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Ulpu Saarialho-Kere
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35
Kere, Juha
19
Kähäri, Veli-Matti
18
Suomela, Sari
16
Karjalainen-Lindsberg, Marja-Liisa
14
Airola, Karri
14
Jeskanen, Leila
13
Vaalamo, MO
12
Impola, Ulla
11
Elomaa, Outi
8
Jahkola, Tiina
8
Johansson, Nina
8
Kariniemi, Arja-Leena
8
Kerkelä, Erja
8
Salmela, Mikko
7
Asumalahti, Kati
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All Publications
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2009: Mäkitalo Laura; Sipponen Taina; Kärkkäinen Päivi; Kolho Kaija-Leena; Saarialho-Kere Ulpu
Changes in matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression profile in Crohn's disease after immunosuppressive treatment correlate with histological score and calprotectin values.
International journal of colorectal disease 2009;24(10):1157-67.
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2009: Kuivanen Tiina; Jeskanen Leila; Kyllönen Lauri; Isaka Keiichi; Saarialho-Kere Ulpu
Matrix metalloproteinase-26 is present more frequently in squamous cell carcinomas of immunosuppressed compared with immunocompetent patients.
Journal of cutaneous pathology 2009;36(9):929-36.
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2009: Di Sabatino Antonio; Saarialho-Kere Ulpu; Buckley Mark G; Gordon John N; Biancheri Paolo; Rovedatti Laura; Corazza Gino R; Macdonald Thomas T; Pender Sylvia L F
Stromelysin-1 and macrophage metalloelastase expression in the intestinal mucosa of Crohn's disease patients treated with infliximab.
European journal of gastroenterology & hepatology 2009;21(9):1049-55.
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2009: Hellquist Anna; Järvinen Tiina M; Koskenmies Sari; Zucchelli Marco; Orsmark-Pietras Christina; Berglind Linda; Panelius Jaana; Hasan Taina; Julkunen Heikki; D'Amato Mauro; Saarialho-Kere Ulpu; Kere Juha
Evidence for genetic association and interaction between the TYK2 and IRF5 genes in systemic lupus erythematosus.
The Journal of rheumatology 2009;36(8):1631-8.
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2009: Kainu Kati; Kivinen Katja; Zucchelli Marco; Suomela Sari; Kere Juha; Inerot Annica; Baker Barbara S; Powles Anne V; Fry Lionel; Samuelsson Lena; Saarialho-Kere Ulpu
Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families.
Experimental dermatology 2009;18(2):109-15.
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2009: Suomela Sari; Elomaa Outi; Skoog Tiina; Ala-aho Risto; Jeskanen Leila; Pärssinen Jenita; Latonen Leena; Grénman Reidar; Kere Juha; Kähäri Veli-Matti; Saarialho-Kere Ulpu
CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.
PloS one 2009;4(6):e6030.
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2009: Einarsdottir Elisabet; Koskinen Lotta L E; Dukes Emma; Kainu Kati; Suomela Sari; Lappalainen Maarit; Ziberna Fabiana; Korponay-Szabo Ilma R; Kurppa Kalle; Kaukinen Katri; Adány Róza; Pocsai Zsuzsa; Széles György; Färkkilä Martti; Turunen Ulla; Halme Leena; Paavola-Sakki Paulina; Not Tarcisio; Vatta Serena; Ventura Alessandro; Löfberg Robert; Torkvist Leif; Bresso Francesca; Halfvarson Jonas; Mäki Markku; Kontula Kimmo; Saarialho-Kere Ulpu; Kere Juha; D'Amato Mauro; Saavalainen Päivi
IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease.
BMC medical genetics 2009;10():8.
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2008: Tiala Inkeri; Wakkinen Janica; Suomela Sari; Puolakkainen Pauli; Tammi Raija; Forsberg Sofi; Rollman Ola; Kainu Kati; Rozell Björn; Kere Juha; Saarialho-Kere Ulpu; Elomaa Outi
The PSORS1 locus gene CCHCR1 affects keratinocyte proliferation in transgenic mice.
Human molecular genetics 2008;17(7):1043-51.
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2008: Boyd Sonja; Tolvanen Kalle; Virolainen Susanna; Kuivanen Tiina; Kyllönen Lauri; Saarialho-Kere Ulpu
Differential expression of stromal MMP-1, MMP-9 and TIMP-1 in basal cell carcinomas of immunosuppressed patients and controls.
Virchows Archiv : an international journal of pathology 2008;452(1):83-90.
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2008: Koskenmies S; Järvinen T M; Onkamo P; Panelius J; Tuovinen U; Hasan T; Ranki A; Saarialho-Kere U
Clinical and laboratory characteristics of Finnish lupus erythematosus patients with cutaneous manifestations.
Lupus 2008;17(4):337-47.
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2007: Bister Ville; Mäkitalo Laura; Jeskanen Leila; Saarialho-Kere Ulpu
Expression of MMP-9, MMP-10 and TNF-alpha and lack of epithelial MMP-1 and MMP-26 characterize pyoderma gangrenosum.
Journal of cutaneous pathology 2007;34(12):889-98.
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2007: Bister Ville; Skoog Tiina; Virolainen Susanna; Kiviluoto Tuula; Puolakkainen Pauli; Saarialho-Kere Ulpu
Increased expression of matrix metalloproteinases-21 and -26 and TIMP-4 in pancreatic adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(11):1128-40.
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2007: Järvinen T M; Kanninen P; Jeskanen L; Koskenmies S; Panelius J; Hasan T; Ranki A; Saarialho-Kere U
Matrix metalloproteinases as mediators of tissue injury in different forms of cutaneous lupus erythematosus.
The British journal of dermatology 2007;157(5):970-80.
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2007: Tiala Inkeri; Suomela Sari; Huuhtanen Jari; Wakkinen Janica; Hölttä-Vuori Maarit; Kainu Kati; Ranta Sirpa; Turpeinen Ursula; Hämäläinen Esa; Jiao Hong; Karvonen Seija-Liisa; Ikonen Elina; Kere Juha; Saarialho-Kere Ulpu; Elomaa Outi
The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes.
Journal of molecular medicine (Berlin, Germany) 2007;85(6):589-601.
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2007: Hellquist Anna; Zucchelli Marco; Kivinen Katja; Saarialho-Kere Ulpu; Koskenmies Sari; Widen Elisabeth; Julkunen Heikki; Wong Andrew; Karjalainen-Lindsberg Marja-Liisa; Skoog Tiina; Vendelin Johanna; Cunninghame-Graham Deborah S; Vyse Timothy J; Kere Juha; Lindgren Cecilia M
The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus.
Journal of medical genetics 2007;44(5):314-21.
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2007: Sihto H; Tynninen O; Bützow R; Saarialho-Kere U; Joensuu H
Endothelial cell KIT expression in human tumours.
The Journal of pathology 2007;211(4):481-8.
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2007: Pirilä Emma; Korpi Jarkko T; Korkiamäki Timo; Jahkola Tiina; Gutierrez-Fernandez Ana; Lopez-Otin Carlos; Saarialho-Kere Ulpu; Salo Tuula; Sorsa Timo
Collagenase-2 (MMP-8) and matrilysin-2 (MMP-26) expression in human wounds of different etiologies.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2007;15(1):47-57.
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2007: Orsmark Christina; Skoog Tiina; Jeskanen Leila; Kere Juha; Saarialho-Kere Ulpu
Expression of allograft inflammatory factor-1 in inflammatory skin disorders.
Acta dermato-venereologica 2007;87(3):223-7.
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2007: Suomela Sari; Kainu Kati; Onkamo Päivi; Tiala Inkeri; Himberg Johan; Koskinen Lotta; Snellman Erna; Karvonen Seija-Liisa; Karvonen Jaakko; Uurasmaa Tutta; Reunala Timo; Kivikäs Kristiina; Jansén Christer T; Holopainen Päivi; Elomaa Outi; Kere Juha; Saarialho-Kere Ulpu
Clinical associations of the risk alleles of HLA-Cw6 and CCHCR1*WWCC in psoriasis.
Acta dermato-venereologica 2007;87(2):127-34.
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2006: Skoog Tiina; Ahokas Katja; Orsmark Christina; Jeskanen Leila; Isaka Keiichi; Saarialho-Kere Ulpu
MMP-21 is expressed by macrophages and fibroblasts in vivo and in culture.
Experimental dermatology 2006;15(10):775-83.
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2006: Vendelin Johanna; Bruce Sara; Holopainen Päivi; Pulkkinen Ville; Rytilä Paula; Pirskanen Asta; Rehn Marko; Laitinen Tarja; Laitinen Lauri A; Haahtela Tari; Saarialho-Kere Ulpu; Laitinen Annika; Kere Juha
Downstream target genes of the neuropeptide S-NPSR1 pathway.
Human molecular genetics 2006;15(19):2923-35.
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2006: Kuivanen Tiina T; Jeskanen Leila; Kyllönen Lauri; Impola Ulla; Saarialho-Kere Ulpu K
Transformation-specific matrix metalloproteinases, MMP-7 and MMP-13, are present in epithelial cells of keratoacanthomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2006;19(9):1203-12.
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2006: Hahtola Sonja; Tuomela Soile; Elo Laura; Häkkinen Tiina; Karenko Leena; Nedoszytko Boguslaw; Heikkilä Hannele; Saarialho-Kere Ulpu; Roszkiewicz Jadwiga; Aittokallio Tero; Lahesmaa Riitta; Ranki Annamari
Th1 response and cytotoxicity genes are down-regulated in cutaneous T-cell lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(16):4812-21.
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2006: Forsberg Sofi; Saarialho-Kere Ulpu; Rollman Ola
Comparison of growth-inhibitory agents by fluorescence imaging of human skin re-epithelialization in vitro.
Acta dermato-venereologica 2006;86(4):292-9.
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2006: Ahokas Katja; Karjalainen-Lindsberg Marja-Liisa; Sihvo Eero; Isaka Keiichi; Salo Jarmo; Saarialho-Kere Ulpu
Matrix metalloproteinases 21 and 26 are differentially expressed in esophageal squamous cell cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2006;27(3):133-41.
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2005: Bister Ville; Kolho Kaija-Leena; Karikoski Riitta; Westerholm-Ormio Mia; Savilahti Erkki; Saarialho-Kere Ulpu
Metalloelastase (MMP-12) is upregulated in the gut of pediatric patients with potential celiac disease and in type 1 diabetes.
Scandinavian journal of gastroenterology 2005;40(12):1413-22.
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2005: Kuivanen Tiina; Ahokas Katja; Virolainen Susanna; Jahkola Tiina; Hölttä Erkki; Saksela Olli; Saarialho-Kere Ulpu
MMP-21 is upregulated at early stages of melanoma progression but disappears with more aggressive phenotype.
Virchows Archiv : an international journal of pathology 2005;447(6):954-60.
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2005: Impola U; Jeskanen L; Ravanti L; Syrjänen S; Baldursson B; Kähäri V-M; Saarialho-Kere U
Expression of matrix metalloproteinase (MMP)-7 and MMP-13 and loss of MMP-19 and p16 are associated with malignant progression in chronic wounds.
The British journal of dermatology 2005;152(4):720-6.
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2005: Ahokas Katja; Skoog Tiina; Suomela Sari; Jeskanen Leila; Impola Ulla; Isaka Keiichi; Saarialho-Kere Ulpu
Matrilysin-2 (matrix metalloproteinase-26) is upregulated in keratinocytes during wound repair and early skin carcinogenesis.
The Journal of investigative dermatology 2005;124(4):849-56.
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2005: Nakabayashi Kazuhiko; Amann Daniela; Ren Yan; Saarialho-Kere Ulpu; Avidan Nili; Gentles Simone; MacDonald Jeffrey R; Puffenberger Erik G; Christiano Angela M; Martinez-Mir Amalia; Salas-Alanis Julio C; Rizzo Renata; Vamos Esther; Raams Anja; Les Clifford; Seboun Eric; Jaspers Nicolaas G J; Beckmann Jacques S; Jackson Charles E; Scherer Stephen W
Identification of C7orf11 (TTDN1) gene mutations and genetic heterogeneity in nonphotosensitive trichothiodystrophy.
American journal of human genetics 2005;76(3):510-6.
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2005: Bister Ville; Salmela Mikko T; Heikkilä Päivi; Anttila Annaleena; Rintala Risto; Isaka Keichi; Andersson Sture; Saarialho-Kere Ulpu
Matrilysins-1 and -2 (MMP-7 and -26) and metalloelastase (MMP-12), unlike MMP-19, are up-regulated in necrotizing enterocolitis.
Journal of pediatric gastroenterology and nutrition 2005;40(1):60-6.
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2004: Weckroth M; Vaheri A; Virolainen S; Saarialho-Kere U; Jahkola T; Sirén V
Epithelial tissue-type plasminogen activator expression, unlike that of urokinase, its receptor, and plasminogen activator inhibitor-1, is increased in chronic venous ulcers.
The British journal of dermatology 2004;151(6):1189-96.
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2004: Salmela M T; Pender S L F; Karjalainen-Lindsberg M-L; Puolakkainen P; Macdonald T T; Saarialho-Kere U
Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing.
Scandinavian journal of gastroenterology 2004;39(11):1095-104.
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2004: Kuivanen Tiina; Tanskanen Maarit; Jahkola Tiina; Impola Ulla; Asko-Seljavaara Sirpa; Saarialho-Kere Ulpu
Matrilysin-1 (MMP-7) and MMP-19 are expressed by Paget's cells in extramammary Paget's disease.
Journal of cutaneous pathology 2004;31(7):483-91.
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2004: Elomaa Outi; Majuri Inkeri; Suomela Sari; Asumalahti Kati; Jiao Hong; Mirzaei Zahra; Rozell Bjorn; Dahlman-Wright Karin; Pispa Johanna; Kere Juha; Saarialho-Kere Ulpu
Transgenic mouse models support HCR as an effector gene in the PSORS1 locus.
Human molecular genetics 2004;13(15):1551-61.
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2004: Saarialho-Kere Ulpu
The gut-skin axis.
Journal of pediatric gastroenterology and nutrition 2004;39 Suppl 3():S734-5.
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2004: Bister V O; Salmela M T; Karjalainen-Lindsberg M L; Uria J; Lohi J; Puolakkainen P; Lopez-Otin C; Saarialho-Kere U
Differential expression of three matrix metalloproteinases, MMP-19, MMP-26, and MMP-28, in normal and inflamed intestine and colon cancer.
Digestive diseases and sciences 2004;49(4):653-61.
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2004: Suomela Sari; Cao Li; Bowcock Anne; Saarialho-Kere Ulpu
Interferon alpha-inducible protein 27 (IFI27) is upregulated in psoriatic skin and certain epithelial cancers.
The Journal of investigative dermatology 2004;122(3):717-21.
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2004: Häkkinen Lari; Koivisto Leeni; Gardner Humphrey; Saarialho-Kere Ulpu; Carroll Joseph M; Lakso Merja; Rauvala Heikki; Laato Matti; Heino Jyrki; Larjava Hannu
Increased expression of beta6-integrin in skin leads to spontaneous development of chronic wounds.
The American journal of pathology 2004;164(1):229-42.
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2004: Impola U; Uitto V J; Hietanen J; Hakkinen L; Zhang L; Larjava H; Isaka K; Saarialho-Kere U
Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer.
The Journal of pathology 2004;202(1):14-22.
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2003: Ahokas Katja; Lohi Jouko; Illman Sara A; Llano Elena; Elomaa Outi; Impola Ulla; Karjalainen-Lindsberg Marja-Liisa; Saarialho-Kere Ulpu
Matrix metalloproteinase-21 is expressed epithelially during development and in cancer and is up-regulated by transforming growth factor-beta1 in keratinocytes.
Laboratory investigation; a journal of technical methods and pathology 2003;83(12):1887-99.
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2003: Suomela Sari; Elomaa Outi; Asumalahti Kati; Kariniemi Arja Leena; Karvonen Seija Liisa; Peltonen Juha; Kere Juha; Saarialho-Kere Ulpu
HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes.
The Journal of investigative dermatology 2003;121(6):1360-4.
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2003: Daniels Julie T; Geerling Gerd; Alexander Robert A; Murphy Gillian; Khaw Peng T; Saarialho-Kere Ulpu
Temporal and spatial expression of matrix metalloproteinases during wound healing of human corneal tissue.
Experimental eye research 2003;77(6):653-64.
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2003: Hieta Niina; Impola Ulla; López-Otín Carlos; Saarialho-Kere Ulpu; Kähäri Veli-Matti
Matrix metalloproteinase-19 expression in dermal wounds and by fibroblasts in culture.
The Journal of investigative dermatology 2003;121(5):997-1004.
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2003: Asumalahti Kati; Laitinen Tarja; Lahermo Päivi; Suomela Sari; Itkonen-Vatjus Raija; Jansen Christer; Karvonen Jaakko; Karvonen Seija-Liisa; Reunala Timo; Snellman Erna; Uurasmaa Tutta; Saarialho-Kere Ulpu; Kere Juha
Psoriasis susceptibility locus on 18p revealed by genome scan in Finnish families not associated with PSORS1.
The Journal of investigative dermatology 2003;121(4):735-40.
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2003: Impola U; Cuccuru M A; Masala M V; Jeskanen L; Cottoni F; Saarialho-Kere U
Preliminary communication: matrix metalloproteinases in Kaposi's sarcoma.
The British journal of dermatology 2003;149(4):905-7.
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2003: Kerkelä E; Saarialho-Kere U
Matrix metalloproteinases in tumor progression: focus on basal and squamous cell skin cancer.
Experimental dermatology 2003;12(2):109-25.
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2003: Asumalahti Kati; Ameen Mahreen; Suomela Sari; Hagforsen Eva; Michaëlsson Gerd; Evans Julie; Munro Margo; Veal Colin; Allen Michael; Leman Joyce; David Burden A; Kirby Brian; Connolly Maureen; Griffiths Christopher E M; Trembath Richard C; Kere Juha; Saarialho-Kere Ulpu; Barker Jonathan N W N
Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantar pustulosis.
The Journal of investigative dermatology 2003;120(4):627-32.
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2003: Daniels Julie T; Limb G Astrid; Saarialho-Kere Ulpu; Murphy Gillian; Khaw Peng T
Human corneal epithelial cells require MMP-1 for HGF-mediated migration on collagen I.
Investigative ophthalmology & visual science 2003;44(3):1048-55.
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2003: Impola Ulla; Toriseva Mervi; Suomela Sari; Jeskanen Leila; Hieta Niina; Jahkola Tiina; Grenman Reidar; Kähäri Veli-Matti; Saarialho-Kere Ulpu
Matrix metalloproteinase-19 is expressed by proliferating epithelium but disappears with neoplastic dedifferentiation.
International journal of cancer. Journal international du cancer 2003;103(6):709-16.
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2003: Salmela M T; Karjalainen-Lindsberg M L; Jeskanen L; Saarialho-Kere U
Overexpression of tissue inhibitor of metalloproteinases-3 in intestinal and cutaneous lesions of graft-versus-host disease.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2003;16(2):108-14.
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2003: Asumalahti Kati; Saarialho-Kere Ulpu; Kere Juha
[The pathogenesis of psoriasis--investigating the genetics of a multifactorial disease]
Duodecim; lääketieteellinen aikakauskirja 2003;119(16):1517-22.
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2003: Suomela Sari; Kariniemi Arja-Leena; Impola Ulla; Karvonen Seija-Liisa; Snellman Erna; Uurasmaa Tutta; Peltonen Juha; Saarialho-Kere Ulpu
Matrix metalloproteinase-19 is expressed by keratinocytes in psoriasis.
Acta dermato-venereologica 2003;83(2):108-14.
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2002: Ahokas Katja; Lohi Jouko; Lohi Hannes; Elomaa Outi; Karjalainen-Lindsberg Marja Liisa; Kere Juha; Saarialho-Kere Ulpu
Matrix metalloproteinase-21, the human orthologue for XMMP, is expressed during fetal development and in cancer.
Gene 2002;301(1-2):31-41.
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2002: Kerkelä Erja; Ala-aho Risto; Klemi Pekka; Grénman Seija; Shapiro Steven D; Kähäri Veli-Matti; Saarialho-Kere Ulpu
Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.
The Journal of pathology 2002;198(2):258-69.
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2002: Salmela M T; MacDonald T T; Black D; Irvine B; Zhuma T; Saarialho-Kere U; Pender S L F
Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation.
Gut 2002;51(4):540-7.
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2002: Saarialho-Kere Ulpu; Kerkelä Erja; Jahkola Tiina; Suomela Sari; Keski-Oja Jorma; Lohi Jouko
Epilysin (MMP-28) expression is associated with cell proliferation during epithelial repair.
The Journal of investigative dermatology 2002;119(1):14-21.
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2002: Ahonen Matti; Ala-Aho Risto; Baker Andrew H; George Sarah J; Grénman Reidar; Saarialho-Kere Ulpu; Kähäri Veli-Matti
Antitumor activity and bystander effect of adenovirally delivered tissue inhibitor of metalloproteinases-3.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(6):705-15.
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2002: Laurikkala Johanna; Pispa Johanna; Jung Han-Sung; Nieminen Pekka; Mikkola Marja; Wang Xiuping; Saarialho-Kere Ulpu; Galceran Juan; Grosschedl Rudolf; Thesleff Irma
Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar.
Development (Cambridge, England) 2002;129(10):2541-53.
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2002: Uitto V-J; Salonen J I; Firth J D; Jousimies-Somer H; Saarialho-Kere U
Matrilysin (matrix metalloproteinase-7) expression in human junctional epithelium.
Journal of dental research 2002;81(4):241-6.
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2002: Lohi Hannes; Kujala Minna; Makela Siru; Lehtonen Eero; Kestila Marjo; Saarialho-Kere Ulpu; Markovich Daniel; Kere Juha
Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9.
The Journal of biological chemistry 2002;277(16):14246-54.
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2002: Mirastschijski Ursula; Impola Ulla; Jahkola Tiina; Karlsmark Tonny; AGren Magnus S; Saarialho-Kere Ulpu
Ectopic localization of matrix metalloproteinase-9 in chronic cutaneous wounds.
Human pathology 2002;33(3):355-64.
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2002: Asumalahti Kati; Veal Colin; Laitinen Tarja; Suomela Sari; Allen Michael; Elomaa Outi; Moser Michael; de Cid Rafael; Ripatti Samuli; Vorechovsky Igor; Marcusson Jan A; Nakagawa Hidemi; Lazaro Conxi; Estivill Xavier; Capon Francesca; Novelli Giuseppe; Saarialho-Kere Ulpu; Barker Jonathan; Trembath Richard; Kere Juha;
Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus.
Human molecular genetics 2002;11(5):589-97.
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2002: Mirastschijski Ursula; Impola Ulla; Karsdal Morten A; Saarialho-Kere Ulpu; Agren Magnus S
Matrix metalloproteinase inhibitor BB-3103 unlike the serine proteinase inhibitor aprotinin abrogates epidermal healing of human skin wounds ex vivo.
The Journal of investigative dermatology 2002;118(1):55-64.
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2001: Kerkelä E; Böhling T; Herva R; Uria J A; Saarialho-Kere U
Human macrophage metalloelastase (MMP-12) expression is induced in chondrocytes during fetal development and malignant transformation.
Bone 2001;29(5):487-93.
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2001: Agren M S; Mirastschijski U; Karlsmark T; Saarialho-Kere U K
Topical synthetic inhibitor of matrix metalloproteinases delays epidermal regeneration of human wounds.
Experimental dermatology 2001;10(5):337-48.
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2001: Virolainen E; Niemi K M; Gånemo A; Kere J; Vahlquist A; Saarialho-Kere U
Ultrastructural features resembling those of harlequin ichthyosis in patients with severe congenital ichthyosiform erythroderma.
The British journal of dermatology 2001;145(3):480-3.
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2001: Salmela M T; Karjalainen-Lindsberg M L; Puolakkainen P; Saarialho-Kere U
Upregulation and differential expression of matrilysin (MMP-7) and metalloelastase (MMP-12) and their inhibitors TIMP-1 and TIMP-3 in Barrett's oesophageal adenocarcinoma.
British journal of cancer 2001;85(3):383-92.
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2001: Haila S; Hästbacka J; Böhling T; Karjalainen-Lindsberg M L; Kere J; Saarialho-Kere U
SLC26A2 (diastrophic dysplasia sulfate transporter) is expressed in developing and mature cartilage but also in other tissues and cell types.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(8):973-82.
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2001: Suomela S; Kariniemi A L; Snellman E; Saarialho-Kere U
Metalloelastase (MMP-12) and 92-kDa gelatinase (MMP-9) as well as their inhibitors, TIMP-1 and -3, are expressed in psoriatic lesions.
Experimental dermatology 2001;10(3):175-83.
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2001: Elomaa O; Pulkkinen K; Hannelius U; Mikkola M; Saarialho-Kere U; Kere J
Ectodysplasin is released by proteolytic shedding and binds to the EDAR protein.
Human molecular genetics 2001;10(9):953-62.
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2001: Salmela M T; Pender S L; Reunala T; MacDonald T; Saarialho-Kere U
Parallel expression of macrophage metalloelastase (MMP-12) in duodenal and skin lesions of patients with dermatitis herpetiformis.
Gut 2001;48(4):496-502.
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2001: Kerkelä E; Ala-aho R; Lohi J; Grénman R; M-Kähäri V; Saarialho-Kere U
Differential patterns of stromelysin-2 (MMP-10) and MT1-MMP (MMP-14) expression in epithelial skin cancers.
British journal of cancer 2001;84(5):659-69.
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2000: Pender S L; Salmela M T; Monteleone G; Schnapp D; McKenzie C; Spencer J; Fong S; Saarialho-Kere U; MacDonald T T
Ligation of alpha4ss1 integrin on human intestinal mucosal mesenchymal cells selectively Up-regulates membrane type-1 matrix metalloproteinase and confers a migratory phenotype.
The American journal of pathology 2000;157(6):1955-62.
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2000: Lohi H; Kujala M; Kerkelä E; Saarialho-Kere U; Kestilä M; Kere J
Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger.
Genomics 2000;70(1):102-12.
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2000: Rechardt O; Elomaa O; Vaalamo M; Pääkkönen K; Jahkola T; Höök-Nikanne J; Hembry R M; Häkkinen L; Kere J; Saarialho-Kere U
Stromelysin-2 is upregulated during normal wound repair and is induced by cytokines.
The Journal of investigative dermatology 2000;115(5):778-87.
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2000: Asumalahti K; Laitinen T; Itkonen-Vatjus R; Lokki M L; Suomela S; Snellman E; Saarialho-Kere U; Kere J
A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele.
Human molecular genetics 2000;9(10):1533-42.
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2000: Kerkelä E; Ala-Aho R; Jeskanen L; Rechardt O; Grénman R; Shapiro S D; Kähäri V M; Saarialho-Kere U
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
The Journal of investigative dermatology 2000;114(6):1113-9.
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2000: Haila S; Saarialho-Kere U; Karjalainen-Lindsberg M L; Lohi H; Airola K; Holmberg C; Hästbacka J; Kere J; Höglund P
The congenital chloride diarrhea gene is expressed in seminal vesicle, sweat gland, inflammatory colon epithelium, and in some dysplastic colon cells.
Histochemistry and cell biology 2000;113(4):279-86.
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1999: Ravanti L; Häkkinen L; Larjava H; Saarialho-Kere U; Foschi M; Han J; Kähäri V M
Transforming growth factor-beta induces collagenase-3 expression by human gingival fibroblasts via p38 mitogen-activated protein kinase.
The Journal of biological chemistry 1999;274(52):37292-300.
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1999: Saarialho-Kere U; Kerkelä E; Jeskanen L; Hasan T; Pierce R; Starcher B; Raudasoja R; Ranki A; Oikarinen A; Vaalamo M
Accumulation of matrilysin (MMP-7) and macrophage metalloelastase (MMP-12) in actinic damage.
The Journal of investigative dermatology 1999;113(4):664-72.
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1999: Laiho E; Niemi K M; Ignatius J; Kere J; Palotie A; Saarialho-Kere U
Clinical and morphological correlations for transglutaminase 1 gene mutations in autosomal recessive congenital ichthyosis.
European journal of human genetics : EJHG 1999;7(6):625-32.
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1999: Vaalamo M; Leivo T; Saarialho-Kere U
Differential expression of tissue inhibitors of metalloproteinases (TIMP-1, -2, -3, and -4) in normal and aberrant wound healing.
Human pathology 1999;30(7):795-802.
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1999: Airola K; Karonen T; Vaalamo M; Lehti K; Lohi J; Kariniemi A L; Keski-Oja J; Saarialho-Kere U K
Expression of collagenases-1 and -3 and their inhibitors TIMP-1 and -3 correlates with the level of invasion in malignant melanomas.
British journal of cancer 1999;80(5-6):733-43.
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1999: Vaalamo M; Kariniemi A L; Shapiro S D; Saarialho-Kere U
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
The Journal of investigative dermatology 1999;112(4):499-505.
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1999: Kähäri V M; Saarialho-Kere U
Matrix metalloproteinases and their inhibitors in tumour growth and invasion.
Annals of medicine 1999;31(1):34-45.
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1999: Johansson N; Vaalamo M; Grénman S; Hietanen S; Klemi P; Saarialho-Kere U; Kähäri V M
Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas.
The American journal of pathology 1999;154(2):469-80.
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1998: Montonen O; Ezer S; Laurikkala J; Karjalainen-Lindsberg M L; Thesleff I; Kere J; Saarialho-Kere U
Expression of the anhidrotic ectodermal dysplasia gene is reduced in skin cancer coinciding with reduced E-cadherin.
Experimental dermatology 1998;7(4):168-74.
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1998: Saarialho-Kere U K
Patterns of matrix metalloproteinase and TIMP expression in chronic ulcers.
Archives of dermatological research 1998;290 Suppl():S47-54.
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1998: Uitto V J; Airola K; Vaalamo M; Johansson N; Putnins E E; Firth J D; Salonen J; López-Otín C; Saarialho-Kere U; Kähäri V M
Collagenase-3 (matrix metalloproteinase-13) expression is induced in oral mucosal epithelium during chronic inflammation.
The American journal of pathology 1998;152(6):1489-99.
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1998: Vaalamo M; Karjalainen-Lindsberg M L; Puolakkainen P; Kere J; Saarialho-Kere U
Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations.
The American journal of pathology 1998;152(4):1005-14.
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1998: Mattila L; Airola K; Ahonen M; Hietarinta M; Black C; Saarialho-Kere U; Kähäri V M
Activation of tissue inhibitor of metalloproteinases-3 (TIMP-3) mRNA expression in scleroderma skin fibroblasts.
The Journal of investigative dermatology 1998;110(4):416-21.
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1998: Airola K; Ahonen M; Johansson N; Heikkilä P; Kere J; Kähäri V M; Saarialho-Kere U K
Human TIMP-3 is expressed during fetal development, hair growth cycle, and cancer progression.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(4):437-47.
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1998: Montonen O; Ezer S; Saarialho-Kere U K; Herva R; Karjalainen-Lindsberg M L; Kaitila I; Schlessinger D; Srivastava A K; Thesleff I; Kere J
The gene defective in anhidrotic ectodermal dysplasia is expressed in the developing epithelium, neuroectoderm, thymus, and bone.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(3):281-9.
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1998: Kähäri V M; Johansson N; Grénman R; Airola K; Saarialho-Kere U
Expression of collagenase-3 (MMP-13) by tumor cells in squamous cell carcinomas of the head and neck.
Advances in experimental medicine and biology 1998;451():63-8.
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1997: Kähäri V M; Saarialho-Kere U
Matrix metalloproteinases in skin.
Experimental dermatology 1997;6(5):199-213.
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1997: Laiho E; Ignatius J; Mikkola H; Yee V C; Teller D C; Niemi K M; Saarialho-Kere U; Kere J; Palotie A
Transglutaminase 1 mutations in autosomal recessive congenital ichthyosis: private and recurrent mutations in an isolated population.
American journal of human genetics 1997;61(3):529-38.
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1997: Johansson N; Airola K; Grénman R; Kariniemi A L; Saarialho-Kere U; Kähäri V M
Expression of collagenase-3 (matrix metalloproteinase-13) in squamous cell carcinomas of the head and neck.
The American journal of pathology 1997;151(2):499-508.
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1997: Airola K; Johansson N; Kariniemi A L; Kähäri V M; Saarialho-Kere U K
Human collagenase-3 is expressed in malignant squamous epithelium of the skin.
The Journal of investigative dermatology 1997;109(2):225-31.
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1997: Vaalamo M; Mattila L; Johansson N; Kariniemi A L; Karjalainen-Lindsberg M L; Kähäri V M; Saarialho-Kere U
Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds.
The Journal of investigative dermatology 1997;109(1):96-101.
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1997: Johansson N; Saarialho-Kere U; Airola K; Herva R; Nissinen L; Westermarck J; Vuorio E; Heino J; Kähäri V M
Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;208(3):387-97.
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1997: Airola K; Reunala T; Salo S; Saarialho-Kere U K
Urokinase plasminogen activator is expressed by basal keratinocytes before interstitial collagenase, stromelysin-1, and laminin-5 in experimentally induced dermatitis herpetiformis lesions.
The Journal of investigative dermatology 1997;108(1):7-11.
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1996: Höglund P; Haila S; Socha J; Tomaszewski L; Saarialho-Kere U; Karjalainen-Lindsberg M L; Airola K; Holmberg C; de la Chapelle A; Kere J
Mutations of the Down-regulated in adenoma (DRA) gene cause congenital chloride diarrhoea.
Nature genetics 1996;14(3):316-9.
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1996: Kere J; Srivastava A K; Montonen O; Zonana J; Thomas N; Ferguson B; Munoz F; Morgan D; Clarke A; Baybayan P; Chen E Y; Ezer S; Saarialho-Kere U; de la Chapelle A; Schlessinger D
X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein.
Nature genetics 1996;13(4):409-16.
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1996: Vaalamo M; Weckroth M; Puolakkainen P; Kere J; Saarinen P; Lauharanta J; Saarialho-Kere U K
Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds.
The British journal of dermatology 1996;135(1):52-9.
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1996: Saarialho-Kere U K; Vaalamo M; Puolakkainen P; Airola K; Parks W C; Karjalainen-Lindsberg M L
Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers.
The American journal of pathology 1996;148(2):519-26.
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1996: Srivastava A K; Montonen O; Saarialho-Kere U; Chen E; Baybayan P; Pispa J; Limon J; Schlessinger D; Kere J
Fine mapping of the EDA gene: a translocation breakpoint is associated with a CpG island that is transcribed.
American journal of human genetics 1996;58(1):126-32.
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1995: Airola K; Vaalamo M; Reunala T; Saarialho-Kere U K
Enhanced expression of interstitial collagenase, stromelysin-1, and urokinase plasminogen activator in lesions of dermatitis herpetiformis.
The Journal of investigative dermatology 1995;105(2):184-9.
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1995: Saarialho-Kere U K; Vaalamo M; Airola K; Niemi K M; Oikarinen A I; Parks W C
Interstitial collagenase is expressed by keratinocytes that are actively involved in reepithelialization in blistering skin disease.
The Journal of investigative dermatology 1995;104(6):982-8.
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1989: Saarialho-Kere U; Mattila M J; Seppälä T
Psychomotor, respiratory and neuroendocrinological effects of a mu-opioid receptor agonist (oxycodone) in healthy volunteers.
Pharmacology & toxicology 1989;65(4):252-7.
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1988: Saarialho-Kere U; Julkunen H; Mattila M J; Seppälä T
Psychomotor performance of patients with rheumatoid arthritis: cross-over comparison of dextropropoxyphene, dextropropoxyphene plus amitriptyline, indomethacin, and placebo.
Pharmacology & toxicology 1988;63(4):286-92.
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1988: Mattila M J; Saarialho-Kere U; Mattila M
Acute effects of sertraline, amitriptyline, and placebo on the psychomotor performance of healthy subjects over 50 years of age.
The Journal of clinical psychiatry 1988;49 Suppl():52-8.
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1988: Saarialho-Kere U
Psychomotor, respiratory and neuroendocrinological effects of nalbuphine and haloperidol, alone and in combination, in healthy subjects.
British journal of clinical pharmacology 1988;26(1):79-87.
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1988: Saarialho-Kere U; Mattila M J; Seppälä T
Parenteral pentazocine: effects on psychomotor skills and respiration, and interactions with amitriptyline.
European journal of clinical pharmacology 1988;35(5):483-9.
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1987: Saarialho-Kere U; Mattila M J; Paloheimo M; Seppälä T
Psychomotor, respiratory and neuroendocrinological effects of buprenorphine and amitriptyline in healthy volunteers.
European journal of clinical pharmacology 1987;33(2):139-46.
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