Walter Birchmeier

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Zhang Yuhang; Tomann Philip; Andl Thomas; Gallant Natalie M; Huelsken Joerg; Jerchow Boris; Birchmeier Walter; Paus Ralf; Piccolo Stefano; Mikkola Marja L; Morrisey Edward E; Overbeek Paul A; Scheidereit Claus; Millar Sarah E; Schmidt-Ullrich Ruth
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction.
Fritzmann Johannes; Morkel Markus; Besser Daniel; Budczies Jan; Kosel Frauke; Brembeck Felix H; Stein Ulrike; Fichtner Iduna; Schlag Peter M; Birchmeier Walter
A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Klaus Alexandra; Birchmeier Walter
Developmental signaling in myocardial progenitor cells: a comprehensive view of Bmp- and Wnt/beta-catenin signaling.

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2009: Zhang Yuhang; Tomann Philip; Andl Thomas; Gallant Natalie M; Huelsken Joerg; Jerchow Boris; Birchmeier Walter; Paus Ralf; Piccolo Stefano; Mikkola Marja L; Morrisey Edward E; Overbeek Paul A; Scheidereit Claus; Millar Sarah E; Schmidt-Ullrich Ruth
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction.
Developmental cell 2009;17(1):49-61.
2009: Fritzmann Johannes; Morkel Markus; Besser Daniel; Budczies Jan; Kosel Frauke; Brembeck Felix H; Stein Ulrike; Fichtner Iduna; Schlag Peter M; Birchmeier Walter
A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Gastroenterology 2009;137(1):165-75.
2009: Klaus Alexandra; Birchmeier Walter
Developmental signaling in myocardial progenitor cells: a comprehensive view of Bmp- and Wnt/beta-catenin signaling.
Pediatric cardiology 2009;30(5):609-16.
2009: Stein Ulrike; Walther Wolfgang; Arlt Franziska; Schwabe Holger; Smith Janice; Fichtner Iduna; Birchmeier Walter; Schlag Peter M
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
Nature medicine 2009;15(1):59-67.
2008: Hellmuth Klaus; Grosskopf Stefanie; Lum Ching Tung; Würtele Martin; Röder Nadine; von Kries Jens Peter; Rosario Marta; Rademann Jörg; Birchmeier Walter
Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(20):7275-80.
2008: Klaus Alexandra; Birchmeier Walter
Wnt signalling and its impact on development and cancer.
Nature reviews. Cancer 2008;8(5):387-98.
2008: Malanchi Ilaria; Peinado Hector; Kassen Deepika; Hussenet Thomas; Metzger Daniel; Chambon Pierre; Huber Marcel; Hohl Daniel; Cano Amparo; Birchmeier Walter; Huelsken Joerg
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.
Nature 2008;452(7187):650-3.
2008: Jeannet Grégoire; Scheller Marina; Scarpellino Léonardo; Duboux Stéphane; Gardiol Noemie; Back Jonathan; Kuttler Fabien; Malanchi Ilaria; Birchmeier Walter; Leutz Achim; Huelsken Joerg; Held Werner
Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.
Blood 2008;111(1):142-9.
2007: Schaeper Ute; Vogel Regina; Chmielowiec Jolanta; Huelsken Joerg; Rosario Marta; Birchmeier Walter
Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(39):15376-81.
2007: Rosário Marta; Franke Renate; Bednarski Christien; Birchmeier Walter
The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42.
The Journal of cell biology 2007;178(3):503-16.
2007: Baurand Anthony; Zelarayan Laura; Betney Russell; Gehrke Christina; Dunger Sandra; Noack Claudia; Busjahn Andreas; Huelsken Joerg; Taketo Makoto Mark; Birchmeier Walter; Dietz Rainer; Bergmann Martin W
Beta-catenin downregulation is required for adaptive cardiac remodeling.
Circulation research 2007;100(9):1353-62.
2007: Hosking Catherine Rose; Ulloa Fausto; Hogan Catherine; Ferber Emma C; Figueroa Angélica; Gevaert Kris; Birchmeier Walter; Briscoe James; Fujita Yasuyuki
The transcriptional repressor Glis2 is a novel binding partner for p120 catenin.
Molecular biology of the cell 2007;18(5):1918-27.
2007: Chmielowiec Jolanta; Borowiak Malgorzata; Morkel Markus; Stradal Theresia; Munz Barbara; Werner Sabine; Wehland Jürgen; Birchmeier Carmen; Birchmeier Walter
c-Met is essential for wound healing in the skin.
The Journal of cell biology 2007;177(1):151-62.
2007: Faraldo Marisa M; Teulière Jérôme; Deugnier Marie-Ange; Birchmeier Walter; Huelsken Joerg; Thiery Jean Paul; Cano Amparo; Glukhova Marina A
beta-Catenin regulates P-cadherin expression in mammary basal epithelial cells.
FEBS letters 2007;581(5):831-6.
2007: Zechner Dietmar; Müller Thomas; Wende Hagen; Walther Ingrid; Taketo Makoto M; Crenshaw E Bryan; Treier Mathias; Birchmeier Walter; Birchmeier Carmen
Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.
Developmental biology 2007;303(1):181-90.
2006: Moeller Heinz; Jenny Andreas; Schaeffer Hans-Joerg; Schwarz-Romond Thomas; Mlodzik Marek; Hammerschmidt Matthias; Birchmeier Walter
Diversin regulates heart formation and gastrulation movements in development.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(43):15900-5.
2006: Scheller Marina; Huelsken Joerg; Rosenbauer Frank; Taketo Makoto M; Birchmeier Walter; Tenen Daniel G; Leutz Achim
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
Nature immunology 2006;7(10):1037-47.
2006: MacRae Calum A; Birchmeier Walter; Thierfelder Ludwig
Arrhythmogenic right ventricular cardiomyopathy: moving toward mechanism.
The Journal of clinical investigation 2006;116(7):1825-8.
2006: Hadjihannas Michel V; Brückner Martina; Jerchow Boris; Birchmeier Walter; Dietmaier Wolfgang; Behrens Jürgen
Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(28):10747-52.
2006: Brembeck Felix H; Rosário Marta; Birchmeier Walter
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin.
Current opinion in genetics & development 2006;16(1):51-9.
2005: Stelzl Ulrich; Worm Uwe; Lalowski Maciej; Haenig Christian; Brembeck Felix H; Goehler Heike; Stroedicke Martin; Zenkner Martina; Schoenherr Anke; Koeppen Susanne; Timm Jan; Mintzlaff Sascha; Abraham Claudia; Bock Nicole; Kietzmann Silvia; Goedde Astrid; Toksöz Engin; Droege Anja; Krobitsch Sylvia; Korn Bernhard; Birchmeier Walter; Lehrach Hans; Wanker Erich E
A human protein-protein interaction network: a resource for annotating the proteome.
Cell 2005;122(6):957-68.
2005: Shu Weiguo; Guttentag Susan; Wang Zhishan; Andl Thomas; Ballard Philip; Lu Min Min; Piccolo Stefano; Birchmeier Walter; Whitsett Jeffrey A; Millar Sarah E; Morrisey Edward E
Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung.
Developmental biology 2005;283(1):226-39.
2005: Birchmeier Walter
Cell adhesion and signal transduction in cancer. Conference on cadherins, catenins and cancer.
EMBO reports 2005;6(5):413-7.
2005: Yu Hsiao-Man Ivy; Jerchow Boris; Sheu Tzong-Jen; Liu Bo; Costantini Frank; Puzas J Edward; Birchmeier Walter; Hsu Wei
The role of Axin2 in calvarial morphogenesis and craniosynostosis.
Development (Cambridge, England) 2005;132(8):1995-2005.
2004: Schuetz Gunnar; Rosário Marta; Grimm Jan; Boeckers Tobias M; Gundelfinger Eckart D; Birchmeier Walter
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells.
The Journal of cell biology 2004;167(5):945-52.
2004: Gerull Brenda; Heuser Arnd; Wichter Thomas; Paul Matthias; Basson Craig T; McDermott Deborah A; Lerman Bruce B; Markowitz Steve M; Ellinor Patrick T; MacRae Calum A; Peters Stefan; Grossmann Katja S; Drenckhahn Jörg; Michely Beate; Sasse-Klaassen Sabine; Birchmeier Walter; Dietz Rainer; Breithardt Günter; Schulze-Bahr Eric; Thierfelder Ludwig
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Nature genetics 2004;36(11):1162-4.
2004: Grossmann Katja S; Grund Christine; Huelsken Joerg; Behrend Martin; Erdmann Bettina; Franke Werner W; Birchmeier Walter
Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.
The Journal of cell biology 2004;167(1):149-60.
2004: Teulière J; Faraldo M M; Shtutman M; Birchmeier W; Huelsken J; Thiery J P; Glukhova M A
beta-catenin-dependent and -independent effects of DeltaN-plakoglobin on epidermal growth and differentiation.
Molecular and cellular biology 2004;24(19):8649-61.
2004: Brembeck Felix H; Schwarz-Romond Thomas; Bakkers Jeroen; Wilhelm Sabine; Hammerschmidt Matthias; Birchmeier Walter
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Genes & development 2004;18(18):2225-30.
2004: Hogan Catherine; Serpente Norberto; Cogram Patricia; Hosking Catherine Rose; Bialucha Carl Uli; Feller Stephan Michael; Braga Vania M M; Birchmeier Walter; Fujita Yasuyuki
Rap1 regulates the formation of E-cadherin-based cell-cell contacts.
Molecular and cellular biology 2004;24(15):6690-700.
2004: Rosário Marta; Birchmeier Walter
Making tubes: step by step.
Developmental cell 2004;7(1):3-5.
2004: Lamothe Betty; Yamada Masashi; Schaeper Ute; Birchmeier Walter; Lax Irit; Schlessinger Joseph
The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway.
Molecular and cellular biology 2004;24(13):5657-66.
2003: Birchmeier Carmen; Birchmeier Walter; Gherardi Ermanno; Vande Woude George F
Met, metastasis, motility and more.
Nature reviews. Molecular cell biology 2003;4(12):915-25.
2003: Morkel Markus; Huelsken Joerg; Wakamiya Maki; Ding Jixiang; van de Wetering Marc; Clevers Hans; Taketo Makoto M; Behringer Richard R; Shen Michael M; Birchmeier Walter
Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation.
Development (Cambridge, England) 2003;130(25):6283-94.
2003: Xu Youyuan; Banerjee Daliya; Huelsken Joerg; Birchmeier Walter; Sen Jyoti Misra
Deletion of beta-catenin impairs T cell development.
Nature immunology 2003;4(12):1177-82.
2003: Bamji Shernaz X; Shimazu Kazuhiro; Kimes Nikole; Huelsken Joerg; Birchmeier Walter; Lu Bai; Reichardt Louis F
Role of beta-catenin in synaptic vesicle localization and presynaptic assembly.
Neuron 2003;40(4):719-31.
2003: Mucenski Michael L; Wert Susan E; Nation Jennifer M; Loudy David E; Huelsken Joerg; Birchmeier Walter; Morrisey Edward E; Whitsett Jeffrey A
beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis.
The Journal of biological chemistry 2003;278(41):40231-8.
2003: Soshnikova Natalia; Zechner Dietmar; Huelsken Joerg; Mishina Yuji; Behringer Richard R; Taketo Makoto M; Crenshaw E Bryan; Birchmeier Walter
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.
Genes & development 2003;17(16):1963-8.
2003: Zechner Dietmar; Fujita Yasuyuki; Hülsken Jörg; Müller Thomas; Walther Ingrid; Taketo Makoto M; Crenshaw E Bryan; Birchmeier Walter; Birchmeier Carmen
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system.
Developmental biology 2003;258(2):406-18.
2003: Rosário Marta; Birchmeier Walter
How to make tubes: signaling by the Met receptor tyrosine kinase.
Trends in cell biology 2003;13(6):328-35.
2002: Schwarz-Romond Thomas; Asbrand Christian; Bakkers Jeroen; Kühl Michael; Schaeffer Hans-Joerg; Huelsken Jörg; Behrens Jürgen; Hammerschmidt Matthias; Birchmeier Walter
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling.
Genes & development 2002;16(16):2073-84.
2002: Kurz Steffen M; Diebold Sandra S; Hieronymus Thomas; Gust Tatjana C; Bartunek Petr; Sachs Martin; Birchmeier Walter; Zenke Martin
The impact of c-met/scatter factor receptor on dendritic cell migration.
European journal of immunology 2002;32(7):1832-8.
2002: Wong Melissa H; Huelsken Joerg; Birchmeier Walter; Gordon Jeffrey I
Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling.
The Journal of biological chemistry 2002;277(18):15843-50.
2002: Fujita Yasuyuki; Krause Gerd; Scheffner Martin; Zechner Dietmar; Leddy Hugo E Molina; Behrens Jürgen; Sommer Thomas; Birchmeier Walter
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex.
Nature cell biology 2002;4(3):222-31.
2002: Lustig Barbara; Jerchow Boris; Sachs Martin; Weiler Sigrid; Pietsch Torsten; Karsten Uwe; van de Wetering Marc; Clevers Hans; Schlag Peter M; Birchmeier Walter; Behrens Jürgen
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.
Molecular and cellular biology 2002;22(4):1184-93.
2002: Niemann Catherin; Owens David M; Hülsken Jörg; Birchmeier Walter; Watt Fiona M
Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours.
Development (Cambridge, England) 2002;129(1):95-109.
2001: Schmidt-Ullrich R; Aebischer T; Hülsken J; Birchmeier W; Klemm U; Scheidereit C
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices.
Development (Cambridge, England) 2001;128(19):3843-53.
2001: Huelsken J; Birchmeier W
New aspects of Wnt signaling pathways in higher vertebrates.
Current opinion in genetics & development 2001;11(5):547-53.
2001: Grimm J; Sachs M; Britsch S; Di Cesare S; Schwarz-Romond T; Alitalo K; Birchmeier W
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.
The Journal of cell biology 2001;154(2):345-54.
2001: Huelsken J; Vogel R; Erdmann B; Cotsarelis G; Birchmeier W
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.
Cell 2001;105(4):533-45.
2001: Lewitzky M; Kardinal C; Gehring N H; Schmidt E K; Konkol B; Eulitz M; Birchmeier W; Schaeper U; Feller S M
The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.
Oncogene 2001;20(9):1052-62.
2000: Sachs M; Brohmann H; Zechner D; Müller T; Hülsken J; Walther I; Schaeper U; Birchmeier C; Birchmeier W
Essential role of Gab1 for signaling by the c-Met receptor in vivo.
The Journal of cell biology 2000;150(6):1375-84.
2000: von Kries J P; Winbeck G; Asbrand C; Schwarz-Romond T; Sochnikova N; Dell'Oro A; Behrens J; Birchmeier W
Hot spots in beta-catenin for interactions with LEF-1, conductin and APC.
Nature structural biology 2000;7(9):800-7.
2000: Schaeper U; Gehring N H; Fuchs K P; Sachs M; Kempkes B; Birchmeier W
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.
The Journal of cell biology 2000;149(7):1419-32.
2000: Sakkab D; Lewitzky M; Posern G; Schaeper U; Sachs M; Birchmeier W; Feller S M
Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL.
The Journal of biological chemistry 2000;275(15):10772-8.
2000: Huelsken J; Vogel R; Brinkmann V; Erdmann B; Birchmeier C; Birchmeier W
Requirement for beta-catenin in anterior-posterior axis formation in mice.
The Journal of cell biology 2000;148(3):567-78.
2000: Niemann C; Brinkmann V; Birchmeier W
Hepatocyte growth factor and neuregulin in mammary gland cell morphogenesis.
Advances in experimental medicine and biology 2000;480():9-18.
1999: Isac C M; Ruiz P; Pfitzmaier B; Haase H; Birchmeier W; Morano I
Plakoglobin is essential for myocardial compliance but dispensable for myofibril insertion into adherens junctions.
Journal of cellular biochemistry 1999;72(1):8-15.
1998: Niemann C; Brinkmann V; Spitzer E; Hartmann G; Sachs M; Naundorf H; Birchmeier W
Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis.
The Journal of cell biology 1998;143(2):533-45.
1998: Behrens J; Jerchow B A; Würtele M; Grimm J; Asbrand C; Wirtz R; Kühl M; Wedlich D; Birchmeier W
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Science (New York, N.Y.) 1998;280(5363):596-9.
1998: Meiners S; Brinkmann V; Naundorf H; Birchmeier W
Role of morphogenetic factors in metastasis of mammary carcinoma cells.
Oncogene 1998;16(1):9-20.
1998: Hartmann G; Prospero T; Brinkmann V; Ozcelik C; Winter G; Hepple J; Batley S; Bladt F; Sachs M; Birchmeier C; Birchmeier W; Gherardi E;
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo.
Current biology : CB 1998;8(3):125-34.
1997: Zschiesche W; Schönborn I; Behrens J; Herrenknecht K; Hartveit F; Lilleng P; Birchmeier W
Expression of E-cadherin and catenins in invasive mammary carcinomas.
Anticancer research 1997;17(1B):561-7.
1997: Birchmeier W; Brinkmann V; Niemann C; Meiners S; DiCesare S; Naundorf H; Sachs M
Role of HGF/SF and c-Met in morphogenesis and metastasis of epithelial cells.
Ciba Foundation symposium 1997;212():230-40; discussion 240-6.
1996: Weidner K M; Di Cesare S; Sachs M; Brinkmann V; Behrens J; Birchmeier W
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
Nature 1996;384(6605):173-6.
1996: Ruiz P; Brinkmann V; Ledermann B; Behrend M; Grund C; Thalhammer C; Vogel F; Birchmeier C; Günthert U; Franke W W; Birchmeier W
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.
The Journal of cell biology 1996;135(1):215-25.
1996: Behrens J; von Kries J P; Kühl M; Bruhn L; Wedlich D; Grosschedl R; Birchmeier W
Functional interaction of beta-catenin with the transcription factor LEF-1.
Nature 1996;382(6592):638-42.
1996: Sachs M; Weidner K M; Brinkmann V; Walther I; Obermeier A; Ullrich A; Birchmeier W
Motogenic and morphogenic activity of epithelial receptor tyrosine kinases.
The Journal of cell biology 1996;133(5):1095-1107.
1996: Hennig G; Löwrick O; Birchmeier W; Behrens J
Mechanisms identified in the transcriptional control of epithelial gene expression.
The Journal of biological chemistry 1996;271(1):595-602.
1996: Birchmeier C; Birchmeier W; Brand-Saberi B
Epithelial-mesenchymal transitions in cancer progression.
Acta anatomica 1996;156(3):217-26.
1996: Birchmeier W; Behrens J; Weidner K M; Hülsken J; Birchmeier C
Epithelial differentiation and the control of metastasis in carcinomas.
Current topics in microbiology and immunology 1996;213 ( Pt 2)():117-35.
1995: Brinkmann V; Foroutan H; Sachs M; Weidner K M; Birchmeier W
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells.
The Journal of cell biology 1995;131(6 Pt 1):1573-86.
1995: Yang Y; Spitzer E; Meyer D; Sachs M; Niemann C; Hartmann G; Weidner K M; Birchmeier C; Birchmeier W
Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland.
The Journal of cell biology 1995;131(1):215-26.
1995: Hennig G; Behrens J; Truss M; Frisch S; Reichmann E; Birchmeier W
Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo.
Oncogene 1995;11(3):475-84.
1995: Weidner K M; Sachs M; Riethmacher D; Birchmeier W
Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2597-601.
1995: Birchmeier W
E-cadherin as a tumor (invasion) suppressor gene.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(2):97-9.
1995: Plaschke-Schlütter A; Behrens J; Gherardi E; Birchmeier W
Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cells.
The Journal of biological chemistry 1995;270(2):830-6.
1995: Birchmeier W; Hülsken J; Behrens J
E-cadherin as an invasion suppressor.
Ciba Foundation symposium 1995;189():124-36; discussion 136-41, 174-6.
1995: Birchmeier W; Hülsken J; Behrens J
Adherens junction proteins in tumour progression.
Cancer surveys 1995;24():129-40.
1994: Hülsken J; Birchmeier W; Behrens J
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.
The Journal of cell biology 1994;127(6 Pt 2):2061-9.
1994: Hülsken J; Behrens J; Birchmeier W
Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection.
Current opinion in cell biology 1994;6(5):711-6.
1994: Hartmann G; Weidner K M; Schwarz H; Birchmeier W
The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of Ras.
The Journal of biological chemistry 1994;269(35):21936-9.
1994: Kraus C; Liehr T; Hülsken J; Behrens J; Birchmeier W; Grzeschik K H; Ballhausen W G
Localization of the human beta-catenin gene (CTNNB1) to 3p21: a region implicated in tumor development.
Genomics 1994;23(1):272-4.
1994: Birchmeier W; Birchmeier C
Mesenchymal-epithelial transitions.
BioEssays : news and reviews in molecular, cellular and developmental biology 1994;16(5):305-7.
1994: Birchmeier W
Molecular aspects of the loss of cell adhesion and gain of invasiveness in carcinomas.
Princess Takamatsu symposia 1994;24():214-32.
1993: Birchmeier W; Weidner K M; Hülsken J; Behrens J
Molecular mechanisms leading to cell junction (cadherin) deficiency in invasive carcinomas.
Seminars in cancer biology 1993;4(4):231-9.
1993: Weidner K M; Hartmann G; Sachs M; Birchmeier W
Properties and functions of scatter factor/hepatocyte growth factor and its receptor c-Met.
American journal of respiratory cell and molecular biology 1993;8(3):229-37.
1993: Weidner K M; Hartmann G; Naldini L; Comoglio P M; Sachs M; Fonatsch C; Rieder H; Birchmeier W
Molecular characteristics of HGF-SF and its role in cell motility and invasion.
EXS 1993;65():311-28.
1993: Birchmeier W; Weidner K M; Behrens J
Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells.
Journal of cell science. Supplement 1993;17():159-64.
1992: Naldini L; Tamagnone L; Vigna E; Sachs M; Hartmann G; Birchmeier W; Daikuhara Y; Tsubouchi H; Blasi F; Comoglio P M
Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.
The EMBO journal 1992;11(13):4825-33.
1992: Hartmann G; Naldini L; Weidner K M; Sachs M; Vigna E; Comoglio P M; Birchmeier W
A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11574-8.
1992: Behrens J; Frixen U; Schipper J; Weidner M; Birchmeier W
Cell adhesion in invasion and metastasis.
Seminars in cell biology 1992;3(3):169-78.
1991: Schipper J H; Frixen U H; Behrens J; Unger A; Jahnke K; Birchmeier W
E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis.
Cancer research 1991;51(23 Pt 1):6328-37.
1991: Behrens J; Löwrick O; Klein-Hitpass L; Birchmeier W
The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11495-9.
1991: Birchmeier W; Behrens J; Weidner K M; Frixen U H; Schipper J
Dominant and recessive genes involved in tumor cell invasion.
Current opinion in cell biology 1991;3(5):832-40.
1991: Frixen U H; Behrens J; Sachs M; Eberle G; Voss B; Warda A; Löchner D; Birchmeier W
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.
The Journal of cell biology 1991;113(1):173-85.
1991: Behrens J; Weidner K M; Frixen U H; Schipper J H; Sachs M; Arakaki N; Daikuhara Y; Birchmeier W
The role of E-cadherin and scatter factor in tumor invasion and cell motility.
EXS 1991;59():109-26.
1990: Weidner K M; Behrens J; Vandekerckhove J; Birchmeier W
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells.
The Journal of cell biology 1990;111(5 Pt 1):2097-108.

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Walter Birchmeier

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