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Markku Ryynänen

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Finland

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Jaana Tolvanen; Outi Uimari; Lauri A Aaltonen; Markku Ryynänen; Pia Vahteristo
Strong family history of uterine leiomyomatosis warrants fumarate hydratase mutation screening.
M Sahraravand; Aydin Tekay; Ilkka Y Järvelä; P Laitinen; Markku Ryynänen
The secretion of PAPP-A, ADAM12, and PP13 correlates with the size of the placenta for the first month of pregnancy.
Katri Koli; Markku Ryynänen; Jorma Keski-Oja
Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells.

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All Publications

2012: Jaana Tolvanen; Outi Uimari; Lauri A Aaltonen; Markku Ryynänen; Pia Vahteristo
Strong family history of uterine leiomyomatosis warrants fumarate hydratase mutation screening.
Human reproduction (Oxford, England) 2012;27(6):1865-9.
2011: M Sahraravand; Aydin Tekay; Ilkka Y Järvelä; P Laitinen; Markku Ryynänen
The secretion of PAPP-A, ADAM12, and PP13 correlates with the size of the placenta for the first month of pregnancy.
Placenta 2011;32(12):999-1003.
2008: Katri Koli; Markku Ryynänen; Jorma Keski-Oja
Latent TGF-beta binding proteins (LTBPs)-1 and -3 coordinate proliferation and osteogenic differentiation of human mesenchymal stem cells.
Bone 2008;43(4):679-88.
2007: Jaana M Hartikainen; Vesa Kataja; Mia Pirskanen; Airi Arffman; Ulla Ristonmaa; Pia Vahteristo; Markku Ryynänen; Seppo Heinonen; Veli-Matti Kosma; Arto Mannermaa
Screening for BRCA1 and BRCA2 mutations in Eastern Finnish breast/ovarian cancer families.
Clinical genetics 2007;72(4):311-20.
2007: Jouko Järvenpää; Ursula Schwab; Tiina Lappalainen; Mervi Päkkilä; Leo Niskanen; Kari Punnonen; Markku Ryynänen
Fortified mineral water improves folate status and decreases plasma homocysteine concentration in pregnant women.
Journal of perinatal medicine 2007;35(2):108-14.
2007: Aila Rissanen; Marko Niemimaa; Mikko Suonpää; Markku Ryynänen; Seppo Heinonen
First trimester Down's syndrome screening shows high detection rate for trisomy 21, but poor performance in structural abnormalities--regional outcome results.
Fetal diagnosis and therapy 2007;22(1):45-50.
2006: A Rissanen; Marko Niemimaa; Mikko Suonpää; Markku Ryynänen; Seppo Heinonen
Pregnancy-associated plasma protein A, free human chorionic gonadotrophin and nuchal translucency as predictors of miscarriage.
Clinical genetics 2006;69(3):287-9.
2004: Markku Ryynänen; Aydin Tekay; Marko Niemimaa; Pekka Taipale; Seppo Heinonen
[How to improve screening of Down syndrome].
Duodecim; lääketieteellinen aikakauskirja 2004;120(3):354-5; author reply 355-6.
2003: Marko Niemimaa; Seppo Heinonen; Maija Seppälä; Markku Ryynänen
The influence of smoking on the pregnancy-associated plasma protein A, free beta human chorionic gonadotrophin and nuchal translucency.
BJOG : an international journal of obstetrics and gynaecology 2003;110(7):664-7.
2003: Maija Castren; Ari Pääkkönen; Ina Tarkka; Markku Ryynänen; Juhani Partanen
Augmentation of auditory N1 in children with fragile X syndrome.
Brain topography 2003;15(3):165-71.
2002: Jane M Olson; Sompong Vongpunsawad; Helena Kuivaniemi; Antti Ronkainen; Juha Hernesniemi; Markku Ryynänen; Lee-Lian Kim; Gerard Tromp
Search for intracranial aneurysm susceptibility gene(s) using Finnish families.
BMC medical genetics 2002;3():7.
2002: Jaakko Patrakka; Paula Martin; Riitta Salonen; Marjo Kestilä; Vesa Ruotsalainen; Minna Männikkö; Markku Ryynänen; Juhani Rapola; Christer Holmberg; Karl Tryggvason; Hannu Jalanko
Proteinuria and prenatal diagnosis of congenital nephrosis in fetal carriers of nephrin gene mutations.
Lancet 2002;359(9317):1575-7.
2002: Gabriele Richard; Fatima Rouan; Colin Willoughby; Nkecha Brown; Pil Chung; Markku Ryynänen; Ethylin Jabs; Sherri J Bale; John J DiGiovanna; Jouni Uitto; Laura Russell
Missense mutations in GJB2 encoding connexin-26 cause the ectodermal dysplasia keratitis-ichthyosis-deafness syndrome.
American journal of human genetics 2002;70(5):1341-8.
2002: Marko Niemimaa; Mikko Suonpää; Seppo Heinonen; Maija Seppälä; Risto Bloigu; Markku Ryynänen
Maternal serum human chorionic gonadotrophin and pregnancy-associated plasma protein A in twin pregnancies in the first trimester.
Prenatal diagnosis 2002;22(3):183-5.
2002: Antti Perheentupa; Aimo Ruokonen; Leena Tuomivaara; Markku Ryynänen; Hannu Martikainen
Maternal serum beta-HCG and alpha-fetoprotein concentrations in singleton pregnancies following assisted reproduction.
Human reproduction (Oxford, England) 2002;17(3):794-7.
2001: Marko Niemimaa; Seppo Heinonen; Markku Seppala; Maritta Hippeläinen; Hannu Martikainen; Markku Ryynänen
First-trimester screening for Down's syndrome in in vitro fertilization pregnancies.
Fertility and sterility 2001;76(6):1282-3.
2001: Mikko Hiltunen; Arto Mannermaa; D Thompson; D Easton; Mia Pirskanen; Seppo Helisalmi; Anne Maria Koivisto; Maarit Lehtovirta; Markku Ryynänen; Hilkka Soininen
Genome-wide linkage disequilibrium mapping of late-onset Alzheimer's disease in Finland.
Neurology 2001;57(9):1663-8.
2001: Marko Niemimaa; Mikko Suonpää; Antti Perheentupa; Maija Seppälä; Seppo Heinonen; Päivi Laitinen; Aimo Ruokonen; Markku Ryynänen
Evaluation of first trimester maternal serum and ultrasound screening for Down's syndrome in Eastern and Northern Finland.
European journal of human genetics : EJHG 2001;9(6):404-8.
2001: J Kallinen; K Marin; Seppo Heinonen; Arto Mannermaa; A Palotie; Markku Ryynänen
Wide scope prenatal diagnosis at Kuopio University Hospital 1997-1998: integration of gene tests and fetal karyotyping.
BJOG : an international journal of obstetrics and gynaecology 2001;108(5):505-9.
2001: J Kallinen; Seppo Heinonen; Markku Ryynänen; L Pulkkinen; Arto Mannermaa
Antenatal genetic screening for congenital nephrosis.
Prenatal diagnosis 2001;21(2):81-4.
2001: Mervi Päkkilä; Marko Niemimaa; Pertti Kirkinen; Markku Ryynänen
[Antenatal screening methods for chromosome 21 trisomy].
Duodecim; lääketieteellinen aikakauskirja 2001;117(3):269-74; quiz 274, 281.
2000: Laura Sarantaus; Pia Huusko; Hannaleena Eerola; Virpi Launonen; Paula Vehmanen; Katrin Rapakko; Elizabeth M Gillanders; Kirsi Syrjäkoski; Tommi Kainu; Pia Vahteristo; Ralf Krahe; Kimmo Pääkkönen; J Hartikainen; Carl Blomqvist; T Löppönen; Kaija Holli; Markku Ryynänen; Ralf Bützow; Ake Borg; B Wasteson Arver; E Holmberg; Arto Mannermaa; Juha Kere; Olli Kallioniemi; Robert Winqvist; Heli Nevanlinna
Multiple founder effects and geographical clustering of BRCA1 and BRCA2 families in Finland.
European journal of human genetics : EJHG 2000;8(10):757-63.
2000: J Kallinen; Seppo Heinonen; Arto Mannermaa; Markku Ryynänen
Prenatal diagnosis of fragile X syndrome and the risk of expansion of a premutation.
Clinical genetics 2000;58(2):111-5.
2000: J Kallinen; K Korhonen; S Kortelainen; Seppo Heinonen; Markku Ryynänen
Pregnancy outcome in carriers of fragile X.
BJOG : an international journal of obstetrics and gynaecology 2000;107(8):969-72.
2000: Anna-Mari Heikkinen; Heikki Kröger; Leo Niskanen; Marja Komulainen; Markku Ryynänen; Markku Parviainen; Marjo Tuppurainen; Risto Honkanen; Seppo Saarikoski
Does apolipoprotein E genotype relate to BMD and bone markers in postmenopausal women?
Maturitas 2000;34(1):33-41.
2000: Seppo Helisalmi; Mikko Hiltunen; Arto Mannermaa; Anne Maria Koivisto; Maarit Lehtovirta; Irina Alafuzoff; Markku Ryynänen; Hilkka Soininen
Is the presenilin-1 E318G missense mutation a risk factor for Alzheimer's disease?
Neuroscience letters 2000;278(1-2):65-8.
2000: Seppo Heinonen; Markku Ryynänen; Pertti Kirkinen
Etiology and outcome of second trimester non-immunologic fetal hydrops.
Acta obstetricia et gynecologica Scandinavica 2000;79(1):15-8.
1999: Seppo Heinonen; Christian Breymann; Markku Ryynänen; K Gautschi; Renate Huch; Albert Huch; Pertti Kirkinen
Unexplained elevated serum hCG is associated with raised amniotic fluid erythropoietin levels in second-trimester pregnancies.
Fetal diagnosis and therapy 1999;14(5):286-90.
1999: Seppo Helisalmi; Mikko Hiltunen; Piia Valonen; Arto Mannermaa; Anne Maria Koivisto; Maarit Lehtovirta; Markku Ryynänen; Hilkka Soininen
Promoter polymorphism (-491A/T) in the APOE gene of Finnish Alzheimer's disease patients and control individuals.
Journal of neurology 1999;246(9):821-4.
1999: Mikko Hiltunen; Arto Mannermaa; Anne Maria Koivisto; Maarit Lehtovirta; Seppo Helisalmi; Markku Ryynänen; PJ Riekkinen; Hilkka Soininen
Linkage disequilibrium in the 13q12 region in Finnish late onset Alzheimer's disease patients.
European journal of human genetics : EJHG 1999;7(6):652-8.
1999: Seppo Heinonen; Markku Ryynänen; Pertti Kirkinen
The effects on fetal development of high alpha-fetoprotein and maternal smoking.
American journal of public health 1999;89(4):561-3.
1999: Markku Ryynänen; Seppo Heinonen; M Makkonen; E Kajanoja; Arto Mannermaa; K Pertti
Feasibility and acceptance of screening for fragile X mutations in low-risk pregnancies.
European journal of human genetics : EJHG 1999;7(2):212-6.
1999: Anna-Mari Heikkinen; Leo Niskanen; Markku Ryynänen; Marja Komulainen; Marjo Tuppurainen; Markku Parviainen; Seppo Saarikoski
Is the response of serum lipids and lipoproteins to postmenopausal hormone replacement therapy modified by ApoE genotype?
Arteriosclerosis, thrombosis, and vascular biology 1999;19(2):402-7.
1998: Mikko Hiltunen; Arto Mannermaa; Seppo Helisalmi; Anne Maria Koivisto; Maarit Lehtovirta; Markku Ryynänen; PJ Riekkinen; Hilkka Soininen
Butyrylcholinesterase K variant and apolipoprotein E4 genes do not act in synergy in Finnish late-onset Alzheimer's disease patients.
Neuroscience letters 1998;250(1):69-71.
1998: Maarit Lehtovirta; Jyrki Kuikka; Seppo Helisalmi; Päivi Hartikainen; Arto Mannermaa; Markku Ryynänen; Hilkka Soininen
Longitudinal SPECT study in Alzheimer's disease: relation to apolipoprotein E polymorphism.
Journal of neurology, neurosurgery, and psychiatry 1998;64(6):742-6.
1998: Markku Ryynänen; Seppo Heinonen; M Makkonen; Arto Mannermaa; Pertti Kirkinen
[Screening for Fragile X syndrome mutations during early pregnancy--results and mothers' opinions about the gene test].
Duodecim; lääketieteellinen aikakauskirja 1998;22(114):2323-9.
1997: Pertti Kirkinen; Kaarina Partanen; J Merikanto; Markku Ryynänen; P Haring; K Heinonen
Ultrasonic and magnetic resonance imaging of fetal sacrococcygeal teratoma.
Acta obstetricia et gynecologica Scandinavica 1997;76(10):917-22.
1997: Markku Ryynänen; S Leskinen; Seppo Heinonen; Pertti Kirkinen
Recurrence risk of a serious, noninherited chromosomal abnormality.
Fertility and sterility 1997;68(3):439-42.
1997: Pertti Kirkinen; Kaarina Partanen; Markku Ryynänen; Maija-Riitta Ordén
Fetal intracranial hemorrhage. Imaging by ultrasound and magnetic resonance imaging.
The Journal of reproductive medicine 1997;42(8):467-72.
1997: Seppo Helisalmi; Arto Mannermaa; Maarit Lehtovirta; Markku Ryynänen; PJ Riekkinen; Hilkka Soininen
No association between alpha1-antichymotrypsin polymorphism, apolipoprotein E and patients with late-onset Alzheimer's disease.
Neuroscience letters 1997;231(1):56-8.
1997: UM Agren; Markku Tammi; Markku Ryynänen; Raija Tammi
Developmentally programmed expression of hyaluronan in human skin and its appendages.
The Journal of investigative dermatology 1997;109(2):219-24.
1997: Pekka Jäkälä; Tuomo Hänninen; Markku Ryynänen; Markku Laakso; Kaarina Partanen; Arto Mannermaa; Hilkka Soininen
Fragile-X: neuropsychological test performance, CGG triplet repeat lengths, and hippocampal volumes.
The Journal of clinical investigation 1997;100(2):331-8.
1997: A Heikkilä; Markku Ryynänen; Pertti Kirkinen; S Saarikoski
Results and views of women in population-wide pregnancy screening for trisomy 21 in east Finland.
Fetal diagnosis and therapy 1997;12(2):93-6.
1997: Antti Ronkainen; Juha Hernesniemi; Matti Puranen; Lea Niemitukia; Ritva Vanninen; Markku Ryynänen; Helena Kuivaniemi; Gerard Tromp
Familial intracranial aneurysms.
Lancet 1997;349(9049):380-4.
1997: B Gatalica; Leena Pulkkinen; K Li; K Kuokkanen; Markku Ryynänen; John A McGrath; Jouni Uitto
Cloning of the human type XVII collagen gene (COL17A1), and detection of novel mutations in generalized atrophic benign epidermolysis bullosa.
American journal of human genetics 1997;60(2):352-65.
1997: Pertti Kirkinen; Seppo Heinonen; Kari Vanamo; Markku Ryynänen
Maternal serum alpha-fetoprotein and epithelial tumour marker concentrations are not increased by fetal sacrococcygeal teratoma.
Prenatal diagnosis 1997;17(1):47-50.
1996: Seppo Heinonen; Markku Ryynänen; Pertti Kirkinen; S Saarikoski
Elevated midtrimester maternal serum hCG in chromosomally normal pregnancies is associated with preeclampsia and velamentous umbilical cord insertion.
American journal of perinatology 1996;13(7):437-41.
1996: Seppo Heinonen; Markku Ryynänen; Pertti Kirkinen; M Hippeläinen; S Saarikoski
Effect of in vitro fertilization on human chorionic gonadotropin serum concentrations and Down's syndrome screening.
Fertility and sterility 1996;66(3):398-403.
1996: Nanbert Zhong; Weina Ju; D Curley; D Wang; J Pietrofesa; G Wu; Y Shen; C Pang; P Poon; X Liu; S Gou; E Kajanoja; Markku Ryynänen; Carl Dobkin; W Ted Brown
A survey of FRAXE allele sizes in three populations.
American journal of medical genetics 1996;64(2):415-9.
1996: Arto Mannermaa; L Pulkkinen; E Kajanoja; Markku Ryynänen; S Saarikoski
Deletion in the FMR1 gene in a fragile-X male.
American journal of medical genetics 1996;64(2):293-5.
1996: Nanbert Zhong; E Kajanoja; B Smits; J Pietrofesa; D Curley; D Wang; Weina Ju; Sarah L Nolin; Carl Dobkin; Markku Ryynänen; W Ted Brown
Fragile X founder effects and new mutations in Finland.
American journal of medical genetics 1996;64(1):226-33.
1996: Seppo Heinonen; Markku Ryynänen; Pertti Kirkinen; S Saarikoski
Uterine malformation: a cause of elevated maternal serum alpha-fetoprotein concentrations.
Prenatal diagnosis 1996;16(7):635-9.
1996: Maarit Lehtovirta; J Partanen; M Könönen; Hilkka Soininen; Seppo Helisalmi; Arto Mannermaa; Markku Ryynänen; Päivi Hartikainen; PJ Riekkinen
Spectral analysis of EEG in Alzheimer's disease: relation to apolipoprotein E polymorphism.
Neurobiology of aging 1996;17(4):523-6.
1996: Seppo Heinonen; Markku Ryynänen; Pertti Kirkinen; S Saarikoski
Endometrial and fetoplacental markers in pregnancies with fetal congenital nephrosis.
Acta obstetricia et gynecologica Scandinavica 1996;75(6):526-30.
1996: Maarit Lehtovirta; Hilkka Soininen; Mikko P Laakso; Kaarina Partanen; Seppo Helisalmi; Arto Mannermaa; Markku Ryynänen; Jyrki Kuikka; Päivi Hartikainen; PJ Riekkinen
SPECT and MRI analysis in Alzheimer's disease: relation to apolipoprotein E epsilon 4 allele.
Journal of neurology, neurosurgery, and psychiatry 1996;60(6):644-9.
1996: Pertti Kirkinen; W Serlo; P Jouppila; Markku Ryynänen; Anneli Martikainen
Long-term outcome of fetal hydrocephaly.
Journal of child neurology 1996;11(3):189-92.
1996: Seppo Heinonen; Markku Ryynänen; Pertti Kirkinen; I Penttilä; K Syrjänen; Markku Seppala; S Saarikoski
Prenatal screening for congenital nephrosis in east Finland: results and impact on the birth prevalence of the disease.
Prenatal diagnosis 1996;16(3):207-13.
1996: Seppo Heinonen; Markku Ryynänen; Pertti Kirkinen; S Saarikoski
Velamentous umbilical cord insertion may be suspected from maternal serum alpha-fetoprotein and hCG.
British journal of obstetrics and gynaecology 1996;103(3):209-13.
1996: Seppo Helisalmi; Arto Mannermaa; Maarit Lehtovirta; Markku Ryynänen; PJ Riekkinen; Hilkka Soininen
Screening for amyloid beta precursor protein codon 665, 670/671 and 717 mutations in Finnish patients with Alzheimer's disease.
Neuroscience letters 1996;205(1):68-70.
1996: Seppo Helisalmi; K Linnaranta; Maarit Lehtovirta; Arto Mannermaa; Outi Kopra; Markku Ryynänen; PJ Riekkinen; Hilkka Soininen
Apolipoprotein E polymorphism in patients with different neurodegenerative disorders.
Neuroscience letters 1996;205(1):61-4.
1996: Maarit Lehtovirta; Hilkka Soininen; Seppo Helisalmi; Arto Mannermaa; Eeva-Liisa Helkala; Päivi Hartikainen; Tuomo Hänninen; Markku Ryynänen; PJ Riekkinen
Clinical and neuropsychological characteristics in familial and sporadic Alzheimer's disease: relation to apolipoprotein E polymorphism.
Neurology 1996;46(2):413-9.
1996: S Leskinen; Markku Ryynänen; Pertti Kirkinen; Seppo Heinonen; S Saarikoski
[Risk of recurrence of non inherited chromosomal abnormalities].
Duodecim; lääketieteellinen aikakauskirja 1996;112(13):1172-6.
1996: Seppo Heinonen; Markku Ryynänen; Pertti Kirkinen; S Saarikoski
Perinatal diagnostic evaluation of velamentous umbilical cord insertion: clinical, Doppler, and ultrasonic findings.
Obstetrics and gynecology 1996;87(1):112-7.
1995: Outi Kopra; Maarit Lehtovirta; Hilkka Soininen; Seppo Helisalmi; Arto Mannermaa; H Sorvari; O Kosunen; Leo Paljärvi; Markku Ryynänen; PJ Riekkinen
Alzheimer pathology of patients carrying apolipoprotein E epsilon 4 allele.
Neurobiology of aging 1995;16(4):505-13.
1995: Maarit Lehtovirta; Mikko P Laakso; Hilkka Soininen; Seppo Helisalmi; Arto Mannermaa; Eeva-Liisa Helkala; Kaarina Partanen; Markku Ryynänen; Pauli Vainio; Päivi Hartikainen
Volumes of hippocampus, amygdala and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes.
Neuroscience 1995;67(1):65-72.
1995: Pertti Kirkinen; Markku Ryynänen
First-trimester manifestation of intrahepatic cholestasis of pregnancy and high fetoplacental hormone production in a triploid fetus. A case report.
The Journal of reproductive medicine 1995;40(6):471-3.
1995: O Kosunen; S Talasniemi; Maarit Lehtovirta; Outi Kopra; Seppo Helisalmi; Arto Mannermaa; Leo Paljärvi; Markku Ryynänen; PJ Riekkinen; Hilkka Soininen
Relation of coronary atherosclerosis and apolipoprotein E genotypes in Alzheimer patients.
Stroke; a journal of cerebral circulation 1995;26(5):743-8.
1995: Markku Ryynänen; Pertti Kirkinen; Arto Mannermaa; S Saarikoski
Carrier diagnosis of the fragile X syndrome--a challenge in antenatal clinics.
American journal of obstetrics and gynecology 1995;172(4 Pt 1):1236-9.
1995: Hilkka Soininen; O Kosunen; Seppo Helisalmi; Arto Mannermaa; Leo Paljärvi; S Talasniemi; Markku Ryynänen; PJ Riekkinen
A severe loss of choline acetyltransferase in the frontal cortex of Alzheimer patients carrying apolipoprotein epsilon 4 allele.
Neuroscience letters 1995;187(2):79-82.
1995: Maarit Lehtovirta; Seppo Helisalmi; Arto Mannermaa; Hilkka Soininen; Keijo Koivisto; Markku Ryynänen; PJ Riekkinen
Apolipoprotein E polymorphism and Alzheimer's disease in eastern Finland.
Neuroscience letters 1995;185(1):13-5.
1995: Hilkka Soininen; Kaarina Partanen; Asla Pitkänen; Merja Hallikainen; Tuomo Hänninen; Seppo Helisalmi; Arto Mannermaa; Markku Ryynänen; Keijo Koivisto; PJ Riekkinen
Decreased hippocampal volume asymmetry on MRIs in nondemented elderly subjects carrying the apolipoprotein E epsilon 4 allele.
Neurology 1995;45(2):391-2.
1994: Pertti Kirkinen; Markku Ryynänen; P Haring; H Torkkeli; L Pääkkönen; Anneli Martikainen
Prenatal activity of a fetus with early-onset, severe spinal muscular atrophy.
Prenatal diagnosis 1994;14(11):1074-6.
1994: Markku Ryynänen; L Pulkkinen; Pertti Kirkinen; S Saarikoski
Fragile-X syndrome in east Finland: molecular approach to genetic and prenatal diagnosis.
American journal of medical genetics 1994;51(4):463-5.
1993: I M Penttilä; Markku Ryynänen; Esa Hämäläinen; E Puhakainen; K Savolainen
Quality specifications for S-AFP and S-HCG-beta determinations for screening of fetal abnormalities.
Upsala journal of medical sciences 1993;98(3):375-80.
1991: Irma Järvelä; J Rapola; Leena Peltonen; L Puhakka; Jouni Vesa; P Ammälä; R Salonen; Markku Ryynänen; P Haring; A Mustonen
DNA-based prenatal diagnosis of the infantile form of neuronal ceroid lipofuscinosis (INCL, CLN1).
Prenatal diagnosis 1991;11(5):323-8.
1990: Markku Ryynänen; Anneli Martikainen; S Saarikoski
Antenatally diagnosed fetal hydronephrosis. Five year's follow up.
Journal of perinatal medicine 1990;18(4):313-6.
1990: I M Penttilä; E Puhakainen; Markku Ryynänen
Selecting a sensitive immunoradiometric method of maternal serum alphafetoprotein for prenatal screening of abnormalities in the fetus.
Upsala journal of medical sciences 1990;95(3):287-90.
1990: Markku Ryynänen; E Puhakainen; M Laakso; S Suonio; S Saarikoski
[Screening for Down syndrome in the fetus using maternal blood samples].
Duodecim; lääketieteellinen aikakauskirja 1990;106(21):1431-6.
1987: R H Lindenbaum; Markku Ryynänen; M Holmes-Siedle; E Puhakainen; J Jonasson; J Keenan
Trisomy 18 and maternal serum and amniotic fluid alpha-fetoprotein.
Prenatal diagnosis 1987;7(7):511-9.