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Sheikh Arshad Saeed

Research Profile

Physiology

Chemicals & Drugs

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Publications

TOP 3
Ishfaq A Bukhari; RAFEEQ ALAM KHAN; Anwar H Gilani; Sagheer Ahmed; Sheikh Arshad Saeed
Analgesic, anti-inflammatory and anti-platelet activities of the methanolic extract of Acacia modesta leaves.
Fatima Shad Kaneez; Sheikh Arshad Saeed
Investigating GABA and its function in platelets as compared to neurons.
Sheikh Arshad Saeed; Naheed Anwar; Khalid M Khan; Noorjehan Sarfraz
Effect of chronic treatment with a cyclooxygenase inhibitor on reproductive parameters in male rat.

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All Publications

2010: Ishfaq A Bukhari; RAFEEQ ALAM KHAN; Anwar H Gilani; Sagheer Ahmed; Sheikh Arshad Saeed
Analgesic, anti-inflammatory and anti-platelet activities of the methanolic extract of Acacia modesta leaves.
Inflammopharmacology 2010;18(4):187-96.
2009: Fatima Shad Kaneez; Sheikh Arshad Saeed
Investigating GABA and its function in platelets as compared to neurons.
Platelets 2009;20(5):328-33.
2009: Sheikh Arshad Saeed; Naheed Anwar; Khalid M Khan; Noorjehan Sarfraz
Effect of chronic treatment with a cyclooxygenase inhibitor on reproductive parameters in male rat.
Journal of Ayub Medical College, Abbottabad : JAMC 2009;21(3):66-71.
2008: Anwarul Hassan Gilani; Malik Hassan Mehmood; Khalid H Janbaz; Arif-ullah Khan; Sheikh Arshad Saeed
Ethnopharmacological studies on antispasmodic and antiplatelet activities of Ficus carica.
Journal of ethnopharmacology 2008;119(1):1-5.
2008: Sheikh Arshad Saeed; Ali Hyder Zaidi
Inflammatory bowel disease: treatment postulates and future prospects.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2008;18(3):197.
2007: Kaneez Fatima Shad; Sheikh Arshad Saeed
The metabolism of serotonin in neuronal cells in culture and platelets.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2007;183(3):411-6.
2007: Sheikh Arshad Saeed; Kaneez Fatima Shad; Taimur Saleem; Faisal Javed; Muhammad Umair Khan
Some new prospects in the understanding of the molecular basis of the pathogenesis of stroke.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2007;182(1):1-10.
2007: Sheikh Arshad Saeed; Kaneez Fatima Shad; Shabana Usman Simjee
Dual inhibition of cyclooxygenase and lipoxygenase enzymes by human cerebrospinal fluid.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 2007;178(4):560-4.
2007: Sheikh Arshad Saeed; John Dennis Connor; Javeria Quadri; Shumaila Tasneem; Sagheer Ahmed; Muhammad Ahmed Mesaik; M Iqbal Choudhary
Inhibitors of phosphatidylinositide 3-kinase: effects on reactive oxygen species and platelet aggregation.
Pharmacological reports : PR 2007;59(2):238-43.
2007: Sheikh Arshad Saeed; Nabeel Ahmad; Sagheer Ahmed
Dual inhibition of cyclooxygenase and lipoxygenase by human haptoglobin: its polymorphism and relation to hemoglobin binding.
Biochemical and biophysical research communications 2007;353(4):915-20.
2007: Shabana Usman Simjee; huma jawed; Javeria Quadri; Sheikh Arshad Saeed
Quantitative gait analysis as a method to assess mechanical hyperalgesia modulated by disease-modifying antirheumatoid drugs in the adjuvant-induced arthritic rat.
Arthritis research & therapy 2007;9(5):R91.
2006: Sheikh Arshad Saeed; Sagheer Ahmed
Anti-ischemic effects of nimesulide, a cyclooxygenase-2 inhibitor on the ischemic model of rabbit induced by isoproterenol.
Archives of pharmacal research 2006;29(11):977-83.
2006: Sheikh Arshad Saeed; Sagheer Ahmed
Role of cyclooxygenase-2 in myocardial infarction and ischaemia.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2006;16(5):324-8.
2005: Rahmat Ali; Saad Ali; Sheikh Arshad Saeed; Afrasyab Khan; Madiha Mustafa; Sohaib Aleem
Latest approaches to the diagnosis and management of food allergies in children.
JPMA. The Journal of the Pakistan Medical Association 2005;55(10):458-62.
2005: Sheikh Arshad Saeed; Muhammad Anwar Waqar; Akbar Jaleel Zubairi; Hadi Bhurgri; Abdullah Khan; Saqib Ali Sikander Gowani; Saima N Waqar; M Iqbal Choudhary; Saima Jalil; Ali Hyder Zaidi; Iffat Ara
Myocardial ischaemia and reperfusion injury: reactive oxygen species and the role of neutrophil.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2005;15(8):507-14.
2005: Sheikh Arshad Saeed; Ramesh Kumar Tanwani
Neonatal factors predisposing to atopy.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2005;15(5):315.
2005: Idrees Farooq Butt; Sheikh Arshad Saeed; Saima N Waqar; Muhammad Aslam
Synergistic interaction of epinephrine and calcium ionophore in platelet aggregation.
Journal of Ayub Medical College, Abbottabad : JAMC 2005;17(2):1-5.
2005: Sheikh Arshad Saeed
Hyposensitization.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2005;15(4):250.
2005: Sheikh Arshad Saeed; Sagheer Ahmed
New aspects of cyclooxygenase-2 inhibition in myocardial infarction and ischaemia.
Research communications in molecular pathology and pharmacology 2005;117-118():167-78.
2004: Sheikh Arshad Saeed; Huma Rasheed; Faisal A Wahed Fecto; Mohammad Ilyas Achakzai; Rahmat Ali; John Dennis Connor; Anwar-ul-Hassan Gilani
Signaling mechanisms mediated by G-protein coupled receptors in human platelets.
Acta pharmacologica Sinica 2004;25(7):887-92.
2004: Huma Rasheed; Sheikh Arshad Saeed
Involvement of thromboxane A2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation.
Experimental & molecular medicine 2004;36(3):220-5.
2004: Sheikh Arshad Saeed; Rahmat Ali; Syed Sohail Ali; Nabeel Ahmad; Abdul Basit; Mian Zainul Sajadeen Urfy
A closer look at food allergy and intolerance.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2004;14(6):376-80.
2003: Sheikh Arshad Saeed; Huma Rasheed; Anwar-ul-Hassan Gilani
Synergism interaction between arachidonic acid by 5-hydroxytryptamine in human platelet aggregation is mediated through multiple signalling pathways.
Acta pharmacologica Sinica 2003;24(10):958-64.
2003: Sheikh Arshad Saeed; Huma Rasheed
Calcium-dependent synergistic interaction of platelet activating factor and epinephrine in human platelet aggregation.
Acta pharmacologica Sinica 2003;24(1):31-6.
2002: Sheikh Arshad Saeed; Anwarul Hassan Gilani; Huma Rasheed; FN Bhatti; Mehnaz Atiq; A Qureshi; R Jafary; John Dennis Connor
Plasma from rheumatoid patients taking low dose methotrexate enhances platelet aggregation.
Research communications in molecular pathology and pharmacology 2002;111(1-4):69-76.
2001: BH Shah; Huma Rasheed; I H Rahman; A H Shariff; F L Khan; H B Rahman; S Hanif; Sheikh Arshad Saeed
Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.
Experimental & molecular medicine 2001;33(4):226-33.
2001: John Dennis Connor; Huma Rasheed; Anwarul Hassan Gilani; M Cheema; Zulfiqar H Rizvi; Sheikh Arshad Saeed
Second messengers in platelet aggregation evoked by serotonin and A23187, a calcium ionophore.
Life sciences 2001;69(23):2759-64.
2001: Sheikh Arshad Saeed; John Dennis Connor; Huma Rasheed; Anwarul Hassan Gilani; S Lodhi; S S Ali; S Rashid; E Khan; BH Shah
Wortmannin inhibits platelet aggregation produced by interaction of gamma-aminobutyric acid and the calcium tonophore, A23187.
Research communications in molecular pathology and pharmacology 2001;109(1-2):87-93.
2001: Sheikh Arshad Saeed; Huma Rasheed; Anwarul Hassan Gilani; A Hashmi; BH Shah
An investigation of cyclooxygenase and signalling inhibitors on 5-hydroxytryptamine- and epinephrine-induced platelet activation.
Proceedings of the Western Pharmacology Society 2001;44():159-62.
1999: BH Shah; Z Nawaz; S A Pertani; A Roomi; H Mahmood; Sheikh Arshad Saeed; Anwarul Hassan Gilani
Inhibitory effect of curcumin, a food spice from turmeric, on platelet-activating factor- and arachidonic acid-mediated platelet aggregation through inhibition of thromboxane formation and Ca2+ signaling.
Biochemical pharmacology 1999;58(7):1167-72.
1999: BH Shah; A Siddiqui; K A Qureshi; M Khan; S Rafi; V A Ujan; M Y Yakoob; Y Yaqub; Huma Rasheed; Sheikh Arshad Saeed
Co-activation of Gi and Gq proteins exerts synergistic effect on human platelet aggregation through activation of phospholipase C and Ca2+ signalling pathways.
Experimental & molecular medicine 1999;31(1):42-6.
1999: M N Afzal; Sheikh Arshad Saeed; BH Shah
Atherosclerosis and plaque rupture: an update.
JPMA. The Journal of the Pakistan Medical Association 1999;49(2):37-43.
1998: Sheikh Arshad Saeed; Anwarul Hassan Gilani; B H Sultan; R M Karim; BH Shah
Myocardial ischaemia and infarction in isoprenaline-treated rabbits: role of cyclooxygenases.
Biochemical Society transactions 1998;26(4):S342.
1998: BH Shah; Z Nawaz; S S Virani; I Q Ali; Sheikh Arshad Saeed; Anwarul Hassan Gilani
The inhibitory effect of cinchonine on human platelet aggregation due to blockade of calcium influx.
Biochemical pharmacology 1998;56(8):955-60.
1998: Sheikh Arshad Saeed; M N Afzal; BH Shah
Dual effects of nimesulide, a COX-2 inhibitor, in human platelets.
Life sciences 1998;63(20):1835-41.
1997: Sheikh Arshad Saeed; F Mahmood; BH Shah; Anwarul Hassan Gilani
The inhibition of prostaglandin biosynthesis by human haptoglobin and its relationship with haemoglobin binding.
Biochemical Society transactions 1997;25(4):S618.
1997: BH Shah; Sheikh Arshad Saeed; G Shamim; Z Nawaz; Anwarul Hassan Gilani
Role of phosphatidylinositol 3-kinase in human platelet aggregation.
Biochemical Society transactions 1997;25(4):S600.
1997: BH Shah; B Safdar; S S Virani; Z Nawaz; Sheikh Arshad Saeed; Anwarul Hassan Gilani
The antiplatelet aggregatory activity of Acacia nilotica is due to blockade of calcium influx through membrane calcium channels.
General pharmacology 1997;29(2):251-5.
1997: Sheikh Arshad Saeed; Anwarul Hassan Gilani; R U Majoo; BH Shah
Anti-thrombotic and anti-inflammatory activities of protopine.
Pharmacological research : the official journal of the Italian Pharmacological Society 1997;36(1):1-7.
1997: Sheikh Arshad Saeed; R A Memon; Anwarul Hassan Gilani; BH Shah
Effects of lipoproteins on cyclo-oxygenase and lipoxygenase pathways in human platelets.
JPMA. The Journal of the Pakistan Medical Association 1997;47(3):84-8.
1997: BH Shah; Sheikh Arshad Saeed; F Rashid; Anwarul Hassan Gilani
Dopamine potentiation of calcium ionophore, A-23187-induced platelet aggregation.
Advances in experimental medicine and biology 1997;407():537-40.
1997: Sheikh Arshad Saeed; BH Shah
Diversity of agonist-mediated signal transduction pathways in human platelets.
Advances in experimental medicine and biology 1997;407():531-5.
1996: Sabira Begum; S B Usmani; Bina S Siddiqui; Sheikh Arshad Saeed; S Farnaz; K A Khan; S A Khan; S M Khalid; A Zia
Chemistry and biological activity of a tryptamine and beta-carboline series of bases.
Arzneimittel-Forschung 1996;46(12):1163-8.
1996: BH Shah; G Shamim; S Khan; Sheikh Arshad Saeed
Protein kinase C inhibitor, chelerythrine, potentiates the adrenaline-mediated aggregation of human platelets through calcium influx.
Biochemistry and molecular biology international 1996;38(6):1135-41.
1995: Sheikh Arshad Saeed; G Shamim; R U Simjee; Anwarul Hassan Gilani
Eugenol: a dual inhibitor of platelet-activating factor and arachidonic acid metabolism.
Phytomedicine : international journal of phytotherapy and phytopharmacology 1995;2(1):23-8.
1995: R A Memon; Sheikh Arshad Saeed; Abdul Jabbar; A Jafri; Anwarul Hassan Gilani; S Saleem; H Akbani
Altered platelet activating factor metabolism in insulin dependent diabetes mellitus.
JPMA. The Journal of the Pakistan Medical Association 1995;45(5):122-5.
1994: Sheikh Arshad Saeed; N Ali; S Saleem
Differential effects of anti-asthmatic drugs on arachidonic acid and platelet-activating factor.
Biochemical Society transactions 1994;22(4):443S.
1994: Sheikh Arshad Saeed; Anwarul Hassan Gilani
Antithrombotic activity of clove oil.
JPMA. The Journal of the Pakistan Medical Association 1994;44(5):112-5.
1993: Sheikh Arshad Saeed; R U Simjee; F Mahmood; N Sultana
Rhazimine from Rhazya stricta: a dual inhibitor of arachidonic acid metabolism and platelet activating factor-induced platelet aggregation.
Planta medica 1993;59(6):566-8.
1993: Sheikh Arshad Saeed; S Farnaz; R U Simjee; A Malik
Triterpenes and B-sitosterol from piper betle: isolation, antiplatelet and anti-inflammatory effects.
Biochemical Society transactions 1993;21(4):462S.
1993: Sheikh Arshad Saeed; R U Simjee; S Farnaz; Anwarul Hassan Gilani; S Siddiqui; Bina S Siddiqui; Sabira Begum; Shaheen Faizi; A Zia
Inhibition of platelet aggregation and arachidonic acid metabolism by B-carboline alkaloids.
Biochemical Society transactions 1993;21(4):461S.
1993: Sheikh Arshad Saeed; M H Javed; G Ashraf
Modulation of cyclic AMP-dependent protein kinase activity by drugs affecting human platelet aggregation.
Biochemical Society transactions 1993;21(4):430S.
1993: Sheikh Arshad Saeed; R U Simjee; F Mahmood; N N Rahman
Dual inhibition of platelet-activating factor and arachidonic acid metabolism by ajmaline and effect on carrageenan-induced rat paw oedema.
The Journal of pharmacy and pharmacology 1993;45(8):715-9.
1992: Anwarul Hassan Gilani; K Aftab; Sheikh Arshad Saeed; A Suria
Effect of harmalol on blood pressure in anaesthetized rats.
Biochemical Society transactions 1992;20(4):359S.
1992: Sheikh Arshad Saeed; R U Simjee; Anwarul Hassan Gilani; S Siddiqui; Rubeena Saleem; Shaheen Faizi; Bina S Siddiqui; S Farnaz
8-Hydroxyquinoline and its derivatives: potential inhibitors of platelet aggregation.
Biochemical Society transactions 1992;20(4):357S.
1991: Sheikh Arshad Saeed; T R Boyde
Lactate dehydrogenase isoenzymes from human heart: separation by preparative gel electrophoresis; and a crystalline preparation of isoenzyme--1.
Biochemical Society transactions 1991;19(2):219S.
1991: Sheikh Arshad Saeed; T R Boyde
Separation of ferritin dimer, trimer and tetramer by preparative polyacrylamide gel electrophoresis and their identification by electron microscopy.
Biochemical Society transactions 1991;19(2):218S.
1991: Sheikh Arshad Saeed; F Mahmood; A Naqvi; M H Jafary
Inhibitory effect of oral ketotifen on ex vivo platelet activating factor-induced platelet aggregation.
Agents and actions. Supplements 1991;34():351-7.
1990: Anwarul Hassan Gilani; Sheikh Arshad Saeed
A comparative study of the effects of local anaesthetics on platelet aggregation.
Biochemical Society transactions 1990;18(2):288-9.
1990: Anwarul Hassan Gilani; Sheikh Arshad Saeed; S Q Husnain; A Suria
Effect of histamine receptor blockers on human platelet aggregation.
Biochemical Society transactions 1990;18(2):287-8.
1988: Sheikh Arshad Saeed; S J Karimi; A Suria
Differential effects of dimethyl sulfoxide on human platelet aggregation and arachidonic acid metabolism.
Biochemical medicine and metabolic biology 1988;40(2):143-50.
1988: A Suria; R Nasreen; Sheikh Arshad Saeed
GABA involvement in naloxone induced reversal of respiratory paralysis produced by thiopental.
Life sciences 1988;42(6):643-50.
1987: Sheikh Arshad Saeed; A Suria
Ability of human plasma to inhibit prostaglandin F2 alpha in asthma.
Biochemical medicine and metabolic biology 1987;38(2):235-9.
1986: Sheikh Arshad Saeed; A Suria
Prostaglandins, menstruation, and menstrual disorders.
JPMA. The Journal of the Pakistan Medical Association 1986;36(5):120-6.
1985: Sheikh Arshad Saeed; A Suria
Activity of endogenous inhibitor(s) of platelet aggregation in plasma of normal males, females and pregnant women.
JPMA. The Journal of the Pakistan Medical Association 1985;35(7):217-20.
1985: Sheikh Arshad Saeed; A Suria
Endogenous inhibitor (s) of platelet aggregation.
JPMA. The Journal of the Pakistan Medical Association 1985;35(2):41-4.
1984: Sheikh Arshad Saeed; A Suria
Bio-availability of drugs.
JPMA. The Journal of the Pakistan Medical Association 1984;34(10):322-5.