FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Michael Sack

Research Profile

Procedures

Myocardial Ischemic Preconditioning

Living Beings

Anatomy

Physiology

Disorders

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Nisha Narayan; Ilsa I Rovira; Michael N Sack; Junhui Sun; Guang Tong; Guanghui Wang; Renee Wong; Fredrick W Alt; Ronen Borenstein; Liu Cao; Hwei-Ling Cheng; Maria M Fergusson; Marjan Gucek; In Hye Lee; Jie Liu; David Lombard; Elizabeth Murphy; TOREN FINKEL
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Michael N Sack; TOREN FINKEL
Mitochondrial metabolism, sirtuins, and aging.
Kye-Young Kim; Michael N Sack
Parkin in the regulation of fat uptake and mitochondrial biology: emerging links in the pathophysiology of Parkinson's disease.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Michael Sack (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Nisha Narayan; Ilsa I Rovira; Michael N Sack; Junhui Sun; Guang Tong; Guanghui Wang; Renee Wong; Fredrick W Alt; Ronen Borenstein; Liu Cao; Hwei-Ling Cheng; Maria M Fergusson; Marjan Gucek; In Hye Lee; Jie Liu; David Lombard; Elizabeth Murphy; TOREN FINKEL
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Nature 2012;492(7428):199-204.
2012: Michael N Sack; TOREN FINKEL
Mitochondrial metabolism, sirtuins, and aging.
Cold Spring Harbor perspectives in biology 2012;4(12):.
2012: Kye-Young Kim; Michael N Sack
Parkin in the regulation of fat uptake and mitochondrial biology: emerging links in the pathophysiology of Parkinson's disease.
Current opinion in lipidology 2012;23(3):201-5.
2012: Iain Scott; Bradley R Webster; Jian H Li; Michael N Sack
Identification of a molecular component of the mitochondrial acetyltransferase programme: a novel role for GCN5L1.
The Biochemical journal 2012;443(3):655-61.
2012: C Avila; R J Huang; K Y Kim; Mark Stevens; D Tripodi; Angel M Aponte; Michael N Sack
Platelet mitochondrial dysfunction is evident in type 2 diabetes in association with modifications of mitochondrial anti-oxidant stress proteins.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2012;120(4):248-51.
2011: Lisa Schwartz Longacre; Richard S. Vanderheide; Jakob Vinten-Johansen; Derek M Yellon; Andrew Arai; Christopher P Baines; Roberto Bolli; Eugene Braunwald; James Downey; Raymond J Gibbons; Roberta Anne Gottlieb; Gerd Heusch; Robert B Jennings; Robert A Kloner; David J Lefer; Robert M Mentzer; Elizabeth Murphy; Michel Ovize; Peipei Ping; Karin Przyklenk; Michael N Sack
New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop.
Circulation 2011;124(10):1172-9.
2011: Michael N Sack; Elizabeth Murphy
The role of comorbidities in cardioprotection.
Journal of cardiovascular pharmacology and therapeutics 2011;16(3-4):267-72.
2011: Joy McCarthy; Lionel Henry Opie; Michael N Sack; Amanda Lochner; M Faadiel Essop
PKCε promotes cardiac mitochondrial and metabolic adaptation to chronic hypobaric hypoxia by GSK3β inhibition.
Journal of cellular physiology 2011;226(9):2457-68.
2011: Zhongping Lu; Lance R Pohl; Angel M Aponte; Mohammed Bourdi; Yong Chen; Marjan Gucek; Jian H Li; David Lombard; Michael N Sack
SIRT3-dependent deacetylation exacerbates acetaminophen hepatotoxicity.
EMBO reports 2011;12(8):840-6.
2011: Ho Joong Sung; Wenzhe Ma; Matthew F Starost; Cory U Lago; Philip K Lim; Michael N Sack; Ju-Gyeong Kang; Ping-yuan Wang; PAUL HWANG
Ambient oxygen promotes tumorigenesis.
PloS one 2011;6(5):e19785.
2011: Hongjun Liu; Maria M Fergusson; J Julie Wu; Ilsa I Rovira; Jie Liu; Oksana Gavrilova; Teng Lu; Jianjun Bao; Donghe Han; Michael N Sack; TOREN FINKEL
Wnt signaling regulates hepatic metabolism.
Science signaling 2011;4(158):ra6.
2010: Michael N Sack
Mitochondrial Fe-S cluster biogenesis, frataxin and the modulation of susceptibility to drug-induced cardiomyopathy.
Aging 2010;2(11):754-5.
2010: Lydia Lacerda; Joy McCarthy; Shazia F K Mungly; Edward G Lynn; Michael N Sack; Lionel Henry Opie; Sandrine Lecour
TNFα protects cardiac mitochondria independently of its cell surface receptors.
Basic research in cardiology 2010;105(6):751-62.
2010: Jianjun Bao; Iain Scott; Zhongping Lu; Liyan Pang; Christopher C Dimond; David Gius; Michael N Sack
SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity.
Free radical biology & medicine 2010;49(7):1230-7.
2010: Edward G Lynn; Mark Stevens; Renee P Wong; Darin Carabenciov; Jeremy Jacobson; Elizabeth Murphy; Michael N Sack
Transient upregulation of PGC-1alpha diminishes cardiac ischemia tolerance via upregulation of ANT1.
Journal of molecular and cellular cardiology 2010;49(4):693-8.
2010: Jianjun Bao; Michael N Sack
Protein deacetylation by sirtuins: delineating a post-translational regulatory program responsive to nutrient and redox stressors.
Cellular and molecular life sciences : CMLS 2010;67(18):3073-87.
2010: Ines Pagel-Langenickel; Jianjun Bao; Liyan Pang; Michael N Sack
The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance.
Endocrine reviews 2010;31(1):25-51.
2009: Michael N Sack
Type 2 diabetes, mitochondrial biology and the heart.
Journal of molecular and cellular cardiology 2009;46(6):842-9.
2008: Britt N Fuglesteg; Naushaad Suleman; Crina Tiron; Tambuzai Kanhema; Lydia Lacerda; Thomas Andreasen; Michael N Sack; Anne K Jonassen; Ole D Mjøs; Lionel Henry Opie; Sandrine Lecour
Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion.
Basic research in cardiology 2008;103(5):444-53.
2008: Zhongping Lu; Michael N Sack
ATF-1 is a hypoxia-responsive transcriptional activator of skeletal muscle mitochondrial-uncoupling protein 3.
The Journal of biological chemistry 2008;283(34):23410-8.
2008: Ines Pagel-Langenickel; Jianjun Bao; Joshua J Joseph; Daniel R Schwartz; Benjamin S Mantell; Xiuli Xu; Nalini Raghavachari; Michael N Sack
PGC-1alpha integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscle.
The Journal of biological chemistry 2008;283(33):22464-72.
2008: Daniel R Schwartz; Michael N Sack
Targeting the mitochondria to augment myocardial protection.
Current opinion in pharmacology 2008;8(2):160-5.
2007: Ines Pagel-Langenickel; Daniel R Schwartz; Ross Arena; Diane C Minerbi; D Thor Johnson; Myron A Waclawiw; Richard O Cannon; Robert Balaban; Dorothy J Tripodi; Michael N Sack
A discordance in rosiglitazone mediated insulin sensitization and skeletal muscle mitochondrial content/activity in Type 2 diabetes mellitus.
American journal of physiology. Heart and circulatory physiology 2007;293(5):H2659-66.
2007: Edward G Lynn; Zhongping Lu; Diane Minerbi; Michael N Sack
The regulation, control, and consequences of mitochondrial oxygen utilization and disposition in the heart and skeletal muscle during hypoxia.
Antioxidants & redox signaling 2007;9(9):1353-61.
2007: Jan Minners; Dr L Lacerda; Derek M Yellon; Lionel Henry Opie; Christopher J McLeod; Michael N Sack
Diazoxide-induced respiratory inhibition - a putative mitochondrial K(ATP) channel independent mechanism of pharmacological preconditioning.
Molecular and cellular biochemistry 2007;294(1-2):11-8.
2006: Michael N Sack
Mitochondrial depolarization and the role of uncoupling proteins in ischemia tolerance.
Cardiovascular research 2006;72(2):210-9.
2006: Sandrine Lecour; Elizabeth van der Merwe; Lionel Henry Opie; Michael N Sack
Ceramide attenuates hypoxic cell death via reactive oxygen species signaling.
Journal of cardiovascular pharmacology 2006;47(1):158-63.
2005: Christopher J McLeod; Abdulhameed Aziz; Robert F Hoyt; J Philip McCoy; Michael N Sack
Uncoupling proteins 2 and 3 function in concert to augment tolerance to cardiac ischemia.
The Journal of biological chemistry 2005;280(39):33470-6.
2005: Christopher J McLeod; Ines Pagel; Michael N Sack
The mitochondrial biogenesis regulatory program in cardiac adaptation to ischemia--a putative target for therapeutic intervention.
Trends in cardiovascular medicine 2005;15(3):118-23.
2005: Joy McCarthy; Christopher J McLeod; Jan Minners; M Faadiel Essop; Peipei Ping; Michael N Sack
PKCepsilon activation augments cardiac mitochondrial respiratory post-anoxic reserve--a putative mechanism in PKCepsilon cardioprotection.
Journal of molecular and cellular cardiology 2005;38(4):697-700.
2005: Siyanda Makaula; Amanda Lochner; Sonia Genade; Michael N Sack; Moneeb M Awan; Lionel Henry Opie
H-89, a non-specific inhibitor of protein kinase A, promotes post-ischemic cardiac contractile recovery and reduces infarct size.
Journal of cardiovascular pharmacology 2005;45(4):341-7.
2004: Robert M Smith; Naushaad Suleman; Dr L Lacerda; Lionel Henry Opie; Shizuo Akira; Kenneth R Chien; Michael N Sack
Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning.
Cardiovascular research 2004;63(4):611-6.
2004: Christopher J McLeod; Anandhi P Jeyabalan; Jan Minners; Randall Clevenger; Robert F Hoyt; Michael N Sack
Delayed ischemic preconditioning activates nuclear-encoded electron-transfer-chain gene expression in parallel with enhanced postanoxic mitochondrial respiratory recovery.
Circulation 2004;110(5):534-9.
2004: Anne K Jonassen; Ole D Mjøs; Michael N Sack
p70s6 kinase is a functional target of insulin activated Akt cell-survival signaling.
Biochemical and biophysical research communications 2004;315(1):160-5.
2004: M Faadiel Essop; Peter Razeghi; Christopher J McLeod; Martin E Young; Heinrich Taegtmeyer; Michael N Sack
Hypoxia-induced decrease of UCP3 gene expression in rat heart parallels metabolic gene switching but fails to affect mitochondrial respiratory coupling.
Biochemical and biophysical research communications 2004;314(2):561-4.
2003: Sandrine Lecour; Michael N Sack; Lionel Henry Opie
[Sphingolipid signaling: a potential pathway for TNF-alpha induced preconditioning].
Annales de cardiologie et d'angéiologie 2003;52(6):363-9.
2003: Kholiswa Ngumbela; Michael N Sack; M Faadiel Essop
Counter-regulatory effects of incremental hypoxia on the transcription of a cardiac fatty acid oxidation enzyme-encoding gene.
Molecular and cellular biochemistry 2003;250(1-2):151-8.
2003: Jan Minners; Christopher J McLeod; Michael N Sack
Mitochondrial plasticity in classical ischemic preconditioning-moving beyond the mitochondrial KATP channel.
Cardiovascular research 2003;59(1):1-6.
2003: Michael N Sack; Derek M Yellon
Insulin therapy as an adjunct to reperfusion after acute coronary ischemia: a proposed direct myocardial cell survival effect independent of metabolic modulation.
Journal of the American College of Cardiology 2003;41(8):1404-7.
2002: Lionel Henry Opie; Michael N Sack
Metabolic plasticity and the promotion of cardiac protection in ischemia and ischemic preconditioning.
Journal of molecular and cellular cardiology 2002;34(9):1077-89.
2002: Robert M Smith; Naushaad Suleman; Joy McCarthy; Michael N Sack
Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha gene.
Cardiovascular research 2002;55(3):553-60.
2002: Robert M Smith; Sandrine Lecour; Michael N Sack
Innate immunity and cardiac preconditioning: a putative intrinsic cardioprotective program.
Cardiovascular research 2002;55(3):474-82.
2002: Sandrine Lecour; Robert M Smith; Brian Woodward; Lionel Henry Opie; Luc Rochette; Michael N Sack
Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotection.
Journal of molecular and cellular cardiology 2002;34(5):509-18.
2001: Anne K Jonassen; Michael N Sack; Ole D Mjøs; Derek M Yellon
Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling.
Circulation research 2001;89(12):1191-8.
2001: Jan Minners; Dr L Lacerda; Joy McCarthy; J J Meiring; Derek M Yellon; Michael N Sack
Ischemic and pharmacological preconditioning in Girardi cells and C2C12 myotubes induce mitochondrial uncoupling.
Circulation research 2001;89(9):787-92.
2001: Lionel Henry Opie; Michael N Sack
Enhanced angiotensin II activity in heart failure: reevaluation of the counterregulatory hypothesis of receptor subtypes.
Circulation research 2001;88(7):654-8.
2001: R M Smith; J McCarthy; Michael N Sack
TNF alpha is required for hypoxia-mediated right ventricular hypertrophy.
Molecular and cellular biochemistry 2001;219(1-2):139-43.
2000: Moneeb M Awan; Siyanda Makaula; S Forresti; Michael N Sack; Lionel Henry Opie
Mechanisms whereby glucose deprivation triggers metabolic preconditioning in the isolated rat heart.
Molecular and cellular biochemistry 2000;211(1-2):111-21.
2000: Jan Minners; E J van den Bos; Derek M Yellon; Herzl Schwalb; Lionel Henry Opie; Michael N Sack
Dinitrophenol, cyclosporin A, and trimetazidine modulate preconditioning in the isolated rat heart: support for a mitochondrial role in cardioprotection.
Cardiovascular research 2000;47(1):68-73.
2000: Anne K Jonassen; Bhawanjit K Brar; Ole D Mjøs; Michael N Sack; David S Latchman; Derek M Yellon
Insulin administered at reoxygenation exerts a cardioprotective effect in myocytes by a possible anti-apoptotic mechanism.
Journal of molecular and cellular cardiology 2000;32(5):757-64.
2000: Michael N Sack; L S Harrington; Anne K Jonassen; Ole D Mjøs; Derek M Yellon
Coordinate regulation of metabolic enzyme encoding genes during cardiac development and following carvedilol therapy in spontaneously hypertensive rats.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2000;14(1):31-9.
2000: Michael N Sack; Robert M Smith; Lionel Henry Opie
Tumor necrosis factor in myocardial hypertrophy and ischaemia--an anti-apoptotic perspective.
Cardiovascular research 2000;45(3):688-95.