Kengo Sakaguchi

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Yanai Takuro; Sakamoto Aiko; Iwabata Kazuki; Koshiyama Akiyo; Sugawara Hiroko; Nara Takayuki; Takakusagi Yoichi; Sakaguchi Kengo
DNA polymerase mu interacts with a meiosis-specific RecA homolog Lim15 during meiosis in Coprinus cinereus.
Matsui Yuki; Hada Takahiko; Maeda Naoki; Sato Yoshihiro; Yamaguchi Yasuhiro; Takeuchi Toshifumi; Takemura Masaharu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth.
Takakusagi Yoichi; Takakusagi Kaori; Sugawara Fumio; Sakaguchi Kengo
[Validation of small-molecule/protein interactions by the T7 phage display strategy using a quartz-crystal microbalance device]

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2009: Yanai Takuro; Sakamoto Aiko; Iwabata Kazuki; Koshiyama Akiyo; Sugawara Hiroko; Nara Takayuki; Takakusagi Yoichi; Sakaguchi Kengo
DNA polymerase mu interacts with a meiosis-specific RecA homolog Lim15 during meiosis in Coprinus cinereus.
Biochemical and biophysical research communications 2009;390(1):32-7.
2009: Matsui Yuki; Hada Takahiko; Maeda Naoki; Sato Yoshihiro; Yamaguchi Yasuhiro; Takeuchi Toshifumi; Takemura Masaharu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structure and activity relationship of monogalactosyl diacylglycerols, which selectively inhibited in vitro mammalian replicative DNA polymerase activity and human cancer cell growth.
Cancer letters 2009;283(1):101-7.
2009: Takakusagi Yoichi; Takakusagi Kaori; Sugawara Fumio; Sakaguchi Kengo
[Validation of small-molecule/protein interactions by the T7 phage display strategy using a quartz-crystal microbalance device]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2009;54(9):1203-9.
2009: Sakaguchi Kengo; Ishibashi Toyotaka; Uchiyama Yukinobu; Iwabata Kazuki
The multi-replication protein A (RPA) system--a new perspective.
The FEBS journal 2009;276(4):943-63.
2009: Sugawara Hiroko; Iwabata Kazuki; Koshiyama Akiyo; Yanai Takuro; Daikuhara Yoko; Namekawa Satoshi H; Hamada Fumika N; Sakaguchi Kengo
Coprinus cinereus Mer3 is required for synaptonemal complex formation during meiosis.
Chromosoma 2009;118(1):127-39.
2009: Uchiyama Yukinobu; Takeuchi Ryo; Kodera Hirofumi; Sakaguchi Kengo
Distribution and roles of X-family DNA polymerases in eukaryotes.
Biochimie 2009;91(2):165-70.
2009: Shiomi Toru; Tsunoda Tatsuo; Kawai Akiko; Matsuura Shun-ichi; Mizukami Fujio; Sakaguchi Kengo
Synthesis of a cagelike hollow aluminosilicate with vermiculate micro-through-holes and its application to ship-in-bottle encapsulation of protein.
Small (Weinheim an der Bergstrasse, Germany) 2009;5(1):67-71.
2008: Kuriyama Isoko; Fukudome Keishi; Kamisuki Shinji; Kuramochi Kouji; Tsubaki Kazunori; Sakaguchi Kengo; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
The specific inhibitory effect of demethoxydehydroaltenusin, a derivative of dehydroaltenusin, on mammalian DNA polymerase alpha.
International journal of molecular medicine 2008;22(6):793-9.
2008: Takakusagi Yoichi; Kuramochi Kouji; Takagi Manami; Kusayanagi Tomoe; Manita Daisuke; Ozawa Hiroko; Iwakiri Kanako; Takakusagi Kaori; Miyano Yuka; Nakazaki Atsuo; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo
Efficient one-cycle affinity selection of binding proteins or peptides specific for a small-molecule using a T7 phage display pool.
Bioorganic & medicinal chemistry 2008;16(22):9837-46.
2008: Nakamura Ryoichi; Takeuchi Ryo; Takata Kei-ichi; Shimanouchi Kaori; Abe Yoko; Kanai Yoshihiro; Ruike Tatsushi; Ihara Ayumi; Sakaguchi Kengo
TRF4 is involved in polyadenylation of snRNAs in Drosophila melanogaster.
Molecular and cellular biology 2008;28(21):6620-31.
2008: Takakusagi Yoichi; Kuroiwa Yuki; Sugawara Fumio; Sakaguchi Kengo
Identification of a methotrexate-binding peptide from a T7 phage display screen using a QCM device.
Bioorganic & medicinal chemistry 2008;16(15):7410-4.
2008: Uchiyama Yukinobu; Takeuchi Ryo; Kodera Hirofumi; Sakaguchi Kengo
[Evolution and functions of X-family DNA polymerases in eukaryotes]
Seikagaku. The Journal of Japanese Biochemical Society 2008;80(7):646-51.
2008: Kubota Munehiro; Nakabayashi Tadashi; Matsumoto Yuki; Shiomi Tohru; Yamada Yusuke; Ino Keita; Yamanokuchi Hiroyuki; Matsui Masayoshi; Tsunoda Tatsuo; Mizukami Fujio; Sakaguchi Kengo
Selective adsorption of bacterial cells onto zeolites.
Colloids and surfaces. B, Biointerfaces 2008;64(1):88-97.
2008: Iwabata Kazuki; Sakaguchi Kengo
Lim15/Dmc1 enhances DNA topoisomerase II catenation activity independent of sequence homology.
Chromosoma 2008;117(3):297-302.
2008: Saitoh Takeki; Kuramochi Kouji; Imai Takahiko; Takata Kei-ichi; Takehara Masahide; Kobayashi Susumu; Sakaguchi Kengo; Sugawara Fumio
Podophyllotoxin directly binds a hinge domain in E2 of HPV and inhibits an E2/E7 interaction in vitro.
Bioorganic & medicinal chemistry 2008;16(10):5815-25.
2008: Mori Yoko; Sahara Hiroeki; Matsumoto Kayo; Takahashi Nobuaki; Yamazaki Takayuki; Ohta Keisuke; Aoki Satoko; Miura Masahiko; Sugawara Fumio; Sakaguchi Kengo; Sato Noriyuki
Downregulation of Tie2 gene by a novel antitumor sulfolipid, 3'-sulfoquinovosyl-1'-monoacylglycerol, targeting angiogenesis.
Cancer science 2008;99(5):1063-70.
2008: Kuramochi Kouji; Yukizawa Shunsuke; Ikeda Seiki; Sunoki Takashi; Arai Satoshi; Matsui Rie; Morita Akinori; Mizushina Yoshiyuki; Sakaguchi Kengo; Sugawara Fumio; Ikekita Masahiko; Kobayashi Susumu
Syntheses and applications of fluorescent and biotinylated epolactaene derivatives: Epolactaene and its derivative induce disulfide formation.
Bioorganic & medicinal chemistry 2008;16(9):5039-49.
2008: Ishii Satomi; Koshiyama Akiyo; Hamada Fumika N; Nara Takayuki Y; Iwabata Kazuki; Sakaguchi Kengo; Namekawa Satoshi H
Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1: a molecular link between recombination and chromatin assembly during meiosis.
The FEBS journal 2008;275(9):2032-41.
2008: Uchiyama Yukinobu; Suzuki Yuko; Sakaguchi Kengo
Characterization of plant XRCC1 and its interaction with proliferating cell nuclear antigen.
Planta 2008;227(6):1233-41.
2008: Mizushina Yoshiyuki; Takeuchi Toshifumi; Takakusagi Yoichi; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Fujita Masatoshi
Inhibitory action of polyunsaturated fatty acids on Cdt1-geminin interaction.
International journal of molecular medicine 2008;21(3):281-90.
2008: Takehara Masahide; Ino Keita; Takakusagi Yoichi; Oshikane Hiroyuki; Nureki Osamu; Ebina Takeo; Mizukami Fujio; Sakaguchi Kengo
Use of layer silicate for protein crystallization: effects of Micromica and chlorite powders in hanging drops.
Analytical biochemistry 2008;373(2):322-9.
2008: Mizushina Yoshiyuki; Takeuchi Toshifumi; Takakusagi Yoichi; Yonezawa Yuko; Mizuno Takeshi; Yanagi Ken-Ichiro; Imamoto Naoko; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Fujita Masatoshi
Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction.
Biochimica et biophysica acta 2008;1780(2):203-13.
2008: Kuriyama Isoko; Mizuno Takeshi; Fukudome Keishi; Kuramochi Kouji; Tsubaki Kazunori; Usui Takeo; Imamoto Naoko; Sakaguchi Kengo; Sugawara Fumio; Yoshida Hiromi; Mizushina Yoshiyuki
Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells.
Molecules (Basel, Switzerland) 2008;13(12):2948-61.
2007: Nakamura Ryoichi; Takeuchi Ryo; Kuramochi Kouji; Mizushina Yoshiyuki; Ishimaru Chisato; Takakusagi Yoichi; Takemura Masaharu; Kobayashi Susumu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Chemical properties of fatty acid derivatives as inhibitors of DNA polymerases.
Organic & biomolecular chemistry 2007;5(24):3912-21.
2007: Takakusagi Yoichi; Takakusagi Kaori; Kuramochi Kouji; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo
Identification of C10 biotinylated camptothecin (CPT-10-B) binding peptides using T7 phage display screen on a QCM device.
Bioorganic & medicinal chemistry 2007;15(24):7590-8.
2007: Sakamoto Aiko; Iwabata Kazuki; Koshiyama Akiyo; Sugawara Hiroko; Yanai Takuro; Kanai Yoshihiro; Takeuchi Ryo; Daikuhara Yoko; Takakusagi Yoichi; Sakaguchi Kengo
Two X family DNA polymerases, lambda and mu, in meiotic tissues of the basidiomycete, Coprinus cinereus.
Chromosoma 2007;116(6):545-56.
2007: Shiomi Toru; Tsunoda Tatsuo; Kawai Akiko; Mizukami Fujio; Sakaguchi Kengo
Formation of cage-like hollow spherical silica via a mesoporous structure by calcination of lysozyme-silica hybrid particles.
Chemical communications (Cambridge, England) 2007;(42):4404-6.
2007: Kanai Yoshihiro; Ishikawa Gen; Takeuchi Ryo; Ruike Tatsushi; Nakamura Ryo-ichi; Ihara Ayumi; Ohashi Tetsuyuki; Takata Kei-ichi; Kimura Seisuke; Sakaguchi Kengo
DmGEN shows a flap endonuclease activity, cleaving the blocked-flap structure and model replication fork.
The FEBS journal 2007;274(15):3914-27.
2007: Sakaguchi Kengo; Koshiyama Akiyo; Iwabata Kazuki
Meiosis and small ubiquitin-related modifier (SUMO)-conjugating enzyme, Ubc9.
The FEBS journal 2007;274(14):3519-31.
2007: Tanaka Toshiaki; Kitamura Hiroshi; Sahara Hiroeki; Imai Akihito; Itoh Yohsuke; Honma Ichiya; Sato Eiji; Kobayashi Ko; Maeda Toshihiro; Takenouchi Mika; Ohta Keisuke; Sugawara Fumio; Sakaguchi Kengo; Ando Asako; Inoko Hidetoshi; Sato Noriyuki; Tsukamoto Taiji
Effects of a new immunosuppressive agent, beta-SQAG9, in swine kidney transplantation.
Transplant immunology 2007;18(1):67-71.
2007: Takeuchi Ryo; Kimura Seisuke; Saotome Ai; Sakaguchi Kengo
Biochemical properties of a plastidial DNA polymerase of rice.
Plant molecular biology 2007;64(5):601-11.
2007: Kimura Seisuke; Saotome Ai; Takeuchi Ryo; Sakaguchi Kengo
[Plastid DNA replication and repair]
Seikagaku. The Journal of Japanese Biochemical Society 2007;79(5):438-41.
2007: Urabe Yoko; Shiomi Toru; Itoh Tetsuji; Kawai Akiko; Tsunoda Tatsuo; Mizukami Fujio; Sakaguchi Kengo
Encapsulation of hemoglobin in mesoporous silica (FSM)-enhanced thermal stability and resistance to denaturants.
Chembiochem : a European journal of chemical biology 2007;8(6):668-74.
2007: Ishimaru Chisato; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Sakaguchi Kengo; Kato Ikuo; Yoshida Hiromi; Mizushina Yoshiyuki
Cholesterol hemisuccinate: a selective inhibitor of family X DNA polymerases.
Biochemical and biophysical research communications 2007;354(2):619-25.
2007: Miura Masahiko; Sakimoto Ippei; Ohta Keisuke; Sugawara Fumio; Sakaguchi Kengo
Sulfoglycolipids as candidate antiangiogenic radiosensitizers.
Anti-cancer drugs 2007;18(1):1-5.
2007: Hamada Fumika N; Koshiyama Akiyo; Namekawa Satoshi H; Ishii Satomi; Iwabata Kazuki; Sugawara Hiroko; Nara Takayuki Y; Sakaguchi Kengo; Sawado Tomoyuki
Proliferating cell nuclear antigen (PCNA) interacts with a meiosis-specific RecA homologues, Lim15/Dmc1, but does not stimulate its strand transfer activity.
Biochemical and biophysical research communications 2007;352(4):836-42.
2007: Iijima Hiroshi; Kasai Nobuyuki; Chiku Hiroyuki; Takeuchi Toshifumi; Kuramochi Kouji; Hanashima Shinya; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structure-activity relationship of a glycolipid, sulfoquinovosyl diacylglycerol, with the DNA binding activity of p53.
International journal of molecular medicine 2007;19(1):41-8.
2007: Maeda Naoki; Kokai Yasuo; Ohtani Seiji; Sahara Hiroeki; Kuriyama Isoko; Kamisuki Shinji; Takahashi Shunya; Sakaguchi Kengo; Sugawara Fumio; Yoshida Hiromi; Sato Noriyuki; Mizushina Yoshiyuki
Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.
Biochemical and biophysical research communications 2007;352(2):390-6.
2006: Ruike Tatsushi; Takeuchi Ryo; Takata Kei-Ichi; Oshige Masahiko; Kasai Nobuyuki; Shimanouchi Kaori; Kanai Yoshihiro; Nakamura Ryoichi; Sugawara Fumio; Sakaguchi Kengo
Characterization of a second proliferating cell nuclear antigen (PCNA2) from Drosophila melanogaster.
The FEBS journal 2006;273(22):5062-73.
2006: Murakami Shizuka; Kamisuki Shinji; Takata Kei-ichi; Kasai Nobuyuki; Kimura Seisuke; Mizushina Yoshiyuki; Ohta Keisuke; Sugawara Fumio; Sakaguchi Kengo
Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta.
Biochemical and biophysical research communications 2006;350(1):7-16.
2006: Koshiyama Akiyo; Hamada Fumika N; Namekawa Satoshi H; Iwabata Kazuki; Sugawara Hiroko; Sakamoto Aiko; Ishizaki Takashi; Sakaguchi Kengo
Sumoylation of a meiosis-specific RecA homolog, Lim15/Dmc1, via interaction with the small ubiquitin-related modifier (SUMO)-conjugating enzyme Ubc9.
The FEBS journal 2006;273(17):4003-12.
2006: Saotome Ai; Kimura Seisuke; Mori Yoko; Uchiyama Yukinobu; Morohashi Kengo; Sakaguchi Kengo
Characterization of four RecQ homologues from rice (Oryza sativa L. cv. Nipponbare).
Biochemical and biophysical research communications 2006;345(4):1283-91.
2006: Iijima Hiroshi; Kasai Nobuyuki; Chiku Hiroyuki; Murakami Shizuka; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
The inhibitory action of long-chain fatty acids on the DNA binding activity of p53.
Lipids 2006;41(6):521-7.
2006: Koga Asami; Ishibashi Toyotaka; Kimura Seisuke; Uchiyama Yukinobu; Sakaguchi Kengo
Characterization of T-DNA insertion mutants and RNAi silenced plants of Arabidopsis thaliana UV-damaged DNA binding protein 2 (AtUV-DDB2).
Plant molecular biology 2006;61(1-2):227-40.
2006: Mizushina Yoshiyuki; Nakanishi Rumi; Kuriyama Isoko; Kamiya Kohei; Satake Toshiko; Shimazaki Noriko; Koiwai Osamu; Uchiyama Yukinobu; Yonezawa Yuko; Takemura Masaharu; Sakaguchi Kengo; Yoshida Hiromi
Beta-sitosterol-3-O-beta-D-glucopyranoside: a eukaryotic DNA polymerase lambda inhibitor.
The Journal of steroid biochemistry and molecular biology 2006;99(2-3):100-7.
2006: Takeuchi Ryo; Ruike Tatsushi; Nakamura Ryo-ichi; Shimanouchi Kaori; Kanai Yoshihiro; Abe Yoko; Ihara Ayumi; Sakaguchi Kengo
Drosophila DNA polymerase zeta interacts with recombination repair protein 1, the Drosophila homologue of human abasic endonuclease 1.
The Journal of biological chemistry 2006;281(17):11577-85.
2006: Takeuchi Toshifumi; Ishidoh Tomomi; Iijima Hiroshi; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Kuramochi Kouji; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Structural relationship of curcumin derivatives binding to the BRCT domain of human DNA polymerase lambda.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(3):223-35.
2006: Sakimoto Ippei; Ohta Keisuke; Yamazaki Takayuki; Ohtani Seiji; Sahara Hiroeki; Sugawara Fumio; Sakaguchi Kengo; Miura Masahiko
Alpha-sulfoquinovosylmonoacylglycerol is a novel potent radiosensitizer targeting tumor angiogenesis.
Cancer research 2006;66(4):2287-95.
2006: Kimura Seisuke; Sakaguchi Kengo
DNA repair in plants.
Chemical reviews 2006;106(2):753-66.
2006: Mizushina Yoshiyuki; Yagita Etsuko; Kuramochi Kouji; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Uchiyama Yukinobu; Yomezawa Yuko; Sugawara Fumio; Kobayashi Susumu; Sakaguchi Kengo; Yoshida Hiromi
5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase.
Archives of biochemistry and biophysics 2006;446(1):69-76.
2006: Ishibashi Toyotaka; Kimura Seisuke; Sakaguchi Kengo
A higher plant has three different types of RPA heterotrimeric complex.
Journal of biochemistry 2006;139(1):99-104.
2006: Shimanouchi Kaori; Takata Kei-Ichi; Yamaguchi Masamitsu; Murakami Shizuka; Ishikawa Gen; Takeuchi Ryo; Kanai Yoshihiro; Ruike Tatsushi; Nakamura Ryoichi; Abe Yoko; Sakaguchi Kengo
Drosophila damaged DNA binding protein 1 contributes to genome stability in somatic cells.
Journal of biochemistry 2006;139(1):51-8.
2006: Mizushina Yoshiyuki; Nakagawa Kiyotaka; Shibata Akira; Awata Yasutoshi; Kuriyama Isoko; Shimazaki Noriko; Koiwai Osamu; Uchiyama Yukinobu; Sakaguchi Kengo; Miyazawa Teruo; Yoshida Hiromi
Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis.
Biochemical and biophysical research communications 2006;339(3):949-55.
2006: Chiku Hiroyuki; Kawai Akiko; Ishibashi Toyotaka; Takehara Masahide; Yanai Takuro; Mizukami Fujio; Sakaguchi Kengo
A novel protein refolding method using a zeolite.
Analytical biochemistry 2006;348(2):307-14.
2006: Ishibashi Toyotaka; Isogai Minako; Kiyohara Hiroyuki; Hosaka Masahiro; Chiku Hiroyuki; Koga Asami; Yamamoto Taichi; Uchiyama Yukinobu; Mori Yoko; Hashimoto Junji; Ausió Juan; Kimura Seisuke; Sakaguchi Kengo
Higher plant RecA-like protein is homologous to RadA.
DNA repair 2006;5(1):80-8.
2005: Matsumoto Kenjiro; Sakai Hideki; Takeuchi Ryo; Tsuchiya Koji; Ohta Keisuke; Sugawara Fumio; Abe Masahiko; Sakaguchi Kengo
Effective form of sulfoquinovosyldiacyglycerol (SQDG) vesicles for DNA polymerase inhibition.
Colloids and surfaces. B, Biointerfaces 2005;46(3):175-81.
2005: Kubota Munehiro; Matsui Masayoshi; Chiku Hiroyuki; Kasashima Nobuyuki; Shimojoh Manabu; Sakaguchi Kengo
Cell adsorption and selective desorption for separation of microbial cells by using chitosan-immobilized silica.
Applied and environmental microbiology 2005;71(12):8895-902.
2005: Mizushina Yoshiyuki; Ishidoh Tomomi; Takeuchi Toshifumi; Shimazaki Noriko; Koiwai Osamu; Kuramochi Kouji; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo; Yoshida Hiromi
Monoacetylcurcumin: a new inhibitor of eukaryotic DNA polymerase lambda and a new ligand for inhibitor-affinity chromatography.
Biochemical and biophysical research communications 2005;337(4):1288-95.
2005: Mizushina Yoshiyuki; Kasai Nobuyuki; Iijima Hiroshi; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
Sulfo-quinovosyl-acyl-glycerol (SQAG), a eukaryotic DNA polymerase inhibitor and anti-cancer agent.
Current medicinal chemistry. Anti-cancer agents 2005;5(6):613-25.
2005: Namekawa Satoshi H; Iwabata Kazuki; Sugawara Hiroko; Hamada Fumika N; Koshiyama Akiyo; Chiku Hiroyuki; Kamada Takashi; Sakaguchi Kengo
Knockdown of LIM15/DMC1 in the mushroom Coprinus cinereus by double-stranded RNA-mediated gene silencing.
Microbiology (Reading, England) 2005;151(Pt 11):3669-78.
2005: Shiomi Toru; Tsunoda Tatsuo; Kawai Akiko; Chiku Hiroyuki; Mizukami Fujio; Sakaguchi Kengo
Synthesis of protein-silica hybrid hollow particles through the combination of protein catalysts and sonochemical treatment.
Chemical communications (Cambridge, England) 2005;(42):5325-7.
2005: Takakusagi Yoichi; Ohta Keisuke; Kuramochi Kouji; Morohashi Kengo; Kobayashi Susumu; Sakaguchi Kengo; Sugawara Fumio
Synthesis of a biotinylated camptothecin derivative and determination of the binding sequence by T7 phage display technology.
Bioorganic & medicinal chemistry letters 2005;15(21):4846-9.
2005: Kasai Nobuyuki; Mizushina Yoshiyuki; Murata Hiroshi; Yamazaki Takayuki; Ohkubo Tadayasu; Sakaguchi Kengo; Sugawara Fumio
Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta.
The FEBS journal 2005;272(17):4349-61.
2005: Shiomi Toru; Matsui Masayoshi; Mizukami Fujio; Sakaguchi Kengo
A method for the molecular imprinting of hemoglobin on silica surfaces using silanes.
Biomaterials 2005;26(27):5564-71.
2005: Mori Yoko; Kimura Seisuke; Saotome Ai; Kasai Nobuyuki; Sakaguchi Norihiro; Uchiyama Yukinobu; Ishibashi Toyotaka; Yamamoto Taichi; Chiku Hiroyuki; Sakaguchi Kengo
Plastid DNA polymerases from higher plants, Arabidopsis thaliana.
Biochemical and biophysical research communications 2005;334(1):43-50.
2005: Ishibashi Toyotaka; Koga Asami; Yamamoto Taichi; Uchiyama Yukinobu; Mori Yoko; Hashimoto Junji; Kimura Seisuke; Sakaguchi Kengo
Two types of replication protein A in seed plants.
The FEBS journal 2005;272(13):3270-81.
2005: Mori Yoko; Yamamoto Taichi; Sakaguchi Norihiro; Ishibashi Toyotaka; Furukawa Tomoyuki; Kadota Yasuhiro; Kuchitsu Kazuyuki; Hashimoto Junji; Kimura Seisuke; Sakaguchi Kengo
Characterization of the origin recognition complex (ORC) from a higher plant, rice (Oryza sativa L.).
Gene 2005;353(1):23-30.
2005: Aoki Satoko; Ohta Keisuke; Yamazaki Takayuki; Sugawara Fumio; Sakaguchi Kengo
Mammalian mitotic centromere-associated kinesin (MCAK): a new molecular target of sulfoquinovosylacylglycerols novel antitumor and immunosuppressive agents.
The FEBS journal 2005;272(9):2132-40.
2005: Mizushina Yoshiyuki; Kuramochi Kouji; Ikawa Hiroshi; Kuriyama Isoko; Shimazaki Noriko; Takemura Masaharu; Oshige Masahiko; Yoshida Hiromi; Koiwai Osamu; Sugawara Fumio; Kobayashi Susumu; Sakaguchi Kengo
Structural analysis of epolactaene derivatives as DNA polymerase inhibitors and anti-inflammatory compounds.
International journal of molecular medicine 2005;15(5):785-93.
2005: Sakaguchi Kengo; Matsui Masayoshi; Mizukami Fujio
Applications of zeolite inorganic composites in biotechnology: current state and perspectives.
Applied microbiology and biotechnology 2005;67(3):306-11.
2005: Yamamoto Taichi; Mori Yoko; Ishibashi Toyotaka; Uchiyama Yukinobu; Ueda Tadamasa; Ando Tsuyu; Hashimoto Junji; Kimura Seisuke; Sakaguchi Kengo
Interaction between proliferating cell nuclear antigen (PCNA) and a DnaJ induced by DNA damage.
Journal of plant research 2005;118(2):91-7.
2005: Kimura Seisuke; Saotome Ai; Uchiyama Yukinobu; Mori Yoko; Tahira Yasue; Sakaguchi Kengo
The expression of the rice (Oryza sativa L.) homologue of Snm1 is induced by DNA damages.
Biochemical and biophysical research communications 2005;329(2):668-72.
2005: Kuriyama Isoko; Asano Naoki; Kato Ikuo; Ikeda Kyoko; Takemura Masaharu; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Dipeptide alcohol-based inhibitors of eukaryotic DNA polymerase alpha.
Bioorganic & medicinal chemistry 2005;13(6):2187-96.
2005: Yonezawa Yuko; Tsuzuki Tsuyoshi; Eitsuka Takahiro; Miyazawa Teruo; Hada Takahiko; Uryu Keisuke; Murakami-Nakai Chikako; Ikawa Hiroshi; Kuriyama Isoko; Takemura Masaharu; Oshige Masahiko; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Inhibitory effect of conjugated eicosapentaenoic acid on human DNA topoisomerases I and II.
Archives of biochemistry and biophysics 2005;435(1):197-206.
2005: Maeda Naoki; Hada Takahiko; Murakami-Nakai Chikako; Kuriyama Isoko; Ichikawa Hideki; Fukumori Yoshinobu; Hiratsuka Junichi; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Effects of DNA polymerase inhibitory and antitumor activities of lipase-hydrolyzed glycolipid fractions from spinach.
The Journal of nutritional biochemistry 2005;16(2):121-8.
2005: Matsumoto Kenjiro; Sakai Hideki; Ohta Keisuke; Kameda Hiroshi; Sugawara Fumio; Abe Masahiko; Sakaguchi Kengo
Monolayer membranes and bilayer vesicles characterized by alpha- and beta-anomer of sulfoquinovosyldiacyglycerol (SQDG).
Chemistry and physics of lipids 2005;133(2):203-14.
2005: Takenouchi M; Sahara H; Yamamoto Y; Matsumoto Y; Imai A; Fujita T; Tamura Y; Takahashi N; Gasa S; Matsumoto K; Ohta K; Sugawara F; Sakaguchi K; Jimbow K; Sato N
Mechanism of the immunosuppressive effect in vivo of novel immunosuppressive drug beta-SQAG9, which inhibits the response of the CD62L+ T-cell subset.
Transplantation proceedings 2005;37(1):139-42.
2005: Iwabata Kazuki; Koshiyama Akiyo; Yamaguchi Taiki; Sugawara Hiroko; Hamada Fumika N; Namekawa Satoshi H; Ishii Satomi; Ishizaki Takashi; Chiku Hiroyuki; Nara Takayuki; Sakaguchi Kengo
DNA topoisomerase II interacts with Lim15/Dmc1 in meiosis.
Nucleic acids research 2005;33(18):5809-18.
2004: Matsumoto Kenjiro; Takenouchi Mika; Ohta Keisuke; Ohta Yumiko; Imura Tomohiro; Oshige Masahiko; Yamamoto Yoshiteru; Sahara Hiroeki; Sakai Hideki; Abe Masahiko; Sugawara Fumio; Sato Noriyuki; Sakaguchi Kengo
Design of vesicles of 1,2-di-O-acyl-3-O-(beta-D-sulfoquinovosyl)-glyceride bearing two stearic acids (beta-SQDG-C18), a novel immunosuppressive drug.
Biochemical pharmacology 2004;68(12):2379-86.
2004: Yamamoto Yoshiteru; Sahara Hiroeki; Takenouchi Mika; Matsumoto Yoshitaka; Imai Akihito; Fujita Tatsuya; Tamura Yasuaki; Takahashi Nobuaki; Gasa Shinsei; Matsumoto Kenjiro; Ohta Keisuke; Sugawara Fumio; Sakaguchi Kengo; Jimbow Kowichi; Sato Noriyuki
Inhibition of CD62L+ T-cell response in vitro via a novel sulfo-glycolipid, beta-SQAG9 liposome that binds to CD62L molecule on the cell surface.
Cellular immunology 2004;232(1-2):105-15.
2004: Namekawa Satoshi H; Hamada Fumika N; Sakaguchi Kengo
[Latest frontiers of meiosis research in Coprinus cinereus]
Seikagaku. The Journal of Japanese Biochemical Society 2004;76(11):1450-4.
2004: Mizushina Yoshiyuki; Tsuzuki Tsuyoshi; Eitsuka Takahiro; Miyazawa Teruo; Kobayashi Kanako; Ikawa Hiroshi; Kuriyama Isoko; Yonezawa Yuko; Takemura Masaharu; Yoshida Hiromi; Sakaguchi Kengo
Inhibitory action of conjugated C18-fatty acids on DNA polymerases and DNA topoisomerases.
Lipids 2004;39(10):977-83.
2004: Takata Kei-ichi; Yoshida Hideki; Yamaguchi Masamitsu; Sakaguchi Kengo
Drosophila damaged DNA-binding protein 1 is an essential factor for development.
Genetics 2004;168(2):855-65.
2004: Kamisuki Shinji; Takahashi Shunya; Mizushina Yoshiyuki; Sakaguchi Kengo; Nakata Tadashi; Sugawara Fumio
Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.
Bioorganic & medicinal chemistry 2004;12(20):5355-9.
2004: Takata Kei-ichi; Shimanouchi Kaori; Yamaguchi Masamitsu; Murakami Shizuka; Ishikawa Gen; Takeuchi Ryo; Kanai Yoshihiro; Ruike Tatsushi; Nakamura Ryou-ichi; Abe Yoko; Sakaguchi Kengo
Damaged DNA binding protein 1 in Drosophila defense reactions.
Biochemical and biophysical research communications 2004;323(3):1024-31.
2004: Tsuruma T; Sahara H; Takenouchi M; Yagihashi A; Iwayama Y; Shima H; Furuhata T; Torigoe T; Hanashima S; Yamazaki T; Sugawara F; Mizushina Y; Ohta K; Sakaguchi K; Sato N; Hirata K
Synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin reduces hepatic ischemia-reperfusion injury in rats.
Transplantation proceedings 2004;36(7):1965-9.
2004: Murakami-Nakai Chikako; Maeda Naoki; Yonezawa Yuko; Kuriyama Isoko; Kamisuki Shinji; Takahashi Shunya; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression.
Biochimica et biophysica acta 2004;1674(2):193-9.
2004: Oshige Masahiko; Kuramochi Kouji; Ohta Keisuke; Ogawa Akitsu; Kuriyama Hiroki; Sugawara Fumio; Kobayashi Susumu; Sakaguchi Kengo
Molecular design of cholesterols as inhibitors of DNA polymerase alpha.
Journal of medicinal chemistry 2004;47(20):4971-4.
2004: Takeuchi Ryo; Oshige Masahiko; Uchida Makiyo; Ishikawa Gen; Takata Kei-ichi; Shimanouchi Kaori; Kanai Yoshihiro; Ruike Tatsushi; Morioka Hiroshi; Sakaguchi Kengo
Purification of Drosophila DNA polymerase zeta by REV1 protein-affinity chromatography.
The Biochemical journal 2004;382(Pt 2):535-43.
2004: Mizushina Yoshiyuki; Kasai Nobuyuki; Miura Katsumi; Hanashima Shinya; Takemura Masaharu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Structural relationship of lithocholic acid derivatives binding to the N-terminal 8-kDa domain of DNA polymerase beta.
Biochemistry 2004;43(33):10669-77.
2004: Uchiyama Yukinobu; Kimura Seisuke; Yamamoto Taichi; Ishibashi Toyotaka; Sakaguchi Kengo
Plant DNA polymerase lambda, a DNA repair enzyme that functions in plant meristematic and meiotic tissues.
European journal of biochemistry / FEBS 2004;271(13):2799-807.
2004: Oshige Masahiko; Takeuchi Ryo; Ruike Tatsuji; Kuroda Kazufumi; Sakaguchi Kengo
Subunit protein-affinity isolation of Drosophila DNA polymerase catalytic subunit.
Protein expression and purification 2004;35(2):248-56.
2004: Oshige Masahiko; Takenouchi Mika; Kato Yasutaro; Kamisuki Sinji; Takeuchi Toshifumi; Kuramochi Kouji; Shiina Isamu; Suenaga Yoshihito; Kawakita Yo-ichi; Kuroda Kazufumi; Sato Noriyuki; Kobayashi Susumu; Sugawara Fumio; Sakaguchi Kengo
Taxol derivatives are selective inhibitors of DNA polymerase alpha.
Bioorganic & medicinal chemistry 2004;12(10):2597-601.
2004: Kuramochi Kouji; Mizushina Yoshiyuki; Nagata Seigo; Sugawara Fumio; Sakaguchi Kengo; Kobayashi Susumu
Structure-activity relationships of epolactaene analogs as DNA polymerases inhibitors.
Bioorganic & medicinal chemistry 2004;12(9):1983-9.
2004: Yamaguchi Taiki; Namekawa Satoshi H; Hamada Fumika N; Kasai Nobuyuki; Nara Takayuki; Watanabe Kei; Iwabata Kazuki; Ishizaki Takashi; Ishii Satomi; Koshiyama Akiyo; Inagaki Sachiyo; Kimura Seisuke; Sakaguchi Kengo
Expression of flap endonuclease-1 during meiosis in a basidiomycete, Coprinus cinereus.
Fungal genetics and biology : FG & B 2004;41(5):493-500.
2004: Mizushina Yoshiyuki; Akihisa Toshihiro; Ukiya Motohiko; Murakami Chikako; Kuriyama Isoko; Xu Xianai; Yoshida Hiromi; Sakaguchi Kengo
A novel DNA topoisomerase inhibitor: dehydroebriconic acid, one of the lanostane-type triterpene acids from Poria cocos.
Cancer science 2004;95(4):354-60.
2004: Saito Fumiyo; Takeuchi Ryo; Kamino Tomoyuki; Kuramochi Kouji; Sugawara Fumio; Sakaguchi Kengo; Kobayashi Susumu
Structure-activity relationships of untenone A and its derivatives for inhibition of DNA polymerases.
Bioorganic & medicinal chemistry letters 2004;14(8):1975-7.
2004: Kuriyama Isoko; Asano Naoki; Kato Ikuo; Oshige Masahiko; Sugino Akio; Kadota Yasuhiro; Kuchitsu Kazuyuki; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
L-Homoserylaminoethanol, a novel dipeptide alcohol inhibitor of eukaryotic DNA polymerase from a plant cultured cells, Nicotina tabacum L.
Bioorganic & medicinal chemistry 2004;12(5):957-62.
2004: Yamamoto Taichi; Mori Yoko; Ishibashi Toyotaka; Uchiyama Yukinobu; Sakaguchi Norihiro; Furukawa Tomoyuki; Hashimoto Junji; Kimura Seisuke; Sakaguchi Kengo
Characterization of Rad6 from a higher plant, rice (Oryza sativa L.) and its interaction with Sgt1, a subunit of the SCF ubiquitin ligase complex.
Biochemical and biophysical research communications 2004;314(2):434-9.
2004: Yamamoto Taichi; Kimura Seisuke; Mori Yoko; Oka Masayoshi; Ishibashi Toyotaka; Yanagawa Yuki; Nara Takayuki; Nakagawa Hiroki; Hashimoto Junji; Sakaguchi Kengo
Degradation of proliferating cell nuclear antigen by 26S proteasome in rice (Oryza sativa L.).
Planta 2004;218(4):640-6.
2004: Ishikawa Gen; Kanai Yoshihiro; Takata Kei-ichi; Takeuchi Ryo; Shimanouchi Kaori; Ruike Tatsushi; Furukawa Tomoyuki; Kimura Seisuke; Sakaguchi Kengo
DmGEN, a novel RAD2 family endo-exonuclease from Drosophila melanogaster.
Nucleic acids research 2004;32(21):6251-9.
2004: Kimura Seisuke; Tahira Yasue; Ishibashi Toyotaka; Mori Yoko; Mori Toshio; Hashimoto Junji; Sakaguchi Kengo
DNA repair in higher plants; photoreactivation is the major DNA repair pathway in non-proliferating cells while excision repair (nucleotide excision repair and base excision repair) is active in proliferating cells.
Nucleic acids research 2004;32(9):2760-7.
2003: Mizushina Yoshiyuki; Xu Xianai; Matsubara Kiminori; Murakami Chikako; Kuriyama Isoko; Oshige Masahiko; Takemura Masaharu; Kato Norihisa; Yoshida Hiromi; Sakaguchi Kengo
Pyridoxal 5'-phosphate is a selective inhibitor in vivo of DNA polymerase alpha and epsilon.
Biochemical and biophysical research communications 2003;312(4):1025-32.
2003: Mizushina Yoshiyuki; Hirota Mitsuru; Murakami Chikako; Ishidoh Tomomi; Kamisuki Shinji; Shimazaki Noriko; Takemura Masaharu; Perpelescu Marinela; Suzuki Motoshi; Yoshida Hiromi; Sugawara Fumio; Koiwai Osamu; Sakaguchi Kengo
Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.
Biochemical pharmacology 2003;66(10):1935-44.
2003: Mizushina Yoshiyuki; Maeda Naoki; Kawasaki Miho; Ichikawa Hideki; Murakami Chikako; Takemura Masaharu; Xu Xianai; Sugawara Fumio; Fukumori Yoshinobu; Yoshida Hiromi; Sakaguchi Kengo
Inhibitory action of emulsified sulfoquinovosyl acylglycerol on mammalian DNA polymerases.
Lipids 2003;38(10):1065-74.
2003: Kimura Seisuke; Furukawa Tomoyuki; Kasai Nobuyuki; Mori Yoko; Kitamoto Hiroko K; Sugawara Fumio; Hashimoto Junji; Sakaguchi Kengo
Functional characterization of two flap endonuclease-1 homologues in rice.
Gene 2003;314():63-71.
2003: Murakami Chikako; Takemura Masaharu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Analysis of cell cycle regulation by 1-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride (SQMG), an inhibitor of eukaryotic DNA polymerases.
Biochemical pharmacology 2003;66(4):541-50.
2003: Namekawa Satoshi; Ichijima Yosuke; Hamada Fumika; Kasai Nobuyuki; Iwabata Kazuki; Nara Takayuki; Teraoka Hirobumi; Sugawara Fumio; Sakaguchi Kengo
DNA ligase IV from a basidiomycete, Coprinus cinereus, and its expression during meiosis.
Microbiology (Reading, England) 2003;149(Pt 8):2119-28.
2003: Mizushina Yoshiyuki; Xu Xianai; Murakami Chikako; Okano Toshio; Takemura Masaharu; Yoshida Hiromi; Sakaguchi Kengo
Selective inhibition of mammalian DNA polymerase alpha by vitamin D2 and D3.
Journal of pharmacological sciences 2003;92(3):283-90.
2003: Chiku Hiroyuki; Matsui Masayoshi; Murakami Shizuka; Kiyozumi Yoshimichi; Mizukami Fujio; Sakaguchi Kengo
Zeolites as new chromatographic carriers for proteins--easy recovery of proteins adsorbed on zeolites by polyethylene glycol.
Analytical biochemistry 2003;318(1):80-5.
2003: Yamamoto Taichi; Kimura Seisuke; Mori Yoko; Uchiyama Yukinobu; Ishibashi Toyotaka; Hashimoto Junji; Sakaguchi Kengo
Interaction between proliferating cell nuclear antigen and JUN-activation-domain-binding protein 1 in the meristem of rice, Oryza sativa L.
Planta 2003;217(2):175-83.
2003: Namekawa Satoshi; Hamada Fumika; Ishii Satomi; Ichijima Yosuke; Yamaguchi Taiki; Nara Takayuki; Kimura Seisuke; Ishizaki Takashi; Iwabata Kazuki; Koshiyama Akiyo; Teraoka Hirobumi; Sakaguchi Kengo
Coprinus cinereus DNA ligase I during meiotic development.
Biochimica et biophysica acta 2003;1627(1):47-55.
2003: Mizushina Yoshiyuki; Murakami Chikako; Yogi Kentaro; Ueda Katsuhiro; Ishidoh Tomomi; Takemura Masaharu; Perpelescu Marinela; Suzuki Motoshi; Oshige Masahiko; Yamaguchi Toyofumi; Saneyoshi Mineo; Yoshida Hiromi; Sakaguchi Kengo
Kohamaic acid A, a novel sesterterpenic acid, inhibits activities of DNA polymerases from deuterostomes.
Biochimica et biophysica acta 2003;1648(1-2):55-61.
2003: Namekawa Satoshi; Hamada Fumika; Sawado Tomoyuki; Ishii Satomi; Nara Takayuki; Ishizaki Takashi; Ohuchi Takashi; Arai Takao; Sakaguchi Kengo
Dissociation of DNA polymerase alpha-primase complex during meiosis in Coprinus cinereus.
European journal of biochemistry / FEBS 2003;270(10):2137-46.
2003: Mizushina Yoshiyuki; Ikuta Akira; Endoh Kenji; Oshige Masahiko; Kasai Nobuyuki; Kamiya Kohei; Satake Toshiko; Takazawa Hiroshi; Morita Hiromasa; Tomiyasu Hiroaki; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Inhibition of DNA polymerases and DNA topoisomerase II by triterpenes produced by plant callus.
Biochemical and biophysical research communications 2003;305(2):365-73.
2003: Mizushina Yoshiyuki; Murakami Chikako; Takikawa Hirosato; Kasai Nobuyuki; Xu Xianai; Mori Kenji; Oshige Masahiko; Yamaguchi Toyofumi; Saneyoshi Mineo; Shimazaki Noriko; Koiwai Osamu; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Molecular action mode of Hippospongic acid A, an inhibitor of gastrulation of starfish embryos.
Journal of biochemistry 2003;133(4):541-52.
2003: Ishibashi Toyotaka; Kimura Seisuke; Yamamoto Taichi; Furukawa Tomoyuki; Takata Kei-ichi; Uchiyama Yukinobu; Hashimoto Junji; Sakaguchi Kengo
Rice UV-damaged DNA binding protein homologues are most abundant in proliferating tissues.
Gene 2003;308():79-87.
2003: Mizushina Yoshiyuki; Xu Xianai; Asano Naoki; Kasai Nobuyuki; Kato Atsushi; Takemura Masaharu; Asahara Hitomi; Linn Stuart; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
The inhibitory action of pyrrolidine alkaloid, 1,4-dideoxy-1,4-imino-D-ribitol, on eukaryotic DNA polymerases.
Biochemical and biophysical research communications 2003;304(1):78-85.
2003: Mizushina Yoshiyuki; Ishidoh Tomomi; Kamisuki Shinji; Nakazawa Satoshi; Takemura Masaharu; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
Flavonoid glycoside: a new inhibitor of eukaryotic DNA polymerase alpha and a new carrier for inhibitor-affinity chromatography.
Biochemical and biophysical research communications 2003;301(2):480-7.
2003: Mizushina Yoshiyuki; Xu Xianai; Asahara Hitomi; Takeuchi Ryo; Oshige Masahiko; Shimazaki Noriko; Takemura Masaharu; Yamaguchi Toyofumi; Kuroda Kazufumi; Linn Stuart; Yoshida Hiromi; Koiwai Osamu; Saneyoshi Mineo; Sugawara Fumio; Sakaguchi Kengo
A sulphoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor.
The Biochemical journal 2003;370(Pt 1):299-305.
2003: Furukawa Tomoyuki; Kimura Seisuke; Ishibashi Toyotaka; Mori Yoko; Hashimoto Junji; Sakaguchi Kengo
OsSEND-1: a new RAD2 nuclease family member in higher plants.
Plant molecular biology 2003;51(1):59-70.
2003: Murakami Chikako; Yamazaki Takayuki; Hanashima Shinya; Takahashi Shunya; Takemura Masaharu; Yoshida Shonen; Ohta Keisuke; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid.
Biochimica et biophysica acta 2003;1645(1):72-80.
2003: Murakami Chikako; Kumagai Taeko; Hada Takahiko; Kanekazu Ui; Nakazawa Satoshi; Kamisuki Shinji; Maeda Naoki; Xu Xianai; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Effects of glycolipids from spinach on mammalian DNA polymerases.
Biochemical pharmacology 2003;65(2):259-67.
2003: Takata Kei-ichi; Inoue Yoshihiro H; Hirose Fumiko; Murakami Shizuka; Shimanouchi Kaori; Sakimoto Ippei; Sakaguchi Kengo
Spatio-temporal expression of Drosophila mitochondrial transcription factor A during development.
Cell biology international 2003;27(4):361-74.
2002: Mizushina Yoshiyuki; Kamisuki Shinji; Kasai Nobuyuki; Ishidoh Tomomi; Shimazaki Noriko; Takemura Masaharu; Asahara Hitomi; Linn Stuart; Yoshida Shonen; Koiwai Osamu; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
Petasiphenol: a DNA polymerase lambda inhibitor.
Biochemistry 2002;41(49):14463-71.
2002: Kasai Nobuyuki; Mizushina Yoshiyuki; Sugawara Fumio; Sakaguchi Kengo
Three-dimensional structural model analysis of the binding site of an inhibitor, nervonic acid, of both DNA polymerase beta and HIV-1 reverse transcriptase.
Journal of biochemistry 2002;132(5):819-28.
2002: Takata Kei-ichi; Ishikawa Gen; Hirose Fumiko; Sakaguchi Kengo
Drosophila damage-specific DNA-binding protein 1 (D-DDB1) is controlled by the DRE/DREF system.
Nucleic acids research 2002;30(17):3795-808.
2002: Uchiyama Yukinobu; Hatanaka Masami; Kimura Seisuke; Ishibashi Toyotaka; Ueda Tadamasa; Sakakibara Yoshikiyo; Matsumoto Takashi; Furukawa Tomoyuki; Hashimoto Junji; Sakaguchi Kengo
Characterization of DNA polymerase delta from a higher plant, rice (Oryza sativa L.).
Gene 2002;295(1):19-26.
2002: Matsumoto Yoshitaka; Sahara Hiroeki; Fujita Tatsuya; Shimozawa Kumiko; Takenouchi Mika; Torigoe Toshihiko; Hanashima Shinya; Yamazaki Takeyuki; Takahashi Shunya; Sugawara Fumio; Mizushina Yoshiyuki; Ohta Keisuke; Takahashi Nobuaki; Gasa Shinsei; Jimbow Kouichi; Sakaguchi Kengo; Sato Noriyuki
An immunosuppressive effect by synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin.
Transplantation 2002;74(2):261-7.
2002: Murakami Chikako; Yamazaki Takayuki; Hanashima Shinya; Takahashi Shunya; Ohta Keisuke; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Structure-function relationship of synthetic sulfoquinovosyl-acylglycerols as mammalian DNA polymerase inhibitors.
Archives of biochemistry and biophysics 2002;403(2):229-36.
2002: Murakami Chikako; Ishijima Kiyomi; Hirota Mitsuru; Sakaguchi Kengo; Yoshida Hiromi; Mizushina Yoshiyuki
Novel anti-inflammatory compounds from Rubus sieboldii, triterpenoids, are inhibitors of mammalian DNA polymerases.
Biochimica et biophysica acta 2002;1596(2):193-200.
2002: Kimura Seisuke; Uchiyama Yukinobu; Kasai Nobuyuki; Namekawa Satoshi; Saotome Ai; Ueda Tadamasa; Ando Tsuyu; Ishibashi Toyotaka; Oshige Masahiko; Furukawa Tomoyuki; Yamamoto Taichi; Hashimoto Junji; Sakaguchi Kengo
A novel DNA polymerase homologous to Escherichia coli DNA polymerase I from a higher plant, rice (Oryza sativa L.).
Nucleic acids research 2002;30(7):1585-92.
2002: Sakaguchi Kengo; Sugawara Fumio; Mizushina Yoshiyuki
[Inhibitors of eukaryotic DNA polymerases]
Seikagaku. The Journal of Japanese Biochemical Society 2002;74(3):244-51.
2002: Murakami Chikako; Takemura Masaharu; Sugiyama Yuichi; Kamisuki Shinji; Asahara Hitomi; Kawasaki Miho; Ishidoh Tomomi; Linn Stuart; Yoshida Shonen; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo; Mizushina Yoshiyuki
Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases.
Biochimica et biophysica acta 2002;1574(1):85-92.
2002: Kamisuki Shinji; Murakami Chikako; Ohta Keisuke; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo; Mizushina Yoshiyuki
Actions of derivatives of dehydroaltenusin, a new mammalian DNA polymerase alpha-specific inhibitor.
Biochemical pharmacology 2002;63(3):421-7.
2002: Mizushina Yoshiyuki; Murakami Chikako; Ohta Keisuke; Takikawa Hirosato; Mori Kenji; Yoshida Hiromi; Sugawara Fumio; Sakaguchi Kengo
Selective inhibition of the activities of both eukaryotic DNA polymerases and DNA topoisomerases by elenic acid.
Biochemical pharmacology 2002;63(3):399-407.
2002: Ishizaki Takashi; Tosaka Aki; Nara Takayuki; Aoshima Narumichi; Namekawa Satoshi; Watanabe Kei; Hamada Fumika; Omori Akira; Sakaguchi Kengo
Leucine aminopeptidase during meiotic development.
European journal of biochemistry / FEBS 2002;269(3):826-32.
2002: Watanabe Madoka; Hanashima Shinya; Mizushina Yoshiyuki; Yoshida Hiromi; Oshige Masahiko; Sakaguchi Kengo; Sugawara Fumio
Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases alpha and beta.
Bioorganic & medicinal chemistry letters 2002;12(3):287-90.
2002: Sahara Hiroeki; Hanashima Shinya; Yamazaki Takayuki; Takahashi Shunya; Sugawara Fumio; Ohtani Seiji; Ishikawa Masako; Mizushina Yoshiyuki; Ohta Keisuke; Shimozawa Kumiko; Gasa Shinsei; Jimbow Kouichi; Sakaguchi Kengo; Sato Noriyuki; Takahashi Nobuaki
Anti-tumor effect of chemically synthesized sulfolipids based on sea urchin's natural sulfonoquinovosylmonoacylglycerols.
Japanese journal of cancer research : Gann 2002;93(1):85-92.
2002: Hamada Fumika; Namekawa Satoshi; Kasai Nobuyuki; Nara Takayuki; Kimura Seisuke; Sugawara Fumio; Sakaguchi Kengo
Proliferating cell nuclear antigen from a basidiomycete, Coprinus cinereus. Alternative truncation and expression in meiosis.
European journal of biochemistry / FEBS 2002;269(1):164-74.
2002: Mizushina Yoshiyuki; Kamisuki Shinji; Kasai Nobuyuki; Shimazaki Noriko; Takemura Masaharu; Asahara Hitomi; Linn Stuart; Yoshida Shonen; Matsukage Akio; Koiwai Osamu; Sugawara Fumio; Yoshida Hiromi; Sakaguchi Kengo
A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase beta and lambda.
The Journal of biological chemistry 2002;277(1):630-8.
2001: Kimura S; Suzuki T; Yanagawa Y; Yamamoto T; Nakagawa H; Tanaka I; Hashimoto J; Sakaguchi K
Characterization of plant proliferating cell nuclear antigen (PCNA) and flap endonuclease-1 (FEN-1), and their distribution in mitotic and meiotic cell cycles.
The Plant journal : for cell and molecular biology 2001;28(6):643-53.
2001: Ohta K; Mizushina Y; Yamazaki T; Hanashima S; Sugawara F; Sakaguchi K
Specific interaction between an oligosaccharide on the tumor cell surface and the novel antitumor agents, sulfoquinovosylacylglycerols.
Biochemical and biophysical research communications 2001;288(4):893-900.
2001: Mizushina Y; Kasai N; Sugawara F; Iida A; Yoshida H; Sakaguchi K
Three-dimensional structural model analysis of the binding site of lithocholic acid, an inhibitor of DNA polymerase beta and DNA topoisomerase II.
Journal of biochemistry 2001;130(5):657-64.
2001: Takata K; Yoshida H; Hirose F; Yamaguchi M; Kai M; Oshige M; Sakimoto I; Koiwai O; Sakaguchi K
Drosophila mitochondrial transcription factor A: characterization of its cDNA and expression pattern during development.
Biochemical and biophysical research communications 2001;287(2):474-83.
2001: Ishibashi T; Kimura S; Furukawa T; Hatanaka M; Hashimoto J; Sakaguchi K
Two types of replication protein A 70 kDa subunit in rice, Oryza sativa: molecular cloning, characterization, and cellular & tissue distribution.
Gene 2001;272(1-2):335-43.
2001: Nara T; Hamada F; Namekawa S; Sakaguchi K
Strand exchange reaction in vitro and DNA-dependent ATPase activity of recombinant LIM15/DMC1 and RAD51 proteins from Coprinus cinereus.
Biochemical and biophysical research communications 2001;285(1):92-7.
2001: Hanashima S; Mizushina Y; Yamazaki T; Ohta K; Takahashi S; Sahara H; Sakaguchi K; Sugawar F
Synthesis of sulfoquinovosylacylglycerols, inhibitors of eukaryotic DNA polymerase alpha and beta.
Bioorganic & medicinal chemistry 2001;9(2):367-76.
2000: Mizushina Y; Sugawara F; Iida A; Sakaguchi K
Structural homology between DNA binding sites of DNA polymerase beta and DNA topoisomerase II.
Journal of molecular biology 2000;304(3):385-95.
2000: Matsumoto Y; Sahara H; Fujita T; Hanashima S; Yamazaki T; Takahashi S; Sugawara F; Mizushina Y; Ohta K; Takahashi N; Jimbow K; Sakaguchi K; Sato N
A novel immunosuppressive agent, SQDG, derived from sea urchin.
Transplantation proceedings 2000;32(7):2051-3.
2000: Oshige M; Yoshida H; Hirose F; Takata K I; Inoue Y; Aoyagi N; Yamaguchi M; Koiwai O; Matsukage A; Sakaguchi K
Molecular cloning and expression during development of the Drosophila gene for the catalytic subunit of DNA polymerase epsilon.
Gene 2000;256(1-2):93-100.
2000: Hanashima S; Mizushina Y; Ohta K; Yamazaki T; Sugawara F; Sakaguchi K
Structure-activity relationship of a novel group of mammalian DNA polymerase inhibitors, synthetic sulfoquinovosylacylglycerols.
Japanese journal of cancer research : Gann 2000;91(10):1073-83.
2000: Mizushina Y; Ueno T; Oda M; Yamaguchi T; Saneyoshi M; Sakaguchi K
The biochemical mode of inhibition of DNA polymerase beta by alpha-rubromycin.
Biochimica et biophysica acta 2000;1523(2-3):172-81.
2000: Mizushina Y; Ohkubo T; Sugawara F; Sakaguchi K
Structure of lithocholic acid binding to the N-terminal 8-kDa domain of DNA polymerase beta.
Biochemistry 2000;39(41):12606-13.
2000: Mizushina Y; Kamisuki S; Mizuno T; Takemura M; Asahara H; Linn S; Yamaguchi T; Matsukage A; Hanaoka F; Yoshida S; Saneyoshi M; Sugawara F; Sakaguchi K
Dehydroaltenusin, a mammalian DNA polymerase alpha inhibitor.
The Journal of biological chemistry 2000;275(43):33957-61.
2000: Mizushina Y; Iida A; Ohta K; Sugawara F; Sakaguchi K
Novel triterpenoids inhibit both DNA polymerase and DNA topoisomerase.
The Biochemical journal 2000;350 Pt 3():757-63.
2000: Nara T; Yamamoto T; Sakaguchi K
Characterization of interaction of C- and N-terminal domains in LIM15/DMC1 and RAD51 from a basidiomycetes, Coprinus cinereus.
Biochemical and biophysical research communications 2000;275(1):97-102.
2000: Mizushina Y; Sagisaka M; Sakaib H; Abeb M; Sakaguchi K
Mode analysis of binding of fatty acids to mammalian DNA polymerases.
Biochimica et biophysica acta 2000;1486(2-3):211-8.
2000: Mizushina Y; Kobayashi S; Kuramochi K; Nagata S; Sugawara F; Sakaguchi K
Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, selectively inhibits the activities of mammalian DNA polymerases and human DNA topoisomerase II.
Biochemical and biophysical research communications 2000;273(2):784-8.
2000: Mizushina Y; Miyazaki S; Ohta K; Hirota M; Sakaguchi K
Novel anti-inflammatory compounds from Myrsine seguinii, terpeno-benzoic acids, are inhibitors of mammalian DNA polymerases.
Biochimica et biophysica acta 2000;1475(1):1-4.
2000: Ohta K; Hanashima S; Mizushina Y; Yamazaki T; Saneyoshi M; Sugawara F; Sakaguchi K
Studies on a novel DNA polymerase inhibitor group, synthetic sulfoquinovosylacylglycerols: inhibitory action on cell proliferation.
Mutation research 2000;467(2):139-52.
2000: Kimura S; Ueda T; Hatanaka M; Takenouchi M; Hashimoto J; Sakaguchi K
Plant homologue of flap endonuclease-1: molecular cloning, characterization, and evidence of expression in meristematic tissues.
Plant molecular biology 2000;42(3):415-27.
1999: Nara T; Saka T; Sawado T; Takase H; Ito Y; Hotta Y; Sakaguchi K
Isolation of a LIM15/DMC1 homolog from the basidiomycete Coprinus cinereus and its expression in relation to meiotic chromosome pairing.
Molecular & general genetics : MGG 1999;262(4-5):781-9.
1999: Mizushina Y; Takahashi N; Hanashima L; Koshino H; Esumi Y; Uzawa J; Sugawara F; Sakaguchi K
Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum.
Bioorganic & medicinal chemistry 1999;7(9):2047-52.
1999: Mizushina Y; Ohkubo T; Date T; Yamaguchi T; Saneyoshi M; Sugawara F; Sakaguchi K
Mode analysis of a fatty acid molecule binding to the N-terminal 8-kDa domain of DNA polymerase beta. A 1:1 complex and binding surface.
The Journal of biological chemistry 1999;274(36):25599-607.
1999: Mizushina Y; Takahashi N; Ogawa A; Tsurugaya K; Koshino H; Takemura M; Yoshida S; Matsukage A; Sugawara F; Sakaguchi K
The cyanogenic glucoside, prunasin (D-mandelonitrile-beta-D-glucoside), is a novel inhibitor of DNA polymerase beta.
Journal of biochemistry 1999;126(2):430-6.
1999: Oshige M; Aoyagi N; Harris P V; Burtis K C; Sakaguchi K
A new DNA polymerase species from Drosophila melanogaster: a probable mus308 gene product.
Mutation research 1999;433(3):183-92.
1999: Ohta K; Mizushina Y; Hirata N; Takemura M; Sugawara F; Matsukage A; Yoshida S; Sakaguchi K
Action of a new mammalian DNA polymerase inhibitor, sulfoquinovosyldiacylglycerol.
Biological & pharmaceutical bulletin 1999;22(2):111-6.
1998: Sawado T; Yamaguchi M; Nishimoto Y; Ohno K; Sakaguchi K; Matsukage A
dE2F2, a novel E2F-family transcription factor in Drosophila melanogaster.
Biochemical and biophysical research communications 1998;251(2):409-15.
1998: Sawado T; Hirose F; Takahashi Y; Sasaki T; Shinomiya T; Sakaguchi K; Matsukage A; Yamaguchi M
The DNA replication-related element (DRE)/DRE-binding factor system is a transcriptional regulator of the Drosophila E2F gene.
The Journal of biological chemistry 1998;273(40):26042-51.
1998: Mizushina Y; Ueno T; Goto Y; Isobe Y; Sako M; Fujita T; Hirota K; Hayashi H; Sakaguchi K
Carboxyflavins, novel inhibitors of Taq DNA polymerase.
International journal of molecular medicine 1998;2(3):283-6.
1998: Togashi H; Mizushina Y; Takemura M; Sugawara F; Koshino H; Esumi Y; Uzawa J; Kumagai H; Matsukage A; Yoshida S; Sakaguchi K
4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-alpha activity and the growth of human cancer cells in vitro.
Biochemical pharmacology 1998;56(5):583-90.
1998: Mizushina Y; Hanashima L; Yamaguchi T; Takemura M; Sugawara F; Saneyoshi M; Matsukage A; Yoshida S; Sakaguchi K
A mushroom fruiting body-inducing substance inhibits activities of replicative DNA polymerases.
Biochemical and biophysical research communications 1998;249(1):17-22.
1998: Seto H; Hatanaka M; Kimura S; Oshige M; Tsuya Y; Mizushina Y; Sawado T; Aoyagi N; Matsumoto T; Hashimoto J; Sakaguchi K
Purification and characterization of a 100 kDa DNA polymerase from cauliflower inflorescence.
The Biochemical journal 1998;332 ( Pt 2)():557-63.
1998: Mizushina Y; Watanabe I; Togashi H; Hanashima L; Takemura M; Ohta K; Sugawara F; Koshino H; Esumi Y; Uzawa J; Matsukage A; Yoshida S; Sakaguchi K
An ergosterol peroxide, a natural product that selectively enhances the inhibitory effect of linoleic acid on DNA polymerase beta.
Biological & pharmaceutical bulletin 1998;21(5):444-8.
1998: Mizushina Y; Matsukage A; Sakaguchi K
The biochemical inhibition mode of bredinin-5'-monophosphate on DNA polymerase beta.
Biochimica et biophysica acta 1998;1403(1):5-11.
1998: Ohta K; Mizushina Y; Hirata N; Takemura M; Sugawara F; Matsukage A; Yoshida S; Sakaguchi K
Sulfoquinovosyldiacylglycerol, KM043, a new potent inhibitor of eukaryotic DNA polymerases and HIV-reverse transcriptase type 1 from a marine red alga, Gigartina tenella.
Chemical & pharmaceutical bulletin 1998;46(4):684-6.
1998: Kai M; Todo T; Wada M; Ryo H; Masutani C; Kobayashi H; Morioka H; Ohtsuka E; Hanaoka F; Sakaguchi K
A new Drosophila ultraviolet light-damaged DNA recognition endonuclease that selectively nicks a (6-4) photoproduct site.
Biochimica et biophysica acta 1998;1397(2):180-8.
1998: Mizushina Y; Tanaka N; Kitamura A; Tamai K; Ikeda M; Takemura M; Sugawara F; Arai T; Matsukage A; Yoshida S; Sakaguchi K
The inhibitory effect of novel triterpenoid compounds, fomitellic acids, on DNA polymerase beta.
The Biochemical journal 1998;330 ( Pt 3)():1325-32.
1998: Mizushina Y; Watanabe I; Ohta K; Takemura M; Sahara H; Takahashi N; Gasa S; Sugawara F; Matsukage A; Yoshida S; Sakaguchi K
Studies on inhibitors of mammalian DNA polymerase alpha and beta: sulfolipids from a pteridophyte, Athyrium niponicum.
Biochemical pharmacology 1998;55(4):537-41.
1998: Tanaka N; Kitamura A; Mizushina Y; Sugawara F; Sakaguchi K
Fomitellic acids, triterpenoid inhibitors of eukaryotic DNA polymerases from a basidiomycete, Fomitella fraxinea.
Journal of natural products 1998;61(2):193-7.
1998: Horie T; Mizushina Y; Takemura M; Sugawara F; Matsukage A; Yoshida S; Sakaguchi K
A 5'-monophosphate form of bredinin selectively inhibits the activities of mammalian DNA polymerases in vitro.
International journal of molecular medicine 1998;1(1):83-90.
1997: Kimura S; Kai M; Kobayashi H; Suzuki A; Morioka H; Otsuka E; Sakaguchi K
A structure-specific endonuclease from cauliflower (Brassica oleracea var. botrytis) inflorescence.
Nucleic acids research 1997;25(24):4970-6.
1997: Kitamura A; Kouroku Y; Onoue M; Kimura S; Takenouchi M; Sakaguchi K
A new meiotic endonuclease from Coprinus meiocytes.
Biochimica et biophysica acta 1997;1342(2):205-16.
1997: Mizushina Y; Yoshida S; Matsukage A; Sakaguchi K
The inhibitory action of fatty acids on DNA polymerase beta.
Biochimica et biophysica acta 1997;1336(3):509-21.
1997: Sawado T; Sakaguchi K
A DNA polymerase alpha catalytic subunit is purified independently from the tissues at meiotic prometaphase I of a basidiomycete, Coprinus cinereus.
Biochemical and biophysical research communications 1997;232(2):454-60.
1997: Aoyagi N; Oshige M; Hirose F; Kuroda K; Matsukage A; Sakaguchi K
DNA polymerase epsilon from Drosophila melanogaster.
Biochemical and biophysical research communications 1997;230(2):297-301.
1996: Ohno K; Hirose F; Sakaguchi K; Nishida Y; Matsukage A
Transcriptional regulation of the Drosophila CycA gene by the DNA replication-related element (DRE) and DRE binding factor (DREF).
Nucleic acids research 1996;24(20):3942-6.
1996: Mizushina Y; Tanaka N; Yagi H; Kurosawa T; Onoue M; Seto H; Horie T; Aoyagi N; Yamaoka M; Matsukage A; Yoshida S; Sakaguchi K
Fatty acids selectively inhibit eukaryotic DNA polymerase activities in vitro.
Biochimica et biophysica acta 1996;1308(3):256-62.
1996: Mizushina Y; Yagi H; Tanaka N; Kurosawa T; Seto H; Katsumi K; Onoue M; Ishida H; Iseki A; Nara T; Morohashi K; Horie T; Onomura Y; Narusawa M; Aoyagi N; Takami K; Yamaoka M; Inoue Y; Matsukage A; Yoshida S; Sakaguchi K
Screening of inhibitor of eukaryotic DNA polymerases produced by microorganisms.
The Journal of antibiotics 1996;49(5):491-2.
1996: Matsuda S; Sakaguchi K; Tsukada K; Teraoka H
Characterization of DNA ligase from the fungus Coprinus cinereus.
European journal of biochemistry / FEBS 1996;237(3):691-7.
1995: Kai M; Takahashi T; Todo T; Sakaguchi K
Novel DNA binding proteins highly specific to UV-damaged DNA sequences from embryos of Drosophila melanogaster.
Nucleic acids research 1995;23(14):2600-7.
1994: Takami K; Matsuda S; Sono A; Sakaguchi K
A meiotic DNA polymerase from a mushroom, Agaricus bisporus.
The Biochemical journal 1994;299 ( Pt 2)():335-40.
1994: Gomi K; Sakaguchi K
A new meiotic protein factor which enhances activity of meiotic DNA polymerase from Coprinus cinereus.
Biochemical and biophysical research communications 1994;198(3):1232-9.
1994: Aoyagi N; Matsuoka S; Furunobu A; Matsukage A; Sakaguchi K
Drosophila DNA polymerase delta. Purification and characterization.
The Journal of biological chemistry 1994;269(8):6045-50.
1993: Matsuda S; Takami K; Sono A; Sakaguchi K
A meiotic DNA polymerase from Coprinus cinereus: further purification and characterization.
Chromosoma 1993;102(9):631-6.

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