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Shigetoyo Saji

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Atsushi Suetsugu; Kimi Honma; Hisataka Moriwaki; Takahiro Ochiya; Shigetoyo Saji; Robert M Hoffman
Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models.
Atsushi Suetsugu; Ryan Thomas; Mark Truty; Michael Bouvet; Jason Fleming; Matthew Katz; Hisataka Moriwaki; Shigetoyo Saji; Robert M Hoffman
Non-invasive fluorescent-protein imaging of orthotopic pancreatic-cancer-patient tumorgraft progression in nude mice.
Atsushi Suetsugu; Ryan Thomas; Mark Truty; Michael Bouvet; Jason Fleming; Matthew Katz; Hisataka Moriwaki; Shigetoyo Saji; Robert M Hoffman
Multi-color palette of fluorescent proteins for imaging the tumor microenvironment of orthotopic tumorgraft mouse models of clinical pancreatic cancer specimens.

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2013: Atsushi Suetsugu; Kimi Honma; Hisataka Moriwaki; Takahiro Ochiya; Shigetoyo Saji; Robert M Hoffman
Imaging exosome transfer from breast cancer cells to stroma at metastatic sites in orthotopic nude-mouse models.
Advanced drug delivery reviews 2013;65(3):383-90.
2012: Atsushi Suetsugu; Ryan Thomas; Mark Truty; Michael Bouvet; Jason Fleming; Matthew Katz; Hisataka Moriwaki; Shigetoyo Saji; Robert M Hoffman
Non-invasive fluorescent-protein imaging of orthotopic pancreatic-cancer-patient tumorgraft progression in nude mice.
Anticancer research 2012;32(8):3063-7.
2012: Atsushi Suetsugu; Ryan Thomas; Mark Truty; Michael Bouvet; Jason Fleming; Matthew Katz; Hisataka Moriwaki; Shigetoyo Saji; Robert M Hoffman
Multi-color palette of fluorescent proteins for imaging the tumor microenvironment of orthotopic tumorgraft mouse models of clinical pancreatic cancer specimens.
Journal of cellular biochemistry 2012;113(7):2290-5.
2012: Atsushi Suetsugu; Ryan Thomas; Mark Truty; Michael Bouvet; Jason Fleming; Matthew Katz; Hisataka Moriwaki; Shigetoyo Saji; Robert M Hoffman
Imageable fluorescent metastasis resulting in transgenic GFP mice orthotopically implanted with human-patient primary pancreatic cancer specimens.
Anticancer research 2012;32(4):1175-80.
2011: Mohamed K Hassanein; Michael Bouvet; A R Moossa; Hisataka Moriwaki; Shigetoyo Saji; Atsushi Suetsugu; Robert M Hoffman
Stem-like and non-stem human pancreatic cancer cells distinguished by morphology and metastatic behavior.
Journal of cellular biochemistry 2011;112(12):3549-54.
2011: Yoshito Komatsu; Hisashi Oda; Yutaka Kimura; Masaki Kitajima; Junichi Sakamoto; Yuh Sakata; Jo Sakurai; Yusuke Tajima; Masahiro Takahashi; Yutaka Takahashi; Shigeyuki Tamura; Shigeru Tatebe; Takehiro Wakasugi; Shigetoyo Saji
Randomized phase II trial of first-line treatment with tailored irinotecan and S-1 therapy versus S-1 monotherapy for advanced or recurrent gastric carcinoma (JFMC31-0301).
Anti-cancer drugs 2011;22(6):576-83.
2011: Shigetoyo Saji; Takao Takahashi; Yoshihiro Kawaguchi; Shinji Osada; Kazuhiro Yoshida; Kazuya Yamaguchi
[The 9th international conference of the asian clinical oncology society in Japan after a twenty year interval--what is the standpoint of Japan in Asia ?].
Gan to kagaku ryoho. Cancer & chemotherapy 2011;38(6):885-91.
2011: Masakazu Toi; Shigehira Saji; Norikazu Masuda; Katsumasa Kuroi; Nobuaki Sato; Hiroyuki Takei; Yutaka Yamamoto; Shinji Ohno; Hiroko Yamashita; Kazufumi Hisamatsu; Kenjiro Aogi; Hiroji Iwata; Masahiro Takada; Takayuki Ueno; Shigetoyo Saji; Niramol Chanplakorn; Takashi Suzuki; Hironobu Sasano
Ki67 index changes, pathological response and clinical benefits in primary breast cancer patients treated with 24 weeks of aromatase inhibition.
Cancer science 2011;102(4):858-65.
2011: Atsushi Suetsugu; Yosuke Osawa; Masahito Nagaki; Shigetoyo Saji; Hisataka Moriwaki; Michael Bouvet; Robert M Hoffman
Imaging the recruitment of cancer-associated fibroblasts by liver-metastatic colon cancer.
Journal of cellular biochemistry 2011;112(3):949-53.
2011: Chikuma Hamada; Junichi Sakamoto; Taroh Satoh; Sotaro Sadahiro; Hideyuki Mishima; Kenichi Sugihara; Shigetoyo Saji; Naohiro Tomita
Does 1 year adjuvant chemotherapy with oral 5-FUs in colon cancer reduce the peak of recurrence in 1 year and provide long-term OS benefit?
Japanese journal of clinical oncology 2011;41(2):299-302.
2010: Atsushi Yamamoto; Yutaka Ozeki; Yoshihiro Ito; Ryosuke Horita; Shigetoyo Saji; Hiroshi Sugiyama; Kengo Matsunaga
[A case of well differentiated mucinous carcinoma of the gallbladder].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2010;107(11):1821-7.
2010: Atsushi Suetsugu; Yosuke Osawa; Masahito Nagaki; Hisataka Moriwaki; Shigetoyo Saji; Michael Bouvet; Robert M Hoffman
Simultaneous color-coded imaging to distinguish cancer "stem-like" and non-stem cells in the same tumor.
Journal of cellular biochemistry 2010;111(4):1035-41.
2010: Takuro Shimbo; Tsuguya Fukui; Chikashi Ishioka; Kohji Okamoto; Takahiro Okamoto; Shingo Kameoka; Atsushi Sato; Masakazu Toi; Kunihiko Matsui; Toshihiko Mayumi; Shigetoyo Saji; Masaru Miyazaki; Yuichi Takatsuka; Koichi Hirata
Quality of guideline development assessed by the Evaluation Committee of the Japan Society of Clinical Oncology.
International journal of clinical oncology 2010;15(3):227-33.
2010: Niramol Chanplakorn; Pongsthorn Chanplakorn; Takashi Suzuki; Katsuhiko Ono; Monica S M Chan; Yasuhiro Miki; Shigetoyo Saji; Takayuki Ueno; Masakazu Toi; Hironobu Sasano
Increased estrogen sulfatase (STS) and 17beta-hydroxysteroid dehydrogenase type 1(17beta-HSD1) following neoadjuvant aromatase inhibitor therapy in breast cancer patients.
Breast cancer research and treatment 2010;120(3):639-48.
2010: Bunzo Nakata; Akihito Tsuji; Yasushi Mitachi; Naoyuki Taenaka; Toshiki Kamano; Keisuke Oikawa; Naoyoshi Onoda; Mariko Kambe; Masahiro Takahashi; Tetsuhiko Shirasaka; Satoshi Morita; Junichi Sakamoto; Yukari Tanaka; Shigetoyo Saji; Kosei Hirakawa
Phase II trial of S-1 plus low-dose cisplatin for unresectable and recurrent gastric cancer (JFMC27-9902 Step2).
Oncology 2010;79(5-6):337-42.
2009: Shinji Osada; Kazuhiro Yoshida; Shigetoyo Saji
A novel strategy by cryoablation for advanced hepatoma.
Anticancer research 2009;29(12):5203-9.
2008: Reiko Suzuki; Tove Rylander-Rudqvist; Shigetoyo Saji; Leif Bergkvist; Herman Adlercreutz; Alicja Wolk
Dietary lignans and postmenopausal breast cancer risk by oestrogen receptor status: a prospective cohort study of Swedish women.
British journal of cancer 2008;98(3):636-40.
2008: Reiko Suzuki; Tove Rylander-Rudqvist; Weimin Ye; Shigetoyo Saji; Herman Adlercreutz; Alicja Wolk
Dietary fiber intake and risk of postmenopausal breast cancer defined by estrogen and progesterone receptor status--a prospective cohort study among Swedish women.
International journal of cancer. Journal international du cancer 2008;122(2):403-12.
2007: Satoshi Morita; Bunzo Nakata; Akihito Tsuji; Yasushi Mitachi; Tetsuhiko Shirasaka; Shigetoyo Saji; Yasuo Ohashi; Junichi Sakamoto; Kosei Hirakawa
A phase I study of combination therapy of the oral fluorinated pyrimidine compound S-1 with low-dose cisplatin twice-a-week administration (JFMC27-9902 Step2) in patients with advanced gastric cancer using a continual reassessment method.
Japanese journal of clinical oncology 2007;37(12):924-9.
2007: Dai Kitagawa; Shigetoyo Saji
[The differences of standard therapy for breast cancer between Europe/America and Japan--chemotherapy, operation,and radiotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2007;34(5):690-3.
2007: Junichi Sakamoto; Chikuma Hamada; S Yoshida; S Kodaira; M Yasutomi; T Kato; K Oba; H Nakazato; Shigetoyo Saji; Yasuo Ohashi
An individual patient data meta-analysis of adjuvant therapy with uracil-tegafur (UFT) in patients with curatively resected rectal cancer.
British journal of cancer 2007;96(8):1170-7.
2007: Eiji Suzuki; Rinpei Niwa; Shigetoyo Saji; Mariko Muta; Makiko Hirose; Shigeru Iida; Yukimasa Shiotsu; Mitsuo Satoh; Kenya Shitara; Masahide Kondo; Masakazu Toi
A nonfucosylated anti-HER2 antibody augments antibody-dependent cellular cytotoxicity in breast cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(6):1875-82.
2007: Yoshimasa Mizuno; Yasuhiro Sumi; Sho Nachi; Yoshihiro Ito; Tsutomu Marui; Shigetoyo Saji; Hirokazu Matsutomo
Acinar cell carcinoma arising from an ectopic pancreas.
Surgery today 2007;37(8):704-7.
2006: Y Mizuno; Y Sumi; Sho Nachi; Y Ito; T Marui; Shigetoyo Saji; H Matsutomo
A case of a large retroperitoneal liposarcoma presenting as an incarcerated inguinal hernia.
Hernia : the journal of hernias and abdominal wall surgery 2006;10(5):439-42.
2006: Reiko Suzuki; Tove Rylander-Rudqvist; Weimin Ye; Shigetoyo Saji; Alicja Wolk
Body weight and postmenopausal breast cancer risk defined by estrogen and progesterone receptor status among Swedish women: A prospective cohort study.
International journal of cancer. Journal international du cancer 2006;119(7):1683-9.
2006: Hiroyuki Tomita; Yukihiro Takagi; Shigetoyo Saji; Atushi Kimura; Hisashi Imai; Yasuhiko Sumi
Self-inflicted splenic injury in snowboarders: postural analysis of forward falls of 10 consecutive patients.
The American journal of emergency medicine 2006;24(3):308-12.
2006: Tomoyoshi Suzuki; Masakazu Toi; Shigetoyo Saji; Kazumi Horiguchi; Tomoyuki Aruga; Eiji Suzuki; Shinichiro Horiguchi; Nobuaki Funata; Katsuyuki Karasawa; Noriko Kamata
Early breast cancer.
International journal of clinical oncology 2006;11(2):108-19.
2005: Reiko Suzuki; Weimin Ye; Tove Rylander-Rudqvist; Shigetoyo Saji; GRaham Colditz; Alicja Wolk
Alcohol and postmenopausal breast cancer risk defined by estrogen and progesterone receptor status: a prospective cohort study.
Journal of the National Cancer Institute 2005;97(21):1601-8.
2005: Shigetoyo Saji; Makiko Hirose; Masakazu Toi
Clinical significance of estrogen receptor beta in breast cancer.
Cancer chemotherapy and pharmacology 2005;56 Suppl 1():21-6.
2005: Masakazu Toi; Kazumi Horiguchi; Hiroko Bando; Shigetoyo Saji; Louis W C Chow
Trastuzumab: updates and future issues.
Cancer chemotherapy and pharmacology 2005;56 Suppl 1():94-9.
2005: Nobuhisa Matsuhashi; Masanao Saio; Atsushi Matsuo; Yasuyuki Sugiyama; Shigetoyo Saji
The evaluation of gastric cancer sensitivity to 5-FU/CDDP in terms of induction of apoptosis: time- and p53 expression-dependency of anti-cancer drugs.
Oncology reports 2005;14(3):609-15.
2005: Shigetoyo Saji; Masayo Kawakami; Shin-Ichi Hayashi; Nobuyuki Yoshida; Makiko Hirose; Shin-Ichiro Horiguchi; Akihiro Itoh; Nobuaki Funata; Stuart L Schreiber; Minoru Yoshida; Masakazu Toi
Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer.
Oncogene 2005;24(28):4531-9.
2005: Satoshi Suzuki; Mitsuo Kusano; Kiyoshi Inokuchi; Shigetoyo Saji; Tetsuo Takeuchi
[Problems of case accumulation in a clinical trial of hepatic arterial infusion after resection of hepatic metastases: A summary of the study design and questionnaire survey of the participating centers in study no. 29-0003 of the Japanese Foundation for Multidisciplinary Treatment of Cancer (JFMC)].
Gan to kagaku ryoho. Cancer & chemotherapy 2005;32(6):789-94.
2005: Nobuhisa Matsuhashi; Masanao Saio; Atsushi Matsuo; Yasuyuki Sugiyama; Shigetoyo Saji
Apoptosis induced by 5-fluorouracil, cisplatin and paclitaxel are associated with p53 gene status in gastric cancer cell lines.
International journal of oncology 2005;26(6):1563-7.
2004: Yutaka Takahashi; Tetsuo Takeuchi; Jyunichi Sakamoto; Masayoshi Mai; Masaki Kitajima; Tetsuro Kubota; Tetsuya Toge; Shigetoyo Saji
[A randomized phase II clinical trial of tailored CPT-11 + TS-1 vs TS-1 in patients with advanced or recurrent gastric carcinoma as the first-line chemotherapy (JFMC31-0301)].
Gan to kagaku ryoho. Cancer & chemotherapy 2004;31(12):1969-72.
2004: Shinji Osada; Shigetoyo Saji
The clinical significance of monitoring alkaline phosphatase level to estimate postoperative liver failure after hepatectomy.
Hepato-gastroenterology 2004;51(59):1434-8.
2004: Masahiro Takada; Akemi Kataoka; Masakazu Toi; Hiroko Bando; Kazumi Toyama; Shinichiro Horiguchi; Takayuki Ueno; Stig Linder; Shigetoyo Saji; Yukiko Hayashi; Nobuaki Funata; Junko Kinoshita; Sigeru Murakami; Shinji Ohono
A close association between alteration in growth kinetics by neoadjuvant chemotherapy and survival outcome in primary breast cancer.
International journal of oncology 2004;25(2):397-405.
2004: Nobuhisa Matsuhashi; Masanao Saio; Atsushi Matsuo; Yasuyuki Sugiyama; Shigetoyo Saji
p53 dependence and apoptosis in response to FP treatment with p53-transfected colon cancer cell lines by use of thin layer collagen gel.
Oncology reports 2004;12(2):357-61.
2004: Gaku Matsumoto; Mohammad Atiqur Rahman; Mariko Muta; Tadahiko Nakamura; Hiroko Bando; Shigetoyo Saji; Koji Tsuruta; Atsutake Okamoto; Masakazu Toi
DFU, a selective COX-2 inhibitor, suppresses MCF-7 xenograft tumor growth in mice.
Oncology reports 2004;12(2):281-5.
2004: Hiroyasu Yamashiro; Kazumi Toyama; Hiroko Bando; Shigetoyo Saji; Masakazu Toi
[Trastuzumab treatment for breast cancer].
Nihon rinsho. Japanese journal of clinical medicine 2004;62(7):1305-11.
2004: Masakazu Toi; Hiroko Bando; Shinichiro Horiguchi; Masahiro Takada; A Kataoka; Takayuki Ueno; Shigetoyo Saji; Mariko Muta; Nobuaki Funata; S Ohno
Modulation of thymidine phosphorylase by neoadjuvant chemotherapy in primary breast cancer.
British journal of cancer 2004;90(12):2338-43.
2004: Yutaka Takahashi; Junichi Sakamoto; Tetsuo Takeuchi; Masayoshi Mai; Tetsuro Kubota; Masaki Kitajima; Yusuke Tanigawara; Yoshito Komatsu; Tetsuya Toge; Shigetoyo Saji
A randomized phase II clinical trial of tailored CPT-11 + S-1 vs S-1 in patients with advanced or recurrent gastric carcinoma as the first line chemotherapy.
Japanese journal of clinical oncology 2004;34(6):342-5.
2004: Nobuyuki Yoshida; Yoko Omoto; Akio Inoue; Hidetaka Eguchi; Yasuhito Kobayashi; Masafumi Kurosumi; Shigetoyo Saji; Kimito Suemasu; Tomoki Okazaki; Kei Nakachi; Toshiro Fujita; Shin-ichi Hayashi
Prediction of prognosis of estrogen receptor-positive breast cancer with combination of selected estrogen-regulated genes.
Cancer science 2004;95(6):496-502.
2004: Nobuhisa Matsuhashi; Masanao Saio; Atsushi Matsuo; Yasuyuki Sugiyama; Shigetoyo Saji
Expression of p53 protein as a predictor of the response to 5-fluorouracil and cisplatin chemotherapy in human gastrointestinal cancer cell lines evaluated with apoptosis by use of thin layer collagen gel.
International journal of oncology 2004;24(4):807-13.
2004: Shinji Osada; Shigetoyo Saji; Takao Takahashi
A case report of papilla Vater carcinoma showing positive expression of thymidine phosphorylase.
Hepato-gastroenterology 2004;51(56):375-7.
2004: Satoshi Morita; Yasuo Ohashi; Kosei Hirakawa; Bunzo Nakata; Shigetoyo Saji; Junichi Sakamoto
Phase I/II study of combination therapy of oral fluorinated pyrimidine compound S-1 with low-dose cisplatin in patients with unresectable and/or recurrent advanced gastric cancer: a novel study design to evaluate safety and efficacy.
Japanese journal of clinical oncology 2004;34(3):159-61.
2004: Katsuki Ito; Hiroaki Nakazato; Akihiko Koike; Hiroshi Takagi; Shigetoyo Saji; Shozo Baba; Masayoshi Mai; Jun-ichi Sakamoto; Yasuo Ohashi
Long-term effect of 5-fluorouracil enhanced by intermittent administration of polysaccharide K after curative resection of colon cancer. A randomized controlled trial for 7-year follow-up.
International journal of colorectal disease 2004;19(2):157-64.
2004: Masayo Kawakami; Shigetoyo Saji; Masakazu Toi
[Controversies in endocrine therapy for breast cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2004;31(2):181-7.
2004: Chikashi Nakanishi; Tatsuro Yamaguchi; Takeru Iijima; Shigetoyo Saji; Masakazu Toi; Takeo Mori; Michiko Miyaki
Germline mutation of the LKB1/STK11 gene with loss of the normal allele in an aggressive breast cancer of Peutz-Jeghers syndrome.
Oncology 2004;67(5-6):476-9.
2004: Shigetoyo Saji; Makiko Hirose; Masakazu Toi
Novel sensitizing agents: potential contribution of COX-2 inhibitor for endocrine therapy of breast cancer.
Breast cancer (Tokyo, Japan) 2004;11(2):129-33.
2004: Masakazu Toi; Masahiro Takada; Hiroko Bando; Kazumi Toyama; Hiroyasu Yamashiro; Shinichiro Horiguchi; Shigetoyo Saji
Current status of antibody therapy for breast cancer.
Breast cancer (Tokyo, Japan) 2004;11(1):10-4.
2004: Katsuyuki Kunieda; Yoshihiro Tanaka; Narutoshi Nagao; Kazuya Yamaguchi; Jun Sano; Shinji Osada; Shigetoyo Saji; Kuniyasu Shimokawa
Large solitary fibrous tumor of the retroperitoneum: report of a case.
Surgery today 2004;34(1):90-3.
2004: Shinji Osada; Shigetoyo Saji; Toshiya Kuno
Clinical significance of combination study of apoptotic factors and proliferating cell nuclear antigen in estimating the prognosis of hepatocellular carcinoma.
Journal of surgical oncology 2004;85(1):48-54.
2003: Nobuhisa Matsuhashi; Atsushi Matsuo; Yoshihiro Kawaguchi; Yasuyuki Sugiyama; Shigetoyo Saji
[Relation between p53 expression of human colon cancer cell lines and induction of apoptosis by anticancer drugs].
Gan to kagaku ryoho. Cancer & chemotherapy 2003;30(11):1855-8.
2003: Koji Matsui; Nozomi Amaoka; Shinji Osada; Narutoshi Nagao; Kazuya Yamaguchi; Jun Sano; Yoshihiro Kawaguchi; Hiroshi Takao; Yasuyuki Sugiyama; Shigetoyo Saji
[Percutaneous cryoablation therapy under local anesthesia for unresectable metastatic liver tumors].
Gan to kagaku ryoho. Cancer & chemotherapy 2003;30(11):1591-4.
2003: Yoshihiro Kawaguchi; Yasuyuki Sugiyama; Shigetoyo Saji
[Cryoimmunological therapy with local injection of OK-432 against advance or recurrent breast cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2003;30(11):1583-6.
2003: Katsumasa Kuroi; Hiroko Bando; Shigetoyo Saji; Masakazu Toi
Protracted administration of weekly docetaxel in metastatic breast cancer.
Oncology reports 2003;10(5):1479-84.
2003: Mariko Muta; Gaku Matsumoto; Kiyoshi Hiruma; Shigetoyo Saji; Emi Nakashima; Masakazu Toi
Impact of vasculogenesis on solid tumor growth in a rat model.
Oncology reports 2003;10(5):1213-8.
2003: Junichi Sakamoto; Hiroshi Hamashima; Harumi Suzuki; Katsuki Ito; Masayoshi Mai; Shigetoyo Saji; Masakazu Fukushima; Yasuyuki Matsushita; Hiroaki Nakazato
Thymidylate synthase expression as a predictor of the prognosis of curatively resected colon carcinoma in patients registered in an adjuvant immunochemotherapy clinical trial.
Oncology reports 2003;10(5):1081-90.
2003: Yutaka Yamamoto; Jun-ichi Yamashita; Masakazu Toi; Mariko Muta; Shigenori Nagai; Nobuo Hanai; Akiko Furuya; Yoshio Osawa; Shigetoyo Saji; Michio Ogawa
Immunohistochemical analysis of estrone sulfatase and aromatase in human breast cancer tissues.
Oncology reports 2003;10(4):791-6.
2003: Masato Urano; Chihiro Tanaka; Yasuyuki Sugiyama; Kiichi Miya; Shigetoyo Saji
Antitumor effects of residual tumor after cryoablation: the combined effect of residual tumor and a protein-bound polysaccharide on multiple liver metastases in a murine model.
Cryobiology 2003;46(3):238-45.
2003: Masakazu Toi; Hiroko Bando; Shigetoyo Saji
Decision tree and paradigms of primary breast cancer: changes elicited by preoperative therapy.
Medical science monitor : international medical journal of experimental and clinical research 2003;9(5):RA90-5.
2003: Shinji Osada; Shigetoyo Saji
New approach to cancer therapy: the application of signal transduction to anti-cancer drug.
Current medicinal chemistry. Anti-cancer agents 2003;3(2):119-31.
2003: Hisashi Saji; Masakazu Toi; Shigetoyo Saji; Morio Koike; Kimitoshi Kohno; Michihiko Kuwano
Nuclear expression of YB-1 protein correlates with P-glycoprotein expression in human breast carcinoma.
Cancer letters 2003;190(2):191-7.
2003: Takao Takahashi; Bun Sano; Takayasu Nagata; Hiroki Kato; Yasuyuki Sugiyama; Katsuyuki Kunieda; Masashi Kimura; Yukio Okano; Shigetoyo Saji
Polo-like kinase 1 (PLK1) is overexpressed in primary colorectal cancers.
Cancer science 2003;94(2):148-52.
2003: Margaret Warner; Ling Wang; Weihua Zhang; Guojun Cheng; Hideki Sakaguchi; Shigetoyo Saji; Stefan Nilsson; Thomas Kiesselbach; Jan-�ke GUSTAFSSON
Analysis of estrogen receptor expression in tissues.
Methods in enzymology 2003;364():448-63.
2003: Takami Fukui; Kouji Matsui; Hiroki Kato; Hiroshi Takao; Yasuyuki Sugiyama; Katsuyuki Kunieda; Shigetoyo Saji
Significance of apoptosis induced by tumor necrosis factor-alpha and/or interferon-gamma against human gastric cancer cell lines and the role of the p53 gene.
Surgery today 2003;33(11):847-53.
2003: Noriaki Kojima; Katsuyuki Kunieda; Koji Matsui; Hiroki Kato; Shigetoyo Saji
Evaluation of carcinoembryonic antigen mRNA in living, necrotic, and apoptotic gastric cancer cells by reverse transcriptase-polymerase chain reaction.
Surgery today 2003;33(11):839-46.
2003: Shigeru Mori; Katsuyuki Kunieda; Yasuyuki Sugiyama; Shigetoyo Saji
Prediction of 5-fluorouracil and cisplatin synergism for advanced gastrointestinal cancers using a collagen gel droplet embedded culture.
Surgery today 2003;33(8):577-83.
2003: Katsumasa Kuroi; Hiroko Bando; Shigetoyo Saji; Masakazu Toi
Weekly schedule of docetaxel in breast cancer: evaluation of response and toxicity.
Breast cancer (Tokyo, Japan) 2003;10(1):10-4.
2002: S Aoki; Y Takagi; M Hayakawa; K Yamaguchi; M Futamura; Katsuyuki Kunieda; Shigetoyo Saji
Detection of peritoneal micrometastases by reverse transcriptase-polymerase chain reaction targeting carcinoembryonic antigen and cytokeratin 20 in colon cancer patients.
Journal of experimental & clinical cancer research : CR 2002;21(4):555-62.
2002: Shigetoyo Saji; Tetsuya Toge; Yasuhiko Kurosu; Koichi Hirata; Akira Gochi; Suketami Tominaga; Kiyoshi Inokuchi
[Interim report of JFMC study no. 23--phase III randomized clinical trial on the effectiveness of low-dose cisplatin plus 5-FU as a postoperative adjuvant chemotherapy for advanced gastric cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2002;29(13):2499-507.
2002: Chikashi Nakanishi; Masakazu Toi; Shigetoyo Saji; Hiroko Bando
[Current indications for mastectomy in patients with breast cancer].
Nihon Geka Gakkai zasshi 2002;103(11):821-4.
2002: Shigetoyo Saji; Masakazu Toi
Aromatase inhibitors and other novel agents in breast cancer treatment.
Expert opinion on emerging drugs 2002;7(2):303-19.
2002: Shigetoyo Saji; Yoko Omoto; Chikako Shimizu; Margaret Warner; Yukiko Hayashi; Shin-ichiro Horiguchi; Toru Watanabe; Shin-ichi Hayashi; Jan-�ke GUSTAFSSON; Masakazu Toi
Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor.
Cancer research 2002;62(17):4849-53.
2002: Naoki Okumura; Shigetoyo Saji; Hidetaka Eguchi; Shin-ichi Hayashi; Shigetoyo Saji; Shigeru Nakashima
Estradiol stabilizes p53 protein in breast cancer cell line, MCF-7.
Japanese journal of cancer research : Gann 2002;93(8):867-73.
2002: Weihua Zhang; Jenny Ekman; Asa Almkvist; Shigetoyo Saji; Ling Wang; Margaret Warner; Jan-�ke GUSTAFSSON
Involvement of androgen receptor in 17beta-estradiol-induced cell proliferation in rat uterus.
Biology of reproduction 2002;67(2):616-23.
2002: Naoki Okumura; Shigehira Saji; Hidetaka Eguchi; Shigeru Nakashima; Shigetoyo Saji; Shin-Ichi Hayashi
Distinct promoter usage of mdm2 gene in human breast cancer.
Oncology reports 2002;9(3):557-63.
2002: Toshiya Kuno; Yasuhiro Yamada; Yoshinobu Hirose; Masaki Katayama; Keiko Sakata; Akira Hara; Shigetoyo Saji; Hideki Mori
Induction of apoptosis by sulindac in azoxymethane-induced possible colonic premalignant lesions in rats.
Japanese journal of cancer research : Gann 2002;93(3):242-6.
2002: Carlo Palmieri; G J Cheng; Shigetoyo Saji; M Zelada-Hedman; A Wärri; Weihua Zhang; Susan Van Noorden; T Wahlstrom; R Charles Coombes; Margaret Warner; Jan-�ke GUSTAFSSON
Estrogen receptor beta in breast cancer.
Endocrine-related cancer 2002;9(1):1-13.
2002: Shigetoyo Saji; Yoko Omoto; Chikako Shimizu; Shin-ichiro Horiguchi; Toru Watanabe; Nobuaki Funata; Shin-ichi Hayash; Jan-�ke GUSTAFSSON; Masakazu Toi
Clinical impact of assay of estrogen receptor beta cx in breast cancer.
Breast cancer (Tokyo, Japan) 2002;9(4):303-7.
2002: Katsuyuki Kunieda; Shigetoyo Saji; Yasuyuki Sugiyama; Shinji Osada; Jun Sano; Narutoshi Nagao; Takao Takahashi; Yukihiro Takagi; Yasuaki Arai
Evaluation of treatment for synchronous hepatic metastases from gastric cancer with special reference to long-term survivors.
Surgery today 2002;32(7):587-93.
2002: Bun Sano; Yasuyuki Sugiyama; Katsuyuki Kunieda; Jun Sano; Shigetoyo Saji
Antitumor effects induced by the combination of TNP-470 as an angiogenesis inhibitor and lentinan as a biological response modifier in a rabbit spontaneous liver metastasis model.
Surgery today 2002;32(6):503-9.
2002: Katsumasa Kuroi; Chikako Tanaka; Hiroko Bando; Shigetoyo Saji; Kazuo Hayashi; Masakazu Toi
[Efficacy of biweekly paclitaxel therapy in advanced or recurrent breast cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2002;29(1):55-60.
2002: Guojun Cheng; Weihua Zhang; Sirpa Mäkinen; Sari Mäkelä; Shigetoyo Saji; Margaret Warner; Jan-�ke GUSTAFSSON; Outi Hovatta
A role for the androgen receptor in follicular atresia of estrogen receptor beta knockout mouse ovary.
Biology of reproduction 2002;66(1):77-84.
2002: Yukihiro Takagi; Shinichirou Mizui; Shigeru Mori; Daizou Fukada; Shigetoyo Saji; Masayuki Kanematsu
Ureteric band obstruction of the small intestine after radical gynecologic surgery.
Journal of clinical gastroenterology 2002;34(1):105-6.
2002: Yukihiro Takagi; Masahiro Katada; Shigeru Mori; Shigetoyo Saji; Kuniyasu Shimokawa; Takeshi Yosikawa; Hisataka Moriwaki
Leiomyosarcoma of the small intestine presenting with bacterial overgrowth syndrome.
Journal of clinical gastroenterology 2002;34(1):104-5.
2001: EV Jensen; Guojun Cheng; C Palmieri; Shigetoyo Saji; Sari Mäkelä; Susan Van Noorden; T Wahlström; Margaret Warner; R Charles Coombes; Jan-�ke GUSTAFSSON
Estrogen receptors and proliferation markers in primary and recurrent breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15197-202.
2001: Naoe Goto; Ichiro Yasuda; Toshihiko Uematsu; Nobuhiro Kanemura; S Takao; K Ando; Tomohiro Kato; Shinji Osada; H Takao; Shigetoyo Saji; Kuniyasu Shimokawa; Hisataka Moriwaki
Intrahepatic cholangiocarcinoma arising 10 years after the excision of congenital extrahepatic biliary dilation.
Journal of gastroenterology 2001;36(12):856-62.
2001: S Takai; Yoshimune Shiratori; Masayuki Kanematsu; K Yamazaki; Takafumi Naiki; Ichiro Yasuda; Masahito Nagaki; Nobuo Murakami; Tomohiro Kato; H Takao; Kuniyasu Shimokawa; Hiroaki Hoshi; Shigetoyo Saji; Hisataka Moriwaki
Usefulness of MR imaging in the postsurgical monitoring of gallbladder cancer in a patient with bile duct cancer that developed 7 years after resection of mucinous adenocarcinoma of the gallbladder.
Journal of gastroenterology 2001;36(11):787-9.
2001: Yasuyuki Sugiyama; Shigetoyo Saji; Kiichi Miya; Katsuyuki Kunieda; Hiroshi Takao; Yoshihiro Kawaguchi; A Kimura; S Honda; Koji Matsui
[Therapeutic effect of multimodal therapy, such as cryosurgery, locoregional immunotherapy and systemic chemotherapy against far advanced breast cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2001;28(11):1616-9.
2001: H Saji; M Koike; T Yamori; Shigetoyo Saji; Motoharu Seiki; K Matsushima; M Toi
Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma.
Cancer 2001;92(5):1085-91.
2001: Atsushi Matsuo; A Watanabe; T Takahashi; M Futamura; S Mori; Yasuyuki Sugiyama; Yoshito Takahashi; Shigetoyo Saji
A simple method for classification of cell death by use of thin layer collagen gel for the detection of apoptosis and/or necrosis after cancer chemotherapy.
Japanese journal of cancer research : Gann 2001;92(7):813-9.
2001: Shigetoyo Saji; Hideki Sakaguchi; Sandra Andersson; Margaret Warner; J Gustafsson
Quantitative analysis of estrogen receptor proteins in rat mammary gland.
Endocrinology 2001;142(7):3177-86.
2001: Katsuyuki Kunieda; K Yamaguchi; Shigetoyo Saji
[Significance of detection of micrometastases in regional lymph nodes in cancer patients using RT-PCR].
Nihon Geka Gakkai zasshi 2001;102(6):449-52.
2001: Weihua Zhang; S Makela; L C Andersson; SM Salmi; Shigetoyo Saji; Jeanette Webster Marketon; EV Jensen; Stefan Nilsson; Margaret Warner; Jan-�ke GUSTAFSSON
A role for estrogen receptor beta in the regulation of growth of the ventral prostate.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6330-5.
2001: Shigetoyo Saji; Katsuyuki Kunieda; Yasuyuki Sugiyama
[Immunochemotherapy for cancer patients of the stomach--cancer therapy keeping with good host-immunocompetency].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 4():420-6.
2001: Shinji Osada; Shigetoyo Saji; K Osada
Critical role of extracellular signal-regulated kinase phosphorylation on menadione (vitamin K3) induced growth inhibition.
Cancer 2001;91(6):1156-65.
2001: A Watanabe; Katsuyuki Kunieda; Shigetoyo Saji
A ruptured pancreaticoduodenal artery aneurysm associated with a splenic artery aneurysm: report of a case.
Surgery today 2001;31(6):542-5.
2000: T Takahashi; M Futamura; Naoki Yoshimi; J Sano; M Katada; Y Takagi; M Kimura; Takashi Yoshioka; Yukio Okano; Shigetoyo Saji
Centrosomal kinases, HsAIRK1 and HsAIRK3, are overexpressed in primary colorectal cancers.
Japanese journal of cancer research : Gann 2000;91(10):1007-14.
2000: Y Takagi; M Futamura; K Yamaguchi; S Aoki; T Takahashi; Shigetoyo Saji
Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers.
Gut 2000;47(2):268-71.
2000: K Yamaguchi; Y Takagi; S Aoki; M Futamura; Shigetoyo Saji
Significant detection of circulating cancer cells in the blood by reverse transcriptase-polymerase chain reaction during colorectal cancer resection.
Annals of surgery 2000;232(1):58-65.
2000: Weihua Zhang; Shigetoyo Saji; Sirpa Mäkinen; Guojun Cheng; EV Jensen; Margaret Warner; Jan-�ke GUSTAFSSON
Estrogen receptor (ER) beta, a modulator of ERalpha in the uterus.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):5936-41.
2000: Tetsuya Toge; H Nakazato; Masahiko Nishiyama; Koichi Hirata; Susumu Yamamitsu; M Sowa; Shigetoyo Saji
[Current status of "low-dose cisplatin-5-FU therapy" for solid tumors (2nd report)--from a nationwide questionnaire on its adverse effects].
Gan to kagaku ryoho. Cancer & chemotherapy 2000;27(4):549-58.
2000: Shigetoyo Saji; EV Jensen; Stefan Nilsson; T Rylander; Margaret Warner; Jan-�ke GUSTAFSSON
Estrogen receptors alpha and beta in the rodent mammary gland.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):337-42.
2000: Jun Sano; Yasuyuki Sugiyama; Katsuyuki Kunieda; Bun Sano; Shigetoyo Saji
Therapeutic effect of TNP-470 on spontaneous liver metastasis of colon tumors in the rabbit.
Surgery today 2000;30(12):1100-6.
2000: A Watanabe; Shigeru Nakashima; T Adachi; Shigetoyo Saji; Yoshinori Nozawa
Changes in the expression of lipid-mediated signal-transducing enzymes in the rat liver after partial hepatectomy.
Surgery today 2000;30(7):622-30.
2000: Katsuyuki Kunieda; Shigetoyo Saji; I Kuwabara; A Watanabe; M Katoh; Yasuyuki Sugiyama; Kuniyasu Shimokawa
Rapid growth of a retroperitoneal rhabdomyosarcoma following right hemicolectomy for ascending colon cancer: report of a case.
Surgery today 2000;30(4):372-5.
2000: Katsuyuki Kunieda; Shigetoyo Saji; S Mori; M Katoh; Kiichi Miya; Keigo Yasuda; Tomoatsu Mune; Kuniyasu Shimokawa
Recurrence of giant adrenocortical carcinoma in the contralateral adrenal gland 6 years after surgery: report of a case.
Surgery today 2000;30(3):294-7.
2000: Masayasu Kato; Shigetoyo Saji; Masayuki Kanematsu; D Fukada; Kiichi Miya; T Umemoto; Katsuyuki Kunieda; Yasuyuki Sugiyama; Hiroshi Takao; Yoshihiro Kawaguchi; Yukihiro Takagi; Hiroshi Kondo; Hiroaki Hoshi
Detection of lymph-node metastases in patients with gastric carcinoma: comparison of three MR imaging pulse sequences.
Abdominal imaging 2000;25(1):25-9.
1999: Yasuyuki Sugiyama; Shigetoyo Saji
[Tissue polypeptide antigen (TPA)].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():529-31.
1999: M Kato; Shigetoyo Saji; Y Kawaguchi; Katsuyuki Kunieda; Yasuyuki Sugiyama; Y Takagi; T Hiraoka; I Kumazawa; T Adachi
A comparison of the prognostic significance between the number of metastatic lymph nodes and nodal stage in gastric carcinoma.
Hepato-gastroenterology 1999;46(30):3281-6.
1999: Narutoshi Nagao; M Katoh; I Kumazawa; H Tomita; Yasuyuki Sugiyama; Katsuyuki Kunieda; Kiichi Miya; Shigetoyo Saji
[A recurrent case of esophageal cancer in which metastatic skin tumor disappeared after local injection of activated lymphocytes with tumor-pulsed dendritic cells].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26(12):1937-9.
1999: Kiichi Miya; Shigetoyo Saji; D Fukada; T Umemoto; Katsuyuki Kunieda; Yasuyuki Sugiyama; Hiroshi Takao; Masayasu Kato; Yoshihiro Kawaguchi
[Clinical evaluation of intermittent hepatic arterial infusion therapy with CDDP and 5-FU for liver metastasis of colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26(12):1715-7.
1999: Shigetoyo Saji; Yasuyuki Sugiyama; Katsuyuki Kunieda; T Umemoto
[Recent progress in biological therapies for cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1999;26 Suppl 1():32-41.
1999: Shigetoyo Saji; Shigeru Nakashima; S Hayashi; M Toi; S Saji; Y Nozawa
Overexpression of MDM2 in MCF-7 promotes both growth advantage and p53 accumulation in response to estradiol.
Japanese journal of cancer research : Gann 1999;90(2):210-8.
1999: Katsuyuki Kunieda; Shigetoyo Saji; Y Tanaka; M Katoh; D Fukada; Kuniyasu Shimokawa
An abdominal desmoid tumor involving the xyphoid and costal chondrium associated with pregnancy: report of a case.
Surgery today 1999;29(9):927-30.
1999: T Adachi; Yasuyuki Sugiyama; Shigetoyo Saji
Solitary fibrous benign mesothelioma of the peritoneum: report of a case.
Surgery today 1999;29(9):915-8.
1999: Shigetoyo Saji; J Sakamoto; S Teramukai; Katsuyuki Kunieda; Yasuyuki Sugiyama; Y Ohashi; H Nakazato
Impact of splenectomy and immunochemotherapy on survival following gastrectomy for carcinoma: covariate interaction with immunosuppressive acidic protein, a serum marker for the host immune system. Tumor Marker Committee for the Study Group of Immunochemotherapy with PSK for Gastric Cancer.
Surgery today 1999;29(6):504-10.
1998: Y Takagi; H Koumura; M Futamura; S Aoki; K Ymaguchi; H Kida; Hiromi Tanemura; K Shimokawa; Shigetoyo Saji
Somatic alterations of the SMAD-2 gene in human colorectal cancers.
British journal of cancer 1998;78(9):1152-5.
1998: T Ito; M Yamada; Hiromi Tanemura; Hidefumi Oshita; M Asano; Shigetoyo Saji
[Results of combination therapy of UFT-E with low-dose CDDP for patients with advanced recurrent breast cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1998;25(10):1575-80.
1998: Y Yamamura; I Miyazaki; M Ogawa; Y Yonemura; Hiromi Tanemura; T Kito; N Hamajima; Shigetoyo Saji; T Kosaka
[A randomized controlled trial with methotrexate (MTX), 5-fluorouracil (5-FU) and pirarubicin (THP) vs 5-FU alone in advanced or recurrent gastric carcinoma. Tokai Hokuriku THP Study Group].
Gan to kagaku ryoho. Cancer & chemotherapy 1998;25(10):1543-8.
1998: Kiichi Miya; T Adachi; Narutoshi Nagao; Yukihiro Takagi; Yoshihiro Kawaguchi; Masayasu Kato; Hiroshi Takao; Yasuyuki Sugiyama; Katsuyuki Kunieda; T Umemoto; D Fukada; Shigetoyo Saji
[Clinical evaluation of intermittent hepatic arterial infusion therapy for metastatic liver tumor of gastric and colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1998;25(9):1397-401.
1998: M Futamura; Y Takagi; H Koumura; H Kida; Hiromi Tanemura; K Shimokawa; Shigetoyo Saji
Spread of colorectal cancer micrometastases in regional lymph nodes by reverse transcriptase-polymerase chain reactions for carcinoembryonic antigen and cytokeratin 20.
Journal of surgical oncology 1998;68(1):34-40.
1998: Masayasu Kato; Shigetoyo Saji; Masayuki Kanematsu; D Fukada; Kiichi Miya; T Umemoto; Katsuyuki Kunieda; Yasuyuki Sugiyama; Hiroshi Takao; M Kawai; Yoshihiro Kawaguchi
Evaluation of angiographically assisted spiral CT in surgical cases of hepatocellular carcinoma considering recurrent cases.
International surgery 1998;83(2):141-5.
1998: T Takahashi; H Konishi; K Kozaki; H Osada; Shigetoyo Saji; T Takahashi; T Takahashi
Molecular analysis of a Myc antagonist, ROX/Mnt, at 17p13.3 in human lung cancers.
Japanese journal of cancer research : Gann 1998;89(4):347-51.
1998: A Suzuki; Masakazu Toi; Y Yamamoto; Shigetoyo Saji; Mariko Muta; T Tominaga
Role of MDM2 overexpression in doxorubicin resistance of breast carcinoma.
Japanese journal of cancer research : Gann 1998;89(2):221-7.
1998: T Adachi; M Takeuchi; M Nagata; Masayasu Kato; Kiichi Miya; Shigetoyo Saji
Sustained induction of hepatocyte growth factor by sensitization with freeze-thawed hepatic tissue.
Journal of hepato-biliary-pancreatic surgery 1998;5(3):320-6.
1997: Shigetoyo Saji; K Aiba; Hiroshi Araki; Kazuaki Sasaki; Tetsuhiko Shirasaka; M Sowa; M Tanaka; Y Chung; Tetsuya Toge; Koichi Hirata; K Yasumoto; Susumu Yamamitsu; H Wada
[Current status of low-dose CDDP. 5-FU therapy for solid malignant tumors--nationwide questionnaire survey].
Gan to kagaku ryoho. Cancer & chemotherapy 1997;24(13):1892-900.
1997: T Adachi; Shigeru Nakashima; Shigetoyo Saji; Toshikazu Nakamura; Yoshinori Nozawa
Possible involvement of pertussis toxin-sensitive G protein in hepatocyte growth factor-induced signal transduction in cultured rat hepatocytes: pertussis toxin treatment inhibits activation of phospholipid signaling, calcium oscillation, and mitogen-activated protein kinase.
Hepatology (Baltimore, Md.) 1997;26(2):295-300.
1997: H Koumura; Yasuyuki Sugiyama; Katsuyuki Kunieda; Shigetoyo Saji
[Significance in gene expression of matrix metalloproteinase-9, urokinase-type plasminogen activator and tissue inhibitor of metalloproteinase for metastases of gastric and/or colo-rectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1997;24 Suppl 2():324-31.
1997: Masayasu Kato; Shigetoyo Saji; Masayuki Kanematsu; D Fukada; Kiichi Miya; T Umemoto; Katsuyuki Kunieda; Yasuyuki Sugiyama; I Kuwahara; Kuniyasu Shimokawa
A case of liver metastasis from colon cancer masquerading as focal sparing in a fatty liver.
Japanese journal of clinical oncology 1997;27(3):189-92.
1997: Shigetoyo Saji; Yasuyuki Sugiyama; Katsuyuki Kunieda
Pre- and/or post-operative immunochemotherapy for advanced digestive cancer.
Gan to kagaku ryoho. Cancer & chemotherapy 1997;24 Suppl 1():239-49.
1997: M Kato; Shigetoyo Saji; Katsuyuki Kunieda; T Yasue; K Nishio; M Adachi
Mediastinal lipoma: report of a case.
Surgery today 1997;27(8):766-8.
1997: Masayasu Kato; Shigetoyo Saji; H Tsuya; Kiichi Miya; D Fukada; T Umemoto; Katsuyuki Kunieda; Hiroshi Takao; Yasuyuki Sugiyama; K Tsuji; M Sato
Clinical study of the relationship between cytological behavior and postoperative prognosis in colorectal cancer cases with special reference to nuclear DNA content and nucleolar organizer regions.
Journal of surgical oncology 1997;64(1):36-41.
1996: M Kato; Shigetoyo Saji; Masayuki Kanematsu; H Hoshi; T Ishiguchi; Katsuyuki Kunieda; Hiroshi Takao; Yasuyuki Sugiyama
Palliative therapy using polyurethane-covered self-expandable metallic stents for malignant esophageal strictures: experiences in six patients.
Japanese journal of clinical oncology 1996;26(6):461-4.
1996: T Adachi; Shigeru Nakashima; Shigetoyo Saji; T Nakamura; Yoshinori Nozawa
Phospholipase D activation in hepatocyte growth factor-stimulated rat hepatocytes mediates the expressions of c-jun and c-fos: involvement of protein tyrosine kinase, protein kinase C, and Ca2+.
Hepatology (Baltimore, Md.) 1996;24(5):1274-81.
1996: Y Takagi; H Kohmura; M Futamura; H Kida; Hiromi Tanemura; Kuniyasu Shimokawa; Shigetoyo Saji
Somatic alterations of the DPC4 gene in human colorectal cancers in vivo.
Gastroenterology 1996;111(5):1369-72.
1996: Yasuyuki Sugiyama; Shigetoyo Saji; Kiichi Miya; D Fukada; T Umemoto; Katsuyuki Kunieda; Hiroshi Takao; M Kato; M Kawai
[Locoregional therapy for liver metastases of colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1996;23(11):1433-6.
1996: D Fukada; Shigetoyo Saji; Yoshihiro Kawaguchi; M Nagata; Kuniyasu Shimokawa; T Furuta
[Distributions of pyrimidine nucleoside phosphorylase (PyNPase) in tissues of benign and malignant mammary diseases--immunohistochemical observations].
Gan to kagaku ryoho. Cancer & chemotherapy 1996;23(6):703-6.
1996: T Adachi; Shigeru Nakashima; Shigetoyo Saji; T Nakamura; Yoshinori Nozawa
Mitogen-activated protein kinase activation in hepatocyte growth factor-stimulated rat hepatocytes: involvement of protein tyrosine kinase and protein kinase C.
Hepatology (Baltimore, Md.) 1996;23(5):1244-53.
1995: T Imaeda; R Mochizuki; Masayuki Kanematsu; Y Yamawaki; H Goto; M Seki; H Doi; Shigetoyo Saji; Kuniyasu Shimokawa
Hemodynamics of small hepatocellular carcinomas (5 cm or less in diameter): cases with discrepant findings between dynamic MR images and hepatic arteriograms.
Abdominal imaging 1995;20(6):534-40.
1995: Yasuyuki Sugiyama; Shigetoyo Saji; Kiichi Miya; D Fukada; T Umemoto; Katsuyuki Kunieda; Hiroshi Takao; M Kato; K Tsuji
[A new modality of locoregional chemotherapy based on biochemical double modulation of 5-fluorouracil with both leucovorin and cisplatin against liver metastases of colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1995;22(11):1460-3.
1995: T Adachi; Shigeru Nakashima; Shigetoyo Saji; T Nakamura; Yoshinori Nozawa
Roles of prostaglandin production and mitogen-activated protein kinase activation in hepatocyte growth factor-mediated rat hepatocyte proliferation.
Hepatology (Baltimore, Md.) 1995;21(6):1668-74.
1994: T Imaeda; Masayuki Kanematsu; R Mochizuki; H Goto; Shigetoyo Saji; Kuniyasu Shimokawa
Extracapsular invasion of small hepatocellular carcinoma: MR and CT findings.
Journal of computer assisted tomography 1994;18(5):755-60.
1994: T Hashimoto; Shigetoyo Saji; D Fukada; T Umemoto; Katsuyuki Kunieda; Yasuyuki Sugiyama; M Asano; T Chikaishi
[Studies on adjuvant chemotherapy using subserosal or submucosal administration of neocarzinostatin for gastric cancer and colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1994;21(13):2302-4.
1994: S Osada; Yukio Okano; Shigetoyo Saji; Yoshinori Nozawa
Spontaneous Ca2+ release from a caffeine and ryanodine-sensitive intracellular Ca2+ store in freshly prepared hepatocytes.
Hepatology (Baltimore, Md.) 1994;19(2):514-7.
1993: Yasuyuki Sugiyama; M Kato; Hiroshi Takao; H Kida; Katsuyuki Kunieda; T Umemoto; Kiichi Miya; S Azuma; T Furuta; Shigetoyo Saji
[Immunological effects of locoregional immunochemotherapy for liver metastases of gastric cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1993;20(11):1461-4.
1993: T Imaeda; Y Yamawaki; M Seki; H Goto; G Iinuma; Masayuki Kanematsu; R Mochizuki; H Doi; Shigetoyo Saji; Kuniyasu Shimokawa
Lipiodol retention and massive necrosis after lipiodol-chemoembolization of hepatocellular carcinoma: correlation between computed tomography and histopathology.
Cardiovascular and interventional radiology 1993;16(4):209-13.
1993: M Kato; Shigetoyo Saji; T Furuta; Hiromi Tanemura; S Azuma; T Nishina; T Kuno; K Takahashi
[A case of secondary leukemia induced by chemotherapy with a CDDP-based regimen for gastric cancer 5 years following radical resection].
Gan to kagaku ryoho. Cancer & chemotherapy 1993;20(1):137-40.
1992: Yasuyuki Sugiyama; Shigetoyo Saji; T Furuta; S Azuma; Kiichi Miya; T Umemoto; Hiroshi Takao; M Kato; A Kanno
[Clinical studies on locoregional immunochemotherapy of peritonitis carcinomatosa].
Gan to kagaku ryoho. Cancer & chemotherapy 1992;19(10 Suppl):1724-7.
1992: Kiichi Miya; Shigetoyo Saji; T Furuta; S Azuma; T Umemoto; Hiroshi Takao; M Katou; A Kanno; N Kaneda; Y Yamawaki
[Significance of antitumor effects and immunological response on endogenously induced LAK therapy for primary or metastatic liver tumor].
Gan to kagaku ryoho. Cancer & chemotherapy 1992;19(10 Suppl):1453-6.
1992: N Kaneda; Shigetoyo Saji; T Kashizuka; M Kawai; Yasuyuki Sugiyama; Kiichi Miya
[Experimental studies on antitumor effects of endogenously induced LAK (CTL) therapy for metastatic liver tumor].
Gan to kagaku ryoho. Cancer & chemotherapy 1992;19(10 Suppl):1433-6.
1992: S Osada; Shigetoyo Saji; T Nakamura; Yoshinori Nozawa
Cytosolic calcium oscillations induced by hepatocyte growth factor (HGF) in single fura-2-loaded cultured hepatocytes: effects of extracellular calcium and protein kinase C.
Biochimica et biophysica acta 1992;1135(2):229-32.
1992: S Osada; Shigeru Nakashima; Shigetoyo Saji; T Nakamura; Yoshinori Nozawa
Hepatocyte growth factor (HGF) mediates the sustained formation of 1,2-diacylglycerol via phosphatidylcholine-phospholipase C in cultured rat hepatocytes.
FEBS letters 1992;297(3):271-4.
1991: Shigetoyo Saji; Hiromi Tanemura; Katsuyuki Kunieda; Y Sugiyama
[Recent advance and its problem of postoperative immunotherapy on gastric cancer--with references to effects and host dependent factors].
Nihon Geka Gakkai zasshi 1991;92(9):1221-4.
1991: Kiichi Miya; Shigetoyo Saji; T Furuta; Hiromi Tanemura; S Azuma; T Umemoto; Katsuyuki Kunieda; Hiroshi Takao; Yasuyuki Sugiyama; M Kawai
[Therapeutic effect of transarterial infusion immunochemotherapy for metastatic liver cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1991;18(11):1992-5.
1991: Hiromi Tanemura; S Azuma; Shigetoyo Saji; R Kawata; T Furuta; Kiichi Miya; T Umemoto; Katsuyuki Kunieda; Hiroshi Takao; Yasuyuki Sugiyama
[A long-term survival case of advanced gastric cancer undergoing radical gastrectomy by second-look operation after successful chemotherapy (CDDP, MMC, 5-FU)].
Gan to kagaku ryoho. Cancer & chemotherapy 1991;18(10):1695-8.
1991: M Asano; Shigetoyo Saji; Hiromi Tanemura; Katsuyuki Kunieda; T Chikaishi; T Andou
[Usefulness of subserosal administration of neocarzinostatin (NCS) for the regional lymph node metastasis in gastric cancer: preliminary report].
Nihon Geka Gakkai zasshi 1991;92(5):617.
1991: T Kageyama; T Chikaishi; N Kaneda; H Takahashi; Katsuyuki Kunieda; Hiromi Tanemura; Shigetoyo Saji
[Correlation among operative prognosis, histological CEA localization and cellular DNA content on gastric cancer patients: preliminary report].
Nihon Geka Gakkai zasshi 1991;92(2):227.
1990: Hiromi Tanemura; Shigetoyo Saji; T Chikaishi; T Kageyama; S Azuma; T Furuta; S Tanaka; H Kachi; Kuniyasu Shimokawa; K Kato
[Relationship between the prognosis and nuclear DNA histograms in gastric cancer patients with a synchronous liver metastases who were given a combined gastrectomy and hepatectomy].
Gan no rinsho. Japan journal of cancer clinics 1990;36(15):2541-5.
1990: Yasuyuki Sugiyama; A Yoshida; Hiroshi Takao; Katsuyuki Kunieda; Kiichi Miya; S Azuma; Hiromi Tanemura; T Furuta; Shigetoyo Saji
[Intraoperative intraperitoneal administration of mitomycin C and OK-432 for peritoneal dissemination of gastric cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 1990;17(8 Pt 2):1592-5.
1990: T Suhara; S Azuma; M Hayakawa; M Futamura; A Yoshida; N Kaneda; T Kageyama; Hiromi Tanemura; T Furuta; Shigetoyo Saji
[A case of metastatic malignant melanoma of the stomach treated by a surgical operation].
Gan no rinsho. Japan journal of cancer clinics 1990;36(8):934-8.
1990: Katsuyuki Kunieda; A Onishi; S Azuma; T Furuta; Shigetoyo Saji; K Sakata; T Kunieda
[Examination of the rectosphincteric reflex by means of endoscopic electrical stimulation. A new device].
Nihon Geka Gakkai zasshi 1990;91(4):472-80.
1990: Katsuyuki Kunieda; K Yasuda; T Hashimoto; T Shiroko; S Azuma; T Furuta; Shigetoyo Saji; Kuniyasu Shimokawa
[Two cases of primary, diffusely infiltrating carcinoma (linitis plastica) of the colon].
Gan no rinsho. Japan journal of cancer clinics 1990;36(5):657-62.
1989: T Chikaishi; Hiromi Tanemura; Shigetoyo Saji; K Kato; Kuniyasu Shimokawa
[Relationship between the effectiveness of CDDP therapy and the nuclear DNA content in advanced-recurrent gastric cancer cases].
Gan no rinsho. Japan journal of cancer clinics 1989;35(15):1739-44.
1989: H Goshima; Shigetoyo Saji; T Furuta; H Taneumura; Hiroshi Takao; H Kida; H Takahashi
[Experimental study on preventive effects of lung metastases using LAK cells induced from various lymphocytes--special references to enhancement of lung metastasis after laparotomy stress].
Nihon Geka Gakkai zasshi 1989;90(8):1245-50.
1989: H Goshima; Shigetoyo Saji; Hiromi Tanemura; Hiroshi Takao; S Tachibana; T Oiwa; I Keshikawa
[In vivo antitumor effect of LAK cells induced from various lymphocytes--experimental study in rats].
Nihon Geka Gakkai zasshi 1989;90(7):972-9.
1988: H Kida; Shigetoyo Saji; H Goshima; S Tachibana; Y Kunii; Hiromi Tanemura; K Sakata
[Facilitation of tumor metastasis to the lung by operative stress in the rat--influence of adrenocortical hormones and preoperative administration of OK-432].
Nihon Geka Gakkai zasshi 1988;89(10):1692-8.
1988: Katsuyuki Kunieda; M Wakahara; T Ando; N Takenouchi; T Chujo; S Azuma; Shigetoyo Saji; K Sakata; Kuniyasu Shimokawa
[Malignant melanoma in the anorectal region--a report of two cases].
Gan no rinsho. Japan journal of cancer clinics 1988;34(11):1613-8.
1988: T Umemoto; Shigetoyo Saji; H Enami; Y Kunii; H Goshima; S Tachibana; Hiroshi Takao; K Sakata
[Antitumor activity of neutrophils induced by a nonspecific immunopotentiator OK-432. III. Experimental study using human peripheral neutrophils].
Nihon Gan Chiryo Gakkai shi 1988;23(7):1518-24.
1988: T Umemoto; Shigetoyo Saji; A Oonishi; Y Kunii; H Goshima; S Tachibana; Hiroshi Takao; Hiromi Tanemura; K Sakata
[Antitumor activity of neutrophils induced by a nonspecific immunopotentiator OK-432. II. Experimental study using human malignant ascites].
Nihon Gan Chiryo Gakkai shi 1988;23(7):1512-7.
1988: Hiroshi Takao; Shigetoyo Saji; Y Sugiyama; S Tachibana; H Goshima; Y Kunii; K Sakata
[Effects of serum immunosuppressive factors on the cytotoxicity of lymphokine-activated killer (LAK) cells induced by recombinant interleukin 2(R-IL2)].
Nihon Geka Gakkai zasshi 1988;89(7):992-8.
1988: T Umemoto; Shigetoyo Saji; H Minatsu; Y Kunii; H Goshima; S Tachibana; Hiroshi Takao; K Sakata
[Antitumor activity of neutrophils induced by a nonspecific immunopotentiator OK-432. I. Experimental study using a rat model of malignant ascites].
Nihon Gan Chiryo Gakkai shi 1988;23(6):1229-35.
1988: K Kato; Y Bunai; T Kuniyasu; N Yoshimi; H Mori; Shigetoyo Saji; K Sakata
Immunohistochemical localization of human lung adenocarcinoma-associated antigen with a monoclonal antibody.
Japanese journal of clinical oncology 1988;18(2):105-12.
1988: Hiroshi Takao; Shigetoyo Saji; Y Sugiyama; S Tachibana; H Goshima; T Morita; K Sakata
[Experimental studies on induction of various lymphokine-activated killer cells using recombinant interleukin 2].
Nihon Geka Gakkai zasshi 1988;89(5):646-54.
1988: Hiromi Tanemura; R Kawata; M Suzuki; Kuniyasu Shimokawa; S Azuma; T Furuta; Shigetoyo Saji; H Ohashi; K Sakata
Cure of advanced gastric cancer by combined chemotherapy with cisplatinum, mitomycin C, and 5-fluorouracil.
Journal of surgical oncology 1988;38(1):26-32.
1987: Katsuyuki Kunieda; T Hatoh; Shigetoyo Saji; K Sakata; A Takamura; Y Mutoh; A Yamamoto; H Katoh; S Sawai; Kuniyasu Shimokawa
[Triple primary malignancies (malignant melanoma, laryngeal cancer and hepatoma)].
Gan no rinsho. Japan journal of cancer clinics 1987;33(15):1923-8.
1987: Shigetoyo Saji; Y Kishimoto; K Sakata; T Furuta; Hiromi Tanemura; R Kawata
Advanced gastric cancer successfully resected following cisplatin therapy: report of a case.
Journal of surgical oncology 1987;36(2):138-41.
1987: Hiromi Tanemura; Shigetoyo Saji; Hiroshi Takao; H Kida; Katsuyuki Kunieda; Kiichi Miya; S Azuma; T Furuta; K Sakata; Kuniyasu Shimokawa
[Experience with CDDP therapy in advanced and recurrent gastric cancer cases].
Gan to kagaku ryoho. Cancer & chemotherapy 1987;14(10):2951-5.
1987: Hiromi Tanemura; R Kawata; M Suzuki; Kuniyasu Shimokawa; H Tsuya; T Ando; S Azuma; T Furuta; Shigetoyo Saji; H Ohashi
[Successful treatment of advanced gastric cancer by combined cisplatinum, mitomycin C and 5-FU administration. A case report].
Gan to kagaku ryoho. Cancer & chemotherapy 1987;14(3 Pt 1):728-31.
1986: Shigetoyo Saji; Y Yokoyama; H Niwa; Hiroshi Takao; H Kida; R Kawata; Hiromi Tanemura; K Sakata
Clinical studies on serum immunosuppressive acidic protein (IAP) and ferritin in gastric cancer patients: with special reference to preoperative value and influence of surgical stress.
Journal of surgical oncology 1986;33(4):215-22.
1986: Kiichi Miya; Shigetoyo Saji; T Morita; H Niwa; Hiroshi Takao; Y Kunii; K Sakata
[Experimental study on the absorption mechanism of cryo-necrotized tumor antigens].
Nihon Geka Gakkai zasshi 1986;87(5):482-7.
1986: Y Kishimoto; Shigetoyo Saji; T Ishikawa; H Takahashi; R Kawata; Hiromi Tanemura; T Furuta; H Ohashi; K Sakata; Kuniyasu Shimokawa
[Advanced gastric cancer successfully resected following cisplatin therapy. A case report].
Gan to kagaku ryoho. Cancer & chemotherapy 1986;13(1):139-42.
1985: H Oshita; Shigetoyo Saji; Y Sugiyama; Hiromi Tanemura; K Sakata; S Tanaka; T Ito
[Observation on natural killer cell activity in gastric cancer patients and effect of nonspecific immunopotentiator administration on its postoperative reduction].
Nihon Geka Gakkai zasshi 1985;86(10):1417-25.
1985: Y Yokoyama; Shigetoyo Saji; H Misao; Y Kunii; T Kajima; Katsuyuki Kunieda; T Nishiwaki; Y Adachi; R Kawata; K Sakata
[Clinical study on serum immunosuppressive factors in gastric cancer patients--with special reference to preoperative ferritin levels and influence of surgical stress].
Gan no rinsho. Japan journal of cancer clinics 1985;31(11):1387-92.
1985: Y Yokoyama; Shigetoyo Saji; H Niwa; Hiroshi Takao; H Kida; T Umemoto; R Kawata; K Sakata; S Tanaka
[Clinical study on serum immunosuppressive factors in gastric cancer patients--with special reference to preoperative IAP values and the influence of surgical stress].
Gan no rinsho. Japan journal of cancer clinics 1985;31(10):1275-80.
1985: A Misao; Shigetoyo Saji; Y Hosono; T Takekoshi; S Tanaka; Y Sato; N Mori; S Yasui; I Kuriyama
[Monthly changes in serum alpha 2-globulin and immunoglobulin levels in chronic hemodialysis patients--with special reference to the occurrence of cancer and blood transfusion].
Gan no rinsho. Japan journal of cancer clinics 1985;31(8):953-8.
1985: S Yamamoto; Shigetoyo Saji; Y Sugiyama; H Kida; T Umemoto; Kiichi Miya; H Oshita; Y Yokoyama; T Takekoshi; K Sakata
[Relations of tumor-specific cytotoxicity to nonspecific immunological parameters and to clinical course in various surgical cancer patients].
Nihon Geka Gakkai zasshi 1985;86(3):251-7.
1985: S Yamamoto; K Sakata; T Kunieda; Shigetoyo Saji; Hiromi Tanemura; T Takekoshi; Y Sugiyama
Relationship between lymphocytic cytotoxicity and phytohemagglutinin-induced lymphoblastogenesis before and after surgical tumor excision: an experimental study.
Journal of surgical oncology 1985;28(1):42-9.
1984: T Takekoshi; Shigetoyo Saji; T Kida; T Umemoto; Kiichi Miya; H Oshita; Y Yokoyama; S Yamamoto; Hiromi Tanemura; T Kunieda
[Clinical studies on preoperative nonspecific immunological parameters and radical operation in stomach cancer].
Nihon Geka Gakkai zasshi 1984;85(12):1528-36.
1984: T Kunieda; R Kawata; K Nayashi; T Nishiwaki; Katsuyuki Kunieda; Shigetoyo Saji; K Sakata
[Experimental study on quantitative evaluation of fatty liver by computed tomography].
Nihon Geka Gakkai zasshi 1984;85(11):1472-8.
1984: T Takekoshi; K Sakata; T Kunieda; Shigetoyo Saji; Hiromi Tanemura; S Yamamoto
Facilitation of tumor metastasis by operative stress and participation of cell-mediated immunity. Experimental study.
Oncology 1984;41(4):245-51.
1983: Hiromi Tanemura; Shigetoyo Saji; T Takekoshi; S Yamamoto; H Oshita; K Sakata
[Experimental study on immunological effect of splenectomy on tumor-bearers].
Nihon Geka Gakkai zasshi 1983;84(9):982-6.
1983: Shigetoyo Saji; H Oshita; S Yamamoto; T Takekoshi; K Sakata
Experimental study on merits and demerits of splenectomy in tumor bearers.
Journal of surgical oncology 1983;23(1):35-40.
1983: Shigetoyo Saji; Y Sugiyama; Kiichi Miya; H Oshita; Y Yokoyama; S Yamamoto; T Takekoshi; K Sakata
[Immunological effect of splenectomy in tumor-bearing rat].
Nihon Geka Gakkai zasshi 1983;84(3):179-85.
1982: Shigetoyo Saji; Kiichi Miya; H Oshita; O Nonomura; Y Yokoyama; S Yamamoto; T Takekoshi; K Sakata
[Antitumor effect of intraperitoneal administration of a streptococcal preparation, OK-432, in carcinomatous peritonitis. I. Experimental study in the rat].
Gan to kagaku ryoho. Cancer & chemotherapy 1982;9(11):1961-8.
1982: Hiromi Tanemura; K Sakata; T Kunieda; Shigetoyo Saji; S Yamamoto; T Takekoshi
Influences of operative stress on cell-mediated immunity and on tumor metastasis and their prevention by nonspecific immunotherapy: experimental studies in rats.
Journal of surgical oncology 1982;21(3):189-95.