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Hermann Sahm

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Tanja Hanke; Stephan Noack; Katharina Nöh; Tino Polen; Hermann Sahm; Wolfgang Wiechert; Stephanie Bringer; Michael Bott
Combined fluxomics and transcriptomics analysis of glucose catabolism via a partially cyclic pentose phosphate pathway in Gluconobacter oxydans 621H.
Tanja Hanke; Tino Polen; Janine Richhardt; Hermann Sahm; Stephanie Bringer; Michael Bott
Influence of oxygen limitation, absence of the cytochrome bc(1) complex and low pH on global gene expression in Gluconobacter oxydans 621H using DNA microarray technology.
Vera Krajewski; Petra Simic; Nigel J Mouncey; Stephanie Bringer; Hermann Sahm; Michael Bott
Metabolic engineering of Gluconobacter oxydans for improved growth rate and growth yield on glucose by elimination of gluconate formation.

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2013: Tanja Hanke; Stephan Noack; Katharina Nöh; Tino Polen; Hermann Sahm; Wolfgang Wiechert; Stephanie Bringer; Michael Bott
Combined fluxomics and transcriptomics analysis of glucose catabolism via a partially cyclic pentose phosphate pathway in Gluconobacter oxydans 621H.
Applied and environmental microbiology 2013;79(7):2336-48.
2012: Tanja Hanke; Tino Polen; Janine Richhardt; Hermann Sahm; Stephanie Bringer; Michael Bott
Influence of oxygen limitation, absence of the cytochrome bc(1) complex and low pH on global gene expression in Gluconobacter oxydans 621H using DNA microarray technology.
Journal of biotechnology 2012;157(3):359-72.
2010: Vera Krajewski; Petra Simic; Nigel J Mouncey; Stephanie Bringer; Hermann Sahm; Michael Bott
Metabolic engineering of Gluconobacter oxydans for improved growth rate and growth yield on glucose by elimination of gluconate formation.
Applied and environmental microbiology 2010;76(13):4369-76.
2009: Florian Heuser; Kay Marin; Björn Kaup; Stephanie Bringer; Hermann Sahm
Improving d-mannitol productivity of Escherichia coli: impact of NAD, CO2 and expression of a putative sugar permease from Leuconostoc pseudomesenteroides.
Metabolic engineering 2009;11(3):178-83.
2009: Tina Hölscher; Ute Schleyer; Marcel Merfort; Stephanie Bringer-Meyer; Helmut Görisch; Hermann Sahm
Glucose oxidation and PQQ-dependent dehydrogenases in Gluconobacter oxydans.
Journal of molecular microbiology and biotechnology 2009;16(1-2):6-13.
2009: Ramon Diesveld; Nadine Tietze; Oliver Fürst; Alexander Reth; Brigitte Bathe; Hermann Sahm; Lothar Eggeling
Activity of exporters of Escherichia coli in Corynebacterium glutamicum, and their use to increase L-threonine production.
Journal of molecular microbiology and biotechnology 2009;16(3-4):198-207.
2008: Ute Schleyer; Stephanie Bringer-Meyer; Hermann Sahm
An easy cloning and expression vector system for Gluconobacter oxydans.
International journal of food microbiology 2008;125(1):91-5.
2007: Carsten Bäumchen; Andreas H F J Roth; Rebekka Biedendieck; Marco Malten; Martin Follmann; Hermann Sahm; Stephanie Bringer-Meyer; Dieter Jahn
D-mannitol production by resting state whole cell biotrans-formation of D-fructose by heterologous mannitol and formate dehydrogenase gene expression in Bacillus megaterium.
Biotechnology journal 2007;2(11):1408-16.
2007: Roland Gande; Lynn Dover; Karin Krumbach; Gurdyal S Besra; Hermann Sahm; Tadao Oikawa; Lothar Eggeling
The two carboxylases of Corynebacterium glutamicum essential for fatty acid and mycolic acid synthesis.
Journal of bacteriology 2007;189(14):5257-64.
2007: Mathias Seidel; Luke Alderwick; Helen L Birch; Hermann Sahm; Lothar Eggeling; Gurdyal S Besra
Identification of a novel arabinofuranosyltransferase AftB involved in a terminal step of cell wall arabinan biosynthesis in Corynebacterianeae, such as Corynebacterium glutamicum and Mycobacterium tuberculosis.
The Journal of biological chemistry 2007;282(20):14729-40.
2007: Michael Stolz; Petra Peters-Wendisch; Helga Etterich; Tanja Gerharz; Robert Faurie; Hermann Sahm; Holger Fersterra; Lothar Eggeling
Reduced folate supply as a key to enhanced L-serine production by Corynebacterium glutamicum.
Applied and environmental microbiology 2007;73(3):750-5.
2007: Mathias Seidel; Luke Alderwick; Hermann Sahm; Gurdyal S Besra; Lothar Eggeling
Topology and mutational analysis of the single Emb arabinofuranosyltransferase of Corynebacterium glutamicum as a model of Emb proteins of Mycobacterium tuberculosis.
Glycobiology 2007;17(2):210-9.
2006: Eva Krings; Karin Krumbach; Brigitte Bathe; Ralf Kelle; Volker F Wendisch; Hermann Sahm; Lothar Eggeling
Characterization of myo-inositol utilization by Corynebacterium glutamicum: the stimulon, identification of transporters, and influence on L-lysine formation.
Journal of bacteriology 2006;188(23):8054-61.
2006: Luke Alderwick; Lynn Dover; Mathias Seidel; Roland Gande; Hermann Sahm; Lothar Eggeling; Gurdyal S Besra
Arabinan-deficient mutants of Corynebacterium glutamicum and the consequent flux in decaprenylmonophosphoryl-D-arabinose metabolism.
Glycobiology 2006;16(11):1073-81.
2006: Marcel Merfort; Ute Herrmann; Stephanie Bringer-Meyer; Hermann Sahm
High-yield 5-keto-D-gluconic acid formation is mediated by soluble and membrane-bound gluconate-5-dehydrogenases of Gluconobacter oxydans.
Applied microbiology and biotechnology 2006;73(2):443-51.
2006: Christoph Bremus; Ute Herrmann; Stephanie Bringer-Meyer; Hermann Sahm
The use of microorganisms in L-ascorbic acid production.
Journal of biotechnology 2006;124(1):196-205.
2006: Luke Alderwick; Mathias Seidel; Hermann Sahm; Gurdyal S Besra; Lothar Eggeling
Identification of a novel arabinofuranosyltransferase (AftA) involved in cell wall arabinan biosynthesis in Mycobacterium tuberculosis.
The Journal of biological chemistry 2006;281(23):15653-61.
2006: Marcel Merfort; Ute Herrmann; Seung-Wook Ha; Mustafa Elfari; Stephanie Bringer-Meyer; Helmut Görisch; Hermann Sahm
Modification of the membrane-bound glucose oxidation system in Gluconobacter oxydans significantly increases gluconate and 5-keto-D-gluconic acid accumulation.
Biotechnology journal 2006;1(5):556-63.
2005: Björn Kaup; Stephanie Bringer-Meyer; Hermann Sahm
D: -Mannitol formation from D: -glucose in a whole-cell biotransformation with recombinant Escherichia coli.
Applied microbiology and biotechnology 2005;69(4):397-403.
2005: Petra Peters-Wendisch; Michael Stolz; Helga Etterich; Nicole Kennerknecht; Hermann Sahm; Lothar Eggeling
Metabolic engineering of Corynebacterium glutamicum for L-serine production.
Applied and environmental microbiology 2005;71(11):7139-44.
2005: Jan Marienhagen; Nicole Kennerknecht; Hermann Sahm; Lothar Eggeling
Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum.
Journal of bacteriology 2005;187(22):7639-46.
2005: Luke Alderwick; Eva Radmacher; Mathias Seidel; Roland Gande; Paul G Hitchen; Howard R Morris; Anne Dell; Hermann Sahm; Lothar Eggeling; Gurdyal S Besra
Deletion of Cg-emb in corynebacterianeae leads to a novel truncated cell wall arabinogalactan, whereas inactivation of Cg-ubiA results in an arabinan-deficient mutant with a cell wall galactan core.
The Journal of biological chemistry 2005;280(37):32362-71.
2005: Eva Radmacher; Luke Alderwick; Gurdyal S Besra; Alistair K Brown; Kevin J C Gibson; Hermann Sahm; Lothar Eggeling
Two functional FAS-I type fatty acid synthases in Corynebacterium glutamicum.
Microbiology (Reading, England) 2005;151(Pt 7):2421-7.
2005: Eva Radmacher; Kathrin C Stansen; Gurdyal S Besra; Luke Alderwick; William N Maughan; Günter Hollweg; Hermann Sahm; Volker F Wendisch; Lothar Eggeling
Ethambutol, a cell wall inhibitor of Mycobacterium tuberculosis, elicits L-glutamate efflux of Corynebacterium glutamicum.
Microbiology (Reading, England) 2005;151(Pt 5):1359-68.
2005: Mustafa Elfari; Seung-Wook Ha; Christoph Bremus; Marcel Merfort; Viola Khodaverdi; Ute Herrmann; Hermann Sahm; Helmut Görisch
A Gluconobacter oxydans mutant converting glucose almost quantitatively to 5-keto-D-gluconic acid.
Applied microbiology and biotechnology 2005;66(6):668-74.
2005: Marianne Ernst; Björn Kaup; Michael Müller; Stephanie Bringer-Meyer; Hermann Sahm
Enantioselective reduction of carbonyl compounds by whole-cell biotransformation, combining a formate dehydrogenase and a (R)-specific alcohol dehydrogenase.
Applied microbiology and biotechnology 2005;66(6):629-34.
2004: Roman Netzer; Petra Peters-Wendisch; Lothar Eggeling; Hermann Sahm
Cometabolism of a nongrowth substrate: L-serine utilization by Corynebacterium glutamicum.
Applied and environmental microbiology 2004;70(12):7148-55.
2004: Roman Netzer; Malgorzata Krause; Doris Rittmann; Petra Peters-Wendisch; Lothar Eggeling; Volker F Wendisch; Hermann Sahm
Roles of pyruvate kinase and malic enzyme in Corynebacterium glutamicum for growth on carbon sources requiring gluconeogenesis.
Archives of microbiology 2004;182(5):354-63.
2004: Roland Gande; Kevin J C Gibson; Alistair K Brown; Karin Krumbach; Lynn Dover; Hermann Sahm; Susumu Shioyama; Tadao Oikawa; Gurdyal S Besra; Lothar Eggeling
Acyl-CoA carboxylases (accD2 and accD3), together with a unique polyketide synthase (Cg-pks), are key to mycolic acid biosynthesis in Corynebacterianeae such as Corynebacterium glutamicum and Mycobacterium tuberculosis.
The Journal of biological chemistry 2004;279(43):44847-57.
2004: Stefano Ricagno; Sigrid Grolle; Stephanie Bringer-Meyer; Hermann Sahm; Ylva Lindqvist; Gunter Schneider
Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution.
Biochimica et biophysica acta 2004;1698(1):37-44.
2004: Björn Kaup; Stephanie Bringer-Meyer; Hermann Sahm
Metabolic engineering of Escherichia coli: construction of an efficient biocatalyst for D-mannitol formation in a whole-cell biotransformation.
Applied microbiology and biotechnology 2004;64(3):333-9.
2004: Ute Herrmann; Marcel Merfort; M Jeude; Stephanie Bringer-Meyer; Hermann Sahm
Biotransformation of glucose to 5-keto-D-gluconic acid by recombinant Gluconobacter oxydans DSM 2343.
Applied microbiology and biotechnology 2004;64(1):86-90.
2003: Kevin J C Gibson; Lothar Eggeling; William N Maughan; Karin Krumbach; Sudagar S Gurcha; Jerome Nigou; Germain Puzo; Hermann Sahm; Gurdyal S Besra
Disruption of Cg-Ppm1, a polyprenyl monophosphomannose synthase, and the generation of lipoglycan-less mutants in Corynebacterium glutamicum.
The Journal of biological chemistry 2003;278(42):40842-50.
2003: Doris Rittmann; Steffen Schaffer; Volker F Wendisch; Hermann Sahm
Fructose-1,6-bisphosphatase from Corynebacterium glutamicum: expression and deletion of the fbp gene and biochemical characterization of the enzyme.
Archives of microbiology 2003;180(4):285-92.
2003: Jörn Kalinowski; Brigitte Bathe; Daniela Bartels; Nicole Bischoff; Michael Bott; Andreas Burkovski; Nicole Dusch; Lothar Eggeling; Bernhard J Eikmanns; Lars Gaigalat; Alexander Goesmann; Michael Hartmann; Klaus Huthmacher; Reinhard Krämer; Burkhard Linke; Alice C McHardy; Folker Meyer; Bettina Möckel; Walter Pfefferle; Alfred Pühler; Daniel A Rey; Christian Rückert; Oliver Rupp; Hermann Sahm; Volker F Wendisch; Iris Wiegräbe; Andreas Tauch
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.
Journal of biotechnology 2003;104(1-3):5-25.
2003: Lothar Eggeling; Hermann Sahm
New ubiquitous translocators: amino acid export by Corynebacterium glutamicum and Escherichia coli.
Archives of microbiology 2003;180(3):155-60.
2003: Takeru Ishige; Malgorzata Krause; Michael Bott; Volker F Wendisch; Hermann Sahm
The phosphate starvation stimulon of Corynebacterium glutamicum determined by DNA microarray analyses.
Journal of bacteriology 2003;185(15):4519-29.
2003: Christian Lange; Doris Rittmann; Volker F Wendisch; Michael Bott; Hermann Sahm
Global expression profiling and physiological characterization of Corynebacterium glutamicum grown in the presence of L-valine.
Applied and environmental microbiology 2003;69(5):2521-32.
2003: A Drysch; Mohamed El Massaoudi; Christina Mack; Ralf Takors; Albert de Graaf; Hermann Sahm
Production process monitoring by serial mapping of microbial carbon flux distributions using a novel Sensor Reactor approach: II--(13)C-labeling-based metabolic flux analysis and L-lysine production.
Metabolic engineering 2003;5(2):96-107.
2003: Tino Polen; Doris Rittmann; Volker F Wendisch; Hermann Sahm
DNA microarray analyses of the long-term adaptive response of Escherichia coli to acetate and propionate.
Applied and environmental microbiology 2003;69(3):1759-74.
2003: Björn Kaup; Stephanie Bringer-Meyer; Hermann Sahm
Metabolic engineering of Escherichia coli: construction of an efficient biocatalyst for D-mannitol formation in a whole-cell biotransformation.
Communications in agricultural and applied biological sciences 2003;68(2 Pt A):235-40.
2003: Gerald Hahn; Björn Kaup; Stephanie Bringer-Meyer; Hermann Sahm
A zinc-containing mannitol-2-dehydrogenase from Leuconostoc pseudomesenteroides ATCC 12291: purification of the enzyme and cloning of the gene.
Archives of microbiology 2003;179(2):101-7.
2002: Petra Peters-Wendisch; Roman Netzer; Lothar Eggeling; Hermann Sahm
3-Phosphoglycerate dehydrogenase from Corynebacterium glutamicum: the C-terminal domain is not essential for activity but is required for inhibition by L-serine.
Applied microbiology and biotechnology 2002;60(4):437-41.
2002: Bernd Moritz; Katharina Striegel; Albert de Graaf; Hermann Sahm
Changes of pentose phosphate pathway flux in vivo in Corynebacterium glutamicum during leucine-limited batch cultivation as determined from intracellular metabolite concentration measurements.
Metabolic engineering 2002;4(4):295-305.
2002: Petra Simic; Juliane Willuhn; Hermann Sahm; Lothar Eggeling
Identification of glyA (encoding serine hydroxymethyltransferase) and its use together with the exporter ThrE to increase L-threonine accumulation by Corynebacterium glutamicum.
Applied and environmental microbiology 2002;68(7):3321-7.
2002: Nicole Kennerknecht; Hermann Sahm; Ming-Ren Yen; Miroslav Pátek; Milton H Saier Jr; Lothar Eggeling
Export of L-isoleucine from Corynebacterium glutamicum: a two-gene-encoded member of a new translocator family.
Journal of bacteriology 2002;184(14):3947-56.
2002: Eva Radmacher; Adela Vaitsikova; Udo Burger; Karin Krumbach; Hermann Sahm; Lothar Eggeling
Linking central metabolism with increased pathway flux: L-valine accumulation by Corynebacterium glutamicum.
Applied and environmental microbiology 2002;68(5):2246-50.
2002: Ming-Ren Yen; Yi-Hsiung Tseng; Petra Simic; Hermann Sahm; Lothar Eggeling; Milton H Saier
The ubiquitous ThrE family of putative transmembrane amino acid efflux transporters.
Research in microbiology 2002;153(1):19-25.
2002: K M Nampoothiri; C Hoischen; Brigitte Bathe; Bettina Möckel; Walter Pfefferle; Karin Krumbach; Hermann Sahm; Lothar Eggeling
Expression of genes of lipid synthesis and altered lipid composition modulates L-glutamate efflux of Corynebacterium glutamicum.
Applied microbiology and biotechnology 2002;58(1):89-96.
2001: S Petersen; Christina Mack; Albert de Graaf; Christian-U Riedel; Bernhard J Eikmanns; Hermann Sahm
Metabolic consequences of altered phosphoenolpyruvate carboxykinase activity in Corynebacterium glutamicum reveal anaplerotic regulation mechanisms in vivo.
Metabolic engineering 2001;3(4):344-61.
2001: Christian-U Riedel; Doris Rittmann; P Dangel; Bettina Möckel; S Petersen; Hermann Sahm; Bernhard J Eikmanns
Characterization of the phosphoenolpyruvate carboxykinase gene from Corynebacterium glutamicum and significance of the enzyme for growth and amino acid production.
Journal of molecular microbiology and biotechnology 2001;3(4):573-83.
2001: Petra Simic; Hermann Sahm; Lothar Eggeling
L-threonine export: use of peptides to identify a new translocator from Corynebacterium glutamicum.
Journal of bacteriology 2001;183(18):5317-24.
2001: J W Schwinde; P F Hertz; Hermann Sahm; Bernhard J Eikmanns; A Guyonvarch
Lipoamide dehydrogenase from Corynebacterium glutamicum: molecular and physiological analysis of the lpd gene and characterization of the enzyme.
Microbiology (Reading, England) 2001;147(Pt 8):2223-31.
2001: A Bellmann; M Vrljić; Miroslav Pátek; Hermann Sahm; Reinhard Krämer; Lothar Eggeling
Expression control and specificity of the basic amino acid exporter LysE of Corynebacterium glutamicum.
Microbiology (Reading, England) 2001;147(Pt 7):1765-74.
2001: Thomas Hermann; Walter Pfefferle; C Baumann; E Busker; Steffen Schaffer; Michael Bott; Hermann Sahm; Nicole Dusch; Jörn Kalinowski; Alfred Pühler; Anne K Bendt; Reinhard Krämer; Andreas Burkovski
Proteome analysis of Corynebacterium glutamicum.
Electrophoresis 2001;22(9):1712-23.
2001: Petra Peters-Wendisch; B Schiel; Volker F Wendisch; E Katsoulidis; Bettina Möckel; Hermann Sahm; Bernhard J Eikmanns
Pyruvate carboxylase is a major bottleneck for glutamate and lysine production by Corynebacterium glutamicum.
Journal of molecular microbiology and biotechnology 2001;3(2):295-300.
2001: Albert de Graaf; Lothar Eggeling; Hermann Sahm
Metabolic engineering for L-lysine production by Corynebacterium glutamicum.
Advances in biochemical engineering/biotechnology 2001;73():9-29.
2001: Lothar Eggeling; Karin Krumbach; Hermann Sahm
L-glutamate efflux with Corynebacterium glutamicum: why is penicillin treatment or Tween addition doing the same?
Journal of molecular microbiology and biotechnology 2001;3(1):67-8.
2000: S Petersen; Albert de Graaf; Lothar Eggeling; M Möllney; Wolfgang Wiechert; Hermann Sahm
In vivo quantification of parallel and bidirectional fluxes in the anaplerosis of Corynebacterium glutamicum.
The Journal of biological chemistry 2000;275(46):35932-41.
2000: Sigrid Grolle; Stephanie Bringer-Meyer; Hermann Sahm
Isolation of the dxr gene of Zymomonas mobilis and characterization of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
FEMS microbiology letters 2000;191(1):131-7.
2000: Hermann Sahm; Lothar Eggeling; Albert de Graaf
Pathway analysis and metabolic engineering in Corynebacterium glutamicum.
Biological chemistry 2000;381(9-10):899-910.
2000: B Moritz; Katharina Striegel; Albert de Graaf; Hermann Sahm
Kinetic properties of the glucose-6-phosphate and 6-phosphogluconate dehydrogenases from Corynebacterium glutamicum and their application for predicting pentose phosphate pathway flux in vivo.
European journal of biochemistry / FEBS 2000;267(12):3442-52.
2000: Volker F Wendisch; Albert de Graaf; Hermann Sahm; Bernhard J Eikmanns
Quantitative determination of metabolic fluxes during coutilization of two carbon sources: comparative analyses with Corynebacterium glutamicum during growth on acetate and/or glucose.
Journal of bacteriology 2000;182(11):3088-96.
2000: Albert de Graaf; M Mahle; M Möllney; Wolfgang Wiechert; P Stahmann; Hermann Sahm
Determination of full 13C isotopomer distributions for metabolic flux analysis using heteronuclear spin echo difference NMR spectroscopy.
Journal of biotechnology 2000;77(1):25-35.
1999: M Vrljic; J Garg; A Bellmann; S Wachi; Roland Freudl; M J Malecki; Hermann Sahm; V J Kozina; Lothar Eggeling; M H Saier; L Eggeling; M H Saier
The LysE superfamily: topology of the lysine exporter LysE of Corynebacterium glutamicum, a paradyme for a novel superfamily of transmembrane solute translocators.
Journal of molecular microbiology and biotechnology 1999;1(2):327-36.
1999: P Vasicová; Miroslav Pátek; Jan Nesvera; Hermann Sahm; Bernhard J Eikmanns
Analysis of the Corynebacterium glutamicum dapA promoter.
Journal of bacteriology 1999;181(19):6188-91.
1999: U Neveling; Stephanie Bringer-Meyer; Hermann Sahm
Exceptional characteristics of heterotetrameric (alpha 2 beta 2) E1p of the pyruvate dehydrogenase complex from Zymomonas mobilis: expression from an own promoter and a lipoyl domain in E1 beta.
FEMS microbiology letters 1999;177(1):117-21.
1999: Albert de Graaf; Katharina Striegel; R M Wittig; B Laufer; G Schmitz; Wolfgang Wiechert; Georg A Sprenger; Hermann Sahm
Metabolic state of Zymomonas mobilis in glucose-, fructose-, and xylose-fed continuous cultures as analysed by 13C- and 31P-NMR spectroscopy.
Archives of microbiology 1999;171(6):371-85.
1999: Hermann Sahm; Lothar Eggeling
D-Pantothenate synthesis in Corynebacterium glutamicum and use of panBC and genes encoding L-valine synthesis for D-pantothenate overproduction.
Applied and environmental microbiology 1999;65(5):1973-9.
1999: I Maeting; G Schmidt; Hermann Sahm; José L Revuelta; Y D Stierhof; K-Peter Stahmann
Isocitrate lyase of Ashbya gossypii--transcriptional regulation and peroxisomal localization.
FEBS letters 1999;444(1):15-21.
1999: Dieter J Reinscheid; Stephanie Schnicke; Doris Rittmann; U Zahnow; Hermann Sahm; Bernhard J Eikmanns
Cloning, sequence analysis, expression and inactivation of the Corynebacterium glutamicum pta-ack operon encoding phosphotransacetylase and acetate kinase.
Microbiology (Reading, England) 1999;145 ( Pt 2)():503-13.
1999: A Marx; Bernhard J Eikmanns; Hermann Sahm; Albert de Graaf; Lothar Eggeling
Response of the central metabolism in Corynebacterium glutamicum to the use of an NADH-dependent glutamate dehydrogenase.
Metabolic engineering 1999;1(1):35-48.
1998: U Schörken; J Jia; Hermann Sahm; Georg A Sprenger; Gunter Schneider
Disruption of Escherichia coli transaldolase into catalytically active monomers: evidence against half-of-the-sites mechanism.
FEBS letters 1998;441(2):247-50.
1998: N Monschau; Hermann Sahm; K-Peter Stahmann
Threonine aldolase overexpression plus threonine supplementation enhanced riboflavin production in Ashbya gossypii.
Applied and environmental microbiology 1998;64(11):4283-90.
1998: U Neveling; Stephanie Bringer-Meyer; Hermann Sahm
Gene and subunit organization of bacterial pyruvate dehydrogenase complexes.
Biochimica et biophysica acta 1998;1385(2):367-72.
1998: A Wehrmann; B Phillipp; Hermann Sahm; Lothar Eggeling
Different modes of diaminopimelate synthesis and their role in cell wall integrity: a study with Corynebacterium glutamicum.
Journal of bacteriology 1998;180(12):3159-65.
1998: Petra Peters-Wendisch; C Kreutzer; Jörn Kalinowski; Miroslav Pátek; Hermann Sahm; Bernhard J Eikmanns
Pyruvate carboxylase from Corynebacterium glutamicum: characterization, expression and inactivation of the pyc gene.
Microbiology (Reading, England) 1998;144 ( Pt 4)():915-27.
1998: U Neveling; R Klasen; Stephanie Bringer-Meyer; Hermann Sahm
Purification of the pyruvate dehydrogenase multienzyme complex of Zymomonas mobilis and identification and sequence analysis of the corresponding genes.
Journal of bacteriology 1998;180(6):1540-8.
1998: Lothar Eggeling; S Oberle; Hermann Sahm
Improved L-lysine yield with Corynebacterium glutamicum: use of dapA resulting in increased flux combined with growth limitation.
Applied microbiology and biotechnology 1998;49(1):24-30.
1997: Georg A Sprenger; U Schörken; Thomas Wiegert; Sigrid Grolle; Albert de Graaf; Sean V Taylor; Tadhg P Begley; Stephanie Bringer-Meyer; Hermann Sahm
Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):12857-62.
1997: A Marx; Katharina Striegel; Albert de Graaf; Hermann Sahm; Lothar Eggeling
Response of the central metabolism of Corynebacterium glutamicum to different flux burdens.
Biotechnology and bioengineering 1997;56(2):168-80.
1997: Volker F Wendisch; M Spies; Dieter J Reinscheid; Stephanie Schnicke; Hermann Sahm; Bernhard J Eikmanns
Regulation of acetate metabolism in Corynebacterium glutamicum: transcriptional control of the isocitrate lyase and malate synthase genes.
Archives of microbiology 1997;168(4):262-9.
1997: Marc J Jakoby; M Tesch; Hermann Sahm; Reinhard Krämer; Andreas Burkovski
Isolation of the Corynebacterium glutamicum glnA gene encoding glutamine synthetase I.
FEMS microbiology letters 1997;154(1):81-8.
1997: Thomas Wiegert; Hermann Sahm; Georg A Sprenger
The substitution of a single amino acid residue (Ser-116 --> Asp) alters NADP-containing glucose-fructose oxidoreductase of Zymomonas mobilis into a glucose dehydrogenase with dual coenzyme specificity.
The Journal of biological chemistry 1997;272(20):13126-33.
1997: N Monschau; K-Peter Stahmann; Hermann Sahm; JB McNeil; Andrew L Bognar
Identification of Saccharomyces cerevisiae GLY1 as a threonine aldolase: a key enzyme in glycine biosynthesis.
FEMS microbiology letters 1997;150(1):55-60.
1997: K-Peter Stahmann; T Böddecker; Hermann Sahm
Regulation and properties of a fungal lipase showing interfacial inactivation by gas bubbles, or droplets of lipid or fatty acid.
European journal of biochemistry / FEBS 1997;244(1):220-5.
1997: Thomas Wiegert; Hermann Sahm; Georg A Sprenger
Expression of the Zymomonas mobilis gfo gene or NADP-containing glucose:fructose oxidoreductase (GFOR) in Escherichia coli. Formation of enzymatically active preGFOR but lack of processing into a stable periplasmic protein.
European journal of biochemistry / FEBS 1997;244(1):107-12.
1997: Volker F Wendisch; Albert de Graaf; Hermann Sahm
Accurate determination of 13C enrichments in nonprotonated carbon atoms of isotopically enriched amino acids by 1H nuclear magnetic resonance.
Analytical biochemistry 1997;245(2):196-202.
1996: M Vrljic; Hermann Sahm; Lothar Eggeling
A new type of transporter with a new type of cellular function: L-lysine export from Corynebacterium glutamicum.
Molecular microbiology 1996;22(5):815-26.
1996: Thomas Wiegert; Hermann Sahm; Georg A Sprenger
Export of the periplasmic NADP-containing glucose-fructose oxidoreductase of Zymomonas mobilis.
Archives of microbiology 1996;166(1):32-41.
1996: J Jia; W Huang; U Schörken; Hermann Sahm; Georg A Sprenger; Ylva Lindqvist; Gunter Schneider
Crystal structure of transaldolase B from Escherichia coli suggests a circular permutation of the alpha/beta barrel within the class I aldolase family.
Structure (London, England : 1993) 1996;4(6):715-24.
1996: P G Peters-Wendisch; Volker F Wendisch; Albert de Graaf; Bernhard J Eikmanns; Hermann Sahm
C3-carboxylation as an anaplerotic reaction in phosphoenolpyruvate carboxylase-deficient Corynebacterium glutamicum.
Archives of microbiology 1996;165(6):387-96.
1996: Hermann Sahm; Lothar Eggeling; Bernhard J Eikmanns; Reinhard Krämer
Construction of L-lysine-, L-threonine-, and L-isoleucine-overproducing strains of Corynebacterium glutamicum.
Annals of the New York Academy of Sciences 1996;782():25-39.
1996: Lothar Eggeling; Reinhard Krämer; M Vrljic; W Kronemeyer; Hermann Sahm
Transport mutants and transport genes of Corynebacterium glutamicum.
Annals of the New York Academy of Sciences 1996;782():191-201.
1996: Miroslav Pátek; Bernhard J Eikmanns; J Pátek; Hermann Sahm
Promoters from Corynebacterium glutamicum: cloning, molecular analysis and search for a consensus motif.
Microbiology (Reading, England) 1996;142 ( Pt 5)():1297-309.
1996: A Marx; Albert de Graaf; Wolfgang Wiechert; Lothar Eggeling; Hermann Sahm
Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing.
Biotechnology and bioengineering 1996;49(2):111-29.
1995: A Wehrmann; S Morakkabati; Reinhard Krämer; Hermann Sahm; Lothar Eggeling
Functional analysis of sequences adjacent to dapE of Corynebacterium glutamicum reveals the presence of aroP, which encodes the aromatic amino acid transporter.
Journal of bacteriology 1995;177(20):5991-3.
1995: G A Sprenger; U Schörken; Georg A Sprenger; Hermann Sahm
Transaldolase B of Escherichia coli K-12: cloning of its gene, talB, and characterization of the enzyme from recombinant strains.
Journal of bacteriology 1995;177(20):5930-6.
1995: M Vrljic; W Kronemeyer; Hermann Sahm; Lothar Eggeling
Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants.
Journal of bacteriology 1995;177(14):4021-7.
1995: P Weisser; Reinhard Krämer; Hermann Sahm; Georg A Sprenger
Functional expression of the glucose transporter of Zymomonas mobilis leads to restoration of glucose and fructose uptake in Escherichia coli mutants and provides evidence for its facilitator action.
Journal of bacteriology 1995;177(11):3351-4.
1995: Georg A Sprenger; U Schörken; G Sprenger; Hermann Sahm
Transketolase A of Escherichia coli K12. Purification and properties of the enzyme from recombinant strains.
European journal of biochemistry / FEBS 1995;230(2):525-32.
1995: R Klasen; Stephanie Bringer-Meyer; Hermann Sahm
Biochemical characterization and sequence analysis of the gluconate:NADP 5-oxidoreductase gene from Gluconobacter oxydans.
Journal of bacteriology 1995;177(10):2637-43.
1995: W Kronemeyer; N Peekhaus; Reinhard Krämer; Hermann Sahm; Lothar Eggeling
Structure of the gluABCD cluster encoding the glutamate uptake system of Corynebacterium glutamicum.
Journal of bacteriology 1995;177(5):1152-8.
1995: Bernhard J Eikmanns; D Rittmann; Hermann Sahm
Cloning, sequence analysis, expression, and inactivation of the Corynebacterium glutamicum icd gene encoding isocitrate dehydrogenase and biochemical characterization of the enzyme.
Journal of bacteriology 1995;177(3):774-82.
1995: K-Peter Stahmann; N Monschau; Hermann Sahm; A Koschel; M Gawronski; H Conrad; T Springer; F Kopp
Structural properties of native and sonicated cinerean, a beta- (1-->3) (1-->6)-D-glucan produced by Botrytis cinerea.
Carbohydrate research 1995;266(1):115-28.
1995: I G Reipen; Karl Poralla; Hermann Sahm; Georg A Sprenger
Zymomonas mobilis squalene-hopene cyclase gene (shc): cloning, DNA sequence analysis, and expression in Escherichia coli.
Microbiology (Reading, England) 1995;141 ( Pt 1)():155-61.
1994: H Loos; Reinhard Krämer; Hermann Sahm; Georg A Sprenger
Sorbitol promotes growth of Zymomonas mobilis in environments with high concentrations of sugar: evidence for a physiological function of glucose-fructose oxidoreductase in osmoprotection.
Journal of bacteriology 1994;176(24):7688-93.
1994: Luis Mateos; Agustín Pisabarro; Miroslav Pátek; M Malumbres; C Guerrero; Bernhard J Eikmanns; Hermann Sahm; Juan F Martín
Transcriptional analysis and regulatory signals of the hom-thrB cluster of Brevibacterium lactofermentum.
Journal of bacteriology 1994;176(23):7362-71.
1994: A Wehrmann; Lothar Eggeling; Hermann Sahm
Analysis of different DNA fragments of Corynebacterium glutamicum complementing dapE of Escherichia coli.
Microbiology (Reading, England) 1994;140 ( Pt 12)():3349-56.
1994: H Loos; U Ermler; Georg A Sprenger; Hermann Sahm
Crystallization and preliminary X-ray analysis of glucose-fructose oxidoreductase from Zymomonas mobilis.
Protein science : a publication of the Protein Society 1994;3(12):2447-9.
1994: Dieter J Reinscheid; Bernhard J Eikmanns; Hermann Sahm
Malate synthase from Corynebacterium glutamicum: sequence analysis of the gene and biochemical characterization of the enzyme.
Microbiology (Reading, England) 1994;140 ( Pt 11)():3099-108.
1994: B Möckel; Lothar Eggeling; Hermann Sahm
Threonine dehydratases of Corynebacterium glutamicum with altered allosteric control: their generation and biochemical and structural analysis.
Molecular microbiology 1994;13(5):833-42.
1994: Bernhard J Eikmanns; N Thum-Schmitz; Lothar Eggeling; K U Lüdtke; Hermann Sahm
Nucleotide sequence, expression and transcriptional analysis of the Corynebacterium glutamicum gltA gene encoding citrate synthase.
Microbiology (Reading, England) 1994;140 ( Pt 8)():1817-28.
1994: Dieter J Reinscheid; Bernhard J Eikmanns; Hermann Sahm
Characterization of the isocitrate lyase gene from Corynebacterium glutamicum and biochemical analysis of the enzyme.
Journal of bacteriology 1994;176(12):3474-83.
1994: Dieter J Reinscheid; W Kronemeyer; Lothar Eggeling; Bernhard J Eikmanns; Hermann Sahm
Stable Expression of hom-1-thrB in Corynebacterium glutamicum and Its Effect on the Carbon Flux to Threonine and Related Amino Acids.
Applied and environmental microbiology 1994;60(1):126-32.
1994: Miroslav Pátek; K Krumbach; Lothar Eggeling; Hermann Sahm
Leucine synthesis in Corynebacterium glutamicum: enzyme activities, structure of leuA, and effect of leuA inactivation on lysine synthesis.
Applied and environmental microbiology 1994;60(1):133-40.
1993: C Keilhauer; Lothar Eggeling; Hermann Sahm
Isoleucine synthesis in Corynebacterium glutamicum: molecular analysis of the ilvB-ilvN-ilvC operon.
Journal of bacteriology 1993;175(17):5595-603.
1993: S Horbach; Hermann Sahm; R Welle
Isoprenoid biosynthesis in bacteria: two different pathways?
FEMS microbiology letters 1993;111(2-3):135-40.
1993: J W Schwinde; N Thum-Schmitz; Bernhard J Eikmanns; Hermann Sahm
Transcriptional analysis of the gap-pgk-tpi-ppc gene cluster of Corynebacterium glutamicum.
Journal of bacteriology 1993;175(12):3905-8.
1993: K Sonntag; Lothar Eggeling; Albert de Graaf; Hermann Sahm
Flux partitioning in the split pathway of lysine synthesis in Corynebacterium glutamicum. Quantification by 13C- and 1H-NMR spectroscopy.
European journal of biochemistry / FEBS 1993;213(3):1325-31.
1993: H Loos; Hermann Sahm; Georg A Sprenger
Glucose-fructose oxidoreductase, a periplasmic enzyme of Zymomonas mobilis, is active in its precursor form.
FEMS microbiology letters 1993;107(2-3):293-8.
1993: Hermann Sahm; M Rohmer; Stephanie Bringer-Meyer; Georg A Sprenger; R Welle
Biochemistry and physiology of hopanoids in bacteria.
Advances in microbial physiology 1993;35():247-73.
1993: Bernhard J Eikmanns; Lothar Eggeling; Hermann Sahm
Molecular aspects of lysine, threonine, and isoleucine biosynthesis in Corynebacterium glutamicum.
Antonie van Leeuwenhoek 1993;64(2):145-63.
1992: B Möckel; Lothar Eggeling; Hermann Sahm
Functional and structural analyses of threonine dehydratase from Corynebacterium glutamicum.
Journal of bacteriology 1992;174(24):8065-72.
1992: K-Peter Stahmann; P Pielken; K L Schimz; Hermann Sahm
Degradation of Extracellular beta-(1,3)(1,6)-d-Glucan by Botrytis cinerea.
Applied and environmental microbiology 1992;58(10):3347-54.
1992: S D Feldmann; Hermann Sahm; Georg A Sprenger
Cloning and expression of the genes for xylose isomerase and xylulokinase from Klebsiella pneumoniae 1033 in Escherichia coli K12.
Molecular & general genetics : MGG 1992;234(2):201-10.
1992: C Cordes; B Möckel; Lothar Eggeling; Hermann Sahm
Cloning, organization and functional analysis of ilvA, ilvB and ilvC genes from Corynebacterium glutamicum.
Gene 1992;112(1):113-6.
1992: E R Börmann; Bernhard J Eikmanns; Hermann Sahm
Molecular analysis of the Corynebacterium glutamicum gdh gene encoding glutamate dehydrogenase.
Molecular microbiology 1992;6(3):317-26.
1991: B Schrumpf; A Schwarzer; Jörn Kalinowski; Alfred Pühler; Lothar Eggeling; Hermann Sahm
A functionally split pathway for lysine synthesis in Corynebacterium glutamicium.
Journal of bacteriology 1991;173(14):4510-6.
1991: Bernhard J Eikmanns; E Kleinertz; W Liebl; Hermann Sahm
A family of Corynebacterium glutamicum/Escherichia coli shuttle vectors for cloning, controlled gene expression, and promoter probing.
Gene 1991;102(1):93-8.
1991: Jörn Kalinowski; J Cremer; B Bachmann; Lothar Eggeling; Hermann Sahm; Alfred Pühler
Genetic and biochemical analysis of the aspartokinase from Corynebacterium glutamicum.
Molecular microbiology 1991;5(5):1197-204.
1991: Dieter J Reinscheid; Bernhard J Eikmanns; Hermann Sahm
Analysis of a Corynebacterium glutamicum hom gene coding for a feedback-resistant homoserine dehydrogenase.
Journal of bacteriology 1991;173(10):3228-30.
1991: I Uhlenbusch; Hermann Sahm; Georg A Sprenger
Expression of an L-alanine dehydrogenase gene in Zymomonas mobilis and excretion of L-alanine.
Applied and environmental microbiology 1991;57(5):1360-6.
1991: Bernhard J Eikmanns; M Metzger; Dieter J Reinscheid; M Kircher; Hermann Sahm
Amplification of three threonine biosynthesis genes in Corynebacterium glutamicum and its influence on carbon flux in different strains.
Applied microbiology and biotechnology 1991;34(5):617-22.
1990: M Reynen; I Reipen; Hermann Sahm; Georg A Sprenger
Construction of expression vectors for the gram-negative bacterium Zymomonas mobilis.
Molecular & general genetics : MGG 1990;223(2):335-41.
1990: U Ney; A J Macario; E Conway de Macario; Alexander Aivasidis; Siegfried M Schoberth; Hermann Sahm
Quantitative microbiological analysis of bacterial community shifts in a high-rate anaerobic bioreactor treating sulfite evaporator condensate.
Applied and environmental microbiology 1990;56(8):2389-98.
1989: U Schmid; K L Schimz; Hermann Sahm
Determination of intracellular pyridine nucleotide levels by bioluminescence using anaerobic bacteria as a model.
Analytical biochemistry 1989;180(1):17-23.
1989: E Menkel; G Thierbach; Lothar Eggeling; Hermann Sahm
Influence of increased aspartate availability on lysine formation by a recombinant strain of Corynebacterium glutamicum and utilization of fumarate.
Applied and environmental microbiology 1989;55(3):684-8.
1988: J Cremer; C Treptow; Lothar Eggeling; Hermann Sahm
Regulation of enzymes of lysine biosynthesis in Corynebacterium glutamicum.
Journal of general microbiology 1988;134(12):3221-9.
1988: P Pielken; K L Schimz; Lothar Eggeling; Hermann Sahm
Glucose metabolism in Xanthomonas campestris and influence of methionine on the carbon flow.
Canadian journal of microbiology 1988;34(12):1333-7.
1988: M Reynen; Hermann Sahm
Comparison of the structural genes for pyruvate decarboxylase in different Zymomonas mobilis strains.
Journal of bacteriology 1988;170(7):3310-3.
1988: E Heine-Dobbernack; Siegfried M Schoberth; Hermann Sahm
Relationship of Intracellular Coenzyme F(420) Content to Growth and Metabolic Activity of Methanobacterium bryantii and Methanosarcina barkeri.
Applied and environmental microbiology 1988;54(2):454-9.
1985: Lothar Eggeling; Hermann Sahm
The formaldehyde dehydrogenase of Rhodococcus erythropolis, a trimeric enzyme requiring a cofactor and active with alcohols.
European journal of biochemistry / FEBS 1985;150(1):129-34.
1983: G Brune; Siegfried M Schoberth; Hermann Sahm
Growth of a strictly anaerobic bacterium on furfural (2-furaldehyde).
Applied and environmental microbiology 1983;46(5):1187-92.
1980: Lothar Eggeling; Hermann Sahm
Regulation of alcohol oxidase synthesis in Hansenula polymorpha: oversynthesis during growth on mixed substrates and induction by methanol.
Archives of microbiology 1980;127(2):119-24.
1980: Lothar Eggeling; Hermann Sahm
Direct Enzymatic Assay for Alcohol Oxidase, Alcohol Dehydrogenase, and Formaldehyde Dehydrogenase in Colonies of Hansenula polymorpha.
Applied and environmental microbiology 1980;39(1):268-9.