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Shizuya Saika

Research Profile

Physiology

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Intraocular Lenses

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TOP 3
Nobuyuki Ishikawa; Takeshi Miyamoto; Yuko Hayashi; Shizuya Saika
Errors in the prediction of postoperative refraction following intraocular lens implantation in eyes with pseudoexfoliation syndrome.
Takayoshi Sumioka; Osamu Yamanaka; Kathleen C Flanders; Norihito Fujita; Hiroki Iwanishi; Winston W-Y Kao; Ai Kitano; Yuka Okada; Shizuya Saika
Impaired cornea wound healing in a tenascin C-deficient mouse model.
Shizuya Saika; Kumi Shirai; Takayoshi Sumioka; Osamu Yamanaka; Ai Kitano; Takeshi Miyamoto; Yuka Okada; Hideaki Kokado
Wakayama symposium: modulation of wound healing response in the corneal stroma by osteopontin and tenascin-C.

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All Publications

2013: Nobuyuki Ishikawa; Takeshi Miyamoto; Yuko Hayashi; Shizuya Saika
Errors in the prediction of postoperative refraction following intraocular lens implantation in eyes with pseudoexfoliation syndrome.
Journal of cataract and refractive surgery 2013;39(4):649-50.
2013: Takayoshi Sumioka; Osamu Yamanaka; Kathleen C Flanders; Norihito Fujita; Hiroki Iwanishi; Winston W-Y Kao; Ai Kitano; Yuka Okada; Shizuya Saika
Impaired cornea wound healing in a tenascin C-deficient mouse model.
Laboratory investigation; a journal of technical methods and pathology 2013;93(2):207-17.
2013: Shizuya Saika; Kumi Shirai; Takayoshi Sumioka; Osamu Yamanaka; Ai Kitano; Takeshi Miyamoto; Yuka Okada; Hideaki Kokado
Wakayama symposium: modulation of wound healing response in the corneal stroma by osteopontin and tenascin-C.
The ocular surface 2013;11(1):12-5.
2013: Yuanquan Yang; Yuka Okada; Shizuya Saika; Zheng Wang; Hua Yang; Peter S Reinach
Wakayama symposium: dependence of corneal epithelial homeostasis on transient receptor potential function.
The ocular surface 2013;11(1):8-11.
2012: Kentaro Suzuki; Chikako Yokoyama; Takiko Daikoku; Yujiro Higashi; Shin Mizoguchi; Shizuya Saika; Gen Yamada
Wakayama symposium: epithelial-mesenchymal interaction regulates tissue formation and characteristics: insights for corneal development.
The ocular surface 2012;10(4):217-20.
2012: Shizuya Saika
Wakayama symposium: current concepts of ocular surface cell biology.
The ocular surface 2012;10(4):210-1.
2011: Kazuto Terai; Noriko Terai; Jianhua Zhang; Chia-Yang Liu; Hongshan Liu; Shizuya Saika; Mindy K Call; Tai-Ichiro Chikama; Yasuhito Hayashi; Candace W-C Kao; Winston W-Y Kao
Crosstalk between TGF-beta and MAPK signaling during corneal wound healing.
Investigative ophthalmology & visual science 2011;52(11):8208-15.
2011: Nobuyuki Ishikawa; Takeshi Miyamoto; Yuka Okada; Shizuya Saika
Cell adhesion on explanted intraocular lenses part 2: experimental study of a surface-modified IOL in rabbits.
Journal of cataract and refractive surgery 2011;37(7):1339-42.
2011: Nobuyuki Ishikawa; Takeshi Miyamoto; Yuka Okada; Shizuya Saika
Cell adhesion on explanted intraocular lenses: part 1: analysis of explanted IOLs.
Journal of cataract and refractive surgery 2011;37(7):1333-8.
2011: Yuka Okada; Peter S Reinach; Kumi Shirai; Ai Kitano; Winston W-Y Kao; Kathleen C Flanders; Masayasu Miyajima; Hongshan Liu; Jianhua Zhang; Shizuya Saika
TRPV1 involvement in inflammatory tissue fibrosis in mice.
The American journal of pathology 2011;178(6):2654-64.
2011: Takayoshi Sumioka; Norihito Fujita; Ai Kitano; Yuka Okada; Shizuya Saika
Impaired angiogenic response in the cornea of mice lacking tenascin C.
Investigative ophthalmology & visual science 2011;52(5):2462-7.
2011: Kumi Shirai; Yasushi Nakamura; Yuka Okada; Shizuya Saika
Histopathological features in a case of peters' anomaly with acquired corneal staphyloma.
Case reports in ophthalmological medicine 2011;2011():418048.
2011: Norihito Fujita; Shuko Fujita; Shigeyuki Kon; Masato Matsuoka; Nahoko Ogata; Yuka Okada; Toshimitsu Uede; Shizuya Saika
Endogenous osteopontin involvement in laser-induced choroidal neovascularization in mice.
Investigative ophthalmology & visual science 2011;52(13):9310-5.
2010: Shizuya Saika
Editorial [Hot topic: Tissue fibrosis (Guest editor: Shizuya Saika)].
Endocrine, metabolic & immune disorders drug targets 2010;10(4):301.
2010: Shizuya Saika; Osamu Yamanaka; Takayoshi Sumioka; Yuka Okada; Takeshi Miyamoto; Kumi Shirai; Ai Kitano; Sai-ichi Tanaka
Transforming growth factor beta signal transduction: a potential target for maintenance/restoration of transparency of the cornea.
Eye & contact lens 2010;36(5):286-9.
2010: Yuka Okada; Peter S Reinach; Ai Kitano; Kumi Shirai; Winston W-Y Kao; Shizuya Saika
Neurotrophic keratopathy; its pathophysiology and treatment.
Histology and histopathology 2010;25(6):771-80.
2010: Kumi Shirai; Yuka Okada; Shizuya Saika
Immunohistochemical observation of anterior subcapsular cataract in eye with spontaneously regressed retinoblastoma.
Journal of cataract and refractive surgery 2010;36(3):503-7.
2010: Norihito Fujita; Shuko Fujita; Yuka Okada; Kyoko Fujita; Ai Kitano; Osamu Yamanaka; Takeshi Miyamoto; Shigeyuki Kon; Toshimitsu Uede; Susan R Rittling; David T Denhardt; Shizuya Saika
Impaired angiogenic response in the corneas of mice lacking osteopontin.
Investigative ophthalmology & visual science 2010;51(2):790-4.
2010: Ai Kitano; Yuka Okada; Osamu Yamanka; Kumi Shirai; Rajiv R Mohan; Shizuya Saika
Therapeutic potential of trichostatin A to control inflammatory and fibrogenic disorders of the ocular surface.
Molecular vision 2010;16():2964-73.
2010: Sai-ichi Tanaka; Takayoshi Sumioka; Norihito Fujita; Ai Kitano; Yuka Okada; Osamu Yamanaka; Kathleen C Flanders; Masayasu Miyajima; Shizuya Saika
Suppression of injury-induced epithelial-mesenchymal transition in a mouse lens epithelium lacking tenascin-C.
Molecular vision 2010;16():1194-205.
2009: Maki Shinozaki; Yuka Okada; Ai Kitano; Kazuo Ikeda; Shizuya Saika; Masahiro Shinozaki
Impaired cutaneous wound healing with excess granulation tissue formation in TNFalpha-null mice.
Archives of dermatological research 2009;301(7):531-7.
2009: Yuka Okada; Shizuya Saika; Kumi Shirai; Osamu Yamanaka; Ai Kitano; Zheng Wang; Hua Yang; Peter S Reinach
JNK MAPK signaling contributes in vivo to injury-induced corneal epithelial migration.
Ophthalmic research 2009;42(4):185-92.
2009: Shizuya Saika; Osamu Yamanaka; Yuka Okada; Sai-ichi Tanaka; Takeshi Miyamoto; Takayoshi Sumioka; Ai Kitano; Kumi Shirai; Kazuo Ikeda
TGF beta in fibroproliferative diseases in the eye.
Frontiers in bioscience (Scholar edition) 2009;1():376-90.
2009: Kyoko Fujita; Takeshi Miyamoto; Shizuya Saika
Sonic hedgehog: its expression in a healing cornea and its role in neovascularization.
Molecular vision 2009;15():1036-44.
2009: Shizuya Saika
[A journey for overcoming ischemic retinal diseases].
Nippon Ganka Gakkai zasshi 2009;113(1):3-4.
2009: Osamu Yamanaka; Ken-ichi Miyazaki; Ai Kitano; Shizuya Saika; Yuji Nakajima; Kazuo Ikeda
Suppression of injury-induced conjunctiva scarring by peroxisome proliferator-activated receptor gamma gene transfer in mice.
Investigative ophthalmology & visual science 2009;50(1):187-93.
2008: Ai Kitano; Osamu Yamanaka; Kazuo Ikeda; Iku Ishida-Nishikawa; Yuka Okada; Kumi Shirai; Shizuya Saika
Tetrandrine suppresses activation of human subconjunctival fibroblasts in vitro.
Current eye research 2008;33(7):559-65.
2008: Kyoko Fujita; Takeshi Miyamoto; Yuka Okada; Nobuyuki Ishikawa; Shizuya Saika
Expression pattern of sonic hedgehog and effect of topical mitomycin C on its expression in human ocular surface neoplasms.
Japanese journal of ophthalmology 2008;52(3):190-4.
2008: Ken-ichi Miyazaki; Yuka Okada; Osamu Yamanaka; Ai Kitano; Kazuo Ikeda; Shigeyuki Kon; Toshimitsu Uede; Susan R Rittling; David T Denhardt; Winston W-Y Kao; Shizuya Saika
Corneal wound healing in an osteopontin-deficient mouse.
Investigative ophthalmology & visual science 2008;49(4):1367-75.
2008: Shizuya Saika; Osamu Yamanaka; Kathleen C Flanders; Yuka Okada; Takeshi Miyamoto; Takayoshi Sumioka; Kumi Shirai; Ai Kitano; Ken-ichi Miyazaki; Sai-ichi Tanaka; Kazuo Ikeda
Epithelial-mesenchymal transition as a therapeutic target for prevention of ocular tissue fibrosis.
Endocrine, metabolic & immune disorders drug targets 2008;8(1):69-76.
2008: Shizuya Saika; Osamu Yamanaka; Takayoshi Sumioka; Takeshi Miyamoto; Ken-ichi Miyazaki; Yuka Okada; Ai Kitano; Kumi Shirai; Sai-ichi Tanaka; Kazuo Ikeda
Fibrotic disorders in the eye: targets of gene therapy.
Progress in retinal and eye research 2008;27(2):177-96.
2008: Osamu Yamanaka; Shizuya Saika; Kazuo Ikeda; Ken-Ichi Miyazaki; Ai Kitano; Yoshitaka Ohnishi
Connective tissue growth factor modulates extracellular matrix production in human subconjunctival fibroblasts and their proliferation and migration in vitro.
Japanese journal of ophthalmology 2008;52(1):8-15.
2008: Yuka Okada; Emiko Senba; Kumi Shirai; Tekashi Ueyama; Peter S Reinach; Shizuya Saika
Perturbed intraepithelial differentiation of corneal epithelium in c-Fos-null mice.
Japanese journal of ophthalmology 2008;52(1):1-7.
2008: Winston W-Y Kao; Ying Xia; Chia-Yang Liu; Shizuya Saika
Signaling pathways in morphogenesis of cornea and eyelid.
The ocular surface 2008;6(1):9-23.
2007: Ai Kitano; Shizuya Saika; Osamu Yamanaka; Kazuo Ikeda; Yuka Okada; Kumi Shirai; Peter S Reinach
Emodin suppression of ocular surface inflammatory reaction.
Investigative ophthalmology & visual science 2007;48(11):5013-22.
2007: Shizuya Saika
Yin and yang in cytokine regulation of corneal wound healing: roles of TNF-alpha.
Cornea 2007;26(9 Suppl 1):S70-4.
2007: Shizuya Saika; Osamu Yamanaka; Yuka Okada; Takeshi Miyamoto; Ai Kitano; Kathleen C Flanders; Yoshitaka Ohnishi; Yuji Nakajima; Winston W-Y Kao; Kazuo Ikeda
Effect of overexpression of PPARgamma on the healing process of corneal alkali burn in mice.
American journal of physiology. Cell physiology 2007;293(1):C75-86.
2007: Shuko Fujita; Shizuya Saika; Winston W-Y Kao; Kyoko Fujita; Takeshi Miyamoto; Kazuo Ikeda; Yuji Nakajima; Yoshitaka Ohnishi
Endogenous TNFalpha suppression of neovascularization in corneal stroma in mice.
Investigative ophthalmology & visual science 2007;48(7):3051-5.
2007: Shizuya Saika; Osamu Yamanaka; Iku Nishikawa-Ishida; Ai Kitano; Kathleen C Flanders; Yuka Okada; Yoshitaka Ohnishi; Yuji Nakajima; Kazuo Ikeda
Effect of Smad7 gene overexpression on transforming growth factor beta-induced retinal pigment fibrosis in a proliferative vitreoretinopathy mouse model.
Archives of ophthalmology 2007;125(5):647-54.
2007: Kohji Kinoshita; Yuji Iimuro; Kohji Otogawa; Shizuya Saika; Yutaka Inagaki; Yuji Nakajima; Norifumi Kawada; Jiro Fujimoto; Scott L Friedman; Kazuo Ikeda
Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats.
Gut 2007;56(5):706-14.
2007: Hee Jun Cho; Kyoung Eun Baek; Shizuya Saika; Moon-Jin Jeong; Jiyun Yoo
Snail is required for transforming growth factor-beta-induced epithelial-mesenchymal transition by activating PI3 kinase/Akt signal pathway.
Biochemical and biophysical research communications 2007;353(2):337-43.
2007: Shizuya Saika; Kumi Shirai; Osamu Yamanaka; Ken-Ichi Miyazaki; Yuka Okada; Ai Kitano; Kathleen C Flanders; Shigeyuki Kon; Toshimitsu Uede; Winston W-Y Kao; Susan R Rittling; David T Denhardt; Yoshitaka Ohnishi
Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium.
Laboratory investigation; a journal of technical methods and pathology 2007;87(2):130-8.
2007: Osamu Yamanaka; Shizuya Saika; Yoshitaka Ohnishi; Shokei Kim-Mitsuyama; Anil K Kamaraju; Kazuo Ikeda
Inhibition of p38MAP kinase suppresses fibrogenic reaction in conjunctiva in mice.
Molecular vision 2007;13():1730-9.
2007: Yuka Okada; Kazuo Ikeda; Osamu Yamanaka; Takeshi Miyamoto; Ai Kitano; Winston W-Y Kao; Shizuya Saika
TNFalpha suppression of corneal epithelium migration.
Molecular vision 2007;13():1428-35.
2007: Yuka Okada; Shizuya Saika; Takeshi Miyamoto; Kumi Shirai; Takashi Ueyama; Emiko Senba; Yoshitaka Ohnishi
AP-1 expression in ethanol-treated corneal epithelium in vivo.
Ophthalmic research 2007;39(2):84-91.
2006: Takeshi Miyamoto; Shizuya Saika; Takashi Ueyama; Yuka Okada; Kumi Shirai; Takayoshi Sumioka; Kyoko Fujita; Nobuyuki Ishiwaka; Yoshitaka Ohnishi
Cyclooxygenase 2 expression in rat corneas after ethanol exposure.
Journal of cataract and refractive surgery 2006;32(10):1736-40.
2006: Ai Kitano; Shizuya Saika; Osamu Yamanaka; Peter S Reinach; Kazuo Ikeda; Yuka Okada; Kumi Shirai; Yoshitaka Ohnishi
Genipin suppression of fibrogenic behaviors of the alpha-TN4 lens epithelial cell line.
Journal of cataract and refractive surgery 2006;32(10):1727-35.
2006: Ken-ichi Miyazaki; Shizuya Saika; Osamu Yamanaka; Yuka Okada; Yoshitaka Ohnishi
Treatment of eyelid epithelial neoplasm by targeting sonic hedgehog signaling: an experimental study.
Japanese journal of ophthalmology 2006;50(4):305-11.
2006: Osamu Yamanaka; Shizuya Saika; Kazuo Ikeda; Ken-Ichi Miyazaki; Yoshitaka Ohnishi; Akira Ooshima
Interleukin-7 modulates extracellular matrix production and TGF-beta signaling in cultured human subconjunctival fibroblasts.
Current eye research 2006;31(6):491-9.
2006: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Kathleen C Flanders; Yuka Okada; Takeshi Miyamoto; Ai Kitano; Akira Ooshima; Yuji Nakajima; Yoshitaka Ohnishi; Winston W-Y Kao
Loss of tumor necrosis factor alpha potentiates transforming growth factor beta-mediated pathogenic tissue response during wound healing.
The American journal of pathology 2006;168(6):1848-60.
2006: Yasuhiko Okajima; Shizuya Saika; Mitsuru Sawa
Effect of surface coating an acrylic intraocular lens with poly(2-methacryloyloxyethyl phosphorylcholine) polymer on lens epithelial cell line behavior.
Journal of cataract and refractive surgery 2006;32(4):666-71.
2006: Tadashi Kato; Shizuya Saika; Yoshitaka Ohnishi
Effects of the matrix metalloproteinase inhibitor GM6001 on the destruction and alteration of epithelial basement membrane during the healing of post-alkali burn in rabbit cornea.
Japanese journal of ophthalmology 2006;50(2):90-5.
2006: Shizuya Saika
TGFbeta pathobiology in the eye.
Laboratory investigation; a journal of technical methods and pathology 2006;86(2):106-15.
2006: Anita B Roberts; Fang Tian; Stacey DaCosta Byfield; Christina Stuelten; Akira Ooshima; Shizuya Saika; Kathleen C Flanders
Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.
Cytokine & growth factor reviews 2006;17(1-2):19-27.
2006: Ai Kitano; Shizuya Saika; Osamu Yamanaka; Kazuo Ikeda; Peter S Reinach; Yuji Nakajima; Yuka Okada; Kumi Shirai; Yoshitaka Ohnishi
Genipin suppresses subconjunctival fibroblast migration, proliferation and myofibroblast transdifferentiation.
Ophthalmic research 2006;38(6):355-60.
2006: Osamu Yamanaka; Kazuo Ikeda; Shizuya Saika; Ken-ichi Miyazaki; Akira Ooshima; Yoshitaka Ohnishi
Gene transfer of Smad7 modulates injury-induced conjunctival wound healing in mice.
Molecular vision 2006;12():841-51.
2006: Kumi Shirai; Shizuya Saika; Takeshi Tanaka; Yuka Okada; Kathleen C Flanders; Akira Ooshima; Yoshitaka Ohnishi
A new model of anterior subcapsular cataract: involvement of TGFbeta/Smad signaling.
Molecular vision 2006;12():681-91.
2006: Nobuhiro Izumi; Shinjiro Mizuguchi; Yutaka Inagaki; Shizuya Saika; Norifumi Kawada; Yuji Nakajima; Kiyotoshi Inoue; Shigefumi Suehiro; Scott L Friedman; Kazuo Ikeda
BMP-7 opposes TGF-beta1-mediated collagen induction in mouse pulmonary myofibroblasts through Id2.
American journal of physiology. Lung cellular and molecular physiology 2006;290(1):L120-6.
2006: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Kathleen C Flanders; Yoshitaka Ohnishi; Yuji Nakajima; Yasuteru Muragaki; Akira Ooshima
Adenoviral gene transfer of BMP-7, Id2, or Id3 suppresses injury-induced epithelial-to-mesenchymal transition of lens epithelium in mice.
American journal of physiology. Cell physiology 2006;290(1):C282-9.
2005: Yoshitaka Ohnishi; Shizuya Saika; Osamu Yamanaka; Yuka Okada; Kumi Shirai; Takeshi Miyamoto; Iku Nishikawa; Takeshi Tanaka; Kenichi Miyazaki
[Investigation of mechanism of cell proliferation regulation and its clinical application].
Nippon Ganka Gakkai zasshi 2005;109(12):865-83; discussion 884.
2005: Walid Khaled Barbour; Shizuya Saika; Takeshi Miyamoto; Yoshitaka Ohnishi
Biological compatibility of polymethyl methacrylate, hydrophilic acrylic and hydrophobic acrylic intraocular lenses.
Ophthalmic research 2005;37(5):255-61.
2005: Shizuya Saika; Osamu Yamanaka; Kazuo Ikeda; Shokei Kim-Mitsuyama; Kathleen C Flanders; Jiyun Yoo; Anita B Roberts; Iku Nishikawa-Ishida; Yoshitaka Ohnishi; Yasuteru Muragaki; Akira Ooshima
Inhibition of p38MAP kinase suppresses fibrotic reaction of retinal pigment epithelial cells.
Laboratory investigation; a journal of technical methods and pathology 2005;85(7):838-50.
2005: Kumi Shirai; Shizuya Saika; Yuka Okada; Takeshi Miyamoto; Takashi Ueyama; Yoshitaka Ohnishi
Transcriptional activation in lens epithelial cells following an ocular blunt trauma.
Journal of cataract and refractive surgery 2005;31(6):1226-30.
2005: Iku Ishida; Shizuya Saika; Yuka Okada; Yoshitaka Ohnishi
Growth factor deposition in anterior subcapsular cataract.
Journal of cataract and refractive surgery 2005;31(6):1219-25.
2005: Yasuhiko Okajima; Shizuya Saika; Mitsuru Sawa
[Effects of surface modification of intraocular lenses on foreign body reaction ].
Nippon Ganka Gakkai zasshi 2005;109(5):267-73.
2005: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Takeshi Miyamoto; Yoshitaka Ohnishi; Misako Sato; Yasuteru Muragaki; Akira Ooshima; Yuji Nakajima; Winston W-Y Kao; Kathleen C Flanders; Anita B Roberts
Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali.
The American journal of pathology 2005;166(5):1405-18.
2005: Shizuya Saika; Takeshi Miyamoto; Osamu Yamanaka; Tadashi Kato; Yoshitaka Ohnishi; Kathleen C Flanders; Kazuo Ikeda; Yuji Nakajima; Winston W-Y Kao; Misako Sato; Yasuteru Muragaki; Akira Ooshima
Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-kappaB, in treatment of corneal alkali burns in mice.
The American journal of pathology 2005;166(5):1393-403.
2005: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Kathleen C Flanders; Yuji Nakajima; Takeshi Miyamoto; Yoshitaka Ohnishi; Winston W-Y Kao; Yasuteru Muragaki; Akira Ooshima
Therapeutic effects of adenoviral gene transfer of bone morphogenic protein-7 on a corneal alkali injury model in mice.
Laboratory investigation; a journal of technical methods and pathology 2005;85(4):474-86.
2005: Yasuhito Hayashi; Chia-Yang Liu; James J Jester; Miyuki Hayashi; I-Jong Wang; James L Funderburgh; Shizuya Saika; Peter J Roughley; Candace W-C Kao; Winston W-Y Kao
Excess biglycan causes eyelid malformation by perturbing muscle development and TGF-alpha signaling.
Developmental biology 2005;277(1):222-34.
2004: Takeshi Miyamoto; Shizuya Saika; Yuka Okada; Yoshiji Kawashima; Takayoshi Sumioka; Norihito Fujita; Yoshitaka Suzuki; Akio Yamanaka; Yoshitaka Ohnishi
Expression of cyclooxygenase-2 in corneal cells after photorefractive keratectomy and laser in situ keratomileusis in rabbits.
Journal of cataract and refractive surgery 2004;30(12):2612-7.
2004: Shizuya Saika
TGF-beta signal transduction in corneal wound healing as a therapeutic target.
Cornea 2004;23(8 Suppl):S25-30.
2004: Shizuya Saika; Satoko Kono-Saika; Takeshi Tanaka; Osamu Yamanaka; Yoshitaka Ohnishi; Misako Sato; Yasuteru Muragaki; Akira Ooshima; Jiyun Yoo; Kathleen C Flanders; Anita B Roberts
Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice.
Laboratory investigation; a journal of technical methods and pathology 2004;84(10):1245-58.
2004: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Misako Sato; Yasuteru Muragaki; Yoshitaka Ohnishi; Akira Ooshima; Yuji Nakajima; Kazuhiko Namikawa; Hiroshi Kiyama; Kathleen C Flanders; Anita B Roberts
Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial-mesenchymal transition of lens epithelium in mice.
Laboratory investigation; a journal of technical methods and pathology 2004;84(10):1259-70.
2004: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Walid Khaled Barbour; Yoshitaka Ohnishi; Akira Ooshima
Accumulation of thrombospondin-1 in post-operative capsular fibrosis and its down-regulation in lens cells during lens fiber formation.
Experimental eye research 2004;79(2):147-56.
2004: Shizuya Saika; Yasuteru Muragaki; Yuka Okada; Takeshi Miyamoto; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Sonic hedgehog expression and role in healing corneal epithelium.
Investigative ophthalmology & visual science 2004;45(8):2577-85.
2004: Takeshi Tanaka; Shizuya Saika; Yoshitaka Ohnishi; Akira Ooshima; John W McAvoy; Chia-Yang Liu; Mohamad Azhar; Thomas Doetschman; Winston W-Y Kao
Fibroblast growth factor 2: roles of regulation of lens cell proliferation and epithelial-mesenchymal transition in response to injury.
Molecular vision 2004;10():462-7.
2004: Walid Khaled Barbour; Shizuya Saika; Takeshi Miyamoto; Kiyomi Ohkawa; Hirotoshi Utsunomiya; Yoshitaka Ohnishi
Expression patterns of beta1-related alpha integrin subunits in murine lens during embryonic development and wound healing.
Current eye research 2004;29(1):1-10.
2004: Kumi Shirai; Shizuya Saika; Yuka Okada; Emiko Senba; Yoshitaka Ohnishi
Expression of c-Fos and c-Jun in developing mouse lens.
Ophthalmic research 2004;36(4):226-30.
2004: Sai-ichi Tanaka; Shizuya Saika; Manabu Tamura; Yoshitaka Ohnishi
Histological observation of complete closure of anterior capsulotomy in 2 cases.
Journal of cataract and refractive surgery 2004;30(6):1374-7.
2004: Frank J Lovicu; Philipp Steven; Shizuya Saika; John W McAvoy
Aberrant lens fiber differentiation in anterior subcapsular cataract formation: a process dependent on reduced levels of Pax6.
Investigative ophthalmology & visual science 2004;45(6):1946-53.
2004: Shizuya Saika
Relationship between posterior capsule opacification and intraocular lens biocompatibility.
Progress in retinal and eye research 2004;23(3):283-305.
2004: Takeshi Miyamoto; Shizuya Saika; Akio Yamanaka; Yuka Okada; Yoshitaka Ohnishi
Deposition of silicone oil droplets in the residual anterior lens capsule after vitrectomy and lensectomy in rabbits.
The British journal of ophthalmology 2004;88(5):703-7.
2004: Shizuya Saika; Yuka Okada; Takeshi Miyamoto; Osamu Yamanaka; Yoshitaka Ohnishi; Akio Yamanaka; Akira Ooshima
Protein expression pattern of collagen type XV in mouse cornea.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2004;242(5):432-6.
2004: Takeshi Miyamoto; Shizuya Saika; Yuka Okada; Iku Ishida-Nishikawa; Takayoshi Sumioka; Norihito Fujita; Yoshitaka Ohnishi
Topical exposure of mitomycin C reduces opacification of the residual anterior lens capsule and lenticular regeneration after vitrectomy and lensectomy in rabbits.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2004;242(4):327-31.
2004: Kumi Shirai; Shizuya Saika; Yuka Okada; Seiji Oda; Yoshitaka Ohnishi
Histology and immunohistochemistry of fibrous posterior capsule opacification in an infant.
Journal of cataract and refractive surgery 2004;30(2):523-6.
2004: Shizuya Saika; Satoko Kono-Saika; Yoshitaka Ohnishi; Misako Sato; Yasuteru Muragaki; Akira Ooshima; Kathleen C Flanders; Jiyun Yoo; Mario A Anzano; Chia-Yang Liu; Winston W-Y Kao; Anita B Roberts
Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury.
The American journal of pathology 2004;164(2):651-63.
2004: Takeshi Tanaka; Shizuya Saika; Natsuko Hashizume; Yoshitaka Ohnishi
Brown haze in an Allergan SI-40NB silicone intraocular lens.
Journal of cataract and refractive surgery 2004;30(1):250-2.
2004: Shizuya Saika; Yuka Okada; Takeshi Miyamoto; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Chia-Yang Liu; Daniel Weng; Winston W-Y Kao
Role of p38 MAP kinase in regulation of cell migration and proliferation in healing corneal epithelium.
Investigative ophthalmology & visual science 2004;45(1):100-9.
2003: Misako Sato; Yasuteru Muragaki; Shizuya Saika; Anita B Roberts; Akira Ooshima
Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction.
The Journal of clinical investigation 2003;112(10):1486-94.
2003: Kumi Shirai; Shizuya Saika; Yuka Okada; Emiko Senba; Yoshitaka Ohnishi
Transcription activation in lens epithelial cells after anterior capsule rubbing in rats. expression of c-Fos.
Journal of cataract and refractive surgery 2003;29(8):1601-4.
2003: Kiyomi Ohkawa; Shizuya Saika; Yuko Hayashi; Akihiko Tawara; Yoshitaka Ohnishi
Cornea with Peters' anomaly: perturbed differentiation of corneal cells and abnormal extracellular matrix in the corneal stroma.
Japanese journal of ophthalmology 2003;47(4):327-31.
2003: Shizuya Saika; Takeshi Miyamoto; Yoshitaka Ohnishi
Histology of anterior capsule opacification with a polyHEMA/HOHEXMA hydrophilic hydrogel intraocular lens compared to poly(methyl methacrylate), silicone, and acrylic lenses.
Journal of cataract and refractive surgery 2003;29(6):1198-203.
2003: Shizuya Saika; Takeshi Miyamoto; Sai-ichi Tanaka; Takeshi Tanaka; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima; Toshiyuki Ishiwata; Goro Asano; Tai-Ichiro Chikama; Atsushi Shiraishi; Chia-Yang Liu; Candace W-C Kao; Winston W-Y Kao
Response of lens epithelial cells to injury: role of lumican in epithelial-mesenchymal transition.
Investigative ophthalmology & visual science 2003;44(5):2094-102.
2003: Yuka Okada; Shizuya Saika; Kumi Shirai; Yoshitaka Ohnishi; Emiko Senba
Expression of AP-1 (c-fos/c-jun) in developing mouse corneal epithelium.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2003;241(4):330-3.
2003: Yuka Okada; Shizuya Saika; Kumi Shirai; Natsuko Hashizume; Takeshi Miyamoto; Osamu Yamanaka; Yoshitaka Ohnishi; Masayasu Miyajima; Emiko Senba
AP-1 (c-Fos/c-Jun) is required for corneal epithelial spreading.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2003;241(4):327-9.
2003: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Osteopontin: a component of matrix in capsular opacification and subcapsular cataract.
Investigative ophthalmology & visual science 2003;44(4):1622-8.
2003: Osamu Yamanaka; Shizuya Saika; Yuka Okada; Akira Ooshima; Yoshitaka Ohnishi
Effects of interferon-gamma on human subconjunctival fibroblasts in the presence of TGFbeta1: reversal of TGFbeta-stimulated collagen production.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2003;241(2):116-24.
2003: Takeshi Miyamoto; Shizuya Saika; Akio Yamanaka; Yoshiji Kawashima; Yoshitaka Suzuki; Yoshitaka Ohnishi
Wound healing in rabbit corneas after photorefractive keratectomy and laser in situ keratomileusis.
Journal of cataract and refractive surgery 2003;29(1):153-8.
2002: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Kumi Shirai; Yoshitaka Ohnishi; Akira Ooshima; J W McAvoy
TGFbeta-Smad signalling in postoperative human lens epithelial cells.
The British journal of ophthalmology 2002;86(12):1428-33.
2002: Hélène Paradis; Chia-Yang Liu; Shizuya Saika; Mohamad Azhar; Thomas Doetschman; William V Good; R Nayak; N Laver; Candace W-C Kao; Winston W-Y Kao; Robert L Gendron
Tubedown-1 in remodeling of the developing vitreal vasculature in vivo and regulation of capillary outgrowth in vitro.
Developmental biology 2002;249(1):140-55.
2002: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Lens epithelial cell death after cataract surgery.
Journal of cataract and refractive surgery 2002;28(8):1452-6.
2002: Shizuya Saika; Yuko Hayashi; Takeshi Miyamoto; Takeshi Yoshitomi; Yoshitaka Ohnishi
Multiple retinal holes in the macular region: a case report.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2002;240(7):578-9.
2002: Sai-ichi Tanaka; Shizuya Saika; Shunsaku Ohmi; Takeshi Miyamoto; Iku Ishida; Yuka Okada; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Cellular fibronectin, but not collagens, disappears in the central posterior capsules during healing after lens extraction and IOL implantation in rabbits.
Japanese journal of ophthalmology 2002;46(2):147-52.
2002: Shizuya Saika; Yoshitaka Ohnishi; Akira Ooshima; Chia-Yang Liu; Winston W-Y Kao
Epithelial repair: roles of extracellular matrix.
Cornea 2002;21(2 Suppl 1):S23-9.
2002: Shizuya Saika; Takeshi Miyamoto; Takeshi Tanaka; Yoshitaka Ohnishi; Akira Ooshima; Wataru Kimura
Histopathology of anterior lens capsules in vitrectomized eyes with tamponade by silicone oil.
Journal of cataract and refractive surgery 2002;28(2):376-8.
2001: Shizuya Saika; S Saika; Chia-Yang Liu; Mohamad Azhar; L Philip Sanford; Thomas Doetschman; Robert L Gendron; Candace W-C Kao; Winston W-Y Kao
TGFbeta2 in corneal morphogenesis during mouse embryonic development.
Developmental biology 2001;240(2):419-32.
2001: Shizuya Saika; Takeshi Miyamoto; Takeshi Tanaka; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Collagens XII and XIV (FACITs) in capsular opacification and in cultured lens epithelial cells.
Current eye research 2001;23(6):463-8.
2001: Shizuya Saika; Takeshi Miyamoto; Takeshi Tanaka; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Latent TGFbeta binding protein-1 and fibrillin-1 in human capsular opacification and in cultured lens epithelial cells.
The British journal of ophthalmology 2001;85(11):1362-6.
2001: Kumi Shirai; Yuka Okada; Shizuya Saika; Emiko Senba; Yoshitaka Ohnishi
Expression of transcription factor AP-1 in rat lens epithelial cells during wound repair.
Experimental eye research 2001;73(4):461-8.
2001: Iku Ishida; Shizuya Saika; Yoshitaka Ohnishi
Effect of minoxidil on rabbit lens epithelial cell behavior in vitro and in situ.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2001;239(10):770-7.
2001: Shizuya Saika; T Tanaka; Takeshi Miyamoto; Yoshitaka Ohnishi
Surgical posterior vitreous detachment combined with gas/air tamponade for treating macular edema associated with branch retinal vein occlusion: retinal tomography and visual outcome.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2001;239(10):729-32.
2001: Natsuko Hashizume; Shizuya Saika; Yuka Okada; Takeshi Miyamoto; K Shimizu; Yoshitaka Ohnishi
Effects of antiinflammatory drugs on migration of the rabbit corneal epithelium.
Journal of cataract and refractive surgery 2001;27(9):1499-502.
2001: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Takeshi Tanaka; Yuka Okada; Y Nagane; Kumi Shirai; Yoshitaka Ohnishi
Comparison of Scheimpflug images of posterior capsule opacification and histological findings in rabbits and humans.
Journal of cataract and refractive surgery 2001;27(7):1088-92.
2001: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Yuka Okada; Yoshitaka Ohnishi; Akira Ooshima
Lens epithelial cell regeneration of a capsule-like structure during postoperative healing in rabbits.
Journal of cataract and refractive surgery 2001;27(7):1076-8.
2001: Shizuya Saika; Osamu Yamanaka; Y Baba; Yoshiji Kawashima; Kumi Shirai; Takeshi Miyamoto; Yuka Okada; Yoshitaka Ohnishi; Akira Ooshima
Accumulation of latent transforming growth factor-beta binding protein-1 and TGF beta 1 in extracellular matrix of filtering bleb and of cultured human subconjunctival fibroblasts.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2001;239(3):234-41.
2001: I Wang; Candace W-C Kao; C Liu; Shizuya Saika; P M Nishina; J P Sundberg; R S Smith; Winston W-Y Kao
Characterization of Corn1 mice: Alteration of epithelial and stromal cell gene expression.
Molecular vision 2001;7():20-6.
2001: Yuka Okada; Shizuya Saika; Kumi Shirai; Natsuko Hashizume; Osamu Yamanaka; Yoshitaka Ohnishi; Emiko Senba
Disappearance of desmosomal components in rat corneal epithelium during wound healing.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde 2001;215(1):61-5.
2000: Yoshiji Kawashima; Shizuya Saika; Takeshi Miyamoto; Osamu Yamanaka; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi
Matrix metalloproteinases and tissue inhibitors of metalloproteinases of fibrous humans lens capsules with intraocular lenses.
Current eye research 2000;21(6):962-7.
2000: Shizuya Saika; A Minamide; Takeshi Tanaka; Takeshi Miyamoto; Yuka Okada; Yoshiji Kawashima; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Expression of involucrin by ocular surface epithelia of patients with benign and malignant disorders.
Current eye research 2000;21(5):877-85.
2000: Shizuya Saika; Takeshi Miyamoto; Yoshiji Kawashima; K Jinza; Yuka Okada; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Alterations in ultrastructure and c-met expression in a case of ocular epithelial dysplasia following topical mitomycin C treatment.
Japanese journal of ophthalmology 2000;44(6):639-42.
2000: K Jinza; Shizuya Saika; K Kin; Yoshitaka Ohnishi
Relationship between formation of a filtering bleb and an intrascleral aqueous drainage route after trabeculectomy: evaluation using ultrasound biomicroscopy.
Ophthalmic research 2000;32(5):240-3.
2000: Shizuya Saika; Takeshi Miyamoto; Yuka Okada; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Transforming growth factor-beta isoform proteins in cell and matrix deposits on intraocular lenses.
Journal of cataract and refractive surgery 2000;26(5):709-15.
2000: Shizuya Saika; Atsushi Shiraishi; Chia-Yang Liu; James L Funderburgh; Candace W-C Kao; Richard L Converse; Winston W-Y Kao
Role of lumican in the corneal epithelium during wound healing.
The Journal of biological chemistry 2000;275(4):2607-12.
2000: Shizuya Saika; Yuka Okada; Kumi Shirai; Yoshiji Kawashima; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Immunolocalization of c-Fos and c-Jun in rat ocular surface epithelium.
Ophthalmic research 2000;32(1):9-12.
1999: Shunsaku Ohmi; S Tanaka; Shizuya Saika; Y Ohnishi
Silicone and poly(methyl methacrylate) lens decentration associated with asymmetric capsule shrinkage in rabbits.
Journal of cataract and refractive surgery 1999;25(8):1147-50.
1999: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; T Katoh; K Shirai; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Immunolocalization of transcription factor AP1 in human ocular surface epithelia.
Current eye research 1999;18(6):477-89.
1999: Shizuya Saika; Yoshiji Kawashima; Yuka Okada; K Ohkawa; Osamu Yamanaka; T Katoh; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Immunohistochemical and ultrastructural analysis of dysplastic epithelium of human ocular surface: basement membrane and intermediate filament.
Cornea 1999;18(3):343-52.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Pathological findings in lens capsule and silicone intraocular lens extracted from eye with chronic infectious endophthalmitis.
Japanese journal of ophthalmology 1998;42(6):456-60.
1998: Shizuya Saika; M Shimezaki; Kiyomi Ohkawa; Yuka Okada; Akihiko Tawara; Yoshitaka Ohnishi; Akira Ooshima; M Kimura; N Kurumatani; H Naka; T Awata; Winston W-Y Kao
Ultrastructural examination of corneal epithelium of spontaneously obese, hyperglycemic rats.
Current eye research 1998;17(11):1049-57.
1998: Yuka Okada; Shizuya Saika; Kumi Shirai; Natsuko Hashizume; Osamu Yamanaka; Yoshitaka Ohnishi; Emiko Senba
Immunolocalization of proto-oncogene products in keratocytes after epithelial ablation, alkali burn and penetrating injury of the cornea in rats.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1998;236(11):853-8.
1998: Shizuya Saika; Takeshi Miyamoto; Akio Yamanaka; Yoshiji Kawashima; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Shunsaku Ohmi; Yoshitaka Ohnishi; Akira Ooshima
Immunohistochemical evaluation of cellular deposits on posterior chamber intraocular lenses.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1998;236(10):758-65.
1998: Shizuya Saika; Takeshi Miyamoto; M Kimura; Shunsaku Ohmi; K Ohkawa; Yoshiji Kawashima; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Degenerated lens epithelial cells in rabbit and human eyes after intraocular lens implantation.
Journal of cataract and refractive surgery 1998;24(10):1396-8.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Immunohistochemical identification of proteoglycan types in fibrotic human capsules with intraocular lens implants.
Japanese journal of ophthalmology 1998;42(5):368-72.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Immunolocalization of hyaluronan and CD44 in quiescent and proliferating human lens epithelial cells.
Journal of cataract and refractive surgery 1998;24(9):1266-70.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Sai-ichi Tanaka; Yuka Okada; Osamu Yamanaka; T Katoh; Yoshitaka Ohnishi; Shunsaku Ohmi; Akira Ooshima; Akio Yamanaka
Immunolocalization of prolyl 4-hydroxylase in rabbit lens epithelial cells.
Journal of cataract and refractive surgery 1998;24(9):1261-5.
1998: Shizuya Saika; Osamu Yamanaka; Yoshiji Kawashima; Kiyomi Ohkawa; Yoshitaka Ohnishi; Akira Ooshima; M Kimura; Y Nakano; Winston W-Y Kao
OPC-15161 suppresses the proliferation of Tenon's capsule fibroblasts and the production of type I collagen and fibronectin stimulated by TGF-beta1 in vitro.
Current eye research 1998;17(9):933-40.
1998: Yoshiji Kawashima; Shizuya Saika; Osamu Yamanaka; Yuka Okada; Kiyomi Ohkawa; Yoshitaka Ohnishi
Immunolocalization of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human subconjunctival tissues.
Current eye research 1998;17(4):445-51.
1998: Shizuya Saika; Akio Yamanaka; A Yamanaka; A Minamide; K Kin; Kumi Shirai; Sai-ichi Tanaka; Yoshiji Kawashima; T Katoh; Yuka Okada; K Ohkawa; Yoshitaka Ohnishi
Subretinal administration of tissue-type plasminogen activator to speed the drainage of subretinal hemorrhage.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1998;236(3):196-201.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Shunsaku Ohmi; A Minamide; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Immunolocalization of prolyl 4-hydroxylase subunits, alpha-smooth muscle actin, and extracellular matrix components in human lens capsules with lens implants.
Experimental eye research 1998;66(3):283-94.
1998: Shizuya Saika; Yoshiji Kawashima; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Recombinant TIMP-1 and -2 enhance the proliferation of rabbit corneal epithelial cells in vitro and the spreading of rabbit corneal epithelium in situ.
Current eye research 1998;17(1):47-52.
1997: Shizuya Saika; Shunsaku Ohmi; Sai-ichi Tanaka; Takeshi Miyamoto; Yoshiji Kawashima; Yoshitaka Ohnishi; R Kanagawa; Akio Yamanaka; Akira Ooshima
Cell proliferation on the outer anterior capsule surface after extracapsular lens extraction in rabbits.
Journal of cataract and refractive surgery 1997;23(10):1528-31.
1997: Natsuko Hashizume; Shizuya Saika; A Ooshima; Osamu Yamanaka; Yuka Okada; Yoshitaka Ohnishi
Corneal epithelial basement membrane after experimental anterior stromal puncture in guinea pigs: immunohistochemical study.
Japanese journal of ophthalmology 1997;41(6):376-80.
1997: Shizuya Saika; Shunsaku Ohmi; Akira Ooshima; M Kimura; Sai-ichi Tanaka; Yuka Okada; Yoshitaka Ohnishi; Akio Yamanaka
Deposition of extracellular matrix on silicone intraocular lens implants in rabbits.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1997;235(8):517-22.
1997: Shizuya Saika; Shunsaku Ohmi; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akio Yamanaka; Akira Ooshima
Light and scanning electron microscopy of rabbit lens capsules with intraocular lenses.
Journal of cataract and refractive surgery 1997;23(5):787-94.
1997: Shizuya Saika; Sai-ichi Tanaka; Shunsaku Ohmi; A Minamide; Yoshitaka Ohnishi; Akio Yamanaka; Akira Ooshima; M Kimura
Deposition of extracellular matrix on intraocular lenses in rabbits: an immunohistochemical and transmission electron microscopic study.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1997;235(4):241-7.
1997: Shizuya Saika; Akira Ooshima; Osamu Yamanaka; M Kimura; Yuka Okada; O Tonoe; S Tanaka; Yoshitaka Ohnishi
In vitro effects of doxorubicin and mitomycin C on human Tenon's capsule fibroblasts.
Ophthalmic research 1997;29(2):91-102.
1997: Shizuya Saika; K Kin; Shunsaku Ohmi; Yoshitaka Ohnishi
Posterior capsule rupture by blunt ocular trauma.
Journal of cataract and refractive surgery 1997;23(1):139-40.
1996: Shizuya Saika; Shunsaku Ohmi; Akira Ooshima; M Kimura; K Ohkawa; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akio Yamanaka
Collagen synthesis in lens epithelial cells on capsules containing intraocular lens implants in rabbits: immunolocalization of prolyl 4-hydroxylase.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1996;234(12):755-60.
1996: Shizuya Saika; Shunsaku Ohmi; M Kimura; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akio Yamanaka; Akira Ooshima
[Electron microscopic observations on the posterior lens capsule after implantation of a silicone intraocular lens in rabbits].
Nippon Ganka Gakkai zasshi 1996;100(9):687-91.
1996: Yuka Okada; Shizuya Saika; Natsuko Hashizume; S Kobata; Osamu Yamanaka; Yoshitaka Ohnishi; E Senba
Expression of fos family and jun family proto-oncogenes during corneal epithelial wound healing.
Current eye research 1996;15(8):824-32.
1996: Shizuya Saika; Akira Ooshima; Osamu Yamanaka; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi
Effect of fibrostatin C, an inhibitor of prolyl 4-hydroxylase, on collagen secretion by human Tenon's capsule fibroblasts in vitro.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1996;234 Suppl 1():S214-22.
1996: Shunsaku Ohmi; C Takagishi; Natsuko Hashizume; Shizuya Saika
In-the-bag hyphema after intraocular lens implantation.
Journal of cataract and refractive surgery 1996;22(6):755-8.
1996: Shizuya Saika; Akira Ooshima; Osamu Yamanaka; O Tonoe; Yuka Okada; Yoshitaka Ohnishi; M Kimura
Immunolocalization of prolyl 4-hydroxylase in fibroblasts cultured from Tenon's capsule of humans.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1996;234(4):251-7.
1996: Shizuya Saika; Shunsaku Ohmi; R Kanagawa; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Lens epithelial cell outgrowth and matrix formation on intraocular lenses in rabbit eyes.
Journal of cataract and refractive surgery 1996;22 Suppl 1():835-40.
1996: Shizuya Saika; Akira Ooshima; K Shima; Sai-ichi Tanaka; Yoshitaka Ohnishi
Collagen types in healing alkali-burned corneal stroma in rabbits.
Japanese journal of ophthalmology 1996;40(3):303-9.
1996: Shizuya Saika; Osamu Yamanaka; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akira Ooshima
Pentoxifylline and pentifylline inhibit proliferation of human Tenon's capsule fibroblasts and production of type-I collagen and laminin in vitro.
Ophthalmic research 1996;28(3):165-70.
1995: Shizuya Saika; Akio Yamanaka; Sai-ichi Tanaka; Shunsaku Ohmi; Yoshitaka Ohnishi; Akira Ooshima
Extracellular matrix on intraocular lenses.
Experimental eye research 1995;61(6):713-21.
1995: Shizuya Saika; Akira Ooshima; Natsuko Hashizume; Osamu Yamanaka; Sai-ichi Tanaka; Yuka Okada; S Kobata
Effect of lysyl hydroxylase inhibitor, minoxidil, on ultrastructure and behavior of cultured rabbit subconjunctival fibroblasts.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1995;233(6):347-53.
1995: Shizuya Saika; Akira Ooshima; Osamu Yamanaka; Sai-ichi Tanaka; Yuka Okada; Natsuko Hashizume; Yoshitaka Ohnishi
Effect of a prolyl hydroxylase inhibitor on rabbit ocular fibroblasts.
Ophthalmic research 1995;27(6):335-46.
1995: Shizuya Saika; S Kobata; Natsuko Hashizume; Osamu Yamanaka; Yuka Okada; Akira Ooshima
Type IV collagen in the basement membrane of the corneal epithelium after alkali burns in guinea pigs.
Ophthalmic research 1995;27(3):129-35.
1994: Shizuya Saika; Natsuko Hashizume; Yuka Okada; S Kobata; Osamu Yamanaka; K Uenoyama; Akira Ooshima
Prolyl hydroxylase inhibitor and lysyl hydroxylase inhibitor inhibit spreading of corneal epithelium.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1994;232(8):499-502.
1993: Shizuya Saika; S Kobata; Osamu Yamanaka; Akio Yamanaka; K Okubo; T Oka; M Hosomi; Y Kano; Shunsaku Ohmi; S Uenoyama
Cellular fibronectin on intraocular lenses explanted from patients.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1993;231(12):718-21.
1993: Shizuya Saika; S Kobata; Natsuko Hashizume; Yuka Okada; Osamu Yamanaka
Epithelial basement membrane in alkali-burned corneas in rats. Immunohistochemical study.
Cornea 1993;12(5):383-90.
1993: Shizuya Saika
Ascorbic acid and proliferation of cultured rabbit keratocytes.
Cornea 1993;12(3):191-8.
1993: Shizuya Saika; K Uenoyama; K Hiroi; H Tanioka; K Takase; M Hikita
Ascorbic acid phosphate ester and wound healing in rabbit corneal alkali burns: epithelial basement membrane and stroma.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1993;231(4):221-7.
1993: Shizuya Saika; Osamu Yamanaka; Natsuko Hashizume; S Kobata; Yuka Okada; K Uenoyama; Akira Ooshima
Cis-hydroxyproline inhibits adhesion, migration and proliferation of cultured rabbit keratocytes.
Ophthalmic research 1993;25(6):363-70.
1992: A Nakai; Shizuya Saika
A case of frosted-branch retinal angiitis in a child.
Annals of ophthalmology 1992;24(11):415-7.
1992: Shizuya Saika
Ultrastructural effect of L-ascorbic acid 2-phosphate on cultured keratocytes.
Cornea 1992;11(5):439-45.
1992: Shizuya Saika; M Tamura; K Uenoyama; Akio Yamanaka; K Ohkubo; K Fukuda; H Iwane
Collagenous deposits on explanted intraocular lenses.
Journal of cataract and refractive surgery 1992;18(2):195-9.
1992: Shizuya Saika; K Uenoyama; K Hiroi; Akira Ooshima
L-ascorbic acid 2-phosphate enhances the production of type I and type III collagen peptides in cultured rabbit keratocytes.
Ophthalmic research 1992;24(2):68-72.
1992: Shizuya Saika; S Uenoyama; R Kanagawa; M Tamura; K Uenoyama
Phagocytosis and fibronectin of cells observed on intraocular lenses.
Japanese journal of ophthalmology 1992;36(2):184-91.
1991: Shizuya Saika; K Uenoyama; K Hiroi; Akira Ooshima
[Effect of L-ascorbic acid 2-phosphate on cultured rabbit keratocytes (the third report). The effect on production and secretion of type I collagen].
Nippon Ganka Gakkai zasshi 1991;95(9):835-40.
1991: Shizuya Saika; R Kanagawa; K Uenoyama; K Hiroi; J Hiraoka
[Effect of L-ascorbic acid 2-phosphate on cultured rabbit keratocytes (the second report)].
Nippon Ganka Gakkai zasshi 1991;95(1):39-44.
1991: Shizuya Saika; R Kanagawa; K Uenoyama; K Hiroi; J Hiraoka
L-ascorbic acid 2-phosphate, a phosphate derivative of L-ascorbic acid, enhances the growth of cultured rabbit keratocytes.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1991;229(1):79-83.
1991: Shizuya Saika; O Tonoe; R Kanagawa; K Uenoyama; Akio Yamanaka; K Fukuda; H Iwane
Immunohistochemical study of deposits on intraocular lenses explanted from human eyes.
Japanese journal of ophthalmology 1991;35(1):96-101.
1990: M Tamura; R Kanagawa; Shizuya Saika; Shunsaku Ohmi; T Nakao; C Kinoshita; K Uenoyama
Comparison of the cellular response on intraocular lenses implanted in rabbit eyes with and without extracapsular lens extraction.
Journal of cataract and refractive surgery 1990;16(6):746-50.
1990: K Uenoyama; M Tamura; C Kinoshita; R Kanagawa; Shunsaku Ohmi; T Nakao; Shizuya Saika
Experimental intraocular lens implantation in the rabbit eye and in the mouse peritoneal space. Part V: Phagocytosis and nuclear patterns of giant cells observed on the implanted lens surface.
Journal of cataract and refractive surgery 1990;16(4):465-70.
1990: R Kanagawa; Shizuya Saika; K Miyamoto; Shunsaku Ohmi; M Tamura; T Nakao
[Experimental study of cellular response on the intraocular lens surface in terms of the presence and distribution of fibronectin].
Nippon Ganka Gakkai zasshi 1990;94(6):549-52.
1990: R Kanagawa; Shizuya Saika; Shunsaku Ohmi; M Tamura; T Nakao
Presence and distribution of fibronectin on the surface of implanted intraocular lenses in rabbits.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1990;228(5):398-400.
1989: Shizuya Saika; M Tamura; T Nakao; R Kanagawa; K Uenoyama; J Hiraoka
[Experimental study of phagocytosis of the cells observed on the surface of intraocular lens].
Nippon Ganka Gakkai zasshi 1989;93(11):1068-74.