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Ulpu Saarialho-Kere

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Laura Mäkitalo; Johanna Natunen; Mikko Pakarinen; Maija Piekkala; Risto Rintala; Ulpu Saarialho-Kere; Merja Ashorn; Riitta Karikoski; Antti Koivusalo; Kaija-Leena Kolho
Matrix metalloproteinases in the restorative proctocolectomy pouch of pediatric ulcerative colitis.
Terhi Savinko; Guoying Wang; Henrik Wolff; Piia Karisola; Antti Lauerma; Sari Lehtimäki; Maili Lehto; Sampsa Matikainen; Timo Reunala; Ulpu Saarialho-Kere; Harri Alenius
IL-33 and ST2 in atopic dermatitis: expression profiles and modulation by triggering factors.
Maarit Tanskanen; Liisa Myllykangas; Ulpu Saarialho-Kere; Anders Paetau
Matrix metalloproteinase-β19 expressed in cerebral amyloid angiopathy.

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2012: Laura Mäkitalo; Johanna Natunen; Mikko Pakarinen; Maija Piekkala; Risto Rintala; Ulpu Saarialho-Kere; Merja Ashorn; Riitta Karikoski; Antti Koivusalo; Kaija-Leena Kolho
Matrix metalloproteinases in the restorative proctocolectomy pouch of pediatric ulcerative colitis.
World journal of gastroenterology : WJG 2012;18(30):4028-36.
2012: Terhi Savinko; Guoying Wang; Henrik Wolff; Piia Karisola; Antti Lauerma; Sari Lehtimäki; Maili Lehto; Sampsa Matikainen; Timo Reunala; Ulpu Saarialho-Kere; Harri Alenius
IL-33 and ST2 in atopic dermatitis: expression profiles and modulation by triggering factors.
The Journal of investigative dermatology 2012;132(5):1392-400.
2011: Maarit Tanskanen; Liisa Myllykangas; Ulpu Saarialho-Kere; Anders Paetau
Matrix metalloproteinase-β19 expressed in cerebral amyloid angiopathy.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2011;18(1):3-9.
2010: Laura Mäkitalo; Kaija-Leena Kolho; Riitta Karikoski; Hannele Anthoni; Ulpu Saarialho-Kere
Expression profiles of matrix metalloproteinases and their inhibitors in colonic inflammation related to pediatric inflammatory bowel disease.
Scandinavian journal of gastroenterology 2010;45(7-8):862-71.
2010: Leena Latonen; Päivi M Järvinen; Sari Suomela; Henna M Moore; Ulpu Saarialho-Kere; Marikki Laiho
Ultraviolet B radiation regulates cysteine-rich protein 1 in human keratinocytes.
Photodermatology, photoimmunology & photomedicine 2010;26(2):70-7.
2010: Tiina M Järvinen; Anna Hellquist; Sari Koskenmies; Elisabet Einarsdottir; Lotta L E Koskinen; Leila Jeskanen; Linda Berglind; Jaana Panelius; Taina Hasan; Annamari Ranki; Juha Kere; Ulpu Saarialho-Kere
Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms are associated with discoid and subacute cutaneous lupus erythematosus.
Experimental dermatology 2010;19(2):123-31.
2010: Tiina M Järvinen; Anna Hellquist; Sari Koskenmies; Elisabet Einarsdottir; Jaana Panelius; Taina Hasan; Heikki Julkunen; Leonid Padyukov; Marika Kvarnström; Marie Wahren-Herlenius; Filippa Nyberg; Mauro D'Amato; Juha Kere; Ulpu Saarialho-Kere
Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus.
PloS one 2010;5(12):e14212.
2010: L Sundman; Ulpu Saarialho-Kere; Johanna Vendelin; Katri Lindfors; G Assadi; Katri Kaukinen; Mia Westerholm-Ormio; Erkki Savilahti; Markku Mäki; Harri Alenius; Mauro D'Amato; Ville Pulkkinen; Juha Kere; P Saavalainen
Neuropeptide S receptor 1 expression in the intestine and skin--putative role in peptide hormone secretion.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2010;22(1):79-87, e30.
2009: Sari Suomela; Virve Koljonen; Tiina Skoog; Heli Kukko; Tom Böhling; Ulpu Saarialho-Kere
Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma.
Virchows Archiv : an international journal of pathology 2009;455(6):495-503.
2009: Sonja Boyd; Susanna Virolainen; Jenita Pärssinen; Tiina Skoog; Max van Hogerlinden; Leena Latonen; Lauri E Kyllönen; Rune Toftgard; Ulpu Saarialho-Kere
MMP-10 (Stromelysin-2) and MMP-21 in human and murine squamous cell cancer.
Experimental dermatology 2009;18(12):1044-52.
2009: Laura Mäkitalo; Taina Sipponen; Päivi Kärkkäinen; Kaija-Leena Kolho; Ulpu Saarialho-Kere
Changes in matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression profile in Crohn's disease after immunosuppressive treatment correlate with histological score and calprotectin values.
International journal of colorectal disease 2009;24(10):1157-67.
2009: Tiina Kuivanen; Leila Jeskanen; Lauri E Kyllönen; Keiichi Isaka; Ulpu Saarialho-Kere
Matrix metalloproteinase-26 is present more frequently in squamous cell carcinomas of immunosuppressed compared with immunocompetent patients.
Journal of cutaneous pathology 2009;36(9):929-36.
2009: Antonio Di Sabatino; Ulpu Saarialho-Kere; Mark G Buckley; John N Gordon; Paolo Biancheri; Laura Rovedatti; Gino R Corazza; Thomas T MacDonald; Sylvia L F Pender
Stromelysin-1 and macrophage metalloelastase expression in the intestinal mucosa of Crohn's disease patients treated with infliximab.
European journal of gastroenterology & hepatology 2009;21(9):1049-55.
2009: Anna Hellquist; Tiina M Järvinen; Sari Koskenmies; Marco Zucchelli; Christina Orsmark-Pietras; Linda Berglind; Jaana Panelius; Taina Hasan; Heikki Julkunen; Mauro D'Amato; Ulpu Saarialho-Kere; Juha Kere
Evidence for genetic association and interaction between the TYK2 and IRF5 genes in systemic lupus erythematosus.
The Journal of rheumatology 2009;36(8):1631-8.
2009: Kati Kainu; Katja Kivinen; Marco Zucchelli; Sari Suomela; Juha Kere; Annica Inerot; Barbara S Baker; Anne V Powles; Lionel Fry; Lena Samuelsson; Ulpu Saarialho-Kere
Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families.
Experimental dermatology 2009;18(2):109-15.
2009: Anna Hellquist; Marco Zucchelli; Cecilia M Lindgren; Ulpu Saarialho-Kere; Tiina M Järvinen; Sari Koskenmies; Heikki Julkunen; Päivi Onkamo; Tiina Skoog; Jaana Panelius; Anne Räisänen-Sokolowski; Taina Hasan; Elisabeth Widen; Iva Gunnarson; Elisabet Svenungsson; Leonid Padyukov; Ghazaleh Assadi; Linda Berglind; Ville-Veikko Mäkelä; Katja Kivinen; Andrew Wong; Deborah S Cunningham Graham; Timothy J Vyse; Mauro D'Amato; Juha Kere
Identification of MAMDC1 as a candidate susceptibility gene for systemic lupus erythematosus (SLE).
PloS one 2009;4(12):e8037.
2009: Sari Suomela; Outi Elomaa; Tiina Skoog; Risto Ala-Aho; Leila Jeskanen; Jenita Pärssinen; Leena Latonen; Reidar Grénman; Juha Kere; Veli-Matti Kähäri; Ulpu Saarialho-Kere
CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.
PloS one 2009;4(6):e6030.
2009: Elisabet Einarsdottir; Lotta L E Koskinen; Emma Dukes; Kati Kainu; Sari Suomela; Maija Lappalainen; Fabiana Ziberna; Ilma R Korponay-Szabo; Kalle Kurppa; Katri Kaukinen; Róza Adány; Zsuzsa Pocsai; György Széles; Martti Färkkilä; Ulla Turunen; Leena Halme; Paulina Paavola-Sakki; Tarcisio Not; Serena Vatta; Alessandro Ventura; Robert Löfberg; Leif Torkvist; Francesca Bresso; Jonas Halfvarson; Markku Mäki; Kimmo Kontula; Ulpu Saarialho-Kere; Juha Kere; Mauro D'Amato; Päivi Saavalainen
IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease.
BMC medical genetics 2009;10():8.
2008: Sari Koskenmies; T M Järvinen; Päivi Onkamo; Jaana Panelius; U Tuovinen; T Hasan; Annamari Ranki; Ulpu Saarialho-Kere
Clinical and laboratory characteristics of Finnish lupus erythematosus patients with cutaneous manifestations.
Lupus 2008;17(4):337-47.
2008: Inkeri Tiala; Janica Wakkinen; Sari Suomela; Pauli Puolakkainen; Raija Tammi; Sofi Forsberg; Ola Rollman; Kati Kainu; Björn Rozell; Juha Kere; Ulpu Saarialho-Kere; Outi Elomaa
The PSORS1 locus gene CCHCR1 affects keratinocyte proliferation in transgenic mice.
Human molecular genetics 2008;17(7):1043-51.
2008: Sonja Boyd; Kalle Tolvanen; Susanna Virolainen; Tiina Kuivanen; Lauri Kyllönen; Ulpu Saarialho-Kere
Differential expression of stromal MMP-1, MMP-9 and TIMP-1 in basal cell carcinomas of immunosuppressed patients and controls.
Virchows Archiv : an international journal of pathology 2008;452(1):83-90.
2007: Ville Bister; Laura Mäkitalo; Leila Jeskanen; Ulpu Saarialho-Kere
Expression of MMP-9, MMP-10 and TNF-alpha and lack of epithelial MMP-1 and MMP-26 characterize pyoderma gangrenosum.
Journal of cutaneous pathology 2007;34(12):889-98.
2007: Ville Bister; Tiina Skoog; Susanna Virolainen; Tuula Kiviluoto; Pauli Puolakkainen; Ulpu Saarialho-Kere
Increased expression of matrix metalloproteinases-21 and -26 and TIMP-4 in pancreatic adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(11):1128-40.
2007: T M Järvinen; P Kanninen; Leila Jeskanen; Sari Koskenmies; J Panelius; T Hasan; Annamari Ranki; Ulpu Saarialho-Kere
Matrix metalloproteinases as mediators of tissue injury in different forms of cutaneous lupus erythematosus.
The British journal of dermatology 2007;157(5):970-80.
2007: Inkeri Tiala; Sari Suomela; Jari Huuhtanen; Janica Wakkinen; Maarit Hölttä-Vuori; Kati Kainu; Sirpa Ranta; Ursula Turpeinen; Esa Hämäläinen; Hong Jiao; Seija-Liisa Karvonen; Elina Ikonen; Juha Kere; Ulpu Saarialho-Kere; Outi Elomaa
The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes.
Journal of molecular medicine (Berlin, Germany) 2007;85(6):589-601.
2007: Anna Hellquist; Marco Zucchelli; Katja Kivinen; Ulpu Saarialho-Kere; Sari Koskenmies; Elisabeth Widen; Heikki Julkunen; Andrew Wong; Marja-Liisa Karjalainen-Lindsberg; Tiina Skoog; Johanna Vendelin; Deborah S Cunninghame-Graham; Timothy J Vyse; Juha Kere; Cecilia M Lindgren
The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus.
Journal of medical genetics 2007;44(5):314-21.
2007: Harri Sihto; Olli Tynninen; Ralf Bützow; Ulpu Saarialho-Kere; Heikki Joensuu
Endothelial cell KIT expression in human tumours.
The Journal of pathology 2007;211(4):481-8.
2007: Christina Orsmark; Tiina Skoog; Leila Jeskanen; Juha Kere; Ulpu Saarialho-Kere
Expression of allograft inflammatory factor-1 in inflammatory skin disorders.
Acta dermato-venereologica 2007;87(3):223-7.
2007: Sari Suomela; Kati Kainu; Päivi Onkamo; Inkeri Tiala; Johan Himberg; Lotta Koskinen; Erna Snellman; Seija-Liisa Karvonen; Juha T Karvonen; Tutta Uurasmaa; Timo Reunala; Kristiina Kivikäs; Christer T Jansén; Päivi Holopainen; Outi Elomaa; Juha Kere; Ulpu Saarialho-Kere
Clinical associations of the risk alleles of HLA-Cw6 and CCHCR1*WWCC in psoriasis.
Acta dermato-venereologica 2007;87(2):127-34.
2007: Emma Pirilä; Jarkko T Korpi; Timo Korkiamäki; Tiina Jahkola; Ana Gutierrez-Fernandez; Carlos Lopez-Otin; Ulpu Saarialho-Kere; Tuula Salo; Timo Sorsa
Collagenase-2 (MMP-8) and matrilysin-2 (MMP-26) expression in human wounds of different etiologies.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2007;15(1):47-57.
2006: Tiina Skoog; Katja Ahokas; Christina Orsmark; Leila Jeskanen; Keiichi Isaka; Ulpu Saarialho-Kere
MMP-21 is expressed by macrophages and fibroblasts in vivo and in culture.
Experimental dermatology 2006;15(10):775-83.
2006: Johanna Vendelin; Sara Bruce; Päivi Holopainen; Ville Pulkkinen; Paula Rytilä; Asta Pirskanen; Marko Rehn; Tarja Laitinen; Lauri A Laitinen; Tari Haahtela; Ulpu Saarialho-Kere; Annika Laitinen; Juha Kere
Downstream target genes of the neuropeptide S-NPSR1 pathway.
Human molecular genetics 2006;15(19):2923-35.
2006: Tiina Kuivanen; Leila Jeskanen; Lauri E Kyllönen; Ulla Impola; Ulpu Saarialho-Kere
Transformation-specific matrix metalloproteinases, MMP-7 and MMP-13, are present in epithelial cells of keratoacanthomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(9):1203-12.
2006: Sonja Hahtola; Soile Tuomela; Laura L Elo; Tiina Häkkinen; Leena Karenko; Boguslaw Nedoszytko; Hannele Heikkilä; Ulpu Saarialho-Kere; Jadwiga Roszkiewicz; Tero Aittokallio; Riitta Lahesmaa; Annamari Ranki
Th1 response and cytotoxicity genes are down-regulated in cutaneous T-cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(16):4812-21.
2006: Sofi Forsberg; Ulpu Saarialho-Kere; Ola Rollman
Comparison of growth-inhibitory agents by fluorescence imaging of human skin re-epithelialization in vitro.
Acta dermato-venereologica 2006;86(4):292-9.
2006: Katja Ahokas; Marja-Liisa Karjalainen-Lindsberg; Eero I T Sihvo; Keiichi Isaka; Jarmo Salo; Ulpu Saarialho-Kere
Matrix metalloproteinases 21 and 26 are differentially expressed in esophageal squamous cell cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2006;27(3):133-41.
2005: Ville Bister; Kaija-Leena Kolho; Riitta Karikoski; Mia Westerholm-Ormio; Erkki Savilahti; Ulpu Saarialho-Kere
Metalloelastase (MMP-12) is upregulated in the gut of pediatric patients with potential celiac disease and in type 1 diabetes.
Scandinavian journal of gastroenterology 2005;40(12):1413-22.
2005: Tiina Kuivanen; Katja Ahokas; Susanna Virolainen; Tiina Jahkola; Erkki Hölttä; Olli Saksela; Ulpu Saarialho-Kere
MMP-21 is upregulated at early stages of melanoma progression but disappears with more aggressive phenotype.
Virchows Archiv : an international journal of pathology 2005;447(6):954-60.
2005: Ulla Impola; Leila Jeskanen; LS Ravanti; S Syrjänen; BT Baldursson; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Expression of matrix metalloproteinase (MMP)-7 and MMP-13 and loss of MMP-19 and p16 are associated with malignant progression in chronic wounds.
The British journal of dermatology 2005;152(4):720-6.
2005: Katja Ahokas; Tiina Skoog; Sari Suomela; Leila Jeskanen; Ulla Impola; Keiichi Isaka; Ulpu Saarialho-Kere
Matrilysin-2 (matrix metalloproteinase-26) is upregulated in keratinocytes during wound repair and early skin carcinogenesis.
The Journal of investigative dermatology 2005;124(4):849-56.
2005: Kazuhiko Nakabayashi; Daniela Amann; Yan Ren; Ulpu Saarialho-Kere; Nili Avidan; Simone Gentles; Jeffrey R MacDonald; Erik G Puffenberger; Angela M Christiano; Amalia Martinez-Mir; Julio C Salas-Alanis; Renata Rizzo; Esther Vamos; Anja Raams; Clifford M Les; Eric Seboun; Nicolaas G J Jaspers; Jacques Beckmann; Charles E Jackson; Stephen W Scherer
Identification of C7orf11 (TTDN1) gene mutations and genetic heterogeneity in nonphotosensitive trichothiodystrophy.
American journal of human genetics 2005;76(3):510-6.
2005: Ville Bister; Mikko T Salmela; Päivi Heikkilä; Annaleena Anttila; Risto J Rintala; Keiichi Isaka; Sture Andersson; Ulpu Saarialho-Kere
Matrilysins-1 and -2 (MMP-7 and -26) and metalloelastase (MMP-12), unlike MMP-19, are up-regulated in necrotizing enterocolitis.
Journal of pediatric gastroenterology and nutrition 2005;40(1):60-6.
2004: M Weckroth; Antti Vaheri; Susanna Virolainen; Ulpu Saarialho-Kere; Tiina Jahkola; Vappu Sirén
Epithelial tissue-type plasminogen activator expression, unlike that of urokinase, its receptor, and plasminogen activator inhibitor-1, is increased in chronic venous ulcers.
The British journal of dermatology 2004;151(6):1189-96.
2004: Mikko T Salmela; Sylvia L F Pender; Marja-Liisa Karjalainen-Lindsberg; Pauli Puolakkainen; Thomas T MacDonald; Ulpu Saarialho-Kere
Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing.
Scandinavian journal of gastroenterology 2004;39(11):1095-104.
2004: Tiina Kuivanen; Maarit Tanskanen; Tiina Jahkola; Ulla Impola; Sirpa Asko-Seljavaara; Ulpu Saarialho-Kere
Matrilysin-1 (MMP-7) and MMP-19 are expressed by Paget's cells in extramammary Paget's disease.
Journal of cutaneous pathology 2004;31(7):483-91.
2004: Outi Elomaa; Inkeri Majuri; Sari Suomela; Kati Asumalahti; Hong Jiao; Zahra Mirzaei; Bjorn Rozell; Karin Dahlman-Wright; Johanna Pispa; Juha Kere; Ulpu Saarialho-Kere
Transgenic mouse models support HCR as an effector gene in the PSORS1 locus.
Human molecular genetics 2004;13(15):1551-61.
2004: Ulpu Saarialho-Kere
The gut-skin axis.
Journal of pediatric gastroenterology and nutrition 2004;39 Suppl 3():S734-5.
2004: Ville Bister; Mikko T Salmela; Marja-Liisa Karjalainen-Lindsberg; J Uria; Jouko Lohi; Pauli Puolakkainen; Carlos Lopez-Otin; Ulpu Saarialho-Kere
Differential expression of three matrix metalloproteinases, MMP-19, MMP-26, and MMP-28, in normal and inflamed intestine and colon cancer.
Digestive diseases and sciences 2004;49(4):653-61.
2004: Sari Suomela; Li Cao; Anne M Bowcock; Ulpu Saarialho-Kere
Interferon alpha-inducible protein 27 (IFI27) is upregulated in psoriatic skin and certain epithelial cancers.
The Journal of investigative dermatology 2004;122(3):717-21.
2004: Lari Häkkinen; Leeni Koivisto; Humphrey Gardner; Ulpu Saarialho-Kere; Joseph M Carroll; Merja Lakso; Heikki Rauvala; Matti Laato; Jyrki Heino; Hannu Larjava
Increased expression of beta6-integrin in skin leads to spontaneous development of chronic wounds.
The American journal of pathology 2004;164(1):229-42.
2004: Ulla Impola; Veli-Jukka Uitto; Jarkko Hietanen; Lari Hakkinen; L Zhang; Hannu Larjava; Keiichi Isaka; Ulpu Saarialho-Kere
Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer.
The Journal of pathology 2004;202(1):14-22.
2003: Katja Ahokas; Jouko Lohi; Sara A Illman; Elena Llano; Outi Elomaa; Ulla Impola; Marja-Liisa Karjalainen-Lindsberg; Ulpu Saarialho-Kere
Matrix metalloproteinase-21 is expressed epithelially during development and in cancer and is up-regulated by transforming growth factor-beta1 in keratinocytes.
Laboratory investigation; a journal of technical methods and pathology 2003;83(12):1887-99.
2003: Sari Suomela; Outi Elomaa; Kati Asumalahti; Arja-Leena Kariniemi; Seija-Liisa Karvonen; Juha Peltonen; Juha Kere; Ulpu Saarialho-Kere
HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes.
The Journal of investigative dermatology 2003;121(6):1360-4.
2003: Julie T Daniels; Gerd Geerling; Robert Andrew Alexander; Gillian Murphy; Peng Khaw; Ulpu Saarialho-Kere
Temporal and spatial expression of matrix metalloproteinases during wound healing of human corneal tissue.
Experimental eye research 2003;77(6):653-64.
2003: Niina Hieta; Ulla Impola; Carlos López-Otín; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Matrix metalloproteinase-19 expression in dermal wounds and by fibroblasts in culture.
The Journal of investigative dermatology 2003;121(5):997-1004.
2003: Kati Asumalahti; Tarja Laitinen; Päivi Lahermo; Sari Suomela; Raija Itkonen-Vatjus; Christer Jansen; Juha T Karvonen; Seija-Liisa Karvonen; Timo Reunala; Erna Snellman; Tutta Uurasmaa; Ulpu Saarialho-Kere; Juha Kere
Psoriasis susceptibility locus on 18p revealed by genome scan in Finnish families not associated with PSORS1.
The Journal of investigative dermatology 2003;121(4):735-40.
2003: Ulla Impola; Maria Antonietta Cuccuru; Maria Vittoria Masala; Leila Jeskanen; Francesca Cottoni; Ulpu Saarialho-Kere
Preliminary communication: matrix metalloproteinases in Kaposi's sarcoma.
The British journal of dermatology 2003;149(4):905-7.
2003: Erja Kerkelä; Ulpu Saarialho-Kere
Matrix metalloproteinases in tumor progression: focus on basal and squamous cell skin cancer.
Experimental dermatology 2003;12(2):109-25.
2003: Kati Asumalahti; Mahreen Ameen; Sari Suomela; Eva Hagforsen; Gerd Michaëlsson; Julie Evans; Margo Munro; Colin Veal; Michael Allen; Joyce Leman; A David Burden; Brian Kirby; Maureen Connolly; Christopher E M Griffiths; Richard C Trembath; Juha Kere; Ulpu Saarialho-Kere; J N W N Barker
Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantar pustulosis.
The Journal of investigative dermatology 2003;120(4):627-32.
2003: Julie T Daniels; G Astrid Limb; Ulpu Saarialho-Kere; Gillian Murphy; Peng Khaw
Human corneal epithelial cells require MMP-1 for HGF-mediated migration on collagen I.
Investigative ophthalmology & visual science 2003;44(3):1048-55.
2003: Ulla Impola; Mervi J Toriseva; Sari Suomela; Leila Jeskanen; Niina Hieta; Tiina Jahkola; Reidar Grenman; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Matrix metalloproteinase-19 is expressed by proliferating epithelium but disappears with neoplastic dedifferentiation.
International journal of cancer. Journal international du cancer 2003;103(6):709-16.
2003: Mikko T Salmela; Marja-Liisa Karjalainen-Lindsberg; Leila Jeskanen; Ulpu Saarialho-Kere
Overexpression of tissue inhibitor of metalloproteinases-3 in intestinal and cutaneous lesions of graft-versus-host disease.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2003;16(2):108-14.
2003: Kati Asumalahti; Ulpu Saarialho-Kere; Juha Kere
[The pathogenesis of psoriasis--investigating the genetics of a multifactorial disease].
Duodecim; lääketieteellinen aikakauskirja 2003;119(16):1517-22.
2003: Sari Suomela; Arja-Leena Kariniemi; Ulla Impola; Seija-Liisa Karvonen; Erna Snellman; Tutta Uurasmaa; Juha Peltonen; Ulpu Saarialho-Kere
Matrix metalloproteinase-19 is expressed by keratinocytes in psoriasis.
Acta dermato-venereologica 2003;83(2):108-14.
2002: Katja Ahokas; Jouko Lohi; Hannes Lohi; Outi Elomaa; Marja-Liisa Karjalainen-Lindsberg; Juha Kere; Ulpu Saarialho-Kere
Matrix metalloproteinase-21, the human orthologue for XMMP, is expressed during fetal development and in cancer.
Gene 2002;301(1-2):31-41.
2002: Erja Kerkelä; Risto Ala-Aho; Pekka Klemi; Seija Grénman; Steven D Shapiro; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.
The Journal of pathology 2002;198(2):258-69.
2002: Mikko T Salmela; Thomas T MacDonald; D Black; B Irvine; T Zhuma; Ulpu Saarialho-Kere; Sylvia L F Pender
Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation.
Gut 2002;51(4):540-7.
2002: Ulpu Saarialho-Kere; Erja Kerkelä; Tiina Jahkola; Sari Suomela; Jorma Keski-Oja; Jouko Lohi
Epilysin (MMP-28) expression is associated with cell proliferation during epithelial repair.
The Journal of investigative dermatology 2002;119(1):14-21.
2002: Matti Ahonen; Risto Ala-Aho; Andrew H Baker; Sarah George; Reidar Grénman; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Antitumor activity and bystander effect of adenovirally delivered tissue inhibitor of metalloproteinases-3.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(6):705-15.
2002: Johanna Laurikkala; Johanna Pispa; Han-Sung Jung; Pekka Nieminen; Marja L Mikkola; Xiuping Wang; Ulpu Saarialho-Kere; Juan Galceran; Rudolf Grosschedl; Irma Thesleff
Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar.
Development (Cambridge, England) 2002;129(10):2541-53.
2002: Hannes Lohi; Minna Kujala; Siru Makela; Eero Lehtonen; Marjo Kestila; Ulpu Saarialho-Kere; Daniel Markovich; Juha Kere
Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9.
The Journal of biological chemistry 2002;277(16):14246-54.
2002: Veli-Jukka Uitto; Jukka I Salonen; James D Firth; H Jousimies-Somer; Ulpu Saarialho-Kere
Matrilysin (matrix metalloproteinase-7) expression in human junctional epithelium.
Journal of dental research 2002;81(4):241-6.
2002: Ursula Mirastschijski; Ulla Impola; Tiina Jahkola; Tonny Karlsmark; Magnus Ågren; Ulpu Saarialho-Kere
Ectopic localization of matrix metalloproteinase-9 in chronic cutaneous wounds.
Human pathology 2002;33(3):355-64.
2002: Kati Asumalahti; Colin Veal; Tarja Laitinen; Sari Suomela; Michael Allen; Outi Elomaa; Michael Moser; Rafael de Cid; Samuli Ripatti; Igor Vorechovsky; Jan A Marcusson; Hidemi Nakagawa; Conxi Lazaro; Xavier Estivill; Francesca Capon; Giuseppe Novelli; Ulpu Saarialho-Kere; Jonathan Barker; Richard C Trembath; Juha Kere
Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus.
Human molecular genetics 2002;11(5):589-97.
2002: Ursula Mirastschijski; Ulla Impola; Morten A Karsdal; Ulpu Saarialho-Kere; Magnus Ågren
Matrix metalloproteinase inhibitor BB-3103 unlike the serine proteinase inhibitor aprotinin abrogates epidermal healing of human skin wounds ex vivo.
The Journal of investigative dermatology 2002;118(1):55-64.
2001: Erja Kerkelä; T Böhling; R Herva; J A Uria; Ulpu Saarialho-Kere
Human macrophage metalloelastase (MMP-12) expression is induced in chondrocytes during fetal development and malignant transformation.
Bone 2001;29(5):487-93.
2001: Magnus Ågren; Ursula Mirastschijski; Tonny Karlsmark; Ulpu Saarialho-Kere
Topical synthetic inhibitor of matrix metalloproteinases delays epidermal regeneration of human wounds.
Experimental dermatology 2001;10(5):337-48.
2001: E Virolainen; Katri Niemi; Agneta Gånemo; Juha Kere; Anders Vahlquist; Ulpu Saarialho-Kere
Ultrastructural features resembling those of harlequin ichthyosis in patients with severe congenital ichthyosiform erythroderma.
The British journal of dermatology 2001;145(3):480-3.
2001: Mikko T Salmela; Marja-Liisa Karjalainen-Lindsberg; Pauli Puolakkainen; Ulpu Saarialho-Kere
Upregulation and differential expression of matrilysin (MMP-7) and metalloelastase (MMP-12) and their inhibitors TIMP-1 and TIMP-3 in Barrett's oesophageal adenocarcinoma.
British journal of cancer 2001;85(3):383-92.
2001: S Haila; Johanna Hästbacka; T Böhling; Marja-Liisa Karjalainen-Lindsberg; Juha Kere; Ulpu Saarialho-Kere
SLC26A2 (diastrophic dysplasia sulfate transporter) is expressed in developing and mature cartilage but also in other tissues and cell types.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(8):973-82.
2001: Sari Suomela; Arja-Leena Kariniemi; Erna Snellman; Ulpu Saarialho-Kere
Metalloelastase (MMP-12) and 92-kDa gelatinase (MMP-9) as well as their inhibitors, TIMP-1 and -3, are expressed in psoriatic lesions.
Experimental dermatology 2001;10(3):175-83.
2001: Outi Elomaa; K Pulkkinen; Ulf Hannelius; Marja L Mikkola; Ulpu Saarialho-Kere; Juha Kere
Ectodysplasin is released by proteolytic shedding and binds to the EDAR protein.
Human molecular genetics 2001;10(9):953-62.
2001: Mikko T Salmela; Sylvia L F Pender; Timo Reunala; T MacDonald; Ulpu Saarialho-Kere
Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis.
Gut 2001;48(4):496-502.
2001: Erja Kerkelä; Risto Ala-Aho; Jouko Lohi; Reidar Grénman; V M-Kähäri; Ulpu Saarialho-Kere
Differential patterns of stromelysin-2 (MMP-10) and MT1-MMP (MMP-14) expression in epithelial skin cancers.
British journal of cancer 2001;84(5):659-69.
2000: Sylvia L F Pender; Mikko T Salmela; Giovanni Monteleone; D Schnapp; C McKenzie; J Spencer; S Fong; Ulpu Saarialho-Kere; Thomas T MacDonald
Ligation of alpha4ss1 integrin on human intestinal mucosal mesenchymal cells selectively Up-regulates membrane type-1 matrix metalloproteinase and confers a migratory phenotype.
The American journal of pathology 2000;157(6):1955-62.
2000: Hannes Lohi; Minna Kujala; Erja Kerkelä; Ulpu Saarialho-Kere; Marjo Kestilä; Juha Kere
Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger.
Genomics 2000;70(1):102-12.
2000: O Rechardt; Outi Elomaa; MO Vaalamo; Kimmo Pääkkönen; Tiina Jahkola; Johanna Höök-Nikanne; R M Hembry; Lari Häkkinen; Juha Kere; Ulpu Saarialho-Kere
Stromelysin-2 is upregulated during normal wound repair and is induced by cytokines.
The Journal of investigative dermatology 2000;115(5):778-87.
2000: Kati Asumalahti; Tarja Laitinen; R Itkonen-Vatjus; Marja-Liisa Lokki; Sari Suomela; Erna Snellman; Ulpu Saarialho-Kere; Juha Kere
A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele.
Human molecular genetics 2000;9(10):1533-42.
2000: Erja Kerkelä; Risto Ala-Aho; Leila Jeskanen; O Rechardt; Reidar Grénman; Steven D Shapiro; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
The Journal of investigative dermatology 2000;114(6):1113-9.
2000: S Haila; Ulpu Saarialho-Kere; Marja-Liisa Karjalainen-Lindsberg; Hannes Lohi; Karri Airola; Christer Holmberg; Johanna Hästbacka; Juha Kere; Pia Höglund
The congenital chloride diarrhea gene is expressed in seminal vesicle, sweat gland, inflammatory colon epithelium, and in some dysplastic colon cells.
Histochemistry and cell biology 2000;113(4):279-86.
1999: LS Ravanti; Lari Häkkinen; Hannu Larjava; Ulpu Saarialho-Kere; Marco Foschi; Jiahuai Han; Veli-Matti Kähäri
Transforming growth factor-beta induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen-activated protein kinase.
The Journal of biological chemistry 1999;274(52):37292-300.
1999: Ulpu Saarialho-Kere; Erja Kerkelä; Leila Jeskanen; T Hasan; R Pierce; Barry Starcher; R Raudasoja; Annamari Ranki; Aarne Oikarinen; MO Vaalamo
Accumulation of matrilysin (MMP-7) and macrophage metalloelastase (MMP-12) in actinic damage.
The Journal of investigative dermatology 1999;113(4):664-72.
1999: E Laiho; Katri Niemi; Jaakko Ignatius; Juha Kere; Aarno Palotie; Ulpu Saarialho-Kere
Clinical and morphological correlations for transglutaminase 1 gene mutations in autosomal recessive congenital ichthyosis.
European journal of human genetics : EJHG 1999;7(6):625-32.
1999: MO Vaalamo; Tomi Leivo; Ulpu Saarialho-Kere
Differential expression of tissue inhibitors of metalloproteinases (TIMP-1, -2, -3, and -4) in normal and aberrant wound healing.
Human pathology 1999;30(7):795-802.
1999: Karri Airola; T Karonen; MO Vaalamo; Kaisa Lehti; Jouko Lohi; Arja-Leena Kariniemi; Jorma Keski-Oja; Ulpu Saarialho-Kere
Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomas.
British journal of cancer 1999;80(5-6):733-43.
1999: MO Vaalamo; Arja-Leena Kariniemi; Steven D Shapiro; Ulpu Saarialho-Kere
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
The Journal of investigative dermatology 1999;112(4):499-505.
1999: Veli-Matti Kähäri; Ulpu Saarialho-Kere
Matrix metalloproteinases and their inhibitors in tumour growth and invasion.
Annals of medicine 1999;31(1):34-45.
1999: Nina Johansson; MO Vaalamo; Seija Grénman; Sakari Hietanen; Pekka Klemi; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas.
The American journal of pathology 1999;154(2):469-80.
1998: O Montonen; S Ezer; Johanna Laurikkala; Marja-Liisa Karjalainen-Lindsberg; Irma Thesleff; Juha Kere; Ulpu Saarialho-Kere
Expression of the anhidrotic ectodermal dysplasia gene is reduced in skin cancer coinciding with reduced E-cadherin.
Experimental dermatology 1998;7(4):168-74.
1998: Ulpu Saarialho-Kere
Patterns of matrix metalloproteinase and TIMP expression in chronic ulcers.
Archives of dermatological research 1998;290 Suppl():S47-54.
1998: Veli-Jukka Uitto; Karri Airola; MO Vaalamo; Nina Johansson; Edward E Putnins; James D Firth; J Salonen; Carlos López-Otín; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Collagenase-3 (matrix metalloproteinase-13) expression is induced in oral mucosal epithelium during chronic inflammation.
The American journal of pathology 1998;152(6):1489-99.
1998: MO Vaalamo; Marja-Liisa Karjalainen-Lindsberg; Pauli Puolakkainen; Juha Kere; Ulpu Saarialho-Kere
Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations.
The American journal of pathology 1998;152(4):1005-14.
1998: Leena Mattila; Karri Airola; Matti Ahonen; Marja Hietarinta; C Black; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Activation of tissue inhibitor of metalloproteinases-3 (TIMP-3) mRNA expression in scleroderma skin fibroblasts.
The Journal of investigative dermatology 1998;110(4):416-21.
1998: Karri Airola; Matti Ahonen; Nina Johansson; P Heikkilä; Juha Kere; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Human TIMP-3 is expressed during fetal development, hair growth cycle, and cancer progression.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(4):437-47.
1998: O Montonen; S Ezer; Ulpu Saarialho-Kere; Riitta Herva; Marja-Liisa Karjalainen-Lindsberg; I Kaitila; David Schlessinger; Anand K Srivastava; Irma Thesleff; Juha Kere
The gene defective in anhidrotic ectodermal dysplasia is expressed in the developing epithelium, neuroectoderm, thymus, and bone.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(3):281-9.
1998: Veli-Matti Kähäri; Nina Johansson; Reidar Grénman; Karri Airola; Ulpu Saarialho-Kere
Expression of collagenase-3 (MMP-13) by tumor cells in squamous cell carcinomas of the head and neck.
Advances in experimental medicine and biology 1998;451():63-8.
1997: Veli-Matti Kähäri; Ulpu Saarialho-Kere
Matrix metalloproteinases in skin.
Experimental dermatology 1997;6(5):199-213.
1997: E Laiho; Jaakko Ignatius; H Mikkola; Vivien C Yee; David C Teller; Katri Niemi; Ulpu Saarialho-Kere; Juha Kere; Aarno Palotie
Transglutaminase 1 mutations in autosomal recessive congenital ichthyosis: private and recurrent mutations in an isolated population.
American journal of human genetics 1997;61(3):529-38.
1997: Nina Johansson; Karri Airola; Reidar Grénman; Arja-Leena Kariniemi; Ulpu Saarialho-Kere; Veli-Matti Kähäri
Expression of collagenase-3 (matrix metalloproteinase-13) in squamous cell carcinomas of the head and neck.
The American journal of pathology 1997;151(2):499-508.
1997: Karri Airola; Nina Johansson; Arja-Leena Kariniemi; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Human collagenase-3 is expressed in malignant squamous epithelium of the skin.
The Journal of investigative dermatology 1997;109(2):225-31.
1997: MO Vaalamo; Leena Mattila; Nina Johansson; Arja-Leena Kariniemi; Marja-Liisa Karjalainen-Lindsberg; Veli-Matti Kähäri; Ulpu Saarialho-Kere
Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds.
The Journal of investigative dermatology 1997;109(1):96-101.
1997: Nina Johansson; Ulpu Saarialho-Kere; Karri Airola; R Herva; Liisa Nissinen; Jukka Westermarck; Eero Vuorio; Jyrki Heino; Veli-Matti Kähäri
Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;208(3):387-97.
1997: Karri Airola; Timo Reunala; S Salo; Ulpu Saarialho-Kere
Urokinase plasminogen activator is expressed by basal keratinocytes before interstitial collagenase, stromelysin-1, and laminin-5 in experimentally induced dermatitis herpetiformis lesions.
The Journal of investigative dermatology 1997;108(1):7-11.
1996: Pia Höglund; S Haila; J Socha; L Tomaszewski; Ulpu Saarialho-Kere; Marja-Liisa Karjalainen-Lindsberg; Karri Airola; Christer Holmberg; Albert de La Chapelle; Juha Kere
Mutations of the Down-regulated in adenoma (DRA) gene cause congenital chloride diarrhoea.
Nature genetics 1996;14(3):316-9.
1996: Juha Kere; Anand K Srivastava; O Montonen; Jonathan (Jon) Zonana; N Thomas; Betsy M Ferguson; F Munoz; D Morgan; A Clarke; P Baybayan; E Y Chen; S Ezer; Ulpu Saarialho-Kere; Albert de La Chapelle; David Schlessinger
X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein.
Nature genetics 1996;13(4):409-16.
1996: MO Vaalamo; M Weckroth; P Puolakkainen; Juha Kere; P Saarinen; J Lauharanta; Ulpu Saarialho-Kere
Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds.
The British journal of dermatology 1996;135(1):52-9.
1996: Ulpu Saarialho-Kere; MO Vaalamo; P Puolakkainen; Karri Airola; W C Parks; Marja-Liisa Karjalainen-Lindsberg
Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers.
The American journal of pathology 1996;148(2):519-26.
1996: Anand K Srivastava; O Montonen; Ulpu Saarialho-Kere; E Chen; P Baybayan; Johanna Pispa; J Limon; David Schlessinger; Juha Kere
Fine mapping of the EDA gene: a translocation breakpoint is associated with a CpG island that is transcribed.
American journal of human genetics 1996;58(1):126-32.
1995: Karri Airola; MO Vaalamo; Timo Reunala; Ulpu Saarialho-Kere
Enhanced expression of interstitial collagenase, stromelysin-1, and urokinase plasminogen activator in lesions of dermatitis herpetiformis.
The Journal of investigative dermatology 1995;105(2):184-9.
1995: Ulpu Saarialho-Kere; MO Vaalamo; Karri Airola; Katri Niemi; A I Oikarinen; W C Parks
Interstitial collagenase is expressed by keratinocytes that are actively involved in reepithelialization in blistering skin disease.
The Journal of investigative dermatology 1995;104(6):982-8.
1989: Ulpu Saarialho-Kere; Marco Mattila; Timo Seppälä
Psychomotor, respiratory and neuroendocrinological effects of a mu-opioid receptor agonist (oxycodone) in healthy volunteers.
Pharmacology & toxicology 1989;65(4):252-7.
1988: Ulpu Saarialho-Kere; Heikki Julkunen; Marco Mattila; Timo Seppälä
Psychomotor performance of patients with rheumatoid arthritis: cross-over comparison of dextropropoxyphene, dextropropoxyphene plus amitriptyline, indomethacin, and placebo.
Pharmacology & toxicology 1988;63(4):286-92.
1988: Marco Mattila; Ulpu Saarialho-Kere; M Mattila
Acute effects of sertraline, amitriptyline, and placebo on the psychomotor performance of healthy subjects over 50 years of age.
The Journal of clinical psychiatry 1988;49 Suppl():52-8.
1988: Ulpu Saarialho-Kere
Psychomotor, respiratory and neuroendocrinological effects of nalbuphine and haloperidol, alone and in combination, in healthy subjects.
British journal of clinical pharmacology 1988;26(1):79-87.
1988: Ulpu Saarialho-Kere; Marco Mattila; Timo Seppälä
Parenteral pentazocine: effects on psychomotor skills and respiration, and interactions with amitriptyline.
European journal of clinical pharmacology 1988;35(5):483-9.
1987: Ulpu Saarialho-Kere; Marco Mattila; M Paloheimo; Timo Seppälä
Psychomotor, respiratory and neuroendocrinological effects of buprenorphine and amitriptyline in healthy volunteers.
European journal of clinical pharmacology 1987;33(2):139-46.