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Yasuyuki Sadzuka

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
34
Sonobe, Takashi
18
Sugiyama, Tomomi
16
Hirota, Sadao
7
Nozawa, Yasuo
6
Sugiyama, Ikumi
6
Miyagishima, Atsuo
4
Miyamoto, Ken-ichi
4
Oku, Naoto
4
Sawanishi, Hiroyuki
3
Tsuruda, Tomoko
3
Hirano, Toru
3
Yamashita, Yasuyo
2
Umegaki, Keizo
1
Yoshioka, Hisashi
1
Ugajin, Takashi

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Publications

TOP 3
Sadzuka Yasuyuki; Matsuura Makoto; Sonobe Takashi
The effect of taurine, a novel biochemical modulator, on the antitumor activity of Doxorubicin.
Sugiyama Ikumi; Sonobe Takashi; Sadzuka Yasuyuki
Effect of hybridized liposome by novel modification with some polyethyleneglycol-lipids.
Sadzuka Yasuyuki; Iwasaki Fumiaki; Sugiyama Ikumi; Horiuchi Kentaro; Hirano Toru; Ozawa Hidechika; Kanayama Naohiro; Oku Naoto
Phototoxicity of coproporphyrin as a novel photodynamic therapy was enhanced by liposomalization.

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All Publications

2009: Sadzuka Yasuyuki; Matsuura Makoto; Sonobe Takashi
The effect of taurine, a novel biochemical modulator, on the antitumor activity of Doxorubicin.
Biological & pharmaceutical bulletin 2009;32(9):1584-7.
2009: Sugiyama Ikumi; Sonobe Takashi; Sadzuka Yasuyuki
Effect of hybridized liposome by novel modification with some polyethyleneglycol-lipids.
International journal of pharmaceutics 2009;372(1-2):177-83.
2008: Sadzuka Yasuyuki; Iwasaki Fumiaki; Sugiyama Ikumi; Horiuchi Kentaro; Hirano Toru; Ozawa Hidechika; Kanayama Naohiro; Oku Naoto
Phototoxicity of coproporphyrin as a novel photodynamic therapy was enhanced by liposomalization.
Toxicology letters 2008;182(1-3):110-4.
2008: Itoh Yoshiaki; Shimazu Akira; Sadzuka Yasuyuki; Sonobe Takashi; Itai Shigeru
Novel method for stratum corneum pore size determination using positron annihilation lifetime spectroscopy.
International journal of pharmaceutics 2008;358(1-2):91-5.
2008: Sadzuka Yasuyuki; Nakagawa Kouhei; Yoshioka Hisashi; Sonobe Takashi
A liposomal formulation study of 2,7-dichlorodihydrofluorescein for detection of reactive oxygen species.
International journal of pharmaceutics 2008;356(1-2):300-5.
2008: Nakamori Takahiko; Miyagishim Atsuo; Nozawa Yasuo; Sadzuka Yasuyuki; Sonobe Takashi
Influence of load on particle size distribution of lactose-crystalline cellulose mixed powder.
International journal of pharmaceutics 2008;354(1-2):255-9.
2008: Sadzuka Yasuyuki; Hatakeyama Haruna; Daimon Takashi; Sonobe Takashi
Screening of biochemical modulator by tumor cell permeability of doxorubicin.
International journal of pharmaceutics 2008;354(1-2):63-9.
2007: Sadzuka Yasuyuki; Iwasaki Fumiaki; Sugiyama Ikumi; Horiuchi Kentaro; Hirano Toru; Ozawa Hidechika; Kanayama Naohiro; Sonobe Takashi
Study on liposomalization of zinc-coproporphyrin I as a novel drug in photodynamic therapy.
International journal of pharmaceutics 2007;338(1-2):306-9.
2007: Sadzuka Yasuyuki; Sonobe Takashi
Anserine induced advantage effects on the antitumor activity of doxorubicin.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(6):985-9.
2007: Sugiyama Ikumi; Sadzuka Yasuyuki
Characterization of novel mixed polyethyleneglycol modified liposomes.
Biological & pharmaceutical bulletin 2007;30(1):208-11.
2006: Sadzuka Yasuyuki; Tokutomi Koji; Iwasaki Fumiaki; Sugiyama Ikumi; Hirano Toru; Konno Hiroyuki; Oku Naoto; Sonobe Takashi
The phototoxicity of photofrin was enhanced by PEGylated liposome in vitro.
Cancer letters 2006;241(1):42-8.
2006: Sadzuka Yasuyuki; Sugiyama Ikumi; Tsuruda Tomoko; Sonobe Takashi
Characterization and cytotoxicity of mixed polyethyleneglycol modified liposomes containing doxorubicin.
International journal of pharmaceutics 2006;312(1-2):83-9.
2006: Kamiya Seitaro; Nozawa Yasuo; Miyagishima Astuo; Kurita Takurou; Sadzuka Yasuyuki; Sonobe Takashi
Physical characteristics of freeze-dried griseofulvin-lipids nanoparticles.
Chemical & pharmaceutical bulletin 2006;54(2):181-4.
2006: Sadzuka Yasuyuki; Sugiyama Tomomi; Nagamine Makiko; Umegaki Keizo; Sonobe Takashi
Efficacy of theanine is connected with theanine metabolism by any enzyme, not only drug metabolizing enzymes.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(2):286-92.
2005: Sadzuka Yasuyuki; Takabe Hiroyuki; Sonobe Takashi
Liposomalization of SN-38 as active metabolite of CPT-11.
Journal of controlled release : official journal of the Controlled Release Society 2005;108(2-3):453-9.
2005: Sadzuka Yasuyuki; Inoue Chieko; Hirooka Saho; Sugiyama Tomomi; Umegaki Keizo; Sonobe Takashi
Effects of theanine on alcohol metabolism and hepatic toxicity.
Biological & pharmaceutical bulletin 2005;28(9):1702-6.
2005: Suzuki Kazuyuki; Yano Tomohiro; Sadzuka Yasuyuki; Sugiyama Tomomi; Seki Taichiro; Asano Ryuji
Restoration of connexin 43 by Bowman-Birk protease inhibitor in M5076 bearing mice.
Oncology reports 2005;13(6):1247-50.
2005: Shimizu K; Asai T; Fuse C; Sadzuka Y; Sonobe T; Ogino K; Taki T; Tanaka T; Oku N
Applicability of anti-neovascular therapy to drug-resistant tumor: suppression of drug-resistant P388 tumor growth with neovessel-targeted liposomal adriamycin.
International journal of pharmaceutics 2005;296(1-2):133-41.
2005: Aoshima Hiroyuki; Miyagisnima Atsuo; Nozawa Yasuo; Sadzuka Yasuyuki; Sonobe Takashi
Glycerin fatty acid esters as a new lubricant of tablets.
International journal of pharmaceutics 2005;293(1-2):25-34.
2005: Sadzuka Yasuyuki; Tsuruda Tomoko; Sonobe Takashi
[Characterization and cytotoxicity of mixed PEG-DSG modified liposomes]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2005;125(1):149-57.
2004: Maeda Noriyuki; Takeuchi Yoshito; Takada Miki; Sadzuka Yasuyuki; Namba Yukihiro; Oku Naoto
Anti-neovascular therapy by use of tumor neovasculature-targeted long-circulating liposome.
Journal of controlled release : official journal of the Controlled Release Society 2004;100(1):41-52.
2004: Sugiyama Tomomi; Sadzuka Yasuyuki
Theanine, a specific glutamate derivative in green tea, reduces the adverse reactions of doxorubicin by changing the glutathione level.
Cancer letters 2004;212(2):177-84.
2004: Sadzuka Yasuyuki; Sugiyama Tomomi; Suzuki Hirokazu; Sawanishi Hiroyuki; Miyamoto Ken-Ichi
Increased effects of MPDAX, a novel xanthine derivative, on antitumor activity of doxorubicin.
Toxicology letters 2004;150(3):341-9.
2004: Kurita Takurou; Miyagishima Atsuo; Nozawa Yasuo; Sadzuka Yasuyuki; Sonobe Takashi
A dosage design of mitomycin C tablets containing finely powdered green tea.
International journal of pharmaceutics 2004;275(1-2):279-83.
2004: Ishida Tatsuhiro; Ichikawa Takako; Ichihara Masako; Sadzuka Yasuyuki; Kiwada Hiroshi
Effect of the physicochemical properties of initially injected liposomes on the clearance of subsequently injected PEGylated liposomes in mice.
Journal of controlled release : official journal of the Controlled Release Society 2004;95(3):403-12.
2004: Kondo Masami; Asai Tomohiro; Katanasaka Yasufumi; Sadzuka Yasuyuki; Tsukada Hideo; Ogino Koichi; Taki Takao; Baba Kazuhiko; Oku Naoto
Anti-neovascular therapy by liposomal drug targeted to membrane type-1 matrix metalloproteinase.
International journal of cancer. Journal international du cancer 2004;108(2):301-6.
2003: Sugiyama Tomomi; Sadzuka Yasuyuki
Theanine and glutamate transporter inhibitors enhance the antitumor efficacy of chemotherapeutic agents.
Biochimica et biophysica acta 2003;1653(2):47-59.
2003: Igarashi Akira; Konno Hiroyuki; Tanaka Tatsuo; Nakamura Satoshi; Sadzuka Yasuyuki; Hirano Toru; Fujise Yutaka
Liposomal photofrin enhances therapeutic efficacy of photodynamic therapy against the human gastric cancer.
Toxicology letters 2003;145(2):133-41.
2003: Sadzuka Yasuyuki; Nakade Akiko; Tsuruda Tomoko; Sonobe Takashi
Study on the characterization of mixed polyethyleneglycol modified liposomes containing doxorubicin.
Journal of controlled release : official journal of the Controlled Release Society 2003;91(3):271-80.
2003: Sadzuka Yasuyuki; Kishi Kaori; Hirota Sadao; Sonobe Takashi
Effect of polyethyleneglycol (PEG) chain on cell uptake of PEG-modified liposomes.
Journal of liposome research 2003;13(2):157-72.
2002: Sadzuka Yasuyuki; Yamashita Yasuyo; Sonobe Takashi
Effects of glutamate transporter inhibitors on the antitumor activity of doxorubicin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(12):3943-7.
2002: Saito Masataka; Ugajin Takashi; Nozawa Yasuo; Sadzuka Yasuyuki; Miyagishima Atsuo; Sonobe Takashi
Preparation and dissolution characteristics of griseofulvin solid dispersions with saccharides.
International journal of pharmaceutics 2002;249(1-2):71-9.
2002: Sadzuka Yasuyuki; Yamashita Yasuyo; Kishimoto Shuichi; Fukushima Shoji; Takeuchi Yoshikazu; Sonobe Takashi
[Glutamate transporter mediated increase of antitumor activity by theanine, an amino acid in green tea]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2002;122(11):995-9.
2002: Sadzuka Yasuyuki; Egawa Youichi; Sawanishi Hiroyuki; Miyamoto Ken-ichi; Sonobe Takashi
Effects of xanthine derivatives on the influx and efflux of doxorubicin in P388 and DOX-resistant P388 leukemia cells.
Toxicology letters 2002;135(1-2):137-44.
2002: Sadzuka Yasuyuki; Nakade Akiko; Hirama Rieko; Miyagishima Atsuo; Nozawa Yasuo; Hirota Sadao; Sonobe Takashi
Effects of mixed polyethyleneglycol modification on fixed aqueous layer thickness and antitumor activity of doxorubicin containing liposome.
International journal of pharmaceutics 2002;238(1-2):171-80.
2002: Sadzuka Yasuyuki; Yamashita Yasuyo; Sugiyama Tomomi; Sonobe Takashi
Effect of dihydrokainate on the antitumor activity of doxorubicin.
Cancer letters 2002;179(2):157-63.
2002: Nagai Katsuhito; Nagasawa Kazuki; Sadzuka Yasuyuki; Tsujimoto Masayuki; Takara Kohji; Ohnishi Noriaki; Yokoyama Teruyoshi; Fujimoto Sadaki
Relationships between the in vitro cytotoxicity and transport characteristics of pirarubicin and doxorubicin in M5076 ovarian sarcoma cells, and comparison with those in Ehrlich ascites carcinoma cells.
Cancer chemotherapy and pharmacology 2002;49(3):244-50.
2002: Sadzuka Yasuyuki; Hirama Rieko; Sonobe Takashi
Effects of intraperitoneal administration of liposomes and methods of preparing liposomes for local therapy.
Toxicology letters 2002;126(2):83-90.
2001: Sadzuka Y; Sugiyama T; Suzuki T; Sonobe T
Enhancement of the activity of doxorubicin by inhibition of glutamate transporter.
Toxicology letters 2001;123(2-3):159-67.
2001: Sugiyama T; Sadzuka Y; Tanaka K; Sonobe T
Inhibition of glutamate transporter by theanine enhances the therapeutic efficacy of doxorubicin.
Toxicology letters 2001;121(2):89-96.
2000: Sadzuka Y; Sugiyama T; Sonobe T
Improvement of idarubicin induced antitumor activity and bone marrow suppression by theanine, a component of tea.
Cancer letters 2000;158(2):119-24.
2000: Shimada K; Matsuo S; Sadzuka Y; Miyagishima A; Nozawa Y; Hirota S; Sonobe T
Determination of incorporated amounts of poly(ethylene glycol)-derivatized lipids in liposomes for the physicochemical characterization of stealth liposomes.
International journal of pharmaceutics 2000;203(1-2):255-63.
2000: Sadzuka Y; Hirota S; Sonobe T
Intraperitoneal administration of doxorubicin encapsulating liposomes against peritoneal dissemination.
Toxicology letters 2000;116(1-2):51-9.
2000: Sadzuka Y; Egawa Y; Sugiyama T; Sawanishi H; Miyamoto K; Sonobe T
Effects of 1-methyl-3-propyl-7-butylxanthine (MPBX) on idarubicin-induced antitumor activity and bone marrow suppression.
Japanese journal of cancer research : Gann 2000;91(6):651-7.
2000: Sadzuka Y; Sugiyama T; Sonobe T
Efficacies of tea components on doxorubicin induced antitumor activity and reversal of multidrug resistance.
Toxicology letters 2000;114(1-3):155-62.
1999: Sugiyama T; Sadzuka Y; Nagasawa K; Ohnishi N; Yokoyama T; Sonobe T
Membrane transport and antitumor activity of pirarubicin, and comparison with those of doxorubicin.
Japanese journal of cancer research : Gann 1999;90(7):775-80.
1999: Sadzuka Y; Sugiyama T; Sawanishi H; Miyamoto K
Enhanced efficacy of 1-methyl-3-propyl-7-butylxanthine on the antitumor activity of doxorubicin against doxorubicin-resistant P388 leukemia.
Cancer letters 1999;138(1-2):5-11.
1999: Sadzuka Y; Hirotsu S; Hirota S
Effective irinotecan (CPT-11)-containing liposomes: intraliposomal conversion to the active metabolite SN-38.
Japanese journal of cancer research : Gann 1999;90(2):226-32.
1999: Sugiyama T; Sadzuka Y
Combination of theanine with doxorubicin inhibits hepatic metastasis of M5076 ovarian sarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(2):413-6.
1998: Sugiyama T; Sadzuka Y
Enhancing effects of green tea components on the antitumor activity of adriamycin against M5076 ovarian sarcoma.
Cancer letters 1998;133(1):19-26.
1998: Sadzuka Y; Hirota S
Does the amount of an antitumor agent entrapped in liposomes influence its tissue distribution and cell uptake?
Cancer letters 1998;131(2):163-70.
1998: Sadzuka Y; Hirotsu S; Hirota S
Effect of liposomalization on the antitumor activity, side-effects and tissue distribution of CPT-11.
Cancer letters 1998;127(1-2):99-106.
1998: Sadzuka Y; Iwazaki A; Hirota S
[Effects of methylxanthine derivatives on antitumor activity and toxic side effect of adriamycin induced by inhibition of DNA biosynthesis]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1998;118(5):179-87.
1998: Sadzuka Y; Iwazaki A; Sugiyama T; Sawanishi T; Miyamoto K
1-Methyl-3-propyl-7-butylxanthine, a novel biochemical modulator, enhances therapeutic efficacy of adriamycin.
Japanese journal of cancer research : Gann 1998;89(2):228-33.
1998: Sadzuka Y; Sugiyama T; Hirota S
Modulation of cancer chemotherapy by green tea.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(1):153-6.
1997: Sadzuka Y; Sugiyama T; Shimoi K; Kinae N; Hirota S
Protective effect of flavonoids on doxorubicin-induced cardiotoxicity.
Toxicology letters 1997;92(1):1-7.
1997: Sadzuka Y; Hirota S
Effect of CPT-11 on lipid peroxide level in mouse tissues.
Japanese journal of cancer research : Gann 1997;88(5):512-6.
1997: Sadzuka Y; Nakai S; Miyagishima A; Nozawa Y; Hirota S
Effects of administered route on tissue distribution and antitumor activity of polyethyleneglycol-coated liposomes containing adriamycin.
Cancer letters 1997;111(1-2):77-86.
1996: Sadzuka Y; Sugiyama T; Miyagishima A; Nozawa Y; Hirota S
The effects of theanine, as a novel biochemical modulator, on the antitumor activity of adriamycin.
Cancer letters 1996;105(2):203-9.
1995: Sadzuka Y; Iwazaki A; Miyagishima A; Nozawa Y; Hirota S
Effects of methylxanthine derivatives on adriamycin concentration and antitumor activity.
Japanese journal of cancer research : Gann 1995;86(6):594-9.
1995: Sadzuka Y; Mochizuki E; Takino Y
Mechanism of caffeine modulation of the antitumor activity of adriamycin.
Toxicology letters 1995;75(1-3):39-49.
1995: Sadzuka Y; Mochizuki E; Iwazaki A; Hirota S; Takino Y
Caffeine enhances adriamycin antitumor activity in Ehrlich ascites carcinoma-bearing mice.
Biological & pharmaceutical bulletin 1995;18(1):159-61.
1995: Shimada K; Miyagishima A; Sadzuka Y; Nozawa Y; Mochizuki Y; Ohshima H; Hirota S
Determination of the thickness of the fixed aqueous layer around polyethyleneglycol-coated liposomes.
Journal of drug targeting 1995;3(4):283-9.
1995: Sadzuka Y; Nakai S; Miyagishima A; Nozawa Y; Hirota S
The effect of dose on the distribution of adriamycin encapsulated in polyethyleneglycol-coated liposomes.
Journal of drug targeting 1995;3(1):31-7.
1994: Sadzuka Y; Shimizu Y; Takino Y; Hirota S
Protection against cisplatin-induced nephrotoxicity in the rat by inducers and an inhibitor of glutathione S-transferase.
Biochemical pharmacology 1994;48(3):453-9.
1994: Sadzuka Y; Shimizu Y; Takino Y
Role of glutathione S-transferase isoenzymes in cisplatin-induced nephrotoxicity in the rat.
Toxicology letters 1994;70(2):211-22.
1993: Sadzuka Y; Mochizuki E; Takino Y
Caffeine modulates the antitumor activity and toxic side effects of adriamycin.
Japanese journal of cancer research : Gann 1993;84(3):348-53.
1992: Sadzuka Y; Shoji T; Takino Y
Mechanism of the increase in lipid peroxide induced by cisplatin in the kidneys of rats.
Toxicology letters 1992;62(2-3):293-300.
1992: Sadzuka Y; Takino Y
Effect of seasonal variation on lipid peroxide level and glutathione peroxidase activity in the mouse before and after adriamycin administration.
Toxicology letters 1992;61(1):49-56.
1992: Sadzuka Y; Takino Y
Effect of tetrahydropyranyladriamycin (THP-ADR) and 4'-epiadriamycin (4'-epi-ADR) on lipid peroxide levels in mice.
Chemical & pharmaceutical bulletin 1992;40(5):1329-31.
1992: Sadzuka Y; Shoji T; Takino Y
Effect of cisplatin on the activities of enzymes which protect against lipid peroxidation.
Biochemical pharmacology 1992;43(8):1872-5.
1991: Sadzuka Y; Shoji T; Takino Y
Change of lipid peroxide levels in rat tissues after cisplatin administration.
Toxicology letters 1991;57(2):159-66.

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