Hironao Sajiki

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Maegawa Tomohiro; Akashi Akira; Yaguchi Kiichiro; Iwasaki Yohei; Shigetsura Masahiro; Monguchi Yasunari; Sajiki Hironao
Efficient and practical arene hydrogenation by heterogeneous catalysts under mild conditions.
Maegawa Tomohiro; Fujiwara Yuta; Ikawa Takashi; Hisashi Hideo; Monguchi Yasunari; Sajiki Hironao
Novel deprotection method of Fmoc group under neutral hydrogenation conditions.
Inokuchi Yuta; Nakajima Yoshimi; Shimazawa Masamitsu; Kurita Takanori; Kubo Mikiko; Saito Atsushi; Sajiki Hironao; Kudo Takashi; Aihara Makoto; Imaizumi Kazunori; Araie Makoto; Hara Hideaki
Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum (ER) stress-induced retinal cell death.

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2009: Maegawa Tomohiro; Akashi Akira; Yaguchi Kiichiro; Iwasaki Yohei; Shigetsura Masahiro; Monguchi Yasunari; Sajiki Hironao
Efficient and practical arene hydrogenation by heterogeneous catalysts under mild conditions.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(28):6953-63.
2009: Maegawa Tomohiro; Fujiwara Yuta; Ikawa Takashi; Hisashi Hideo; Monguchi Yasunari; Sajiki Hironao
Novel deprotection method of Fmoc group under neutral hydrogenation conditions.
Amino acids 2009;36(3):493-9.
2009: Inokuchi Yuta; Nakajima Yoshimi; Shimazawa Masamitsu; Kurita Takanori; Kubo Mikiko; Saito Atsushi; Sajiki Hironao; Kudo Takashi; Aihara Makoto; Imaizumi Kazunori; Araie Makoto; Hara Hideaki
Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum (ER) stress-induced retinal cell death.
Investigative ophthalmology & visual science 2009;50(1):334-44.
2009: Modutlwa Nkaelang; Tada Hiroyuki; Sugahara Yoshiki; Shiraki Koichi; Hara Nobuyuki; Deyashiki Yoshihiro; Ando Takayuki; Maegawa Tomohiro; Monguchi Yasunari; Sajiki Hironao
Synthesis of deuterated benzyladenine and its application as a surrogate.
Nucleic acids symposium series (2004) 2009;(53):105-6.
2009: Mutsumi Tomonobu; Maruhashi Kazuo; Monguchi Yasunari; Sajiki Hironao
Alternative I-D exchange reaction on pyrimidine and purine nuclei mediated by tributyltin hydride using THF-d8 as a deuterium source.
Nucleic acids symposium series (2004) 2009;(53):3-4.
2009: Monguchi Yasunari; Fujita Yuki; Endo Koichi; Takao Shinobu; Yoshimura Masatoshi; Takagi Yukio; Maegawa Tomohiro; Sajiki Hironao
A highly active heterogeneous palladium catalyst supported on a synthetic adsorbent.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(4):834-7.
2008: Mori Shigeki; Yanase Takayoshi; Aoyagi Satoka; Monguchi Yasunari; Maegawa Tomohiro; Sajiki Hironao
Ligand-free Sonogashira coupling reactions with heterogeneous Pd/C as the catalyst.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(23):6994-9.
2008: Maegawa Tomohiro; Fujiwara Yuta; Inagaki Yuya; Esaki Hiroyoshi; Monguchi Yasunari; Sajiki Hironao
Mild and efficient H/D exchange of alkanes based on C-H activation catalyzed by rhodium on charcoal.
Angewandte Chemie (International ed. in English) 2008;47(29):5394-7.
2008: Sajiki Hironao; Mori Shigeki; Ohkubo Tomoyuki; Ikawa Takashi; Kume Akira; Maegawa Tomohiro; Monguchi Yasunari
Partial hydrogenation of alkynes to cis-olefins by using a novel Pd(0)-polyethyleneimine catalyst.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(17):5109-11.
2008: Kurita Takanori; Aoki Fumiyo; Mizumoto Takuto; Maejima Toshihide; Esaki Hiroyoshi; Maegawa Tomohiro; Monguchi Yasunari; Sajiki Hironao
Facile and convenient method of deuterium gas generation using a Pd/C-catalyzed H2-D2 exchange reaction and its application to synthesis of deuterium-labeled compounds.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(11):3371-9.
2008: Kurita Takanori; Hattori Kazuyuki; Seki Saori; Mizumoto Takuto; Aoki Fumiyo; Yamada Yuki; Ikawa Kanoko; Maegawa Tomohiro; Monguchi Yasunari; Sajiki Hironao
Efficient and convenient heterogeneous palladium-catalyzed regioselective deuteration at the benzylic position.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(2):664-73.
2007: Kitamura Yoshiaki; Sako Satoko; Udzu Takahiro; Tsutsui Azusa; Maegawa Tomohiro; Monguchi Yasunari; Sajiki Hironao
Ligand-free Pd/C-catalyzed Suzuki-Miyaura coupling reaction for the synthesis of heterobiaryl derivatives.
Chemical communications (Cambridge, England) 2007;(47):5069-71.
2007: Tyeklar Zoltan; Dunham Stephen U; Midelfort Katarina; Scott Daniel M; Sajiki Hirano; Ong Karen; Lauffer Randall B; Caravan Peter; McMurry Thomas J
Structural, kinetic, and thermodynamic characterization of the interconverting isomers of MS-325, a gadolinium(III)-based magnetic resonance angiography contrast agent.
Inorganic chemistry 2007;46(16):6621-31.
2007: Maegawa Tomohiro; Fujita Yuki; Sakurai Ai; Akashi Akira; Sato Mutsumi; Oono Keiji; Sajiki Hironao
Pd/C(en) catalyzed chemoselective hydrogenation in the presence of aryl nitriles.
Chemical & pharmaceutical bulletin 2007;55(5):837-9.
2007: Esaki Hiroyoshi; Ohtaki Rumi; Maegawa Tomohiro; Monguchi Yasunari; Sajiki Hironao
Novel Pd/C-catalyzed redox reactions between aliphatic secondary alcohols and ketones under hydrogenation conditions: application to H-D exchange reaction and the mechanistic study.
The Journal of organic chemistry 2007;72(6):2143-50.
2007: Maegawa Tomohiro; Kitamura Yoshiaki; Sako Satoko; Udzu Takahiro; Sakurai Ai; Tanaka Asami; Kobayashi Yusuke; Endo Koichi; Bora Utpal; Kurita Takanori; Kozaki Atsushi; Monguchi Yasunari; Sajiki Hironao
Heterogeneous Pd/C-catalyzed ligand-free, room-temperature Suzuki-Miyaura coupling reactions in aqueous media.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(20):5937-43.
2007: Esaki Hiroyoshi; Aoki Fumiyo; Umemura Miho; Kato Masatsugu; Maegawa Tomohiro; Monguchi Yasunari; Sajiki Hironao
Efficient h/d exchange reactions of alkyl-substituted benzene derivatives by means of the Pd/C-H(2)-D(2)O system.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(14):4052-63.
2007: Mori Akinori; Mizusaki Tomoteru; Ikawa Takashi; Maegawa Tomohiro; Monguchi Yasunari; Sajiki Hironao
Mechanistic study of a Pd/C-catalyzed reduction of aryl sulfonates using the Mg-MeOH-NH(4)OAc system.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(5):1432-41.
2006: Mori Akinori; Miyakawa Yumi; Ohashi Eri; Haga Tomoko; Maegawa Tomohiro; Sajiki Hironao
Pd/C-catalyzed chemoselective hydrogenation in the presence of diphenylsulfide.
Organic letters 2006;8(15):3279-81.
2006: Sajiki Hironao; Mori Akinori; Mizusaki Tomoteru; Ikawa Takashi; Maegawa Tomohiro; Hirota Kosaku
Pd/C-catalyzed deoxygenation of phenol derivatives using Mg metal and MeOH in the presence of NH(4)OAc.
Organic letters 2006;8(5):987-90.
2005: Maegawa Tomohiro; Hirota Kosaku; Tatematsu Kenjiro; Mori Yukio; Sajiki Hironao
Facile and efficient postsynthetic tritium labeling method catalyzed by Pd/C in HTO.
The Journal of organic chemistry 2005;70(25):10581-3.
2004: Sajiki Hironao; Ikawa Takashi; Hirota Kosaku
Reductive and catalytic monoalkylation of primary amines using nitriles as an alkylating reagent.
Organic letters 2004;6(26):4977-80.
2004: Sajiki Hironao; Kurita Takanori; Esaki Hiroyoshi; Aoki Fumiyo; Maegawa Tomohiro; Hirota Kosaku
Complete replacement of H2 by D2 via Pd/C-catalyzed H/D exchange reaction.
Organic letters 2004;6(20):3521-3.
2004: Sajiki Hironao; Aoki Fumiyo; Esaki Hiroyoshi; Maegawa Tomohiro; Hirota Kosaku
Efficient C-H/C-D exchange reaction on the alkyl side chain of aromatic compounds using heterogeneous Pd/C in D2O.
Organic letters 2004;6(9):1485-7.
2004: Kurimoto Ayumu; Ogino Tetsuhiro; Ichii Shinji; Isobe Yoshiaki; Tobe Masanori; Ogita Haruhisa; Takaku Haruo; Sajiki Hironao; Hirota Kosaku; Kawakami Hajime
Synthesis and evaluation of 2-substituted 8-hydroxyadenines as potent interferon inducers with improved oral bioavailabilities.
Bioorganic & medicinal chemistry 2004;12(5):1091-9.
2004: Takasu Hideki; Tsuji Yoshie; Sajiki Hironao; Hirota Kosaku
Modification of the sugar moiety in uridine via 2',3'-epoxyuridine derivatives.
Nucleic acids symposium series (2004) 2004;(48):49-50.
2003: Kurimoto Ayumu; Ogino Tetsuhiro; Ichii Shinji; Isobe Yoshiaki; Tobe Masanori; Ogita Haruhisa; Takaku Haruo; Sajiki Hironao; Hirota Kosaku; Kawakami Hajime
Synthesis and structure-activity relationships of 2-amino-8-hydroxyadenines as orally active interferon inducing agents.
Bioorganic & medicinal chemistry 2003;11(24):5501-8.
2003: Isobe Yoshiaki; Tobe Masanori; Ogita Haruhisa; Kurimoto Ayumu; Ogino Tetsuhiro; Kawakami Hajime; Takaku Haruo; Sajiki Hironao; Hirota Kosaku; Hayashi Hideya
Synthesis and structure-activity relationships of 2-substituted-8-hydroxyadenine derivatives as orally available interferon inducers without emetic side effects.
Bioorganic & medicinal chemistry 2003;11(17):3641-7.
2003: Hirota Kosaku; Kazaoka Kazunori; Sajiki Hironao
Synthesis and biological evaluation of 2,8-disubstituted 9-benzyladenines: discovery of 8-mercaptoadenines as potent interferon-inducers.
Bioorganic & medicinal chemistry 2003;11(13):2715-22.
2003: Kazaoka Kazunori; Sajiki Hironao; Hirota Kosaku
Synthesis of 6-substituted 9-benzyl-8-hydroxypurines with potential interferon-inducing activity.
Chemical & pharmaceutical bulletin 2003;51(5):608-11.
2003: Hirota Kosaku; Kazaoka Kazunori; Niimoto Itaru; Sajiki Hironao
Efficient synthesis of 2,9-disubstituted 8-hydroxyadenine derivatives.
Organic & biomolecular chemistry 2003;1(8):1354-65.
2003: Sajiki Hironao; Ikawa Takashi; Hattori Kazuyuki; Hirota Kosaku
A remarkable solvent effect toward the Pd/C-catalyzed cleavage of silyl ethers.
Chemical communications (Cambridge, England) 2003;(5):654-5.
2003: Sajiki Hironao; Hirota Kosaku
Pd/C-catalyzed chemoselective hydrogenation in the presence of a phenolic MPM protective group using pyridine as a catalyst poison.
Chemical & pharmaceutical bulletin 2003;51(3):320-4.
2003: Sajiki Hironao; Aoki Fumiyo; Esaki Hiroyoshi; Maegawa Tomohiro; Hirota Kosaku
Palladium-catalyzed H-D exchange into nucleic acids in deuterium oxide.
Nucleic acids research. Supplement (2001) 2003;(3):55-6.
2002: Hirota Kosaku; Kazaoka Kazunori; Niimoto Itaru; Kumihara Hiroshi; Sajiki Hironao; Isobe Yoshiaki; Takaku Haruo; Tobe Masanori; Ogita Haruhisa; Ogino Tetsuhiro; Ichii Shinji; Kurimoto Ayumu; Kawakami Hajime
Discovery of 8-hydroxyadenines as a novel type of interferon inducer.
Journal of medicinal chemistry 2002;45(25):5419-22.
2002: McMurry Thomas J; Parmelee David J; Sajiki Hironao; Scott Daniel M; Ouellet Hillori S; Walovitch Richard C; Tyeklár Zoltán; Dumas Stéphane; Bernard Paul; Nadler Samuel; Midelfort Katarina; Greenfield Matthew; Troughton Jeffrey; Lauffer Randall B
The effect of a phosphodiester linking group on albumin binding, blood half-life, and relaxivity of intravascular diethylenetriaminepentaacetato aquo gadolinium(III) MRI contrast agents.
Journal of medicinal chemistry 2002;45(16):3465-74.
2002: Sajiki Hironao; Yamada Akira; Yasunaga Kanoko; Tsunoda Takashi; Amer Mumen F; Hirota Kosaku
A novel C-C bond formation at the 5-position of uridine derivatives.
Nucleic acids research. Supplement (2001) 2002;(2):13-4.
2000: Hirota K; Hattori R; Sajiki H; Monguchi Y; Muraoka O; Tanabe G
Synthesis of 2,3-dihydroinosine derivatives by reduction using BH3-THF.
Nucleic acids symposium series 2000;(44):113-4.
1998: Kitade Y; Saito N; Kozaki A; Takahashi K; Yatome C; Takeda Y; Sajiki H; Hirota K
Facile method for the preparation of 7-methyl-8-oxoguanosines as an immunomodulator.
Nucleosides & nucleotides 1998;17(1-3):91-7.
1997: Hirota K; Sawada M; Sajiki H; Sako M
Synthesis of 6-aminouracils and pyrrolo[2,3-d]pyrimidine-2,4-diones and their inhibitory effect on thymidine phosphorylase.
Nucleic acids symposium series 1997;(37):59-60.

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Hironao Sajiki

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