsten Schmitz
The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k.
Cellular signalling 2011;23(3):586-93.
2010: Aslam A Khan; Dru S Dace; Alexey G Ryazanov; Jennifer Kelly; Rajendra S Apte
Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase-regulated pathway.
The American journal of pathology 2010;177(1):481-92.
2008: Kristopher Clark; Jeroen Middelbeek; Maxim V Dorovkov; Carl G Figdor; Alexey G Ryazanov; Edwin Lasonder; Frank N Van Leeuwen
The alpha-kinases TRPM6 and TRPM7, but not eEF-2 kinase, phosphorylate the assembly domain of myosin IIA, IIB and IIC.
FEBS letters 2008;582(20):2993-7.
2008: Sungjin Park; Joo Min Park; Sangmok Kim; Jin-Ah Kim; Jason D Shepherd; CONSTANCE SMITH HICKS; Shoaib Chowdhury; Walter E Kaufmann; Dietmar Kuhl; Alexey G Ryazanov; Richard Huganir; David J Linden; Paul F Worley
Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD.
Neuron 2008;59(1):70-83.
2008: Kristopher Clark; Jeroen Middelbeek; Edwin Lasonder; Natalya G Dulyaninova; Nick A Morrice; Alexey G Ryazanov; Anne R Bresnick; Carl G Figdor; Frank N Van Leeuwen
TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation.
Journal of molecular biology 2008;378(4):790-803.
2007: Eszter S Hars; Haiyan Qi; Alexey G Ryazanov; Shengkan Jin; li cai; Chengcheng Hu; Leroy F Liu
Autophagy regulates ageing in C. elegans.
Autophagy 2007;3(2):93-5.
2006: Kristopher Clark; Michiel Langeslag; Bart van Leeuwen; Leonie Ran; Alexey G Ryazanov; Carl G Figdor; Wouter H Moolenaar; Kees Jalink; Frank N Van Leeuwen
TRPM7, a novel regulator of actomyosin contractility and cell adhesion.
The EMBO journal 2006;25(2):290-301.
2005: Carsten Schmitz; Maxim V Dorovkov; Xiaoyun Zhao; Bennett J Davenport; Alexey G Ryazanov; Anne-Laure Perraud
The channel kinases TRPM6 and TRPM7 are functionally nonredundant.
The Journal of biological chemistry 2005;280(45):37763-71.
2005: Meredith C Hermosura; Hannah Nayakanti; Maxim V Dorovkov; Fernanda R Calderon; Alexey G Ryazanov; David S Haymer; Ralph M Garruto
A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11510-5.
2005: Martin Heine; Catharina I Cramm-Behrens; Athar I Ansari; Hsueh-Ping Chu; Alexey G Ryazanov; Hassan Y Naim; Ralf Jacob
Alpha-kinase 1, a new component in apical protein transport.
The Journal of biological chemistry 2005;280(27):25637-43.
2004: Maxim V Dorovkov; Alexey G Ryazanov
Phosphorylation of annexin I by TRPM7 channel-kinase.
The Journal of biological chemistry 2004;279(49):50643-6.
2004: Diana Drennan; Alexey G Ryazanov
Alpha-kinases: analysis of the family and comparison with conventional protein kinases.
Progress in biophysics and molecular biology 2004;85(1):1-32.
2004: Lillia V Ryazanova; Maxim V Dorovkov; Athar I Ansari; Alexey G Ryazanov
Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel.
The Journal of biological chemistry 2004;279(5):3708-16.
2002: Maxim V Dorovkov; Karen S Pavur; Alexey N Petrov; Alexey G Ryazanov
Regulation of elongation factor-2 kinase by pH.
Biochemistry 2002;41(45):13444-50.
2002: Alexey G Ryazanov
Elongation factor-2 kinase and its newly discovered relatives.
FEBS letters 2002;514(1):26-9.
2002: Alexey G Ryazanov; Bradley S Nefsky
Protein turnover plays a key role in aging.
Mechanisms of ageing and development 2002;123(2-3):207-13.
2000: Karen S Pavur; Alexey N Petrov; Alexey G Ryazanov
Mapping the functional domains of elongation factor-2 kinase.
Biochemistry 2000;39(40):12216-24.
1999: Steven A Enkemann; Karen S Pavur; Alexey G Ryazanov; SL Berger
Does prothymosin alpha affect the phosphorylation of elongation factor 2?
The Journal of biological chemistry 1999;274(26):18644-50.
1999: Alexey G Ryazanov; Karen S Pavur; Maxim V Dorovkov
Alpha-kinases: a new class of protein kinases with a novel catalytic domain.
Current biology : CB 1999;9(2):R43-5.
1998: A L Laitusis; Charles O Brostrom; Alexey G Ryazanov; Margaret A Brostrom
An examination of the role of increased cytosolic free Ca2+ concentrations in the inhibition of mRNA translation.
Archives of biochemistry and biophysics 1998;354(2):270-80.
1997: Alexey G Ryazanov; MD Ward; C E Mendola; Karen S Pavur; Maxim V Dorovkov; M Wiedmann; Hediye Erdjument-Bromage; Paul Tempst; TG Parmer; C R Prostko; F Joseph Germino; William N Hait
Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):4884-9.
1996: William N Hait; M D Ward; I N Trakht; Alexey G Ryazanov
Elongation factor-2 kinase: immunological evidence for the existence of tissue-specific isoforms.
FEBS letters 1996;397(1):55-60.