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George Sachs

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
33
Shin, Jai Moo
26
Scott, David
20
Melchers, Klaus
18
Vagin, Olga
15
Munson, Keith
13
Weeks, David
13
Weeks, David
12
Lambrecht, Nils
11
Helander, Herbert
11
Zeng, N
10
Walsh, John
10
Marcus, Elizabeth
9
Kang, T
7
Bayle, D
7
Wen, Yi

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Publications

TOP 3
Sachs George; Wen Yi; Scott David R
Gastric Infection by Helicobacter pylori.
Wen Yi; Feng Jing; Scott David R; Marcus Elizabeth A; Sachs George
The pH-responsive regulon of HP0244 (FlgS), the cytoplasmic histidine kinase of Helicobacter pylori.
Stengel Andreas; Goebel Miriam; Yakubov Iskandar; Wang Lixin; Witcher Derrick; Coskun Tamer; Taché Yvette; Sachs George; Lambrecht Nils W G
Identification and characterization of nesfatin-1 immunoreactivity in endocrine cell types of the rat gastric oxyntic mucosa.

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All Publications

2009: Sachs George; Wen Yi; Scott David R
Gastric Infection by Helicobacter pylori.
Current gastroenterology reports 2009;11(6):455-61.
2009: Wen Yi; Feng Jing; Scott David R; Marcus Elizabeth A; Sachs George
The pH-responsive regulon of HP0244 (FlgS), the cytoplasmic histidine kinase of Helicobacter pylori.
Journal of bacteriology 2009;191(2):449-60.
2009: Stengel Andreas; Goebel Miriam; Yakubov Iskandar; Wang Lixin; Witcher Derrick; Coskun Tamer; Taché Yvette; Sachs George; Lambrecht Nils W G
Identification and characterization of nesfatin-1 immunoreactivity in endocrine cell types of the rat gastric oxyntic mucosa.
Endocrinology 2009;150(1):232-8.
2009: Shin Jai Moo; Munson Keith; Vagin Olga; Sachs George
The gastric HK-ATPase: structure, function, and inhibition.
Pflügers Archiv : European journal of physiology 2009;457(3):609-22.
2008: Shin Jai Moo; Sachs George
Pharmacology of proton pump inhibitors.
Current gastroenterology reports 2008;10(6):528-34.
2008: Shin Jai Moo; Sachs George; Kraut Jeffrey A
Simple diagnostic tests to detect toxic alcohol intoxications.
Translational research : the journal of laboratory and clinical medicine 2008;152(4):194-201.
2008: Vagin Olga; Tokhtaeva Elmira; Yakubov Iskandar; Shevchenko Eugenia; Sachs George
Inverse correlation between the extent of N-glycan branching and intercellular adhesion in epithelia. Contribution of the Na,K-ATPase beta1 subunit.
The Journal of biological chemistry 2008;283(4):2192-202.
2008: Shin J M; Vagin O; Munson K; Kidd M; Modlin I M; Sachs G
Molecular mechanisms in therapy of acid-related diseases.
Cellular and molecular life sciences : CMLS 2008;65(2):264-81.
2007: Vagin Olga; Sachs George; Tokhtaeva Elmira
The roles of the Na,K-ATPase beta 1 subunit in pump sorting and epithelial integrity.
Journal of bioenergetics and biomembranes 2007;39(5-6):367-72.
2007: Zer Cindy; Sachs George; Shin Jai Moo
Identification of genomic targets downstream of p38 mitogen-activated protein kinase pathway mediating tumor necrosis factor-alpha signaling.
Physiological genomics 2007;31(2):343-51.
2007: Lambrecht Nils W G; Yakubov Iskandar; Sachs George
Fasting-induced changes in ECL cell gene expression.
Physiological genomics 2007;31(2):183-92.
2007: Sachs George; Shin Jai Moo; Vagin Olga; Lambrecht Nils; Yakubov Iskandar; Munson Keith
The gastric H,K ATPase as a drug target: past, present, and future.
Journal of clinical gastroenterology 2007;41 Suppl 2():S226-42.
2007: Munson Keith; Law Richard J; Sachs George
Analysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites.
Biochemistry 2007;46(18):5398-417.
2007: Scott David R; Marcus Elizabeth A; Wen Yi; Oh Jane; Sachs George
Gene expression in vivo shows that Helicobacter pylori colonizes an acidic niche on the gastric surface.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(17):7235-40.
2007: Wen Yi; Feng Jing; Scott David R; Marcus Elizabeth A; Sachs George
The HP0165-HP0166 two-component system (ArsRS) regulates acid-induced expression of HP1186 alpha-carbonic anhydrase in Helicobacter pylori by activating the pH-dependent promoter.
Journal of bacteriology 2007;189(6):2426-34.
2006: Vagin Olga; Tokhtaeva Elmira; Sachs George
The role of the beta1 subunit of the Na,K-ATPase and its glycosylation in cell-cell adhesion.
The Journal of biological chemistry 2006;281(51):39573-87.
2006: Sachs G; Shin J M; Howden C W
Review article: the clinical pharmacology of proton pump inhibitors.
Alimentary pharmacology & therapeutics 2006;23 Suppl 2():2-8.
2006: Shin Jai Moo; Sachs George
Gastric H,K-ATPase as a drug target.
Digestive diseases and sciences 2006;51(5):823-33.
2006: Wen Yi; Feng Jing; Scott David R; Marcus Elizabeth A; Sachs George
Involvement of the HP0165-HP0166 two-component system in expression of some acidic-pH-upregulated genes of Helicobacter pylori.
Journal of bacteriology 2006;188(5):1750-61.
2006: Shin Jai Moo; Homerin Michel; Domagala Florence; Ficheux Hervé; Sachs George
Characterization of the inhibitory activity of tenatoprazole on the gastric H+,K+ -ATPase in vitro and in vivo.
Biochemical pharmacology 2006;71(6):837-49.
2006: Lambrecht Nils W G; Yakubov Iskandar; Zer Cindy; Sachs George
Transcriptomes of purified gastric ECL and parietal cells: identification of a novel pathway regulating acid secretion.
Physiological genomics 2006;25(1):153-65.
2006: Sachs G; Kraut J A; Wen Y; Feng J; Scott D R
Urea transport in bacteria: acid acclimation by gastric Helicobacter spp.
The Journal of membrane biology 2006;212(2):71-82.
2005: Shin Jai Moo; Grundler Gerhard; Senn-Bilfinger Jörg; Simon Wolfgang Alexander; Sachs George
Functional consequences of the oligomeric form of the membrane-bound gastric H,K-ATPase.
Biochemistry 2005;44(49):16321-32.
2005: Sachs George; Weeks David L; Wen Yi; Marcus Elizabeth A; Scott David R; Melchers Klaus
Acid acclimation by Helicobacter pylori.
Physiology (Bethesda, Md.) 2005;20():429-38.
2005: Vagin Olga; Turdikulova Shahlo; Sachs George
Recombinant addition of N-glycosylation sites to the basolateral Na,K-ATPase beta1 subunit results in its clustering in caveolae and apical sorting in HGT-1 cells.
The Journal of biological chemistry 2005;280(52):43159-67.
2005: Mareninova Olga; Shin Jai Moo; Vagin Olga; Turdikulova Shahlo; Hallen Stefan; Sachs George
Topography of the membrane domain of the liver Na+-dependent bile acid transporter.
Biochemistry 2005;44(42):13702-12.
2005: Vagin Olga; Turdikulova Shahlo; Yakubov Iskandar; Sachs George
Use of the H,K-ATPase beta subunit to identify multiple sorting pathways for plasma membrane delivery in polarized cells.
The Journal of biological chemistry 2005;280(15):14741-54.
2005: Lambrecht Nils W G; Yakubov Iskandar; Scott David; Sachs George
Identification of the K efflux channel coupled to the gastric H-K-ATPase during acid secretion.
Physiological genomics 2005;21(1):81-91.
2005: Kraut Jeffrey A; Sachs George
Hartnup disorder: unraveling the mystery.
Trends in pharmacological sciences 2005;26(2):53-5.
2005: Marcus Elizabeth A; Moshfegh Amiel P; Sachs George; Scott David R
The periplasmic alpha-carbonic anhydrase activity of Helicobacter pylori is essential for acid acclimation.
Journal of bacteriology 2005;187(2):729-38.
2005: Oh David S; Lieu Sandy N; Yamaguchi Dean J; Tachiki Ken; Lambrecht Nils; Ohning Gordon V; Sachs George; Germano Patrizia M; Pisegna Joseph R
PACAP regulation of secretion and proliferation of pure populations of gastric ECL cells.
Journal of molecular neuroscience : MN 2005;26(1):85-97.
2004: Shin Jai Moo; Sachs George
Differences in binding properties of two proton pump inhibitors on the gastric H+,K+-ATPase in vivo.
Biochemical pharmacology 2004;68(11):2117-27.
2004: Vagin Olga; Turdikulova Shahlo; Sachs George
The H,K-ATPase beta subunit as a model to study the role of N-glycosylation in membrane trafficking and apical sorting.
The Journal of biological chemistry 2004;279(37):39026-34.
2004: Shin Jai Moo; Cho Young Moon; Sachs George
Chemistry of covalent inhibition of the gastric (H+, K+)-ATPase by proton pump inhibitors.
Journal of the American Chemical Society 2004;126(25):7800-11.
2004: Kim Nayoung; Marcus Elizabeth A; Wen Yi; Weeks David L; Scott David R; Jung Hyun Chae; Song In Sung; Sachs George
Genes of Helicobacter pylori regulated by attachment to AGS cells.
Infection and immunity 2004;72(4):2358-68.
2004: Sachs George; Shin Jai Moo
The basis of differentiation of PPIs.
Drugs of today (Barcelona, Spain : 1998) 2004;40 Suppl A():9-14.
2004: Weeks David L; Gushansky Gene; Scott David R; Sachs George
Mechanism of proton gating of a urea channel.
The Journal of biological chemistry 2004;279(11):9944-50.
2003: Sachs George
Physiology of the parietal cell and therapeutic implications.
Pharmacotherapy 2003;23(10 Pt 2):68S-73S.
2003: Wen Yi; Marcus Elizabeth A; Matrubutham Uday; Gleeson Martin A; Scott David R; Sachs George
Acid-adaptive genes of Helicobacter pylori.
Infection and immunity 2003;71(10):5921-39.
2003: Vagin O; Denevich S; Sachs G
Plasma membrane delivery of the gastric H,K-ATPase: the role of beta-subunit glycosylation.
American journal of physiology. Cell physiology 2003;285(4):C968-76.
2003: Vagin Olga; Munson Keith; Denevich Svetlana; Sachs George
Inhibition kinetics of the gastric H,K-ATPase by K-competitive inhibitor SCH28080 as a tool for investigating the luminal ion pathway.
Annals of the New York Academy of Sciences 2003;986():111-5.
2003: Munson Keith; Vagin Olga; Sachs George; Karlish Steve
Molecular modeling of SCH28080 binding to the gastric H,K-ATPase and MgATP interactions with SERCA- and Na,K-ATPases.
Annals of the New York Academy of Sciences 2003;986():106-10.
2003: Sachs G; Shin J M; Pratha V; Hogan D
Synthesis or rupture: duration of acid inhibition by proton pump inhibitors.
Drugs of today (Barcelona, Spain : 1998) 2003;39 Suppl A():11-4.
2003: Hong Wu; Sano Kouichi; Morimatsu Shinichi; Scott David R; Weeks David L; Sachs George; Goto Toshiyuki; Mohan Sharad; Harada Fumiue; Nakajima Norihito; Nakano Takashi
Medium pH-dependent redistribution of the urease of Helicobacter pylori.
Journal of medical microbiology 2003;52(Pt 3):211-6.
2003: Tatishchev Sergei; Abuladze Natalia; Pushkin Alexander; Newman Debra; Liu Weixin; Weeks David; Sachs George; Kurtz Ira
Identification of membrane topography of the electrogenic sodium bicarbonate cotransporter pNBC1 by in vitro transcription/translation.
Biochemistry 2003;42(3):755-65.
2003: Voland Petra; Weeks David L; Marcus Elizabeth A; Prinz Christian; Sachs George; Scott David
Interactions among the seven Helicobacter pylori proteins encoded by the urease gene cluster.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(1):G96-G106.
2003: Sachs George; Weeks David L; Melchers Klaus; Scott David R
The gastric biology of Helicobacter pylori.
Annual review of physiology 2003;65():349-69.
2002: Hallén S; Björquist A; Ostlund-Lindqvist A M; Sachs G
Identification of a region of the ileal-type sodium/bile acid cotransporter interacting with a competitive bile acid transport inhibitor.
Biochemistry 2002;41(50):14916-24.
2002: Sachs George; Shin Jai Moo; Vagin Olga; Munson Keith; Weeks David; Scott David R; Voland Petra
Current trends in the treatment of upper gastrointestinal disease.
Best practice & research. Clinical gastroenterology 2002;16(6):835-49.
2002: Shin Jai Moo; Sachs George
Restoration of acid secretion following treatment with proton pump inhibitors.
Gastroenterology 2002;123(5):1588-97.
2002: Kim Nayoung; Weeks David L; Shin Jai Moo; Scott David R; Young Mary K; Sachs George
Proteins released by Helicobacter pylori in vitro.
Journal of bacteriology 2002;184(22):6155-62.
2002: Vagin O; Denevich S; Munson K; Sachs G
SCH28080, a K+-competitive inhibitor of the gastric H,K-ATPase, binds near the M5-6 luminal loop, preventing K+ access to the ion binding domain.
Biochemistry 2002;41(42):12755-62.
2002: Patchornik Guy; Munson Keith; Goldshleger Rivka; Shainskaya Alla; Sachs George; Karlish Steven J D
The ATP-Mg2+ binding site and cytoplasmic domain interactions of Na+,K+-ATPase investigated with Fe2+-catalyzed oxidative cleavage and molecular modeling.
Biochemistry 2002;41(39):11740-9.
2002: Scott David R; Marcus Elizabeth A; Weeks David L; Sachs George
Mechanisms of acid resistance due to the urease system of Helicobacter pylori.
Gastroenterology 2002;123(1):187-95.
2002: Hallén S; Mareninova O; Brändén M; Sachs G
Organization of the membrane domain of the human liver sodium/bile acid cotransporter.
Biochemistry 2002;41(23):7253-66.
2002: Sachs George; Scott David; Weeks David; Melchers Klaus
The compartment buffered by the urease of Helicobacter pylori: cytoplasm or periplasm?
Trends in microbiology 2002;10(5):217-8; author reply 218-9.
2002: Voland P; Weeks D L; Vaira D; Prinz C; Sachs G
Specific identification of three low molecular weight membrane-associated antigens of Helicobacter pylori.
Alimentary pharmacology & therapeutics 2002;16(3):533-44.
2001: Shin J M; Goldshleger R; Munson K B; Sachs G; Karlish S J
Selective Fe2+-catalyzed oxidative cleavage of gastric H+,K+-ATPase: implications for the energy transduction mechanism of P-type cation pumps.
The Journal of biological chemistry 2001;276(51):48440-50.
2001: Sachs G; Scott D; Weeks D; Melchers K
The importance of the surface urease of Helicobacter pylori: fact or fiction?
Trends in microbiology 2001;9(11):532-4.
2001: Weeks D L; Sachs G
Sites of pH regulation of the urea channel of Helicobacter pylori.
Molecular microbiology 2001;40(6):1249-59.
2001: Vagin O; Munson K; Lambrecht N; Karlish S J; Sachs G
Mutational analysis of the K+-competitive inhibitor site of gastric H,K-ATPase.
Biochemistry 2001;40(25):7480-90.
2001: Sachs G
Improving on PPI-based therapy of GORD.
European journal of gastroenterology & hepatology 2001;13 Suppl 1():S35-41.
2000: Sachs G; Scott D; Weeks D; Melchers K
Gastric habitation by Helicobacter pylori: insights into acid adaptation.
Trends in pharmacological sciences 2000;21(11):413-6.
2000: Sachs G; Shin J M; Munson K; Vagin O; Lambrecht N; Scott D R; Weeks D L; Melchers K
Review article: the control of gastric acid and Helicobacter pylori eradication.
Alimentary pharmacology & therapeutics 2000;14(11):1383-401.
2000: Athmann C; Zeng N; Scott D R; Sachs G
Regulation of parietal cell calcium signaling in gastric glands.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(5):G1048-58.
2000: Hong W; Morimatsu S; Goto T; Sachs G; Scott D R; Weeks D L; Kohno T; Morita C; Nakano T; Fujioka Y; Sano K
Contrast-enhanced immunoelectron microscopy for Helicobacter pylori.
Journal of microbiological methods 2000;42(2):121-7.
2000: Athmann C; Zeng N; Kang T; Marcus E A; Scott D R; Rektorschek M; Buhmann A; Melchers K; Sachs G
Local pH elevation mediated by the intrabacterial urease of Helicobacter pylori cocultured with gastric cells.
The Journal of clinical investigation 2000;106(3):339-47.
2000: Scott D; Weeks D; Melchers K; Sachs G
UreI-mediated urea transport in Helicobacter pylori: an open and shut case?
Trends in microbiology 2000;8(8):348-9.
2000: Zizak M; Cavet M E; Bayle D; Tse C M; Hallen S; Sachs G; Donowitz M
Na(+)/H(+) exchanger NHE3 has 11 membrane spanning domains and a cleaved signal peptide: topology analysis using in vitro transcription/translation.
Biochemistry 2000;39(27):8102-12.
2000: Rektorschek M; Buhmann A; Weeks D; Schwan D; Bensch K W; Eskandari S; Scott D; Sachs G; Melchers K
Acid resistance of Helicobacter pylori depends on the UreI membrane protein and an inner membrane proton barrier.
Molecular microbiology 2000;36(1):141-52.
2000: Munson K B; Lambrecht N; Sachs G
Effects of mutations in M4 of the gastric H+,K+-ATPase on inhibition kinetics of SCH28080.
Biochemistry 2000;39(11):2997-3004.
2000: Lambrecht N; Munson K; Vagin O; Sachs G
Comparison of covalent with reversible inhibitor binding sites of the gastric H,K-ATPase by site-directed mutagenesis.
The Journal of biological chemistry 2000;275(6):4041-8.
2000: Wen Y; Sachs G; Athmann C
A novel lens epithelium gene, LEP503, is highly conserved in different vertebrate species and is developmentally regulated in postnatal rat lens.
Experimental eye research 2000;70(2):159-68.
2000: Scott D R; Marcus E A; Weeks D L; Lee A; Melchers K; Sachs G
Expression of the Helicobacter pylori ureI gene is required for acidic pH activation of cytoplasmic urease.
Infection and immunity 2000;68(2):470-7.
2000: Weeks D L; Eskandari S; Scott D R; Sachs G
A H+-gated urea channel: the link between Helicobacter pylori urease and gastric colonization.
Science (New York, N.Y.) 2000;287(5452):482-5.
2000: Munson K; Lambrecht N; Shin J M; Sachs G
Analysis of the membrane domain of the gastric H(+)/K(+)-ATPase.
The Journal of experimental biology 2000;203(Pt 1):161-70.
2000: Pisegna J R; Ohning G V; Athmann C; Zeng N; Walsh J H; Sachs G
Role of PACAP1 receptor in regulation of ECL cells and gastric acid secretion by pituitary adenylate cyclase activating peptide.
Annals of the New York Academy of Sciences 2000;921():233-41.
1999: Zeng N; Athmann C; Kang T; Walsh J H; Sachs G
Role of neuropeptide-sensitive L-type Ca(2+) channels in histamine release in gastric enterochromaffin-like cells.
The American journal of physiology 1999;277(6 Pt 1):G1268-80.
1999: Zeng N; Athmann C; Kang T; Lyu R M; Walsh J H; Ohning G V; Sachs G; Pisegna J R
PACAP type I receptor activation regulates ECL cells and gastric acid secretion.
The Journal of clinical investigation 1999;104(10):1383-91.
1999: Sachs G; Humphries T J
Rabeprazole: pharmacology, pharmacokinetics, and potential for drug interactions. Introduction.
Alimentary pharmacology & therapeutics 1999;13 Suppl 3():1-2.
1999: Hallén S; Brändén M; Dawson P A; Sachs G
Membrane insertion scanning of the human ileal sodium/bile acid co-transporter.
Biochemistry 1999;38(35):11379-88.
1999: Wen Y; Edelman J L; Kang T; Sachs G
Lipocortin V may function as a signaling protein for vascular endothelial growth factor receptor-2/Flk-1.
Biochemical and biophysical research communications 1999;258(3):713-21.
1999: Sachs G
Acid inhibition and gastroesophageal reflux disease.
The Yale journal of biology and medicine 1999;72(2-3):227-9.
1998: Zeng N; Kang T; Lyu R M; Wong H; Wen Y; Walsh J H; Sachs G; Pisegna J R
The pituitary adenylate cyclase activating polypeptide type 1 receptor (PAC1-R) is expressed on gastric ECL cells: evidence by immunocytochemistry and RT-PCR.
Annals of the New York Academy of Sciences 1998;865():147-56.
1998: Rektorschek M; Weeks D; Sachs G; Melchers K
Influence of pH on metabolism and urease activity of Helicobacter pylori.
Gastroenterology 1998;115(3):628-41.
1998: Melle-Milovanovic D; Lambrecht N; Sachs G; Shin J M
Structural aspects of the gastric H,K ATPase: the M5/M6 domain and alpha beta association.
Acta physiologica Scandinavica. Supplementum 1998;643():147-62.
1998: Melchers K; Herrmann L; Mauch F; Bayle D; Heuermann D; Weitzenegger T; Schuhmacher A; Sachs G; Haas R; Bode G; Bensch K; Schäfer K P
Properties and function of the P type ion pumps cloned from Helicobacter pylori.
Acta physiologica Scandinavica. Supplementum 1998;643():123-35.
1998: Zeng N; Kang T; Wen Y; Wong H; Walsh J; Sachs G
Galanin inhibition of enterochromaffin-like cell function.
Gastroenterology 1998;115(2):330-9.
1998: Scott D; Weeks D; Melchers K; Sachs G
The life and death of Helicobacter pylori.
Gut 1998;43 Suppl 1():S56-60.
1998: Lambrecht N; Corbett Z; Bayle D; Karlish S J; Sachs G
Identification of the site of inhibition by omeprazole of a alpha-beta fusion protein of the H,K-ATPase using site-directed mutagenesis.
The Journal of biological chemistry 1998;273(22):13719-28.
1998: Melle-Milovanovic D; Milovanovic M; Nagpal S; Sachs G; Shin J M
Regions of association between the alpha and the beta subunit of the gastric H,K-ATPase.
The Journal of biological chemistry 1998;273(18):11075-81.
1998: Wen Y; Edelman J L; Kang T; Zeng N; Sachs G
Two functional forms of vascular endothelial growth factor receptor-2/Flk-1 mRNA are expressed in normal rat retina.
The Journal of biological chemistry 1998;273(4):2090-7.
1998: Bayle D; Wängler S; Weitzenegger T; Steinhilber W; Volz J; Przybylski M; Schäfer K P; Sachs G; Melchers K
Properties of the P-type ATPases encoded by the copAP operons of Helicobacter pylori and Helicobacter felis.
Journal of bacteriology 1998;180(2):317-29.
1998: Scott D R; Weeks D; Hong C; Postius S; Melchers K; Sachs G
The role of internal urease in acid resistance of Helicobacter pylori.
Gastroenterology 1998;114(1):58-70.
1997: Shin J M; Besancon M; Bamberg K; Sachs G
Structural aspects of the gastric H,K ATPase.
Annals of the New York Academy of Sciences 1997;834():65-76.
1997: Besancon M; Simon A; Sachs G; Shin J M
Sites of reaction of the gastric H,K-ATPase with extracytoplasmic thiol reagents.
The Journal of biological chemistry 1997;272(36):22438-46.
1997: Bayle D; Weeks D; Sachs G
Identification of membrane insertion sequences of the rabbit gastric cholecystokinin-A receptor by in vitro translation.
The Journal of biological chemistry 1997;272(32):19697-707.
1997: Bayle D; Weeks D; Hallen S; Melchers K; Bamberg K; Sachs G
In vitro translation analysis of integral membrane proteins.
Journal of receptor and signal transduction research 1997;17(1-3):29-56.
1997: Sachs G
Proton pump inhibitors and acid-related diseases.
Pharmacotherapy 1997;17(1):22-37.
1997: Zeng N; Walsh J H; Kang T; Wu S V; Sachs G
Peptide YY inhibition of rat gastric enterochromaffin-like cell function.
Gastroenterology 1997;112(1):127-35.
1997: Sachs G; Meyer-Rosberg K; Scott D R; Melchers K; Shin J; Besancon M
Acid secretion and Helicobacter pylori.
Digestion 1997;58 Suppl 1():8-13.
1997: Sachs G; Zeng N; Prinz C
Physiology of isolated gastric endocrine cells.
Annual review of physiology 1997;59():243-56.
1996: Meyer-Rosberg K; Scott D R; Rex D; Melchers K; Sachs G
The effect of environmental pH on the proton motive force of Helicobacter pylori.
Gastroenterology 1996;111(4):886-900.
1996: Zeng N; Walsh J H; Kang T; Helander K G; Helander H F; Sachs G
Selective ligand-induced intracellular calcium changes in a population of rat isolated gastric endocrine cells.
Gastroenterology 1996;110(6):1835-46.
1996: Helander K G; Bamberg K; Sachs G; Melle D; Helander H F
Localization of mRNA for the muscarinic M1 receptor in rat stomach.
Biochimica et biophysica acta 1996;1312(2):158-62.
1996: Sachs G; Meyer-Rosberg K; Scott D R; Melchers K
Acid, protons and Helicobacter pylori.
The Yale journal of biology and medicine 1996;69(3):301-16.
1996: Loo D D; Sachs G; Prinz C
Potassium and chloride currents in rat gastric enterochromaffin-like cells.
The American journal of physiology 1996;270(5 Pt 1):E739-45.
1996: Melchers K; Weitzenegger T; Buhmann A; Steinhilber W; Sachs G; Schäfer K P
Cloning and membrane topology of a P type ATPase from Helicobacter pylori.
The Journal of biological chemistry 1996;271(1):446-57.
1995: Bayle D; Weeks D; Sachs G
The membrane topology of the rat sarcoplasmic and endoplasmic reticulum calcium ATPases by in vitro translation scanning.
The Journal of biological chemistry 1995;270(43):25678-84.
1995: Gedda K; Scott D; Besancon M; Lorentzon P; Sachs G
Turnover of the gastric H+,K(+)-adenosine triphosphatase alpha subunit and its effect on inhibition of rat gastric acid secretion.
Gastroenterology 1995;109(4):1134-41.
1995: Sachs G
Progress in therapy of ulcer disease.
Bildgebung = Imaging 1995;62 Suppl 1():76.
1995: Hirschowitz B I; Keeling D; Lewin M; Okabe S; Parsons M; Sewing K; Wallmark B; Sachs G
Pharmacological aspects of acid secretion.
Digestive diseases and sciences 1995;40(2 Suppl):3S-23S.
1995: Hersey S J; Sachs G
Gastric acid secretion.
Physiological reviews 1995;75(1):155-89.
1995: Sachs G; Shin J M; Briving C; Wallmark B; Hersey S
The pharmacology of the gastric acid pump: the H+,K+ ATPase.
Annual review of pharmacology and toxicology 1995;35():277-305.
1994: Scott D R; Besancon M; Sachs G; Helander H
Effects of antisecretory agents on parietal cell structure and H/K-ATPase levels in rabbit gastric mucosa in vivo.
Digestive diseases and sciences 1994;39(10):2118-26.
1994: Reuben M; Rising L; Prinz C; Hersey S; Sachs G
Cloning and expression of the rabbit gastric CCK-A receptor.
Biochimica et biophysica acta 1994;1219(2):321-7.
1994: Prinz C; Scott D R; Hurwitz D; Helander H F; Sachs G
Gastrin effects on isolated rat enterochromaffin-like cells in primary culture.
The American journal of physiology 1994;267(4 Pt 1):G663-75.
1994: Prinz C; Sachs G; Walsh J H; Coy D H; Wu S V
The somatostatin receptor subtype on rat enterochromaffinlike cells.
Gastroenterology 1994;107(4):1067-74.
1994: Sachs G; Prinz C; Loo D; Bamberg K; Besancon M; Shin J M
Gastric acid secretion: activation and inhibition.
The Yale journal of biology and medicine 1994;67(3-4):81-95.
1994: Tari A; Yamamoto G; Yonei Y; Sumii M; Sumii K; Haruma K; Kajiyama G; Wu V; Sachs G; Walsh J H
Effect of histamine on rat gastric H(+)-K(+)-ATPase alpha-subunit expression.
The American journal of physiology 1994;266(3 Pt 1):G444-50.
1994: Bamberg K; Nylander S; Helander K G; Lundberg L G; Sachs G; Helander H F
In situ hybridization of mRNA for the gastric H+,K(+)-ATPase in rat oxyntic mucosa.
Biochimica et biophysica acta 1994;1190(2):355-9.
1994: Shin J M; Besancon M; Prinz C; Simon A; Sachs G
Continuing development of acid pump inhibitors: site of action of pantoprazole.
Alimentary pharmacology & therapeutics 1994;8 Suppl 1():11-23.
1993: Scott D R; Hersey S J; Prinz C; Sachs G
Actions of antiulcer drugs.
Science (New York, N.Y.) 1993;262(5138):1453-4; author reply 1454-5.
1993: Tari A; Yamamoto G; Sumii K; Sumii M; Takehara Y; Haruma K; Kajiyama G; Wu V; Sachs G; Walsh J H
Role of histamine2 receptor in increased expression of rat gastric H(+)-K(+)-ATPase alpha-subunit induced by omeprazole.
The American journal of physiology 1993;265(4 Pt 1):G752-8.
1993: Prinz C; Kajimura M; Scott D R; Mercier F; Helander H F; Sachs G
Histamine secretion from rat enterochromaffinlike cells.
Gastroenterology 1993;105(2):449-61.
1993: Shin J M; Besancon M; Simon A; Sachs G
The site of action of pantoprazole in the gastric H+/K(+)-ATPase.
Biochimica et biophysica acta 1993;1148(2):223-33.
1993: Supplisson S; Loo D D; Sachs G
Whole-cell currents in isolated resting Necturus gastric oxynticopeptic cells.
The Journal of physiology 1993;463():57-82.
1993: Besancon M; Shin J M; Mercier F; Munson K; Miller M; Hersey S; Sachs G
Membrane topology and omeprazole labeling of the gastric H+,K(+)-adenosinetriphosphatase.
Biochemistry 1993;32(9):2345-55.
1993: Scott D R; Helander H F; Hersey S J; Sachs G
The site of acid secretion in the mammalian parietal cell.
Biochimica et biophysica acta 1993;1146(1):73-80.
1993: Sachs G; Shin J M; Besancon M; Prinz C
The continuing development of gastric acid pump inhibitors.
Alimentary pharmacology & therapeutics 1993;7 Suppl 1():4-12, discussion 29-31.
1992: Scott D R; Munson K; Modyanov N; Sachs G
Determination of the sidedness of the C-terminal region of the gastric H,K-ATPase alpha subunit.
Biochimica et biophysica acta 1992;1112(2):246-50.
1992: Prinz C; Kajimura M; Scott D; Helander H; Shin J; Besancon M; Bamberg K; Hersey S; Sachs G
Acid secretion and the H,K ATPase of stomach.
The Yale journal of biology and medicine 1992;65(6):577-96.
1992: Sachs G; Shin J M; Besancon M; Munson K; Hersey S
Topology and sites in the H,K-ATPase.
Annals of the New York Academy of Sciences 1992;671():204-16.
1992: Bayle D; Robert J C; Bamberg K; Benkouka F; Cheret A M; Lewin M J; Sachs G; Soumarmon A
Location of the cytoplasmic epitope for a K(+)-competitive antibody of the (H+,K+)-ATPase.
The Journal of biological chemistry 1992;267(27):19060-5.
1992: Sachs G; Besancon M; Shin J M; Mercier F; Munson K; Hersey S
Structural aspects of the gastric H,K-ATPase.
Journal of bioenergetics and biomembranes 1992;24(3):301-8.
1992: Bamberg K; Mercier F; Reuben M A; Kobayashi Y; Munson K B; Sachs G
cDNA cloning and membrane topology of the rabbit gastric H+/K(+)-ATPase alpha-subunit.
Biochimica et biophysica acta 1992;1131(1):69-77.
1992: Besancon M; Shin J M; Mercier F; Munson K; Rabon E; Hersey S; Sachs G
Chemomechanical coupling in the gastric H,K ATPase.
Acta physiologica Scandinavica. Supplementum 1992;607():77-88.
1992: Rabon E C; Sachs G; Leach C A; Keeling D
A K+ competitive, conformational probe of the H,K-ATPase.
Acta physiologica Scandinavica. Supplementum 1992;607():269-73.
1991: Tari A; Wu V; Sumii M; Sachs G; Walsh J H
Regulation of rat gastric H+/K(+)-ATPase alpha-subunit mRNA by omeprazole.
Biochimica et biophysica acta 1991;1129(1):49-56.
1991: Munson K B; Gutierrez C; Balaji V N; Ramnarayan K; Sachs G
Identification of an extracytoplasmic region of H+,K(+)-ATPase labeled by a K(+)-competitive photoaffinity inhibitor.
The Journal of biological chemistry 1991;266(28):18976-88.
1991: Supplisson S; Loo D D; Sachs G
Diversity of K+ channels in the basolateral membrane of resting Necturus oxyntic cells.
The Journal of membrane biology 1991;123(3):209-21.
1991: Rabon E; Sachs G; Bassilian S; Leach C; Keeling D
A K(+)-competitive fluorescent inhibitor of the H,K-ATPase.
The Journal of biological chemistry 1991;266(19):12395-401.
1991: Wilkes J M; Kajimura M; Scott D R; Hersey S J; Sachs G
Muscarinic responses of gastric parietal cells.
The Journal of membrane biology 1991;122(2):97-110.
1991: Hall K; Perez G; Sachs G; Rabon E
Identification of H+/K(+)-ATPase alpha,beta-heterodimers.
Biochimica et biophysica acta 1991;1077(2):173-9.
1991: Wilkes J M; Scott D R; Hersey S J; Sachs G
Second messengers in the gastric gland: a focus on calcium.
Scandinavian journal of gastroenterology. Supplement 1991;180():70-84.
1990: Sachs G; Munson K; Hall K; Hersey S J
Gastric H+,K(+)-ATPase as a therapeutic target in peptic ulcer disease.
Digestive diseases and sciences 1990;35(12):1537-44.
1990: Rabon E C; Bassilian S; Sachs G; Karlish S J
Conformational transitions of the H,K-ATPase studied with sodium ions as surrogates for protons.
The Journal of biological chemistry 1990;265(32):19594-9.
1990: Scott D; Reuben M; Zampighi G; Sachs G
Cell isolation and genotoxicity assessment in gastric mucosa.
Digestive diseases and sciences 1990;35(10):1217-25.
1990: Mendlein J; Ditmars M L; Sachs G
Calcium binding to the H+,K(+)-ATPase. Evidence for a divalent cation site that is occupied during the catalytic cycle.
The Journal of biological chemistry 1990;265(26):15590-8.
1990: Fryklund J; Gedda K; Scott D; Sachs G; Wallmark B
Coupling of H(+)-K(+)-ATPase activity and glucose oxidation in gastric glands.
The American journal of physiology 1990;258(5 Pt 1):G719-27.
1990: Mendlein J; Sachs G
Interaction of a K(+)-competitive inhibitor, a substituted imidazo[1,2a] pyridine, with the phospho- and dephosphoenzyme forms of H+, K(+)-ATPase.
The Journal of biological chemistry 1990;265(9):5030-6.
1990: Hall K; Perez G; Anderson D; Gutierrez C; Munson K; Hersey S J; Kaplan J H; Sachs G
Location of the carbohydrates present in the HK-ATPase vesicles isolated from hog gastric mucosa.
Biochemistry 1990;29(3):701-6.
1990: Mayer E A; Loo D D; Snape W J; Sachs G
The activation of calcium and calcium-activated potassium channels in mammalian colonic smooth muscle by substance P.
The Journal of physiology 1990;420():47-71.
1990: Wallmark B; Lorentzon P; Sachs G
The gastric H+,K(+)-ATPase.
Journal of internal medicine. Supplement 1990;732():3-8.
1990: Sachs G; Scott D; Reuben M
Omeprazole and the gastric mucosa.
Digestion 1990;47 Suppl 1():35-8.
1990: Sachs G; Scott D
Cell digestion and genotoxicity assessment in gastric mucosa.
Digestion 1990;47 Suppl 1():31-4.
1990: Sachs G; Rabon E; Karlish S J
Transport studies by optical methods.
Methods in enzymology 1990;191():469-79.
1989: Mendlein J; Sachs G
The substitution of calcium for magnesium in H+,K+-ATPase catalytic cycle. Evidence for two actions of divalent cations.
The Journal of biological chemistry 1989;264(31):18512-9.
1989: Sachs G; Munson K; Balaji V N; Aures-Fischer D; Hersey S J; Hall K
Functional domains of the gastric HK ATPase.
Journal of bioenergetics and biomembranes 1989;21(5):573-88.
1989: Hersey S J; Perez A; Matheravidathu S; Sachs G
Gastric H+-K+-ATPase in situ: evidence for compartmentalization.
The American journal of physiology 1989;257(4 Pt 1):G539-47.
1989: Helander H F; Anderson D; Helander K G; Smolka A; Sachs G
Immunocytochemical studies of gastric H+,K+-ATPase in the developing rat.
Scandinavian journal of gastroenterology 1989;24(7):863-9.
1989: Sachs G; Muallem S
Sites and mechanisms of Ca2+ movement in non-excitable cells.
Cell calcium 1989;10(5):265-73.
1989: Perez A; Blissard D; Sachs G; Hersey S J
Evidence for a chloride conductance in secretory membrane of parietal cells.
The American journal of physiology 1989;256(2 Pt 1):G299-305.
1989: Lorentzon P; Hersey S J; Wallmark B; Sachs G
Ion permeability and pump regulation.
Annals of the New York Academy of Sciences 1989;574():134-44.
1988: Malinowska D H; Sachs G; Cuppoletti J
Gastric H+ secretion: histamine (cAMP-mediated) activation of protein phosphorylation.
Biochimica et biophysica acta 1988;972(1):95-109.
1988: Hersey S J; Steiner L; Mendlein J; Rabon E; Sachs G
SCH28080 prevents omeprazole inhibition of the gastric H+/K+-ATPase.
Biochimica et biophysica acta 1988;956(1):49-57.
1988: Lorentzon P; Sachs G; Wallmark B
Inhibitory effects of cations on the gastric H+, K+ -ATPase. A potential-sensitive step in the K+ limb of the pump cycle.
The Journal of biological chemistry 1988;263(22):10705-10.
1988: Hersey S J; Steiner L; Matheravidathu S; Sachs G
Gastric H+-K+-ATPase in situ: relation to secretory state.
The American journal of physiology 1988;254(6 Pt 1):G856-63.
1988: Munson K B; Sachs G
Inactivation of H+,K+-ATPase by a K+-competitive photoaffinity inhibitor.
Biochemistry 1988;27(11):3932-8.
1988: Sachs G; Muallem S; Hersey S J
Passive and active transport in the parietal cell.
Comparative biochemistry and physiology. A, Comparative physiology 1988;90(4):727-31.
1988: Lorentzon P; Scott D; Hersey S; Wallmark B; Rabon E; Sachs G
The gastric H+,K+-ATPase.
Progress in clinical and biological research 1988;273():247-54.
1987: Wallmark B; Briving C; Fryklund J; Munson K; Jackson R; Mendlein J; Rabon E; Sachs G
Inhibition of gastric H+,K+-ATPase and acid secretion by SCH 28080, a substituted pyridyl(1,2a)imidazole.
The Journal of biological chemistry 1987;262(5):2077-84.
1987: Lorentzon P; Jackson R; Wallmark B; Sachs G
Inhibition of (H+ + K+)-ATPase by omeprazole in isolated gastric vesicles requires proton transport.
Biochimica et biophysica acta 1987;897(1):41-51.
1985: Rabon E; Gunther R D; Soumarmon A; Bassilian S; Lewin M; Sachs G
Solubilization and reconstitution of the gastric H,K-ATPase.
The Journal of biological chemistry 1985;260(18):10200-7.
1983: Smolka A; Helander H F; Sachs G
Monoclonal antibodies against gastric H+ + K+ ATPase.
The American journal of physiology 1983;245(4):G589-96.
1983: Malinowska D H; Cuppoletti J; Sachs G
Cl- requirement of acid secretion in isolated gastric glands.
The American journal of physiology 1983;245(4):G573-81.
1983: Rabon E; Cuppoletti J; Malinowska D; Smolka A; Helander H F; Mendlein J; Sachs G
Proton secretion by the gastric parietal cell.
The Journal of experimental biology 1983;106():119-33.
1983: Faller L D; Rabon E; Sachs G
Vanadate binding to the gastric H,K-ATPase and inhibition of the enzyme's catalytic and transport activities.
Biochemistry 1983;22(20):4676-85.
1983: Wallmark B; Sachs G; Mardh S; Fellenius E
Inhibition of gastric (H+ + K+)-ATPase by the substituted benzimidazole, picoprazole.
Biochimica et biophysica acta 1983;728(1):31-8.
1982: Rabon E; Sachs G; Mårdh S; Wallmark B
ATP/ADP exchange activity of gastric (H+ +K+)-ATPase.
Biochimica et biophysica acta 1982;688(2):515-24.
1982: Sachs G; Faller L D; Rabon E
Proton/hydroxyl transport in gastric and intestinal epithelia.
The Journal of membrane biology 1982;64(3):123-35.
1982: Faller L; Jackson R; Malinowska D; Mukidjam E; Rabon E; Saccomani G; Sachs G; Smolka A
Mechanistic aspects of gastric (H+ + K+)-ATPase.
Annals of the New York Academy of Sciences 1982;402():146-63.
1981: Saccomani G; Barcellona M L; Sachs G
Reactivity of gastric (H+ + K+)-ATPase to N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline.
The Journal of biological chemistry 1981;256(23):12405-10.
1981: Fellenius E; Berglindh T; Sachs G; Olbe L; Elander B; Sjöstrand S E; Wallmark B
Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+)ATPase.
Nature 1981;290(5802):159-61.
1981: Faller L D; Malinowska D H; Rabon E; Smolka A; Sachs G
Mechanistic studies of the gastric (H+ + K)-ATPase.
Progress in clinical and biological research 1981;73():153-74.
1980: Wallmark B; Stewart H B; Rabon E; Saccomani G; Sachs G
The catalytic cycle of gastric (H+ + K+)-ATPase.
The Journal of biological chemistry 1980;255(11):5313-9.
1980: Sachs G; Berglindh T; Rabon E; Wallmark B; Barcellona M L; Stewart H B; Saccomani G
The interaction of K+ with gastric parietal cells and gastric ATPase.
Annals of the New York Academy of Sciences 1980;358():118-37.
1980: Sachs G; Berglindh T; Rabon E; Stewart H B; Barcellona M L; Wallmark B; Saccomani G
Aspects of parietal cell biology: cells and vesicles.
Annals of the New York Academy of Sciences 1980;341():312-34.

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