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Walter Birchmeier

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Jane D Holland; Alexandra Klaus; Alistair N Garratt; Walter Birchmeier
Wnt signaling in stem and cancer stem cells.
Regina Willecke; Frank Costantini; Katja Grossmann; Julian Heuberger; Odyssé Michos; Kai Schmidt-Ott; Katharina Walentin; Walter Birchmeier
The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney.
Felix H Brembeck; Yiyang Dai; Johannes Fritzmann; Tamara Grigoryan; Maria Wiese; Nathalie Zatula; Walter Birchmeier
BCL9-2 promotes early stages of intestinal tumor progression.

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All Publications

2013: Jane D Holland; Alexandra Klaus; Alistair N Garratt; Walter Birchmeier
Wnt signaling in stem and cancer stem cells.
Current opinion in cell biology 2013;25(2):254-64.
2011: Regina Willecke; Frank Costantini; Katja Grossmann; Julian Heuberger; Odyssé Michos; Kai Schmidt-Ott; Katharina Walentin; Walter Birchmeier
The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney.
Developmental biology 2011;360(2):310-7.
2011: Felix H Brembeck; Yiyang Dai; Johannes Fritzmann; Tamara Grigoryan; Maria Wiese; Nathalie Zatula; Walter Birchmeier
BCL9-2 promotes early stages of intestinal tumor progression.
Gastroenterology 2011;141(4):1359-70, 1370.e1-3.
2010: Peter Wend; Jane D Holland; Ulrike Ziebold; Walter Birchmeier
Wnt signaling in stem and cancer stem cells.
Seminars in cell & developmental biology 2010;21(8):855-63.
2010: Julian Heuberger; Walter Birchmeier
Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling.
Cold Spring Harbor perspectives in biology 2010;2(2):a002915.
2010: Karsten Jürchott; Ralf-Jürgen Kuban; Till Krech; Nils Blüthgen; Ulrike Stein; Wolfgang Walther; Christian Friese; Szymon M Kiełbasa; Ute Ungethüm; Per Lund; Thomas Knösel; Wolfgang Kemmner; Markus Morkel; Johannes Fritzmann; Peter M Schlag; Walter Birchmeier; Tammo Krueger; Silke Sperling; Christine Sers; hans-dieter royer; Hanspeter Herzel; Reinhold Schäfer
Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
PLoS genetics 2010;6(12):e1001231.
2009: Yuhang Zhang; Philip Tomann; Thomas Andl; Natalie M Gallant; Joerg Huelsken; Boris Jerchow; Walter Birchmeier; Ralf Paus; Stefano Piccolo; Marja L Mikkola; Edward Morrisey; Paul A Overbeek; Claus Scheidereit; Sarah E Millar; Ruth Schmidt-Ullrich
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction.
Developmental cell 2009;17(1):49-61.
2009: Johannes Fritzmann; Markus Morkel; Daniel Besser; Jan Budczies; Frauke Kosel; Felix H Brembeck; Ulrike Stein; Iduna Fichtner; Peter M Schlag; Walter Birchmeier
A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.
Gastroenterology 2009;137(1):165-75.
2009: Alexandra Klaus; Walter Birchmeier
Developmental signaling in myocardial progenitor cells: a comprehensive view of Bmp- and Wnt/beta-catenin signaling.
Pediatric cardiology 2009;30(5):609-16.
2009: Ulrike Stein; Wolfgang Walther; Franziska Arlt; Holger Schwabe; Janice Smith; Iduna Fichtner; Walter Birchmeier; Peter M Schlag
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
Nature medicine 2009;15(1):59-67.
2008: Klaus Hellmuth; Stefanie Grosskopf; Ching Tung Lum; Martin Würtele; Nadine Röder; Jens Peter von Kries; Marta Rosario; Jörg Rademann; Walter Birchmeier
Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(20):7275-80.
2008: Alexandra Klaus; Walter Birchmeier
Wnt signalling and its impact on development and cancer.
Nature reviews. Cancer 2008;8(5):387-98.
2008: Ilaria Malanchi; Hector Peinado; Deepika Kassen; Thomas Hussenet; Daniel Metzger; Pierre Chambon; Marcel Huber; Daniel Hohl; Amparo Cano; Walter Birchmeier; Joerg Huelsken
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.
Nature 2008;452(7187):650-3.
2008: Grégoire Jeannet; Marina Scheller; Léonardo Scarpellino; Stéphane Duboux; Noemie Gardiol; Jonathan Back; Fabien Kuttler; Ilaria Malanchi; Walter Birchmeier; Achim Leutz; Joerg Huelsken; Werner Held
Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.
Blood 2008;111(1):142-9.
2007: Ute Schaeper; Regina Vogel; Jolanta Chmielowiec; Joerg Huelsken; Marta Rosario; Walter Birchmeier
Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(39):15376-81.
2007: Marta Rosário; Renate Franke; Christien Bednarski; Walter Birchmeier
The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42.
The Journal of cell biology 2007;178(3):503-16.
2007: Anthony Baurand; Laura Zelarayan; Russell Betney; Christina Gehrke; Sandra Dunger; Claudia Noack; Andreas Busjahn; Joerg Huelsken; Makoto M Taketo; Walter Birchmeier; Rainer Dietz; Martin W Bergmann
Beta-catenin downregulation is required for adaptive cardiac remodeling.
Circulation research 2007;100(9):1353-62.
2007: Catherine Rose Hosking; Fausto Ulloa; Catherine Hogan; Emma C Ferber; Angélica Figueroa; Kris Gevaert; Walter Birchmeier; James Briscoe; Yasuyuki Fujita
The transcriptional repressor Glis2 is a novel binding partner for p120 catenin.
Molecular biology of the cell 2007;18(5):1918-27.
2007: Jolanta Chmielowiec; Malgorzata Borowiak; Markus Morkel; Theresia E B Stradal; Barbara Munz; Sabine Werner; Jürgen Wehland; Carmen Birchmeier; Walter Birchmeier
c-Met is essential for wound healing in the skin.
The Journal of cell biology 2007;177(1):151-62.
2007: Marisa M Faraldo; Jérôme Teulière; Marie-Ange Deugnier; Walter Birchmeier; Joerg Huelsken; Jean Paul Thiery; Amparo Cano; Marina A Glukhova
beta-Catenin regulates P-cadherin expression in mammary basal epithelial cells.
FEBS letters 2007;581(5):831-6.
2007: Dietmar Zechner; Thomas Müller; Hagen Wende; Ingrid Walther; Makoto M Taketo; E Bryan Crenshaw; Mathias Treier; Walter Birchmeier; Carmen Birchmeier
Bmp and Wnt/beta-catenin signals control expression of the transcription factor Olig3 and the specification of spinal cord neurons.
Developmental biology 2007;303(1):181-90.
2006: Heinz Moeller; Andreas Jenny; Hans-Joerg Schaeffer; Thomas Schwarz-Romond; Marek Mlodzik; Matthias Hammerschmidt; Walter Birchmeier
Diversin regulates heart formation and gastrulation movements in development.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(43):15900-5.
2006: Marina Scheller; Joerg Huelsken; Frank Rosenbauer; Makoto M Taketo; Walter Birchmeier; Daniel G Tenen; Achim Leutz
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
Nature immunology 2006;7(10):1037-47.
2006: Michel Hadjihannas; Martina Brückner; Boris Jerchow; Walter Birchmeier; Wolfgang Dietmaier; Jürgen Behrens
Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(28):10747-52.
2006: Calum A MacRae; Walter Birchmeier; Ludwig Thierfelder
Arrhythmogenic right ventricular cardiomyopathy: moving toward mechanism.
The Journal of clinical investigation 2006;116(7):1825-8.
2006: Felix H Brembeck; Marta Rosário; Walter Birchmeier
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin.
Current opinion in genetics & development 2006;16(1):51-9.
2005: Ulrich Stelzl; Uwe Worm; Maciej Lalowski; Christian Haenig; Felix H Brembeck; Heike Goehler; Martin Stroedicke; Martina Zenkner; Anke Schoenherr; Susanne Koeppen; Jan Timm; Sascha Mintzlaff; Claudia Abraham; Nicole Bock; Silvia Kietzmann; Astrid Goedde; Engin Toksöz; Anja Droege; Sylvia Krobitsch; Bernhard Korn; Walter Birchmeier; Hans Lehrach; Erich E Wanker
A human protein-protein interaction network: a resource for annotating the proteome.
Cell 2005;122(6):957-68.
2005: Weiguo Shu; Susan H Guttentag; Zhishan Wang; Thomas Andl; Philip L Ballard; Min Min Lu; Stefano Piccolo; Walter Birchmeier; Jeffrey A Whitsett; Sarah E Millar; Edward Morrisey
Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung.
Developmental biology 2005;283(1):226-39.
2005: Walter Birchmeier
Cell adhesion and signal transduction in cancer. Conference on cadherins, catenins and cancer.
EMBO reports 2005;6(5):413-7.
2005: Hsiao-Man Ivy Yu; Boris Jerchow; Tzong-Jen Sheu; Bo Liu; Frank Costantini; J Edward Puzas; Walter Birchmeier; Wei Hsu
The role of Axin2 in calvarial morphogenesis and craniosynostosis.
Development (Cambridge, England) 2005;132(8):1995-2005.
2004: Gunnar Schütz; Marta Rosário; Jan Grimm; Tobias M Boeckers; Eckart D Gundelfinger; Walter Birchmeier
The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells.
The Journal of cell biology 2004;167(5):945-52.
2004: Brenda Gerull; Arnd Heuser; Thomas Wichter; Matthias Paul; Craig T Basson; Deborah McDermott; Bruce B Lerman; Steve M Markowitz; Patrick T Ellinor; Calum A MacRae; Stefan Peters; Katja S Grossmann; Jörg Drenckhahn; Beate Michely; Sabine Sasse-Klaassen; Walter Birchmeier; Rainer Dietz; Günter Breithardt; Eric Schulze-Bahr; Ludwig Thierfelder
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy.
Nature genetics 2004;36(11):1162-4.
2004: Katja S Grossmann; Christine Grund; Joerg Huelsken; Martin Behrend; Bettina Erdmann; Werner W Franke; Walter Birchmeier
Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.
The Journal of cell biology 2004;167(1):149-60.
2004: Jérôme Teulière; Marisa M Faraldo; Michael Shtutman; Walter Birchmeier; Joerg Huelsken; Jean Paul Thiery; Marina A Glukhova
beta-catenin-dependent and -independent effects of DeltaN-plakoglobin on epidermal growth and differentiation.
Molecular and cellular biology 2004;24(19):8649-61.
2004: Felix H Brembeck; Thomas Schwarz-Romond; Jeroen Bakkers; Sabine Wilhelm; Matthias Hammerschmidt; Walter Birchmeier
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.
Genes & development 2004;18(18):2225-30.
2004: Catherine Hogan; Norberto Serpente; Patricia Cogram; Catherine Rose Hosking; Carl Uli Bialucha; Stephan Michael Feller; Vania M M Braga; Walter Birchmeier; Yasuyuki Fujita
Rap1 regulates the formation of E-cadherin-based cell-cell contacts.
Molecular and cellular biology 2004;24(15):6690-700.
2004: Marta Rosário; Walter Birchmeier
Making tubes: step by step.
Developmental cell 2004;7(1):3-5.
2004: Betty Lamothe; Masashi Yamada; Ute Schaeper; Walter Birchmeier; Irit Lax; Joseph Schlessinger
The docking protein Gab1 is an essential component of an indirect mechanism for fibroblast growth factor stimulation of the phosphatidylinositol 3-kinase/Akt antiapoptotic pathway.
Molecular and cellular biology 2004;24(13):5657-66.
2003: Carmen Birchmeier; Walter Birchmeier; Ermanno Gherardi; George Vande Woude
Met, metastasis, motility and more.
Nature reviews. Molecular cell biology 2003;4(12):915-25.
2003: Markus Morkel; Joerg Huelsken; Maki Wakamiya; Jixiang Ding; Marc van de Wetering; Hans Clevers; Makoto M Taketo; Richard R Behringer; Michael M Shen; Walter Birchmeier
Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation.
Development (Cambridge, England) 2003;130(25):6283-94.
2003: Youyuan Xu; Daliya Banerjee; Joerg Huelsken; Walter Birchmeier; Jyoti Misra Sen
Deletion of beta-catenin impairs T cell development.
Nature immunology 2003;4(12):1177-82.
2003: shernaz bamji; Kazuhiro Shimazu; Nikole Kimes; Joerg Huelsken; Walter Birchmeier; Bai Lu; Louis F Reichardt
Role of beta-catenin in synaptic vesicle localization and presynaptic assembly.
Neuron 2003;40(4):719-31.
2003: Michael L Mucenski; Susan E Wert; Jennifer M Nation; David E Loudy; Joerg Huelsken; Walter Birchmeier; Edward Morrisey; Jeffrey A Whitsett
beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis.
The Journal of biological chemistry 2003;278(41):40231-8.
2003: Natalia Soshnikova; Dietmar Zechner; Joerg Huelsken; Yuji Mishina; Richard R Behringer; Makoto M Taketo; E Bryan Crenshaw; Walter Birchmeier
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb.
Genes & development 2003;17(16):1963-8.
2003: Dietmar Zechner; Yasuyuki Fujita; Jörg Hülsken; Thomas Müller; Ingrid Walther; Makoto M Taketo; E Bryan Crenshaw; Walter Birchmeier; Carmen Birchmeier
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system.
Developmental biology 2003;258(2):406-18.
2003: Marta Rosário; Walter Birchmeier
How to make tubes: signaling by the Met receptor tyrosine kinase.
Trends in cell biology 2003;13(6):328-35.
2002: Thomas Schwarz-Romond; Christian Asbrand; Jeroen Bakkers; Michael Kühl; Hans-Joerg Schaeffer; Joerg Huelsken; Jürgen Behrens; Matthias Hammerschmidt; Walter Birchmeier
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling.
Genes & development 2002;16(16):2073-84.
2002: Steffen M Kurz; Sandra S Diebold; Thomas Hieronymus; Tatjana C Gust; Petr Bartunek; Martin Sachs; Walter Birchmeier; Martin Zenke
The impact of c-met/scatter factor receptor on dendritic cell migration.
European journal of immunology 2002;32(7):1832-8.
2002: Melissa H Wong; Joerg Huelsken; Walter Birchmeier; Jeffrey I Gordon
Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling.
The Journal of biological chemistry 2002;277(18):15843-50.
2002: Yasuyuki Fujita; Gerd Krause; Martin Scheffner; Dietmar Zechner; Hugo E Molina Leddy; Jürgen Behrens; Thomas Sommer; Walter Birchmeier
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex.
Nature cell biology 2002;4(3):222-31.
2002: Barbara Lustig; Boris Jerchow; Martin Sachs; Sigrid Weiler; Torsten Pietsch; Uwe Karsten; Marc van de Wetering; Hans Clevers; Peter M Schlag; Walter Birchmeier; Jürgen Behrens
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.
Molecular and cellular biology 2002;22(4):1184-93.
2002: Catherin Niemann; David M Owens; Jörg Hülsken; Walter Birchmeier; Fiona M Watt
Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours.
Development (Cambridge, England) 2002;129(1):95-109.
2001: R Schmidt-Ullrich; T Aebischer; Jörg Hülsken; Walter Birchmeier; U Klemm; Claus Scheidereit
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices.
Development (Cambridge, England) 2001;128(19):3843-53.
2001: Joerg Huelsken; Walter Birchmeier
New aspects of Wnt signaling pathways in higher vertebrates.
Current opinion in genetics & development 2001;11(5):547-53.
2001: J Grimm; M Sachs; S Britsch; S Di Cesare; Thomas Schwarz-Romond; K Alitalo; Walter Birchmeier
Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.
The Journal of cell biology 2001;154(2):345-54.
2001: Joerg Huelsken; Regina Vogel; Bettina Erdmann; George Cotsarelis; Walter Birchmeier
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.
Cell 2001;105(4):533-45.
2001: Marc Lewitzky; Christian Kardinal; N H Gehring; Enrico K Schmidt; B Konkol; M Eulitz; Walter Birchmeier; Ute Schaeper; Stephan M Feller
The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.
Oncogene 2001;20(9):1052-62.
2000: Martin Sachs; Henning Brohmann; Dietmar Zechner; Thomas Müller; Jörg Hülsken; Ingrid Walther; Ute Schaeper; Carmen Birchmeier; Walter Birchmeier
Essential role of Gab1 for signaling by the c-Met receptor in vivo.
The Journal of cell biology 2000;150(6):1375-84.
2000: J P von Kries; G Winbeck; Christian Asbrand; Thomas Schwarz-Romond; N Sochnikova; A Dell'Oro; Jürgen Behrens; Walter Birchmeier
Hot spots in beta-catenin for interactions with LEF-1, conductin and APC.
Nature structural biology 2000;7(9):800-7.
2000: Ute Schaeper; N H Gehring; KP Fuchs; Martin Sachs; Bettina Kempkes; Walter Birchmeier
Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.
The Journal of cell biology 2000;149(7):1419-32.
2000: D Sakkab; Marc Lewitzky; Guido Posern; Ute Schaeper; Martin Sachs; Walter Birchmeier; Stephan M Feller
Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL.
The Journal of biological chemistry 2000;275(15):10772-8.
2000: Joerg Huelsken; Regina Vogel; Volker Brinkmann; Bettina Erdmann; Carmen Birchmeier; Walter Birchmeier
Requirement for beta-catenin in anterior-posterior axis formation in mice.
The Journal of cell biology 2000;148(3):567-78.
2000: C Niemann; Volker Brinkmann; Walter Birchmeier
Hepatocyte growth factor and neuregulin in mammary gland cell morphogenesis.
Advances in experimental medicine and biology 2000;480():9-18.
1999: C M Isac; P Ruiz; B Pfitzmaier; Hannelore Haase; Walter Birchmeier; Ingo Morano
Plakoglobin is essential for myocardial compliance but dispensable for myofibril insertion into adherens junctions.
Journal of cellular biochemistry 1999;72(1):8-15.
1998: C Niemann; Volker Brinkmann; E Spitzer; Guido Hartmann; Martin Sachs; H Naundorf; Walter Birchmeier
Reconstitution of mammary gland development in vitro: requirement of c-met and c-erbB2 signaling for branching and alveolar morphogenesis.
The Journal of cell biology 1998;143(2):533-45.
1998: Jürgen Behrens; Boris Jerchow; M Würtele; J Grimm; Christian Asbrand; R Wirtz; Michael Kühl; Doris Wedlich; Walter Birchmeier
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
Science (New York, N.Y.) 1998;280(5363):596-9.
1998: P Ruiz; Walter Birchmeier
The plakoglobin knock-out mouse: a paradigm for the molecular analysis of cardiac cell junction formation.
Trends in cardiovascular medicine 1998;8(3):97-101.
1998: Guido Hartmann; TD Prospero; Volker Brinkmann; Cemil Ozcelik; G Winter; JP Hepple; S Batley; F Bladt; Martin Sachs; Carmen Birchmeier; Walter Birchmeier; Ermanno Gherardi; O Ozcelik
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo.
Current biology : CB 1998;8(3):125-34.
1998: S Meiners; Volker Brinkmann; H Naundorf; Walter Birchmeier
Role of morphogenetic factors in metastasis of mammary carcinoma cells.
Oncogene 1998;16(1):9-20.
1997: Walter Birchmeier; Volker Brinkmann; C Niemann; S Meiners; S DiCesare; H Naundorf; Martin Sachs
Role of HGF/SF and c-Met in morphogenesis and metastasis of epithelial cells.
Ciba Foundation symposium 1997;212():230-40; discussion 240-6.
1997: W Zschiesche; I Schönborn; Jürgen Behrens; K Herrenknecht; F Hartveit; Peer Lilleng; Walter Birchmeier
Expression of E-cadherin and catenins in invasive mammary carcinomas.
Anticancer research 1997;17(1B):561-7.
1996: K M Weidner; S Di Cesare; Martin Sachs; Volker Brinkmann; Jürgen Behrens; Walter Birchmeier
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
Nature 1996;384(6605):173-6.
1996: P Ruiz; Volker Brinkmann; B Ledermann; M Behrend; C Grund; C Thalhammer; F Vogel; Carmen Birchmeier; U Günthert; W W Franke; Walter Birchmeier
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.
The Journal of cell biology 1996;135(1):215-25.
1996: Jürgen Behrens; J P von Kries; Michael Kühl; L Bruhn; Doris Wedlich; Rudolf Grosschedl; Walter Birchmeier
Functional interaction of beta-catenin with the transcription factor LEF-1.
Nature 1996;382(6592):638-42.
1996: Martin Sachs; K M Weidner; Volker Brinkmann; I Walther; A Obermeier; A Ullrich; Walter Birchmeier
Motogenic and morphogenic activity of epithelial receptor tyrosine kinases.
The Journal of cell biology 1996;133(5):1095-1107.
1996: G Hennig; O Löwrick; Walter Birchmeier; Jürgen Behrens
Mechanisms identified in the transcriptional control of epithelial gene expression.
The Journal of biological chemistry 1996;271(1):595-602.
1996: Carmen Birchmeier; Walter Birchmeier; Beate Brand-Saberi
Epithelial-mesenchymal transitions in cancer progression.
Acta anatomica 1996;156(3):217-26.
1996: Walter Birchmeier; Jürgen Behrens; K M Weidner; J Hülsken; Carmen Birchmeier
Epithelial differentiation and the control of metastasis in carcinomas.
Current topics in microbiology and immunology 1996;213 ( Pt 2)():117-35.
1995: Volker Brinkmann; H Foroutan; Martin Sachs; K M Weidner; Walter Birchmeier
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells.
The Journal of cell biology 1995;131(6 Pt 1):1573-86.
1995: Y Yang; E Spitzer; D Meyer; Martin Sachs; C Niemann; Guido Hartmann; K M Weidner; Carmen Birchmeier; Walter Birchmeier
Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland.
The Journal of cell biology 1995;131(1):215-26.
1995: G Hennig; Jürgen Behrens; M Truss; S Frisch; E Reichmann; Walter Birchmeier
Progression of carcinoma cells is associated with alterations in chromatin structure and factor binding at the E-cadherin promoter in vivo.
Oncogene 1995;11(3):475-84.
1995: K M Weidner; Martin Sachs; Dieter Riethmacher; Walter Birchmeier
Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2597-601.
1995: Walter Birchmeier
E-cadherin as a tumor (invasion) suppressor gene.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(2):97-9.
1995: A Plaschke-Schlütter; Jürgen Behrens; E Gherardi; Walter Birchmeier
Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cells.
The Journal of biological chemistry 1995;270(2):830-6.
1995: Walter Birchmeier; J Hülsken; Jürgen Behrens
E-cadherin as an invasion suppressor.
Ciba Foundation symposium 1995;189():124-36; discussion 136-41, 174-6.
1995: Walter Birchmeier; J Hülsken; Jürgen Behrens
Adherens junction proteins in tumour progression.
Cancer surveys 1995;24():129-40.
1994: J Hülsken; Walter Birchmeier; Jürgen Behrens
E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.
The Journal of cell biology 1994;127(6 Pt 2):2061-9.
1994: J Hülsken; Jürgen Behrens; Walter Birchmeier
Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection.
Current opinion in cell biology 1994;6(5):711-6.
1994: Guido Hartmann; K M Weidner; H Schwarz; Walter Birchmeier
The motility signal of scatter factor/hepatocyte growth factor mediated through the receptor tyrosine kinase met requires intracellular action of Ras.
The Journal of biological chemistry 1994;269(35):21936-9.
1994: Cornelia Kraus; T Liehr; J Hülsken; Jürgen Behrens; Walter Birchmeier; K H Grzeschik; Wolfgang G Ballhausen
Localization of the human beta-catenin gene (CTNNB1) to 3p21: a region implicated in tumor development.
Genomics 1994;23(1):272-4.
1994: Walter Birchmeier; Carmen Birchmeier
Mesenchymal-epithelial transitions.
BioEssays : news and reviews in molecular, cellular and developmental biology 1994;16(5):305-7.
1994: Walter Birchmeier
Molecular aspects of the loss of cell adhesion and gain of invasiveness in carcinomas.
Princess Takamatsu symposia 1994;24():214-32.
1993: Walter Birchmeier; K M Weidner; J Hülsken; Jürgen Behrens
Molecular mechanisms leading to cell junction (cadherin) deficiency in invasive carcinomas.
Seminars in cancer biology 1993;4(4):231-9.
1993: K M Weidner; Guido Hartmann; Martin Sachs; Walter Birchmeier
Properties and functions of scatter factor/hepatocyte growth factor and its receptor c-Met.
American journal of respiratory cell and molecular biology 1993;8(3):229-37.
1993: K M Weidner; Guido Hartmann; L Naldini; paolo comoglio; Martin Sachs; C Fonatsch; H Rieder; Walter Birchmeier
Molecular characteristics of HGF-SF and its role in cell motility and invasion.
EXS 1993;65():311-28.
1993: Walter Birchmeier; K M Weidner; Jürgen Behrens
Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells.
Journal of cell science. Supplement 1993;17():159-64.
1992: L Naldini; Luca Tamagnone; Elisa Vigna; Martin Sachs; Guido Hartmann; Walter Birchmeier; Y Daikuhara; H Tsubouchi; F Blasi; paolo comoglio
Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.
The EMBO journal 1992;11(13):4825-33.
1992: Guido Hartmann; L Naldini; K M Weidner; Martin Sachs; Elisa Vigna; paolo comoglio; Walter Birchmeier
A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(23):11574-8.
1992: Jürgen Behrens; U Frixen; J Schipper; M Weidner; Walter Birchmeier
Cell adhesion in invasion and metastasis.
Seminars in cell biology 1992;3(3):169-78.
1991: Jürgen Behrens; O Löwrick; L Klein-Hitpass; Walter Birchmeier
The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11495-9.
1991: J H Schipper; U H Frixen; Jürgen Behrens; A Unger; K Jahnke; Walter Birchmeier
E-cadherin expression in squamous cell carcinomas of head and neck: inverse correlation with tumor dedifferentiation and lymph node metastasis.
Cancer research 1991;51(23 Pt 1):6328-37.
1991: Walter Birchmeier; Jürgen Behrens; K M Weidner; U H Frixen; J Schipper
Dominant and recessive genes involved in tumor cell invasion.
Current opinion in cell biology 1991;3(5):832-40.
1991: U H Frixen; Jürgen Behrens; Martin Sachs; G Eberle; B Voss; A Warda; D Löchner; Walter Birchmeier
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.
The Journal of cell biology 1991;113(1):173-85.
1991: Jürgen Behrens; K M Weidner; U H Frixen; J H Schipper; Martin Sachs; N Arakaki; Yasushi Daikuhara; Walter Birchmeier
The role of E-cadherin and scatter factor in tumor invasion and cell motility.
EXS 1991;59():109-26.
1990: K M Weidner; Jürgen Behrens; J Vandekerckhove; Walter Birchmeier
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells.
The Journal of cell biology 1990;111(5 Pt 1):2097-108.