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John Sacci
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21
Azad, Abdu
18
Hoffman, Stephen
11
Charoenvit, Yupin
8
Sedegah, Martha
7
Aguiar, Joao
6
Wang, Ruobing
6
de la Vega, Patricia
6
Hedstrom, Richard
6
Carucci, Daniel
5
Witney, Adam
5
Doolan, Denise
5
PIERCE, NATHANIEL
4
Kumar, Nirbhay
4
Lau, Audrey
4
Hobart, Peter
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Geonetwork of John Sacci (preview)
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All Publications
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2010: Mackellar Drew C; O'Neill Matthew T; Aly Ahmed S I; Sacci John B; Cowman Alan F; Kappe Stefan H I
Plasmodium falciparum PF10_0164 (ETRAMP10.3) is an essential parasitophorous vacuole and exported protein in blood stages.
Eukaryotic cell 2010;9(5):784-94.
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2009: House Brent L; Hollingdale Michael R; Sacci John B; Richie Thomas L
Functional immunoassays using an in-vitro malaria liver-stage infection model: where do we go from here?
Trends in parasitology 2009;25(11):525-33.
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2009: VanBuskirk Kelley M; O'Neill Matthew T; De La Vega Patricia; Maier Alexander G; Krzych Urszula; Williams Jack; Dowler Megan G; Sacci John B; Kangwanrangsan Niwat; Tsuboi Takafumi; Kneteman Norman M; Heppner Donald G; Murdock Brant A; Mikolajczak Sebastian A; Aly Ahmed S I; Cowman Alan F; Kappe Stefan H I
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(31):13004-9.
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2009: Nguyen Thanh V; Sacci John B; de la Vega Patricia; John Chandy C; James Anthony A; Kang Angray S
Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB2 in malaria exposed individuals.
Malaria journal 2009;8():235.
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2007: Chakravarty Sumana; Cockburn Ian A; Kuk Salih; Overstreet Michael G; Sacci John B; Zavala Fidel
CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes.
Nature medicine 2007;13(9):1035-41.
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2007: Epstein Judith E; Rao Suchitra; Williams Frank; Freilich Daniel; Luke Thomas; Sedegah Martha; de la Vega Patricia; Sacci John; Richie Thomas L; Hoffman Stephen L
Safety and clinical outcome of experimental challenge of human volunteers with Plasmodium falciparum-infected mosquitoes: an update.
The Journal of infectious diseases 2007;196(1):145-54.
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2006: Sacci John B; Alam Uzma; Douglas Donna; Lewis Jamie; Tyrrell D Lorne J; Azad Abdu F; Kneteman Norman M
Plasmodium falciparum infection and exoerythrocytic development in mice with chimeric human livers.
International journal for parasitology 2006;36(3):353-60.
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2006: Porter-Kelley Johanna M; Dinglasan Rhoel R; Alam Uzma; Ndeta George A; Sacci John B; Azad Abdu F
Plasmodium yoelii: axenic development of the parasite mosquito stages.
Experimental parasitology 2006;112(2):99-108.
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2005: Zhang Quan; Guan Jian; Sacci John; Ager Arba; Ellis William; Milhous Wilbur; Kyle Dennis; Lin Ai J
Unambiguous synthesis and prophylactic antimalarial activities of imidazolidinedione derivatives.
Journal of medicinal chemistry 2005;48(20):6472-81.
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2005: Sacci John B; Ribeiro Jose M C; Huang Fengying; Alam Uzma; Russell Joshua A; Blair Peter L; Witney Adam; Carucci Daniel J; Azad Abdu F; Aguiar Joao C
Transcriptional analysis of in vivo Plasmodium yoelii liver stage gene expression.
Molecular and biochemical parasitology 2005;142(2):177-83.
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2004: Sedegah M; Charoenvit Y; Aguiar J; Sacci J; Hedstrom R; Kumar S; Belmonte A; Lanar D E; Jones T R; Abot E; Druilhe P; Corradin G; Epstein J E; Richie T L; Carucci D J; Hoffman S L
Effect on antibody and T-cell responses of mixing five GMP-produced DNA plasmids and administration with plasmid expressing GM-CSF.
Genes and immunity 2004;5(7):553-61.
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2004: Aguiar João Carlos; LaBaer Joshua; Blair Peter L; Shamailova Victoria Y; Koundinya Malvika; Russell Joshua A; Huang Fengying; Mar Wenhong; Anthony Robert M; Witney Adam; Caruana Sonia R; Brizuela Leonardo; Sacci John B; Hoffman Stephen L; Carucci Daniel J
High-throughput generation of P. falciparum functional molecules by recombinational cloning.
Genome research 2004;14(10B):2076-82.
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2003: Dinglasan Rhoel R; Fields Iesha; Shahabuddin Mohammed; Azad Abdu F; Sacci John B
Monoclonal antibody MG96 completely blocks Plasmodium yoelii development in Anopheles stephensi.
Infection and immunity 2003;71(12):6995-7001.
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2003: Rathore Dharmendar; Hrstka Sybil C L; Sacci John B; De la Vega Patricia; Linhardt Robert J; Kumar Sanjai; McCutchan Thomas F
Molecular mechanism of host specificity in Plasmodium falciparum infection: role of circumsporozoite protein.
The Journal of biological chemistry 2003;278(42):40905-10.
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2003: Gaywee Jariyanart; Sacci John B; Radulovic Suzana; Beier Magda S; Azad Abdu F
Subcellular localization of rickettsial invasion protein, InvA.
The American journal of tropical medicine and hygiene 2003;68(1):92-6.
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2002: Sacci John B; Azad Abdu F
Gene expression analysis during liver stage development of Plasmodium.
International journal for parasitology 2002;32(13):1551-7.
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2002: Florens Laurence; Washburn Michael P; Raine J Dale; Anthony Robert M; Grainger Munira; Haynes J David; Moch J Kathleen; Muster Nemone; Sacci John B; Tabb David L; Witney Adam A; Wolters Dirk; Wu Yimin; Gardner Malcolm J; Holder Anthony A; Sinden Robert E; Yates John R; Carucci Daniel J
A proteomic view of the Plasmodium falciparum life cycle.
Nature 2002;419(6906):520-6.
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2002: Hoffman Stephen L; Goh Lucy M L; Luke Thomas C; Schneider Imogene; Le Thong P; Doolan Denise L; Sacci John; de la Vega Patricia; Dowler Megan; Paul Chris; Gordon Daniel M; Stoute Jose A; Church L W Preston; Sedegah Martha; Heppner D Gray; Ballou W Ripley; Richie Thomas L
Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites.
The Journal of infectious diseases 2002;185(8):1155-64.
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2002: Rathore Dharmendar; Sacci John B; de la Vega Patricia; McCutchan Thomas F
Binding and invasion of liver cells by Plasmodium falciparum sporozoites. Essential involvement of the amino terminus of circumsporozoite protein.
The Journal of biological chemistry 2002;277(9):7092-8.
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2002: Sacci John B; Aguiar Joao C; Lau Audrey O; Hoffman Stephen L
Laser capture microdissection and molecular analysis of Plasmodium yoelii liver-stage parasites.
Molecular and biochemical parasitology 2002;119(2):285-9.
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2002: Sacci John B
Inhibition of liver-stage development assay.
Methods in molecular medicine 2002;72():517-20.
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2002: Sacci John B
Hepatocyte perfusion, isolation, and culture.
Methods in molecular medicine 2002;72():503-5.
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2002: Sacci John B
Hepatic portal branch inoculation.
Methods in molecular medicine 2002;72():499-501.
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2001: Kolodny N; Kitov S; Vassell M A; Miller V L; Ware L A; Fegeding K; De La Vega P; Sacci J B; Lanar D E
Two-step chromatographic purification of recombinant Plasmodium falciparum circumsporozoite protein from Escherichia coli.
Journal of chromatography. B, Biomedical sciences and applications 2001;762(1):77-86.
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2001: Aguiar J C; Hedstrom R C; Rogers W O; Charoenvit Y; Sacci J B; Lanar D E; Majam V F; Stout R R; Hoffman S L
Enhancement of the immune response in rabbits to a malaria DNA vaccine by immunization with a needle-free jet device.
Vaccine 2001;20(1-2):275-80.
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2001: Joshi M B; Gam A A; Boykins R A; Kumar S; Sacci J; Hoffman S L; Nakhasi H L; Kenney R T
Immunogenicity of well-characterized synthetic Plasmodium falciparum multiple antigen peptide conjugates.
Infection and immunity 2001;69(8):4884-90.
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2001: Sanchez G I; Sedegah M; Rogers W O; Jones T R; Sacci J; Witney A; Carucci D J; Kumar N; Hoffman S L
Immunogenicity and protective efficacy of a Plasmodium yoelii Hsp60 DNA vaccine in BALB/c mice.
Infection and immunity 2001;69(6):3897-905.
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2001: Lal A A; Patterson P S; Sacci J B; Vaughan J A; Paul C; Collins W E; Wirtz R A; Azad A F
Anti-mosquito midgut antibodies block development of Plasmodium falciparum and Plasmodium vivax in multiple species of Anopheles mosquitoes and reduce vector fecundity and survivorship.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):5228-33.
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2001: Lau A O; Sacci J B; Azad A F
Detection of Plasmodium yoelii stage mRNA in BALB/c mice.
The Journal of parasitology 2001;87(1):19-23.
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2001: Lau A O; Sacci J B; Azad A F
Host responses to Plasmodium yoelii hepatic stages: a paradigm in host-parasite interaction.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1945-50.
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2000: Silbergeld E K; Sacci J B; Azad A F
Mercury exposure and murine response to Plasmodium yoelii infection and immunization.
Immunopharmacology and immunotoxicology 2000;22(4):685-95.
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2000: Lau A O; Sacci J B; Azad A F
Retrieving parasite specific liver stage gene products in Plasmodium yoelii infected livers using differential display.
Molecular and biochemical parasitology 2000;111(1):143-51.
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2000: Wang L; Menting J G; Stowers A; Charoenvit Y; Sacci J B; Coppel R L
Antigens cross reactive with Plasmodium falciparum merozoite surface protein 4 are found in pre-erythrocytic and sexual stages.
Molecular and biochemical parasitology 2000;109(2):189-94.
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2000: Sedegah M; Weiss W; Sacci J B; Charoenvit Y; Hedstrom R; Gowda K; Majam V F; Tine J; Kumar S; Hobart P; Hoffman S L
Improving protective immunity induced by DNA-based immunization: priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):5905-12.
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2000: Franke E D; Sette A; Sacci J; Southwood S; Corradin G; Hoffman S L
A subdominant CD8(+) cytotoxic T lymphocyte (CTL) epitope from the Plasmodium yoelii circumsporozoite protein induces CTLs that eliminate infected hepatocytes from culture.
Infection and immunity 2000;68(6):3403-11.
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2000: McKenna K C; Tsuji M; Sarzotti M; Sacci J B; Witney A A; Azad A F
gammadelta T cells are a component of early immunity against preerythrocytic malaria parasites.
Infection and immunity 2000;68(4):2224-30.
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1999: Sanchez G I; Carucci D J; Sacci J; Resau J H; Rogers W O; Kumar N; Hoffman S L
Plasmodium yoelii: cloning and characterization of the gene encoding for the mitochondrial heat shock protein 60.
Experimental parasitology 1999;93(4):181-90.
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1999: Charoenvit Y; Majam V F; Corradin G; Sacci J B; Wang R; Doolan D L; Jones T R; Abot E; Patarroyo M E; Guzman F; Hoffman S L
CD4(+) T-cell- and gamma interferon-dependent protection against murine malaria by immunization with linear synthetic peptides from a Plasmodium yoelii 17-kilodalton hepatocyte erythrocyte protein.
Infection and immunity 1999;67(11):5604-14.
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1999: Franke E D; Hoffman S L; Sacci J B; Wang R; Charoenvit Y; Appella E; Chesnut R; Alexander J; Del Guercio M F; Sette A
Pan DR binding sequence provides T-cell help for induction of protective antibodies against Plasmodium yoelii sporozoites.
Vaccine 1999;17(9-10):1201-5.
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1999: Loyevsky M; Sacci J B; Boehme P; Weglicki W; John C; Gordeuk V R
Plasmodium falciparum and Plasmodium yoelii: effect of the iron chelation prodrug dexrazoxane on in vitro cultures.
Experimental parasitology 1999;91(2):105-14.
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1999: Shi Y P; Hasnain S E; Sacci J B; Holloway B P; Fujioka H; Kumar N; Wohlhueter R; Hoffman S L; Collins W E; Lal A A
Immunogenicity and in vitro protective efficacy of a recombinant multistage Plasmodium falciparum candidate vaccine.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1615-20.
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1998: Wang R; Doolan D L; Charoenvit Y; Hedstrom R C; Gardner M J; Hobart P; Tine J; Sedegah M; Fallarme V; Sacci J B; Kaur M; Klinman D M; Hoffman S L; Weiss W R
Simultaneous induction of multiple antigen-specific cytotoxic T lymphocytes in nonhuman primates by immunization with a mixture of four Plasmodium falciparum DNA plasmids.
Infection and immunity 1998;66(9):4193-202.
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1998: Hedstrom R C; Doolan D L; Wang R; Kumar A; Sacci J B; Gardner M J; Aguiar J C; Charoenvit Y; Sedegah M; Tine J A; Margalith M; Hobart P; Hoffman S L
In vitro expression and in vivo immunogenicity of Plasmodium falciparum pre-erythrocytic stage DNA vaccines.
International journal of molecular medicine 1998;2(1):29-38.
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1998: Le T P; Church L W; Corradin G; Hunter R L; Charoenvit Y; Wang R; de la Vega P; Sacci J; Ballou W R; Kolodny N; Kitov S; Glenn G M; Richards R L; Alving C R; Hoffman S L
Immunogenicity of Plasmodium falciparum circumsporozoite protein multiple antigen peptide vaccine formulated with different adjuvants.
Vaccine 1998;16(2-3):305-12.
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1998: Alexander J; Fikes J; Hoffman S; Franke E; Sacci J; Appella E; Chisari F V; Guidotti L G; Chesnut R W; Livingston B; Sette A
The optimization of helper T lymphocyte (HTL) function in vaccine development.
Immunologic research 1998;18(2):79-92.
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1997: Charoenvit Y; Fallarme V; Rogers W O; Sacci J B; Kaur M; Aguiar J C; Yuan L F; Corradin G; Andersen E; Wizel B; Houghten R A; Oloo A; De la Vega P; Hoffman S L
Development of two monoclonal antibodies against Plasmodium falciparum sporozoite surface protein 2 and mapping of B-cell epitopes.
Infection and immunity 1997;65(8):3430-7.
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1997: Hedstrom R C; Doolan D L; Wang R; Gardner M J; Kumar A; Sedegah M; Gramzinski R A; Sacci J B; Charoenvit Y; Weiss W R; Margalith M; Norman J A; Hobart P; Hoffman S L
The development of a multivalent DNA vaccine for malaria.
Springer seminars in immunopathology 1997;19(2):147-59.
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1995: Hoffman S L; Sacci J B
Rationale and approaches to constructing preerythrocytic malaria vaccines.
Pharmaceutical biotechnology 1995;6():787-802.
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1994: Schriefer M E; Sacci J B; Taylor J P; Higgins J A; Azad A F
Murine typhus: updated roles of multiple urban components and a second typhuslike rickettsia.
Journal of medical entomology 1994;31(5):681-5.
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1994: Schriefer M E; Sacci J B; Dumler J S; Bullen M G; Azad A F
Identification of a novel rickettsial infection in a patient diagnosed with murine typhus.
Journal of clinical microbiology 1994;32(4):949-54.
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1994: Higgins J A; Sacci J B; Schriefer M E; Endris R G; Azad A F
Molecular identification of rickettsia-like microorganisms associated with colonized cat fleas (Ctenocephalides felis).
Insect molecular biology 1994;3(1):27-33.
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1994: Lal A A; Schriefer M E; Sacci J B; Goldman I F; Louis-Wileman V; Collins W E; Azad A F
Inhibition of malaria parasite development in mosquitoes by anti-mosquito-midgut antibodies.
Infection and immunity 1994;62(1):316-8.
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1993: Kumar N; Nagasawa H; Sacci J B; Sina B J; Aikawa M; Atkinson C; Uparanukraw P; Kubiak L B; Azad A F; Hollingdale M R
Expression of members of the heat-shock protein 70 family in the exoerythrocytic stages of Plasmodium berghei and Plasmodium falciparum.
Parasitology research 1993;79(2):109-13.
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1992: Williams S G; Sacci J B; Schriefer M E; Andersen E M; Fujioka K K; Sorvillo F J; Barr A R; Azad A F
Typhus and typhuslike rickettsiae associated with opossums and their fleas in Los Angeles County, California.
Journal of clinical microbiology 1992;30(7):1758-62.
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1992: Sacci J B; Schriefer M E; Resau J H; Wirtz R A; Detolla L J; Markham R B; Azad A F
Mouse model for exoerythrocytic stages of Plasmodium falciparum malaria parasite.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):3701-5.
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1992: Azad A F; Sacci J B; Nelson W M; Dasch G A; Schmidtmann E T; Carl M
Genetic characterization and transovarial transmission of a typhus-like rickettsia found in cat fleas.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):43-6.
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1991: Schriefer M E; Sacci J B; Wirtz R A; Azad A F
Detection of polymerase chain reaction-amplified malarial DNA in infected blood and individual mosquitoes.
Experimental parasitology 1991;73(3):311-6.
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1991: Campbell T A; Zlotnick G W; Neubert T A; Sacci J B; Gottlieb M
Purification and characterization of the 3'-nucleotidase/nuclease from promastigotes of Leishmania donovani.
Molecular and biochemical parasitology 1991;47(1):109-17.
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1990: Sacci J B; Campbell T A; Gottlieb M
Leishmania donovani: regulated changes in the level of expression of the surface 3'-nucleotidase/nuclease.
Experimental parasitology 1990;71(2):158-68.
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1987: Anthony R L; Grogl M; Sacci J B; Ballou R W
Rapid detection of Leishmania amastigotes in fluid aspirates and biopsies of human tissues.
The American journal of tropical medicine and hygiene 1987;37(2):271-6.
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1987: Sacci J B; Christensen H A; Vasquez A; Anthony R L
Serodiagnosis of New World leishmaniasis by using a genus-specific antigen in enzyme linked immunosorbent assays.
Diagnostic microbiology and infectious disease 1987;6(3):229-38.
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1986: Williams K M; Sacci J B; Anthony R L
Characterization and quantitation of membrane antigens of New World Leishmania species by using monoclonal antibodies in Western blot and flow microfluorometric assays.
The Journal of protozoology 1986;33(4):490-7.
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1986: Williams K M; Sacci J B; Anthony R L
Flow cytometric analysis of the effects exerted by monoclonal antibodies on binding and uptake of Leishmania mexicana subsp. mexicana promastigotes by murine peritoneal macrophages.
Infection and immunity 1986;52(1):36-44.
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1986: Williams K M; Sacci J B; Anthony R L
Identification and recovery of Leishmania antigen displayed on the surface membrane of mouse peritoneal macrophages infected in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(5):1853-8.
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1985: Anthony R L; Williams K M; Sacci J B; Rubin D C
Subcellular and taxonomic specificity of monoclonal antibodies to New World Leishmania.
The American journal of tropical medicine and hygiene 1985;34(6):1085-94.
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1984: Pierce N F; Sacci J B; Alving C R; Richardson E C
Enhancement by lipid A of mucosal immunogenicity of liposome-associated cholera toxin.
Reviews of infectious diseases 1984;6(4):563-6.
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1984: Pierce N F; Sacci J B
Enhanced mucosal priming by cholera toxin and procholeragenoid with a lipoidal amine adjuvant (avridine) delivered in liposomes.
Infection and immunity 1984;44(2):469-73.
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1983: Pierce N F; Cray W C; Sacci J B; Craig J P; Germanier R; Fürer E
Oral immunization against experimental cholera: the role of antigen form and antigen combinations in evoking protection.
Annals of the New York Academy of Sciences 1983;409():724-33.
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1983: Pierce N F; Cray W C; Sacci J B; Craig J P; Germanier R; Fürer E
Procholeragenoid: a safe and effective antigen for oral immunization against experimental cholera.
Infection and immunity 1983;40(3):1112-8.
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1982: Pierce N F; Cray W C; Sacci J B
Oral immunization of dogs with purified cholera toxin, crude cholera toxin, or B subunit: evidence for synergistic protection by antitoxic and antibacterial mechanisms.
Infection and immunity 1982;37(2):687-94.
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