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José-Alain Sahel

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Guillaume Euvrard; Olivier Genevois; Pascale Massin; Isabelle Rivals; José-Alain Sahel; Amélie Collet; Michel Paques
A semi-automated computer tool for the analysis of retinal vessel diameter dynamics.
Marie-Hélène Errera; Pablo Goldschmidt; Emmanuel Héron; Laurent Laroche; José-Alain Sahel; Mark Westcott; L Batellier; Sandrine Degorge; Christine Chaumeil
Findings in detection of Herpesviridae by polymerase chain reaction and intraocular antibody production in a case series of anterior uveitis.
Christina Zeitz; Aline Antonio; Claire Audier; Shomi S Bhattacharya; Béatrice Bocquet; Kinga Bujakowska; Hélène Dollfus; Christian P Hamel; Samuel G Jacobson; Susanne Kohl; Marie-Elise Lancelot; Odile Lecompte; Mélanie Letexier; Tien D Luu; Christelle Michiels; Marion Neuillé; Hoan Nguyen; Elise Orhan; Olivier Poch; José-Alain Sahel; Jean-Paul Saraiva; Sharon B Schwartz; Florian Sennlaub; Xavier Zanlonghi; Isabelle Audo
Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness.

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2013: Guillaume Euvrard; Olivier Genevois; Pascale Massin; Isabelle Rivals; José-Alain Sahel; Amélie Collet; Michel Paques
A semi-automated computer tool for the analysis of retinal vessel diameter dynamics.
Computers in biology and medicine 2013;43(5):513-23.
2013: Marie-Hélène Errera; Pablo Goldschmidt; Emmanuel Héron; Laurent Laroche; José-Alain Sahel; Mark Westcott; L Batellier; Sandrine Degorge; Christine Chaumeil
Findings in detection of Herpesviridae by polymerase chain reaction and intraocular antibody production in a case series of anterior uveitis.
Ocular immunology and inflammation 2013;21(1):46-53.
2013: Christina Zeitz; Aline Antonio; Claire Audier; Shomi S Bhattacharya; Béatrice Bocquet; Kinga Bujakowska; Hélène Dollfus; Christian P Hamel; Samuel G Jacobson; Susanne Kohl; Marie-Elise Lancelot; Odile Lecompte; Mélanie Letexier; Tien D Luu; Christelle Michiels; Marion Neuillé; Hoan Nguyen; Elise Orhan; Olivier Poch; José-Alain Sahel; Jean-Paul Saraiva; Sharon B Schwartz; Florian Sennlaub; Xavier Zanlonghi; Isabelle Audo
Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness.
American journal of human genetics 2013;92(1):67-75.
2013: Alexis Bemelmans; Mélissa Desrosiers; Sandra Duqué; Thibault Marais; Christel Rivière; José-Alain Sahel; Thomas Voit; Stéphanie Astord; Martine Barkats
A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina.
PloS one 2013;8(4):e61618.
2013: Jean-François Girmens; Serge Picaud; José-Alain Sahel
[Therapeutic innovation in AMD and other retinal diseases].
La Revue du praticien 2013;63(1):68-73.
2013: José-Alain Sahel
[Ophthalmology, between spectacular advances and gaps in managed care].
La Revue du praticien 2013;63(1):39-41.
2013: Serge-George Rosolen; José-Alain Sahel; Nathalie Neveux; Serge Picaud; Nicolas Froger
Evaluation of the taurine concentrations in dog plasma and aqueous humour: a pilot study.
Advances in experimental medicine and biology 2013;775():145-54.
2013: Nicolas Froger; david gaucher; Ivana Ivkovic; Firas Jammoul; Henri Lorach; Dorothée Pain; Lucia Cadetti; Julie Degardin; Elisabeth Dubus; Valérie Forster; José-Alain Sahel; Manuel Simonutti; Serge Picaud
Taurine is a crucial factor to preserve retinal ganglion cell survival.
Advances in experimental medicine and biology 2013;775():69-83.
2012: Christophe Lechauve; Michael C Marden; Pierre Rustin; José-Alain Sahel; Sébastien Augustin; Aïcha Bouaita; Chantal Célier; Hélène Cwerman-Thibault; Valérie Forster; Marisol Corral-Debrinski
Neuroglobin involvement in respiratory chain function and retinal ganglion cell integrity.
Biochimica et biophysica acta 2012;1823(12):2261-73.
2012: david gaucher; Pauline Gondouin; Zoé Husson; Pascale Massin; Izzie J Namer; José-Alain Sahel; Manuel Simonutti; Emilie Arnault; M A Benahmed; Julie Degardin; Diane Dherbécourt; Elisabeth Dubus; Karim Elbayed; Stéphane Fouquet; Nicolas Froger; Serge Picaud
Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells.
Amino acids 2012;43(5):1979-93.
2012: I Sahly; Cataldo Schietroma; Dominique Weil; José-Alain Sahel; Asadollah Aghaie; Amel Bahloul; Diane Carette; Eric Dufour; Inga Ebermann; Aziz El-Amraoui; Amrit Estivalet; Jean-Pierre Hardelin; Maria Iribarne; Andrea Lelli; Vincent Michel; Elise Pepermans; Isabelle Perfettini; Christine Petit
Localization of Usher 1 proteins to the photoreceptor calyceal processes, which are absent from mice.
The Journal of cell biology 2012;199(2):381-99.
2012: Marni J Falk; Zoe Fonseca-Kelly; Xiaowu Gai; Subhadra Jalali; Chitra Kannabiran; Qin Liu; Mackay Donna; Saddek Mohand-Said; Anthony T Moore; Eiko Nakamaru-Ogiso; Julian Ostrovsky; Lakshmi Palavalli; Juan C Perin; Emily Place; José-Alain Sahel; Rachna Shukla; Magdalena Staniszewska; Naushin Waseem; Andrew R Webster; Rui Xiao; Christina Zeitz; Qi Zhang; Isabelle Audo; Eliot L Berson; Shomi S Bhattacharya; Arundhati Dev Borman; Christina F Chakarova; Mark Consugar; Eric A Pierce
NMNAT1 mutations cause Leber congenital amaurosis.
Nature genetics 2012;44(9):1040-5.
2012: Georges Azar; Pierre-Loïc Cornut; José-Alain Sahel; Benjamin Wolff; Martine Mauget-Faÿsse
Spectral domain optical coherence tomography evolutive features in acute macular neuroretinopathy.
European journal of ophthalmology 2012;22(5):850-2.
2012: Céline Jaillard; Bernd Kinzel; Irene Lee-Rivera; Najate Aït-Ali; Jean Bennett; Emmanuelle Clérin; Thérèse Cronin; Pierre-Marie Lledo; Géraldine Millet-Puel; Aurélie Mouret; Marie-Laure Niepon; Olivier Poch; Wolfgang Raffelsberger; José-Alain Sahel; Tina Sedmak; Alain Trembleau; Uwe Wolfrum; Ying Yang; Thierry Léveillard
Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity.
Human molecular genetics 2012;21(10):2298-311.
2012: Mark S Humayun; Avinoam B Safran; José-Alain Sahel; Arturo Santos; Paulo E Stanga; Aries Arditi; Artur V Cideciyan; Lyndon da Cruz; Gislin Dagnelie; Lucian V Del Priore; Jessy D Dorn; Jacque L Duncan; Dean Eliott; Eugene Filley; Robert J Greenberg; Allen C Ho
Interim results from the international trial of Second Sight's visual prosthesis.
Ophthalmology 2012;119(4):779-88.
2012: Elise C Lelièvre; Laurence Mahieu; Jérome E Roger; José-Alain Sahel; Florian Sennlaub; Reiner A Veitia; Bérénice A Benayoun; Olivier Goureau; xavier guillonneau
A regulatory domain is required for Foxn4 activity during retinogenesis.
Journal of molecular neuroscience : MN 2012;46(2):315-23.
2012: Nicolas Froger; Ivana Ivkovic; Firas Jammoul; Thierry Léveillard; Henri Lorach; Joao Martins; Dorothée Pain; Alexis Bemelmans; Ryad Benosman; Lucia Cadetti; Laurent Chicaud; Julie Degardin; Elisabeth Dubus; Valérie Forster; Stéphane Fouquet; José-Alain Sahel; Manuel Simonutti; Serge Picaud
Taurine provides neuroprotection against retinal ganglion cell degeneration.
PloS one 2012;7(10):e42017.
2012: Benjamin Wolff; Alexandre Matet; José-Alain Sahel; Vivien Vasseur; Martine Mauget-Faÿsse
En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration.
Journal of ophthalmology 2012;2012():542417.
2012: Isabelle Audo; Shomi S Bhattacharya; Kinga M Bujakowska; Aurore Germain; Marie-Elise Lancelot; Mélanie Letexier; Thierry Léveillard; Christelle Michiels; Saddek Mohand-Saïd; José-Alain Sahel; Jean-Paul Saraiva; Aline Antonio; Christina Zeitz
Development and application of a next-generation-sequencing (NGS) approach to detect known and novel gene defects underlying retinal diseases.
Orphanet journal of rare diseases 2012;7():8.
2012: Aicha Bouaita; Sébastien Augustin; Paule Bénit; Hélène Cwerman-Thibault; Christophe Lechauve; Michel Paques; Pierre Rustin; José-Alain Sahel; Manuel Simonutti; Marisol Corral-Debrinski
Downregulation of apoptosis-inducing factor in Harlequin mice induces progressive and severe optic atrophy which is durably prevented by AAV2-AIF1 gene therapy.
Brain : a journal of neurology 2012;135(Pt 1):35-52.
2011: Marie-Hélène Errera; Pablo Goldschmidt; Emmanuel Héron; Laurent Laroche; José-Alain Sahel; Mark Westcott; L Batellier; Sandrine Degorge; Christine Chaumeil
Real-time polymerase chain reaction and intraocular antibody production for the diagnosis of viral versus toxoplasmic infectious posterior uveitis.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2011;249(12):1837-46.
2011: Anne Galy; Céline Diebold; Abrar Qurashi; José-Alain Sahel; H Bahar Sahin; Annette Schenck; Angela Giangrande
CYFIP dependent actin remodeling controls specific aspects of Drosophila eye morphogenesis.
Developmental biology 2011;359(1):37-46.
2011: E C Lelièvre; J M Matter; J E Roger; José-Alain Sahel; F Sennlaub; A Slembrouck; H Boije; V Brajeul; Olivier Goureau; Finn Hallböök; L Houille-Vernes; M Lek; xavier guillonneau
Ptf1a/Rbpj complex inhibits ganglion cell fate and drives the specification of all horizontal cell subtypes in the chick retina.
Developmental biology 2011;358(2):296-308.
2011: Benjamin Wolff; José-Alain Sahel; Maddalena Quaranta-El Maftouhi; Aranzazu Mateo-Montoya; Martine Mauget-Faÿsse
Outer retinal cysts in age-related macular degeneration.
Acta ophthalmologica 2011;89(6):e496-9.
2011: Feng Liang; Michel Paques; Pierre Olivier Barale; Khé Hoang Xuan; José-Alain Sahel
Subretinal lymphomatous infiltration in primary intraocular lymphoma revealed by optical coherence tomography.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2011;249(9):1425-7.
2011: José-Alain Sahel
Spotlight on childhood blindness.
The Journal of clinical investigation 2011;121(6):2145-9.
2011: Isabelle Audo; John Conrath; Mohamed El Sanharawi; Dominique Fompeydie; Kiyoko Gocho-Nakashima; Olivier Goureau; Annie Morin; José-Alain Sahel; Catherine Vignal-Clermont; Antoine Villa; Michel Paques
Foveal damage in habitual poppers users.
Archives of ophthalmology 2011;129(6):703-8.
2011: José-Alain Sahel
Quality versus quantity: assessing individual research performance.
Science translational medicine 2011;3(84):84cm13.
2011: Mathias Fradot; Volker Busskamp; Valérie Forster; Thérèse Cronin; Thierry Léveillard; Jean Bennett; José-Alain Sahel; Botond Roska; Serge Picaud
Gene therapy in ophthalmology: validation on cultured retinal cells and explants from postmortem human eyes.
Human gene therapy 2011;22(5):587-93.
2011: Céline Faure; Richard Macrez; Denis Vivien; José-Alain Sahel; Sébastien Bonnel
Interaction study between rtPA and bevacizumab.
The British journal of ophthalmology 2011;95(5):743-4.
2011: Isabelle Audo; Marie-Elise Lancelot; Saddek Mohand-Saïd; Aline Antonio; Aurore Germain; José-Alain Sahel; Shomi S Bhattacharya; Christina Zeitz
Novel C2orf71 mutations account for ∼1% of cases in a large French arRP cohort.
Human mutation 2011;32(4):E2091-103.
2011: Hélène Cwerman-Thibault; José-Alain Sahel; Marisol Corral-Debrinski
Mitochondrial medicine: to a new era of gene therapy for mitochondrial DNA mutations.
Journal of inherited metabolic disease 2011;34(2):327-44.
2011: Thomas Gaujoux; Enwar Borsali; Pablo Goldschmidt; Christine Chaumeil; Christophe Baudouin; Jean Philippe Nordmann; José-Alain Sahel; Laurent Laroche; Vincent M Borderie
Fungal keratitis in France.
Acta ophthalmologica 2011;89(2):e215-6.
2011: Sercan Deniz; Eric Wersinger; Yannick Schwab; Carole Mura; Ferenc Erdelyi; Gábor Szabó; Alvaro Rendon; José-Alain Sahel; Serge Picaud; Michel J Roux
Mammalian retinal horizontal cells are unconventional GABAergic neurons.
Journal of neurochemistry 2011;116(3):350-62.
2011: Emmanuelle Clérin; Saddek Mohand-Saïd; Olivier Poch; José-Alain Sahel; Nicolas Wicker; Thierry Léveillard
℮-conome: an automated tissue counting platform of cone photoreceptors for rodent models of retinitis pigmentosa.
BMC ophthalmology 2011;11():38.
2011: Eric Wersinger; José-Alain Sahel; Yannick Schwab; Abdoulaye Sene; Violaine Alunni; Romain Bénard; Agnès Bordais; Alvaro Rendon; Michel J Roux
Reevaluation of dystrophin localization in the mouse retina.
Investigative ophthalmology & visual science 2011;52(11):7901-8.
2011: Isabelle Audo; Shomi Bhattacharya; Kinga Bujakowska; Wassila Carpentier; Aurore Germain; Marie-Elise Lancelot; Christine Lonjou; Saddek Mohand-Saïd; José-Alain Sahel; Sophie Tronche; Aline Antonio; Christina Zeitz
A novel DFNB31 mutation associated with Usher type 2 syndrome showing variable degrees of auditory loss in a consanguineous Portuguese family.
Molecular vision 2011;17():1598-606.
2010: Serge G Rosolen; Barbara Lamory; Fabrice Harms; José-Alain Sahel; Serge Picaud; Jean-François LeGargasson
Cellular-resolution in vivo imaging of the feline retina using adaptive optics: preliminary results.
Veterinary ophthalmology 2010;13(6):369-76.
2010: Michel Paques; Manuel Simonutti; Sébastien Augustin; Olivier Goupille; Brahim El Mathari; José-Alain Sahel
In vivo observation of the locomotion of microglial cells in the retina.
Glia 2010;58(14):1663-8.
2010: Catherine Vignal-Clermont; Isabelle Audo; José-Alain Sahel; Michel Paques
Poppers-associated retinal toxicity.
The New England journal of medicine 2010;363(16):1583-5.
2010: Isabelle Audo; Anne Friedrich; Saddek Mohand-Saïd; Marie-Elise Lancelot; Aline Antonio; Veselina Moskova-Doumanova; Olivier Poch; Shomi Bhattacharya; José-Alain Sahel; Christina Zeitz
An unusual retinal phenotype associated with a novel mutation in RHO.
Archives of ophthalmology 2010;128(8):1036-45.
2010: Volker Busskamp; Jens Duebel; David Balya; Mathias Fradot; Tim Viney; Sandra Siegert; Anna C Groner; Erik Cabuy; Valérie Forster; Mathias Seeliger; Martin Biel; Peter Humphries; Michel Paques; Saddek Mohand-Said; Didier Trono; Karl Deisseroth; José-Alain Sahel; Serge Picaud; Botond Roska
Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa.
Science (New York, N.Y.) 2010;329(5990):413-7.
2010: Isabelle Audo; Gaël Manes; Saddek Mohand-Saïd; Anne Friedrich; Marie-Elise Lancelot; Aline Antonio; Veselina Moskova-Doumanova; Oliver Poch; Xavier Zanlonghi; Christian P Hamel; José-Alain Sahel; Shomi S Bhattacharya; Christina Zeitz
Spectrum of rhodopsin mutations in French autosomal dominant rod-cone dystrophy patients.
Investigative ophthalmology & visual science 2010;51(7):3687-700.
2010: T Cronin; W Raffelsberger; I Lee-Rivera; C Jaillard; M-L Niepon; B Kinzel; E Clérin; A Petrosian; Serge Picaud; Olivier Poch; José-Alain Sahel; Thierry Léveillard
The disruption of the rod-derived cone viability gene leads to photoreceptor dysfunction and susceptibility to oxidative stress.
Cell death and differentiation 2010;17(7):1199-210.
2010: Didier Pruneau; Pierre Bélichard; José-Alain Sahel; Jean-Philippe Combal
Targeting the kallikrein-kinin system as a new therapeutic approach to diabetic retinopathy.
Current opinion in investigational drugs (London, England : 2000) 2010;11(5):507-14.
2010: Isabelle Audo; José-Alain Sahel; Saddek Mohand-Saïd; Marie-Elise Lancelot; Aline Antonio; Veselina Moskova-Doumanova; Emeline F Nandrot; Jordan Doumanov; Isabel Barragan; Guillermo Antinolo; Shomi S Bhattacharya; Christina Zeitz
EYS is a major gene for rod-cone dystrophies in France.
Human mutation 2010;31(5):E1406-35.
2010: Thierry Léveillard; José-Alain Sahel
Rod-derived cone viability factor for treating blinding diseases: from clinic to redox signaling.
Science translational medicine 2010;2(26):26ps16.
2010: Firas Jammoul; Julie Dégardin; Dorothée Pain; Pauline Gondouin; Manuel Simonutti; Elisabeth Dubus; Romain Caplette; Stéphane Fouquet; Cheryl M Craft; José-Alain Sahel; Serge Picaud
Taurine deficiency damages photoreceptors and retinal ganglion cells in vigabatrin-treated neonatal rats.
Molecular and cellular neurosciences 2010;43(4):414-21.
2010: Isabelle Audo; José-Alain Sahel; Shomi Bhattacharya; Christina Zeitz
[TRPM1, a new gene implicated in congenital stationary night blindness].
Médecine sciences : M/S 2010;26(3):241-4.
2010: Aranzazu Mateo-Montoya; Dinu Stanescu; Benjamin Wolff; José-Alain Sahel; Sébastien Bonnel
Cytomegalovirus retinitis associated with Good's syndrome.
European journal of ophthalmology 2010;20(2):479-80.
2010: Alexandre Bourhis; Jean-Francois GIRMENS; Severin Boni; Florence Pecha; Catherine Favard; José-Alain Sahel; Michel Paques
Imaging of macroaneurysms occurring during retinal vein occlusion and diabetic retinopathy by indocyanine green angiography and high resolution optical coherence tomography.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2010;248(2):161-6.
2010: Sacha Reichman; Ravi Kiran Reddy Kalathur; Sophie Lambard; Najate Aït-Ali; Yanjiang Yang; Aurélie Lardenois; Raymond Ripp; Olivier Poch; Donald J Zack; José-Alain Sahel; Thierry Léveillard
The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina.
Human molecular genetics 2010;19(2):250-61.
2010: Ying Yang; Saddek Mohand-Said; Thierry Léveillard; Valérie Fontaine; Manuel Simonutti; José-Alain Sahel
Transplantation of photoreceptor and total neural retina preserves cone function in P23H rhodopsin transgenic rat.
PloS one 2010;5(10):e13469.
2010: Sophie Lambard; Sacha Reichman; CYNTHIA BERLINICKE; Marie-Laure Niepon; Olivier Goureau; José-Alain Sahel; Thierry Léveillard; Donald J Zack
Expression of rod-derived cone viability factor: dual role of CRX in regulating promoter activity and cell-type specificity.
PloS one 2010;5(10):e13075.
2010: Isabelle Audo; Kinga Bujakowska; Saddek Mohand-Saïd; Marie-Elise Lancelot; Veselina Moskova-Doumanova; Naushin H Waseem; Aline Antonio; José-Alain Sahel; Shomi S Bhattacharya; Christina Zeitz
Prevalence and novelty of PRPF31 mutations in French autosomal dominant rod-cone dystrophy patients and a review of published reports.
BMC medical genetics 2010;11():145.
2009: Christina Zeitz; Stephan Labs; Birgit Lorenz; Ursula Forster; Janne Uksti; Hester Y Kroes; Elfride De Baere; Bart P Leroy; Frans P M Cremers; Mariana Wittmer; Maria van Genderen; José-Alain Sahel; Isabelle Audo; Charlotte M Poloschek; Saddek Mohand-Saïd; Johannes C Fleischhauer; Ulrike Hüffmeier; Veselina Moskova-Doumanova; Alex V Levin; Christian P Hamel; Dorothee Leifert; Francis L Munier; Daniel F Schorderet; Eberhart Zrenner; Christoph Friedburg; Bernd Wissinger; Susanne Kohl; Wolfgang Berger
Genotyping microarray for CSNB-associated genes.
Investigative ophthalmology & visual science 2009;50(12):5919-26.
2009: Isabelle Audo; Susanne Kohl; Bart P Leroy; Francis L Munier; xavier guillonneau; Saddek Mohand-Saïd; Kinga Bujakowska; Emeline F Nandrot; Birgit Lorenz; Markus Preising; Ulrich Kellner; Agnes B Renner; Antje Bernd; Aline Antonio; Veselina Moskova-Doumanova; Marie-Elise Lancelot; Charlotte M Poloschek; Isabelle Drumare; Sabine Defoort-Dhellemmes; Bernd Wissinger; Thierry Léveillard; Christian P Hamel; Daniel F Schorderet; Elfride De Baere; Wolfgang Berger; Samuel G Jacobson; Eberhart Zrenner; José-Alain Sahel; Shomi S Bhattacharya; Christina Zeitz
TRPM1 is mutated in patients with autosomal-recessive complete congenital stationary night blindness.
American journal of human genetics 2009;85(5):720-9.
2009: Ying Yang; Saddek Mohand-Said; Aude Danan; Manuel Simonutti; Valérie Fontaine; Emmanuelle Clerin; Serge Picaud; Thierry Léveillard; José-Alain Sahel
Functional cone rescue by RdCVF protein in a dominant model of retinitis pigmentosa.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(5):787-95.
2009: Firas Jammoul; Qingping Wang; Rima Nabbout; Caroline Coriat; Agnès Duboc; Manuel Simonutti; Elisabeth Dubus; Cheryl M Craft; Wen Ye; Stephen D Collins; Olivier Dulac; Catherine Chiron; José-Alain Sahel; Serge Picaud
Taurine deficiency is a cause of vigabatrin-induced retinal phototoxicity.
Annals of neurology 2009;65(1):98-107.
2008: Jean-Laurent Guyomard; Serge G Rosolen; Michel Paques; Marie-Noelle Delyfer; Manuel Simonutti; Yann Tessier; José-Alain Sahel; Jean-François LeGargasson; Serge Picaud
A low-cost and simple imaging technique of the anterior and posterior segments: eye fundus, ciliary bodies, iridocorneal angle.
Investigative ophthalmology & visual science 2008;49(11):5168-74.
2008: Crystel Bonnet; Sébastien Augustin; Sami Ellouze; Paule Bénit; Aicha Bouaita; Pierre Rustin; José-Alain Sahel; Marisol Corral-Debrinski
The optimized allotopic expression of ND1 or ND4 genes restores respiratory chain complex I activity in fibroblasts harboring mutations in these genes.
Biochimica et biophysica acta 2008;1783(10):1707-17.
2008: Sami Ellouze; Sébastien Augustin; Aicha Bouaita; Crystel Bonnet; Manuel Simonutti; Valérie Forster; Serge Picaud; José-Alain Sahel; Marisol Corral-Debrinski
Optimized allotopic expression of the human mitochondrial ND4 prevents blindness in a rat model of mitochondrial dysfunction.
American journal of human genetics 2008;83(3):373-87.
2008: Patrice Fort; Abdoulaye Sene; Thomas Pannicke; Michel J Roux; Valérie Forster; Dominique MORNET; Uri Nudel; David Yaffe; Andreas Reichenbach; José-Alain Sahel; Alvaro Rendon
Kir4.1 and AQP4 associate with Dp71- and utrophin-DAPs complexes in specific and defined microdomains of Müller retinal glial cell membrane.
Glia 2008;56(6):597-610.
2008: Qing-Ping Wang; Firas Jammoul; Agnès Duboc; Jie Gong; Manuel Simonutti; Elisabeth Dubus; Cheryl M Craft; Wen Ye; José-Alain Sahel; Serge Picaud
Treatment of epilepsy: the GABA-transaminase inhibitor, vigabatrin, induces neuronal plasticity in the mouse retina.
The European journal of neuroscience 2008;27(8):2177-87.
2008: Jean-Francois GIRMENS; S Scheer; Emmanuel Héron; José-Alain Sahel; E Tournier-Lasserve; Michel Paques
Familial central retinal vein occlusion.
Eye (London, England) 2008;22(2):308-10.
2008: Francesco Bandello; Albert Augustin; José-Alain Sahel; Hicham Benhaddi; Cristina Negrini; Klaus Hieke; Gilles Berdeaux
Association between visual acuity and medical and non-medical costs in patients with wet age-related macular degeneration in France, Germany and Italy.
Drugs & aging 2008;25(3):255-68.
2007: José-Alain Sahel; Francesco Bandello; Albert Augustin; Frédérique Maurel; Cristina Negrini; Gilles Berdeaux
Health-related quality of life and utility in patients with age-related macular degeneration.
Archives of ophthalmology 2007;125(7):945-51.
2007: Michel Paques; Jean-Laurent Guyomard; Manuel Simonutti; Michel J Roux; Serge Picaud; Jean-François LeGargasson; José-Alain Sahel
Panretinal, high-resolution color photography of the mouse fundus.
Investigative ophthalmology & visual science 2007;48(6):2769-74.
2007: Crystel Bonnet; Valérie Kaltimbacher; Sami Ellouze; Sébastien Augustin; Paule Bénit; Valérie Forster; Pierre Rustin; José-Alain Sahel; Marisol Corral-Debrinski
Allotopic mRNA localization to the mitochondrial surface rescues respiratory chain defects in fibroblasts harboring mitochondrial DNA mutations affecting complex I or v subunits.
Rejuvenation research 2007;10(2):127-44.
2007: Salomon Y Cohen; Jean-François Korobelnik; Ramin Tadayoni; Gabriel Coscas; Catherine Creuzot-Garcher; F Devin; alain gaudric; M Mauget-Faysse; José-Alain Sahel; E Souied; M Weber; Gisele SOUBRANE
[Monitoring anti-VEGF drugs for treatment of exudative AMD].
Journal français d'ophtalmologie 2007;30(4):330-4.
2007: Thérese Cronin; Thierry Léveillard; José-Alain Sahel
Retinal degenerations: from cell signaling to cell therapy; pre-clinical and clinical issues.
Current gene therapy 2007;7(2):121-9.
2007: Jie Gong; Abdeljelil Jellali; Valérie Forster; Jérôme Mutterer; Elisabeth Dubus; Wilko D Altrock; José-Alain Sahel; Alvaro Rendon; Serge Picaud
The toxicity of the PrP106-126 prion peptide on cultured photoreceptors correlates with the prion protein distribution in the mammalian and human retina.
The American journal of pathology 2007;170(4):1314-24.
2007: Albert Augustin; José-Alain Sahel; Francesco Bandello; Roland Dardennes; Frédérique Maurel; Cristina Negrini; Klaus Hieke; Gilles Berdeaux
Anxiety and depression prevalence rates in age-related macular degeneration.
Investigative ophthalmology & visual science 2007;48(4):1498-503.
2007: Thierry Léveillard; Saddek Mohand-Saïd; José-Alain Sahel
[Retinal repair by transplantation of photoreceptor precursors].
Médecine sciences : M/S 2007;23(3):240-2.
2007: david gaucher; Jean-Armand Chiappore; Michel Pâques; Manuel Simonutti; Christian Boitard; José-Alain Sahel; Pascale Massin; Serge Picaud
Microglial changes occur without neural cell death in diabetic retinopathy.
Vision research 2007;47(5):612-23.
2007: Frédéric Chalmel; Thierry Léveillard; Céline Jaillard; Aurélie Lardenois; Naomi Berdugo; Emmanuelle Morel; Patrice Koehl; George Lambrou; Arne Holmgren; José-Alain Sahel; Olivier Poch
Rod-derived Cone Viability Factor-2 is a novel bifunctional-thioredoxin-like protein with therapeutic potential.
BMC molecular biology 2007;8():74.
2007: Crystel Bonnet; Valérie Kaltimbacher; Sami Ellouze; Valérie Forster; José-Alain Sahel; Marisol Corral-Debrinski
[mRNA localization to the mitochondrial surface: a tool to treat retinal pathologies due to mitochondrial DNA mutations].
Journal de la Société de biologie 2007;201(1):69-74.
2007: Mathias Fradot; Olivier Lorentz; Jean-Marie Wurtz; José-Alain Sahel; Thierry Léveillard
The loss of transcriptional inhibition by the photoreceptor-cell specific nuclear receptor (NR2E3) is not a necessary cause of enhanced S-cone syndrome.
Molecular vision 2007;13():594-601.
2007: Jérôme Roger; Olivier Goureau; José-Alain Sahel; xavier guillonneau
Use of suppression subtractive hybridization to identify genes regulated by ciliary neurotrophic factor in postnatal retinal explants.
Molecular vision 2007;13():206-19.
2006: Eric Wersinger; Yannick Schwab; José-Alain Sahel; Alvaro Rendon; David V Pow; Serge Picaud; Michel J Roux
The glutamate transporter EAAT5 works as a presynaptic receptor in mouse rod bipolar cells.
The Journal of physiology 2006;577(Pt 1):221-34.
2006: Jérôme Roger; Valérie Brajeul; Sylvie Thomasseau; Anni Hienola; José-Alain Sahel; xavier guillonneau; Olivier Goureau
Involvement of Pleiotrophin in CNTF-mediated differentiation of the late retinal progenitor cells.
Developmental biology 2006;298(2):527-39.
2006: Aurélie Lardenois; Frédéric Chalmel; Laurent Bianchetti; José-Alain Sahel; Thierry Léveillard; Olivier Poch
PromAn: an integrated knowledge-based web server dedicated to promoter analysis.
Nucleic acids research 2006;34(Web Server issue):W578-83.
2006: Valérie Kaltimbacher; Crystel Bonnet; Gaëlle Lecoeuvre; Valérie Forster; José-Alain Sahel; Marisol Corral-Debrinski
mRNA localization to the mitochondrial surface allows the efficient translocation inside the organelle of a nuclear recoded ATP6 protein.
RNA (New York, N.Y.) 2006;12(7):1408-17.
2006: Christine E Parc; Elodie Azan; Sébastien Bonnel; José-Alain Sahel; Josseline Kaplan; Charles Thirkill
Cone dysfunction as a paraneoplastic syndrome associated with retinal antigens approximating 40 kiloDalton.
Ophthalmic genetics 2006;27(2):57-61.
2006: Jie Gong; Abdeljelil Jellali; Jérôme Mutterer; José-Alain Sahel; Alvaro Rendon; Serge Picaud
Distribution of vesicular glutamate transporters in rat and human retina.
Brain research 2006;1082(1):73-85.
2006: Michel Paques; Manuel Simonutti; Michel J Roux; Serge Picaud; Etienne Levavasseur; Caren Bellman; José-Alain Sahel
High resolution fundus imaging by confocal scanning laser ophthalmoscopy in the mouse.
Vision research 2006;46(8-9):1336-45.
2006: Olivier Goureau; José-Alain Sahel
[Retinal stem cells: mechanism of differentiation and therapeutic application].
Pathologie-biologie 2006;54(2):64-71.
2006: Elise Balse; Luc-Henri Tessier; Valérie Forster; M J Roux; José-Alain Sahel; Serge Picaud
Glycine receptors in a population of adult mammalian cones.
The Journal of physiology 2006;571(Pt 2):391-401.
2006: S Scheer; S Boni; PO Barale; A Bourhis; Sébastien Bonnel; E Tuil; Jean-Francois GIRMENS; O Buil; Christophe Baudouin; Laurent Laroche; Jean-Philippe Nordmann; F Poisson; Jean-Michel Warnet; José-Alain Sahel
[Heavy silicone oil as internal tamponade for retinal detachment: efficacy and tolerance].
Journal français d'ophtalmologie 2006;29(2):129-35.
2006: Sylvain Hanein; Isabelle Perrault; Sylvie Gerber; Hélène Dollfus; Jean-Louis Dufier; Josué Feingold; Arnold Munnich; Shomi Bhattacharya; Josseline Kaplan; José-Alain Sahel; Jean-Michel Rozet; Thierry Leveillard
Disease-associated variants of the rod-derived cone viability factor (RdCVF) in Leber congenital amaurosis. Rod-derived cone viability variants in LCA.
Advances in experimental medicine and biology 2006;572():9-14.
2006: Jean-François Korobelnik; I Cochereau; Salomon Y Cohen; Gabriel Coscas; Catherine Creuzot-Garcher; F Devin; alain gaudric; A Mathis; Martine Mauget-Faÿsse; José-Alain Sahel; Gisele SOUBRANE; Eacute Souied; M Weber
[How to perform intravitreal injections].
Journal français d'ophtalmologie 2006;29(1):82-6.
2005: José-Alain Sahel
Saving cone cells in hereditary rod diseases: a possible role for rod-derived cone viability factor (RdCVF) therapy.
Retina (Philadelphia, Pa.) 2005;25(8 Suppl):S38-S39.
2005: Amélie Lecleire-Collet; Luc-Henri Tessier; Pascale Massin; Valérie Forster; Gérard Brasseur; José-Alain Sahel; Serge Picaud
Advanced glycation end products can induce glial reaction and neuronal degeneration in retinal explants.
The British journal of ophthalmology 2005;89(12):1631-3.
2005: Vincent Gualino; Salomon Y Cohen; Marie-Noëlle Delyfer; José-Alain Sahel; alain gaudric
Optical coherence tomography findings in tamoxifen retinopathy.
American journal of ophthalmology 2005;140(4):757-8.
2005: S Scheer; Christophe Morel; F Poisson; Sébastien Bonnel; Olivier Touzeau; José-Alain Sahel; Laurent Laroche
[Prevention of proliferative vitreoretinopathy using 5-FU heparin: clinical tolerance and efficacy].
Journal français d'ophtalmologie 2005;28(7):701-6.
2005: Géraldine Vallazza-Deschamps; David Cia; Jie Gong; Abdeljelil Jellali; Agnès Duboc; Valérie Forster; José-Alain Sahel; Luc-Henri Tessier; Serge Picaud
Excessive activation of cyclic nucleotide-gated channels contributes to neuronal degeneration of photoreceptors.
The European journal of neuroscience 2005;22(5):1013-22.
2005: Anne Galy; Michel Joseph Roux; José-Alain Sahel; Thierry Léveillard; Angela Giangrande
Rhodopsin maturation defects induce photoreceptor death by apoptosis: a fly model for RhodopsinPro23His human retinitis pigmentosa.
Human molecular genetics 2005;14(17):2547-57.
2005: Patrice Fort; Francisco J Estrada; Agnès Bordais; Dominique MORNET; José-Alain Sahel; Serge Picaud; Haydeé Rosas Vargas; Ramón Coral-Vázquez; Alvaro Rendon
The sarcoglycan-sarcospan complex localization in mouse retina is independent from dystrophins.
Neuroscience research 2005;53(1):25-33.
2005: Céline Fuchs; Valérie Forster; Elise Balse; José-Alain Sahel; Serge Picaud; Luc-Henri Tessier
Retinal-cell-conditioned medium prevents TNF-alpha-induced apoptosis of purified ganglion cells.
Investigative ophthalmology & visual science 2005;46(8):2983-91.
2005: Agnès Bordais; Francisco Bolaños-Jimenez; Patrice Fort; Carolina Varela; José-Alain Sahel; Serge Picaud; Alvaro Rendon
Molecular cloning and protein expression of Duchenne muscular dystrophy gene products in porcine retina.
Neuromuscular disorders : NMD 2005;15(7):476-87.
2005: Sophie Hamada; Jean-Michel Devys; Thanh Hoang Xuan; Stéphane Ganem; José-Alain Sahel; Françoise Héran; Benoît Plaud
Role of hyaluronidase in diplopia after peribulbar anesthesia for cataract surgery.
Ophthalmology 2005;112(5):879-82.
2005: Frédéric Chalmel; Aurélie Lardenois; julie thompson; Jean Muller; José-Alain Sahel; Thierry Léveillard; Olivier Poch
GOAnno: GO annotation based on multiple alignment.
Bioinformatics (Oxford, England) 2005;21(9):2095-6.
2005: David Cia; Agnès Bordais; Carolina Varela; Valérie Forster; José-Alain Sahel; Alvaro Rendon; Serge Picaud
Voltage-gated channels and calcium homeostasis in mammalian rod photoreceptors.
Journal of neurophysiology 2005;93(3):1468-75.
2005: José-Alain Sahel; Saddek Mohand-Said; Thierry Léveillard
[Neuroprotection of photoreceptor cells in rod-cone dystrophies: from cell therapy to cell signalling].
Comptes rendus biologies 2005;328(2):163-8.
2005: Géraldine Vallazza-Deschamps; Céline Fuchs; David Cia; Luc-Henri Tessier; José-Alain Sahel; Henri Dreyfus; Serge Picaud
Diltiazem-induced neuroprotection in glutamate excitotoxicity and ischemic insult of retinal neurons.
Documenta ophthalmologica. Advances in ophthalmology 2005;110(1):25-35.
2005: Marie-Noëlle Delyfer; Valérie Forster; Nathalie Neveux; Serge Picaud; Thierry Léveillard; José-Alain Sahel
Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina.
Molecular vision 2005;11():688-96.
2005: Marie-Noëlle Delyfer; Manuel Simonutti; Nathalie Neveux; Thierry Léveillard; José-Alain Sahel
Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST?
Molecular vision 2005;11():677-87.
2005: M Paques; P Massin; Sébastien Bonnel; José-Alain Sahel
[Angiogenesis and diabetic retinopathy: specific connections to neuroretinal tissue].
Journées annuelles de diabétologie de l'Hôtel-Dieu 2005;():33-7.
2005: Thierry Léveillard; Saddek Mohand-Saïd; Olivier Poch; José-Alain Sahel
[Rod-derived cone viability factor: a clue for therapy of retinitis pigmentosa?].
Médecine sciences : M/S 2005;21(1):22-4.
2005: Elise Balse; Luc-Henri Tessier; Céline Fuchs; Valérie Forster; José-Alain Sahel; Serge Picaud
Purification of mammalian cone photoreceptors by lectin panning and the enhancement of their survival in glia-conditioned medium.
Investigative ophthalmology & visual science 2005;46(1):367-74.
2004: S Scheer; Christophe Morel; Olivier Touzeau; José-Alain Sahel; Laurent Laroche
[Pharmacological adjuvants for surgical treatment of proliferative vitreoretinopathy].
Journal français d'ophtalmologie 2004;27(9 Pt 1):1051-9.
2004: Abigail S Hackam; Richelle Strom; Dongmei Liu; Jiang Qian; Chenwei Wang; Deborah C Otteson; Tushara L Gunatilaka; Ronald H Farkas; Itay Chowers; Masaaki Kageyama; Thierry Leveillard; José-Alain Sahel; Peter A Campochiaro; Giovanni Parmigiani; Donald J Zack
Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse.
Investigative ophthalmology & visual science 2004;45(9):2929-42.
2004: L Menu dit Huart; Olivier Lorentz; Olivier Goureau; Thierry Léveillard; José-Alain Sahel
DNA repair in the degenerating mouse retina.
Molecular and cellular neurosciences 2004;26(3):441-9.
2004: Thierry Léveillard; Saddek Mohand-Saïd; Olivier Lorentz; David Hicks; Anne-Claire Fintz; Emmanuelle Clérin; Manuel Simonutti; Valérie Forster; Nükhet Cavusoglu; Frédéric Chalmel; Pascal Dollé; Olivier Poch; George Lambrou; José-Alain Sahel
Identification and characterization of rod-derived cone viability factor.
Nature genetics 2004;36(7):755-9.
2004: Sébastien Bonnel; Saddek Mohand-Said; PO Barale; R De Nicola; José-Alain Sahel
[Hereditary retinal pathologies and AMD: new therapeutic perspectives].
Journal français d'ophtalmologie 2004;27(6 Pt 1):623-33.
2004: Marie-Noëlle Delyfer; Thierry Léveillard; Saddek Mohand-Saïd; David Hicks; Serge Picaud; José-Alain Sahel
Inherited retinal degenerations: therapeutic prospects.
Biology of the cell / under the auspices of the European Cell Biology Organization 2004;96(4):261-9.
2004: Agnès Duboc; Noëlle Hanoteau; Manuel Simonutti; Gabrielle Rudolf; Astrid Nehlig; José-Alain Sahel; Serge Picaud
Vigabatrin, the GABA-transaminase inhibitor, damages cone photoreceptors in rats.
Annals of neurology 2004;55(5):695-705.
2004: Thierry Léveillard; Saddek Mohand-Saïd; Anne-Claire Fintz; George Lambrou; José-Alain Sahel
The search for rod-dependent cone viability factors, secreted factors promoting cone viability.
Novartis Foundation symposium 2004;255():117-27; discussion 127-30, 177-8.
2003: Sébastien Bonnel; Saddek Mohand-Said; José-Alain Sahel
The aging of the retina.
Experimental gerontology 2003;38(8):825-31.
2003: Nükhet Cavusoglu; Danièle Thierse; Saddek Mohand-Saïd; Frédéric Chalmel; Olivier Poch; Alain Van Dorsselaer; José-Alain Sahel; Thierry Léveillard
Differential proteomic analysis of the mouse retina: the induction of crystallin proteins by retinal degeneration in the rd1 mouse.
Molecular & cellular proteomics : MCP 2003;2(8):494-505.
2003: fernanda porto; Isabelle Perrault; David Hicks; Jean-Michel Rozet; Noëlle Hanoteau; Sylvain Hanein; Josseline Kaplan; José-Alain Sahel
Prenatal human ocular degeneration occurs in Leber's Congenital Amaurosis (LCA1 and 2).
Advances in experimental medicine and biology 2003;533():59-68.
2002: José-Alain Sahel
[Retinitis pigmentosa: pathogenic progress and therapeutic hopes].
La Revue du praticien 2002;52(16):1745-7.
2002: Abdeljelil Jellali; Christiane Stussi-Garaud; Bruno Gasnier; Alvaro Rendon; José-Alain Sahel; Henri Dreyfus; Serge Picaud
Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina.
The Journal of comparative neurology 2002;449(1):76-87.
2002: fernanda porto; Isabelle Perrault; David Hicks; Jean-Michel Rozet; Noëlle Hanoteau; Sylvain Hanein; Josseline Kaplan; José-Alain Sahel
Prenatal human ocular degeneration occurs in Leber's congenital amaurosis (LCA2).
The journal of gene medicine 2002;4(4):390-6.
2001: X Luo; George Lambrou; José-Alain Sahel; David Hicks
Hypoglycemia induces general neuronal death, whereas hypoxia and glutamate transport blockade lead to selective retinal ganglion cell death in vitro.
Investigative ophthalmology & visual science 2001;42(11):2695-705.
2001: Saddek Mohand-Said; David Hicks; Thierry Léveillard; Serge Picaud; fernanda porto; José-Alain Sahel
Rod-cone interactions: developmental and clinical significance.
Progress in retinal and eye research 2001;20(4):451-67.
2001: José-Alain Sahel; Saddek Mohand-Said; Thierry Léveillard; David Hicks; Serge Picaud; Henri Dreyfus
Rod-cone interdependence: implications for therapy of photoreceptor cell diseases.
Progress in brain research 2001;131():649-61.
2000: Gaël Yvert; Katrin S Lindenberg; Serge Picaud; G Bernhard Landwehrmeyer; José-Alain Sahel; Jean-Louis Mandel
Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice.
Human molecular genetics 2000;9(17):2491-506.
2000: Saddek Mohand-Said; David Hicks; Henri Dreyfus; José-Alain Sahel
Selective transplantation of rods delays cone loss in a retinitis pigmentosa model.
Archives of ophthalmology 2000;118(6):807-11.
1999: M Frasson; José-Alain Sahel; M Fabre; Manuel Simonutti; Henri Dreyfus; Serge Picaud
Retinitis pigmentosa: rod photoreceptor rescue by a calcium-channel blocker in the rd mouse.
Nature medicine 1999;5(10):1183-7.
1998: Saddek Mohand-Said; A Deudon-Combe; David Hicks; Manuel Simonutti; Valérie Forster; Anne-Claire Fintz; Thierry Léveillard; Henri Dreyfus; José-Alain Sahel
Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(14):8357-62.
1997: Saddek Mohand-Said; M Weber; David Hicks; Henri Dreyfus; José-Alain Sahel
Intravitreal injection of ganglioside GM1 after ischemia reduces retinal damage in rats.
Stroke; a journal of cerebral circulation 1997;28(3):617-21; discussion 622.